Laurent Thomas
About
Researcher at the Unit for Molecular Biology, in the group for Bioinformatics and Gene Regulation, and in the K.G. Jebsen Center for Genetic Epidemiology.
Received a Ph.D. in bioinformatics and trained as a postdoctoral scientist at the Norwegian University of Science and Technology (NTNU), Trondheim. His research interests focus on gene regulation, particularly on single nucleotide polymorphisms, alternative polyadenylation and non-coding RNAs such as microRNAs and circular RNAs, but also genetic variants such as Single Nucleotide Polymorphisms (SNP), particulary SNP funcitonal changes, Genome-wide association studies (GWAS) and genotype quality control (QC).
Publications
2023
-
Solvin, Åshild Øksnevad;
Bjarkø, Vera Vik;
Thomas, Laurent Francois;
Berrospi, Patricia;
Hveem, Kristian;
Saunes, Marit;
Åsvold, Bjørn Olav;
Løset, Mari.
(2023)
Body Composition, Cardiometabolic Risk Factors and Comorbidities in Psoriasis and the Effect of HLA-C*06:02 Status: The HUNT Study, Norway.
Acta Dermato-Venereologica.
volum 103.
Academic article
-
Surakka, Ida;
Wolford, Brooke N.;
Ritchie, Scott C.;
Hornsby, Whitney E.;
Sutton, Nadia R.;
Gabrielsen, Maiken Elvestad;
Skogholt, Anne Heidi;
Thomas, Laurent Francois;
Inouye, Michael;
Hveem, Kristian;
Willer, Cristen J..
(2023)
Sex-Specific Survival Bias and Interaction Modeling in Coronary Artery Disease Risk Prediction.
Circulation: Genomic and precision medicine.
volum 16 (1).
Academic article
2022
-
Bahrami, Shahram;
Hindley, Guy Frederick Lanyon;
Winsvold, Bendik K S;
O'Connell, Kevin Sean;
Frei, Oleksandr;
Shadrin, Alexey;
Cheng, Weiqiu;
Bettella, Francesco;
Rødevand, Linn;
Ødegaard, Ketil Joachim;
Fan, Chun C;
Pirinen, Matti J;
Hautakangas, Heidi M;
Martinsen, Amy;
Skogholt, Anne Heidi;
Brumpton, Ben Michael;
Willer, Cristen J;
Tronvik, Erling Andreas;
Kristoffersen, Espen Saxhaug.
(2022)
Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools.
Brain.
volum 145 (1).
Academic article
-
Brumpton, Ben Michael;
Graham, Sarah;
Surakka, Ida;
Skogholt, Anne Heidi;
Løset, Mari;
Fritsche, Lars G.;
Wolford, Brooke;
Zhou, Wei;
Nielsen, Jonas Bille;
Holmen, Oddgeir Lingaas;
Gabrielsen, Maiken Elvestad;
Thomas, Laurent;
Bhatta, Laxmi;
Rasheed, Humaira;
Zhang, He;
Kang, Hyun Min;
Hornsby, Whitney;
Moksnes, Marta Riise;
Coward, Eivind.
(2022)
The HUNT study: A population-based cohort for genetic research.
Cell Genomics.
volum 2 (10).
Academic article
-
Gorski, Mathias;
Rasheed, Humaira;
Teumer, Alexander;
Thomas, Laurent;
Graham, Sarah E.;
Sveinbjornsson, Gardar;
Winkler, Thomas W.;
Günther, Felix;
Stark, Klaus J.;
Chai, Jin-Fang;
Tayo, Bamidele O.;
Wuttke, Matthias;
Li, Yong;
Tin, Adrienne;
Ahluwalia, Tarunveer S.;
Ärnlöv, Johan;
Åsvold, Bjørn Olav;
Bakker, Stephan J.L.;
Banas, Bernhard.
(2022)
Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies.
Kidney International.
volum 102 (3).
Academic article
-
Hartley, April;
Sanderson, Eleanor;
Granell, Raquel;
Paternoster, Lavinia;
Zheng, Jie;
Smith, George Davey;
Southam, Lorraine;
Hatzikotoulas, Konstantinos;
Boer, Cindy G.;
Van Meurs, Joyce;
Zeggini, Eleftheria;
Gregson, Celia L.;
Tobias, Jon H.;
Stefánsdóttir, Lilja;
Zhang, Yanfei;
De Almeida, Rodrigo Coutinho;
Wu, Tian T.;
Teder-Laving, Maris;
Skogholt, Anne Heidi.
(2022)
Using multivariable Mendelian randomization to estimate the causal effect of bone mineral density on osteoarthritis risk, independently of body mass index.
International Journal of Epidemiology.
volum 51 (4).
Academic article
-
Hautakangas, Heidi;
Winsvold, Bendik K S;
Ruotsalainen, Sanni;
Bjornsdottir, Gyda;
Harder, Aster V. E.;
Kogelman, Lisette J. A.;
Thomas, Laurent;
Noordam, Raymond;
Benner, Christian;
Gormley, Padhraig;
Artto, Ville;
Banasik, Karina;
Bjornsdottir, Anna;
Boomsma, Dorret I.;
Brumpton, Ben Michael;
Burgdorf, Kristoffer Sølvsten;
Buring, Julie E.;
Chalmer, Mona Ameri;
de Boer, Irene.
(2022)
Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles.
Nature Genetics.
volum 54.
Academic article
-
Løset, Mari;
Thomas, Laurent Francois;
Brumpton, Ben Michael;
Modalsli, Ellen Heilmann;
Gabrielsen, Maiken Elvestad;
Solvin, Åshild Øksnevad;
Saunes, Marit;
Willer, Cristen;
Åsvold, Bjørn Olav;
Hveem, Kristian;
Dand, Nick;
Tsoi, Lam C;
Nair, Rajan P.;
Smith, Catherine;
Barker, Jonathan N;
Simpson, Melanie Rae;
Elder, James E.;
The International Psoriasis, Gwas Consortium.
(2022)
Discovering novel genes and causal relationships for psoriasis: The HUNT study.
Acta Dermato-Venereologica.
Abstract
-
Mars, Nina;
Kerminen, Sini;
Feng, Yen-Chen A.;
Kanai, Masahiro;
Läll, Kristi;
Thomas, Laurent Francois;
Skogholt, Anne Heidi;
della Briotta Parolo, Pietro;
Neale, Benjamin M.;
Smoller, Jordan W.;
Gabrielsen, Maiken Elvestad;
Hveem, Kristian;
Mägi, Reedik;
Matsuda, Koichi;
Okada, Yukinori;
Pirinen, Matti;
Palotie, Aarno;
Ganna, Andrea;
Martin, Alicia R..
(2022)
Genome-wide risk prediction of common diseases across ancestries in one million people.
Cell Genomics.
volum 2 (4).
Academic article
-
Mishra, Aniket;
Malik, Rainer;
Hachiya, Tsuyoshi;
Jürgenson, Tuuli;
Namba, Shinichi;
Posner, Daniel C.;
Kamanu, Frederick K.;
Koido, Masaru;
Le Grand, Quentin;
Shi, Mingyang;
He, Yunye;
Georgakis, Marios K.;
Caro, Ilana;
Krebs, Kristine;
Liaw, Yi-Ching;
Vaura, Felix C.;
Kuang, Lin;
Winsvold, Bendik Kristoffer Slagsvold;
Srinivasasainagendra, Vinodh.
(2022)
Publisher Correction: Stroke genetics informs drug discovery and risk prediction across ancestries.
