Laurent Thomas
About
Researcher at the Unit for Molecular Biology, in the group for Bioinformatics and Gene Regulation, and in the K.G. Jebsen Center for Genetic Epidemiology.
Received a Ph.D. in bioinformatics and trained as a postdoctoral scientist at the Norwegian University of Science and Technology (NTNU), Trondheim. His research interests focus on gene regulation, particularly on single nucleotide polymorphisms, alternative polyadenylation and non-coding RNAs such as microRNAs and circular RNAs, but also genetic variants such as Single Nucleotide Polymorphisms (SNP), particulary SNP funcitonal changes, Genome-wide association studies (GWAS) and genotype quality control (QC).
Publications
2024
-
Potenza, Maria Letizia;
Blankvoort, Stefan Matthias Adriaan;
Carvalho, Miguel;
Grimstvedt, Joachim Schweder;
Di Maria, Valentina;
Moan, Kristian Magnus.
(2024)
Generation of an enhancer-driven gene expression viral tool specific to dentate granule cell-types through direct hippocampal injection.
Frontiers in Neuroscience
Academic article
-
Moksnes, Marta R.;
Hansen, Ailin F.;
Wolford, Brooke N.;
Thomas, Laurent F.;
Rasheed, Humaira;
Simic, Anica.
(2024)
A genome-wide association study provides insights into the genetic etiology of 57 essential and non-essential trace elements in humans.
Communications Biology
Academic article
-
Hernandez-Cordero, Ariana;
Thomas, Laurent Francois;
Smail, Alice;
Lim, Zhao Qin;
Saklatvala, Jake R.;
Chung, Raymond.
(2024)
A genome-wide meta-analysis of palmoplantar pustulosis implicates T<inf>H</inf>2 responses and cigarette smoking in disease pathogenesis.
Journal of Allergy and Clinical Immunology
Academic article
-
Scholz, Markus;
Horn, Katrin;
pott, janne;
Wuttke, Matthias;
Hallan, Stein Ivar;
Schlosser, Pascal.
(2024)
X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements.
Nature Communications
Academic article
-
Øvretveit, Karsten;
Ingeström, Emma Maria Lovisa;
Spitieris, Michail;
Tragante, Vinicius;
Thomas, Laurent Francois;
Steinsland, Ingelin.
(2024)
Polygenic interactions with environmental exposures in blood pressure regulation: the HUNT study.
Journal of the American Heart Association (JAHA)
Academic article
2023
-
McSweeney, Sheila Mary;
Saklatvala, Jake;
Rispoli, Rossella;
Ganier, Clarisse;
Woszczek, Grzegorz;
Thomas, Laurent Francois.
(2023)
Genome-wide meta-analysis implicates variation affecting mast cell biology in urticaria.
Journal of Allergy and Clinical Immunology
Academic article
-
Surakka, Ida;
Wolford, Brooke Nichole;
Ritchie, Scott C.;
Hornsby, Whitney E.;
Sutton, Nadia R.;
Gabrielsen, Maiken Elvestad.
(2023)
Sex-Specific Survival Bias and Interaction Modeling in Coronary Artery Disease Risk Prediction.
Circulation: Genomic and precision medicine
Academic article
-
Solvin, Åshild Øksnevad;
Bjarkø, Vera Vik;
Thomas, Laurent Francois;
Berrospi, Patricia;
Hveem, Kristian;
Saunes, Marit.
(2023)
Body Composition, Cardiometabolic Risk Factors and Comorbidities in Psoriasis and the Effect of HLA-C*06:02 Status: The HUNT Study, Norway.
Acta Dermato-Venereologica
Academic article
-
Øvretveit, Karsten;
Ingeström, Emma Maria Lovisa;
Spitieris, Michail;
Tragante, Vinicius;
Wade, Kaitlin Hazel;
Thomas, Laurent Francois.
(2023)
Polygenic risk scores associate with blood pressure traits across the lifespan.
European Journal of Preventive Cardiology (EJPC)
Academic article
-
Budu-Aggrey, Ashley;
Kilanowski, Anna;
Sobczyk, Maria K.;
Shringarpure, Suyash S.;
Mitchell, Ruth;
Reis, Kadri.
(2023)
European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation.
Nature Communications
Academic article
-
Winsvold, Bendik Kristoffer Slagsvold;
Harder, Aster V. E.;
Ran, Caroline;
Chalmer, Mona A.;
Dalmasso, Maria Carolina;
Ferkingstad, Egil.
(2023)
Cluster Headache Genomewide Association Study and Meta-Analysis Identifies Eight Loci and Implicates Smoking as Causal Risk Factor.
Annals of Neurology
Academic article
-
Jacobsen, Kaya Kvarme;
Børte, Sigrid;
Laborie, Lene Bjerke;
Kristiansen, Hege;
Schäfer, Annette;
Martinsen, Amy.
(2023)
COL11A1 is associated with developmental dysplasia of the hip and secondary osteoarthritis in the HUNT study.
Osteoarthritis and Cartilage Open
Academic article
2022
-
Hautakangas, Heidi;
Winsvold, Bendik K S;
Ruotsalainen, Sanni;
Bjornsdottir, Gyda;
Harder, Aster V. E.;
Kogelman, Lisette J. A..
