Magnar Bjørås
About
Prof Magnar Bjørås is a Principle Investigator of the research group of Cellular responses to DNA damage at Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology (NTNU), Trondheim and at Oslo University Hospital/University of Oslo. Bjørås is an expert on genome dynamics with particular emphasis on oxidative stress, DNA base lesion repair and maintenance of epigenetic DNA methylation (epigenome stability).
Our main focus has been on repair of endogenous DNA base lesion repair mechanisms and genome stability. We have made major contributions to characterization of many new DNA repair enzymes from bacteria, yeast and mammalian. Our group has solved the atomic 3D-structure of many DNA-protein complexes revealing several new mechanisms of DNA base damage recognition and catalysis. We have also established research on the role of DNA base lesion repair in neurodegeneration, cognition and behavior, which is a new direction in the DNA repair field revealing novel functions beyond canonical DNA. Furthermore, we have established collaborations with clinicians to study the impact of DNA base lesion repair on diseases such as infections, heart failure, rare neurodegenerative disorders and cancer. We develop new nanoparticle technology for genomics
Project
- Role of oxidative DNA base lesion repair in cancer. Project leader: Magnar Bjørås
- Aberrant Oxidative DNA Modifications and DNA Structures in Genome Regulation. Project leaders: Magnar Bjørås
- Bacterial Toxin-Antitoxin peptides in biological responses to DNA damage. Project leaders: Magnar Bjørås and James Booth
- Pathomechanisms of lysosomal storage disorders in rare neurodegenerative diseases: Project leaders: Magnar Bjørås and Mirta Mittelstedt de Sousa
- Applications of nanoparticle technology in genomics: Project leader: Magnar Bjørås
Publications
2024
-
Otterlei, Marit;
Haugan, Maria Schei;
Bjørås, Magnar;
Müller, Fredrik.
(2024)
Hva bør Norge bidra med for å redusere antibiotikaresistens-krisen?.
Dagens medisin
Reader opinion piece
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Egiazarian, Milena Armenovna;
Abentung, Andreas;
Sakshaug, Teri;
Karabeika, Emily;
Hanumaihgari, Priyanka Reddy;
Grøntvedt, Gøril Rolfseng.
(2024)
The role of impaired oxidative base lesion repair in Alzheimer’s disease.
Alzheimer's & Dementia
Abstract
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Bugaj, Anna Maria;
Kunath, Nicolas;
Saasen, Vidar Langseth;
Fernández Berrocal, Marion Silvana;
Vankova, Ana;
Sætrom, Pål.
(2024)
Dissecting gene expression networks in the developing hippocampus through the lens of NEIL3 depletion.
Progress in Neurobiology
Academic article
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Neurauter, Christine Gran;
Pannone, Marco;
Sousa, Mirta;
Wang, Wei;
Kusnierczyk, Anna;
Luna, Luisa.
(2024)
Enhanced glutathione levels confer resistance to apoptotic and ferroptotic programmed cell death in NEIL DNA glycosylase deficient HAP1 cells.
Free Radical Biology & Medicine
Academic article
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Yang, Mingyi;
Kaarbø, Mari;
Myhre, Vegard;
Reims, Henrik Mikael;
Karlsen, Tom Hemming;
Wang, Junbai.
(2024)
Altered Genome-Wide DNA Methylation in the Duodenum of Common Variable Immunodeficiency Patients.
Journal of Clinical Immunology
Academic article
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Wang, Junbai;
Yang, Mingyi;
Ali, Omer;
Dragland, Jenny Sofie;
Bjørås, Magnar;
Farkas, Lorant.
(2024)
Predicting regulatory mutations and their target genes by new computational integrative analysis: A study of follicular lymphoma.
Computers in Biology and Medicine
Academic article
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Obermann, Tobias;
Sakshaug, Teri Shearer;
Kanagaraj, Vishnu Vignesh;
Abentung, Andreas;
Leal de Sousa, Mirta Mittelstedt;
Hagen, Lars.
(2024)
Genomic 8-oxoguanine modulates gene transcription independent of its repair by DNA glycosylases OGG1 and MUTYH.
Redox Biology
Academic article
-
Bordin, Diana Lilian;
Grooms, Kayla Mae;
Montaldo, Nicola Pietro;
Fordyce Martin, Sarah Louise;
Sætrom, Pål;
Samson, Leona D..
(2024)
Loss of alkyladenine DNA glycosylase alters gene expression in the developing mouse brain and leads to reduced anxiety and improved memory.
DNA Repair
Academic article
-
Ianevski, Aleksandr;
Frøysa, Irene Trøen;
Lysvand, Hilde;
Calitz, Carlemi;
Smura, Teemu;
Nilsen, Hans-Johnny.
(2024)
The combination of pleconaril, rupintrivir, and remdesivir efficiently inhibits enterovirus infections in vitro, delaying the development of drug-resistant virus variants.
Antiviral Research
Academic article
2023
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Starheim, Eirin Johannessen;
Ravlo, Erlend;
Schjølberg, Jørn-Ove;
Solvang, Vanessa;
Wang, Wei;
Scrimgeour, Nathan Robert.
(2023)
NAxtra magnetic nanoparticles for low-cost, efficient isolation of mammalian DNA and RNA.
Scientific Reports
Academic article
-
Ravlo, Erlend;
Ianevski, Aleksandr;
Starheim, Eirin Johannessen;
Wang, Wei;
Ji, Ping;
Lysvand, Hilde.
(2023)
Boosted production of antibodies that neutralized different SARS-CoV-2 variants in a COVID-19 convalescent following messenger RNA vaccination - a case study.
International Journal of Infectious Diseases
Article in business/trade/industry journal
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Lin, Xiaolin;
Wang, Wei;
Yang, Mingyi;
Damseh, Nadirah;
Sousa, Mirta;
Jacob, Fadi.
(2023)
A loss-of-function mutation in human Oxidation Resistance 1 disrupts the spatial–temporal regulation of histone arginine methylation in neurodevelopment.
Genome Biology
Academic article
-
Benjakul, Sopisa;
Anthi, Aina Karen;
Kolderup, Heidi Anette;
Vaysburd, Marina;
Lode, Heidrun Elisabeth;
Mallery, D.
(2023)
A pan-SARS-CoV-2-specific soluble angiotensin-converting enzyme 2-albumin fusion engineered for enhanced plasma half-life and needle-free mucosal delivery.
PNAS Nexus
Academic article
-
Sæbø, Ingvill Pedersen;
Bjørås, Magnar;
Franzyk, Henrik;
Helgesen, Emily;
Booth, James Alexander.
(2023)
Optimization of the Hemolysis Assay for the Assessment of Cytotoxicity.
International Journal of Molecular Sciences
Academic article
-
Schipmann, Stephanie;
Sivakanesan, Sarankan;
Rath, Daniel Stavne;
Brandal, Petter;
Vik-Mo, Einar Osland;
Bjørås, Magnar.
(2023)
Glioblastom hos voksne.
Tidsskrift for Den norske legeforening (Tidsskriftet)
Article in business/trade/industry journal
-
Yang, Mingyi;
Ali, Omer;
Bjørås, Magnar;
Wang, Junbai.
(2023)
Identifying functional regulatory mutation blocks by integrating genome sequencing and transcriptome data.
iScience
Academic article
-
Quiles-Jiménez, Ana M T;
Sousa, Mirta;
Huse, Camilla;
Dyrhol-Riise, Anne Ma;
Holter, Jan Cato;
Christensen, Erik Egeland.
(2023)
Severely ill COVID-19 patients have altered circulating levels of proteins controlling the epitranscriptome.
Journal of Infection
Letter to the editor
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Ravlo, Erlend;
Sousa, Mirta;
Andresen, Lise Lima;
Holberg-Petersen, Mona;
Klundby, Ingvild;
Aas, Per Arne.
(2023)
A fast, low-cost, robust and high-throughput method for viral nucleic acid isolation based on NAxtra magnetic nanoparticles.
Scientific Reports
Academic article
-
Ramos Alonso, Lucia;
Holland, Petter;
Le Gras, Stéphanie;
Zhao, Xu;
Jost, Bernard;
Bjørås, Magnar.
(2023)
Mitotic chromosome condensation resets chromatin to safeguard transcriptional homeostasis during interphase.
Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Academic article
-
Bali, Nesrine;
Brennhaug, Svein Jonsson;
Bjørås, Magnar;
Bandyopadhyay, Sulalit;
Manaf, Adeel.
(2023)
Optimized synthesis of polyacrylic acid-coated magnetic nanoparticles for high-efficiency DNA isolation and size selection.
RSC Advances
Academic article
2022
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Liu, Xin;
Risbakk, Sanne;
Almeida Carvalho, Patricia;
Yang, Mingyi;
Backe, Paul Hoff;
Bjørås, Magnar.
(2022)
Immobilization of FeFe-hydrogenase on black TiO2 nanotubes as biocathodes for the hydrogen evolution reaction.
Electrochemistry communications
Academic article
-
Karlsen, Tom Rune;
Olsen, Maria Belland;
Kong, Xiang Yi;
Yang, Kuan;
Quiles-Jiménez, Ana M T;
Kroustallaki, Pinelopi.
(2022)
NEIL3-deficient bone marrow displays decreased hematopoietic capacity and reduced telomere length.
Biochemistry and Biophysics Reports
Academic article
-
Ali, Omer;
Farooq, Amna;
Yang, Mingyi;
Jin, Victor X.;
Bjørås, Magnar;
Wang, Junbai.
(2022)
abc4pwm: affinity based clustering for position weight matrices in applications of DNA sequence analysis.
BMC Bioinformatics
Academic article
-
Leal de Sousa, Mirta Mittelstedt;
Bjørås, Magnar.
(2022)
Insight into ALKBH8-related intellectual developmental disability based on the first pathogenic missense variant.
Human Genetics
Article in business/trade/industry journal
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Pinto, Sneha M.;
Subbannayya, Yashwanth;
Kim, Hera;
Hagen, Lars;
Górna, Maria W;
Nieminen, Anni I..
(2022)
Multi-OMICs landscape of SARS-CoV-2-induced host responses in human lung epithelial cells.
iScience
Academic article
-
Ianevski, Aleksandr;
Yao, Rouan;
Simonsen, Ronja Meyer;
Myhre, Vegard;
Ravlo, Erlend;
Kaynova, Gerda D..
(2022)
Mono- and combinational drug therapies for global viral pandemic preparedness.
iScience
Academic literature review
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Ravlo, Erlend;
Evensen, Lasse;
Sanson, Gorm;
Hildonen, Siri;
Ianevski, Aleksandr;
Skjervold, Per Olav.
(2022)
Antiviral Immunoglobulins of Chicken Egg Yolk for Potential Prevention of SARS-CoV-2 Infection.
Viruses
Academic article
-
Kaarbø, Mari;
Yang, Mingyi;
Hov, Johannes Espolin Roksund;
Holm, Kristian;
Sousa, Mirta;
Macpherson, Magnhild Eide.
(2022)
Duodenal inflammation in common variable immunodeficiency has altered transcriptional response to viruses.
Journal of Allergy and Clinical Immunology
Academic article
-
Ianevski, Aleksandr;
Simonsen, Ronja Meyer;
Myhre, Vegard;
Tenson, Tanel;
Oksenych, Valentyn;
Bjørås, Magnar.
(2022)
DrugVirus.info 2.0: an integrative data portal for broad-spectrum antivirals (BSA) and BSA-containing drug combinations (BCCs).
Nucleic Acids Research (NAR)
Academic article
-
Kennedy, Lauritz Hagen;
Glesaaen, Emilie Rylund;
Palibrk, Vuk;
Pannone, Marco;
Wang, Wei;
Al-Jabri, Ali.
(2022)
Lactate receptor HCAR1 regulates neurogenesis and microglia activation after neonatal hypoxia-ischemia.
eLIFE
Academic article
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Ianevski, Aleksandr;
Zusinaite, Eva;
Tenson, Tanel;
Oksenych, Valentyn;
Wang, Wei;
Afset, Jan Egil.
(2022)
Novel Synergistic Anti-Enteroviral Drug Combinations.
Viruses
Academic article
-
Ianevski, Aleksandr;
Ahmad, Shahzaib;
Anunnitipat, Kraipit;
Oksenych, Valentyn;
Zusinaite, Eva;
Tenson, Tanel.
(2022)
Seven classes of antiviral agents.
Cellular and Molecular Life Sciences (CMLS)
Academic literature review
-
Olsen, Maria Belland;
Huse, Camilla;
Sousa, Mirta;
Murphy, Sarah Louise Mikalsen;
Sarno, Antonio;
Obermann, Tobias Sebastian.
(2022)
DNA Repair Mechanisms are Activated in Circulating Lymphocytes of Hospitalized Covid-19 Patients.
Journal of Inflammation Research
Academic article
-
Egiazarian, Milena Armenovna;
Strømstad, Silje;
Sakshaug, Teri;
Núñez Nescolarde, Ana Beatriz;
Bethge, Nicole;
Bjørås, Magnar.
(2022)
Age- and sex-dependent effects of DNA glycosylase Neil3 on amyloid pathology, adult neurogenesis, and memory in a mouse model of Alzheimer's disease.
Free Radical Biology & Medicine
Academic article
-
Olsen, Maria Belland;
Sannes, Ann-Christin;
Yang, Kuan;
Nielsen, Morten Birkeland;
Einarsen, Ståle Valvatne;
Christensen, Jan Olav.
(2022)
Mapping of pituitary stress-induced gene regulation connects Nrcam to negative emotions.
iScience
Academic article
-
Quiles-Jiménez, Ana M T;
Dahl, Tuva Børresdatter;
Bjørås, Magnar;
Alseth, Ingrun;
Halvorsen, Bente;
Gregersen, Ida.
(2022)
Epitranscriptome in Ischemic Cardiovascular Disease: Potential Target for Therapies.
Stroke
Academic literature review
2021
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Kunath, Nicolas;
Bugaj, Anna Maria;
Bigonah, Pegah;
Fernandez Berrocal, Marion Silvana;
Bjørås, Magnar;
Ye, Jing.
(2021)
DNA repair enzyme NEIL3 enables a stable neural representation of space by shaping transcription in hippocampal neurons.
iScience
Academic article
-
Maddirevula, Sateesh;
Alameer, Seham;
Ewida, Nour;
Sousa, Mirta;
Bjørås, Magnar;
Vågbø, Cathrine Broberg.
(2021)
Insight into ALKBH8-related intellectual developmental disability based on the first pathogenic missense variant.
Human Genetics
Academic article
-
Ahmadi, Arash;
Till, Katharina;
Backe, Paul Hoff;
Blicher, Pernille;
Diekmann, Robin;
Schüttpelz, Mark.
(2021)
Non-flipping DNA glycosylase AlkD scans DNA without formation of a stable interrogation complex.
Communications Biology
Academic article
-
Quiles-Jiménez, Ana M T;
Gregersen, Ida;
Segers, Filip;
Skarpengland, Tonje;
Kroustallaki, Pinelopi;
Yang, Kuan.
(2021)
DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development.
Atherosclerosis
Academic article
-
Ianevski, Aleksandr;
Yao, Rouan;
Zusinaite, Eva;
Lysvand, Hilde;
Oksenych, Valentyn;
Tenson, Tanel.
(2021)
Active components of commonly prescribed medicines affect influenza a virus–host cell interaction: A pilot study.
Viruses
Academic article
-
Aprigliano, Rossana;
Aksu, Merdane Ezgi;
Bradamante, Stefano;
Mihaljevic, Boris;
Wang, Wei;
Rian, Kristin.
(2021)
Increased p53 signaling impairs neural differentiation in HUWE1-promoted intellectual disabilities.
Cell Reports Medicine
Academic article
-
Lobie, Tekle Airgecho;
Roba, Aklilu Abrham;
Booth, James;
Kristiansen, Knut Ivan;
Aseffa, Abraham;
Skarstad, Kirsten Jane.
(2021)
Antimicrobial resistance: A challenge awaiting the post-COVID-19 era.
International Journal of Infectious Diseases
Academic article
-
Hildrestrand, Gunn Annette;
Rolseth, Veslemøy;
Kunath, Nicolas;
Suganthan, Rajikala;
Jensen, Vidar;
Bugaj, Anna Maria.
(2021)
NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice.
Communications Biology
Academic article
-
Steen, Kristian Wollen;
Hagen, Lars;
Vågbø, Cathrine Broberg;
Rabe, Renana;
Iveland, Tobias Solli;
Aas, Per Arne.
(2021)
ALKBH3 partner ASCC3 mediates P-body formation and selective clearance of MMS-induced 1-methyladenosine and 3-methylcytosine from mRNA.
Journal of Translational Medicine
Academic article
-
Ianevski, Aleksandr;
Yao, Rouan;
Zusinaite, Eva;
Lello, Laura Sandra;
Wang, Sainan;
Jo, Eunji.
(2021)
Synergistic interferon-alpha-based combinations for treatment of sars-cov-2 and other viral infections.
Viruses
Academic article
-
Sousa, Mirta;
Ye, Jing;
Gomez, Luisa Fernanda Luna;
Hildrestrand, Gunn Annette;
Bjørås, Karine;
Scheffler, Katja.