Nature.
Errata
-
Mishra, Aniket;
Malik, Rainer;
Hachiya, Tsuyoshi;
Jürgenson, Tuuli;
Namba, Shinichi;
Posner, Daniel C.;
Kamanu, Frederick K.;
Koido, Masaru;
Le Grand, Quentin;
Shi, Mingyang;
He, Yunye;
Georgakis, Marios K.;
Caro, Ilana;
Krebs, Kristine;
Liaw, Yi-Ching;
Vaura, Felix C.;
Lin, Kuang;
Winsvold, Bendik K S;
Srinivasasainagendra, Vinodh.
(2022)
Stroke genetics informs drug discovery and risk prediction across ancestries.
Nature.
volum 611 (7934).
Academic article
-
Mitchell, Brittany L.;
Saklatvala, Jake R.;
Dand, Nick;
Hagenbeek, Fiona A.;
Li, Xin;
Min, Josine L.;
Thomas, Laurent;
Bartels, Meike;
Jan Hottenga, Jouke;
Lupton, Michelle K.;
Boomsma, Dorret I.;
Dong, Xianjun;
Hveem, Kristian;
Løset, Mari;
Martin, Nicholas G.;
Barker, Jonathan N.;
Han, Jiali;
Smith, Catherine H.;
Rentería, Miguel E..
(2022)
Genome-wide association meta-analysis identifies 29 new acne susceptibility loci.
Nature Communications.
volum 13 (1).
Academic article
-
Solvin, Åshild Øksnevad;
Bjarkø, Vera Vik;
Thomas, Laurent Francois;
Berrospi, Patricia;
Hveem, Kristian;
Saunes, Marit;
Åsvold, Bjørn Olav;
Løset, Mari.
(2022)
Body composition, cardiometabolic risk factors and comorbidities in psoriasis and the effect of HLA-C*06:02 status in a general population.
Journal of Investigative Dermatology.
volum 138.
Abstract
-
Wightman, Douglas P.;
Jansen, Iris E.;
Savage, Jeanne E.;
Shadrin, Alexey;
Bahrami, Shahram;
Holland, Dominic;
Rongve, Arvid;
Børte, Sigrid;
Winsvold, Bendik K S;
Drange, Ole Kristian;
Martinsen, Amy;
Skogholt, Anne Heidi;
Willer, Cristen;
Bråthen, Geir;
Bosnes, Ingunn;
Nielsen, Jonas Bille;
Fritsche, Lars;
Thomas, Laurent;
Pedersen, Linda Margareth.
(2022)
Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer’s disease (Nature Genetics, (2021), 53, 9, (1276-1282), 10.1038/s41588-021-00921-z).
Nature Genetics.
volum 54 (7).
Errata
-
Winkler, Thomas W.;
Rasheed, Humaira;
Teumer, Alexander;
Gorski, Mathias;
Rowan, Bryce X.;
Stanzick, Kira J.;
Thomas, Laurent;
Tin, Adrienne;
Hoppmann, Anselm;
Chu, Audrey Y.;
Tayo, Bamidele;
Thio, Chris H. L.;
Cusi, Daniele;
Chai, Jin-Fang;
Sieber, Karsten B.;
Horn, Katrin;
Li, Man;
Scholz, Markus;
Cocca, Massimiliano.
(2022)
Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals.
Communications Biology.
volum 5 (580).
Academic article
2021
-
Boer, Cindy G.;
Hatzikotoulas, Konstantinos;
Southam, Lorraine;
Stefánsdóttir, Lilja;
Almeida, Rodrigo Coutinho de;
Zhang, Yanfei;
Wu, Tian T.;
Zheng, Jie;
Hartley, April;
Teder-Laving, Maris;
Skogholt, Anne Heidi;
Terao, Chikashi;
Zengini, Eleni;
Alexiadis, George;
Barysenka, Andrei;
Bjornsdottir, Gyda;
Gabrielsen, Maiken Elvestad;
Gilly, Arthur;
Ingvarsson, Thorvaldur.
(2021)
Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations.
Cell.
volum 184.
Academic article
-
Flatby, Helene Marie;
Rasheed, Humaira;
Ravi, Anuradha;
Thomas, Laurent;
Liyanarachi, Kristin Vardheim;
Afset, Jan Egil;
DeWan, Andrew;
Brumpton, Ben Michael;
Hveem, Kristian;
Åsvold, Bjørn Olav;
Simonsen, Gunnar Skov;
Furberg, Anne-Sofie;
Damås, Jan Kristian;
Solligård, Erik;
Rogne, Tormod.
(2021)
Risk of lower respiratory tract infections: a genome-wide association study with Mendelian randomization analysis in three independent European populations.
Clinical Microbiology and Infection (CMI).
volum 28 (5).
Academic article
-
Freidin, Maxim B.;
Tsepilov, Yakov A.;
Stanaway, Ian B.;
Meng, Weihua;
Hayward, Caroline;
Smith, Blair H.;
Khoury, Samar;
Parisien, Marc;
Bortsov, Andrey;
Diatchenko, Luda;
Børte, Sigrid;
Winsvold, Bendik K S;
Brumpton, Ben Michael;
Zwart, John-Anker;
Martinsen, Amy;
Skogholt, Anne Heidi;
Willer, Cristen;
Fors, Egil Andreas;
Heuch, Ingrid.
(2021)
Sex- and age-specific genetic analysis of chronic back pain.
Pain.
volum 162 (4).
Academic article
-
Harder, Aster V.E.;
Winsvold, Bendik K S;
Noordam, Raymond;
Vijfhuizen, Lisanne S.;
Børte, Sigrid;
Kogelman, Lisette J.A.;
de Boer, Irene;
Tronvik, Erling Andreas;
Rosendaal, Frits;
Willems van Dijk, Ko;
O'Connor, Emer;
Fourier, Carmen;
Thomas, Laurent;
Kristoffersen, Espen Saxhaug;
Fronczek, Rolf;
Pozo-Rosich, Patricia;
Jensen, Rigmor;
Ferrari, Michel D.;
Hansen, Thomas.
(2021)
Genetic Susceptibility Loci in Genomewide Association Study of Cluster Headache.
Annals of Neurology.
volum 90 (2).
Academic article
-
Johnsen, Marianne Bakke;
Magnusson, Karin;
Børte, Sigrid;
Gabrielsen, Maiken Elvestad;
Winsvold, Bendik K S;
Skogholt, Anne Heidi;
Thomas, Laurent;
Storheim, Kjersti;
Hveem, Kristian;
Zwart, John-Anker.
(2021)
Response to Letter to the Editor: ‘Comments on the paper presenting prediction models for incident hand OA in the HUNT study’.
Osteoarthritis and Cartilage.
volum 29 (2).
Letter to the editor
-
Khoury, Samar;
Parisien, Marc;
Thompson, Scott J.;
Vachon-Presseau, Etienne;
Roy, Mathieu;
Mitchell, Amy;
Winsvold, Bendik K S;
Skogholt, Anne Heidi;
Brumpton, Ben Michael;
Willer, Cristen J.;
Fors, Egil Andreas;
Heuch, Ingrid;
Nielsen, Jonas Bille;
Storheim, Kjersti;
Hagen, Knut;
Nilsen, Kristian Bernhard;
Hveem, Kristian;
Fritsche, Lars;
Thomas, Laurent.
(2021)
Genome-wide analysis identifies impaired axonogenesis in chronic overlapping pain conditions.
