Background and activities
I am Head of the Department of Geriatrics, St Olav hospital and professor at the Department of Neuromedicine and movement science, Norwegian, University of Science and Technology (NTNU).
I completed medical studies in 1987 and specialties within internal medicine and geriatric medicine in 2000. My thesis "Treatment of acutely sick, frail elderly patient in a geriatric evaluation and management unit. Results from a prospective randomised study" was defended in 2006 at NTNU.
I have comprehensive experience in clinical work with geriatric patients referred to the hospital.
For many years, I have been teaching medical students at NTNU and I have also been teaching other students, health care professionals and public groups.
My research has focused mainly on comprehensive geriatric assessment and cognitive impairment (dementia and delirum) in the elderly. My thesis was a randomised study showing that acutely sick geriatric patients had benefit from treatment in an acute geriatric ward as compared to medical wards. Later we have also shown that home-dwelling hip fracture patients had benefit from treatment in a geriatric ward as compared to an orthopaedic ward, and that the treatment was cost-efficient. These results were published in the Lancet. We have now one ongoing study in collaboration with Innlandet hospital trust (PI is professor Marit Slaaen Jordhøy). In the cluster-randomised pilot study we investigate elderly cancer patients who get radiotherapy. In the LAST-long study we study follow-up of stroke patients and if functional decline can be prevented by offering geriatric assessment and a personilsed follow-up (PI is professor Torunn Askim).
In my research on elderly patients with cognitive impairment I have been involved in studies on progression of Alzheimers disease, acute delirium, risk factors for dementia and the association between cognition and motoric function. We are also part of the NorKOG network and recruiting patients being assessed for cognitive impairment and thereby also in the DemGene study that is focusing on genetics and dementia.
I am principal investigator of the Nor-COAST (Norwegian Cognitive Impairment After Stroke Study) is a multi centre study funded by the National Health association A total of 815 stroke patients are included at 5 different hospitals and are folllowed for three years, data collection will be finished in March 2020. 2017. There are several phd-students and postdocs and we expect several papers published in peer reviewed journals.
Scientific, academic and artistic work
A selection of recent journal publications, artistic productions, books, including book and report excerpts. See all publications in the database
- (2019) A MULTIMODAL INDIVIDUALIZED INTERVENTION TO PREVENT FUNCTIONAL DECLINE AFTER STROKE. A RANDOMISED CONTROLLED TRIAL ON LONG-TERM FOLLOW-UP AFTER STROKE (THE LAST-LONG TRIAL). European Stroke Journal. vol. 4 (1).
- (2019) Cortisol levels among older people with and without depression and dementia. International Psychogeriatrics. vol. 31 (4).
- (2019) Examining the association between genetic liability for schizophrenia and psychotic symptoms in Alzheimer's disease. Translational psychiatry. vol. 9:273.
- (2019) Motor activity across delirium motor subtypes in geriatric patients assessed using body-worn sensors: a Norwegian cross-sectional study. BMJ Open. vol. 9:e026401 (2).
- (2019) Delirium motor subtypes and prognosis in hospitalized geriatric patients ? A prospective observational study. Journal of Psychosomatic Research. vol. 122.
- (2019) Delirium og kognitiv svikt blant eldre i norske akuttmottak. Tidsskrift for Den norske legeforening. vol. 139 (6).
- (2019) Team approach: Multidisciplinary treatment of hip fractures in elderly patients: Orthogeriatric care. Journal of bone and joint surgery reviews (JBJS Reviews). vol. 7:e6 (6).
- (2019) Moderately increased albuminuria, chronic kidney disease and incident dementia: the HUNT study. BMC Nephrology. vol. 20:261.
- (2019) My husband is not ill; He has memory loss - Caregivers perspectives on health care services for persons with dementia. BMC Geriatrics. vol. 19 (1).
- (2019) The Association Between Circulating Inflammatory Markers and the Progression of Alzheimer Disease in Norwegian Memory Clinic Patients With Mild Cognitive Impairment or Dementia. Alzheimer Disease and Associated Disorders.
- (2019) Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk. Nature Genetics. vol. 51 (3).
- (2019) Modifiable factors affecting older patients' quality of life and physical function during cancer treatment. Journal of Geriatric Oncology. vol. 10 (6).
- (2019) Interdisciplinary care of hip fractures: Orthogeriatric models, alternative models, interdisciplinary teamwork. Baillière's Best Practice & Research : Clinical Rheumatology. vol. 33 (2).
- (2019) GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study. Scientific Reports. vol. 9.
- (2018) Association between vascular comorbidity and progression of Alzheimer's disease: a two-year observational study in Norwegian memory clinics. BMC Geriatrics. vol. 18:120.
- (2018) Environmental factors and risk of delirium in geriatric patients: An observational study. BMC Geriatrics. vol. 18 (1).
- (2018) The association of high sensitivity C-reactive protein and incident Alzheimer disease in patients 60 years and older: The HUNT study, Norway. Immunity & Ageing. vol. 15 (4).
- (2018) The Norwegian Cognitive impairment after stroke study (Nor-COAST): study protocol of a multicentre, prospective cohort study. BMC Neurology. vol. 18:193.
- (2018) Meta-analysis of Alzheimer’s disease on 9,751 samples from Norway and IGAP study identifies four risk loci. Scientific Reports. vol. 8.
- (2017) Trajectories of depressive symptoms and their relationship to the progression of dementia. Journal of Affective Disorders. vol. 222.