(2021)
Impact of oxidative DNA damage and the role of DNA glycosylases in neurological dysfunction.
International Journal of Molecular Sciences
Academic literature review
-
Meehyun, Ko;
Chang, Soo Young;
Byun, Soo Young;
Ianevski, Aleksandr;
Choi, Inhee;
Pham Hung, Anne-Laure.
(2021)
Screening of FDA-Approved Drugs Using a MERS-CoV Clinical Isolate from South Korea Identifies Potential Therapeutic Options for COVID-19.
Viruses
Academic article
-
Ianevski, Aleksandr;
Yao, Rouan;
Lysvand, Hilde;
Grødeland, Gunnveig;
Legrand, Nicolas;
Oksenych, Valentyn.
(2021)
Nafamostat–interferon-α combination suppresses sars-cov-2 infection in vitro and in vivo by cooperatively targeting host tmprss2.
Viruses
Academic article
-
Ladner, Jason T.;
Henson, Sierra N.;
Boyle, Annalee S.;
Engelbrektson, Anna L.;
Fink, Zane W.;
Rahee, Fatima.
(2021)
Epitope-resolved profiling of the SARS-CoV-2 antibody response identifies cross-reactivity with endemic human coronaviruses.
Cell Reports Medicine
Academic article
-
Quan, Zhilong;
Luo, Chunyang;
Zhu, Bitong;
Zhao, Chungui;
Yang, Mingyi;
Bjørås, Magnar.
(2021)
Synthesis and antimicrobial activities of chitosan/polypropylene carbonate-based nanoparticles.
RSC Advances
Academic article
-
Rolinski, Milosz;
Montaldo, Nicola Pietro;
Aksu, Merdane Ezgi;
Martin, Sarah Fordyce;
Brambilla, Alessandro;
Kunath, Nicolas.
(2021)
Loss of Mediator complex subunit 13 (MED13) promotes resistance to alkylation through cyclin D1 upregulation.
Nucleic Acids Research (NAR)
Academic article
-
Xu, Kaiqi;
Chatzitakis, Athanasios Eleftherios;
Backe, Paul Hoff;
Ruan, Qiushi;
Tang, Junwang;
Rise, Frode.
(2021)
In situ cofactor regeneration enables selective CO2 reduction in a stable and efficient enzymatic photoelectrochemical cell.
Applied Catalysis B: Environmental
Academic article
-
Kong, Xiang Yi;
Huse, Camilla;
Yang, Kuan;
Øgaard, Jonas;
Jimenez, Natalia Berges;
Vik, Erik Sebastian.
(2021)
Endonuclease v regulates atherosclerosis through c-c motif chemokine ligand 2-mediated monocyte infiltration.
Journal of the American Heart Association (JAHA)
Academic article
-
Karlsen, Tom Rune;
Kong, Xiang Yi;
Holm, Sverre;
Quiles-Jiménez, Ana M T;
Dahl, Tuva Børresdatter;
Yang, Kuan.
(2021)
NEIL3-deficiency increases gut permeability and contributes to a pro-atherogenic metabolic phenotype.
Scientific Reports
Academic article
2020
-
Anderssen, Petter Inge;
Ianevski, Aleksandr;
Lysvand, Hilde;
Vitkauskiene, Astra;
Oksenych, Valentyn;
Bjørås, Magnar.
(2020)
Discovery and development of safe-in-man broad-spectrum antiviral agents.
International Journal of Infectious Diseases
Academic literature review
-
Scheffler, Katja;
Jalland, Clara Maria Osnes;
Benestad, Sylvie L.;
Moldal, Torfinn;
Ersdal, Cecilie;
Gunnes, Gjermund.
(2020)
DNA glycosylase Neil2 contributes to genomic responses in the spleen during clinical prion disease.
Free Radical Biology & Medicine
Academic article
-
Xu, Kaiqi;
Chatzitakis, Athanasios Eleftherios;
Risbakk, Sanne;
Yang, Mingyi;
Backe, Paul Hoff;
Grandcolas, Mathieu.
(2020)
High performance and toxicity assessment of Ta3N5 nanotubes for photoelectrochemical water splitting.
Catalysis Today
Academic article
-
Kong, Xiang Yi;
Vik, Erik Sebastian;
Nawaz, Meh Sameen;
Berges, Natalia;
Dahl, Tuva Børresdatter;
Vågbø, Cathrine.
(2020)
Deletion of Endonuclease V suppresses chemically induced hepatocellular carcinoma.
Nucleic Acids Research (NAR)
Academic article
-
Rodriguez-Vargas, José-Manuel;
Martin-Hernandez, Kathline;
Wang, Wei;
Kunath, Nicolas;
Suganthan, Rajikala;
Amé, Jean-Christophe.
(2020)
Parp3 promotes astrocytic differentiation through a tight regulation of Nox4-induced ROS and mTorc2 activation.
Cell Death & Disease
Academic article
-
Yang, Mingyi;
Lin, Xiaolin;
Segers, Filip;
Suganthan, Rajikala;
Hildrestrand, Gunn Annette;
Rinholm, Johanne Egge.
(2020)
OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation.
Cell reports
Academic article
-
Naeini, Alireza Sahaf;
Farooq, Amna;
Bjørås, Magnar;
Wang, Junbai.
(2020)
IGAP-integrative genome analysis pipeline reveals new gene regulatory model associated with nonspecific TF-DNA binding affinity.
Computational and Structural Biotechnology Journal
Academic article
-
Ianevski, Aleksandr;
Yao, Rouan;
Fenstad, Mona H.;
Biza, Svetlana;
Zusinaite, Eva;
Reisberg, Tuuli.
(2020)
Potential Antiviral Options against SARS-CoV-2 Infection. Viruses.
Viruses
Academic article
-
Nedal, Aina;
Ræder, Synnøve Brandt;
Dalhus, Bjørn;
Helgesen, Emily;
Forstrøm, Rune Johansen;
Lindland, Kim.
(2020)
Peptides containing the PCNA interacting motif APIM
bind to the beta-clamp and inhibit bacterial growth and
mutagenesis.
Nucleic Acids Research (NAR)
Academic article
-
Backe, Paul Hoff;
Lærdahl, Jon Kristen;
Kittelsen, Lene Svendsen;
Dalhus, Bjørn;
Mørkrid, Lars;
Bjørås, Magnar.
(2020)
Structural basis for substrate and product recognition in human phosphoglucomutase-1 (PGM1) isoform 2, a member of the α-D-phosphohexomutase superfamily.
Scientific Reports
Academic article
-
Lobie, Tekle Airgecho;
Woldeamanuel, Yimtubezinash;
Asrat, Daniel;
Beyene, Demissew Balcha;
Bjørås, Magnar;
Aseffa, Abraham.
(2020)
Genetic diversity and drug resistance pattern of Mycobacterium tuberculosis strains isolated from pulmonary tuberculosis patients in the Benishangul Gumuz region and its surroundings, Northwest Ethiopia.
PLOS ONE
Academic article
-
Louwe, Maria Cornelia;
Olsen, Maria Belland;
Kaasbøll, Ole Jørgen;
Yang, Kuan;
Fosshaug, Linn Elisabeth Lillerud;
Alfsnes, Katrine.
(2020)
Absence of NLRP3 Inflammasome in Hematopoietic Cells Reduces Adverse Remodeling After Experimental Myocardial Infarction.
JACC: Basic to Translational Science
Academic article
-
Farooq, Amna;
Grønmyr, Sindre;
Omer, Ali Avan;
Rognes, Torbjørn;
Scheffler, Katja;
Bjørås, Magnar.
(2020)
HMST-Seq-Analyzer: A new python tool for differential methylation and hydroxymethylation analysis in various DNA methylation sequencing data.
Computational and Structural Biotechnology Journal
Academic article
-
Quiles Jimenez, Ana Maria Teresa;
Gregersen, Ida;
Sousa, Mirta;
Abbas, Azhar;
Kong, Xiang Yi;
Alseth, Ingrun.
(2020)
N6-methyladenosine in RNA of atherosclerotic plaques: An epitranscriptomic signature of human carotid atherosclerosis.
Biochemical and Biophysical Research Communications - BBRC
Academic article
-
Polec, Anna;
Rowe, Alexander D.;
Blicher, Pernille;
Suganthan, Rajikala;
Bjørås, Magnar;
Bøe, Stig Ove.
(2020)
PML regulates the epidermal differentiation complex and skin morphogenesis during mouse embryogenesis.
Genes
Academic article
-
Ianevski, Aleksandr;
Yao, Rouan;
Biza, Svetlana;
Zusinaite, Eva;
Mannik, Andres;
Kivi, Gaily.
(2020)
Identification and Tracking of Antiviral Drug Combinations.
Viruses
Academic article
-
Bjørås, Magnar.
(2020)
Nobelpris for oppdagelse av hvordan celler tilpasser seg skiftende oksygennivå.
Tidsskrift for Den norske legeforening (Tidsskriftet)
Editorial
-
Booth, James;
Špírek, Mário;
Lobie, Tekle Airgecho;
Skarstad, Kirsten Jane;
Krejci, Lumir;
Bjørås, Magnar.
(2020)
Antibiotic-induced DNA damage results in a controlled loss of pH homeostasis and genome instability.
Scientific Reports
Academic article
-
Ianevski, Aleksandr;
Kulesskiy, Evgeny;
Krpina, Klara;
Lou, Guofeng;
Aman, Yahyah;
Bugai, Andrii.
(2020)
Chemical, Physical and Biological Triggers of Evolutionary Sonserved Bcl-xL-Mediated Apoptosis.
Cancers
Academic article
2019
-
Rognlien, Anne Gro Wesenberg;
Wollen, Embjørg Julianne;
Atneosen-Åsegg, Monica;
Suganthan, Rajikala;
Bjørås, Magnar;
Saugstad, Ola Didrik.
(2019)
Neonatal Ogg1/Mutyh knockout mice have altered inflammatory gene response compared to wildtype mice in the brain and lung after hypoxia-reoxygenation.
Journal of Perinatal Medicine
Academic article
-
Ianevski, Aleksandr;
Anderssen, Petter Inge;
Merits, Andres;
Bjørås, Magnar;
Kainov, Denis.
(2019)
Expanding the activity spectrum of antiviral agents.
Drug Discovery Today
Academic literature review
-
Ahmadi, Arash;
Rosnes, Ida;
Blicher, Pernille;
Diekmann, Robin;
Schuttpelz, Mark;
Glette, Kyrre.
(2019)
Publisher Correction: Breaking the speed limit with multimode fast scanning of DNA by Endonuclease V (Nature Communications, (2018), 9, 1, (5381), 10.1038/s41467-018-07797-4).
Nature Communications
Errata
-
Ystgaard, Martin Bogale;
Scheffler, Katja;
Suganthan, Rajikala;
Bjørås, Magnar;
Ranheim, Trine;
Sagen, Ellen Lund.
(2019)
Neuromodulatory effect of NLRP3 and ASC in neonatal hypoxic ischemic encephalopathy.
Neonatology
Academic article
-
Scheffler, Katja;
Bjørås, Karine Øian;
Bjørås, Magnar.
(2019)
Diverse functions of DNA glycosylases processing oxidative base lesions in brain.
DNA Repair
Academic literature review
-
Berges, Natalia;
Nawaz, Meh Sameen;
Dahl, Tuva Børresdatter;
Hagen, Lars;
Bjørås, Magnar;
Lærdahl, Jon Kristen.
(2019)
Complex alternative splicing of human Endonuclease V mRNA, but evidence for only a single protein isoform.
PLOS ONE
Academic article
-
Montaldo, Nicola Pietro;
Bordin, Diana Lilian;
Brambilla, Alessandro;
Rösinger, Marcel;
Martin, Sarah Fordyce;
Bjørås, Karine Øian.
(2019)
Alkyladenine DNA glycosylase associates with transcription elongation to coordinate DNA repair with gene expression.
Nature Communications
Academic article
-
Ahmadi, Arash;
Till, Katharina;
Hafting, Yngve;
Schuttpelz, Mark;
Bjørås, Magnar;
Glette, Kyrre.
(2019)
Additive manufacturing of laminar flow cells for single-molecule experiments.
Scientific Reports
Academic article
-
Zhang, Zhichao;
Manaf, Adeel;
Li, Yanjiao;
Pérez, Sonia Peña;
Suganthan, Rajikala;
Dahl, John Arne.
(2019)
Histone methylations define neural stem/progenitor cell subtypes in the mouse subventricular zone.
Molecular Neurobiology
Academic article
-
Castaneda Zegarra, Sergio Miguel ;
Huse, Camilla;
Røsand, Øystein;
Sarno, Antonio;
Xing, Mengtan;
Gago-Fuentes, Raquel.
(2019)
Generation of a mouse model lacking the non-homologous end-joining factor Mri/Cyren.
Biomolecules
Academic article
-
Li, Xiang;
Zhao, Qiongyi;
Wei, Wei;
Lin, Quan;
Magnan, Christophe;
Emami, Michael R.
(2019)
The DNA modification N6-methyl-2 '-eoxyadenosine (m6dA) drives activity-induced gene expression and is required for fear extinction.
Nature Neuroscience
Academic article
-
Anderssen, Petter Inge;
Krpina, Klara;
Ianevski, Aleksandr;
Shtaida, Nastassia;
Jo, Eunji;
Yang, Jaewon.
(2019)
Novel antiviral activities of obatoclax, emetine, niclosamide, brequinar, and homoharringtonine.
Viruses
Academic article
-
Bösl, Korbinian;
Ianevski, Aleksandr;
Than, Thoa T.;
Anderssen, Petter Inge;
Kuivanen, Suvi;
Teppor, Mona.
(2019)
Common nodes of virus-host interaction revealed through an integrated network analysis.
Frontiers in Immunology
Academic article
2018
-
Askeland, Georgina;
Rodinova, Marie;
Štufková, Hana;
Dosoudilova, Zaneta;
Baxa, Monika;
Smatlikova, Petra.
(2018)
A transgenic minipig model of Huntington's disease shows early signs of behavioral and molecular pathologies.
Disease Models and Mechanisms
Academic article
-
Zusinaite, Eva;
Ianevski, Aleksandr;
Niukkanen, Diana;
Poranen, Minna M.;
Bjørås, Magnar;
Afset, Jan Egil.
(2018)
A systems approach to study immuno- and neuro-modulatory properties of antiviral agents.
Viruses
Academic literature review
-
Reiten, Malin Rokseth;
Malachin, Giulia;
Kommisrud, Elisabeth;
Østby, Gunn Charlotte;
Waterhouse, Karin Elisabeth;
Krogenæs, Anette Kristine.
(2018)
Stress resilience of spermatozoa and blood mononuclear cells without prion protein.
Frontiers in Molecular Biosciences
Academic article
-
Askeland, Georgina;
Dosoudilova, Zaneta;
Rodinova, Marie;
Klempir, Jiri;
Liskova, Irena;
Kusnierczyk, Anna.
(2018)
Increased nuclear DNA damage precedes mitochondrial dysfunction in peripheral blood mononuclear cells from Huntington's disease patients.
Scientific Reports
Academic article
-
Ahmadi, Arash;
Rosnes, Ida;
Blicher, Pernille;
Diekmann, Robin;
Schüttpelz, Mark;
Glette, Kyrre.
(2018)
Breaking the speed limit with multimode fast scanning of DNA by Endonuclease V.
Nature Communications
Academic article
-
Alexeeva, Marina;
Guragain, Prashanna;
Tesfahun, Almaz Nigatu;
Tomkuvienė, Miglė;
Arshad, Aysha;
Gerasimaitė, Rūta.
(2018)
Excision of the doubly methylated base N4,5-dimethylcytosine from DNA by Escherichia coli Nei and Fpg proteins
.
Philosophical Transactions of the Royal Society of London. Biological Sciences
Academic article
-
Li, Miaomiao;
Zhao, Xu;
Wang, Wei;
Shi, Hailing;
Pan, Qingfei;
Lu, Zhike.
(2018)
Ythdf2-mediated m6A mRNA clearance modulates neural development in mice.
Genome Biology
Academic article
-
Ianevski, Aleksandr;
Zusinaite, Eva;
Kuivanen, Suvi;
Strand, Mårten;
Lysvand, Hilde;
Teppor, Mona.
(2018)
Novel activities of safe-in-human broad-spectrum antiviral agents.
Antiviral Research
Academic article
-
Scheffler, Katja;
Rachek, Lyudmila;
You, Panpan;
Rowe, Alexander D.;
Wang, Wei;
Kuśnierczyk, Anna.
(2018)
8-oxoguanine DNA glycosylase (Ogg1) controls hepatic gluconeogenesis.
DNA Repair
Academic article
-
Gago-Fuentes, Raquel;
Xing, Mengtan;
Sæterstad, Siri;
Sarno, Antonio;
Dewan, Alisa Elinsdatter;
Beck, Carole.
(2018)
Normal development of mice lacking PAXX, the paralogue of XRCC4 and XLF.