(2022)
Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles .
Nature Genetics
Academic article
-
Gorski, Mathias;
Rasheed, Humaira;
Teumer, Alexander;
Thomas, Laurent;
Graham, Sarah E.;
Sveinbjornsson, Gardar.
(2022)
Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies.
Kidney International
Academic article
-
Winkler, Thomas W.;
Rasheed, Humaira;
Teumer, Alexander;
Gorski, Mathias;
Rowan, Bryce X.;
Stanzick, Kira J..
(2022)
Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals.
Communications Biology
Academic article
-
Brumpton, Ben Michael;
Graham, Sarah;
Surakka, Ida;
Skogholt, Anne Heidi;
Løset, Mari;
Fritsche, Lars G..
(2022)
The HUNT study: A population-based cohort for genetic research.
Cell Genomics
Academic article
-
Hartley, April;
Sanderson, Eleanor;
Granell, Raquel;
Paternoster, Lavinia;
Zheng, Jie;
Smith, George Davey.
(2022)
Using multivariable Mendelian randomization to estimate the causal effect of bone mineral density on osteoarthritis risk, independently of body mass index.
International Journal of Epidemiology
Academic article
-
Mishra, Aniket;
Malik, Rainer;
Hachiya, Tsuyoshi;
Jürgenson, Tuuli;
Namba, Shinichi;
Posner, Daniel C..
(2022)
Publisher Correction: Stroke genetics informs drug discovery and risk prediction across ancestries.
Nature
Errata
-
Mars, Nina;
Kerminen, Sini;
Feng, Yen-Chen A.;
Kanai, Masahiro;
Läll, Kristi;
Thomas, Laurent Francois.
(2022)
Genome-wide risk prediction of common diseases across ancestries in one million people.
Cell Genomics
Academic article
-
Wightman, Douglas P.;
Jansen, Iris E.;
Savage, Jeanne E.;
Shadrin, Alexey;
Bahrami, Shahram;
Holland, Dominic.
(2022)
Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer’s disease (Nature Genetics, (2021), 53, 9, (1276-1282), 10.1038/s41588-021-00921-z).
Nature Genetics
Errata
-
Solvin, Åshild Øksnevad;
Bjarkø, Vera Vik;
Thomas, Laurent Francois;
Berrospi, Patricia;
Hveem, Kristian;
Saunes, Marit.
(2022)
Body composition, cardiometabolic risk factors and comorbidities in psoriasis and the effect of HLA-C*06:02 status in a general population.
Journal of Investigative Dermatology
Abstract
-
Løset, Mari;
Thomas, Laurent Francois;
Brumpton, Ben Michael;
Modalsli, Ellen Heilmann;
Gabrielsen, Maiken Elvestad;
Solvin, Åshild Øksnevad.
(2022)
Discovering novel genes and causal relationships for psoriasis: The HUNT study.
Acta Dermato-Venereologica
Abstract
-
Mishra, Aniket;
Malik, Rainer;
Hachiya, Tsuyoshi;
Jürgenson, Tuuli;
Namba, Shinichi;
Posner, Daniel C..
(2022)
Stroke genetics informs drug discovery and risk prediction across ancestries.
Nature
Academic article
-
Bahrami, Shahram;
Hindley, Guy Frederick Lanyon;
Winsvold, Bendik K S;
O'Connell, Kevin Sean;
Frei, Oleksandr;
Shadrin, Alexey.
(2022)
Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools.
Brain
Academic article
-
Mitchell, Brittany L.;
Saklatvala, Jake R.;
Dand, Nick;
Hagenbeek, Fiona A.;
Li, Xin;
Min, Josine L..
(2022)
Genome-wide association meta-analysis identifies 29 new acne susceptibility loci.
Nature Communications
Academic article
2021
-
Wightman, Douglas P.;
Jansen, Iris E.;
Savage, Jeanne E.;
Shadrin, Alexey;
Bahrami, Shahram;
Holland, Dominic.
(2021)
A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease.
Nature Genetics
Academic article
-
Johnsen, Marianne Bakke;
Magnusson, Karin;
Børte, Sigrid;
Gabrielsen, Maiken Elvestad;
Winsvold, Bendik K S;
Skogholt, Anne Heidi.
(2021)
Response to Letter to the Editor: ‘Comments on the paper presenting prediction models for incident hand OA in the HUNT study’.
Osteoarthritis and Cartilage
Letter to the editor
-
Boer, Cindy G.;
Hatzikotoulas, Konstantinos;
Southam, Lorraine;
Stefánsdóttir, Lilja;
Almeida, Rodrigo Coutinho de;
Zhang, Yanfei.
(2021)
Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations.
Cell
Academic article
-
Rasheed, Humaira;
Zheng, Jie;
Rees, Jessica;
Sanderson, Eleanor;
Thomas, Laurent;
Richardson, Tom G..
(2021)
The causal effects of serum lipids and apolipoproteins on kidney function: Multivariable and bidirectional Mendelian-randomization analyses.