Brain.
volum 145 (3).
Academic article
-
Moksnes, Marta Riise;
Røsjø, Helge;
Richmond, Anne;
Lyngbakken, Magnus N;
Graham, Sarah E;
Hansen, Ailin Falkmo;
Wolford, Brooke N;
Gagliano Taliun, Sarah A;
Lefaive, Jonathon;
Rasheed, Humaira;
Thomas, Laurent;
Zhou, Wei;
Aung, Nay;
Surakka, Ida;
Douville, Nicholas J;
Campbell, Archie;
Porteous, David J;
Petersen, Steffen E;
Munroe, Patricia B.
(2021)
Genome-wide association study of cardiac troponin i in the general population.
Human Molecular Genetics.
volum 30 (21).
Academic article
-
Rahman, Shafiqur;
Winsvold, Bendik K S;
Chavez, Sergio;
Børte, Sigrid;
Tsepilov, Vakov;
Sharapov, Sodbo Zh;
Martinsen, Amy;
Skogholt, Anne Heidi;
Brumpton, Ben Michael;
Willer, Cristen;
Heuch, Ingrid;
Mundal, Ingunn Pernille;
Nielsen, Jonas Bille;
Storheim, Kjersti;
Nilsen, Kristian Bernhard;
Fritsche, Lars;
Thomas, Laurent;
Pedersen, Linda Margareth;
Gabrielsen, Maiken Elvestad.
(2021)
Genome-wide association study identifies RNF123 locus as associated with chronic widespread musculoskeletal pain.
Annals of the Rheumatic Diseases.
volum 80 (9).
Academic article
-
Rasheed, Humaira;
Zheng, Jie;
Rees, Jessica;
Sanderson, Eleanor;
Thomas, Laurent;
Richardson, Tom G.;
Fang, Si;
Bekkevold, Ole-Jørgen;
Stovner, Endre Bakken;
Gabrielsen, Maiken Elvestad;
Skogholt, Anne Heidi;
Romundstad, Solfrid;
Brumpton, Ben Michael;
Hallan, Stein;
Willer, Cristen;
Burgess, Stephen;
Hveem, Kristian;
Smith, George Davey;
Gaunt, Tom R..
(2021)
The causal effects of serum lipids and apolipoproteins on kidney function: Multivariable and bidirectional Mendelian-randomization analyses.
International Journal of Epidemiology.
volum 50 (5).
Academic article
-
Rogne, Tormod;
Liyanarachi, Kristin Vardheim;
Rasheed, Humaira;
Thomas, Laurent;
Flatby, Helene Marie;
Stenvik, Jørgen;
Løset, Mari;
Gill, Dipender;
Burgess, Stephen;
Willer, Cristen J;
Hveem, Kristian;
Åsvold, Bjørn Olav;
Brumpton, Ben Michael;
DeWan, Andrew;
Solligård, Erik;
Damås, Jan Kristian.
(2021)
GWAS Identifies LINC01184/SLC12A2 as a Risk Locus for Skin and Soft Tissue Infections.
Journal of Investigative Dermatology.
volum 141 (8).
Academic article
-
Stanzick, Kira J.;
Li, Yong;
Schlosser, Pascal;
Gorski, Mathias;
Wuttke, Matthias;
Thomas, Laurent;
Rasheed, Humaira;
Rowan, Bryce X.;
Graham, Sarah E.;
Vanderweff, Brett R.;
Patil, Snehal B.;
Robinson-Cohen, Cassiane;
Gaziano, John M.;
O’Donnell, Christopher J.;
Willer, Cristen J.;
Hallan, Stein;
Åsvold, Bjørn Olav;
Gessner, Andre;
Hung, Adriana M..
(2021)
Discovery and prioritization of variants and genes for kidney function in >1.2 million individuals.
Nature Communications.
volum 12 (1).
Academic article
-
Wightman, Douglas P.;
Jansen, Iris E.;
Savage, Jeanne E.;
Shadrin, Alexey;
Bahrami, Shahram;
Holland, Dominic;
Rongve, Arvid;
Børte, Sigrid;
Winsvold, Bendik K S;
Drange, Ole Kristian;
Mitchell, Amy;
Skogholt, Anne Heidi;
Willer, Cristen;
Bråthen, Geir;
Bosnes, Ingunn;
Nielsen, Jonas Bille;
Fritsche, Lars;
Thomas, Laurent;
Pedersen, Linda Margareth.
(2021)
A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease.
Nature Genetics.
volum 53.
Academic article
-
Winsvold, Bendik K S;
Kitsos, Ioannis;
Thomas, Laurent;
Skogholt, Anne Heidi;
Gabrielsen, Maiken Elvestad;
Zwart, John Anker Henrik;
Nilsen, Kristian Bernhard.
(2021)
Genome-Wide Association Study of 2,093 Cases With Idiopathic Polyneuropathy and 445,256 Controls Identifies First Susceptibility Loci.
Frontiers in Neurology.
volum 12.
Academic article
-
Zheng, Jie;
Zhang, Yuemiao;
Rasheed, Humaira;
Walker, Venexia M.;
Sugawara, Yuka;
Li, Jiachen;
Leng, Yue;
Elsworth, Benjamin;
Wootton, Robyn E.;
Fang, Si;
Yang, Qian;
Burgess, Stephen;
Haycock, Philip C.;
Borges, Maria Carolina;
Carnegie, Rebecca;
Cho, Yoonsu;
Howell, Amy;
Robinson, Jamie;
Thomas, Laurent.
(2021)
Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease.
International Journal of Epidemiology.
volum 50 (6).
Academic article
-
Zheng, Thenghao;
Ellinghaus, David;
Juzenas, Simonas;
Cossais, François;
Burmeister, Greta;
Mayr, Gabriele;
Jørgensen, Isabella Friis;
Teder-Laving, Maris;
Skogholt, Anne Heidi;
Chen, Sisi;
Strege, Peter R;
Ito, Go;
Banasik, Karina;
Becker, Thomas;
Bokelmann, Frank;
Brunak, Søren;
Buch, Stephan;
Clausnitzer, Hartmut;
Datz, Christian.
(2021)
Genome-wide analysis of 944 133 individuals provides insights into the etiology of haemorrhoidal disease.
Gut.
volum 70 (8).
Academic article
2020
-
Børte, Sigrid;
Zwart, John-Anker;
Skogholt, Anne Heidi;
Gabrielsen, Maiken Elvestad;
Thomas, Laurent;
Fritsche, Lars;
Surakke, Ida;
Nielsen, Jonas B.;
Zhou, Wei;
Wolford, Brooke;
Vigeland, Magnus Dehli;
Hagen, Knut;
Kristoffersen, Espen Saxhaug;
Nyholt, Dale R;
Chasman, Daniel I;
Brumpton, Ben Michael;
Willer, Christen;
Winsvold, Bendik K S.
(2020)
Mitochondrial genome-wide association study of migraine – the HUNT Study.
Cephalalgia.
volum 40 (6).
Academic article
-
Johnsen, Marianne Bakke;
Magnusson, Karin;
Børte, Sigrid;
Gabrielsen, Maiken Elvestad;
Winsvold, Bendik K S;
Skogholt, Anne Heidi;
Thomas, Laurent;
Storheim, Kjersti;
Hveem, Kristian;
Zwart, John-Anker.
(2020)
Development and validation of a prediction model for incident hand osteoarthritis in the HUNT study.
Osteoarthritis and Cartilage.
volum 28 (7).
