Ioanna Sandvig

About

Group leader, Integrative Neuroscience Group, Department of Neuromedicine and Movement Science, NTNU

President of the Norwegian Neuroscience Society (NNS), Governing Council member of FENS

Council Member, Nordic Neuroscience

Member: Society for Neuroscience (SfN); ALBA Network; Clinical-Academic Group for Alzheimer´s Disease

Research interests

The main research interest of our group is the study and elucidation of neuroplasticity mechanisms in the context of CNS damage and repair. Specifically, we model and investigate dynamic structure-function relationships in neuronal assemblies in healthy and perturbed conditions with the goal of identifying and engaging key aspects of complex neural network behaviour that determine adaptive or maladaptive neuroplasticity in the lesioned CNS, including injury and neurodegenerative disease.

Ongoing research activities focus on CNS lesion modelling through the integration of advanced theoretical concepts and interdisciplinary methods and tools. Apart from in vivo models, we work with in vitro and computational models that recapitulate and exploit fundamental attributes of biological neural networks, including self-organization over time into assemblies of increasing structural complexity, with concomitant emergence of complex functional dynamics.

Our working hypotheses are based on the relevance of specific identifiable network topologies as well as patterns of synaptic transmission for the functional capacity of a network in terms of plasticity, learning, and adaptability and, by the same token, for the initiation and spread of lesion-related pathologies in vivo and in vitro.

These research activities are coupled to clinical research by our group investigating dynamic neuroplasticity using connectomics and transcriptional analyses.

Publications

Selected publications

2026

Avci-Colak, Esin; Sandvig, Axel; Rohweder, Gitta; Sandvig, Ioanna. (2026) Through The Looking-Glass: Navigating Network Reorganization Across Lesion Damage In The Brain. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Avci-Colak, Esin; Rohweder, Gitta; Iandolo, Riccardo; Bommarito, Giulia; Sandvig, Ioanna; Sandvig, Axel. (2026) Structural connectome changes as biomarkers of stroke recovery: a longitudinal 7T MRI study. BMC Neuroscience
Academic article
Grønlie, Marthe Bendiksvoll; Fiskum, Vegard; Sandvig, Axel; Sandvig, Ioanna. (2026) Structural and Synaptic Dysregulation Drives Network Vulnerability in APOE4 Human Neuronal Networks. BioRxiv
Academic article
Fiskum, Vegard; Winter-Hjelm, Nicolai; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2026) Microscale dysfunction and mesoscale compensation in degenerating neuronal networks. Network Neuroscience
Academic article
Barker, Roger; Fiskum, Vegard; Hanssen, Katrine Sjaastad; Valderhaug, Vibeke Devold; Barbieri, Riccardo; Barbaro, Massimo; Matthews, Helen; Øksengård, Anne Rita; Sandvig, Ioanna; Sandvig, Axel. (2026) Addressing the effects of COVID-19 on Alzheimer´s and Parkinson´s disease patients (DEFINE). EU Joint Programme Neurodegenerative Disease Research (JPND)
Research report

2025

Lindell, Trym; Ramstad, Ola Huse; Sandvig, Ioanna; Sandvig, Axel; Nichele, Stefano. (2025) Information Encoding and Decoding in In Vitro Neural Networks on Micro Electrode Arrays through Stimulation Timing. International Journal of Unconventional Computing
Academic article
Kollstrøm, Anna Mikalsen; Sandvig, Ioanna; Fiskum, Vegard; Sandvig, Axel. (2025) Decoding neural adaptability in the face of adversity:Structural and functional dynamics of selforganized biological neural networks in response to neuropathology. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Winter-Hjelm, Nicolai; Isdal, Leik; Köllensperger, Peter; Sandvig, Axel; Sandvig, Ioanna; Sikorski, Pawel Tadeusz. (2025) Nanoporous platinum microelectrode arrays for neuroscience applications. RSC Advances
Academic article
Winter-Hjelm, Nicolai; Klausen, Kasper Grøndahl; Normann, Amund Stensrud; Sandvig, Axel; Sandvig, Ioanna; Sikorski, Pawel Tadeusz. (2025) Functional Complexity of Engineered Neural Networks Self-Organized on Structured 3D Interfaces. Small
Academic article
Kollstrøm, Anna Mikalsen; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2025) Dysregulation of synaptic transcripts underlies network abnormalities in ALS patient-derived motor neurons. American Journal of Physiology - Cell Physiology
Academic article
Kollstrøm, Anna Mikalsen; Grønlie, Marthe Bendiksvoll; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2025) Induced long-term potentiation improves synaptic stability and restores network function in ALS motor neurons. Neurobiology of Disease
Academic article

2024

Iandolo, Riccardo; Avci, Esin; Bommarito, Giulia; Sandvig, Ioanna; Rohweder, Gitta; Sandvig, Axel. (2024) Characterizing upper extremity fine motor function in the presence of white matter hyperintensities: A 7 T MRI cross-sectional study in older adults. NeuroImage: Clinical
Academic article
Fiskum, Vegard; Winter-Hjelm, Nicolai; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2024) ALS patient-derived motor neuron networks exhibit microscale dysfunction and mesoscale compensation rendering them highly vulnerable to perturbation. BioRxiv
Academic article
Hanssen, Katrine Sjaastad; Winter-Hjelm, Nicolai; Niethammer, Salome Nora; Kobro-Flatmoen, Asgeir; Witter, Menno Peter; Sandvig, Axel; Sandvig, Ioanna. (2024) Reverse engineering of feedforward cortical-Hippocampal microcircuits for modelling neural network function and dysfunction. Scientific Reports
Academic article
Christiansen, Nicholas; Sandvig, Ioanna; Sandvig, Axel. (2024) Reduced spatial spread of nodes in geometric network models improves topology associated with increased computational capabilities. BioRxiv
Academic article
Winter-Hjelm, Nicolai; Sikorski, Pawel Tadeusz; Sandvig, Axel; Sandvig, Ioanna. (2024) Engineered Cortical Microcircuits for Investigations of Neuroplasticity. BioRxiv
Academic article
Winter-Hjelm, Nicolai; Isdal, Leik; Köllensperger, Peter; Sandvig, Axel; Sandvig, Ioanna; Sikorski, Pawel Tadeusz. (2024) Nanoporous Platinum Microelectrodes for Neuroscience Applications. BioRxiv
Academic article
Valderhaug, Vibeke Devold; Ramstad, Ola Huse; van de Wijdeven, Rosanne Francisca; Heiney, Kristine; Nichele, Stefano; Sandvig, Axel; Sandvig, Ioanna. (2024) Micro-and mesoscale aspects of neurodegeneration in engineered human neural networks carrying the LRRK2 G2019S mutation. Frontiers in Cellular Neuroscience
Academic article
Schiro, Lars Erik; Sandvig, Ioanna; Sandvig, Axel. (2024) A regenerative crossroad within the niche: The role and potential of neural stem cells in traumatic CNS Injury. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Winter-Hjelm, Nicolai; Sikorski, Pawel Tadeusz; Sandvig, Axel; Sandvig, Ioanna. (2024) Engineered cortical microcircuits for investigations of neuroplasticity. Lab on a Chip
Academic article
Winter-Hjelm, Nicolai; Sandvig, Ioanna; Sandvig, Axel; Sikorski, Pawel. (2024) Bioengineered Neural Networks as Computational Systems: Designing Anatomically Inspired Microcircuits to Decode Neural Function and Dysfunction. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Weir, Janelle Shari; Hanssen, Katrine Sjaastad; Winter-Hjelm, Nicolai; Sandvig, Axel; Sandvig, Ioanna. (2024) Evolving alterations of structural organization and functional connectivity in feedforward neural networks after induced P301L tau mutation. European Journal of Neuroscience
Academic article
Weir, Janelle Shari; Sandvig, Ioanna; Sandvig, Axel. (2024) Motifs of order. Emergent Self-Organization and Complex Dynamics of Biological Neural Networks. NTNU
Doctoral thesis
Lindell, Trym; Ramstad, Ola Huse; Sandvig, Ioanna; Sandvig, Axel; Nichele, Stefano. (2024) Chaotic Time Series Prediction in Biological Neural Network Reservoirs on Microelectrode Arrays.
Academic chapter
Winter-Hjelm, Nicolai; Klausen, Kasper; Normann, Amund Stensrud; Sandvig, Axel; Sandvig, Ioanna; Sikorski, Pawel. (2024) Functional Complexity of Engineered Neural Networks Self-Organized on Novel 3D Interfaces. BioRxiv
Academic article
Schiro, Lars Erik; Bauer, Ulrich Stefan; Bjorkli, Christiana; Sandvig, Axel; Sandvig, Ioanna. (2024) In vitro survival and neurogenic potential of central canal-derived neural stem cells depend on spinal cord injury type. BioRxiv
Academic article
Schiro, Lars Erik; Bauer, Ulrich Stefan; Bjorkli, Christiana; Sandvig, Axel; Sandvig, Ioanna. (2024) Neural stem cells isolated from activated brain neurogenic niches after traumatic injury demonstrate distinct behaviors in vitro. BioRxiv
Academic article

2023

Hanssen, Katrine Sjaastad; Kobro-Flatmoen, Asgeir; Sandvig, Ioanna; Witter, Menno Peter. (2023) Dissecting the complexities of Alzheimer's disease: Engineering selectively vulnerable neural networks in vitro. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Fiskum, Vegard; Sandvig, Ioanna; Sandvig, Axel. (2023) Increased cost of living - Network scale motor neuron dysfunction in amyotrophic lateral sclerosis. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Weir, Janelle Shari; Ramstad, Ola Huse; Sandvig, Axel; Sandvig, Ioanna. (2023) Inhibition of excitatory synaptic transmission alters functional organization and efficiency in cortical neural networks. BioRxiv
Academic article
Weir, Janelle Shari; Hanssen, Katrine Sjaastad; Winter-Hjelm, Nicolai; Sandvig, Axel; Sandvig, Ioanna. (2023) Altered structural organization and functional connectivity in feedforward neural networks after induced perturbation. BioRxiv
Academic article
Winter-Hjelm, Nicolai; Tomren, Åste Brune; Sikorski, Pawel Tadeusz; Sandvig, Axel; Sandvig, Ioanna. (2023) Structure-function dynamics of engineered, modular neuronal networks with controllable afferent-efferent connectivity. Journal of Neural Engineering
Academic article
Hanssen, Katrine Sjaastad; Winter-Hjelm, Nicolai; Niethammer, Salome Nora; Kobro-Flatmoen, Asgeir; Witter, Menno Peter; Sandvig, Axel; Sandvig, Ioanna. (2023) Reverse Engineering of Feedforward Cortical-Hippocampal Neural Networks Relevant for Preclinical Disease Modelling. BioRxiv
Academic article
Sandvig, Axel; Caleo, Matteo; Sandvig, Ioanna. (2023) Criticality in neural network behavior and its implications for computational processing in healthy and perturbed conditions. Frontiers in Neural Circuits
Anthology
Weir, Janelle Shari; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2023) Selective inhibition of excitatory synaptic transmission alters the emergent bursting dynamics of in vitro neural networks. Frontiers in Neural Circuits
Academic article
Filho, Sidney Pontes; Nichele, Stefano; Yazidi, Anis; Zhang, Jianhua; Hammer, Hugo Lewi; Sandvig, Ioanna; Tufte, Gunnar. (2023) Optimization of dynamical systems towards criticality and intelligent behavior. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Heiney, Kristine; Nichele, Stefano; Sandvig, Ioanna; Tufte, Gunnar. (2023) Deciphering and emulating neuronal communication: Population-level computation from elemental interactions. NTNU
Doctoral thesis
Hanssen, Katrine Sjaastad; Witter, Menno Peter; Sandvig, Axel; Sandvig, Ioanna; Kobro-Flatmoen, Asgeir. (2023) Dissection and culturing of adult lateral entorhinal cortex layer II neurons from APP/PS1 Alzheimer model mice. Journal of Neuroscience Methods
Academic article