International Journal of Epidemiology
Academic article
-
Zheng, Thenghao;
Ellinghaus, David;
Juzenas, Simonas;
Cossais, François;
Burmeister, Greta;
Mayr, Gabriele.
(2021)
Genome-wide analysis of 944 133 individuals provides insights into the etiology of haemorrhoidal disease.
Gut
Academic article
-
Stanzick, Kira J.;
Li, Yong;
Schlosser, Pascal;
Gorski, Mathias;
Wuttke, Matthias;
Thomas, Laurent.
(2021)
Discovery and prioritization of variants and genes for kidney function in >1.2 million individuals.
Nature Communications
Academic article
-
Rogne, Tormod;
Liyanarachi, Kristin Vardheim;
Rasheed, Humaira;
Thomas, Laurent;
Flatby, Helene Marie;
Stenvik, Jørgen.
(2021)
GWAS Identifies LINC01184/SLC12A2 as a Risk Locus for Skin and Soft Tissue Infections.
Journal of Investigative Dermatology
Academic article
-
Zheng, Jie;
Zhang, Yuemiao;
Rasheed, Humaira;
Walker, Venexia M.;
Sugawara, Yuka;
Li, Jiachen.
(2021)
Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease.
International Journal of Epidemiology
Academic article
-
Winsvold, Bendik K S;
Kitsos, Ioannis;
Thomas, Laurent;
Skogholt, Anne Heidi;
Gabrielsen, Maiken Elvestad;
Zwart, John Anker Henrik.
(2021)
Genome-Wide Association Study of 2,093 Cases With Idiopathic Polyneuropathy and 445,256 Controls Identifies First Susceptibility Loci.
Frontiers in Neurology
Academic article
-
Freidin, Maxim B.;
Tsepilov, Yakov A.;
Stanaway, Ian B.;
Meng, Weihua;
Hayward, Caroline;
Smith, Blair H..
(2021)
Sex- and age-specific genetic analysis of chronic back pain.
Pain
Academic article
-
Moksnes, Marta Riise;
Røsjø, Helge;
Richmond, Anne;
Lyngbakken, Magnus N;
Graham, Sarah E;
Hansen, Ailin Falkmo.
(2021)
Genome-wide association study of cardiac troponin i in the general population.
Human Molecular Genetics
Academic article
-
Rahman, Shafiqur;
Winsvold, Bendik K S;
Chavez, Sergio;
Børte, Sigrid;
Tsepilov, Vakov;
Sharapov, Sodbo Zh.
(2021)
Genome-wide association study identifies RNF123 locus as associated with chronic widespread musculoskeletal pain.
Annals of the Rheumatic Diseases
Academic article
-
Khoury, Samar;
Parisien, Marc;
Thompson, Scott J.;
Vachon-Presseau, Etienne;
Roy, Mathieu;
Mitchell, Amy.
(2021)
Genome-wide analysis identifies impaired axonogenesis in chronic overlapping pain conditions.
Brain
Academic article
-
Harder, Aster V.E.;
Winsvold, Bendik K S;
Noordam, Raymond;
Vijfhuizen, Lisanne S.;
Børte, Sigrid;
Kogelman, Lisette J.A..
(2021)
Genetic Susceptibility Loci in Genomewide Association Study of Cluster Headache.
Annals of Neurology
Academic article
-
Flatby, Helene Marie;
Rasheed, Humaira;
Ravi, Anuradha;
Thomas, Laurent;
Liyanarachi, Kristin Vardheim;
Afset, Jan Egil.
(2021)
Risk of lower respiratory tract infections: a genome-wide association study with Mendelian randomization analysis in three independent European populations.
Clinical Microbiology and Infection (CMI)
Academic article
2020
-
Johnsen, Marianne Bakke;
Magnusson, Karin;
Børte, Sigrid;
Gabrielsen, Maiken Elvestad;
Winsvold, Bendik K S;
Skogholt, Anne Heidi.
(2020)
Development and validation of a prediction model for incident hand
osteoarthritis in the HUNT study.
Osteoarthritis and Cartilage
Academic article
-
Børte, Sigrid;
Zwart, John-Anker;
Skogholt, Anne Heidi;
Gabrielsen, Maiken Elvestad;
Thomas, Laurent;
Fritsche, Lars.
(2020)
Mitochondrial genome-wide association study of migraine – the HUNT Study .
Cephalalgia
Academic article
-
Klarin, Derek;
Verma, Shefali Setia;
Judy, Renae;
Dikilitas, Ozan;
Wolford, Brooke N.;
Paranjpe, Ishan.
(2020)
Genetic Architecture of Abdominal Aortic Aneurysm in the Million Veteran Program.
Circulation
Academic article
2019
-
Løset, Mari;
Thomas, Laurent;
Brumpton, Ben Michael;
Wolford, Brooke N.;
Holmen, Oddgeir;
Luetge, Almut.
(2019)
Genome-wide association study of psoriasis suggests a new risk locus on chromosome 10: The HUNT Study.
Forum for Nordic Dermato-Venereology
Abstract
2016
-
Stracquadanio, Giovanni;
Wang, Xuting;
Wallace, Marsha D;
Grawenda, Anna M.;
Zhang, Ping;
Hewitt, Juliet.