FEBS Open Bio
Academic article
-
Bosshard, Matthias;
Aprigliano, Rossana;
Gattiker, Cristina;
Palibrk, Vuk;
Markkanen, Enni;
Backe, Paul Hoff.
(2018)
Publisher Correction: Impaired oxidative stress response characterizes HUWE1-promoted X-linked intellectual disability.
Scientific Reports
Errata
2017
-
Bjørås, Karine;
Sousa, Mirta;
Sharma, Animesh;
Fonseca, Davi de Miranda;
Søgaard, Caroline Danielsen;
Bjørås, Magnar.
(2017)
Monitoring of the spatial and temporal dynamics of BER/SSBR pathway proteins, including MYH, UNG2, MPG, NTH1 and NEIL1-3, during DNA replication.
Nucleic Acids Research (NAR)
Academic article
-
Morland, Cecilie;
Andersson, Krister;
Haugen, Øyvind Pernell;
Hadzic, Alena;
Kleppa, Liv;
Gille, Andreas.
(2017)
Exercise induces cerebral VEGF and angiogenesis via the lactate receptor HCAR1.
Nature Communications
Academic article
-
Rolseth, Veslemøy;
Gomez, Luisa Fernanda Luna;
Olsen, Ann-Karin;
Suganthan, Rajikala;
Scheffler, Katja;
Neurauter, Christine Gran.
(2017)
No cancer predisposition or increased spontaneous mutation frequencies in NEIL DNA glycosylases-deficient mice.
Scientific Reports
Academic article
-
Batmanov, Kirill;
Wang, Wei;
Bjørås, Magnar;
Delabie, Jan;
Wang, Junbai.
(2017)
Integrative whole-genome sequence analysis reveals roles of regulatory mutations in BCL6 and BCL2 in follicular lymphoma.
Scientific Reports
Academic article
-
Xing, Mengtan;
Bjørås, Magnar;
Daniel, Jeremy A.;
Alt, Frederick W.;
Oksenych, Valentyn.
(2017)
Synthetic lethality between murine DNA repair factors XLF and DNA-PKcs is rescued by inactivation of Ku70.
DNA Repair
Academic article
-
Ottesen, Anett Hellebø;
Carlson, Cathrine Rein;
Louch, William Edward;
Dahl, Mai Britt;
Sandbu, Ragnhild Askeland;
Johansen, Rune Forstrøm.
(2017)
Glycosylated Chromogranin A in Heart Failure: Implications for Processing and Cardiomyocyte Calcium Homeostasis.
Circulation: Heart Failure
Academic article
-
Olsen, Maria Belland;
Hildrestrand, Gunn Annette;
Scheffler, Katja;
Vinge, Leif Erik;
Alfsnes, Katrine;
Palibrk, Vuk.
(2017)
NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture.
Cell reports
Academic article
-
Rydning, Siri Lynne;
Backe, Paul Hoff;
Sousa, Mirta;
Iqbal, Zafar;
Øye, Ane-Marte;
Sheng, Ying.
(2017)
Novel UCHL1 mutations reveal new insights into ubiquitin processing.
Human Molecular Genetics
Academic article
-
Pawar, Tina;
Bjørås, Magnar;
Klungland, Arne;
Eide, Lars.
(2017)
Metabolism and DNA repair shape a specific modification pattern in mitochondrial DNA.
Mitochondrion (Amsterdam. Print)
Academic article
-
Bosshard, Matthias;
Aprigliano, Rossana;
Gattiker, Cristina;
Palibrk, Vuk;
Markkanen, Enni;
Backe, Paul Hoff.
(2017)
Impaired oxidative stress response characterizes HUWE1-promoted X-linked intellectual disability.
Scientific Reports
Academic article
-
Rydning, Siri Lynne;
Backe, Paul Hoff;
Sousa, Mirta;
Iqbal, Zafar;
Øye, Ane-Marte;
Sheng, Ying.
(2017)
Corrigendum: Novel UCHL1 mutations reveal new insights into ubiquitin processing.
Human Molecular Genetics
Errata
2016
-
Skarpengland, Tonje;
Holm, Sverre;
Scheffler, Katja;
Gregersen, Ida;
Dahl, Tuva Børresdatter;
Suganthan, Rajikala.
(2016)
Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice.
Scientific Reports
Academic article
-
Petrova, Lucy;
Neurauter, Christine Gran;
Bjørås, Magnar;
Doetsch, Paul W.
(2016)
Efficient and Reliable Production of Vectors for the Study of the Repair, Mutagenesis, and Phenotypic Consequences of Defined DNA Damage Lesions in Mammalian Cells.
PLOS ONE
Academic article
-
Nawaz, Meh Sameen;
Vik, Erik Sebastian;
Berges, Natalia;
Fladeby, Cathrine;
Bjørås, Magnar;
Dalhus, Bjørn.
(2016)
Regulation of Human Endonuclease V Activity and Relocalization to Cytoplasmic Stress Granules.
Journal of Biological Chemistry
Academic article
-
Palibrk, Vuk;
Suganthan, Rajikala;
Scheffler, Katja;
Wang, Wei;
Bjørås, Magnar;
Bøe, Stig Ove.
(2016)
PML regulates neuroprotective innate immunity and neuroblast commitment in a hypoxic–ischemic encephalopathy model.
Cell Death & Disease
Academic article
-
Jalland, Clara Maria Osnes;
Scheffler, Katja;
Benestad, Sylvie Lafond;
Moldal, Torfinn;
Ersdal, Cecilie;
Gunnes, Gjermund.
(2016)
Neil3 induced neurogenesis protects against prion disease during the clinical phase.
Scientific Reports
Academic article
-
Benterud, Torkil;
Ystgaard, Martin Bogale;
Manueldas, Sophia;
Pankratov, Leonid;
Alfaro-Cervello, Clara;
Florholmen, Geir.
(2016)
N-Acetylcysteine Amide Exerts Possible Neuroprotective Effects in Newborn Pigs after Perinatal Asphyxia.
Neonatology
Academic article
-
Dahl, John Arne;
Jung, Inkyung;
Aanes, Håvard;
Greggains, Gareth;
Manaf, Adeel;
Lerdrup, Mads.
(2016)
Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.
Nature
Academic article
-
Kristiansen, Knut Ivan;
Weel-Sneve, Ragnhild;
Booth, James;
Bjørås, Magnar.
(2016)
Mutually exclusive RNA secondary structures regulate translation initiation of DinQ in Escherichia coli.
RNA: A publication of the RNA Society
Academic article
-
Xue, JH;
Xu, GF;
Gu, TP;
Chen, GD;
Han, BB;
Xu, ZM.
(2016)
Uracil-DNA glycosylase UNG promotes tet-mediated DNA demethylation.
Journal of Biological Chemistry
Academic article
-
Nawaz, Meh Sameen;
Vik, Erik Sebastian;
Ronander, Mia Elise;
Solvoll, Anne Marthe;
Blicher, Pernille;
Bjørås, Magnar.
(2016)
Crystal structure and MD simulation of mouse EndoV reveal wedge motif plasticity in this inosine-specific endonuclease.
Scientific Reports
Academic article
-
Schürmann, David;
Scheidegger, Simon P.;
Weber, Alain R.;
Bjørås, Magnar;
Leumann, Christian J.;
Schär, Primo.
(2016)
3CAPS - A structural AP-site analogue as a tool to investigate DNA base excision repair.
Nucleic Acids Research (NAR)
Academic article
-
Skarpengland, Tonje;
Dahl, Tuva Børresdatter;
Skjelland, Mona;
Scheffler, Katja;
Sousa, Mirta;
Gregersen, Ida.
(2016)
Enhanced base excision repair capacity in carotid atherosclerosis may protect nuclear DNA but not mitochondrial DNA.
Free Radical Biology & Medicine
Academic article
2015
-
Bliksøen, Marte;
Baysa, Anton;
Eide, Lars;
Bjørås, Magnar;
Suganthan, Rajikala;
Vaage, Ingvar Jarle.
(2015)
Mitochondrial DNA damage and repair during ischemia-reperfusion injury of the heart.
Journal of Molecular and Cellular Cardiology
Academic article
-
Yang, Mingyi;
Lin, Xiaolin;
Rowe, Alexander D.;
Rognes, Torbjørn;
Eide, Lars;
Bjørås, Magnar.
(2015)
Transcriptome analysis of human OXR1 depleted cells reveals its role in regulating the p53 signaling pathway.
Scientific Reports
Academic article
-
Lundin, Karin E.;
Hamasy, Abdulrahman;
Backe, Paul Hoff;
Moens, Lotte N.;
Falk-Sörqvist, Elin;
Elgstøen, Katja B. Prestø.
(2015)
Susceptibility to infections, without concomitant hyper-IgE, reported in 1976, is caused by hypomorphic mutation in the phosphoglucomutase 3 (PGM3) gene.
Clinical Immunology
Academic article
-
Bjørge, Monica Dahl;
Hildrestrand, Gunn Annette;
Scheffler, Katja;
Suganthan, Rajikala;
Rolseth, Veslemøy;
Kusnierczyk, Anna.
(2015)
Synergistic Actions of Ogg1 and Mutyh DNA Glycosylases Modulate Anxiety-like Behavior in Mice.
Cell reports
Academic article
-
Skarpengland, Tonje;
Laugsand, Lars Erik;
Janszky, Imre;
Gomez, Luisa Fernanda Luna;
Halvorsen, Bente;
Platou, Carl Geoffrey Parrinder.
(2015)
Genetic variants in the DNA repair gene NEIL3 and the risk of myocardial infarction in a nested case-control study. The HUNT Study.
DNA Repair
Academic article
-
Booth, James;
Suganthan, Rajikala;
Gaustad, Peter;
Bjørås, Magnar.
(2015)
Development of DinQ from Escherichia coli as an anti-cell-envelope antibiotic.
International Journal of Antimicrobial Agents
Letter to the editor
-
Seeberg, Trine Margrethe;
Austad, Hanne Opsahl;
Clausen, Ingelin;
Cederkvist, Fritjof Henning;
Bjørås, Magnar;
Johansen, Rune Forstrøm.
(2015)
An in vitro study of Protein Adsorption to Biocompatible Coatings.
IOS Press
Academic chapter/article/Conference paper
-
Ottesen, Anett Hellebø;
Carlson, Cathrine Rein;
Edwards, Andrew;
Landsverk, Ole J. B.;
Johansen, Rune Forstrøm;
Moe, Morten Kaare.
(2015)
Secretoneurin,a novel endogenous CaMKII inhibitor, augments cardiomyocyte Calcium handling and inhibits arrhythmogenic Calcium release.
Biophysical Journal
Abstract
-
Grønland, Mari Therese;
Eijsink, Vincent;
Dalhus, Bjørn;
Bjørås, Magnar;
Carlson, Cathrine Rein.
(2015)
Human CaMKIId mutanter – proteinekspresjon, rensing, krystallisering og analyse av SN-peptid binding.
NMBU,IKBM
Masters thesis
-
Dalhus, Bjørn;
Alseth, Ingrun;
Bjørås, Magnar.
(2015)
Structural basis for incision at deaminated adenines in DNA and RNA by endonuclease V.
Progress in Biophysics and Molecular Biology
Academic literature review
-
Ottesen, Anett Hellebø;
Louch, William Edward;
Carlson, Cathrine Rein;
Landsverk, Ole J. B.;
Kurola, Jouni;
Johansen, Rune Forstrøm.
(2015)
Secretoneurin is a novel prognostic cardiovascular biomarker associated with cardiomyocyte calcium handling.
Journal of the American College of Cardiology
Academic article
2014
-
Ottesen, Anett Hellebø;
Louch, William Edward;
Carlson, Cathrine Rein;
Landsverk, Ole J. B.;
Kurola, Jouni;
Johansen, Rune Forstrøm.
(2014)
Secretoneurin provides independent prognostic information in patients with heart failure and cardiac arrest, and has a direct inhibitory effect on diastolic Ca2+ leak and arrhythmogenic Ca2+ waves via CaMKII inhibition.
Circulation Research
Abstract
-
Yang, Mingyi;
Luna, Linda;
Sørbø, Jan Gunnar;
Alseth, Ingrun;
Johansen, Rune Forstrøm;
Backe, Paul Hoff.
(2014)
Human OXR1 maintains mitochondrial DNA integrity and counteracts hydrogen peroxide-induced oxidative stress by regulating antioxidant pathways involving p21.
Free Radical Biology & Medicine
Academic article
-
Aamann, Maria D.;
Hvitby, Christina;
Popuri, Venkateswarlu;
Muftuoglu, Meltem;
Lemminger, Lasse;
Skeby, Cecilie K..
(2014)
Cockayne Syndrome group B protein stimulates NEIL2 DNA glycosylase activity.
Mechanisms of Ageing and Development
Academic article
-
Stray-Pedersen, Asbjørg;
Backe, Paul Hoff;
Sorte, Hanne Sørmo;
Mørkrid, Lars;
Chokshi, N.Y.;
Erichsen, Hans Christian.
(2014)
PGM3 mutations cause a congenital disorder of glycosylation with severe immunodeficiency and skeletal dysplasia.
American Journal of Human Genetics
Academic article
-
Jalland, Clara;
Benestad, Sylvie Lafond;
Ersdal, Cecilie;
Scheffler, Katja;
Suganthan, Rajikala;
Nakabeppu, Yusaku.
(2014)
Accelerated clinical course of prion disease in mice compromised in repair of oxidative DNA damage.
Free Radical Biology & Medicine
Academic article
-
Strand, Janne Maren;
Scheffler, Katja;
Bjørås, Magnar;
Eide, Lars.
(2014)
The distribution of DNA damage is defined by region-specific susceptibility to DNA damage formation rather than repair differences.
DNA Repair
Academic article
-
Sand, Kine Marita Knudsen;
Dalhus, Bjørn;
Christianson, Gregory J.;
Bern, Malin C.;
Foss, Stian;
Cameron, Jason.
(2014)
Dissection of the neonatal Fc receptor (FcRn)-albumin interface using mutagenesis and anti-FcRn albumin-blocking antibodies.
Journal of Biological Chemistry
Academic article
-
Andersen, Jan Terje;
Dalhus, Bjørn;
Viuff, Dorthe;
Ravn, Birgitte Thue;
Gunnarsen, Kristin Støen;
Plumridge, Andrew.
(2014)
Extending serum half-life of albumin by engineering neonatal Fc receptor (FcRn) binding.
Journal of Biological Chemistry
Academic article
-
Alseth, Ingrun;
Dalhus, Bjørn;
Bjørås, Magnar.
(2014)
Inosine in DNA and RNA.
Current Opinion in Genetics and Development
Academic literature review
-
Maier, Lukas;
Hylse, Ondrej;
Necas, Marek;
Trbusek, Martin;
Ytre-Arne, Mari;
Dalhus, Bjørn.
(2014)
New carbocyclic nucleosides: Synthesis of carbocyclic pseudoisocytidine and its analogs.
Tetrahedron Letters
Academic article
-
Strand, Janne Maren;
Skinnes, Ragnhild;
Scheffler, Katja;
Rootwelt, Terje;
Woldseth, Berit;
Bjørås, Magnar.
(2014)
Genome instability in Maple Syrup Urine Disease correlates with impaired mitochondrial biogenesis.
Metabolism: Clinical and Experimental
Academic article
-
Wang, Wei;
Scheffler, Katja;
Esbensen, Qin Ying;
Strand, Janne Maren;
Stewart, James B.;
Bjørås, Magnar.
(2014)
Addressing RNA integrity to determine the impact of mitochondrial DNA mutations on brain mitochondrial function with age.
PLOS ONE
Academic article
-
Sand, Kine Marita Knudsen;
Dalhus, Bjørn;
Christianson, Gregory J.;
Bern, Malin C.;
Foss, Stian;
Cameron, Jason.
(2014)
Dissection of the neonatal Fc receptor (FcRn)-albumin interface using mutagenesis and anti-FcRn albumin-blocking antibodies.
Journal of Biological Chemistry
Academic article
2013
-
Zimmermann, Christine;
Santos, Aline;
Gable, Kenneth;
Epstein, Sharon;
Gururaj, Charulatha;
Chymkowitch, Pierre.
(2013)
TORC1 Inhibits GSK3-Mediated Elo2 Phosphorylation to Regulate Very Long Chain Fatty Acid Synthesis and Autophagy.
Cell reports
Academic article
-
Bousquet, Paula;
Abshiru, Nebiyu;
Johansen, Rune Forstrøm;
Bjørås, Magnar;
Sandvik, Joe Alexander;
Pettersen, Erik O.
(2013)
A structural and functional study of anti-ganglioside antibodies.
International Journal of Molecular Medicine
Abstract
-
Booth, James A.;
Thomassen, Gard O Sundby;
Rowe, Alexander D.;
Weel-Sneve, Ragnhild;
Lagesen, Karin;
Kristiansen, Knut Ivan.
(2013)
Tiling array study of MNNG treated Escherichia coli reveals a widespread transcriptional response.
Scientific Reports
Academic article
-
Ottesen, Anett Hellebø;
Louch, William Edward;
Carlson, Cathrine Rein;
Landsverk, Ole J. B.;
Johansen, Rune forstrom;
Moe, Morten.