2022

Hanssen, Katrine Sjaastad; Witter, Menno; Sandvig, Axel; Sandvig, Ioanna; Kobro-Flatmoen, Asgeir. (2022) Microdissection and culturing of adult lateral authorial cortex layer II neurone from APP/PSI Alzheimer model mouse. BioRxiv
Academic article
Sandvig, Ioanna; Sandvig, Axel. (2022) Editorial: Criticality in neural network behavior and its implications for computational processing in healthy and perturbed conditions. Frontiers in Neural Circuits
Editorial
Bauer, Ulrich Stefan; Sandvig, Axel; Sandvig, Ioanna. (2022) Advanced cellular models for the recapitulation and study of neuropathology. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Bjorkli, Christiana; Sandvig, Ioanna; Sandvig, Axel; Witter, Menno. (2022) The inside-out of Alzheimer’s disease. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Bjorkli, Christiana; Hemler, Mary Elizabeth; Julian, Joshua B; Sandvig, Axel; Sandvig, Ioanna. (2022) Combined targeting of pathways regulating synaptic formation and autophagy attenuates Alzheimer’s disease pathology in mice. Frontiers in Pharmacology
Academic article
Winter-Hjelm, Nicolai; Tomren, Åste Brune; Sikorski, Pawel Tadeusz; Sandvig, Axel; Sandvig, Ioanna. (2022) Structure-Function Dynamics of Engineered, Modular Neuronal Networks with Controllable Afferent-Efferent Connectivity. BioRxiv
Academic article
Weir, Janelle Shari; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2022) Selective inhibition of excitatory synaptic transmission alters the emergent bursting dynamics of in vitro neural networks. BioRxiv
Academic article
Schiro, Lars Erik; Bauer, Ulrich Stefan; Sandvig, Axel; Sandvig, Ioanna. (2022) Isolation and comparison of neural stem cells from the adult rat brain and spinal cord canonical neurogenic niches. STAR Protocols
Academic article
Bjorkli, Christiana; Hemler, Mary Elisabeth; Julian, Joshua Benjamin; Sandvig, Axel; Sandvig, Ioanna. (2022) Using intracerebral microdialysis to probe the efficacy of repurposed drugs in Alzheimer’s disease pathology. BioRxiv
Academic article
Heiney, Kristine Anne; Ramstad, Ola Huse; Fiskum, Vegard; Sandvig, Axel; Sandvig, Ioanna; Nichele, Stefano. (2022) Neuronal avalanche dynamics and functional connectivity elucidate information propagation in vitro. Frontiers in Neural Circuits
Academic article
Bjørkli, Christiana; Ebbesen, Nora Cecilie; Julian, Joshua Benjamin; Witter, Menno; Sandvig, Axel; Sandvig, Ioanna. (2022) Manipulation of neuronal activity in the entorhinal-hippocampal circuit affects intraneuronal amyloid-β levels. BioRxiv
Academic article
Bauer, Ulrich Stefan; Fiskum, Vegard; Raveendran Nair, Rajeevkumar; Wijdeven, Rosanne Francisca van de; Kentros, Clifford; Sandvig, Ioanna; Sandvig, Axel. (2022) Validation of Functional Connectivity of Engineered Neuromuscular Junction With Recombinant Monosynaptic Pseudotyped ΔG-Rabies Virus Tracing. Frontiers in Integrative Neuroscience
Academic article

2021

Levi, Riccardo; Valderhaug, Vibeke Devold; Castelbuono, Salvatore; Sandvig, Axel; Sandvig, Ioanna; Barbieri, Riccardo. (2021) Bayesian supervised machine learning classification of neural networks with pathological perturbations. Biomedical Engineering & Physics Express
Academic article
Bjorkli, Christiana; Louet, Claire; Flo, Trude Helen; Hemler, Mary Elizabeth; Sandvig, Axel; Sandvig, Ioanna. (2021) In Vivo Microdialysis in Mice Captures Changes in Alzheimer´s Disease Cerebrospinal Fluid Biomarkers Consistent with Developing Pathology. Journal of Alzheimer's Disease
Academic article
Fiskum, Vegard; Sandvig, Axel; Sandvig, Ioanna. (2021) Silencing of activity during hypoxia improves functional outcomes in motor neuron networks in vitro. Frontiers in Integrative Neuroscience
Academic article
Valderhaug, Vibeke Devold; Heiney, Kristine; Ramstad, Ola Huse; Bråthen, Geir; Kuan, Wei-Li; Nichele, Stefano; Sandvig, Axel; Sandvig, Ioanna. (2021) Early functional changes associated with alpha-synuclein proteinopathy in engineered human neural networks. American Journal of Physiology - Cell Physiology
Academic article
Heiney, Kristine Anne; Valderhaug, Vibeke Devold; Ramstad, Ola Huse; Sandvig, Ioanna; Sandvig, Axel; Nichele, Stefano. (2021) Hallmarks of Criticality in Neuronal Networks Depend on Cell Type and the Temporal Resolution of Neuronal Avalanches. International Journal of Unconventional Computing
Academic article
Heiney, Kristine; Ramstad, Ola Huse; Fiskum, Vegard; Christiansen, Nicholas; Sandvig, Axel; Nichele, Stefano; Sandvig, Ioanna. (2021) Criticality, connectivity, and neural disorder: A multifaceted approach to neural computation. Frontiers in Computational Neuroscience
Academic literature review

2020

Bjorkli, Christiana; Sandvig, Axel; Sandvig, Ioanna. (2020) Bridging the gap between fluid biomarkers for Alzheimer’s disease, model systems, and patients. Frontiers in Aging Neuroscience
Academic literature review
Pontes-Filho, Sidney; Lind, Pedro; Yazidi, Anis; Zhang, Jianhua; Hammer, Hugo Lewi; Mello, Gustavo; Sandvig, Ioanna; Tufte, Gunnar; Nichele, Stefano. (2020) EvoDynamic: A Framework for the Evolution of Generally Represented Dynamical Systems and Its Application to Criticality.
Academic chapter
Pontes-Filho, Sidney; Lind, Pedro; Yazidi, Anis; Zhang, Jianhua; Hammer, Hugo Lewi; Mello, Gustavo; Sandvig, Ioanna; Tufte, Gunnar; Nichele, Stefano. (2020) A neuro-inspired general framework for the evolution of stochastic dynamical systems: Cellular automata, random Boolean networks and echo state networks towards criticality. Cognitive Neurodynamics
Academic article
Mello, Gustavo; Pontes-Filho, Sidney; Sandvig, Ioanna; Valderhaug, Vibeke Devold; Zouganeli, Evi; Ramstad, Ola Huse; Sandvig, Axel; Nichele, Stefano. (2020) Method to Obtain Neuromorphic Reservoir Networks from Images of in Vitro Cortical Networks.
Academic chapter
Valderhaug, Vibeke Devold; Ramstad, Ola Huse; van de Wijdeven, Rosanne Francisca; Heiney, Kristine; Nichele, Stefano; Sandvig, Axel; Sandvig, Ioanna. (2020) Structural and functional alterations associated with the LRRK2 G2019S mutation revealed in structured human neural networks. BioRxiv
Academic article
Valderhaug, Vibeke Devold; Heiney, Kristine; Ramstad, Ola Huse; Bråthen, Geir; Kuan, Wei-Li; Nichele, Stefano; Sandvig, Axel; Sandvig, Ioanna. (2020) Criticality as a measure of developing proteinopathy in engineered human neural networks. BioRxiv
Academic article
Valderhaug, Vibeke Devold; Sandvig, Ioanna; Sandvig, Axel. (2020) Structure-function relationships in biological neural networks and the influence of neurodegenerative processes on such dynamics. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Sandvig, Axel; Sandvig, Ioanna; Tufte, Gunnar; Ramstad, Ola Huse. (2020) Neural disorder at the edge of chaos. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Heiney, Kristine; Ramstad, Ola Huse; Sandvig, Ioanna; Sandvig, Axel; Nichele, Stefano. (2020) Assessment and manipulation of the computational capacity of in vitro neuronal networks through criticality in neuronal avalanches.
Academic chapter

2019

Pontes-Filho, Sidney; Yazidi, Anis; Zhang, Jianhua; Hammer, Hugo Lewi; Mello, Gustavo; Sandvig, Ioanna; Nichele, Stefano; Tufte, Gunnar. (2019) A general representation of dynamical systems for reservoir computing.
Academic chapter
van de Wijdeven, Rosanne Francisca; Ramstad, Ola Huse; Valderhaug, Vibeke Devold; Köllensperger, Peter; Sandvig, Axel; Sandvig, Ioanna; Halaas, Øyvind. (2019) A novel lab-on-chip platform enabling axotomy and neuromodulation in a multi-nodal network. Biosensors and Bioelectronics
Academic article
Sandvig, Axel; Sandvig, Ioanna. (2019) Connectomics of morphogenetically engineered neurons as a predictor of functional integration in the ischemic brain. Frontiers in Neurology
Academic literature review
Bauer, Ulrich Stefan; van de Wijdeven, Rosanne Francisca; Raveendran Nair, Rajeevkumar; Fiskum, Vegard; Kentros, Clifford; Sandvig, Ioanna; Sandvig, Axel. (2019) Modelling functional human neuromuscular junctions in a differentially-perturbable microfluidic environment, validated through recombinant monosynaptic pseudotyped ΔG-rabies virus tracing. BioRxiv
Academic article
Valderhaug, Vibeke Devold; Glomm, Wilhelm; Sandru, Eugenia-Mariana; Yasuda, Masahiro; Sandvig, Axel; Sandvig, Ioanna. (2019) Formation of neural networks with structural and functional features consistent with small-world network topology on surface-grafted polymer particles. Royal Society Open Science
Academic article