(2016)
The importance of p53 pathway genetics in inherited and somatic cancer genomes.
Nature Reviews Cancer
Academic article
2014
-
Thomas, Laurent;
Sætrom, Pål.
(2014)
Circular RNAs are depleted of polymorphisms at microRNA binding sites.
Bioinformatics
Academic article
-
Razick, Sabry;
Mocnik, Rok;
Thomas, Laurent;
Ryeng, Einar;
Drabløs, Finn;
Sætrom, Pål.
(2014)
The eGenVar data management system--cataloguing and sharing sensitive data and metadata for the life sciences.
Database: The Journal of Biological Databases and Curation
Academic article
2012
-
Thomas, Laurent;
Sætrom, Pål.
(2012)
Single Nucleotide Polymorphisms Can Create Alternative Polyadenylation Signals and Affect Gene Expression through Loss of MicroRNA-Regulation.
PLoS Computational Biology
Academic article
-
Thomas, Laurent.
(2012)
Effects of single-nucleotide polymorphisms on microRNA-based gene regulation and their association with disease.
Doktoravhandlinger ved NTNU (2012:307)
Doctoral dissertation
2011
-
Thomas, Laurent;
Saito, Takaya;
Sætrom, Pål.
(2011)
Inferring causative variants in microRNA target sites.
Nucleic Acids Research (NAR)
Academic article
2009
-
Sætrom, Pål;
Biesinger, Jacob;
Li, Sierra M.;
Smith, David;
Thomas, Laurent Francois;
Majzoub, Karim.
(2009)
A Risk Variant in an miR-125b Binding Site in BMPR1B Is Associated with Breast Cancer Pathogenesis.
Cancer Research
Academic article
Journal publications
-
Potenza, Maria Letizia;
Blankvoort, Stefan Matthias Adriaan;
Carvalho, Miguel;
Grimstvedt, Joachim Schweder;
Di Maria, Valentina;
Moan, Kristian Magnus.
(2024)
Generation of an enhancer-driven gene expression viral tool specific to dentate granule cell-types through direct hippocampal injection.
Frontiers in Neuroscience
Academic article
-
Moksnes, Marta R.;
Hansen, Ailin F.;
Wolford, Brooke N.;
Thomas, Laurent F.;
Rasheed, Humaira;
Simic, Anica.
(2024)
A genome-wide association study provides insights into the genetic etiology of 57 essential and non-essential trace elements in humans.
Communications Biology
Academic article
-
Hernandez-Cordero, Ariana;
Thomas, Laurent Francois;
Smail, Alice;
Lim, Zhao Qin;
Saklatvala, Jake R.;
Chung, Raymond.
(2024)
A genome-wide meta-analysis of palmoplantar pustulosis implicates T<inf>H</inf>2 responses and cigarette smoking in disease pathogenesis.
Journal of Allergy and Clinical Immunology
Academic article
-
Scholz, Markus;
Horn, Katrin;
pott, janne;
Wuttke, Matthias;
Hallan, Stein Ivar;
Schlosser, Pascal.
(2024)
X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements.
Nature Communications
Academic article
-
Øvretveit, Karsten;
Ingeström, Emma Maria Lovisa;
Spitieris, Michail;
Tragante, Vinicius;
Thomas, Laurent Francois;
Steinsland, Ingelin.
(2024)
Polygenic interactions with environmental exposures in blood pressure regulation: the HUNT study.
Journal of the American Heart Association (JAHA)
Academic article
-
McSweeney, Sheila Mary;
Saklatvala, Jake;
Rispoli, Rossella;
Ganier, Clarisse;
Woszczek, Grzegorz;
Thomas, Laurent Francois.
(2023)
Genome-wide meta-analysis implicates variation affecting mast cell biology in urticaria.
Journal of Allergy and Clinical Immunology
Academic article
-
Surakka, Ida;
Wolford, Brooke Nichole;
Ritchie, Scott C.;
Hornsby, Whitney E.;
Sutton, Nadia R.;
Gabrielsen, Maiken Elvestad.
(2023)
Sex-Specific Survival Bias and Interaction Modeling in Coronary Artery Disease Risk Prediction.
Circulation: Genomic and precision medicine
Academic article
-
Solvin, Åshild Øksnevad;
Bjarkø, Vera Vik;
Thomas, Laurent Francois;
Berrospi, Patricia;
Hveem, Kristian;
Saunes, Marit.
(2023)
Body Composition, Cardiometabolic Risk Factors and Comorbidities in Psoriasis and the Effect of HLA-C*06:02 Status: The HUNT Study, Norway.
Acta Dermato-Venereologica
Academic article
-
Øvretveit, Karsten;
Ingeström, Emma Maria Lovisa;
Spitieris, Michail;
Tragante, Vinicius;
Wade, Kaitlin Hazel;
Thomas, Laurent Francois.
(2023)
Polygenic risk scores associate with blood pressure traits across the lifespan.
European Journal of Preventive Cardiology (EJPC)
Academic article
-
Budu-Aggrey, Ashley;
Kilanowski, Anna;
Sobczyk, Maria K.;
Shringarpure, Suyash S.;
Mitchell, Ruth;
Reis, Kadri.