(2013)
Secretoneurin is a novel endogenous CaMKII inhibitor that regulates cardiomyocyte calcium handling and is closely associated with mortality in patients with acute heart failure.
Circulation
Abstract
-
Backe, Paul Hoff;
Simm, Roger;
Lærdahl, Jon Kristen;
Dalhus, Bjørn;
Fagerlund, Annette;
Økstad, Ole Andreas Løchen.
(2013)
A new family of proteins related to the HEAT-like repeat DNA glycosylases with affinity for branched DNA structures.
Journal of Structural Biology
Academic article
-
Simonelli, V;
Camerini, S;
Mazzei, F;
Van Loon, B;
Allione, A;
D'Errico, M.
(2013)
Genotype-phenotype analysis of S326C OGG1 polymorphism: a risk factor for oxidative pathologies.
Free Radical Biology & Medicine
Academic article
-
Rognlien, Anne Gro Wesenberg;
Wollen, Embjørg Julianne;
Bjørås, Magnar;
Saugstad, Ola Didrik.
(2013)
DNA Glycosylases Protect the Newborn Mouse Lung from Apoptosis, Cell Cycle Arrest and Inflammation.
Neonatology
Abstract
-
Rosnes, Ida;
Rowe, Alexander D.;
Vik, Erik Sebastian;
Johansen, Rune Forstrøm;
Alseth, Ingrun;
Bjørås, Magnar.
(2013)
Structural Basis of DNA Loop Recognition by Endonuclease V.
Structure
Academic article
-
Weel-Sneve, Ragnhild;
Kristiansen, Knut Ivan;
Odsbu, Ingvild;
Dalhus, Bjørn;
Booth, James;
Rognes, Torbjørn.
(2013)
Single Transmembrane Peptide DinQ Modulates Membrane-Dependent Activities.
PLoS Genetics
Academic article
-
Dalhus, Bjørn;
Nilsen, Line;
Korvald, Hanne;
Huffman, Joy;
Johansen, Rune Forstrøm;
McMurray, Cynthia T..
(2013)
Sculpting of DNA at Abasic Sites by DNA Glycosylase Homolog Mag2.
Structure
Academic article
-
Bliksrud, Yngve Thomas;
Ellingsen, Amund;
Bjørås, Magnar.
(2013)
Fumarylacetoacetate inhibits the initial step of the base excision repair pathway: implication for the pathogenesis of tyrosinemia type I.
The Journal of Inherited Metabolic Disease (JIMD)
Academic article
-
Backe, Paul Hoff;
Ytre-Arne, Mari;
Røhr, Åsmund Kjendseth;
Brodtkorb, Else;
Fowler, Brian;
Rootwelt, Helge.
(2013)
Novel Deletion Mutation Identified in a Patient with Late-Onset Combined Methylmalonic Acidemia and Homocystinuria, cblC Type.
JIMD Reports
Academic article
-
Rolseth, Veslemøy;
Krokeide, Silje Z;
Kunke, David;
Neurauter, Christine Gran;
Suganthan, Rajikala;
Sejersted, Yngve.
(2013)
Loss of Neil3, the major DNA glycosylase activity for removal of hydantoins in single stranded DNA, reduces cellular proliferation and sensitizes cells to genotoxic stress.
BBA - Molecular Cell Research
Academic article
-
Krokan, Hans Einar;
Bjørås, Magnar.
(2013)
Base Excision Repair.
Cold Spring Harbor Perspectives in Biology
Academic article
-
Simonelli, Valeria;
Camerini, Serena;
Mazzei, Filomena;
Loon, Barbara Van;
Allione, Alessandra;
Mariarosaria, D'Errico.
(2013)
Genotype–phenotype analysis of S326C OGG1 polymorphism: a risk factor for oxidative pathologies.
Free Radical Biology & Medicine
Academic article
-
Krokeide, Silje Zandstra;
Lærdahl, Jon Kristen;
Salah, Medya;
Luna, Luisa;
Cederkvist, Fritjof Henning;
Fleming, Aaron M..
(2013)
Human NEIL3 is mainly a monofunctional DNA glycosylase removing spiroimindiohydantoin and guanidinohydantoin.
DNA Repair
Academic article
-
Zhang, Xiao;
Shi, Ming;
Bjørås, Magnar;
Wang, Wei;
Zhang, Guangyun;
Han, Junliang.
(2013)
Ginsenoside Rd promotes glutamate clearance by up-regulating glial glutamate transporter GLT-1 via PI3K/AKT and ERK1/2 pathways.
Frontiers in Pharmacology
Academic article
-
Jobert, Laure;
Skjeldam, Hanne Kim;
Dalhus, Bjørn;
Galashevskaya, Anastasia;
Vågbø, Cathrine Broberg;
Bjørås, Magnar.
(2013)
The human base excision repair enzyme SMUG1 directly interacts with DKC1 and contributes to RNA quality control.
Molecular Cell
Academic article
-
Vik, Erik Sebastian;
Nawaz, Meh Sameen;
Andersen, Pernille Strøm;
Fladeby, Cathrine;
Bjørås, Magnar;
Dalhus, Bjørn.
(2013)
Endonuclease V cleaves at inosines in RNA.
Nature Communications
Academic article
2012
-
Andersen, Jan Terje;
Dalhus, Bjørn;
Cameron, Jason;
Daba, Muluneh Bekele;
Plumridge, Andrew;
Evans, Leslie.
(2012)
Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor.
Nature Communications
Academic article
-
Hudecova, Alexandra;
Kusznierewicz, Barbara;
Rundén-Pran, Elise;
Magdolenova, Zuzana;
Hasplova, Katarina;
Rinna, Alessandra.
(2012)
Silver nanoparticles induce premutagenic DNA oxidation that can be prevented by phytochemicals from Gentiana asclepiadea.
Mutagenesis
Academic article
-
Nilsen, Line;
Forstrøm, Rune Johansen;
Bjørås, Magnar;
Alseth, Ingrun.
(2012)
AP endonuclease independent repair of abasic sites in Schizosaccharomyces pombe.
Nucleic Acids Research (NAR)
Academic article
-
Hasplova, Katarina;
Hudecova, Alexandra;
Magdolenova, Zuzana;
Bjørås, Magnar;
Galova, Eliska;
Miadokova, Eva.
(2012)
DNA alkylation lesions and their repair in human cells: Modification of the comet assay with 3-methyladenine DNA glycosylase (AlkD).
Toxicology Letters
Academic article
-
Halsne, Ruth;
Esbensen, Qin Ying;
Wang, Wei;
Scheffler, Katja;
Suganthan, Rajikala;
Bjørås, Magnar.
(2012)
Lack of the DNA glycosylases MYH and OGG1 in the cancer prone double mutant mouse does not increase mitochondrial DNA mutagenesis.
DNA Repair
Academic article
-
Vaaje-Kolstad, Gustav;
Bøhle, Liv Anette;
Gåseidnes, Sigrid;
Dalhus, Bjørn;
Bjørås, Magnar;
Mathiesen, Geir.
(2012)
Characterization of the Chitinolytic Machinery of Enterococcus faecalis V583 and High-Resolution Structure of Its Oxidative CBM33 Enzyme.
Journal of Molecular Biology (JMB)
Academic article
-
Søberg, Kristoffer;
Larsen, Anja C V;
Diskar, Mandy;
Backe, Paul Hoff;
Bjørås, Magnar;
Jahnsen, Tore.
(2012)
Identification and Characterization of Novel Mutations in the Human Gene Encoding the Catalytic Subunit Calpha of Protein Kinase A (PKA).
PLOS ONE
Academic article
-
Hereng, Tuva Holt;
Backe, Paul Hoff;
Kahmann, Jan;
Scheich, Christoph;
Bjørås, Magnar;
Skålhegg, Bjørn Steen.
(2012)
Structure and function of the human sperm-specific isoform of protein kinase A (PKA) catalytic subunit C alpha 2.
Journal of Structural Biology
Academic article
-
Fladeby, Cathrine;
Vik, Erik Sebastian;
Lærdahl, Jon Kristen;
Neurauter, Christine Gran;
Heggelund, Julie Elisabeth;
Thorgaard, Eirik.
(2012)
The Human Homolog of Escherichia coli Endonuclease V Is a Nucleolar Protein with Affinity for Branched DNA Structures.
PLOS ONE
Academic article
-
Rognlien, Anne Gro Wesenberg;
Wollen, Embjørg Julianne;
Atneosen-Åsegg, Monica;
Bjørås, Magnar;
Saugstad, Ola Didrik.
(2012)
290 Genes Important in Inflammation, Apoptosis, Transcription Regulation and Angiogenesis are Induced in the Newborn Mouse Brain after Hypoxia-Reoxygenation (HR).
Archives of Disease in Childhood
Abstract
-
Wollen, Embjørg Julianne;
Rognlien, Anne Gro Wesenberg;
Atneosen-Åsegg, Monica;
Bjørås, Magnar;
Saugstad, Ola Didrik.
(2012)
1779 Cell Death Genes are Induced Immediately after Hypoxia-Reoxygenation (HR) in the Newborn Mouse Lung.
Archives of Disease in Childhood
Abstract
-
Zimmermann, Christine;
Chymkowitch, Pierre;
Eldholm, Vegard;
Putnam, Christopher D.;
Lindvall, Jessica M.;
Omerzu, Manja.
(2012)
A chemical-genetic screen to unravel the genetic network of CDC28/CDK1 links ubiquitin and Rad6-Bre1 to cell cycle progression.
The FASEB Journal
Abstract
-
Vik, Erik Sebastian;
Alseth, Ingrun;
Forsbring, Monika;
Helle, Ina Høydal;
Morland, Ingrid;
Luna, Luisa.
(2012)
Biochemical mapping of human NEIL1 DNA glycosylase and AP lyase activities.
DNA Repair
Academic article
-
Payne, Christina M.;
Baban, Jamil;
Horn, Svein Jarle;
Backe, Paul Hoff;
Arvai, Andrew S.;
Dalhus, Bjørn.
(2012)
Hallmarks of processivity in glycoside hydrolases from crystallographic and computational studies of the Serratia marcescens chitinases.
Journal of Biological Chemistry
Academic article
-
Ranneberg-Nilsen, Toril;
Rollag, Halvor;
Slettebakk, Ragnhild;
Backe, Paul Hoff;
Olsen, Øyvind;
Luna, Luisa.
(2012)
The Chromatin Remodeling Factor SMARCB1 Forms a Complex with Human Cytomegalovirus Proteins UL114 and UL44.
PLOS ONE
Academic article
-
Saugstad, Ola Didrik;
Sejersted, Yngve;
Solberg, Rønnaug;
Wollen, Embjørg Julianne;
Bjørås, Magnar.
(2012)
Oxygenation of the Newborn: A Molecular Approach.
Neonatology
Academic article
-
Møllersen, Linda;
Rowe, Alexander D.;
Illuzzi, Jennifer L.;
Hildrestrand, Gunn Annette;
Gerhold, Katharina J.;
Tveterås, Linda Augustin.
(2012)
Neil1 is a genetic modifier of somatic and germline CAG trinucleotide repeat instability in R6/1 mice.
Human Molecular Genetics
Academic article
-
Neurauter, Christine Gran;
Luna, Luisa;
Bjørås, Magnar.
(2012)
Release from quiescence stimulates the expression of human NEIL3 under the control of the Ras dependent ERK-MAP kinase pathway.
DNA Repair
Academic article
-
Korvald, Hanne;
Falnes, Pål;
Lærdahl, Jon Kristen;
Bjørås, Magnar;
Alseth, Ingrun.
(2012)
The Schizosaccharomyces pombe AlkB homolog Abh1 exhibits AP lyase activity but no demethylase activity.
DNA Repair
Academic article
-
Regnell, Christine E;
Hildrestrand, Gunn Annette;
Sejersted, Yngve;
Medin, Tirill;
Moldestad, Olve;
Rolseth, Veslemøy.
(2012)
Hippocampal Adult Neurogenesis Is Maintained by Neil3-Dependent Repair of Oxidative DNA Lesions in Neural Progenitor Cells.
Cell reports
Academic article
-
Lång, Emma Helena;
Grudic, Amra;
Pankiv, Serhiy;
Bruserud, Øystein;
Simonsen, Anne;
Bjerkvig, Rolf.
(2012)
The arsenic-based cure of acute promyelocytic leukemia promotes cytoplasmic sequestration of PML and PML/RARA through inhibition of PML body recycling.
Blood
Academic article
-
Chymkowitch, Pierre;
Eldholm, Vegard;
Lorenz, Susanne;
Zimmermann, Christine;
Lindvall, Jessica M.;
Bjørås, Magnar.
(2012)
Cdc28 kinase activity regulates the basal transcription machinery at a subset of genes.
Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Academic article
2011
-
Dalhus, Bjørn;
Forsbring, Monika;
Helle, Ina Høydal;
Vik, Erik Sebastian;
Johansen, Rune Forstrøm;
Backe, Paul Hoff.
(2011)
Separation-of-Function Mutants Unravel the Dual-Reaction Mode of Human 8-Oxoguanine DNA Glycosylase.
Structure
Academic article
-
Arczewska, Katarzyna;
Baumeier, Christian;
Kassahun, Henok;
Sengupta, Tanima;
Bjørås, Magnar;
Kuśmierek, Jarosław T..
(2011)
Caenorhabditis elegans NDX-4 is a MutT-type enzyme that contributes to genomic stability.
DNA Repair
Academic article
-
Lauritzen, Knut Husø;
Dalhus, Bjørn;
Storm, Johan Frederik;
Bjørås, Magnar;
Klungland, Arne.
(2011)
Modeling the impact of mitochondrial DNA damage in forebrain neurons and beyond.
Mechanisms of Ageing and Development
Academic article
-
Wang, Wei;
Esbensen, Ying;
Kunke, David;
Suganthan, Rajikala;
Rachek, Lyudmila;
Bjørås, Magnar.
(2011)
Mitochondrial DNA Damage Level Determines Neural Stem Cell Differentiation Fate.
Journal of Neuroscience
Academic article
-
Sejersted, Yngve;
Hildrestrand, Gunn Annette;
Kunke, David;
Rolseth, Veslemøy;
Krokeide, Silje Z.;
Neurauter, Christine Gran.
(2011)
Endonuclease VIII-like 3 (Neil3) DNA glycosylase promotes neurogenesis induced by hypoxia-ischemia.
Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Academic article
-
Zimmermann, Christine;
Chymkowitch, Pierre;
Eldholm, Vegard;
Putnam, Christopher D.;
Lindvall, Jessica Margareta;
Omerzu, Manja.
(2011)
A chemical-genetic screen to unravel the genetic network of CDC28/CDK1 links ubiquitin and Rad6-Bre1 to cell cycle progression.
Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Academic article
-
Korvald, Hanne;
Moe, Anne Margrethe Mølstad;
Cederkvist, Fritjof Henning;
Thiede, Bernd;
Lærdahl, Jon Kristen;
Bjørås, Magnar.
(2011)
Schizosaccharomyces pombe Ofd2 Is a Nuclear 2-Oxoglutarate and Iron Dependent Dioxygenase Interacting with Histones.
PLOS ONE
Academic article
-
Johnsen, Line;
Flåtten, Ingvild;
Morigen, Morigen;
Dalhus, Bjørn;
Bjørås, Magnar;
Waldminghaus, Torsten.
(2011)
The G157C mutation in the Escherichia coli sliding clamp specifically affects initiation of replication.
Molecular Microbiology
Academic article
-
Lærdahl, Jon Kristen;
Korvald, Hanne;
Nilsen, Line;
Dahl-Michelsen, Kristin;
Rognes, Torbjørn;
Bjørås, Magnar.
(2011)
Schizosaccharomyces pombe encodes a mutated AP endonuclease 1.
DNA Repair
Academic article
-
Yang, Mingyi;
Aamodt, Randi;
Dalhus, Bjørn;
Balasingham, Seetha ;
Helle, Ina Høydal;
Andersen, Pernille Strøm.
(2011)
The ada operon of Mycobacterium tuberculosis encodes two DNA methyltransferases for inducible repair of DNA alkylation damage.
DNA Repair
Academic article
2010
-
Arczewska, Katarzyna;
Baumeier, Christian;
Kassahun, Henok;
Sengupta, Tanima;
Bjørås, Magnar;
Kuśmierek, Jarosław T..
(2010)
Caenorhabditis elegans NDX-4 is a MutT-type enzyme that contributes to genomic stability.
DNA Repair
Academic article
-
Dalen, Marit Lunde;
Alme, Tomas Nordheim;
Bjørås, Magnar;
Munkeby, Berit Holthe;
Rootwelt, Terje;
Saugstad, Ola Didrik.
(2010)
Reduced expression Of DNA glycosylases in post-hypoxic newborn pigs undergoing therapeutic hypothermia.
Brain Research
Academic article
-
Sneve, Ragnhild;
Bjørås, Magnar.
(2010)
Microbial RNomics and the role of small transmembrane peptides in genotoxic stress control.