Journal publications

Avci-Colak, Esin; Rohweder, Gitta; Iandolo, Riccardo; Bommarito, Giulia; Sandvig, Ioanna; Sandvig, Axel. (2026) Structural connectome changes as biomarkers of stroke recovery: a longitudinal 7T MRI study. BMC Neuroscience
Academic article
Grønlie, Marthe Bendiksvoll; Fiskum, Vegard; Sandvig, Axel; Sandvig, Ioanna. (2026) Structural and Synaptic Dysregulation Drives Network Vulnerability in APOE4 Human Neuronal Networks. BioRxiv
Academic article
Fiskum, Vegard; Winter-Hjelm, Nicolai; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2026) Microscale dysfunction and mesoscale compensation in degenerating neuronal networks. Network Neuroscience
Academic article
Lindell, Trym; Ramstad, Ola Huse; Sandvig, Ioanna; Sandvig, Axel; Nichele, Stefano. (2025) Information Encoding and Decoding in In Vitro Neural Networks on Micro Electrode Arrays through Stimulation Timing. International Journal of Unconventional Computing
Academic article
Iandolo, Riccardo; Avci, Esin; Bommarito, Giulia; Sandvig, Ioanna; Rohweder, Gitta; Sandvig, Axel. (2024) Characterizing upper extremity fine motor function in the presence of white matter hyperintensities: A 7 T MRI cross-sectional study in older adults. NeuroImage: Clinical
Academic article
Winter-Hjelm, Nicolai; Isdal, Leik; Köllensperger, Peter; Sandvig, Axel; Sandvig, Ioanna; Sikorski, Pawel Tadeusz. (2025) Nanoporous platinum microelectrode arrays for neuroscience applications. RSC Advances
Academic article
Hanssen, Katrine Sjaastad; Witter, Menno; Sandvig, Axel; Sandvig, Ioanna; Kobro-Flatmoen, Asgeir. (2022) Microdissection and culturing of adult lateral authorial cortex layer II neurone from APP/PSI Alzheimer model mouse. BioRxiv
Academic article
Weir, Janelle Shari; Ramstad, Ola Huse; Sandvig, Axel; Sandvig, Ioanna. (2023) Inhibition of excitatory synaptic transmission alters functional organization and efficiency in cortical neural networks. BioRxiv
Academic article
Fiskum, Vegard; Winter-Hjelm, Nicolai; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2024) ALS patient-derived motor neuron networks exhibit microscale dysfunction and mesoscale compensation rendering them highly vulnerable to perturbation. BioRxiv
Academic article
Weir, Janelle Shari; Hanssen, Katrine Sjaastad; Winter-Hjelm, Nicolai; Sandvig, Axel; Sandvig, Ioanna. (2023) Altered structural organization and functional connectivity in feedforward neural networks after induced perturbation. BioRxiv
Academic article
Sandvig, Ioanna; Sandvig, Axel. (2022) Editorial: Criticality in neural network behavior and its implications for computational processing in healthy and perturbed conditions. Frontiers in Neural Circuits
Editorial
Winter-Hjelm, Nicolai; Tomren, Åste Brune; Sikorski, Pawel Tadeusz; Sandvig, Axel; Sandvig, Ioanna. (2023) Structure-function dynamics of engineered, modular neuronal networks with controllable afferent-efferent connectivity. Journal of Neural Engineering
Academic article
Hanssen, Katrine Sjaastad; Winter-Hjelm, Nicolai; Niethammer, Salome Nora; Kobro-Flatmoen, Asgeir; Witter, Menno Peter; Sandvig, Axel; Sandvig, Ioanna. (2024) Reverse engineering of feedforward cortical-Hippocampal microcircuits for modelling neural network function and dysfunction. Scientific Reports
Academic article
Levi, Riccardo; Valderhaug, Vibeke Devold; Castelbuono, Salvatore; Sandvig, Axel; Sandvig, Ioanna; Barbieri, Riccardo. (2021) Bayesian supervised machine learning classification of neural networks with pathological perturbations. Biomedical Engineering & Physics Express
Academic article
Bjorkli, Christiana; Hemler, Mary Elizabeth; Julian, Joshua B; Sandvig, Axel; Sandvig, Ioanna. (2022) Combined targeting of pathways regulating synaptic formation and autophagy attenuates Alzheimer’s disease pathology in mice. Frontiers in Pharmacology
Academic article
Bjorkli, Christiana; Louet, Claire; Flo, Trude Helen; Hemler, Mary Elizabeth; Sandvig, Axel; Sandvig, Ioanna. (2021) In Vivo Microdialysis in Mice Captures Changes in Alzheimer´s Disease Cerebrospinal Fluid Biomarkers Consistent with Developing Pathology. Journal of Alzheimer's Disease
Academic article
Christiansen, Nicholas; Sandvig, Ioanna; Sandvig, Axel. (2024) Reduced spatial spread of nodes in geometric network models improves topology associated with increased computational capabilities. BioRxiv
Academic article
Winter-Hjelm, Nicolai; Sikorski, Pawel Tadeusz; Sandvig, Axel; Sandvig, Ioanna. (2024) Engineered Cortical Microcircuits for Investigations of Neuroplasticity. BioRxiv
Academic article
Bjorkli, Christiana; Sandvig, Axel; Sandvig, Ioanna. (2020) Bridging the gap between fluid biomarkers for Alzheimer’s disease, model systems, and patients. Frontiers in Aging Neuroscience
Academic literature review
Winter-Hjelm, Nicolai; Isdal, Leik; Köllensperger, Peter; Sandvig, Axel; Sandvig, Ioanna; Sikorski, Pawel Tadeusz. (2024) Nanoporous Platinum Microelectrodes for Neuroscience Applications. BioRxiv
Academic article
Winter-Hjelm, Nicolai; Tomren, Åste Brune; Sikorski, Pawel Tadeusz; Sandvig, Axel; Sandvig, Ioanna. (2022) Structure-Function Dynamics of Engineered, Modular Neuronal Networks with Controllable Afferent-Efferent Connectivity. BioRxiv
Academic article
Hanssen, Katrine Sjaastad; Winter-Hjelm, Nicolai; Niethammer, Salome Nora; Kobro-Flatmoen, Asgeir; Witter, Menno Peter; Sandvig, Axel; Sandvig, Ioanna. (2023) Reverse Engineering of Feedforward Cortical-Hippocampal Neural Networks Relevant for Preclinical Disease Modelling. BioRxiv
Academic article
Winter-Hjelm, Nicolai; Klausen, Kasper Grøndahl; Normann, Amund Stensrud; Sandvig, Axel; Sandvig, Ioanna; Sikorski, Pawel Tadeusz. (2025) Functional Complexity of Engineered Neural Networks Self-Organized on Structured 3D Interfaces. Small
Academic article
Valderhaug, Vibeke Devold; Ramstad, Ola Huse; van de Wijdeven, Rosanne Francisca; Heiney, Kristine; Nichele, Stefano; Sandvig, Axel; Sandvig, Ioanna. (2024) Micro-and mesoscale aspects of neurodegeneration in engineered human neural networks carrying the LRRK2 G2019S mutation. Frontiers in Cellular Neuroscience
Academic article
Weir, Janelle Shari; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2023) Selective inhibition of excitatory synaptic transmission alters the emergent bursting dynamics of in vitro neural networks. Frontiers in Neural Circuits
Academic article
Pontes-Filho, Sidney; Lind, Pedro; Yazidi, Anis; Zhang, Jianhua; Hammer, Hugo Lewi; Mello, Gustavo; Sandvig, Ioanna; Tufte, Gunnar; Nichele, Stefano. (2020) A neuro-inspired general framework for the evolution of stochastic dynamical systems: Cellular automata, random Boolean networks and echo state networks towards criticality. Cognitive Neurodynamics
Academic article
van de Wijdeven, Rosanne Francisca; Ramstad, Ola Huse; Valderhaug, Vibeke Devold; Köllensperger, Peter; Sandvig, Axel; Sandvig, Ioanna; Halaas, Øyvind. (2019) A novel lab-on-chip platform enabling axotomy and neuromodulation in a multi-nodal network. Biosensors and Bioelectronics
Academic article
Sandvig, Axel; Sandvig, Ioanna. (2019) Connectomics of morphogenetically engineered neurons as a predictor of functional integration in the ischemic brain. Frontiers in Neurology
Academic literature review
Valderhaug, Vibeke Devold; Ramstad, Ola Huse; van de Wijdeven, Rosanne Francisca; Heiney, Kristine; Nichele, Stefano; Sandvig, Axel; Sandvig, Ioanna. (2020) Structural and functional alterations associated with the LRRK2 G2019S mutation revealed in structured human neural networks. BioRxiv
Academic article
Bauer, Ulrich Stefan; van de Wijdeven, Rosanne Francisca; Raveendran Nair, Rajeevkumar; Fiskum, Vegard; Kentros, Clifford; Sandvig, Ioanna; Sandvig, Axel. (2019) Modelling functional human neuromuscular junctions in a differentially-perturbable microfluidic environment, validated through recombinant monosynaptic pseudotyped ΔG-rabies virus tracing. BioRxiv
Academic article
Valderhaug, Vibeke Devold; Heiney, Kristine; Ramstad, Ola Huse; Bråthen, Geir; Kuan, Wei-Li; Nichele, Stefano; Sandvig, Axel; Sandvig, Ioanna. (2020) Criticality as a measure of developing proteinopathy in engineered human neural networks. BioRxiv
Academic article
Weir, Janelle Shari; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2022) Selective inhibition of excitatory synaptic transmission alters the emergent bursting dynamics of in vitro neural networks. BioRxiv
Academic article
Fiskum, Vegard; Sandvig, Axel; Sandvig, Ioanna. (2021) Silencing of activity during hypoxia improves functional outcomes in motor neuron networks in vitro. Frontiers in Integrative Neuroscience
Academic article
Schiro, Lars Erik; Bauer, Ulrich Stefan; Sandvig, Axel; Sandvig, Ioanna. (2022) Isolation and comparison of neural stem cells from the adult rat brain and spinal cord canonical neurogenic niches. STAR Protocols
Academic article
Bjorkli, Christiana; Hemler, Mary Elisabeth; Julian, Joshua Benjamin; Sandvig, Axel; Sandvig, Ioanna. (2022) Using intracerebral microdialysis to probe the efficacy of repurposed drugs in Alzheimer’s disease pathology. BioRxiv
Academic article
Winter-Hjelm, Nicolai; Sikorski, Pawel Tadeusz; Sandvig, Axel; Sandvig, Ioanna. (2024) Engineered cortical microcircuits for investigations of neuroplasticity. Lab on a Chip
Academic article
Weir, Janelle Shari; Hanssen, Katrine Sjaastad; Winter-Hjelm, Nicolai; Sandvig, Axel; Sandvig, Ioanna. (2024) Evolving alterations of structural organization and functional connectivity in feedforward neural networks after induced P301L tau mutation. European Journal of Neuroscience
Academic article
Valderhaug, Vibeke Devold; Heiney, Kristine; Ramstad, Ola Huse; Bråthen, Geir; Kuan, Wei-Li; Nichele, Stefano; Sandvig, Axel; Sandvig, Ioanna. (2021) Early functional changes associated with alpha-synuclein proteinopathy in engineered human neural networks. American Journal of Physiology - Cell Physiology
Academic article
Heiney, Kristine Anne; Ramstad, Ola Huse; Fiskum, Vegard; Sandvig, Axel; Sandvig, Ioanna; Nichele, Stefano. (2022) Neuronal avalanche dynamics and functional connectivity elucidate information propagation in vitro. Frontiers in Neural Circuits
Academic article
Valderhaug, Vibeke Devold; Glomm, Wilhelm; Sandru, Eugenia-Mariana; Yasuda, Masahiro; Sandvig, Axel; Sandvig, Ioanna. (2019) Formation of neural networks with structural and functional features consistent with small-world network topology on surface-grafted polymer particles. Royal Society Open Science
Academic article
Bjørkli, Christiana; Ebbesen, Nora Cecilie; Julian, Joshua Benjamin; Witter, Menno; Sandvig, Axel; Sandvig, Ioanna. (2022) Manipulation of neuronal activity in the entorhinal-hippocampal circuit affects intraneuronal amyloid-β levels. BioRxiv
Academic article
Hanssen, Katrine Sjaastad; Witter, Menno Peter; Sandvig, Axel; Sandvig, Ioanna; Kobro-Flatmoen, Asgeir. (2023) Dissection and culturing of adult lateral entorhinal cortex layer II neurons from APP/PS1 Alzheimer model mice. Journal of Neuroscience Methods
Academic article
Bauer, Ulrich Stefan; Fiskum, Vegard; Raveendran Nair, Rajeevkumar; Wijdeven, Rosanne Francisca van de; Kentros, Clifford; Sandvig, Ioanna; Sandvig, Axel. (2022) Validation of Functional Connectivity of Engineered Neuromuscular Junction With Recombinant Monosynaptic Pseudotyped ΔG-Rabies Virus Tracing. Frontiers in Integrative Neuroscience
Academic article
Winter-Hjelm, Nicolai; Klausen, Kasper; Normann, Amund Stensrud; Sandvig, Axel; Sandvig, Ioanna; Sikorski, Pawel. (2024) Functional Complexity of Engineered Neural Networks Self-Organized on Novel 3D Interfaces. BioRxiv
Academic article
Kollstrøm, Anna Mikalsen; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2025) Dysregulation of synaptic transcripts underlies network abnormalities in ALS patient-derived motor neurons. American Journal of Physiology - Cell Physiology
Academic article
Heiney, Kristine Anne; Valderhaug, Vibeke Devold; Ramstad, Ola Huse; Sandvig, Ioanna; Sandvig, Axel; Nichele, Stefano. (2021) Hallmarks of Criticality in Neuronal Networks Depend on Cell Type and the Temporal Resolution of Neuronal Avalanches. International Journal of Unconventional Computing
Academic article
Schiro, Lars Erik; Bauer, Ulrich Stefan; Bjorkli, Christiana; Sandvig, Axel; Sandvig, Ioanna. (2024) In vitro survival and neurogenic potential of central canal-derived neural stem cells depend on spinal cord injury type. BioRxiv
Academic article
Schiro, Lars Erik; Bauer, Ulrich Stefan; Bjorkli, Christiana; Sandvig, Axel; Sandvig, Ioanna. (2024) Neural stem cells isolated from activated brain neurogenic niches after traumatic injury demonstrate distinct behaviors in vitro. BioRxiv
Academic article
Kollstrøm, Anna Mikalsen; Grønlie, Marthe Bendiksvoll; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2025) Induced long-term potentiation improves synaptic stability and restores network function in ALS motor neurons. Neurobiology of Disease
Academic article
Heiney, Kristine; Ramstad, Ola Huse; Fiskum, Vegard; Christiansen, Nicholas; Sandvig, Axel; Nichele, Stefano; Sandvig, Ioanna. (2021) Criticality, connectivity, and neural disorder: A multifaceted approach to neural computation. Frontiers in Computational Neuroscience
Academic literature review