(2023)
European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation.
Nature Communications
Academic article
-
Winsvold, Bendik Kristoffer Slagsvold;
Harder, Aster V. E.;
Ran, Caroline;
Chalmer, Mona A.;
Dalmasso, Maria Carolina;
Ferkingstad, Egil.
(2023)
Cluster Headache Genomewide Association Study and Meta-Analysis Identifies Eight Loci and Implicates Smoking as Causal Risk Factor.
Annals of Neurology
Academic article
-
Jacobsen, Kaya Kvarme;
Børte, Sigrid;
Laborie, Lene Bjerke;
Kristiansen, Hege;
Schäfer, Annette;
Martinsen, Amy.
(2023)
COL11A1 is associated with developmental dysplasia of the hip and secondary osteoarthritis in the HUNT study.
Osteoarthritis and Cartilage Open
Academic article
-
Hautakangas, Heidi;
Winsvold, Bendik K S;
Ruotsalainen, Sanni;
Bjornsdottir, Gyda;
Harder, Aster V. E.;
Kogelman, Lisette J. A..
(2022)
Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles .
Nature Genetics
Academic article
-
Gorski, Mathias;
Rasheed, Humaira;
Teumer, Alexander;
Thomas, Laurent;
Graham, Sarah E.;
Sveinbjornsson, Gardar.
(2022)
Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies.
Kidney International
Academic article
-
Winkler, Thomas W.;
Rasheed, Humaira;
Teumer, Alexander;
Gorski, Mathias;
Rowan, Bryce X.;
Stanzick, Kira J..
(2022)
Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals.
Communications Biology
Academic article
-
Brumpton, Ben Michael;
Graham, Sarah;
Surakka, Ida;
Skogholt, Anne Heidi;
Løset, Mari;
Fritsche, Lars G..
(2022)
The HUNT study: A population-based cohort for genetic research.
Cell Genomics
Academic article
-
Hartley, April;
Sanderson, Eleanor;
Granell, Raquel;
Paternoster, Lavinia;
Zheng, Jie;
Smith, George Davey.
(2022)
Using multivariable Mendelian randomization to estimate the causal effect of bone mineral density on osteoarthritis risk, independently of body mass index.
International Journal of Epidemiology
Academic article
-
Mishra, Aniket;
Malik, Rainer;
Hachiya, Tsuyoshi;
Jürgenson, Tuuli;
Namba, Shinichi;
Posner, Daniel C..
(2022)
Publisher Correction: Stroke genetics informs drug discovery and risk prediction across ancestries.
Nature
Errata
-
Mars, Nina;
Kerminen, Sini;
Feng, Yen-Chen A.;
Kanai, Masahiro;
Läll, Kristi;
Thomas, Laurent Francois.
(2022)
Genome-wide risk prediction of common diseases across ancestries in one million people.
Cell Genomics
Academic article
-
Wightman, Douglas P.;
Jansen, Iris E.;
Savage, Jeanne E.;
Shadrin, Alexey;
Bahrami, Shahram;
Holland, Dominic.
(2022)
Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer’s disease (Nature Genetics, (2021), 53, 9, (1276-1282), 10.1038/s41588-021-00921-z).
Nature Genetics
Errata
-
Solvin, Åshild Øksnevad;
Bjarkø, Vera Vik;
Thomas, Laurent Francois;
Berrospi, Patricia;
Hveem, Kristian;
Saunes, Marit.
(2022)
Body composition, cardiometabolic risk factors and comorbidities in psoriasis and the effect of HLA-C*06:02 status in a general population.
Journal of Investigative Dermatology
Abstract
-
Løset, Mari;
Thomas, Laurent Francois;
Brumpton, Ben Michael;
Modalsli, Ellen Heilmann;
Gabrielsen, Maiken Elvestad;
Solvin, Åshild Øksnevad.
(2022)
Discovering novel genes and causal relationships for psoriasis: The HUNT study.
Acta Dermato-Venereologica
Abstract
-
Mishra, Aniket;
Malik, Rainer;
Hachiya, Tsuyoshi;
Jürgenson, Tuuli;
Namba, Shinichi;
Posner, Daniel C..
(2022)
Stroke genetics informs drug discovery and risk prediction across ancestries.
Nature
Academic article
-
Bahrami, Shahram;
Hindley, Guy Frederick Lanyon;
Winsvold, Bendik K S;
O'Connell, Kevin Sean;
Frei, Oleksandr;
Shadrin, Alexey.
(2022)
Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools.
Brain
Academic article
-
Mitchell, Brittany L.;
Saklatvala, Jake R.;
Dand, Nick;
Hagenbeek, Fiona A.;
Li, Xin;
Min, Josine L..
(2022)
Genome-wide association meta-analysis identifies 29 new acne susceptibility loci.
Nature Communications
Academic article
-
Wightman, Douglas P.;
Jansen, Iris E.;
Savage, Jeanne E.;
Shadrin, Alexey;
Bahrami, Shahram;
Holland, Dominic.
(2021)
A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease.
Nature Genetics
Academic article
-
Johnsen, Marianne Bakke;
Magnusson, Karin;
Børte, Sigrid;
Gabrielsen, Maiken Elvestad;
Winsvold, Bendik K S;
Skogholt, Anne Heidi.