Academic article
-
Klarin, Derek;
Verma, Shefali Setia;
Judy, Renae;
Dikilitas, Ozan;
Wolford, Brooke N.;
Paranjpe, Ishan;
Levin, Michael G.;
Pan, Cuiping;
Tcheandjieu, Catherine;
Spin, Joshua M.;
Lynch, Julie;
Assimes, Themistocles L;
Nyrønning, Linn Ålstedt;
Mattsson, Erney;
Edwards, Todd L.;
Denny, Josh C.;
Larson, Eric B.;
Lee, Ming Ta Michael;
Carrell, David S..
(2020)
Genetic Architecture of Abdominal Aortic Aneurysm in the Million Veteran Program.
Circulation.
volum 142 (17).
Academic article
2019
-
Løset, Mari;
Thomas, Laurent;
Brumpton, Ben Michael;
Wolford, Brooke N.;
Holmen, Oddgeir;
Luetge, Almut;
Skogholt, Anne Heidi;
Modalsli, Ellen Heilmann;
Solvin, Åshild Øksnevad;
Fritsche, Lars;
Nielsen, Jonas Bille;
Zhou, Wei;
Gabrielsen, Maiken Elvestad;
Saunes, Marit;
Willer, Cristen;
Hveem, Kristian.
(2019)
Genome-wide association study of psoriasis suggests a new risk locus on chromosome 10: The HUNT Study.
Forum for Nordic Dermato-Venereology.
volum 24 (2).
Abstract
2016
-
Stracquadanio, Giovanni;
Wang, Xuting;
Wallace, Marsha D;
Grawenda, Anna M.;
Zhang, Ping;
Hewitt, Juliet;
Zeron-Medina, Jorge;
Castro-Giner, Francesc;
Tomlinson, Ian P;
Goding, Colin R.;
Cygan, Kamil J;
Fairbrother, William G;
Thomas, Laurent;
Sætrom, Pål;
Gemignani, Federica;
Landi, Stefano;
Schuster-Böckler, Benjamin;
Bell, Douglas A;
Bond, Gareth L..
(2016)
The importance of p53 pathway genetics in inherited and somatic cancer genomes.
Nature Reviews Cancer.
volum 16 (4).
Academic article
2014
-
Razick, Sabry;
Mocnik, Rok;
Thomas, Laurent;
Ryeng, Einar;
Drabløs, Finn;
Sætrom, Pål.
(2014)
The eGenVar data management system--cataloguing and sharing sensitive data and metadata for the life sciences.
Database: The Journal of Biological Databases and Curation.
Academic article
-
Thomas, Laurent;
Sætrom, Pål.
(2014)
Circular RNAs are depleted of polymorphisms at microRNA binding sites.
Bioinformatics.
volum 30 (16).
Academic article
2012
-
Thomas, Laurent.
(2012)
Effects of single-nucleotide polymorphisms on microRNA-based gene regulation and their association with disease.
2012. ISBN 978-82-471-3932-5. Doktoravhandlinger ved NTNU (2012:307).
Doctoral dissertation
-
Thomas, Laurent;
Sætrom, Pål.
(2012)
Single Nucleotide Polymorphisms Can Create Alternative Polyadenylation Signals and Affect Gene Expression through Loss of MicroRNA-Regulation.
PLoS Computational Biology.
volum 8 (8).
Academic article
2011
-
Thomas, Laurent;
Saito, Takaya;
Sætrom, Pål.
(2011)
Inferring causative variants in microRNA target sites.
Nucleic Acids Research (NAR).
volum 39 (16).
Academic article
2009
-
Sætrom, Pål;
Biesinger, Jacob;
Li, Sierra M.;
Smith, David;
Thomas, Laurent Francois;
Majzoub, Karim;
Rivas, Guillermo E.;
Alluin, Jessica;
Rossi, John J.;
Krontiris, Theodore G.;
Weitzel, Jeffrey;
Daly, Mary B.;
Benson, Al B.;
Kirkwood, John M.;
O'Dwyer, Peter J.;
Sutphen, Rebecca;
Stewart, James A.;
Johnson, David;
Larson, Garrett P..
(2009)
A Risk Variant in an miR-125b Binding Site in BMPR1B Is Associated with Breast Cancer Pathogenesis.
Cancer Research.
volum 69 (18).
Academic article
Journal publications
-
Solvin, Åshild Øksnevad;
Bjarkø, Vera Vik;
Thomas, Laurent Francois;
Berrospi, Patricia;
Hveem, Kristian;
Saunes, Marit;
Åsvold, Bjørn Olav;
Løset, Mari.
(2023)
Body Composition, Cardiometabolic Risk Factors and Comorbidities in Psoriasis and the Effect of HLA-C*06:02 Status: The HUNT Study, Norway.
Acta Dermato-Venereologica.
volum 103.
Academic article
-
Surakka, Ida;
Wolford, Brooke N.;
Ritchie, Scott C.;
Hornsby, Whitney E.;
Sutton, Nadia R.;
Gabrielsen, Maiken Elvestad;
Skogholt, Anne Heidi;
Thomas, Laurent Francois;
Inouye, Michael;
Hveem, Kristian;
Willer, Cristen J..
(2023)
Sex-Specific Survival Bias and Interaction Modeling in Coronary Artery Disease Risk Prediction.
Circulation: Genomic and precision medicine.
volum 16 (1).
Academic article
-
Bahrami, Shahram;
Hindley, Guy Frederick Lanyon;
Winsvold, Bendik K S;
O'Connell, Kevin Sean;
Frei, Oleksandr;
Shadrin, Alexey;
Cheng, Weiqiu;
Bettella, Francesco;
Rødevand, Linn;
Ødegaard, Ketil Joachim;
Fan, Chun C;
Pirinen, Matti J;
Hautakangas, Heidi M;
Martinsen, Amy;
Skogholt, Anne Heidi;
Brumpton, Ben Michael;
Willer, Cristen J;
Tronvik, Erling Andreas;
Kristoffersen, Espen Saxhaug.
(2022)
Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools.
Brain.
volum 145 (1).
Academic article
-
Brumpton, Ben Michael;
Graham, Sarah;
Surakka, Ida;
Skogholt, Anne Heidi;
Løset, Mari;
Fritsche, Lars G.;
Wolford, Brooke;
Zhou, Wei;
Nielsen, Jonas Bille;
Holmen, Oddgeir Lingaas;
Gabrielsen, Maiken Elvestad;
Thomas, Laurent;
Bhatta, Laxmi;
Rasheed, Humaira;
Zhang, He;
Kang, Hyun Min;
Hornsby, Whitney;
Moksnes, Marta Riise;
Coward, Eivind.
(2022)
The HUNT study: A population-based cohort for genetic research.
Cell Genomics.
volum 2 (10).
Academic article
-
Gorski, Mathias;
Rasheed, Humaira;
Teumer, Alexander;
Thomas, Laurent;
Graham, Sarah E.;
Sveinbjornsson, Gardar;
Winkler, Thomas W.;
Günther, Felix;
Stark, Klaus J.;
Chai, Jin-Fang;
Tayo, Bamidele O.;
Wuttke, Matthias;
Li, Yong;
Tin, Adrienne;
Ahluwalia, Tarunveer S.;
Ärnlöv, Johan;
Åsvold, Bjørn Olav;
Bakker, Stephan J.L.;
Banas, Bernhard.
(2022)
Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies.
Kidney International.
volum 102 (3).