Unipub forlag
Series of dissertations submitted to the Faculty of Medicine, University of Oslo (1051)
Doctoral dissertation
-
Thomassen, Gard O Sundby;
Sneve, Ragnhild;
Rowe, Alexander D.;
Booth, James;
Lindvall, Jessica M.;
Lagesen, Karin.
(2010)
Tiling Array Analysis of UV Treated Escherichia coli Predicts Novel Differentially Expressed Small Peptides.
PLOS ONE
Academic article
-
Isakson, Pauline;
Bjørås, Magnar;
Bøe, Stig Ove;
Simonsen, Anne.
(2010)
Autophagy contributes to therapy-induced degradation of the PML/RARA oncoprotein.
Blood
Academic article
-
Bøyum, Arne;
Skrede, Knut Kristian;
Myhre, Oddvar;
Tennfjord, Vivi-Ann;
Neurauter, Christine Gran;
Tolleshaug, Helge.
(2010)
Calprotectin (S100A8/S100A9) and myeloperoxidase: Co-regulators of formation of reactive oxygen species.
Toxins
Academic article
-
Solberg, R.;
Andresen, Jannicke Hanne;
Borge, Grethe iren andersen;
Ellingsen, A.;
Bjørås, Magnar;
Saugstad, Ola Didrik.
(2010)
Resuscitation with 100% Oxygen Gives Increased Oxidative Stress in Lung Tissue and Influences the Capacity to Repair Base Lesions on DNA.
Neonatology
Abstract
-
Wang, Wei;
Osenbroch, Pia Madeleine Øistad;
Skinnes, Ragnhild;
Esbensen, Qin Ying;
Bjørås, Magnar;
Eide, Lars.
(2010)
Mitochondrial DNA Integrity Is Essential for Mitochondrial Maturation During Differentiation of Neural Stem Cells.
Stem Cells
Academic article
-
Brodtkorb, Else;
Strand, Janne Maren;
Backe, Paul Hoff;
Lund, Anne Marie;
Bjørås, Magnar;
Rootwelt, Terje.
(2010)
Four novel mutations identified in Norwegian patients result in intermittent maple syrup urine disease when combined with the R301C mutation.
Molecular Genetics and Metabolism
Academic article
-
Bliksrud, Yngve Thomas;
Ellingsen, Anne;
Bjørås, Magnar.
(2010)
TYROSINEMIA TYPE 1-EFFECT OF METABOLITES ON FIVE DIFFERENT DNA- REPAIR ENZYMES.
The Journal of Inherited Metabolic Disease (JIMD)
Abstract
2009
-
Dalhus, Bjørn;
Lærdahl, Jon Kristen;
Backe, Paul Hoff;
Bjørås, Magnar.
(2009)
DNA base repair - recognition and initiation of catalysis.
FEMS Microbiology Reviews
Academic literature review
-
Hildrestrand, Gunn Annette;
Neurauter, Christine Gran;
Diep, Dzung Bao;
Castellanos, Cesilie Granum;
Krauss, Stefan;
Bjørås, Magnar.
(2009)
Expression patterns of Neil3 during embryonic brain development and neoplasia.
BMC Neuroscience
Academic article
-
Bliksrud, Yngve Thomas;
Ellingsen, Anne;
Bjørås, Magnar.
(2009)
TYROSINEMIA TYPE 1-THE DNA-REPAIR ENZYMES NEIL1 AND NEIL2 ARE INHIBITED BY FUMARYLACETOACETATE.
Molecular Genetics and Metabolism
Abstract
-
Straume, Daniel;
Johansen, Rune Forstrøm;
Bjørås, Magnar;
Nes, Ingolf F.;
Diep, Dzung Bao.
(2009)
DNA binding kinetics of two response regulators, PlnC and PlnD, from the bacteriocin regulon of Lactobacillus plantarum C11.
BMC Biochemistry
Academic article
-
Dalhus, Bjørn;
Arvai, AS;
Rosnes, Ida;
Olsen, Øyvind Edon;
Backe, Paul Hoff;
Alseth, Ingrun.
(2009)
Structures of endonuclease V with DNA reveal initiation of deaminated adenine repair.
Nature Structural & Molecular Biology
Academic article
-
Yndestad, Arne;
Neurauter, Christine Gran;
Øie, Erik;
Johansen, Rune Forstrøm;
Vinge, Leif Erik;
Eide, Lars.
(2009)
Up-regulation of myocardial DNA base excision repair activities in experimental heart failure.
Mutation research
Academic article
-
Forsbring, Monika;
Vik, Erik Sebastian;
Dalhus, Bjørn;
Karlsen, Tom Hemming;
Bergquist, A.;
Schrumpf, Erik.
(2009)
Catalytically impaired hMYH and NEIL1 mutant proteins identified in patients with primary sclerosing cholangitis and cholangiocarcinoma.
Carcinogenesis
Academic article
-
Straume, Daniel;
Johansen, Rune F;
Bjørås, Magnar;
Nes, Ingolf F.;
Diep, Dzung Bao.
(2009)
DNA binding kinetics of two response regulators, PlnC and PlnD, from the bacteriocin regulon of Lactobacillus plantarum C11.
BMC Biochemistry
Academic article
-
krokeide, Silje Z.;
Bolstad, Nils;
Lærdahl, Jon Kristen;
Bjørås, Magnar;
Luna, Luisa.
(2009)
Expression and purification of NEIL3, a human DNA glycosylase homolog.
Protein Expression and Purification
Academic article
-
Sejersted, Yngve;
Aasland, Anne Leikny;
Bjørås, Magnar;
Eide, Lars;
Saugstad, Ola Didrik.
(2009)
Accumulation of 8-Oxoguanine in Liver DNA During Hyperoxic Resuscitation of Newborn Mice.
Pediatric Research
Academic article
-
Hildrestrand, Gunn Annette;
Duggal, Shivali;
Bjørås, Magnar;
Luna, Luisa;
Brinchmann, Jan E..
(2009)
Modulation of DNA glycosylase activities in mesenchymal stem cells.
Experimental Cell Research
Academic article
2008
-
de Jesus, BMB;
Bjørås, Magnar;
Coin, F;
Egly, JM.
(2008)
Dissection of the Molecular Defects Caused by Pathogenic Mutations in the DNA Repair Factor XPC.
Molecular and Cellular Biology
Academic article
-
Rolseth, Veslemøy;
Runden, Elise;
Luna, Gomez Luisa;
McMurray, C;
Bjørås, Magnar;
Ottersen, Ole Petter.
(2008)
Widespread distribution of DNA glycosylases removing oxidative DNA lesions in human and rodent brains.
DNA Repair
Academic article
-
Ranneberg-Nilsen, T;
Dale, HA;
Luna, L;
Slettebakk, R;
Sundheim, Ottar;
Rollag, H.
(2008)
Characterization of human cytomegalovirus uracil DNA glycosylase (UL114) and its interaction with polymerase processivity factor (UL44).
Journal of Molecular Biology (JMB)
Academic article
-
Rolseth, Veslemøy;
Runden, Elise;
Neurauter, Christine Gran;
Yndestad, Arne;
Luna, Gomez Luisa;
Aukrust, Pål.
(2008)
Base excision repair activities in organotypic hippocampal slice cultures exposed to oxygen and glucose deprivation.
DNA Repair
Academic article
-
Allunans, Juris;
Kristiansen, Knut Ivan;
Assalkhou, Reza;
Bjørås, Magnar.
(2008)
Bacteriocins (meningocins) in Norwegian isolates of Neisseria meningitidis: possible role in the course of a meningococcal epidemic.
APMIS - Journal of Pathologiy, Microbiology and Immunology
Academic article
2007
-
Assalkhou, Reza;
Balasingham, Seetha;
Collins, RF;
Frye, Stephan Alfons;
Davidsen, Tonje;
Benam, AV.
(2007)
The outer membrane secretin PilQ from Neisseria meningitidis binds DNA.
Microbiology (Reading)
Academic article
-
Kovtun, IV;
Liu, Y;
Bjørås, Magnar;
Klungland, Arne;
Wilson, SH;
McMurray, CT.
(2007)
OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells.
Nature
Academic article
-
Rolseth, Veslemøy;
Bjørås, Magnar.
(2007)
DNA glycosylases initiating repair of oxidative DNA lesions in mammalian cells.
Unipub forlag
Dissertation for the degree of Dr.Med. (541)
Doctoral dissertation
-
Dalhus, Bjørn;
Helle, Ina Høydal;
Backe, Paul Hoff;
Alseth, Ingrun;
Rognes, Torbjørn;
Bjørås, Magnar.
(2007)
Structural insight into repair of alkylated DNA by a new superfamily of DNA glycosylases comprising HEAT-like repeats.
Nucleic Acids Research (NAR)
Academic article
-
Davidsen, Tonje;
Tuven, Hanne Kim;
Bjørås, Magnar;
Rødland, Einar Andreas;
Tønjum, Tone.
(2007)
Genetic interactions of DNA repair pathways in the pathogen Neisseria meningitidis.
Journal of Bacteriology
Academic article
2006
-
Walberg, Mette;
Mørk, Cato;
Sandven, Per;
Jorde, Anne Tomine;
Bjørås, Magnar;
Gaustad, Peter.
(2006)
18S rDNA polymerase chain reaction and sequencing in onychomycosis diagnostics.
Acta Dermato-Venereologica
Academic article
-
Ranneberg-Nilsen, Toril;
Bjørås, Magnar;
Luna, Gomez Luisa;
Slettebakk, Ragnhild;
Dale, Hege Avsnes;
Seeberg, Erling Christen.
(2006)
Human cytomegalovirus infection modulates DNA base excision repair in fibroblast cells.
Virology
Academic article
-
D'Errico, M;
Parlanti, E;
Teson, M;
de Jesus, BMB;
Degan, P;
Calcagnile, A.
(2006)
New functions of XPC in the protection of human skin cells from oxidative damage.
EMBO Journal
Academic article
-
Alseth, Ingrun;
Rognes, Torbjørn;
Lindbäck, Toril;
Solberg, Inger;
Robertsen, Kristin;
Kristiansen, Knut Ivan.
(2006)
A new protein superfamily includes two novel 3-methyladenine DNA glycosylases from Bacillus cereus, AlkC and AlkD.
Molecular Microbiology
Academic article
2005
-
Aukrust, Pål;
Luna, Luisa;
Ueland, Thor;
Johansen, Rune Forstrøm;
Muller, Fredrik;
Frøland, Stig Sophus.
(2005)
Impaired base excision repair and accumulation of oxidative base lesions in CD4+ T cells of HIV-infected patients.
Blood
Academic article
-
Luna, Gomez Luisa;
Luna, L;
Rolseth, V;
Hildrestrand, GA;
Otterlei, Marit;
Dantzer, F.
(2005)
Dynamic relocalization of hOGG1 during the cell cycle is disrupted in cells harbouring the hOGG1-Cys(326) polymorphic variant.
Nucleic Acids Research (NAR)
Academic article
-
Davidsen, Tonje;
Bjørås, Magnar;
Seeberg, Erling Christen;
Tønjum, Tone.
(2005)
Antimutator role of DNA glycosylase MutY in pathogenic Neisseria species.
Journal of Bacteriology
Academic article
-
Morland, Ingrid;
Luna, Gomez Luisa;
Gustad, Ellen Cecilie;
Seeberg, Erling Christen;
Bjørås, Magnar.
(2005)
Product inhibition and magnesium modulate the dual reaction mode of hOgg1.
DNA Repair
Academic article
2004
-
Falnes, Pål;
Bjoras, M;
Bjørås, Magnar;
Aas, PA;
Sundheim, Ottar;
Seeberg, E.
(2004)
Substrate specificities of bacterial and human AlkB proteins.
Nucleic Acids Research (NAR)
Academic article
-
Alseth, Ingrun;
Korvald, Hanne;
Osman, F.;
Seeberg, Erling Christen;
Bjørås, Magnar.
(2004)
A general role of the DNA glycosylase Nth1 in the abasic sites cleavage step of base excision repair in Schizosaccharomyces pombe.
Nucleic Acids Research (NAR)
Academic article
-
Aamodt, Randi;
Falnes, Pål;
Johansen, RF;
Seeberg, Erling Christen;
Bjørås, Magnar.
(2004)
The Bacillus subtilis counterpart of the mammalian 3-methyladenine DNA glycosylase has hypoxanthine and 1,N-6-ethenoadenine as preferred substrates.
Journal of Biological Chemistry
Academic article
2003
-
Aas, Per Arne;
Otterlei, Marit;
Falnes, P.Ø;
Vågbø, Cathrine;
Skorpen, Frank;
Akbari, Mansour.
(2003)
Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA.
Nature
Academic article
-
Olsen, Ann-Karin;
Duale, Nur;
Bjørås, Magnar;
Larsen, Cathrine T.;
Wiger, Richard;
Holme, Jørn A..
(2003)
Limited repair of 8-hydroxy-7,8-dihydroguanine residues in human testicular cells.
Nucleic Acids Research (NAR)
Academic article
2001
-
Olsen, Ann-Karin Hardie;
Bjørntuft, Helle;
Wiger, Richard;
Holme, Jørn A.;
Seeberg, Erling Christen;
Bjørås, Magnar.
(2001)
Highly efficient Base Excision Repair (BER) in human and rat male germ cells.
Nucleic Acids Research (NAR)
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Dagens medisin
Reader opinion piece
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The role of impaired oxidative base lesion repair in Alzheimer’s disease.
Alzheimer's & Dementia
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Dissecting gene expression networks in the developing hippocampus through the lens of NEIL3 depletion.
Progress in Neurobiology
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Enhanced glutathione levels confer resistance to apoptotic and ferroptotic programmed cell death in NEIL DNA glycosylase deficient HAP1 cells.
Free Radical Biology & Medicine
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Predicting regulatory mutations and their target genes by new computational integrative analysis: A study of follicular lymphoma.
Computers in Biology and Medicine
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Genomic 8-oxoguanine modulates gene transcription independent of its repair by DNA glycosylases OGG1 and MUTYH.
Redox Biology
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Loss of alkyladenine DNA glycosylase alters gene expression in the developing mouse brain and leads to reduced anxiety and improved memory.
DNA Repair
Academic article
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The combination of pleconaril, rupintrivir, and remdesivir efficiently inhibits enterovirus infections in vitro, delaying the development of drug-resistant virus variants.
Antiviral Research
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NAxtra magnetic nanoparticles for low-cost, efficient isolation of mammalian DNA and RNA.
Scientific Reports
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Boosted production of antibodies that neutralized different SARS-CoV-2 variants in a COVID-19 convalescent following messenger RNA vaccination - a case study.
International Journal of Infectious Diseases
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A loss-of-function mutation in human Oxidation Resistance 1 disrupts the spatial–temporal regulation of histone arginine methylation in neurodevelopment.
Genome Biology
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Anthi, Aina Karen;
Kolderup, Heidi Anette;
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A pan-SARS-CoV-2-specific soluble angiotensin-converting enzyme 2-albumin fusion engineered for enhanced plasma half-life and needle-free mucosal delivery.
PNAS Nexus
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Optimization of the Hemolysis Assay for the Assessment of Cytotoxicity.
International Journal of Molecular Sciences
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Tidsskrift for Den norske legeforening (Tidsskriftet)
Article in business/trade/industry journal
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Identifying functional regulatory mutation blocks by integrating genome sequencing and transcriptome data.
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Severely ill COVID-19 patients have altered circulating levels of proteins controlling the epitranscriptome.
Journal of Infection
Letter to the editor
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Ravlo, Erlend;
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A fast, low-cost, robust and high-throughput method for viral nucleic acid isolation based on NAxtra magnetic nanoparticles.
Scientific Reports
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Proceedings of the National Academy of Sciences of the United States of America (PNAS)
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Optimized synthesis of polyacrylic acid-coated magnetic nanoparticles for high-efficiency DNA isolation and size selection.
RSC Advances
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Immobilization of FeFe-hydrogenase on black TiO2 nanotubes as biocathodes for the hydrogen evolution reaction.
Electrochemistry communications
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Biochemistry and Biophysics Reports
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Human Genetics
Article in business/trade/industry journal
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Multi-OMICs landscape of SARS-CoV-2-induced host responses in human lung epithelial cells.
iScience
Academic article
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Mono- and combinational drug therapies for global viral pandemic preparedness.
iScience
Academic literature review
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Antiviral Immunoglobulins of Chicken Egg Yolk for Potential Prevention of SARS-CoV-2 Infection.
Viruses
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Duodenal inflammation in common variable immunodeficiency has altered transcriptional response to viruses.
Journal of Allergy and Clinical Immunology
Academic article
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DrugVirus.info 2.0: an integrative data portal for broad-spectrum antivirals (BSA) and BSA-containing drug combinations (BCCs).
Nucleic Acids Research (NAR)
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Lactate receptor HCAR1 regulates neurogenesis and microglia activation after neonatal hypoxia-ischemia.
eLIFE
Academic article
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Novel Synergistic Anti-Enteroviral Drug Combinations.
Viruses
Academic article
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Seven classes of antiviral agents.