Books

Sandvig, Axel; Caleo, Matteo; Sandvig, Ioanna. (2023) Criticality in neural network behavior and its implications for computational processing in healthy and perturbed conditions. Frontiers in Neural Circuits
Anthology

Part of book/report

Pontes-Filho, Sidney; Yazidi, Anis; Zhang, Jianhua; Hammer, Hugo Lewi; Mello, Gustavo; Sandvig, Ioanna; Nichele, Stefano; Tufte, Gunnar. (2019) A general representation of dynamical systems for reservoir computing.
Academic chapter
Pontes-Filho, Sidney; Lind, Pedro; Yazidi, Anis; Zhang, Jianhua; Hammer, Hugo Lewi; Mello, Gustavo; Sandvig, Ioanna; Tufte, Gunnar; Nichele, Stefano. (2020) EvoDynamic: A Framework for the Evolution of Generally Represented Dynamical Systems and Its Application to Criticality.
Academic chapter
Mello, Gustavo; Pontes-Filho, Sidney; Sandvig, Ioanna; Valderhaug, Vibeke Devold; Zouganeli, Evi; Ramstad, Ola Huse; Sandvig, Axel; Nichele, Stefano. (2020) Method to Obtain Neuromorphic Reservoir Networks from Images of in Vitro Cortical Networks.
Academic chapter
Heiney, Kristine; Ramstad, Ola Huse; Sandvig, Ioanna; Sandvig, Axel; Nichele, Stefano. (2020) Assessment and manipulation of the computational capacity of in vitro neuronal networks through criticality in neuronal avalanches.
Academic chapter
Lindell, Trym; Ramstad, Ola Huse; Sandvig, Ioanna; Sandvig, Axel; Nichele, Stefano. (2024) Chaotic Time Series Prediction in Biological Neural Network Reservoirs on Microelectrode Arrays.
Academic chapter

Report

Barker, Roger; Fiskum, Vegard; Hanssen, Katrine Sjaastad; Valderhaug, Vibeke Devold; Barbieri, Riccardo; Barbaro, Massimo; Matthews, Helen; Øksengård, Anne Rita; Sandvig, Ioanna; Sandvig, Axel. (2026) Addressing the effects of COVID-19 on Alzheimer´s and Parkinson´s disease patients (DEFINE). EU Joint Programme Neurodegenerative Disease Research (JPND)
Research report

Student thesis or dissertation

Avci-Colak, Esin; Sandvig, Axel; Rohweder, Gitta; Sandvig, Ioanna. (2026) Through The Looking-Glass: Navigating Network Reorganization Across Lesion Damage In The Brain. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Kollstrøm, Anna Mikalsen; Sandvig, Ioanna; Fiskum, Vegard; Sandvig, Axel. (2025) Decoding neural adaptability in the face of adversity:Structural and functional dynamics of selforganized biological neural networks in response to neuropathology. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Hanssen, Katrine Sjaastad; Kobro-Flatmoen, Asgeir; Sandvig, Ioanna; Witter, Menno Peter. (2023) Dissecting the complexities of Alzheimer's disease: Engineering selectively vulnerable neural networks in vitro. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Fiskum, Vegard; Sandvig, Ioanna; Sandvig, Axel. (2023) Increased cost of living - Network scale motor neuron dysfunction in amyotrophic lateral sclerosis. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Bauer, Ulrich Stefan; Sandvig, Axel; Sandvig, Ioanna. (2022) Advanced cellular models for the recapitulation and study of neuropathology. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Bjorkli, Christiana; Sandvig, Ioanna; Sandvig, Axel; Witter, Menno. (2022) The inside-out of Alzheimer’s disease. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Schiro, Lars Erik; Sandvig, Ioanna; Sandvig, Axel. (2024) A regenerative crossroad within the niche: The role and potential of neural stem cells in traumatic CNS Injury. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Winter-Hjelm, Nicolai; Sandvig, Ioanna; Sandvig, Axel; Sikorski, Pawel. (2024) Bioengineered Neural Networks as Computational Systems: Designing Anatomically Inspired Microcircuits to Decode Neural Function and Dysfunction. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Filho, Sidney Pontes; Nichele, Stefano; Yazidi, Anis; Zhang, Jianhua; Hammer, Hugo Lewi; Sandvig, Ioanna; Tufte, Gunnar. (2023) Optimization of dynamical systems towards criticality and intelligent behavior. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Weir, Janelle Shari; Sandvig, Ioanna; Sandvig, Axel. (2024) Motifs of order. Emergent Self-Organization and Complex Dynamics of Biological Neural Networks. NTNU
Doctoral thesis
Valderhaug, Vibeke Devold; Sandvig, Ioanna; Sandvig, Axel. (2020) Structure-function relationships in biological neural networks and the influence of neurodegenerative processes on such dynamics. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Sandvig, Axel; Sandvig, Ioanna; Tufte, Gunnar; Ramstad, Ola Huse. (2020) Neural disorder at the edge of chaos. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Heiney, Kristine; Nichele, Stefano; Sandvig, Ioanna; Tufte, Gunnar. (2023) Deciphering and emulating neuronal communication: Population-level computation from elemental interactions. NTNU
Doctoral thesis

Teaching

Courses

Outreach

2026

Lecture

Sandvig, Ioanna. (2026) Modelling and decoding pathological dynamics across neural systems. Rudbeck Seminar Series, Uppsala University
Other presentation

Tsamis, Konstantinos; Sandvig, Ioanna; Mytilinaios, Dimitris; Mbellos, Stefanos; Manis, Giorgos. (2026) Brain, Aging, Memory, Plasticity, AI. Brain Awareness Week - Roundtable Scientific Discussion
Lecture

Sandvig, Ioanna. (2026) From Neurons to Networks:Principles of Neural Circuit Organization and Axon Guidance. Brain Awareness Week
Conference lecture

Sandvig, Ioanna. (2026) Brain network reorganisation in the presence of white matter hyperintensities. Ultra High-Field Imaging Symposium: Preprocessing and Quantitative MRI

2025

Conference poster

Kollstrøm, Anna Mikalsen; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2025) Early synaptic dysfunction contributes to network-wide structural and functional disruptions in motor neurons derived from an ALS patient. FENS Regional Meeting 2025
Lecture

Sandvig, Ioanna. (2025) Reverse-engineered brain microcircuits as models of neural function and dysfunction. The Limbic Structures of the Brain. From Bench to Bedside
Conference poster

Grønlie, Marthe Bendiksvoll; Kollstrøm, Anna Mikalsen; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2025) Synaptic Potentiation Stabilizes Structural and Functional Network Abnormalities in ALS Motor Neurons. FENS Regional Meeting 2025
Conference lecture

Hanssen, Katrine Sjaastad; Winter-Hjelm, Nicolai; Weir, Janelle Shari; Sandvig, Axel; Sandvig, Ioanna. (2025) Engineered Neural Networks for Alzheimer’s Disease Modelling. 13th International Meeting on Neural and Electrogenic Cell Interfacing (MEA 2025)
Conference poster

Hanssen, Katrine Sjaastad; Winter-Hjelm, Nicolai; Weir, Janelle Shari; Sandvig, Axel; Sandvig, Ioanna. (2025) Engineered Neural Networks for Alzheimer’s Disease Modelling. FENS Regional Meeting 2025
Conference poster

Fiskum, Vegard; Winter-Hjelm, Nicolai; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2025) Microscale dysfunction and mesoscale compensation in degenerating neuronal networks. FENS Regional Meeting 2025

2024

Conference poster

Valderhaug, Vibeke Devold; Ramstad, Ola Huse; Wijdeven, Rosanne Francisca van de; Heiney, Kristine; Nichele, Stefano; Sandvig, Ioanna; Sandvig, Axel. (2024) MICRO- AND MESOSCALE ASPECTS OF NEURODEGENERATION IN MULT-NODAL HUMAN NEURAL NETWORKS CARRYING THE LRRK2 G2019S MUTATION. AD/PD24TM: 18th International Conference on Alzheimers & Parkinsons Disease
Conference poster

Winter-Hjelm, Nicolai; Hanssen, Katrine Sjaastad; Fiskum, Vegard; Kollstrøm, Anna Mikalsen; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2024) Reverse engineered neural circuit motifs as computational substrates. The Brain Conference - Circuits for Movement
Conference lecture

Sandvig, Ioanna. (2024) Reverse engineering of complex neural networks in the study of physiological behaviours and pathological alterations. Alzheimer's disease and dementias SiG
Conference lecture

Hanssen, Katrine Sjaastad; Klausen, Kasper; Tomren, Åste Brune; Normann, Amund Stensrud; Sandvig, Axel; Sikorski, Pawel; Sandvig, Ioanna. (2024) Advanced Interfaces for Investigating the Impact of Topology on the Functional Dynamics of Engineered Neural Networks. Maxwell Summit 2024
Conference poster

Winter-Hjelm, Nicolai; Hanssen, Katrine Sjaastad; Klausen, Kasper; Tomren, Åste Brune; Normann, Amund Stensrud; Sandvig, Axel; Sikorski, Pawel; Sandvig, Ioanna. (2024) Advanced Interfaces for Investigating the Impact of Topology on the Functional Dynamics of Engineered Neural Networks. 4th In-Vitro 2D & 3D Neuronal Networks Summit
Conference poster

Ramstad, Ola Huse; Wijdeven, Rosanne Francisca van de; Heiney, Kristine; Nichele, Stefano; Sandvig, Axel; Sandvig, Ioanna. (2024) MICRO- AND MESOSCALE ASPECTS OF NEURODEGENERATION IN MULT-NODAL HUMAN NEURAL NETWORKS CARRYING THE LRRK2 G2019S MUTATION. AD/PD24TM: 18th International Conference on Alzheimers & Parkinsons Disease
Conference poster

Ramstad, Ola Huse; Wijdeven, Rosanne Francisca van de; Heiney, Kristine; Nichele, Stefano; Sandvig, Axel; Sandvig, Ioanna. (2024) MICRO- AND MESOSCALE ASPECTS OF NEURODEGENERATION IN MULTI-NODAL HUMAN NEURAL NETWORKS CARRYING THE LRRK2 G2019S MUTATION. AD/PD24TM: 18th International Conference on Alzheimers & Parkinsons Disease
Conference poster

Christiansen, Nicholas; Sandvig, Ioanna; Sandvig, Axel. (2024) Optimized neuron placement increases network topology related to improved computational capabilities. 4th Nordic Neuroscience Meeting
Conference lecture