(2021)
Response to Letter to the Editor: ‘Comments on the paper presenting prediction models for incident hand OA in the HUNT study’.
Osteoarthritis and Cartilage
Letter to the editor
-
Boer, Cindy G.;
Hatzikotoulas, Konstantinos;
Southam, Lorraine;
Stefánsdóttir, Lilja;
Almeida, Rodrigo Coutinho de;
Zhang, Yanfei.
(2021)
Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations.
Cell
Academic article
-
Rasheed, Humaira;
Zheng, Jie;
Rees, Jessica;
Sanderson, Eleanor;
Thomas, Laurent;
Richardson, Tom G..
(2021)
The causal effects of serum lipids and apolipoproteins on kidney function: Multivariable and bidirectional Mendelian-randomization analyses.
International Journal of Epidemiology
Academic article
-
Zheng, Thenghao;
Ellinghaus, David;
Juzenas, Simonas;
Cossais, François;
Burmeister, Greta;
Mayr, Gabriele.
(2021)
Genome-wide analysis of 944 133 individuals provides insights into the etiology of haemorrhoidal disease.
Gut
Academic article
-
Stanzick, Kira J.;
Li, Yong;
Schlosser, Pascal;
Gorski, Mathias;
Wuttke, Matthias;
Thomas, Laurent.
(2021)
Discovery and prioritization of variants and genes for kidney function in >1.2 million individuals.
Nature Communications
Academic article
-
Rogne, Tormod;
Liyanarachi, Kristin Vardheim;
Rasheed, Humaira;
Thomas, Laurent;
Flatby, Helene Marie;
Stenvik, Jørgen.
(2021)
GWAS Identifies LINC01184/SLC12A2 as a Risk Locus for Skin and Soft Tissue Infections.
Journal of Investigative Dermatology
Academic article
-
Zheng, Jie;
Zhang, Yuemiao;
Rasheed, Humaira;
Walker, Venexia M.;
Sugawara, Yuka;
Li, Jiachen.
(2021)
Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease.
International Journal of Epidemiology
Academic article
-
Winsvold, Bendik K S;
Kitsos, Ioannis;
Thomas, Laurent;
Skogholt, Anne Heidi;
Gabrielsen, Maiken Elvestad;
Zwart, John Anker Henrik.
(2021)
Genome-Wide Association Study of 2,093 Cases With Idiopathic Polyneuropathy and 445,256 Controls Identifies First Susceptibility Loci.
Frontiers in Neurology
Academic article
-
Freidin, Maxim B.;
Tsepilov, Yakov A.;
Stanaway, Ian B.;
Meng, Weihua;
Hayward, Caroline;
Smith, Blair H..
(2021)
Sex- and age-specific genetic analysis of chronic back pain.
Pain
Academic article
-
Moksnes, Marta Riise;
Røsjø, Helge;
Richmond, Anne;
Lyngbakken, Magnus N;
Graham, Sarah E;
Hansen, Ailin Falkmo.
(2021)
Genome-wide association study of cardiac troponin i in the general population.
Human Molecular Genetics
Academic article
-
Rahman, Shafiqur;
Winsvold, Bendik K S;
Chavez, Sergio;
Børte, Sigrid;
Tsepilov, Vakov;
Sharapov, Sodbo Zh.
(2021)
Genome-wide association study identifies RNF123 locus as associated with chronic widespread musculoskeletal pain.
Annals of the Rheumatic Diseases
Academic article
-
Khoury, Samar;
Parisien, Marc;
Thompson, Scott J.;
Vachon-Presseau, Etienne;
Roy, Mathieu;
Mitchell, Amy.
(2021)
Genome-wide analysis identifies impaired axonogenesis in chronic overlapping pain conditions.
Brain
Academic article
-
Harder, Aster V.E.;
Winsvold, Bendik K S;
Noordam, Raymond;
Vijfhuizen, Lisanne S.;
Børte, Sigrid;
Kogelman, Lisette J.A..
(2021)
Genetic Susceptibility Loci in Genomewide Association Study of Cluster Headache.
Annals of Neurology
Academic article
-
Flatby, Helene Marie;
Rasheed, Humaira;
Ravi, Anuradha;
Thomas, Laurent;
Liyanarachi, Kristin Vardheim;
Afset, Jan Egil.
(2021)
Risk of lower respiratory tract infections: a genome-wide association study with Mendelian randomization analysis in three independent European populations.
Clinical Microbiology and Infection (CMI)
Academic article
-
Johnsen, Marianne Bakke;
Magnusson, Karin;
Børte, Sigrid;
Gabrielsen, Maiken Elvestad;
Winsvold, Bendik K S;
Skogholt, Anne Heidi.
(2020)
Development and validation of a prediction model for incident hand
osteoarthritis in the HUNT study.
Osteoarthritis and Cartilage
Academic article
-
Børte, Sigrid;
Zwart, John-Anker;
Skogholt, Anne Heidi;
Gabrielsen, Maiken Elvestad;
Thomas, Laurent;
Fritsche, Lars.