Cellular and Molecular Life Sciences (CMLS)
Academic literature review
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DNA Repair Mechanisms are Activated in Circulating Lymphocytes of Hospitalized Covid-19 Patients.
Journal of Inflammation Research
Academic article
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Age- and sex-dependent effects of DNA glycosylase Neil3 on amyloid pathology, adult neurogenesis, and memory in a mouse model of Alzheimer's disease.
Free Radical Biology & Medicine
Academic article
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Mapping of pituitary stress-induced gene regulation connects Nrcam to negative emotions.
iScience
Academic article
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Epitranscriptome in Ischemic Cardiovascular Disease: Potential Target for Therapies.
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Academic literature review
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DNA repair enzyme NEIL3 enables a stable neural representation of space by shaping transcription in hippocampal neurons.
iScience
Academic article
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Ewida, Nour;
Sousa, Mirta;
Bjørås, Magnar;
Vågbø, Cathrine Broberg.
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Insight into ALKBH8-related intellectual developmental disability based on the first pathogenic missense variant.
Human Genetics
Academic article
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Till, Katharina;
Backe, Paul Hoff;
Blicher, Pernille;
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Non-flipping DNA glycosylase AlkD scans DNA without formation of a stable interrogation complex.
Communications Biology
Academic article
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DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development.
Atherosclerosis
Academic article
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Yao, Rouan;
Zusinaite, Eva;
Lysvand, Hilde;
Oksenych, Valentyn;
Tenson, Tanel.
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Active components of commonly prescribed medicines affect influenza a virus–host cell interaction: A pilot study.
Viruses
Academic article
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Aksu, Merdane Ezgi;
Bradamante, Stefano;
Mihaljevic, Boris;
Wang, Wei;
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Increased p53 signaling impairs neural differentiation in HUWE1-promoted intellectual disabilities.
Cell Reports Medicine
Academic article
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Roba, Aklilu Abrham;
Booth, James;
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Antimicrobial resistance: A challenge awaiting the post-COVID-19 era.
International Journal of Infectious Diseases
Academic article
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NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice.
Communications Biology
Academic article
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Steen, Kristian Wollen;
Hagen, Lars;
Vågbø, Cathrine Broberg;
Rabe, Renana;
Iveland, Tobias Solli;
Aas, Per Arne.
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ALKBH3 partner ASCC3 mediates P-body formation and selective clearance of MMS-induced 1-methyladenosine and 3-methylcytosine from mRNA.
Journal of Translational Medicine
Academic article
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Yao, Rouan;
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Synergistic interferon-alpha-based combinations for treatment of sars-cov-2 and other viral infections.
Viruses
Academic article
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Ye, Jing;
Gomez, Luisa Fernanda Luna;
Hildrestrand, Gunn Annette;
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Impact of oxidative DNA damage and the role of DNA glycosylases in neurological dysfunction.
International Journal of Molecular Sciences
Academic literature review
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Chang, Soo Young;
Byun, Soo Young;
Ianevski, Aleksandr;
Choi, Inhee;
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Screening of FDA-Approved Drugs Using a MERS-CoV Clinical Isolate from South Korea Identifies Potential Therapeutic Options for COVID-19.
Viruses
Academic article
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Ianevski, Aleksandr;
Yao, Rouan;
Lysvand, Hilde;
Grødeland, Gunnveig;
Legrand, Nicolas;
Oksenych, Valentyn.
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Nafamostat–interferon-α combination suppresses sars-cov-2 infection in vitro and in vivo by cooperatively targeting host tmprss2.
Viruses
Academic article
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Ladner, Jason T.;
Henson, Sierra N.;
Boyle, Annalee S.;
Engelbrektson, Anna L.;
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Epitope-resolved profiling of the SARS-CoV-2 antibody response identifies cross-reactivity with endemic human coronaviruses.
Cell Reports Medicine
Academic article
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Zhao, Chungui;
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Synthesis and antimicrobial activities of chitosan/polypropylene carbonate-based nanoparticles.
RSC Advances
Academic article
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Montaldo, Nicola Pietro;
Aksu, Merdane Ezgi;
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(2021)
Loss of Mediator complex subunit 13 (MED13) promotes resistance to alkylation through cyclin D1 upregulation.
Nucleic Acids Research (NAR)
Academic article
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Xu, Kaiqi;
Chatzitakis, Athanasios Eleftherios;
Backe, Paul Hoff;
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In situ cofactor regeneration enables selective CO2 reduction in a stable and efficient enzymatic photoelectrochemical cell.
Applied Catalysis B: Environmental
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Huse, Camilla;
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Endonuclease v regulates atherosclerosis through c-c motif chemokine ligand 2-mediated monocyte infiltration.
Journal of the American Heart Association (JAHA)
Academic article
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Kong, Xiang Yi;
Holm, Sverre;
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(2021)
NEIL3-deficiency increases gut permeability and contributes to a pro-atherogenic metabolic phenotype.
Scientific Reports
Academic article
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Anderssen, Petter Inge;
Ianevski, Aleksandr;
Lysvand, Hilde;
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Discovery and development of safe-in-man broad-spectrum antiviral agents.
International Journal of Infectious Diseases
Academic literature review
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Jalland, Clara Maria Osnes;
Benestad, Sylvie L.;
Moldal, Torfinn;
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(2020)
DNA glycosylase Neil2 contributes to genomic responses in the spleen during clinical prion disease.
Free Radical Biology & Medicine
Academic article
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Xu, Kaiqi;
Chatzitakis, Athanasios Eleftherios;
Risbakk, Sanne;
Yang, Mingyi;
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Grandcolas, Mathieu.
(2020)
High performance and toxicity assessment of Ta3N5 nanotubes for photoelectrochemical water splitting.
Catalysis Today
Academic article
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Kong, Xiang Yi;
Vik, Erik Sebastian;
Nawaz, Meh Sameen;
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Deletion of Endonuclease V suppresses chemically induced hepatocellular carcinoma.
Nucleic Acids Research (NAR)
Academic article
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Martin-Hernandez, Kathline;
Wang, Wei;
Kunath, Nicolas;
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Parp3 promotes astrocytic differentiation through a tight regulation of Nox4-induced ROS and mTorc2 activation.
Cell Death & Disease
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Yang, Mingyi;
Lin, Xiaolin;
Segers, Filip;
Suganthan, Rajikala;
Hildrestrand, Gunn Annette;
Rinholm, Johanne Egge.
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OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation.
Cell reports
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Naeini, Alireza Sahaf;
Farooq, Amna;
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IGAP-integrative genome analysis pipeline reveals new gene regulatory model associated with nonspecific TF-DNA binding affinity.
Computational and Structural Biotechnology Journal
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Ianevski, Aleksandr;
Yao, Rouan;
Fenstad, Mona H.;
Biza, Svetlana;
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Potential Antiviral Options against SARS-CoV-2 Infection. Viruses.
Viruses
Academic article
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Nedal, Aina;
Ræder, Synnøve Brandt;
Dalhus, Bjørn;
Helgesen, Emily;
Forstrøm, Rune Johansen;
Lindland, Kim.
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Peptides containing the PCNA interacting motif APIM
bind to the beta-clamp and inhibit bacterial growth and
mutagenesis.
Nucleic Acids Research (NAR)
Academic article
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Lærdahl, Jon Kristen;
Kittelsen, Lene Svendsen;
Dalhus, Bjørn;
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Structural basis for substrate and product recognition in human phosphoglucomutase-1 (PGM1) isoform 2, a member of the α-D-phosphohexomutase superfamily.
Scientific Reports
Academic article
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Lobie, Tekle Airgecho;
Woldeamanuel, Yimtubezinash;
Asrat, Daniel;
Beyene, Demissew Balcha;
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Aseffa, Abraham.
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Genetic diversity and drug resistance pattern of Mycobacterium tuberculosis strains isolated from pulmonary tuberculosis patients in the Benishangul Gumuz region and its surroundings, Northwest Ethiopia.
PLOS ONE
Academic article
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Louwe, Maria Cornelia;
Olsen, Maria Belland;
Kaasbøll, Ole Jørgen;
Yang, Kuan;
Fosshaug, Linn Elisabeth Lillerud;
Alfsnes, Katrine.
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Absence of NLRP3 Inflammasome in Hematopoietic Cells Reduces Adverse Remodeling After Experimental Myocardial Infarction.
JACC: Basic to Translational Science
Academic article
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Farooq, Amna;
Grønmyr, Sindre;
Omer, Ali Avan;
Rognes, Torbjørn;
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HMST-Seq-Analyzer: A new python tool for differential methylation and hydroxymethylation analysis in various DNA methylation sequencing data.
Computational and Structural Biotechnology Journal
Academic article
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Quiles Jimenez, Ana Maria Teresa;
Gregersen, Ida;
Sousa, Mirta;
Abbas, Azhar;
Kong, Xiang Yi;
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N6-methyladenosine in RNA of atherosclerotic plaques: An epitranscriptomic signature of human carotid atherosclerosis.
Biochemical and Biophysical Research Communications - BBRC
Academic article
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Polec, Anna;
Rowe, Alexander D.;
Blicher, Pernille;
Suganthan, Rajikala;
Bjørås, Magnar;
Bøe, Stig Ove.
(2020)
PML regulates the epidermal differentiation complex and skin morphogenesis during mouse embryogenesis.
Genes
Academic article
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Ianevski, Aleksandr;
Yao, Rouan;
Biza, Svetlana;
Zusinaite, Eva;
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Kivi, Gaily.
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Identification and Tracking of Antiviral Drug Combinations.
Viruses
Academic article
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Bjørås, Magnar.
(2020)
Nobelpris for oppdagelse av hvordan celler tilpasser seg skiftende oksygennivå.
Tidsskrift for Den norske legeforening (Tidsskriftet)
Editorial
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Špírek, Mário;
Lobie, Tekle Airgecho;
Skarstad, Kirsten Jane;
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Antibiotic-induced DNA damage results in a controlled loss of pH homeostasis and genome instability.
Scientific Reports
Academic article
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Chemical, Physical and Biological Triggers of Evolutionary Sonserved Bcl-xL-Mediated Apoptosis.
Cancers
Academic article
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Rognlien, Anne Gro Wesenberg;
Wollen, Embjørg Julianne;
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Neonatal Ogg1/Mutyh knockout mice have altered inflammatory gene response compared to wildtype mice in the brain and lung after hypoxia-reoxygenation.
Journal of Perinatal Medicine
Academic article
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Expanding the activity spectrum of antiviral agents.
Drug Discovery Today
Academic literature review
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Publisher Correction: Breaking the speed limit with multimode fast scanning of DNA by Endonuclease V (Nature Communications, (2018), 9, 1, (5381), 10.1038/s41467-018-07797-4).
Nature Communications
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Ystgaard, Martin Bogale;
Scheffler, Katja;
Suganthan, Rajikala;
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Neuromodulatory effect of NLRP3 and ASC in neonatal hypoxic ischemic encephalopathy.
Neonatology
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(2019)
Diverse functions of DNA glycosylases processing oxidative base lesions in brain.
DNA Repair
Academic literature review
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Berges, Natalia;
Nawaz, Meh Sameen;
Dahl, Tuva Børresdatter;
Hagen, Lars;
Bjørås, Magnar;
Lærdahl, Jon Kristen.
(2019)
Complex alternative splicing of human Endonuclease V mRNA, but evidence for only a single protein isoform.
PLOS ONE
Academic article
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Montaldo, Nicola Pietro;
Bordin, Diana Lilian;
Brambilla, Alessandro;
Rösinger, Marcel;
Martin, Sarah Fordyce;
Bjørås, Karine Øian.
(2019)
Alkyladenine DNA glycosylase associates with transcription elongation to coordinate DNA repair with gene expression.
Nature Communications
Academic article
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Ahmadi, Arash;
Till, Katharina;
Hafting, Yngve;
Schuttpelz, Mark;
Bjørås, Magnar;
Glette, Kyrre.
(2019)
Additive manufacturing of laminar flow cells for single-molecule experiments.
Scientific Reports
Academic article
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Zhang, Zhichao;
Manaf, Adeel;
Li, Yanjiao;
Pérez, Sonia Peña;
Suganthan, Rajikala;
Dahl, John Arne.
(2019)
Histone methylations define neural stem/progenitor cell subtypes in the mouse subventricular zone.
Molecular Neurobiology
Academic article
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Castaneda Zegarra, Sergio Miguel ;
Huse, Camilla;
Røsand, Øystein;
Sarno, Antonio;
Xing, Mengtan;
Gago-Fuentes, Raquel.
(2019)
Generation of a mouse model lacking the non-homologous end-joining factor Mri/Cyren.
Biomolecules
Academic article
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Li, Xiang;
Zhao, Qiongyi;
Wei, Wei;
Lin, Quan;
Magnan, Christophe;
Emami, Michael R.
(2019)
The DNA modification N6-methyl-2 '-eoxyadenosine (m6dA) drives activity-induced gene expression and is required for fear extinction.
Nature Neuroscience
Academic article
-
Anderssen, Petter Inge;
Krpina, Klara;
Ianevski, Aleksandr;
Shtaida, Nastassia;
Jo, Eunji;
Yang, Jaewon.
(2019)
Novel antiviral activities of obatoclax, emetine, niclosamide, brequinar, and homoharringtonine.
Viruses
Academic article
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Bösl, Korbinian;
Ianevski, Aleksandr;
Than, Thoa T.;
Anderssen, Petter Inge;
Kuivanen, Suvi;
Teppor, Mona.
(2019)
Common nodes of virus-host interaction revealed through an integrated network analysis.
Frontiers in Immunology
Academic article
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Askeland, Georgina;
Rodinova, Marie;
Štufková, Hana;
Dosoudilova, Zaneta;
Baxa, Monika;
Smatlikova, Petra.
(2018)
A transgenic minipig model of Huntington's disease shows early signs of behavioral and molecular pathologies.
Disease Models and Mechanisms
Academic article
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Zusinaite, Eva;
Ianevski, Aleksandr;
Niukkanen, Diana;
Poranen, Minna M.;
Bjørås, Magnar;
Afset, Jan Egil.
(2018)
A systems approach to study immuno- and neuro-modulatory properties of antiviral agents.
Viruses
Academic literature review
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Reiten, Malin Rokseth;
Malachin, Giulia;
Kommisrud, Elisabeth;
Østby, Gunn Charlotte;
Waterhouse, Karin Elisabeth;
Krogenæs, Anette Kristine.
(2018)
Stress resilience of spermatozoa and blood mononuclear cells without prion protein.
Frontiers in Molecular Biosciences
Academic article
-
Askeland, Georgina;
Dosoudilova, Zaneta;
Rodinova, Marie;
Klempir, Jiri;
Liskova, Irena;
Kusnierczyk, Anna.
(2018)
Increased nuclear DNA damage precedes mitochondrial dysfunction in peripheral blood mononuclear cells from Huntington's disease patients.
Scientific Reports
Academic article
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Ahmadi, Arash;
Rosnes, Ida;
Blicher, Pernille;
Diekmann, Robin;
Schüttpelz, Mark;
Glette, Kyrre.
(2018)
Breaking the speed limit with multimode fast scanning of DNA by Endonuclease V.
Nature Communications
Academic article
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Alexeeva, Marina;
Guragain, Prashanna;
Tesfahun, Almaz Nigatu;
Tomkuvienė, Miglė;
Arshad, Aysha;
Gerasimaitė, Rūta.
(2018)
Excision of the doubly methylated base N4,5-dimethylcytosine from DNA by Escherichia coli Nei and Fpg proteins
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Philosophical Transactions of the Royal Society of London. Biological Sciences
Academic article
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Li, Miaomiao;
Zhao, Xu;
Wang, Wei;
Shi, Hailing;
Pan, Qingfei;
Lu, Zhike.
(2018)
Ythdf2-mediated m6A mRNA clearance modulates neural development in mice.
Genome Biology
Academic article
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Ianevski, Aleksandr;
Zusinaite, Eva;
Kuivanen, Suvi;
Strand, Mårten;
Lysvand, Hilde;
Teppor, Mona.
(2018)
Novel activities of safe-in-human broad-spectrum antiviral agents.
Antiviral Research
Academic article
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Scheffler, Katja;
Rachek, Lyudmila;
You, Panpan;
Rowe, Alexander D.;
Wang, Wei;
Kuśnierczyk, Anna.
(2018)
8-oxoguanine DNA glycosylase (Ogg1) controls hepatic gluconeogenesis.
DNA Repair
Academic article
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Gago-Fuentes, Raquel;
Xing, Mengtan;
Sæterstad, Siri;
Sarno, Antonio;
Dewan, Alisa Elinsdatter;
Beck, Carole.
(2018)
Normal development of mice lacking PAXX, the paralogue of XRCC4 and XLF.
FEBS Open Bio
Academic article
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Bosshard, Matthias;
Aprigliano, Rossana;
Gattiker, Cristina;
Palibrk, Vuk;
Markkanen, Enni;
Backe, Paul Hoff.
(2018)
Publisher Correction: Impaired oxidative stress response characterizes HUWE1-promoted X-linked intellectual disability.