Reimers, Felix Simon; Ramstad, Ola Huse; Sæbø, Solve; Sandvig, Axel; Sandvig, Ioanna; Nichele, Stefano. (2024) Examination of Computational Performance of Biological Neural Networks with Reservoir Computing. NORA annual conference 2024
Conference lecture

Reimers, Felix Simon; Ramstad, Ola Huse; Sæbø, Solve; Sandvig, Axel; Sandvig, Ioanna; Nichele, Stefano. (2024) Performance of C.Elegans Connectomes as Computational Reservoirs. NORA NeuroAI Workshop
Conference poster

Hanssen, Katrine Sjaastad; Klausen, Kasper; Tomren, Åste Brune; Normann, Amund Stensrud; Sandvig, Axel; Sikorski, Pawel Tadeusz; Sandvig, Ioanna. (2024) Advanced Interfaces for Investigating the Impact of Topology on the Functional Dynamics of Engineered Neural Networks. 4th In-Vitro 2D & 3D Neuronal Networks Summit
Conference lecture

Winter-Hjelm, Nicolai; Hanssen, Katrine Sjaastad; Klausen, Kasper; Tomren, Åste Brune; Normann, Amund Stensrud; Sandvig, Axel; Sikorski, Pawel Tadeusz; Sandvig, Ioanna. (2024) Advanced Interfaces for Investigating the Impact of Topology on the Functional Dynamics of Engineered Neural Networks. 4th In-Vitro 2D & 3D Neuronal Networks Summit
Conference poster

Hanssen, Katrine Sjaastad; Klausen, Kasper; Tomren, Åste Brune; Normann, Amund Stensrud; Sandvig, Axel; Sikorski, Pawel Tadeusz; Sandvig, Ioanna. (2024) Advanced Interfaces for Investigating the Impact of Topology on the Functional Dynamics of Engineered Neural Networks. Nordic NanoLab User Meeting 2024
Conference poster

Kollstrøm, Anna Mikalsen; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2024) Longitudinal assessment of ALS patient-derived motor neurons reveals altered network dynamics and synaptic impairment. FENS Forum 2024
Conference poster

Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2024) Longitudinal assessment of ALS patient-derived motor neurons reveals altered network dynamics and synaptic impairment. FENS Forum 2024
Conference lecture

Sandvig, Axel; Sikorski, Pawel Tadeusz; Sandvig, Ioanna. (2024) Engineered Cortical Microcircuits for Investigations of Neuroplasticity. TNNN Conference 2024
Conference poster

Hanssen, Katrine Sjaastad; Klausen, Kasper; Tomren, Åste Brune; Normann, Amund Stensrud; Sandvig, Axel; Sikorski, Pawel Tadeusz; Sandvig, Ioanna. (2024) Advanced Interfaces for Investigating the Impact of Topology on the Functional Dynamics of Engineered Neural Networks. TNNN Conference 2024
Conference lecture

Sandvig, Ioanna. (2024) Brain subregion-specific microcircuits as models of Alzheimer´s disease. The Limbic Structures of the Brain. From bench to Bedside - Summer School
Conference lecture

Hanssen, Katrine Sjaastad; Klausen, Kasper; Tomren, Åste Brune; Normann, Amund Stensrud; Sandvig, Axel; Sikorski, Pawel Tadeusz; Sandvig, Ioanna. (2024) Advanced Interfaces for Investigating the Impact of Topology on the Functional Dynamics of Engineered Neural Networks. 4th In-Vitro 2D & 3D Neuronal Networks Summit
Conference poster

Kollstrøm, Anna Mikalsen; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2024) Longitudinal assessment of ALS patient-derived motor neuron networks reveals structural and functional impairments. Nordic Neuroscience Meeting 2024
Conference poster

Fiskum, Vegard; Winter-Hjelm, Nicolai; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2024) Deciphering micro-and mesoscale dynamics in ALS patient-derived motor neuron networks. 4th Nordic Neuroscience Meeting
Conference lecture

Winter-Hjelm, Nicolai; Sandvig, Axel; Sikorski, Pawel; Sandvig, Ioanna. (2024) Engineered Cortical Microcircuits for Investigations of Neuroplasticity. TNNN Conference 2024
Conference poster

Winter-Hjelm, Nicolai; Hanssen, Katrine Sjaastad; Klausen, Kasper; Tomren, Åste Brune; Normann, Amund Stensrud; Sandvig, Axel; Sikorski, Pawel; Sandvig, Ioanna. (2024) Advanced Interfaces for Investigating the Impact of Topology on the Functional Dynamics of Engineered Neural Networks. Nordic NanoLab User Meeting 2024
Conference poster

Grønlie, Marthe Bendiksvoll; Kollstrøm, Anna Mikalsen; Christiansen, Nicholas; Røberg, Mari Susanne Ås; Sandvig, Axel; Sandvig, Ioanna. (2024) Advanced Cellular Models of Neurodegenerative Disease: Early Alterations in Neuronal Network Activity. National PhD Conference in Neuroscience 2024

2023

Conference poster

Hanssen, Katrine Sjaastad; Winter-Hjelm, Nicolai; Niethammer, Salome Nora; Witter, Menno Peter; Kobro-Flatmoen, Asgeir; Sandvig, Axel; Sandvig, Ioanna. (2023) An in vitro platform to study entorhinal-hippocampal neuronal networks. 17th International Conference on Alzheimer’s & Parkinson’s Diseases (AD/PD)
Conference lecture

Hanssen, Katrine Sjaastad; Winter-Hjelm, Nicolai; Niethammer, Salome Nora; Witter, Menno Peter; Kobro-Flatmoen, Asgeir; Sandvig, Axel; Sandvig, Ioanna. (2023) Reverse Engineering of Feedforward Cortical-Hippocampal Neural Networks Relevant for Preclinical Disease Modelling . 10th Annual PhD Conference in Neuroscience
Conference lecture

Winter-Hjelm, Nicolai; Klausen, Kasper Grøndahl; Normann, Amund Stensrud; Sandvig, Axel; Sandvig, Ioanna; Sikorski, Pawel. (2023) Novel 3D Interfaces with Embedded Nanoporous Microelectrodes for Preclinical Neuroscience Research. TNNN Conference 2023
Conference poster

Winter-Hjelm, Nicolai; Hanssen, Katrine Sjaastad; Tomren, Åste Brune; Sikorski, Pawel; Sandvig, Axel; Sandvig, Ioanna. (2023) Engineered Multi-Nodal Neuronal Networks with Predefined Afferent-Efferent Connectivity for Advanced Modelling of Network Function and Dysfunction. 14th EBSA Congress
Conference lecture

Winter-Hjelm, Nicolai; Klausen, Kasper Grøndahl; Normann, Amund Stensrud; Sandvig, Axel; Sandvig, Ioanna; Sikorski, Pawel. (2023) Novel 3D Interfaces for Enhancing the Electrophysiological Complexity of Engineered Neuronal Networks. Norwegian Research School for Neuroscience 10th NRSN Conference
Conference poster

Øvreeide, Ingrid Haga; Szydlak, Renata; Zemla, Joanna; Luty, Marcin; Monaldi, Jessica; Hines, Thomas G.; Zielinski, Tomasz; Prot, Victorien Emile; Lekka, Małgorzata; Winter-Hjelm, Nicolai. (2023) Micro- and nanofabrication for biophysics and biomedical research. Sensor Day
Conference lecture

Winter-Hjelm, Nicolai; Hanssen, Katrine Sjaastad; Sikorski, Pawel; Sandvig, Axel; Sandvig, Ioanna. (2023) Advanced Engineering Approaches for Recapitulating Structure-Function Dynamics of Neuronal Networks In Vitro. NeuroSYS 2023
Conference lecture

Hanssen, Katrine Sjaastad; Winter-Hjelm, Nicolai; Niethammer, Salome Nora; Kobro-Flatmoen, Asgeir; Witter, Menno Peter; Sandvig, Axel; Sandvig, Ioanna. (2023) Reverse Engineering of Feedforward Cortical-Hippocampal Neural Networks Relevant for Preclinical Disease Modelling. NRSN Norwegian Research School for Neuroscience 10th NRSN Conference

2022

Conference poster

Heiney, Kristine Anne; Ramstad, Ola Huse; Fiskum, Vegard; Sandvig, Axel; Sandvig, Ioanna; Nichele, Stefano. (2022) Neuronal avalanche dynamics and functional connectivity as indicators of the computational capacity of in vitro neuronal networks. FENS Summer School on "Artificial and natural computations for sensory perception: what is the link?"
Conference poster

Hanssen, Katrine Sjaastad; Sandvig, Ioanna; Sandvig, Axel; Witter, Menno; Kobro-Flatmoen, Asgeir. (2022) An in vitro platform to study adult entorhinal networks in Alzheimer's disease. AD/PD 2022
Conference poster

Kollstrøm, Anna Mikalsen; Sandvig, Ioanna; Sandvig, Axel. (2022) Effects of early-onset ALS pathology on neural network dynamics. FENS Forum 2022
Conference lecture

Winter-Hjelm, Nicolai; Sikorski, Pawel; Sandvig, Axel; Sandvig, Ioanna. (2022) Advanced Engineering Approaches for Recapitulation of Structure-Function Dynamics in Neuronal Networks. TNNN
Conference lecture

Hanssen, Katrine Sjaastad; Winter-Hjelm, Nicolai; Sandvig, Axel; Witter, Menno; Kobro-Flatmoen, Asgeir; Sandvig, Ioanna. (2022) An in vitro platform to study entorhinal-hippocampal neural networks. 9th NRSN Conference
Conference poster

Hanssen, Katrine Sjaastad; Winter-Hjelm, Nicolai; Sandvig, Axel; Witter, Menno; Kobro-Flatmoen, Asgeir; Sandvig, Ioanna. (2022) An in vitro platform to study adult entorhinal entorhinal-hippocampal neuronal circuits in early Alzheimer's disease. JANUBET Symposiym
Conference poster

Winter-Hjelm, Nicolai; Tomren, Åste Brune; Sikorski, Pawel; Sandvig, Axel; Sandvig, Ioanna. (2022) Advanced Engineering Approaches for Recapitulation of Structure-Function Dynamics in Neural Networks. 9th NRSN Conference
Conference poster

Winter-Hjelm, Nicolai; Sikorski, Pawel; Sandvig, Axel; Sandvig, Ioanna. (2022) Advanced Engineering Approaches for Recapitulation of Structure-Function Dynamics in Neuronal Networks. FENS Forum 2022
Conference lecture

Winter-Hjelm, Nicolai; Sikorski, Pawel; Sandvig, Axel; Sandvig, Ioanna. (2022) Advancing the Frontier of Neuroscience with Engineered Neural Networks. NTNU Nano Lecture
Conference poster

Winter-Hjelm, Nicolai; Sikorski, Pawel; Sandvig, Axel; Sandvig, Ioanna. (2022) Next-Generation Microfluidics Interfaced with Microelectrode Arrays for Neuroscience Applications. Nordic NanoLab User Meeting
Conference poster

Kollstrøm, Anna Mikalsen; Sandvig, Ioanna; Sandvig, Axel. (2022) Effects of early-onset ALS pathology on neural network dynamics. NRSN National PhD Conference in Neuroscience 2022
Conference poster

Bjorkli, Christiana; Ebbesen, Nora Cecilie; Nair, Rajeevkumar Raveendran; Julian, Joshua Benjamin; Weir, Janelle Shari; Witter, Menno; Sandvig, Axel; Sandvig, Ioanna. (2022) A switch for Alzheimer's disease neuropathology at its regional origin. AD/PD
Conference poster

Bjorkli, Christiana; Hemler, Mary Elisabeth; Julian, Joshua Benjamin; Sandvig, Axel; Sandvig, Ioanna. (2022) Using intracerebral microdialysis to probe the pharmacokinetics of Alzheimer's disease drug candidates. AD/PD