Academic article
-
Hartley, April;
Sanderson, Eleanor;
Granell, Raquel;
Paternoster, Lavinia;
Zheng, Jie;
Smith, George Davey;
Southam, Lorraine;
Hatzikotoulas, Konstantinos;
Boer, Cindy G.;
Van Meurs, Joyce;
Zeggini, Eleftheria;
Gregson, Celia L.;
Tobias, Jon H.;
Stefánsdóttir, Lilja;
Zhang, Yanfei;
De Almeida, Rodrigo Coutinho;
Wu, Tian T.;
Teder-Laving, Maris;
Skogholt, Anne Heidi.
(2022)
Using multivariable Mendelian randomization to estimate the causal effect of bone mineral density on osteoarthritis risk, independently of body mass index.
International Journal of Epidemiology.
volum 51 (4).
Academic article
-
Hautakangas, Heidi;
Winsvold, Bendik K S;
Ruotsalainen, Sanni;
Bjornsdottir, Gyda;
Harder, Aster V. E.;
Kogelman, Lisette J. A.;
Thomas, Laurent;
Noordam, Raymond;
Benner, Christian;
Gormley, Padhraig;
Artto, Ville;
Banasik, Karina;
Bjornsdottir, Anna;
Boomsma, Dorret I.;
Brumpton, Ben Michael;
Burgdorf, Kristoffer Sølvsten;
Buring, Julie E.;
Chalmer, Mona Ameri;
de Boer, Irene.
(2022)
Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles.
Nature Genetics.
volum 54.
Academic article
-
Løset, Mari;
Thomas, Laurent Francois;
Brumpton, Ben Michael;
Modalsli, Ellen Heilmann;
Gabrielsen, Maiken Elvestad;
Solvin, Åshild Øksnevad;
Saunes, Marit;
Willer, Cristen;
Åsvold, Bjørn Olav;
Hveem, Kristian;
Dand, Nick;
Tsoi, Lam C;
Nair, Rajan P.;
Smith, Catherine;
Barker, Jonathan N;
Simpson, Melanie Rae;
Elder, James E.;
The International Psoriasis, Gwas Consortium.
(2022)
Discovering novel genes and causal relationships for psoriasis: The HUNT study.
Acta Dermato-Venereologica.
Abstract
-
Mars, Nina;
Kerminen, Sini;
Feng, Yen-Chen A.;
Kanai, Masahiro;
Läll, Kristi;
Thomas, Laurent Francois;
Skogholt, Anne Heidi;
della Briotta Parolo, Pietro;
Neale, Benjamin M.;
Smoller, Jordan W.;
Gabrielsen, Maiken Elvestad;
Hveem, Kristian;
Mägi, Reedik;
Matsuda, Koichi;
Okada, Yukinori;
Pirinen, Matti;
Palotie, Aarno;
Ganna, Andrea;
Martin, Alicia R..
(2022)
Genome-wide risk prediction of common diseases across ancestries in one million people.
Cell Genomics.
volum 2 (4).
Academic article
-
Mishra, Aniket;
Malik, Rainer;
Hachiya, Tsuyoshi;
Jürgenson, Tuuli;
Namba, Shinichi;
Posner, Daniel C.;
Kamanu, Frederick K.;
Koido, Masaru;
Le Grand, Quentin;
Shi, Mingyang;
He, Yunye;
Georgakis, Marios K.;
Caro, Ilana;
Krebs, Kristine;
Liaw, Yi-Ching;
Vaura, Felix C.;
Kuang, Lin;
Winsvold, Bendik Kristoffer Slagsvold;
Srinivasasainagendra, Vinodh.
(2022)
Publisher Correction: Stroke genetics informs drug discovery and risk prediction across ancestries.
Nature.
Errata
-
Mishra, Aniket;
Malik, Rainer;
Hachiya, Tsuyoshi;
Jürgenson, Tuuli;
Namba, Shinichi;
Posner, Daniel C.;
Kamanu, Frederick K.;
Koido, Masaru;
Le Grand, Quentin;
Shi, Mingyang;
He, Yunye;
Georgakis, Marios K.;
Caro, Ilana;
Krebs, Kristine;
Liaw, Yi-Ching;
Vaura, Felix C.;
Lin, Kuang;
Winsvold, Bendik K S;
Srinivasasainagendra, Vinodh.
(2022)
Stroke genetics informs drug discovery and risk prediction across ancestries.
Nature.
volum 611 (7934).
Academic article
-
Mitchell, Brittany L.;
Saklatvala, Jake R.;
Dand, Nick;
Hagenbeek, Fiona A.;
Li, Xin;
Min, Josine L.;
Thomas, Laurent;
Bartels, Meike;
Jan Hottenga, Jouke;
Lupton, Michelle K.;
Boomsma, Dorret I.;
Dong, Xianjun;
Hveem, Kristian;
Løset, Mari;
Martin, Nicholas G.;
Barker, Jonathan N.;
Han, Jiali;
Smith, Catherine H.;
Rentería, Miguel E..
(2022)
Genome-wide association meta-analysis identifies 29 new acne susceptibility loci.
Nature Communications.
volum 13 (1).
Academic article
-
Solvin, Åshild Øksnevad;
Bjarkø, Vera Vik;
Thomas, Laurent Francois;
Berrospi, Patricia;
Hveem, Kristian;
Saunes, Marit;
Åsvold, Bjørn Olav;
Løset, Mari.
(2022)
Body composition, cardiometabolic risk factors and comorbidities in psoriasis and the effect of HLA-C*06:02 status in a general population.
Journal of Investigative Dermatology.
volum 138.
Abstract
-
Wightman, Douglas P.;
Jansen, Iris E.;
Savage, Jeanne E.;
Shadrin, Alexey;
Bahrami, Shahram;
Holland, Dominic;
Rongve, Arvid;
Børte, Sigrid;
Winsvold, Bendik K S;
Drange, Ole Kristian;
Martinsen, Amy;
Skogholt, Anne Heidi;
Willer, Cristen;
Bråthen, Geir;
Bosnes, Ingunn;
Nielsen, Jonas Bille;
Fritsche, Lars;
Thomas, Laurent;
Pedersen, Linda Margareth.
(2022)
Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer’s disease (Nature Genetics, (2021), 53, 9, (1276-1282), 10.1038/s41588-021-00921-z).
Nature Genetics.
volum 54 (7).
Errata
-
Winkler, Thomas W.;
Rasheed, Humaira;
Teumer, Alexander;
Gorski, Mathias;
Rowan, Bryce X.;
Stanzick, Kira J.;
Thomas, Laurent;
Tin, Adrienne;
Hoppmann, Anselm;
Chu, Audrey Y.;
Tayo, Bamidele;
Thio, Chris H. L.;
Cusi, Daniele;
Chai, Jin-Fang;
Sieber, Karsten B.;
Horn, Katrin;
Li, Man;
Scholz, Markus;
Cocca, Massimiliano.
(2022)
Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals.
Communications Biology.
volum 5 (580).
Academic article
-
Boer, Cindy G.;
Hatzikotoulas, Konstantinos;
Southam, Lorraine;
Stefánsdóttir, Lilja;
Almeida, Rodrigo Coutinho de;
Zhang, Yanfei;
Wu, Tian T.;
Zheng, Jie;
Hartley, April;
Teder-Laving, Maris;
Skogholt, Anne Heidi;
Terao, Chikashi;
Zengini, Eleni;
Alexiadis, George;
Barysenka, Andrei;
Bjornsdottir, Gyda;
Gabrielsen, Maiken Elvestad;
Gilly, Arthur;
Ingvarsson, Thorvaldur.