Scientific Reports
Errata
-
Bjørås, Karine;
Sousa, Mirta;
Sharma, Animesh;
Fonseca, Davi de Miranda;
Søgaard, Caroline Danielsen;
Bjørås, Magnar.
(2017)
Monitoring of the spatial and temporal dynamics of BER/SSBR pathway proteins, including MYH, UNG2, MPG, NTH1 and NEIL1-3, during DNA replication.
Nucleic Acids Research (NAR)
Academic article
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Morland, Cecilie;
Andersson, Krister;
Haugen, Øyvind Pernell;
Hadzic, Alena;
Kleppa, Liv;
Gille, Andreas.
(2017)
Exercise induces cerebral VEGF and angiogenesis via the lactate receptor HCAR1.
Nature Communications
Academic article
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Rolseth, Veslemøy;
Gomez, Luisa Fernanda Luna;
Olsen, Ann-Karin;
Suganthan, Rajikala;
Scheffler, Katja;
Neurauter, Christine Gran.
(2017)
No cancer predisposition or increased spontaneous mutation frequencies in NEIL DNA glycosylases-deficient mice.
Scientific Reports
Academic article
-
Batmanov, Kirill;
Wang, Wei;
Bjørås, Magnar;
Delabie, Jan;
Wang, Junbai.
(2017)
Integrative whole-genome sequence analysis reveals roles of regulatory mutations in BCL6 and BCL2 in follicular lymphoma.
Scientific Reports
Academic article
-
Xing, Mengtan;
Bjørås, Magnar;
Daniel, Jeremy A.;
Alt, Frederick W.;
Oksenych, Valentyn.
(2017)
Synthetic lethality between murine DNA repair factors XLF and DNA-PKcs is rescued by inactivation of Ku70.
DNA Repair
Academic article
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Ottesen, Anett Hellebø;
Carlson, Cathrine Rein;
Louch, William Edward;
Dahl, Mai Britt;
Sandbu, Ragnhild Askeland;
Johansen, Rune Forstrøm.
(2017)
Glycosylated Chromogranin A in Heart Failure: Implications for Processing and Cardiomyocyte Calcium Homeostasis.
Circulation: Heart Failure
Academic article
-
Olsen, Maria Belland;
Hildrestrand, Gunn Annette;
Scheffler, Katja;
Vinge, Leif Erik;
Alfsnes, Katrine;
Palibrk, Vuk.
(2017)
NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture.
Cell reports
Academic article
-
Rydning, Siri Lynne;
Backe, Paul Hoff;
Sousa, Mirta;
Iqbal, Zafar;
Øye, Ane-Marte;
Sheng, Ying.
(2017)
Novel UCHL1 mutations reveal new insights into ubiquitin processing.
Human Molecular Genetics
Academic article
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Pawar, Tina;
Bjørås, Magnar;
Klungland, Arne;
Eide, Lars.
(2017)
Metabolism and DNA repair shape a specific modification pattern in mitochondrial DNA.
Mitochondrion (Amsterdam. Print)
Academic article
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Bosshard, Matthias;
Aprigliano, Rossana;
Gattiker, Cristina;
Palibrk, Vuk;
Markkanen, Enni;
Backe, Paul Hoff.
(2017)
Impaired oxidative stress response characterizes HUWE1-promoted X-linked intellectual disability.
Scientific Reports
Academic article
-
Rydning, Siri Lynne;
Backe, Paul Hoff;
Sousa, Mirta;
Iqbal, Zafar;
Øye, Ane-Marte;
Sheng, Ying.
(2017)
Corrigendum: Novel UCHL1 mutations reveal new insights into ubiquitin processing.
Human Molecular Genetics
Errata
-
Skarpengland, Tonje;
Holm, Sverre;
Scheffler, Katja;
Gregersen, Ida;
Dahl, Tuva Børresdatter;
Suganthan, Rajikala.
(2016)
Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice.
Scientific Reports
Academic article
-
Petrova, Lucy;
Neurauter, Christine Gran;
Bjørås, Magnar;
Doetsch, Paul W.
(2016)
Efficient and Reliable Production of Vectors for the Study of the Repair, Mutagenesis, and Phenotypic Consequences of Defined DNA Damage Lesions in Mammalian Cells.
PLOS ONE
Academic article
-
Nawaz, Meh Sameen;
Vik, Erik Sebastian;
Berges, Natalia;
Fladeby, Cathrine;
Bjørås, Magnar;
Dalhus, Bjørn.
(2016)
Regulation of Human Endonuclease V Activity and Relocalization to Cytoplasmic Stress Granules.
Journal of Biological Chemistry
Academic article
-
Palibrk, Vuk;
Suganthan, Rajikala;
Scheffler, Katja;
Wang, Wei;
Bjørås, Magnar;
Bøe, Stig Ove.
(2016)
PML regulates neuroprotective innate immunity and neuroblast commitment in a hypoxic–ischemic encephalopathy model.
Cell Death & Disease
Academic article
-
Jalland, Clara Maria Osnes;
Scheffler, Katja;
Benestad, Sylvie Lafond;
Moldal, Torfinn;
Ersdal, Cecilie;
Gunnes, Gjermund.
(2016)
Neil3 induced neurogenesis protects against prion disease during the clinical phase.
Scientific Reports
Academic article
-
Benterud, Torkil;
Ystgaard, Martin Bogale;
Manueldas, Sophia;
Pankratov, Leonid;
Alfaro-Cervello, Clara;
Florholmen, Geir.
(2016)
N-Acetylcysteine Amide Exerts Possible Neuroprotective Effects in Newborn Pigs after Perinatal Asphyxia.
Neonatology
Academic article
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Dahl, John Arne;
Jung, Inkyung;
Aanes, Håvard;
Greggains, Gareth;
Manaf, Adeel;
Lerdrup, Mads.
(2016)
Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.
Nature
Academic article
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Kristiansen, Knut Ivan;
Weel-Sneve, Ragnhild;
Booth, James;
Bjørås, Magnar.
(2016)
Mutually exclusive RNA secondary structures regulate translation initiation of DinQ in Escherichia coli.
RNA: A publication of the RNA Society
Academic article
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Xue, JH;
Xu, GF;
Gu, TP;
Chen, GD;
Han, BB;
Xu, ZM.
(2016)
Uracil-DNA glycosylase UNG promotes tet-mediated DNA demethylation.
Journal of Biological Chemistry
Academic article
-
Nawaz, Meh Sameen;
Vik, Erik Sebastian;
Ronander, Mia Elise;
Solvoll, Anne Marthe;
Blicher, Pernille;
Bjørås, Magnar.
(2016)
Crystal structure and MD simulation of mouse EndoV reveal wedge motif plasticity in this inosine-specific endonuclease.
Scientific Reports
Academic article
-
Schürmann, David;
Scheidegger, Simon P.;
Weber, Alain R.;
Bjørås, Magnar;
Leumann, Christian J.;
Schär, Primo.
(2016)
3CAPS - A structural AP-site analogue as a tool to investigate DNA base excision repair.
Nucleic Acids Research (NAR)
Academic article
-
Skarpengland, Tonje;
Dahl, Tuva Børresdatter;
Skjelland, Mona;
Scheffler, Katja;
Sousa, Mirta;
Gregersen, Ida.
(2016)
Enhanced base excision repair capacity in carotid atherosclerosis may protect nuclear DNA but not mitochondrial DNA.
Free Radical Biology & Medicine
Academic article
-
Bliksøen, Marte;
Baysa, Anton;
Eide, Lars;
Bjørås, Magnar;
Suganthan, Rajikala;
Vaage, Ingvar Jarle.
(2015)
Mitochondrial DNA damage and repair during ischemia-reperfusion injury of the heart.
Journal of Molecular and Cellular Cardiology
Academic article
-
Yang, Mingyi;
Lin, Xiaolin;
Rowe, Alexander D.;
Rognes, Torbjørn;
Eide, Lars;
Bjørås, Magnar.
(2015)
Transcriptome analysis of human OXR1 depleted cells reveals its role in regulating the p53 signaling pathway.
Scientific Reports
Academic article
-
Lundin, Karin E.;
Hamasy, Abdulrahman;
Backe, Paul Hoff;
Moens, Lotte N.;
Falk-Sörqvist, Elin;
Elgstøen, Katja B. Prestø.
(2015)
Susceptibility to infections, without concomitant hyper-IgE, reported in 1976, is caused by hypomorphic mutation in the phosphoglucomutase 3 (PGM3) gene.
Clinical Immunology
Academic article
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Bjørge, Monica Dahl;
Hildrestrand, Gunn Annette;
Scheffler, Katja;
Suganthan, Rajikala;
Rolseth, Veslemøy;
Kusnierczyk, Anna.
(2015)
Synergistic Actions of Ogg1 and Mutyh DNA Glycosylases Modulate Anxiety-like Behavior in Mice.
Cell reports
Academic article
-
Skarpengland, Tonje;
Laugsand, Lars Erik;
Janszky, Imre;
Gomez, Luisa Fernanda Luna;
Halvorsen, Bente;
Platou, Carl Geoffrey Parrinder.
(2015)
Genetic variants in the DNA repair gene NEIL3 and the risk of myocardial infarction in a nested case-control study. The HUNT Study.
DNA Repair
Academic article
-
Booth, James;
Suganthan, Rajikala;
Gaustad, Peter;
Bjørås, Magnar.
(2015)
Development of DinQ from Escherichia coli as an anti-cell-envelope antibiotic.
International Journal of Antimicrobial Agents
Letter to the editor
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Ottesen, Anett Hellebø;
Carlson, Cathrine Rein;
Edwards, Andrew;
Landsverk, Ole J. B.;
Johansen, Rune Forstrøm;
Moe, Morten Kaare.
(2015)
Secretoneurin,a novel endogenous CaMKII inhibitor, augments cardiomyocyte Calcium handling and inhibits arrhythmogenic Calcium release.
Biophysical Journal
Abstract
-
Dalhus, Bjørn;
Alseth, Ingrun;
Bjørås, Magnar.
(2015)
Structural basis for incision at deaminated adenines in DNA and RNA by endonuclease V.
Progress in Biophysics and Molecular Biology
Academic literature review
-
Ottesen, Anett Hellebø;
Louch, William Edward;
Carlson, Cathrine Rein;
Landsverk, Ole J. B.;
Kurola, Jouni;
Johansen, Rune Forstrøm.
(2015)
Secretoneurin is a novel prognostic cardiovascular biomarker associated with cardiomyocyte calcium handling.
Journal of the American College of Cardiology
Academic article
-
Ottesen, Anett Hellebø;
Louch, William Edward;
Carlson, Cathrine Rein;
Landsverk, Ole J. B.;
Kurola, Jouni;
Johansen, Rune Forstrøm.
(2014)
Secretoneurin provides independent prognostic information in patients with heart failure and cardiac arrest, and has a direct inhibitory effect on diastolic Ca2+ leak and arrhythmogenic Ca2+ waves via CaMKII inhibition.
Circulation Research
Abstract
-
Yang, Mingyi;
Luna, Linda;
Sørbø, Jan Gunnar;
Alseth, Ingrun;
Johansen, Rune Forstrøm;
Backe, Paul Hoff.
(2014)
Human OXR1 maintains mitochondrial DNA integrity and counteracts hydrogen peroxide-induced oxidative stress by regulating antioxidant pathways involving p21.
Free Radical Biology & Medicine
Academic article
-
Aamann, Maria D.;
Hvitby, Christina;
Popuri, Venkateswarlu;
Muftuoglu, Meltem;
Lemminger, Lasse;
Skeby, Cecilie K..
(2014)
Cockayne Syndrome group B protein stimulates NEIL2 DNA glycosylase activity.
Mechanisms of Ageing and Development
Academic article
-
Stray-Pedersen, Asbjørg;
Backe, Paul Hoff;
Sorte, Hanne Sørmo;
Mørkrid, Lars;
Chokshi, N.Y.;
Erichsen, Hans Christian.
(2014)
PGM3 mutations cause a congenital disorder of glycosylation with severe immunodeficiency and skeletal dysplasia.
American Journal of Human Genetics
Academic article
-
Jalland, Clara;
Benestad, Sylvie Lafond;
Ersdal, Cecilie;
Scheffler, Katja;
Suganthan, Rajikala;
Nakabeppu, Yusaku.
(2014)
Accelerated clinical course of prion disease in mice compromised in repair of oxidative DNA damage.
Free Radical Biology & Medicine
Academic article
-
Strand, Janne Maren;
Scheffler, Katja;
Bjørås, Magnar;
Eide, Lars.
(2014)
The distribution of DNA damage is defined by region-specific susceptibility to DNA damage formation rather than repair differences.
DNA Repair
Academic article
-
Sand, Kine Marita Knudsen;
Dalhus, Bjørn;
Christianson, Gregory J.;
Bern, Malin C.;
Foss, Stian;
Cameron, Jason.
(2014)
Dissection of the neonatal Fc receptor (FcRn)-albumin interface using mutagenesis and anti-FcRn albumin-blocking antibodies.
Journal of Biological Chemistry
Academic article
-
Andersen, Jan Terje;
Dalhus, Bjørn;
Viuff, Dorthe;
Ravn, Birgitte Thue;
Gunnarsen, Kristin Støen;
Plumridge, Andrew.
(2014)
Extending serum half-life of albumin by engineering neonatal Fc receptor (FcRn) binding.
Journal of Biological Chemistry
Academic article
-
Alseth, Ingrun;
Dalhus, Bjørn;
Bjørås, Magnar.
(2014)
Inosine in DNA and RNA.
Current Opinion in Genetics and Development
Academic literature review
-
Maier, Lukas;
Hylse, Ondrej;
Necas, Marek;
Trbusek, Martin;
Ytre-Arne, Mari;
Dalhus, Bjørn.
(2014)
New carbocyclic nucleosides: Synthesis of carbocyclic pseudoisocytidine and its analogs.
Tetrahedron Letters
Academic article
-
Strand, Janne Maren;
Skinnes, Ragnhild;
Scheffler, Katja;
Rootwelt, Terje;
Woldseth, Berit;
Bjørås, Magnar.
(2014)
Genome instability in Maple Syrup Urine Disease correlates with impaired mitochondrial biogenesis.
Metabolism: Clinical and Experimental
Academic article
-
Wang, Wei;
Scheffler, Katja;
Esbensen, Qin Ying;
Strand, Janne Maren;
Stewart, James B.;
Bjørås, Magnar.
(2014)
Addressing RNA integrity to determine the impact of mitochondrial DNA mutations on brain mitochondrial function with age.
PLOS ONE
Academic article
-
Sand, Kine Marita Knudsen;
Dalhus, Bjørn;
Christianson, Gregory J.;
Bern, Malin C.;
Foss, Stian;
Cameron, Jason.
(2014)
Dissection of the neonatal Fc receptor (FcRn)-albumin interface using mutagenesis and anti-FcRn albumin-blocking antibodies.
Journal of Biological Chemistry
Academic article
-
Zimmermann, Christine;
Santos, Aline;
Gable, Kenneth;
Epstein, Sharon;
Gururaj, Charulatha;
Chymkowitch, Pierre.
(2013)
TORC1 Inhibits GSK3-Mediated Elo2 Phosphorylation to Regulate Very Long Chain Fatty Acid Synthesis and Autophagy.
Cell reports
Academic article
-
Bousquet, Paula;
Abshiru, Nebiyu;
Johansen, Rune Forstrøm;
Bjørås, Magnar;
Sandvik, Joe Alexander;
Pettersen, Erik O.
(2013)
A structural and functional study of anti-ganglioside antibodies.
International Journal of Molecular Medicine
Abstract
-
Booth, James A.;
Thomassen, Gard O Sundby;
Rowe, Alexander D.;
Weel-Sneve, Ragnhild;
Lagesen, Karin;
Kristiansen, Knut Ivan.
(2013)
Tiling array study of MNNG treated Escherichia coli reveals a widespread transcriptional response.
Scientific Reports
Academic article
-
Ottesen, Anett Hellebø;
Louch, William Edward;
Carlson, Cathrine Rein;
Landsverk, Ole J. B.;
Johansen, Rune forstrom;
Moe, Morten.
(2013)
Secretoneurin is a novel endogenous CaMKII inhibitor that regulates cardiomyocyte calcium handling and is closely associated with mortality in patients with acute heart failure.
Circulation
Abstract
-
Backe, Paul Hoff;
Simm, Roger;
Lærdahl, Jon Kristen;
Dalhus, Bjørn;
Fagerlund, Annette;
Økstad, Ole Andreas Løchen.
(2013)
A new family of proteins related to the HEAT-like repeat DNA glycosylases with affinity for branched DNA structures.
Journal of Structural Biology
Academic article
-
Simonelli, V;
Camerini, S;
Mazzei, F;
Van Loon, B;
Allione, A;
D'Errico, M.
(2013)
Genotype-phenotype analysis of S326C OGG1 polymorphism: a risk factor for oxidative pathologies.
Free Radical Biology & Medicine
Academic article
-
Rognlien, Anne Gro Wesenberg;
Wollen, Embjørg Julianne;
Bjørås, Magnar;
Saugstad, Ola Didrik.