(2020)
Mitochondrial genome-wide association study of migraine – the HUNT Study .
Cephalalgia
Academic article
-
Klarin, Derek;
Verma, Shefali Setia;
Judy, Renae;
Dikilitas, Ozan;
Wolford, Brooke N.;
Paranjpe, Ishan.
(2020)
Genetic Architecture of Abdominal Aortic Aneurysm in the Million Veteran Program.
Circulation
Academic article
-
Løset, Mari;
Thomas, Laurent;
Brumpton, Ben Michael;
Wolford, Brooke N.;
Holmen, Oddgeir;
Luetge, Almut.
(2019)
Genome-wide association study of psoriasis suggests a new risk locus on chromosome 10: The HUNT Study.
Forum for Nordic Dermato-Venereology
Abstract
-
Stracquadanio, Giovanni;
Wang, Xuting;
Wallace, Marsha D;
Grawenda, Anna M.;
Zhang, Ping;
Hewitt, Juliet.
(2016)
The importance of p53 pathway genetics in inherited and somatic cancer genomes.
Nature Reviews Cancer
Academic article
-
Thomas, Laurent;
Sætrom, Pål.
(2014)
Circular RNAs are depleted of polymorphisms at microRNA binding sites.
Bioinformatics
Academic article
-
Razick, Sabry;
Mocnik, Rok;
Thomas, Laurent;
Ryeng, Einar;
Drabløs, Finn;
Sætrom, Pål.
(2014)
The eGenVar data management system--cataloguing and sharing sensitive data and metadata for the life sciences.
Database: The Journal of Biological Databases and Curation
Academic article
-
Thomas, Laurent;
Sætrom, Pål.
(2012)
Single Nucleotide Polymorphisms Can Create Alternative Polyadenylation Signals and Affect Gene Expression through Loss of MicroRNA-Regulation.
PLoS Computational Biology
Academic article
-
Thomas, Laurent;
Saito, Takaya;
Sætrom, Pål.
(2011)
Inferring causative variants in microRNA target sites.
Nucleic Acids Research (NAR)
Academic article
-
Sætrom, Pål;
Biesinger, Jacob;
Li, Sierra M.;
Smith, David;
Thomas, Laurent Francois;
Majzoub, Karim.
(2009)
A Risk Variant in an miR-125b Binding Site in BMPR1B Is Associated with Breast Cancer Pathogenesis.
Cancer Research
Academic article
Report
-
Thomas, Laurent.
(2012)
Effects of single-nucleotide polymorphisms on microRNA-based gene regulation and their association with disease.
Doktoravhandlinger ved NTNU (2012:307)
Doctoral dissertation
Knowledge Transfer
2024
-
Academic lectureAlam, Mohammad Sayeef; Hjort, Rebecka Louise; Thomas, Laurent Francois; Brumpton, Ben Michael; Hveem, Kristian; Lundin, Knut. (2024) The IRX1 locus is associated with celiac disease: results from a screened population-based cohort, the HUNT study. The International Society for the Study of Celiac Disease (ISSCD) International Coeliac Disease Symposium (ICDS) 2024 , Sheffield, UK 2024-09-05 - 2024-09-07
-
PosterAlam, Mohammad Sayeef; Hjort, Rebecka Louise; Thomas, Laurent Francois; Brumpton, Ben Michael; Hveem, Kristian; Lundin, Knut. (2024) The IRX1 locus is associated with celiac disease: results from a screened population-based cohort, the HUNT study. Nordic Society of Human Genetics and Precision Medicine (NSHG-PM) Nordic Conference on Future Health (NCFH) 2024 , Trondheim 2024-09-10 - 2024-09-13
2023
-
PosterØvretveit, Karsten; Ingeström, Emma Maria Lovisa; Spitieris, Michail; Tragante, Vinicius; Wade, Kaitlin Hazel; Thomas, Laurent Francois. (2023) Polygenic risk scores predict blood pressure traits across the lifespan. American Society of Human Genetics 2023 Annual Meeting 2023-11-03 -
-
PosterLund-Hanssen, Charlotte; Olsen, Lene Christin; Thomas, Laurent Francois; O'Reilly, Kally; Witter, Menno Peter; Sætrom, Pål. (2023) The Conserved Expression of Long Non-Coding RNAs in the Entorhinal Cortex During Postnatal Development. EMBO Gene Regulatory Mechanisms in Neural Fate Decisions , Alicante, Spain 2023-09-07 - 2023-09-10
2022
-
PosterSolvin, Åshild Øksnevad; Bjarkø, Vera Vik; Thomas, Laurent Francois; Berropsi, Patricia; Hveem, Kristian; Saunes, Marit. (2022) Body composition, cardiometabolic risk factors and comorbidities in psoriasis and the effect of HLA-C*06:02 status in a general population. European Society for Dermatological Research 51st Annual ESDR meeting , Amsterdam 2022-09-28 - 2022-10-01
-
PosterLund-Hanssen, Charlotte; Olsen, Lene Christin; Thomas, Laurent Francois; Sætrom, Pål. (2022) The Conserved Expression of Long Non-Coding RNAs in the Entorhinal Cortex During Postnatal Development. NORBIS, MedBioInfo 8th Annual NORBIS Conference , Rosendal, Norway 2022-10-24 - 2022-10-28
