Karoline Aker
+4799645107
Kvinne-barnsenteret, 241.06.016, Øya, Olav Kyrres gate 11
About
I am a Postdoctoral Fellow at IKOM and my main research interests are neonatology and global health.
I am part of the research group Neonatal medical research - NTNU Neo.
Research
I defended my PhD in May 2022 on the project entitled “Perinatal asphyxia in a global perspective: How can we improve outcomes?” with main supervisor Ragnhild Støen. The first part of my PhD project was a retrospective observational study of incidence and long-term outcomes after perinatal asphyxia in Sør Trøndelag before and after the implementation of therapeutic hypothermia (cooling). The second study was a randomized controlled trial of therapeutic hypothermia for infants with perinatal asphyxia in India (THIN-study). My postdoctoral project is closely related to my PhD with the topic perinatal asphyxia and therapeutic hypothermia. We use national health registries to explore long-term outcomes of neonates recieving therapeutic hypothermia in Norway.
Background
- 2010: Cand.med (MD), NTNU
- 2010-11: Internship at Levanger Hospital
- 2011-12: Internship in Stjørdal kommune
- 2012-18(-22): Resident in pediatrics, Department of Pediatrics, St. Olavs Hospital
- 2015-22: PhD Candidate in Medicine at IKOM, NTNU
- 2018-19: PhD representative in the IKOM leadership group (utvidet ledergruppe)
- 2022-23: Associate Professor, IKOM, NTNU
- 2023- : Postdoctoral Fellow, IKOM, NTNU
Competencies
Publications
2025
-
Kristoffersen, Laila Marie;
Støen, Ragnhild;
Bergseng, Håkon;
Flottorp, Silje Tjøm;
Magerøy, Grete;
Grunewaldt, Kristine Hermansen.
(2025)
Immediate Skin-to-Skin Contact in Very Preterm Neonates and Early Childhood Neurodevelopment: A Randomized Clinical Trial.
JAMA Network Open
Academic article
2024
-
Francke, Karen Haugvik;
Støen, Ragnhild;
Thomas, Niranjan;
Aker, Karoline.
(2024)
Biochemical profiles and organ dysfunction in neonates with hypoxic-ischemic encephalopathy post-hoc analysis of the THIN trial.
BMC Pediatrics
Academic article
-
Aker, Karoline;
Støen, Ragnhild;
Thomas, Niranjan.
(2024)
Letter in response to the article: “Therapeutic hypothermia for neonatal encephalopathy in developing countries: Current evidence”.
Clinical Epidemiology and Global Health
Reader opinion piece
2023
-
Kristoffersen, Laila Marie;
Bergseng, Håkon;
Engesland, Helene;
Bagstevold, Anne;
Aker, Karoline;
Støen, Ragnhild.
(2023)
Skin-to-skin contact in the delivery room for very preterm infants: a randomised clinical trial.
BMJ Paediatrics Open
Academic article
2022
-
Aker, Karoline;
Støen, Ragnhild;
Håberg, Asta;
Thomas, Niranjan.
(2022)
Perinatal asphyxia in a global perspective: How can we improve outcomes?.
Norges teknisk-naturvitenskapelige universitet
Norges teknisk-naturvitenskapelige universitet
Doctoral dissertation
2021
-
Aker, Karoline;
Thomas, Niranjan;
Adde, Lars;
Koshy, Beena;
Martinez-Biarge, Miriam;
Nakken, Ingeborg Elise.
(2021)
Prediction of outcome from MRI and general movements assessment after hypoxic-ischaemic encephalopathy in low-income and middle-income countries: data from a randomised controlled trial.
Archives of Disease in Childhood: Fetal and Neonatal Edition
Academic article
-
Aker, Karoline;
Støen, Ragnhild;
Martinez-Biarge, Miriam;
Thomas, Niranjan.
(2021)
Questions about the HELIX trial.
The Lancet Global Health
Reader opinion piece
-
Thomas, Niranjan;
Støen, Ragnhild;
Aker, Karoline;
Martinez-Biarge, Miriam;
Nakken, Ingeborg Elise;
Håberg, Asta.
(2021)
Rise and Fall of Therapeutic Hypothermia in Low‑Resource Settings: Lessons from the HELIX Trial: Correspondence.
Indian Journal of Pediatrics (IJP)
Reader opinion piece
2019
-
Aker, Karoline;
Støen, Ragnhild;
Eikenes, Live;
Martinez-Biarge, Miriam;
Nakken, Ingeborg Elise;
Håberg, Asta.
(2019)
Therapeutic hypothermia for neonatal hypoxic-ischaemic encephalopathy in India (THIN study): a randomised controlled trial.
Archives of Disease in Childhood: Fetal and Neonatal Edition
Academic article
2015
-
Aker, Karoline;
Brantberg, Anne;
Nyrnes, Siri Ann.