(2021)
Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations.
Cell.
volum 184.
Academic article
-
Flatby, Helene Marie;
Rasheed, Humaira;
Ravi, Anuradha;
Thomas, Laurent;
Liyanarachi, Kristin Vardheim;
Afset, Jan Egil;
DeWan, Andrew;
Brumpton, Ben Michael;
Hveem, Kristian;
Åsvold, Bjørn Olav;
Simonsen, Gunnar Skov;
Furberg, Anne-Sofie;
Damås, Jan Kristian;
Solligård, Erik;
Rogne, Tormod.
(2021)
Risk of lower respiratory tract infections: a genome-wide association study with Mendelian randomization analysis in three independent European populations.
Clinical Microbiology and Infection (CMI).
volum 28 (5).
Academic article
-
Freidin, Maxim B.;
Tsepilov, Yakov A.;
Stanaway, Ian B.;
Meng, Weihua;
Hayward, Caroline;
Smith, Blair H.;
Khoury, Samar;
Parisien, Marc;
Bortsov, Andrey;
Diatchenko, Luda;
Børte, Sigrid;
Winsvold, Bendik K S;
Brumpton, Ben Michael;
Zwart, John-Anker;
Martinsen, Amy;
Skogholt, Anne Heidi;
Willer, Cristen;
Fors, Egil Andreas;
Heuch, Ingrid.
(2021)
Sex- and age-specific genetic analysis of chronic back pain.
Pain.
volum 162 (4).
Academic article
-
Harder, Aster V.E.;
Winsvold, Bendik K S;
Noordam, Raymond;
Vijfhuizen, Lisanne S.;
Børte, Sigrid;
Kogelman, Lisette J.A.;
de Boer, Irene;
Tronvik, Erling Andreas;
Rosendaal, Frits;
Willems van Dijk, Ko;
O'Connor, Emer;
Fourier, Carmen;
Thomas, Laurent;
Kristoffersen, Espen Saxhaug;
Fronczek, Rolf;
Pozo-Rosich, Patricia;
Jensen, Rigmor;
Ferrari, Michel D.;
Hansen, Thomas.
(2021)
Genetic Susceptibility Loci in Genomewide Association Study of Cluster Headache.
Annals of Neurology.
volum 90 (2).
Academic article
-
Johnsen, Marianne Bakke;
Magnusson, Karin;
Børte, Sigrid;
Gabrielsen, Maiken Elvestad;
Winsvold, Bendik K S;
Skogholt, Anne Heidi;
Thomas, Laurent;
Storheim, Kjersti;
Hveem, Kristian;
Zwart, John-Anker.
(2021)
Response to Letter to the Editor: ‘Comments on the paper presenting prediction models for incident hand OA in the HUNT study’.
Osteoarthritis and Cartilage.
volum 29 (2).
Letter to the editor
-
Khoury, Samar;
Parisien, Marc;
Thompson, Scott J.;
Vachon-Presseau, Etienne;
Roy, Mathieu;
Mitchell, Amy;
Winsvold, Bendik K S;
Skogholt, Anne Heidi;
Brumpton, Ben Michael;
Willer, Cristen J.;
Fors, Egil Andreas;
Heuch, Ingrid;
Nielsen, Jonas Bille;
Storheim, Kjersti;
Hagen, Knut;
Nilsen, Kristian Bernhard;
Hveem, Kristian;
Fritsche, Lars;
Thomas, Laurent.
(2021)
Genome-wide analysis identifies impaired axonogenesis in chronic overlapping pain conditions.
Brain.
volum 145 (3).
Academic article
-
Moksnes, Marta Riise;
Røsjø, Helge;
Richmond, Anne;
Lyngbakken, Magnus N;
Graham, Sarah E;
Hansen, Ailin Falkmo;
Wolford, Brooke N;
Gagliano Taliun, Sarah A;
Lefaive, Jonathon;
Rasheed, Humaira;
Thomas, Laurent;
Zhou, Wei;
Aung, Nay;
Surakka, Ida;
Douville, Nicholas J;
Campbell, Archie;
Porteous, David J;
Petersen, Steffen E;
Munroe, Patricia B.
(2021)
Genome-wide association study of cardiac troponin i in the general population.
Human Molecular Genetics.
volum 30 (21).
Academic article
-
Rahman, Shafiqur;
Winsvold, Bendik K S;
Chavez, Sergio;
Børte, Sigrid;
Tsepilov, Vakov;
Sharapov, Sodbo Zh;
Martinsen, Amy;
Skogholt, Anne Heidi;
Brumpton, Ben Michael;
Willer, Cristen;
Heuch, Ingrid;
Mundal, Ingunn Pernille;
Nielsen, Jonas Bille;
Storheim, Kjersti;
Nilsen, Kristian Bernhard;
Fritsche, Lars;
Thomas, Laurent;
Pedersen, Linda Margareth;
Gabrielsen, Maiken Elvestad.
(2021)
Genome-wide association study identifies RNF123 locus as associated with chronic widespread musculoskeletal pain.
Annals of the Rheumatic Diseases.
volum 80 (9).
Academic article
-
Rasheed, Humaira;
Zheng, Jie;
Rees, Jessica;
Sanderson, Eleanor;
Thomas, Laurent;
Richardson, Tom G.;
Fang, Si;
Bekkevold, Ole-Jørgen;
Stovner, Endre Bakken;
Gabrielsen, Maiken Elvestad;
Skogholt, Anne Heidi;
Romundstad, Solfrid;
Brumpton, Ben Michael;
Hallan, Stein;
Willer, Cristen;
Burgess, Stephen;
Hveem, Kristian;
Smith, George Davey;
Gaunt, Tom R..
(2021)
The causal effects of serum lipids and apolipoproteins on kidney function: Multivariable and bidirectional Mendelian-randomization analyses.
International Journal of Epidemiology.
volum 50 (5).
Academic article
-
Rogne, Tormod;
Liyanarachi, Kristin Vardheim;
Rasheed, Humaira;
Thomas, Laurent;
Flatby, Helene Marie;
Stenvik, Jørgen;
Løset, Mari;
Gill, Dipender;
Burgess, Stephen;
Willer, Cristen J;
Hveem, Kristian;
Åsvold, Bjørn Olav;
Brumpton, Ben Michael;
DeWan, Andrew;
Solligård, Erik;
Damås, Jan Kristian.
(2021)
GWAS Identifies LINC01184/SLC12A2 as a Risk Locus for Skin and Soft Tissue Infections.
Journal of Investigative Dermatology.
volum 141 (8).
Academic article
-
Stanzick, Kira J.;
Li, Yong;
Schlosser, Pascal;
Gorski, Mathias;
Wuttke, Matthias;
Thomas, Laurent;
Rasheed, Humaira;
Rowan, Bryce X.;
Graham, Sarah E.;
Vanderweff, Brett R.;
Patil, Snehal B.;
Robinson-Cohen, Cassiane;
Gaziano, John M.;
O’Donnell, Christopher J.;
Willer, Cristen J.;
Hallan, Stein;
Åsvold, Bjørn Olav;
Gessner, Andre;
Hung, Adriana M..
(2021)
Discovery and prioritization of variants and genes for kidney function in >1.2 million individuals.
Nature Communications.
volum 12 (1).