2021

Interview

Oakes, kelly; Sandvig, Ioanna. (2021) Researchers at NTNU are studying brain cells in the lab to investigate the foggy beginnings of diseases like Parkinson’s and Alzheimer’s.
Conference lecture

Sandvig, Ioanna. (2021) Recapitulation of complex neural network dynamics underlying physiological behaviours and pathological alterations. NRSN National Neuroscience Symposium
Conference lecture

Heiney, Kristine; Ramstad, Ola Huse; Fiskum, Vegard; Sandvig, Axel; Sandvig, Ioanna; Nichele, Stefano. (2021) From in vitro to computational models of the brain: What can criticality tell us about neural computation?. NRSN National Neuroscience Symposium
Conference lecture

Winter-Hjelm, Nicolai; Sikorski, Pawel; Sandvig, Axel; Sandvig, Ioanna. (2021) Controlling the Flow of Information in Neuronal Networks Through the use of Customized Microfluidics. Norwegian NanoSymposium 2021
Conference lecture

Winter-Hjelm, Nicolai; Sikorski, Pawel; Sandvig, Axel; Sandvig, Ioanna. (2021) Engineered Neural Networks as Computational Substrates. NTNU NanoLab Lunch Talk
Conference poster

Schiro, Lars Erik; Bauer, Ulrich Stefan; Sandvig, Axel; Sandvig, Ioanna. (2021) Neurogenic niche activation and contribution to the reorganization of local neural networks in response to traumatic central nervous system injury. NRSN National Neuroscience Symposium 2021
Conference poster

Kollstrøm, Anna Mikalsen; Sandvig, Ioanna; Sandvig, Axel. (2021) Decoding motor neuron vulnerability and connectivity in ALS. NRSN National Neuroscience Symposium
Conference poster

Christiansen, Nicholas; Sandvig, Ioanna; Sandvig, Axel. (2021) A biologically plausible axon growth model to study changes in neural network function in healthy and perturbed conditions. NRSN National Neuroscience Symposium 2021
Conference poster

Fiskum, Vegard; Sandvig, Axel; Sandvig, Ioanna. (2021) Hypoxia as a model of neural network perturbation and the effect of global inhibition on neural network functionality. NRSN National Neuroscience Symposium 2021
Conference poster

Weir, Janelle Shari; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2021) The DREADDed in-vitro neuronal network: How structure and function inform computational efficiency. NRSN National Neuroscience Symposium
Conference poster

Hanssen, Katrine Sjaastad; Sandvig, Ioanna; Sandvig, Axel; Witter, Menno; Kobro-Flatmoen, Asgeir. (2021) An in vitro platform to study entorhinal networks in Alzheimer’s disease. NRSN National Neuroscience Symposium
Conference poster

Winter-Hjelm, Nicolai; Sikorski, Pawel; Sandvig, Axel; Sandvig, Ioanna. (2021) Engineered Neural Networks as Computational Substrates. NRSN National Neuroscience Symposium 2021
Conference poster

Bjorkli, Christiana; Hemler, Mary Elisabeth; Ebbessen, Nora Cecilie; Nair, Rajeevkumar Raveendran; Kobro-Flatmoen, Asgeir; Witter, Menno; Sandvig, Axel; Sandvig, Ioanna. (2021) Linking molecular biomarkers and behavior in rodent models and patients with Alzheimer’s disease. NRSN National Neuroscience Symposium
Conference poster

Bjorkli, Christiana; Hemler, Mary Elisabeth; Witter, Menno; Kobro-Flatmoen, Asgeir; Sandvig, Axel; Sandvig, Ioanna. (2021) Linking molecular biomarkers and behavior in rodents and patients with Alzheimer’s disease. The Lancet Summit: Presymptomatic Prevention and Treatment of Neurodegenerative Diseases
Conference poster

Bjorkli, Christiana; Hemler, Mary Elisabeth; Ebbesen, Nora Cecilie; Witter, Menno; Nair, Rajeevkumar Raveendran; Kobro-Flatmoen, Asgeir; Sandvig, Axel; Sandvig, Ioanna. (2021) Linking molecular biomarkers and behavior in rodents and patients with Alzheimer’s disease. AD/PD
Conference poster

Bjorkli, Christiana; Hemler, Mary Elisabeth; Ebbesen, Nora Cecilie; Nair, Rajeevkumar Raveendran; Witter, Menno; Kentros, Clifford; Kobro-Flatmoen, Asgeir; Sandvig, Axel; Sandvig, Ioanna. (2021) Linking molecular biomarkers and behavior in preclinical models and patients with Alzheimer's disease. SfN Global Connectome

2020

Lecture

Sandvig, Ioanna. (2020) Neuron- and network specific models of Alzheimer´s disease. 1st NO AD Network Meeting
Conference poster

Hanssen, Katrine Sjaastad; Kobro-Flatmoen, Asgeir; Sandvig, Ioanna; Sandvig, Axel; Witter, Menno. (2020) Developing a novel in vitro platform to study neuronal networks relevant to Alzheimer’s disease. FENS Forum 2020
Conference poster

Christiansen, Nicholas; Sandvig, Ioanna; Sandvig, Axel. (2020) Using computer models to elucidate the underlying mechanisms and effects of disease pathology of amyotrophic lateral sclerosis on network function. FENS Virtual Forum 2020
Conference poster

Fiskum, Vegard; Sandvig, Axel; Sandvig, Ioanna. (2020) Hypoxia as a model of neuronal network insult and the effect of global inhibition on neuronal network functionality. FENS Virtual Forum 2020
Conference poster

Bjorkli, Christiana; Hemler, MB; Raveendran Nair, Rajeevkumar; Kobro-Flatmoen, Asgeir; Witter, Menno; Kentros, Clifford; Sandvig, Axel; Sandvig, Ioanna. (2020) Linking molecular biomarkers and behavior in rodents and patients with Alzheimer’s disease. FENS Virtual Forum 2020
Conference lecture

Pontes-Filho, Sidney; Lind, Pedro; Yazidi, Anis; Zhang, Jianhua; Hammer, Hugo Lewi; Mello, Gustavo; Sandvig, Ioanna; Tufte, Gunnar; Nichele, Stefano. (2020) EvoDynamic: A Framework for the Evolution of Generally Represented Dynamical Systems and Its Application to Criticality. 23rd European Conference on the Applications of Evolutionary and bio-inspired Computation
Conference poster

Heiney, Kristine; Ramstad, Ola Huse; Sandvig, Axel; Sandvig, Ioanna; Nichele, Stefano. (2020) Manipulating the dynamic state of in vitro neuronal networks. Brain Criticality Virtual Meeting
Conference poster

Weir, Janelle Shari; Christiansen, Nicholas; Nichele, Stefano; Lind, Pedro; Sandvig, Axel; Sandvig, Ioanna. (2020) From topology to functionality: Does perturbation in in-vitro neural networks drive hub adaptation towards computational efficiency?. FENS Forum 2020
Conference poster

Heiney, Kristine; Ramstad, Ola Huse; Fiskum, Vegard; Sandvig, Axel; Sandvig, Ioanna; Nichele, Stefano. (2020) Manipulation of the scaling behavior of neuronal avalanches toward achieving criticality. FENS 2020 Virtual Forum
Conference poster

Bjorkli, Christiana; Hemler, Mary Elisabeth; Nair, Rajeevkumar Raveendran; Witter, Menno; Sandvig, Ioanna; Sandvig, Axel. (2020) Linking molecular biomarkers and behavior in rodents and patients with Alzheimer’s disease. Cold Spring Harbor meeting: Neurodegenerative Diseases: Biology & Therapeutics
Conference poster

Heiney, Kristine; Ramstad, Ola Huse; Fiskum, Vegard; Sandvig, Ioanna; Sandvig, Axel; Nichele, Stefano. (2020) Computational behavior of biological neural networks through the lens of criticality. NAISys - From Neuroscience to Artificially Intelligent Systems

2019

Conference lecture

Sandvig, Ioanna. (2019) Connectomics of engineered neural networks: inferring network states and making predictions about responses to stroke-related pathology. Mini-Symposium BMC University of Lund
Conference poster

Christiansen, Nicholas; Nichele, Stefano; Tufte, Gunnar; Sandvig, Ioanna; Sandvig, Axel. (2019) Using computer models to infer disease pathology in in vitro models of amyotrophic lateral sclerosis. The 7th National PhD Conference in Neuroscience
Conference lecture

Kobro-Flatmoen, Asgeir; Sandvig, Axel; Sandvig, Ioanna; Witter, Menno Peter. (2019) Developing a novel in vitro platform to study Alzheimer’s disease-relevant neuronal networks. Alzheimer's Disease Seminar Series (AD Seminar)
Conference poster

Bjorkli, Christiana; Sandvig, Ioanna; Sandvig, Axel; Kentros, Clifford; Witter, Menno; Kobro-Flatmoen, Asgeir. (2019) Linking molecular biomarkers and behaviour in animal models and humans with Alzheimer´s disease. 3rd Nordic Neuroscience Meeting
Conference poster

Weir, Janelle Shari; Sandvig, Axel; Sandvig, Ioanna; Nichele, Stefano. (2019) In vitro neural networks as self-organizing computational substrates. The 7th NRSN National PhD Conference in Neuroscience
Conference poster

Hanssen, Katrine Sjaastad; Kobro-Flatmoen, Asgeir; Sandvig, Ioanna; Sandvig, Axel; Witter, Menno. (2019) Establishing entorhinal cortex layer II neuron cultures as a tool for the investigation of early Alzheimer's disease related changes. 3rd Nordic Neuroscience Meeting 2019
Conference lecture

Mello, Gustavo Borges Moreno E; Valderhaug, Vibeke Devold; Pontes-Filho, Sidney; Zouganeli, Evi; Ramstad, Ola Huse; Sandvig, Axel; Sandvig, Ioanna; Nichele, Stefano. (2019) Method to obtain neuromorphic reservoir networks from images of in vitro cortical networks. 2019 IEEE Symposium Series on Computational Intelligence: IEEE Symposium on Neuromorphic Cognitive Computing (IEEE SNCC)
Conference poster

Christiansen, Nicholas; Nichele, Stefano; Tufte, Gunnar; Sandvig, Ioanna; Sandvig, Axel. (2019) Using computer models to infer disease pathology in in vitro models of amyotrophic lateral sclerosis. 3rd Nordic Neuroscience Meeting
Conference poster

Ramstad, Ola Huse; van de Wijdeven, Rosanne Francisca; Heiney, Kristine; Nichele, Stefano; Sandvig, Ioanna; Sandvig, Axel. (2019) Mapping functional response to axotomy in a reductionist corticospinal network. 3rd Nordic neuroscience Meeting
Conference poster

Bauer, Ulrich Stefan; van de Wijdeven, Rosanne Francisca; Raveendran Nair, Rajeevkumar; Sandvig, Ioanna; Sandvig, Axel. (2019) Developing an engineered neural network model to use in the study of amyotrophic lateral sclerosis. 3rd Nordic Neuroscience Meeting
Conference poster

Weir, Janelle Shari; Valderhaug, Vibeke Devold; Sandvig, Axel; Sandvig, Ioanna. (2019) Structural and functional dynamics of healthy and perturbed neural networks in vitro. 3rd Nordic neuroscience Meeting
Conference poster

Schiro, Lars Erik; Bauer, Ulrich Stefan; Tufte, Gunnar; Sandvig, Axel; Sandvig, Ioanna. (2019) Alterations in functional spinal cord circuitry in response to injury. 3rd Nordic Neuroscience Meeting
Conference poster

Heiney, Kristine; Valderhaug, Vibeke Devold; Sandvig, Ioanna; Tufte, Gunnar; Hammer, Hugo Lewi; Nichele, Stefano. (2019) Evaluating the criticality of neuronal networks toward the identification of pathological conditions. 3rd Nordic Neuroscience Meeting
Conference poster