-
Academic lectureLøset, Mari; Thomas, Laurent Francois; Brumpton, Ben Michael; Modalsli, Ellen Heilmann; Gabrielsen, Maiken Elvestad; Solvin, Åshild Øksnevad. (2022) Discovering novel genes and causal relationships for psoriasis: The HUNT study. Nordic Dermatology Association 35th Nordic Congres of Dermatology and Venereology , København 2022-04-19 - 2022-04-22
-
Academic lectureØvretveit, Karsten; Ingeström, Emma Maria Lovisa; Spitieris, Michail; Tragante, Vinicius; Wade, Kaitlin Hazel; Thomas, Laurent Francois. (2022) Polygenic predictions and interactions in hypertension. Cardiac Exercise Research Group (CERG) Exercise in Medicine , Trondheim 2022-12-14 - 2022-12-15
-
PosterØvretveit, Karsten; Ingeström, Emma Maria Lovisa; Spitieris, Michail; Tragante, Vinicius; Wade, Kaitlin Hazel; Thomas, Laurent Francois. (2022) Polygenic predictions and interactions in hypertension. K.G. Jebsen for Genetic Epidemiology Symposium 2022-11-29 - 2022-11-30
2019
-
Academic lectureLøset, Mari; Thomas, Laurent; Brumpton, Ben Michael; Wolford, Brooke N.; Holmen, Oddgeir; Luetge, Almut. (2019) Genome-wide association study of psoriasis suggests a new risk locus on chromosome 10: The HUNT Study. The 34th Nordic Congress of Dermatology & Venereology , Gøteborg 2019-05-08 - 2019-05-10
2018
-
PosterBlankvoort, Stefan; Thomas, Laurent; Witter, Menno; Sætrom, Pål; cotney, Justin; Kentros, Clifford. (2018) The marked diversity of unique cortical enhancers enables neuron-specific tools by Enhancer-Driven Gene Expression (EDGE). Federation of European Neuroscience FENS 2018 , Berlin 2018-07-07 - 2018-07-11
2017
-
Academic lectureThomas, Laurent. (2017) SNPs affecting microRNA-based gene regulation. Jebsen center for genetic epidemiology, NTNU Jebsen center for genetic epidemiology meeting 2017-03-27 - 2017-03-27
-
Academic lectureThomas, Laurent. (2017) SNPs affecting microRNA-based gene regulation. IKM, NTNU Mandagsmøte IKM 2017-04-03 - 2017-04-03
2015
-
Academic lectureThomas, Laurent. (2015) Detection of circular RNAs in Rat. IKM, NTNU Mandagsmøte IKM 2015-11-02 - 2015-11-02
2014
-
Academic lectureThomas, Laurent. (2014) Circular RNAs are depleted of polymorphisms at microRNA binding sites. IKM, NTNU Mandagsmøte IKM 2014-12-01 - 2014-12-01
2013
-
Academic lectureThomas, Laurent. (2013) Single nucleotide polymorphisms in microRNA Binding Sites of circular RNAs. Systems Biology meetings at NTNU 2013-10-11 - 2013-10-11
-
Academic lectureSætrom, Pål; Thomas, Laurent. (2013) Finding SNPs that affect microRNA regulation. 10th International RNAi, MicroRNAs & Single Cell Biology – 2013 Meeting 2013-05-01 - 2013-05-02
2012
-
Academic lectureThomas, Laurent. (2012) Effects of single-nucleotide polymorphisms on microRNA-based gene regulation. Systems Biology meetings at NTNU 2012-10-05 - 2012-10-05
2011
-
Academic lectureThomas, Laurent. (2011) Identifying disease-causative variants in microRNA target sites. Bioinformatics for Young Scientists 2011 , Ullensvang, Hardanger 2011-03-16 - 2011-03-18
-
Academic lectureThomas, Laurent. (2011) Identifying disease-causative variants in microRNA target sites. Pål Sætrom eGenVar møte , Trondheim 2011-03-25 - 2011-03-25
-
Academic lectureThomas, Laurent. (2011) SNPs can create alternative polyadenylation signals and affect gene expression through loss of microRNA-regulation. NTNU bioinformatics & Systems biology groups Systems Biology meetings at NTNU , Trondheim 2011-09-30 - 2011-09-30
-
Academic lectureThomas, Laurent. (2011) Identifying disease-causative variants in microRNA target sites. Institutt for kreftforskning og molekylær medisin, NTNU Mandagsmøte IKM , Trondheim 2011-03-21 - 2011-03-21
2010
-
Academic lectureThomas, Laurent Francois. (2010) Identifying disease-causative variants in microRNA target sites. NTNU bioinformatics & Systems biology groups Systems Biology meetings at NTNU , Trondheim 2010-10-22 - 2010-10-22
-
PosterThomas, Laurent Francois; Saito, Takaya; Sætrom, Pål. (2010) Identifying causative variants in microRNA target sites. Norwegian Radium Hospital / University of Oslo RECOMB Computational Cancer Biology , Oslo 2010-06-24 - 2010-06-25