Academic article
-
Wightman, Douglas P.;
Jansen, Iris E.;
Savage, Jeanne E.;
Shadrin, Alexey;
Bahrami, Shahram;
Holland, Dominic;
Rongve, Arvid;
Børte, Sigrid;
Winsvold, Bendik K S;
Drange, Ole Kristian;
Mitchell, Amy;
Skogholt, Anne Heidi;
Willer, Cristen;
Bråthen, Geir;
Bosnes, Ingunn;
Nielsen, Jonas Bille;
Fritsche, Lars;
Thomas, Laurent;
Pedersen, Linda Margareth.
(2021)
A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease.
Nature Genetics.
volum 53.
Academic article
-
Winsvold, Bendik K S;
Kitsos, Ioannis;
Thomas, Laurent;
Skogholt, Anne Heidi;
Gabrielsen, Maiken Elvestad;
Zwart, John Anker Henrik;
Nilsen, Kristian Bernhard.
(2021)
Genome-Wide Association Study of 2,093 Cases With Idiopathic Polyneuropathy and 445,256 Controls Identifies First Susceptibility Loci.
Frontiers in Neurology.
volum 12.
Academic article
-
Zheng, Jie;
Zhang, Yuemiao;
Rasheed, Humaira;
Walker, Venexia M.;
Sugawara, Yuka;
Li, Jiachen;
Leng, Yue;
Elsworth, Benjamin;
Wootton, Robyn E.;
Fang, Si;
Yang, Qian;
Burgess, Stephen;
Haycock, Philip C.;
Borges, Maria Carolina;
Carnegie, Rebecca;
Cho, Yoonsu;
Howell, Amy;
Robinson, Jamie;
Thomas, Laurent.
(2021)
Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease.
International Journal of Epidemiology.
volum 50 (6).
Academic article
-
Zheng, Thenghao;
Ellinghaus, David;
Juzenas, Simonas;
Cossais, François;
Burmeister, Greta;
Mayr, Gabriele;
Jørgensen, Isabella Friis;
Teder-Laving, Maris;
Skogholt, Anne Heidi;
Chen, Sisi;
Strege, Peter R;
Ito, Go;
Banasik, Karina;
Becker, Thomas;
Bokelmann, Frank;
Brunak, Søren;
Buch, Stephan;
Clausnitzer, Hartmut;
Datz, Christian.
(2021)
Genome-wide analysis of 944 133 individuals provides insights into the etiology of haemorrhoidal disease.
Gut.
volum 70 (8).
Academic article
-
Børte, Sigrid;
Zwart, John-Anker;
Skogholt, Anne Heidi;
Gabrielsen, Maiken Elvestad;
Thomas, Laurent;
Fritsche, Lars;
Surakke, Ida;
Nielsen, Jonas B.;
Zhou, Wei;
Wolford, Brooke;
Vigeland, Magnus Dehli;
Hagen, Knut;
Kristoffersen, Espen Saxhaug;
Nyholt, Dale R;
Chasman, Daniel I;
Brumpton, Ben Michael;
Willer, Christen;
Winsvold, Bendik K S.
(2020)
Mitochondrial genome-wide association study of migraine – the HUNT Study.
Cephalalgia.
volum 40 (6).
Academic article
-
Johnsen, Marianne Bakke;
Magnusson, Karin;
Børte, Sigrid;
Gabrielsen, Maiken Elvestad;
Winsvold, Bendik K S;
Skogholt, Anne Heidi;
Thomas, Laurent;
Storheim, Kjersti;
Hveem, Kristian;
Zwart, John-Anker.
(2020)
Development and validation of a prediction model for incident hand osteoarthritis in the HUNT study.
Osteoarthritis and Cartilage.
volum 28 (7).
Academic article
-
Klarin, Derek;
Verma, Shefali Setia;
Judy, Renae;
Dikilitas, Ozan;
Wolford, Brooke N.;
Paranjpe, Ishan;
Levin, Michael G.;
Pan, Cuiping;
Tcheandjieu, Catherine;
Spin, Joshua M.;
Lynch, Julie;
Assimes, Themistocles L;
Nyrønning, Linn Ålstedt;
Mattsson, Erney;
Edwards, Todd L.;
Denny, Josh C.;
Larson, Eric B.;
Lee, Ming Ta Michael;
Carrell, David S..
(2020)
Genetic Architecture of Abdominal Aortic Aneurysm in the Million Veteran Program.
Circulation.
volum 142 (17).
Academic article
-
Løset, Mari;
Thomas, Laurent;
Brumpton, Ben Michael;
Wolford, Brooke N.;
Holmen, Oddgeir;
Luetge, Almut;
Skogholt, Anne Heidi;
Modalsli, Ellen Heilmann;
Solvin, Åshild Øksnevad;
Fritsche, Lars;
Nielsen, Jonas Bille;
Zhou, Wei;
Gabrielsen, Maiken Elvestad;
Saunes, Marit;
Willer, Cristen;
Hveem, Kristian.
(2019)
Genome-wide association study of psoriasis suggests a new risk locus on chromosome 10: The HUNT Study.
Forum for Nordic Dermato-Venereology.
volum 24 (2).
Abstract
-
Stracquadanio, Giovanni;
Wang, Xuting;
Wallace, Marsha D;
Grawenda, Anna M.;
Zhang, Ping;
Hewitt, Juliet;
Zeron-Medina, Jorge;
Castro-Giner, Francesc;
Tomlinson, Ian P;
Goding, Colin R.;
Cygan, Kamil J;
Fairbrother, William G;
Thomas, Laurent;
Sætrom, Pål;
Gemignani, Federica;
Landi, Stefano;
Schuster-Böckler, Benjamin;
Bell, Douglas A;
Bond, Gareth L..
(2016)
The importance of p53 pathway genetics in inherited and somatic cancer genomes.
Nature Reviews Cancer.
volum 16 (4).
Academic article
-
Razick, Sabry;
Mocnik, Rok;
Thomas, Laurent;
Ryeng, Einar;
Drabløs, Finn;
Sætrom, Pål.
(2014)
The eGenVar data management system--cataloguing and sharing sensitive data and metadata for the life sciences.
Database: The Journal of Biological Databases and Curation.
Academic article
-
Thomas, Laurent;
Sætrom, Pål.
(2014)
Circular RNAs are depleted of polymorphisms at microRNA binding sites.
Bioinformatics.
volum 30 (16).
Academic article
-
Thomas, Laurent;
Sætrom, Pål.
(2012)
Single Nucleotide Polymorphisms Can Create Alternative Polyadenylation Signals and Affect Gene Expression through Loss of MicroRNA-Regulation.
PLoS Computational Biology.
volum 8 (8).
Academic article
-
Thomas, Laurent;
Saito, Takaya;
Sætrom, Pål.
(2011)
Inferring causative variants in microRNA target sites.
Nucleic Acids Research (NAR).
volum 39 (16).
Academic article
-
Sætrom, Pål;
Biesinger, Jacob;
Li, Sierra M.;
Smith, David;
Thomas, Laurent Francois;
Majzoub, Karim;
Rivas, Guillermo E.;
Alluin, Jessica;
Rossi, John J.;
Krontiris, Theodore G.;
Weitzel, Jeffrey;
Daly, Mary B.;
Benson, Al B.;
Kirkwood, John M.;
O'Dwyer, Peter J.;
Sutphen, Rebecca;
Stewart, James A.;
Johnson, David;
Larson, Garrett P..
(2009)
A Risk Variant in an miR-125b Binding Site in BMPR1B Is Associated with Breast Cancer Pathogenesis.