Valderhaug, Vibeke Devold; van de Wijdeven, Rosanne; Ramstad, Ola Huse; Sandvig, Axel; Sandvig, Ioanna. (2019) Micro- and mesoscale dynamics of engineered neural networks in response to Parkinson´s related pathology. 55th Contact Meeting of the Norwegian Biochemical Society
Conference lecture

Heiney, Kristine; Valderhaug, Vibeke Devold; Ramstad, Ola Huse; Sandvig, Ioanna; Sandvig, Axel; Tufte, Gunnar; Hammer, Hugo Lewi; Nichele, Stefano. (2019) Evaluation of the criticality of in vitro neuronal networks: Toward an assessment of computational capacity. IEEE ICDL-EpiRob 2019 - Workshop on Novel Substrates and Models for the Emergence of Developmental, Learning and Cognitive Capabilities
Conference poster

Ramstad, Ola Huse; Wijdeven, Rosanne Francisca van de; Heiney, Kristine; Nichele, Stefano; Sandvig, Ioanna; Sandvig, Axel. (2019) Mapping functional response to axotomy in a reductionist corticospinal circuit. NRSN PhD conference
Conference lecture

Heiney, Kristine; Ramstad, Ola Huse; Sandvig, Ioanna; Sandvig, Axel; Nichele, Stefano. (2019) Assessment and manipulation of the computational capacity of in vitro neuronal networks through criticality in neuronal avalanches. IEEE Symposium Series on Computational Intelligence: Symposium on Artificial Life
Conference lecture

Sandvig, Ioanna. (2019) Introduction to the Translational Neuroscience Clinical-Academic Research Group (CARG), NTNU/St Olav. AD Seminar series
Conference lecture

Sandvig, Ioanna. (2019) Micro- and mesoscale connectomics of in vitro neural networks Inferring network states and making predictions about responses to lesion-related pathology. Seminar GIGA Institute
Conference lecture

Sandvig, Ioanna. (2019) Micro- and mesoscale dynamics of engineered neural networks in response to Parkinson´s related pathology. 55th Contact Meeting of the Norwegian Biochemical Society
Conference lecture

Sandvig, Ioanna. (2019) Micro- and mesoscale connectomics of healthy and perturbed in vitro neural networks . Seminar, Institute of Neuroscience, UC Louvain
Feature article

Glover, Joel; Tysnes, Ole-Bjørn; Myhr, Kjell-Morten; Bråthen, Geir; Sandvig, Ioanna; Høyer, Helle; Holmøy, Trygve; Nakken, Ola; Harbo, Hanne Flinstad. (2019) Hvor står ALS-forskningen i Norge?.
Conference poster

Weir, Janelle Shari; Sandvig, Axel; Sandvig, Ioanna. (2019) Investigation of neuroplasticity mechanisms of in vitro neural networks. The 3rd Nordic Neuroscience Meeting
Conference lecture

Heiney, Kristine; Ramstad, Ola Huse; Sandvig, Ioanna; Sandvig, Axel; Nichele, Stefano. (2019) Assessment and manipulation of the computational capacity of in vitro neuronal networks through criticality in neuronal avalanches. 7th NRSN PhD Conference

2018

Conference poster

Valderhaug, Vibeke Devold; Ramstad, Ola Huse; Wijdeven, Rosanne Francisca van de; Mcdonagh, Birgitte Hjelmeland; Knudsen, Martinius; Kuan, Wi-Li; Sandvig, Axel; Sandvig, Ioanna. (2018) Deciphering the neural network response to Parkinson's disease associated proteinopathy. FENS Forum
Conference lecture

Sandvig, Ioanna. (2018) Engineeered neural networks as self-organised computational substrates in the healthy and lesioned CNS. Brain Repair Centre Seminar Series, University of Cambridge
Conference poster

van de Wijdeven, Rosanne; Ramstad, Ola Huse; Bauer, Ulrich Stefan; Halaas, Øyvind; Sandvig, Axel; Sandvig, Ioanna. (2018) An open microfluidic chip for the application of structuring 2D and 3D neural networks. FENS Forum
Conference poster

Ramstad, Ola Huse; Jarlsdottir, Sigrun; Wijdeven, Rosanne Francisca van de; Tufte, Gunnar; Sandvig, Ioanna; Sandvig, Axel. (2018) Investigating the effect of axotomy on motoneuron network dynamics. FENS 2018
Lecture

Sandvig, Ioanna. (2018) Modelling morphology-activity relationships in healthy and perturbed neural networks. MH, NTNU - Exchange visit from San Donato Hospital Group
Conference lecture

Sandvig, Ioanna. (2018) Neuroplasticity in stroke recovery. How inflammatory processes engage and modify synapses and networks. Kavli Institute for Systems Neuroscience, AD Seminar Series
Conference lecture

Bauer, Ulrich Stefan; van de Wijdeven, Rosanne; Sandvig, Ioanna; Sandvig, Axel. (2018) A Functional Neuromuscular Unit in a Reproducible Structured Culture for Study of Amyotrophic Lateral Sclerosis. 6th NRSN PhD Conference
Conference poster

Bauer, Ulrich Stefan; van de Wijdeven, Rosanne; Sandvig, Ioanna; Sandvig, Axel. (2018) Studying Amyotrophic Lateral Sclerosis on Functional Neuromuscular Units Containing Subcomponents in Distinct Microenvironments. 11th FENS Forum of Neuroscience
Lecture

Sandvig, Ioanna. (2018) Engineered neural networks as self-organising computational substrates modelling CNS function, damage, and repair. University of Patras Lecture Series
Conference poster

Fiskum, Vegard; Nichele, Stefano; Sandvig, Ioanna; Sandvig, Axel. (2018) Modelling neural network dynamics in amyotrophic lateral sclerosis (ALS). NRSN 6th Annual PhD conference in Neuroscience
Conference poster

Ramstad, Ola Huse; Jarlsdottir, Sigrun; Wijdeven, Rosanne Francisca van de; Tufte, Gunnar; Sandvig, Ioanna; Sandvig, Axel. (2018) Investigating the effect of axotomy on motoneuron networks. Norwegian School of Neuroscience PhD conference

2017

Conference lecture

Sandvig, Ioanna. (2017) Understanding adaptive and maladaptive neural network plasticity in vitro and in silico. Second Christmas Workshop on CNS Function, Damage, and Repair
Interview

Wetlesen, Karin Johanne; Tufte, Gunnar; Nichele, Stefano; Sandvig, Ioanna; Stavdahl, Øyvind. (2017) Roboter med menneskelige hjerneceller er ikke lenger bare fantasi fra sience fiction.
Conference poster

Augestad, Ingrid Lovise; Valderhaug, Vibeke Devold; Sandvig, Axel; Håberg, Asta; Sandvig, Ioanna. (2017) Modulation of the inflammatory response after transient cerebral ischemia in rats through minocycline treatment combined with human neural stem cell implantation. . Nordic Neuroscience 2017
Lecture

Sandvig, Ioanna; Tufte, Gunnar. (2017) Robotics - The NTNU Cyborg fusing neuroscience and automation. Statoil's CIUS day
Lecture

Sandvig, Ioanna. (2017) In vitro neural networks. Workshop MESA+
Conference poster

Bauer, Ulrich Stefan; van de Wijdeven, Rosanne; Ramstad, Ola Huse; Tufte, Gunnar; Nichele, Stefano; Sandvig, Ioanna; Sandvig, Axel. (2017) Developing an engineered neural network model to use in the study of Amyotrophic Lateral Sclerosis (ALS). 5th NRSN PhD Conference
Interview

Wolden, Grete; Brandslet, Steinar; Nichele, Stefano; Tufte, Gunnar; Aaser, Peter; Knudsen, Martinius; Hendseth, Sverre; Sandvig, Ioanna; Ramstad, Ola Huse; van de Wijdeven, Rosanne. (2017) I, Cyborg.
Conference poster

Bauer, Ulrich Stefan; Ramstad, Ola Huse; Tufte, Gunnar; Nichele, Stefano; Sandvig, Ioanna; Sandvig, Axel. (2017) Developing an Engineered Neural Network Model for the Study of ALS. Nordic Neuroscience 2017
Interview

Wolden, Grete; Nichele, Stefano; Tufte, Gunnar; Aaser, Peter; Knudsen, Martinius; Hendseth, Sverre; Sandvig, Ioanna; Ramstad, Ola Huse; van de Wijdeven, Rosanne; Åm, Heidrun. (2017) Denne roboten blir styrt av levende hjerneceller.
Interview

Joakimsen, Trygve Strand; Lystad, Malin Sveinsdotter; Nichele, Stefano; Tufte, Gunnar; Aaser, Peter; Knudsen, Martinius; Hendseth, Sverre; Sandvig, Ioanna; Ramstad, Ola Huse; van de Wijdeven, Rosanne. (2017) Lager krysning mellom menneske og maskin.
Interview

Meland, Svein Inge; Nichele, Stefano; Tufte, Gunnar; Aaser, Peter; Knudsen, Martinius; Hendseth, Sverre; Sandvig, Ioanna; Ramstad, Ola Huse; van de Wijdeven, Rosanne; Åm, Heidrun. (2017) NTNU skal lage en ekte Kyborg.
Interview

Wolden, Grete; Brandslet, Steinar; Nichele, Stefano; Tufte, Gunnar; Aaser, Peter; Knudsen, Martinius; Hendseth, Sverre; Sandvig, Ioanna; Ramstad, Ola Huse; van de Wijdeven, Rosanne. (2017) Forskere ved NTNU utvikler en robot som skal styres av levende hjerneceller.
Interview

Wolden, Grete; Brandslet, Steinar; Nichele, Stefano; Tufte, Gunnar; Aaser, Peter; Knudsen, Martinius; Hendseth, Sverre; Sandvig, Ioanna; Ramstad, Ola Huse; van de Wijdeven, Rosanne. (2017) Jeg, Kyborg.
Lecture

Sandvig, Ioanna. (2017) Promoting brain repair after cerebral ischemia. What can we learn from experimental models?. Onsdagsmøte GeMS, INB
Conference poster

van de Wijdeven, Rosanne; Ramstad, Ola Huse; Valderhaug, Vibeke Devold; Halaas, Øyvind; Sandvig, Axel; Sandvig, Ioanna. (2017) A multi-nodal microfluidic chip for structuring neural networks in vitro. NRSN PhD conference
Conference lecture

Sandvig, Ioanna. (2017) Morphology-activity relationships in motor neurone networks. Hjernehelse – Fra Forskning til Klinisk Praksis, Hjerneforskning i pasientautonomiens tid
Conference poster

Valderhaug, Vibeke Devold; Ramstad, Ola Huse; van de Wijdeven, Rosanne; Kuan, Wi-Li; Sandvig, Axel; Sandvig, Ioanna. (2017) Engineered dopaminergic neuron networks in the study of Parkinson's disease mechanisms. Nordic Neuroscience 2017
Conference poster

Ramstad, Ola Huse; Sandvig, Ioanna; Nichele, Stefano; Tufte, Gunnar; Sandvig, Axel. (2017) Modelling dynamics of motoneuron networks and spinal cord injury in vitro. Nordic Neuroscience 2017

2016

Conference lecture

Sandvig, Ioanna. (2016) In situ tissue engineering strategies for stroke repair. 18th International Neuroscience Winter Conference
Conference lecture

Sandvig, Ioanna. (2016) Revisiting a central question: How we may be able to repair the damaged CNS. SfN Chapter at Kavli Institute for Systems Neuroscience/Centre for Neural Computation
Conference poster