(2015)
Prenatal constriction of the ductus arteriosus following maternal diclofenac medication in the third trimester.
BMJ Case Reports
Academic article
Journal publications
-
Kristoffersen, Laila Marie;
Støen, Ragnhild;
Bergseng, Håkon;
Flottorp, Silje Tjøm;
Magerøy, Grete;
Grunewaldt, Kristine Hermansen.
(2025)
Immediate Skin-to-Skin Contact in Very Preterm Neonates and Early Childhood Neurodevelopment: A Randomized Clinical Trial.
JAMA Network Open
Academic article
-
Francke, Karen Haugvik;
Støen, Ragnhild;
Thomas, Niranjan;
Aker, Karoline.
(2024)
Biochemical profiles and organ dysfunction in neonates with hypoxic-ischemic encephalopathy post-hoc analysis of the THIN trial.
BMC Pediatrics
Academic article
-
Aker, Karoline;
Støen, Ragnhild;
Thomas, Niranjan.
(2024)
Letter in response to the article: “Therapeutic hypothermia for neonatal encephalopathy in developing countries: Current evidence”.
Clinical Epidemiology and Global Health
Reader opinion piece
-
Kristoffersen, Laila Marie;
Bergseng, Håkon;
Engesland, Helene;
Bagstevold, Anne;
Aker, Karoline;
Støen, Ragnhild.
(2023)
Skin-to-skin contact in the delivery room for very preterm infants: a randomised clinical trial.
BMJ Paediatrics Open
Academic article
-
Aker, Karoline;
Thomas, Niranjan;
Adde, Lars;
Koshy, Beena;
Martinez-Biarge, Miriam;
Nakken, Ingeborg Elise.
(2021)
Prediction of outcome from MRI and general movements assessment after hypoxic-ischaemic encephalopathy in low-income and middle-income countries: data from a randomised controlled trial.
Archives of Disease in Childhood: Fetal and Neonatal Edition
Academic article
-
Aker, Karoline;
Støen, Ragnhild;
Martinez-Biarge, Miriam;
Thomas, Niranjan.
(2021)
Questions about the HELIX trial.
The Lancet Global Health
Reader opinion piece
-
Thomas, Niranjan;
Støen, Ragnhild;
Aker, Karoline;
Martinez-Biarge, Miriam;
Nakken, Ingeborg Elise;
Håberg, Asta.
(2021)
Rise and Fall of Therapeutic Hypothermia in Low‑Resource Settings: Lessons from the HELIX Trial: Correspondence.
Indian Journal of Pediatrics (IJP)
Reader opinion piece
-
Aker, Karoline;
Støen, Ragnhild;
Eikenes, Live;
Martinez-Biarge, Miriam;
Nakken, Ingeborg Elise;
Håberg, Asta.
(2019)
Therapeutic hypothermia for neonatal hypoxic-ischaemic encephalopathy in India (THIN study): a randomised controlled trial.
Archives of Disease in Childhood: Fetal and Neonatal Edition
Academic article
-
Aker, Karoline;
Brantberg, Anne;
Nyrnes, Siri Ann.
(2015)
Prenatal constriction of the ductus arteriosus following maternal diclofenac medication in the third trimester.
BMJ Case Reports
Academic article
Report
-
Aker, Karoline;
Støen, Ragnhild;
Håberg, Asta;
Thomas, Niranjan.
(2022)
Perinatal asphyxia in a global perspective: How can we improve outcomes?.
Norges teknisk-naturvitenskapelige universitet
Norges teknisk-naturvitenskapelige universitet
Doctoral dissertation
Outreach
2021
-
PosterAker, Karoline; Støen, Ragnhild. (2021) Incidence of perinatal asphyxia and hypoxic-ischemic encephalopathy before and after implementation of therapeutic hypothermia – a population-based study. 4th Congress of joint European Neonatal Societies (jENS) 2021-09-14 - 2021-09-18
2018
-
PosterAker, Karoline; Støen, Ragnhild; Martinez-Biarge, Miriam; Fjørtoft, Toril Larsson; Adde, Lars; Thomas, Niranjan. (2018) General Movement Assessment and early MRI in a randomized trial of therapeutic hypothermia for infants with hypoxic-ischemic encephalopathy in India (THIN-study). Pediatric Academic Societies (PAS) Meeting , Toronto 2018-05-05 - 2018-05-08
-
PosterAker, Karoline; Støen, Ragnhild; Martinez-Biarge, Miriam; Thomas, Niranjan. (2018) A randomized controlled trial of therapeutic hypothermia for neonatal hypoxic-ischemic encephalopathy in India (THIN-study). Pediatric Academic Societies (PAS) Meeting , Toronto 2018-05-05 - 2018-05-08