Cancer Research.
volum 69 (18).
Academic article
Report
-
Thomas, Laurent.
(2012)
Effects of single-nucleotide polymorphisms on microRNA-based gene regulation and their association with disease.
2012. ISBN 978-82-471-3932-5. Doktoravhandlinger ved NTNU (2012:307).
Doctoral dissertation
Media
2022
-
PosterLund-Hanssen, Charlotte; Olsen, Lene Christin; Thomas, Laurent Francois; Sætrom, Pål. (2022) The Conserved Expression of Long Non-Coding RNAs in the Entorhinal Cortex During Postnatal Development. 8th Annual NORBIS Conference . NORBIS, MedBioInfo; Rosendal. 2022-10-24 - 2022-10-28.
-
Academic lectureLøset, Mari; Thomas, Laurent Francois; Brumpton, Ben Michael; Modalsli, Ellen Heilmann; Gabrielsen, Maiken Elvestad; Solvin, Åshild Øksnevad; Saunes, Marit; Willer, Cristen; Åsvold, Bjørn Olav; Hveem, Kristian; Dand, Nick; Tsoi, Lam C; Nair, Rajan P.; Smith, Catherine; Barker, Jonathan N; Simpson, Melanie Rae; Elder, James E.; The International Psoriasis, Gwas Consortium. (2022) Discovering novel genes and causal relationships for psoriasis: The HUNT study. 35th Nordic Congres of Dermatology and Venereology . Nordic Dermatology Association; København. 2022-04-19 - 2022-04-22.
-
PosterSolvin, Åshild Øksnevad; Bjarkø, Vera Vik; Thomas, Laurent Francois; Berropsi, Patricia; Hveem, Kristian; Saunes, Marit; Åsvold, Bjørn Olav; Løset, Mari. (2022) Body composition, cardiometabolic risk factors and comorbidities in psoriasis and the effect of HLA-C*06:02 status in a general population. 51st Annual ESDR meeting . European Society for Dermatological Research; Amsterdam. 2022-09-28 - 2022-10-01.
-
PosterØvretveit, Karsten; Ingeström, Emma Maria Lovisa; Spitieris, Michail; Tragante, Vinicius; Wade, Kaitlin Hazel; Thomas, Laurent Francois; Wolford, Brooke Nichole; Wisløff, Ulrik; Gudbjartsson, Daníel Fannar; Hólm, Hilma; Stefánsson, Kári; Brumpton, Ben Michael; Hveem, Kristian. (2022) Polygenic predictions and interactions in hypertension. K.G. Jebsen for Genetic Epidemiology Symposium ; 2022-11-29 - 2022-11-30.
-
Academic lectureØvretveit, Karsten; Ingeström, Emma Maria Lovisa; Spitieris, Michail; Tragante, Vinicius; Wade, Kaitlin Hazel; Thomas, Laurent Francois; Wolford, Brooke Nichole; Wisløff, Ulrik; Gudbjartsson, Daníel Fannar; Hólm, Hilma; Stefánsson, Kári; Brumpton, Ben Michael; Hveem, Kristian. (2022) Polygenic predictions and interactions in hypertension. Exercise in Medicine . Cardiac Exercise Research Group (CERG); Trondheim. 2022-12-14 - 2022-12-15.
2019
-
Academic lectureLøset, Mari; Thomas, Laurent; Brumpton, Ben Michael; Wolford, Brooke N.; Holmen, Oddgeir; Luetge, Almut; Skogholt, Anne Heidi; Modalsli, Ellen Heilmann; Solvin, Åshild Øksnevad; Fritsche, Lars; Nielsen, Jonas Bille; Zhou, Wei; Gabrielsen, Maiken Elvestad; Saunes, Marit; Willer, Cristen; Hveem, Kristian. (2019) Genome-wide association study of psoriasis suggests a new risk locus on chromosome 10: The HUNT Study. The 34th Nordic Congress of Dermatology & Venereology ; Gøteborg. 2019-05-08 - 2019-05-10.
2018
-
PosterBlankvoort, Stefan; Thomas, Laurent; Witter, Menno; Sætrom, Pål; cotney, Justin; Kentros, Clifford. (2018) The marked diversity of unique cortical enhancers enables neuron-specific tools by Enhancer-Driven Gene Expression (EDGE). FENS 2018 . Federation of European Neuroscience; Berlin. 2018-07-07 - 2018-07-11.
2017
-
Academic lectureThomas, Laurent. (2017) SNPs affecting microRNA-based gene regulation. Mandagsmøte IKM . IKM, NTNU; 2017-04-03 - 2017-04-03.
-
Academic lectureThomas, Laurent. (2017) SNPs affecting microRNA-based gene regulation. Jebsen center for genetic epidemiology meeting . Jebsen center for genetic epidemiology, NTNU; 2017-03-27 - 2017-03-27.
2015
-
Academic lectureThomas, Laurent. (2015) Detection of circular RNAs in Rat. Mandagsmøte IKM . IKM, NTNU; 2015-11-02 - 2015-11-02.
2014
-
Academic lectureThomas, Laurent. (2014) Circular RNAs are depleted of polymorphisms at microRNA binding sites. Mandagsmøte IKM . IKM, NTNU; 2014-12-01 - 2014-12-01.
2013
-
Academic lectureSætrom, Pål; Thomas, Laurent. (2013) Finding SNPs that affect microRNA regulation. 10th International RNAi, MicroRNAs & Single Cell Biology – 2013 Meeting ; 2013-05-01 - 2013-05-02.
-
Academic lectureThomas, Laurent. (2013) Single nucleotide polymorphisms in microRNA Binding Sites of circular RNAs. Systems Biology meetings at NTNU ; 2013-10-11 - 2013-10-11.
2012
-
Academic lectureThomas, Laurent. (2012) Effects of single-nucleotide polymorphisms on microRNA-based gene regulation. Systems Biology meetings at NTNU ; 2012-10-05 - 2012-10-05.
2011
-
Academic lectureThomas, Laurent. (2011) Identifying disease-causative variants in microRNA target sites. Mandagsmøte IKM . Institutt for kreftforskning og molekylær medisin, NTNU; Trondheim. 2011-03-21 - 2011-03-21.
-
Academic lectureThomas, Laurent. (2011) Identifying disease-causative variants in microRNA target sites. eGenVar møte . Pål Sætrom; Trondheim. 2011-03-25 - 2011-03-25.
-
Academic lectureThomas, Laurent. (2011) Identifying disease-causative variants in microRNA target sites. Bioinformatics for Young Scientists 2011 ; Ullensvang, Hardanger. 2011-03-16 - 2011-03-18.
-
Academic lectureThomas, Laurent. (2011) SNPs can create alternative polyadenylation signals and affect gene expression through loss of microRNA-regulation. Systems Biology meetings at NTNU . NTNU bioinformatics & Systems biology groups; Trondheim. 2011-09-30 - 2011-09-30.
2010
-
Academic lectureThomas, Laurent Francois. (2010) Identifying disease-causative variants in microRNA target sites. Systems Biology meetings at NTNU . NTNU bioinformatics & Systems biology groups; Trondheim. 2010-10-22 - 2010-10-22.
-
PosterThomas, Laurent Francois; Saito, Takaya; Sætrom, Pål. (2010) Identifying causative variants in microRNA target sites. RECOMB Computational Cancer Biology . Norwegian Radium Hospital / University of Oslo; Oslo. 2010-06-24 - 2010-06-25.