Augestad, Ingrid Lovise; Valderhaug, Vibeke Devold; Sandvig, Axel; Håberg, Asta; Sandvig, Ioanna. (2016) Effects of Minocycline treatment on human neural stem cell survival and microglial response after focal transient cerebral ischemia in adult rats. The 4th National PhD Conference in Neuroscience
Conference poster

van de Wijdeven, Rosanne; Ramstad, Ola Huse; Sandvig, Axel; Sandvig, Ioanna; Halaas, Øyvind. (2016) Spontaneous neural stem cell differentiation in a microfluidic chip. FENS Forum 2016
Lecture

Sandvig, Ioanna; Sandvig, Axel. (2016) Towards harnessing brain plasticity via closed-loop neural interfaces. 1st Christmas Workshop on CNS Function, Damage and Repair
Conference lecture

Sandvig, Ioanna. (2016) Dust-size neural implants. Cyborg winter seminar
Lecture

Sandvig, Ioanna. (2016) Therapeutic interventions for stroke and spinal cord injury: clinical perspective. Stroke and spinal cord injury repair
Contribution to radio or TV

Tarjem, Guro; Stavdahl, Øyvind; Knudsen, Martinius; Nichele, Stefano; Tufte, Gunnar; Ramstad, Ola Huse; Sandvig, Ioanna. (2016) Norsk robot får hjerneceller fra mennesker.
Lecture

van de Wijdeven, Rosanne; Ramstad, Ola Huse; Sandvig, Ioanna; Sandvig, Axel; Halaas, Øyvind. (2016) Structuring modular neuronal networks in a compartmentalized microenvironment. National PhD conference NRSN
Conference poster

van de Wijdeven, Rosanne; Ramstad, Ola Huse; Sandvig, Ioanna; Sandvig, Axel; Halaas, Øyvind. (2016) Structuring modular neuronal networks in a compartmentalized microenvironment. 7th annual Nanonetwork workshop
Conference lecture

Dalheim, Marianne Øksnes; Vanacker, Julie; Sandvig, Ioanna; Aachmann, Finn Lillelund; Skjåk-Bræk, Gudmund; Christensen, Bjørn E.; Strand, Berit Løkensgard. (2016) Functionalization of alginate for tissue engineering applications. 9th meeting of the Scandinavian Society for Biomaterials
Conference poster

Valderhaug, Vibeke Devold; Bråthen, Geir; Barker, Roger A.; Sandvig, Axel; Sandvig, Ioanna. (2016) Development of personalized cell-based therapies for the treatment of Parkinson´s disease patients. The 4th National PhD Conference in Neuroscience
Lecture

Sandvig, Ioanna. (2016) Innledning: The Common Sense: Teknologi og Etikk - Hvor går grensene?. Forskningsdagene/Trondheim Kunstmuseum Seminar om teknologi, identitet og etikk. Melanie Gilligan: The Common Sense

2015

Conference poster

Nylander, Markus; Sandvig, Ioanna; Sandvig, Axel. (2015) Investigation of hemicraniectomies in patients with malignant stroke and traumatic brain injuries – a retrospective cohort study. 22nd Annual Conference of the American Society for Neural Therapy and Repair
Conference lecture

Augestad, Ingrid Lovise; Nyman, Axel Karl Gottfrid; Widerøe, Marius; Sandvig, Axel; Håberg, Asta; Sandvig, Ioanna. (2015) Anatomical, cellular and structural effects of neural stem cell and/or olfactory ensheathing cell grafts in a rat model of focal cerebral ischemia with reperfusion. 22nd Annual Conference of the American Society of Neural Therapy and Repair
Conference poster

Mcdonagh, Birgitte Hjelmeland; Singh, Gurvinder; Hak, Sjoerd; Bandyopadhyay, Sulalit; Augestad, Ingrid Lovise; Sandvig, Ioanna; Sandvig, Axel; Glomm, Wilhelm. (2015) L-DOPA-coated manganese oxide nanoparticles as dual MRI contrast agents and potential drug delivery vehicles. Nordic Neuroscience 2015
Conference lecture

Sandvig, Ioanna. (2015) Cell replacement therapy in Parkinson’s disease. STEM CELLS – Therapeutic Outlook for Central Nervous System Disorders
Conference poster

Nyman, Axel Karl Gottfrid; Augestad, Ingrid Lovise; Widerøe, Marius; Sandvig, Axel; Håberg, Asta; Sandvig, Ioanna. (2015) Cellular, anatomical, and functional effects of neural stem cell and olfactory ensheathing cell co-grafts in a rat model of transient cerebral ischemia. Nordic Neuroscience 2015

2014

Conference lecture

Sandvig, Ioanna. (2014) In situ tissue engineering for cell transplantation in Parkinson's disease. UK Regenerative Medicine Platform Hub
Interview

Sandvig, Ioanna. (2014) Menneskelig mikrobrikke kan revolusjonere dyreforsøksverden.
Conference poster

Augestad, Ingrid Lovise; Willner, Nadine; Hill, Deborah Kathrine; Sandvig, Axel; Håberg, Asta; Sandvig, Ioanna. (2014) The effects of minocycline on the survival and functional outcome of neural stem cell grafts in experimental stroke. IBRO-PERC Meeting 'New trends in CNS regeneration and treatment'
Lecture

Sandvig, Ioanna. (2014) Cell therapy in the treatment of stroke. IBRO-PERC Meeting 'New Trends in CNS Regeneration and Treatment'
Conference lecture

Sandvig, Ioanna. (2014) Regenerative Medicine: Advances in Stem Cell Technologies and Implications for CNS Repair. Fredagsforelesning St Olav's
Lecture

Nyman, Axel Karl Gottfrid; Sandvig, Ioanna; Widerøe, Marius. (2014) In vivo visualization of stem cell therapy in the hypoxic-ischemic neonatal brain using MRI. Frampeik 2014 - legestudentenes forskningskonferanse
Conference poster

Nyman, Axel Karl Gottfrid; Sandvig, Ioanna; Widerøe, Marius. (2014) In vivo visualisation of stem cell therapy in the hypoxic-ischemic neonatal brain using MRI. Norwegian Research School in Neuroscience Annual Meeting
Lecture

Augestad, Ingrid Lovise; Willner, Nadine; Sandvig, Axel; Håberg, Asta; Sandvig, Ioanna. (2014) Combinatory treatment of experimental ischemic stroke using induced pluripotent stem cells and the neuroprotective/anti-inflammatory agent Minocycline. Norwegian Research School in Neuroscience Annual Meeting
Conference lecture

Sandvig, Axel; Sandvig, Ioanna. (2014) 3R i Regenerativ Medisin. Noecopas fagseminar og årsmøte - 3R pris 2014
Interview

Sandvig, Ioanna. (2014) De ti viktigste fra vitenskapen i 2013.
Interview

Sandvig, Ioanna; Sandvig, Axel. (2014) Fikk pris for færre dyreforsøk.
Conference poster

Sandvig, Ioanna; Kuan, Wi-Li. (2014) In situ tissue engineering for cell transplantation in Parkinson's disease. UKRMP Acellular Technologies Hub Annual Science Meeting

2013

Conference lecture

Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Widerøe, Marius; Sandvig, Ioanna; Torp, Sverre Helge; Skranes, Jon; Brubakk, Ann-Mari; Goa, Pål Erik. (2013) Exposure of long-term intermittent hypoxia-hyperoxia in newborn rats: effects on brain development. Pediatric Academic Society
Conference poster

Nyman, Axel Karl Gottfrid; Modo, Mike; Widerøe, Marius; Haraldseth, Olav; Håberg, Asta; Sandvig, Ioanna. (2013) Co-transplantation of neural stem cells and olfactory ensheathing cells in an adult rat stroke model. The 1st National PhD Conference in Neuroscience
Lecture

Sandvig, Ioanna. (2013) Cell-matrix interactions in tailored biopolymer matrices. Lab seminar
Conference poster

McDonagh, Birgitte Hjelmeland; Volden, Sondre; Lystvet, Sina Marie; Singh, Gurvinder; Ese, M-H; Sandvig, Ioanna; Sandvig, Axel; Lindgren, Mikael; Glomm, Wilhelm. (2013) Staining and cytotoxicity of transferrin gold nanoclusters on cancer cells. NorFab user meeting
Conference poster

Bandyopadhyay, Sulalit; Sandvig, Ioanna; Sandvig, Axel; Singh, Gurvinder; Glomm, Wilhelm. (2013) Multifunctional nanoparticles (NPs) for bioimaging. 5th Norwegian PhD Conference in Medical Imaging
Conference poster

Nyman, Axel Karl Gottfrid; Modo, Michel; Sandvig, Axel; Widerøe, Marius; Haraldseth, Olav; Håberg, Asta; Sandvig, Ioanna. (2013) Co-transplantation of neural stem cells and olfactory ensheathing cells in an adult rat stroke model. 5th Norwegian PhD Conference in Medical Imaging
Conference poster

Sandvig, Ioanna; Hoang, Linh; Olsen, Øystein; Berry, Martin; Haraldseth, Olav; Barnett, Susan C; Sandvig, Axel. (2013) Remyelinating and neuroprotective effects of glial cell transplants in the axotomised retinocortical projection. FENS Regional Meeting 2013
Interview

Sandvig, Ioanna. (2013) Dette er de største gjennombruddene i 2013.

2012

Lecture

Singh, Gurvinder; Sandvig, Ioanna; Mørch, Yrr Asbjørg; Glomm, Wilhelm. (2012) Multifunksjonelle nanopartikler skreddersydd til biomedisin. Divisjon for Innovasjon, Forskningrådet
Conference lecture

Sandvig, Ioanna. (2012) Key strategies for in situ tissue engineering and induced neural plasticity in experimental stroke models. Lecture series
Conference lecture

Sandvig, Ioanna. (2012) Induced plasticity and recapitulation of development in the adult CNS. Regenerative Medicine: opportunities and challenges

2011

Interview

Sandvig, Ioanna. (2011) Jakten på hjerneprotesen.
Interview

Sandvig, Ioanna. (2011) Ny hjerne med protese kan bli mulig.
Conference lecture

Sandvig, Ioanna. (2011) MRI and biomaterials in studies of CNS repair mediated by cell transplants. Weekly seminar series
Conference lecture

Sandvig, Ioanna. (2011) Integration of multimodal MRI and biomaterials in experimental models of transplant-mediated CNS repair. KTH Seminar series

2010

Conference poster

Sandvig, Ioanna. (2010) Transplant-mediated CNS repair: intracellular contrast agents, cell tracking by MRI, and tissue engineering. MI Lab Day
Conference lecture

Sandvig, Ioanna. (2010) Imaging transplant-mediated repair in the rat visual system: art, fact, or artefact?. MI Lab Day

2009

Conference lecture

Sandvig, Ioanna. (2009) In vivo tracking of MPIO-labelled glial cells in the rat CNS. Second Nordic Imaging Network Symposium
Conference lecture

Sandvig, Ioanna. (2009) Imaging cell grafts and regenerating axons in a rat CNS injury model. FUGE - Small animal MRI workshop
Conference lecture

Sandvig, Ioanna. (2009) Molecular mechanisms of axon guidance and regeneration. Tuesday lunch and presentation

2008

Conference lecture

Sandvig, Ioanna. (2008) In vivo cell tracking in CNS repair. LKB Seminar
Conference lecture

Sandvig, Ioanna. (2008) Biomaterials in cell transplantation after CNS injury. MI Lab Day
Conference lecture

Sandvig, Ioanna. (2008) In vivo imaging of cell grafts in CNS repair. Meeting with NFR representatives
Conference lecture

Sandvig, Ioanna. (2008) MR Imaging of cells in transplant-mediated CNS repair. Electron Microscopy Microseminar
Conference poster

Brekken, Christian; Sandvig, Ioanna; Haraldseth, Olav; Skjåk-Bræk, Gudmund; Mørch, Yrr Asbjørg. (2008) Manganese-Alginate Gels for Controlled Release of Mn2+. ISMRM

Språkvelger

Ioanna Sandvig

Ioanna Sandvig

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