(2013)
DNA Glycosylases Protect the Newborn Mouse Lung from Apoptosis, Cell Cycle Arrest and Inflammation.
Neonatology
Abstract
-
Rosnes, Ida;
Rowe, Alexander D.;
Vik, Erik Sebastian;
Johansen, Rune Forstrøm;
Alseth, Ingrun;
Bjørås, Magnar.
(2013)
Structural Basis of DNA Loop Recognition by Endonuclease V.
Structure
Academic article
-
Weel-Sneve, Ragnhild;
Kristiansen, Knut Ivan;
Odsbu, Ingvild;
Dalhus, Bjørn;
Booth, James;
Rognes, Torbjørn.
(2013)
Single Transmembrane Peptide DinQ Modulates Membrane-Dependent Activities.
PLoS Genetics
Academic article
-
Dalhus, Bjørn;
Nilsen, Line;
Korvald, Hanne;
Huffman, Joy;
Johansen, Rune Forstrøm;
McMurray, Cynthia T..
(2013)
Sculpting of DNA at Abasic Sites by DNA Glycosylase Homolog Mag2.
Structure
Academic article
-
Bliksrud, Yngve Thomas;
Ellingsen, Amund;
Bjørås, Magnar.
(2013)
Fumarylacetoacetate inhibits the initial step of the base excision repair pathway: implication for the pathogenesis of tyrosinemia type I.
The Journal of Inherited Metabolic Disease (JIMD)
Academic article
-
Backe, Paul Hoff;
Ytre-Arne, Mari;
Røhr, Åsmund Kjendseth;
Brodtkorb, Else;
Fowler, Brian;
Rootwelt, Helge.
(2013)
Novel Deletion Mutation Identified in a Patient with Late-Onset Combined Methylmalonic Acidemia and Homocystinuria, cblC Type.
JIMD Reports
Academic article
-
Rolseth, Veslemøy;
Krokeide, Silje Z;
Kunke, David;
Neurauter, Christine Gran;
Suganthan, Rajikala;
Sejersted, Yngve.
(2013)
Loss of Neil3, the major DNA glycosylase activity for removal of hydantoins in single stranded DNA, reduces cellular proliferation and sensitizes cells to genotoxic stress.
BBA - Molecular Cell Research
Academic article
-
Krokan, Hans Einar;
Bjørås, Magnar.
(2013)
Base Excision Repair.
Cold Spring Harbor Perspectives in Biology
Academic article
-
Simonelli, Valeria;
Camerini, Serena;
Mazzei, Filomena;
Loon, Barbara Van;
Allione, Alessandra;
Mariarosaria, D'Errico.
(2013)
Genotype–phenotype analysis of S326C OGG1 polymorphism: a risk factor for oxidative pathologies.
Free Radical Biology & Medicine
Academic article
-
Krokeide, Silje Zandstra;
Lærdahl, Jon Kristen;
Salah, Medya;
Luna, Luisa;
Cederkvist, Fritjof Henning;
Fleming, Aaron M..
(2013)
Human NEIL3 is mainly a monofunctional DNA glycosylase removing spiroimindiohydantoin and guanidinohydantoin.
DNA Repair
Academic article
-
Zhang, Xiao;
Shi, Ming;
Bjørås, Magnar;
Wang, Wei;
Zhang, Guangyun;
Han, Junliang.
(2013)
Ginsenoside Rd promotes glutamate clearance by up-regulating glial glutamate transporter GLT-1 via PI3K/AKT and ERK1/2 pathways.
Frontiers in Pharmacology
Academic article
-
Jobert, Laure;
Skjeldam, Hanne Kim;
Dalhus, Bjørn;
Galashevskaya, Anastasia;
Vågbø, Cathrine Broberg;
Bjørås, Magnar.
(2013)
The human base excision repair enzyme SMUG1 directly interacts with DKC1 and contributes to RNA quality control.
Molecular Cell
Academic article
-
Vik, Erik Sebastian;
Nawaz, Meh Sameen;
Andersen, Pernille Strøm;
Fladeby, Cathrine;
Bjørås, Magnar;
Dalhus, Bjørn.
(2013)
Endonuclease V cleaves at inosines in RNA.
Nature Communications
Academic article
-
Andersen, Jan Terje;
Dalhus, Bjørn;
Cameron, Jason;
Daba, Muluneh Bekele;
Plumridge, Andrew;
Evans, Leslie.
(2012)
Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor.
Nature Communications
Academic article
-
Hudecova, Alexandra;
Kusznierewicz, Barbara;
Rundén-Pran, Elise;
Magdolenova, Zuzana;
Hasplova, Katarina;
Rinna, Alessandra.
(2012)
Silver nanoparticles induce premutagenic DNA oxidation that can be prevented by phytochemicals from Gentiana asclepiadea.
Mutagenesis
Academic article
-
Nilsen, Line;
Forstrøm, Rune Johansen;
Bjørås, Magnar;
Alseth, Ingrun.
(2012)
AP endonuclease independent repair of abasic sites in Schizosaccharomyces pombe.
Nucleic Acids Research (NAR)
Academic article
-
Hasplova, Katarina;
Hudecova, Alexandra;
Magdolenova, Zuzana;
Bjørås, Magnar;
Galova, Eliska;
Miadokova, Eva.
(2012)
DNA alkylation lesions and their repair in human cells: Modification of the comet assay with 3-methyladenine DNA glycosylase (AlkD).
Toxicology Letters
Academic article
-
Halsne, Ruth;
Esbensen, Qin Ying;
Wang, Wei;
Scheffler, Katja;
Suganthan, Rajikala;
Bjørås, Magnar.
(2012)
Lack of the DNA glycosylases MYH and OGG1 in the cancer prone double mutant mouse does not increase mitochondrial DNA mutagenesis.
DNA Repair
Academic article
-
Vaaje-Kolstad, Gustav;
Bøhle, Liv Anette;
Gåseidnes, Sigrid;
Dalhus, Bjørn;
Bjørås, Magnar;
Mathiesen, Geir.
(2012)
Characterization of the Chitinolytic Machinery of Enterococcus faecalis V583 and High-Resolution Structure of Its Oxidative CBM33 Enzyme.
Journal of Molecular Biology (JMB)
Academic article
-
Søberg, Kristoffer;
Larsen, Anja C V;
Diskar, Mandy;
Backe, Paul Hoff;
Bjørås, Magnar;
Jahnsen, Tore.
(2012)
Identification and Characterization of Novel Mutations in the Human Gene Encoding the Catalytic Subunit Calpha of Protein Kinase A (PKA).
PLOS ONE
Academic article
-
Hereng, Tuva Holt;
Backe, Paul Hoff;
Kahmann, Jan;
Scheich, Christoph;
Bjørås, Magnar;
Skålhegg, Bjørn Steen.
(2012)
Structure and function of the human sperm-specific isoform of protein kinase A (PKA) catalytic subunit C alpha 2.
Journal of Structural Biology
Academic article
-
Fladeby, Cathrine;
Vik, Erik Sebastian;
Lærdahl, Jon Kristen;
Neurauter, Christine Gran;
Heggelund, Julie Elisabeth;
Thorgaard, Eirik.
(2012)
The Human Homolog of Escherichia coli Endonuclease V Is a Nucleolar Protein with Affinity for Branched DNA Structures.
PLOS ONE
Academic article
-
Rognlien, Anne Gro Wesenberg;
Wollen, Embjørg Julianne;
Atneosen-Åsegg, Monica;
Bjørås, Magnar;
Saugstad, Ola Didrik.
(2012)
290 Genes Important in Inflammation, Apoptosis, Transcription Regulation and Angiogenesis are Induced in the Newborn Mouse Brain after Hypoxia-Reoxygenation (HR).
Archives of Disease in Childhood
Abstract
-
Wollen, Embjørg Julianne;
Rognlien, Anne Gro Wesenberg;
Atneosen-Åsegg, Monica;
Bjørås, Magnar;
Saugstad, Ola Didrik.
(2012)
1779 Cell Death Genes are Induced Immediately after Hypoxia-Reoxygenation (HR) in the Newborn Mouse Lung.
Archives of Disease in Childhood
Abstract
-
Zimmermann, Christine;
Chymkowitch, Pierre;
Eldholm, Vegard;
Putnam, Christopher D.;
Lindvall, Jessica M.;
Omerzu, Manja.
(2012)
A chemical-genetic screen to unravel the genetic network of CDC28/CDK1 links ubiquitin and Rad6-Bre1 to cell cycle progression.
The FASEB Journal
Abstract
-
Vik, Erik Sebastian;
Alseth, Ingrun;
Forsbring, Monika;
Helle, Ina Høydal;
Morland, Ingrid;
Luna, Luisa.
(2012)
Biochemical mapping of human NEIL1 DNA glycosylase and AP lyase activities.
DNA Repair
Academic article
-
Payne, Christina M.;
Baban, Jamil;
Horn, Svein Jarle;
Backe, Paul Hoff;
Arvai, Andrew S.;
Dalhus, Bjørn.
(2012)
Hallmarks of processivity in glycoside hydrolases from crystallographic and computational studies of the Serratia marcescens chitinases.
Journal of Biological Chemistry
Academic article
-
Ranneberg-Nilsen, Toril;
Rollag, Halvor;
Slettebakk, Ragnhild;
Backe, Paul Hoff;
Olsen, Øyvind;
Luna, Luisa.
(2012)
The Chromatin Remodeling Factor SMARCB1 Forms a Complex with Human Cytomegalovirus Proteins UL114 and UL44.
PLOS ONE
Academic article
-
Saugstad, Ola Didrik;
Sejersted, Yngve;
Solberg, Rønnaug;
Wollen, Embjørg Julianne;
Bjørås, Magnar.
(2012)
Oxygenation of the Newborn: A Molecular Approach.
Neonatology
Academic article
-
Møllersen, Linda;
Rowe, Alexander D.;
Illuzzi, Jennifer L.;
Hildrestrand, Gunn Annette;
Gerhold, Katharina J.;
Tveterås, Linda Augustin.
(2012)
Neil1 is a genetic modifier of somatic and germline CAG trinucleotide repeat instability in R6/1 mice.
Human Molecular Genetics
Academic article
-
Neurauter, Christine Gran;
Luna, Luisa;
Bjørås, Magnar.
(2012)
Release from quiescence stimulates the expression of human NEIL3 under the control of the Ras dependent ERK-MAP kinase pathway.
DNA Repair
Academic article
-
Korvald, Hanne;
Falnes, Pål;
Lærdahl, Jon Kristen;
Bjørås, Magnar;
Alseth, Ingrun.
(2012)
The Schizosaccharomyces pombe AlkB homolog Abh1 exhibits AP lyase activity but no demethylase activity.
DNA Repair
Academic article
-
Regnell, Christine E;
Hildrestrand, Gunn Annette;
Sejersted, Yngve;
Medin, Tirill;
Moldestad, Olve;
Rolseth, Veslemøy.
(2012)
Hippocampal Adult Neurogenesis Is Maintained by Neil3-Dependent Repair of Oxidative DNA Lesions in Neural Progenitor Cells.
Cell reports
Academic article
-
Lång, Emma Helena;
Grudic, Amra;
Pankiv, Serhiy;
Bruserud, Øystein;
Simonsen, Anne;
Bjerkvig, Rolf.
(2012)
The arsenic-based cure of acute promyelocytic leukemia promotes cytoplasmic sequestration of PML and PML/RARA through inhibition of PML body recycling.
Blood
Academic article
-
Chymkowitch, Pierre;
Eldholm, Vegard;
Lorenz, Susanne;
Zimmermann, Christine;
Lindvall, Jessica M.;
Bjørås, Magnar.
(2012)
Cdc28 kinase activity regulates the basal transcription machinery at a subset of genes.
Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Academic article
-
Dalhus, Bjørn;
Forsbring, Monika;
Helle, Ina Høydal;
Vik, Erik Sebastian;
Johansen, Rune Forstrøm;
Backe, Paul Hoff.
(2011)
Separation-of-Function Mutants Unravel the Dual-Reaction Mode of Human 8-Oxoguanine DNA Glycosylase.
Structure
Academic article
-
Arczewska, Katarzyna;
Baumeier, Christian;
Kassahun, Henok;
Sengupta, Tanima;
Bjørås, Magnar;
Kuśmierek, Jarosław T..
(2011)
Caenorhabditis elegans NDX-4 is a MutT-type enzyme that contributes to genomic stability.
DNA Repair
Academic article
-
Lauritzen, Knut Husø;
Dalhus, Bjørn;
Storm, Johan Frederik;
Bjørås, Magnar;
Klungland, Arne.
(2011)
Modeling the impact of mitochondrial DNA damage in forebrain neurons and beyond.
Mechanisms of Ageing and Development
Academic article
-
Wang, Wei;
Esbensen, Ying;
Kunke, David;
Suganthan, Rajikala;
Rachek, Lyudmila;
Bjørås, Magnar.
(2011)
Mitochondrial DNA Damage Level Determines Neural Stem Cell Differentiation Fate.
Journal of Neuroscience
Academic article
-
Sejersted, Yngve;
Hildrestrand, Gunn Annette;
Kunke, David;
Rolseth, Veslemøy;
Krokeide, Silje Z.;
Neurauter, Christine Gran.
(2011)
Endonuclease VIII-like 3 (Neil3) DNA glycosylase promotes neurogenesis induced by hypoxia-ischemia.
Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Academic article
-
Zimmermann, Christine;
Chymkowitch, Pierre;
Eldholm, Vegard;
Putnam, Christopher D.;
Lindvall, Jessica Margareta;
Omerzu, Manja.
(2011)
A chemical-genetic screen to unravel the genetic network of CDC28/CDK1 links ubiquitin and Rad6-Bre1 to cell cycle progression.
Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Academic article
-
Korvald, Hanne;
Moe, Anne Margrethe Mølstad;
Cederkvist, Fritjof Henning;
Thiede, Bernd;
Lærdahl, Jon Kristen;
Bjørås, Magnar.
(2011)
Schizosaccharomyces pombe Ofd2 Is a Nuclear 2-Oxoglutarate and Iron Dependent Dioxygenase Interacting with Histones.
PLOS ONE
Academic article
-
Johnsen, Line;
Flåtten, Ingvild;
Morigen, Morigen;
Dalhus, Bjørn;
Bjørås, Magnar;
Waldminghaus, Torsten.
(2011)
The G157C mutation in the Escherichia coli sliding clamp specifically affects initiation of replication.
Molecular Microbiology
Academic article
-
Lærdahl, Jon Kristen;
Korvald, Hanne;
Nilsen, Line;
Dahl-Michelsen, Kristin;
Rognes, Torbjørn;
Bjørås, Magnar.
(2011)
Schizosaccharomyces pombe encodes a mutated AP endonuclease 1.
DNA Repair
Academic article
-
Yang, Mingyi;
Aamodt, Randi;
Dalhus, Bjørn;
Balasingham, Seetha ;
Helle, Ina Høydal;
Andersen, Pernille Strøm.
(2011)
The ada operon of Mycobacterium tuberculosis encodes two DNA methyltransferases for inducible repair of DNA alkylation damage.
DNA Repair
Academic article
-
Arczewska, Katarzyna;
Baumeier, Christian;
Kassahun, Henok;
Sengupta, Tanima;
Bjørås, Magnar;
Kuśmierek, Jarosław T..
(2010)
Caenorhabditis elegans NDX-4 is a MutT-type enzyme that contributes to genomic stability.
DNA Repair
Academic article
-
Dalen, Marit Lunde;
Alme, Tomas Nordheim;
Bjørås, Magnar;
Munkeby, Berit Holthe;
Rootwelt, Terje;
Saugstad, Ola Didrik.
(2010)
Reduced expression Of DNA glycosylases in post-hypoxic newborn pigs undergoing therapeutic hypothermia.
Brain Research
Academic article
-
Thomassen, Gard O Sundby;
Sneve, Ragnhild;
Rowe, Alexander D.;
Booth, James;
Lindvall, Jessica M.;
Lagesen, Karin.
(2010)
Tiling Array Analysis of UV Treated Escherichia coli Predicts Novel Differentially Expressed Small Peptides.
PLOS ONE
Academic article
-
Isakson, Pauline;
Bjørås, Magnar;
Bøe, Stig Ove;
Simonsen, Anne.
(2010)
Autophagy contributes to therapy-induced degradation of the PML/RARA oncoprotein.
Blood
Academic article
-
Bøyum, Arne;
Skrede, Knut Kristian;
Myhre, Oddvar;
Tennfjord, Vivi-Ann;
Neurauter, Christine Gran;
Tolleshaug, Helge.
(2010)
Calprotectin (S100A8/S100A9) and myeloperoxidase: Co-regulators of formation of reactive oxygen species.
Toxins
Academic article
-
Solberg, R.;
Andresen, Jannicke Hanne;
Borge, Grethe iren andersen;
Ellingsen, A.;
Bjørås, Magnar;
Saugstad, Ola Didrik.
(2010)
Resuscitation with 100% Oxygen Gives Increased Oxidative Stress in Lung Tissue and Influences the Capacity to Repair Base Lesions on DNA.
Neonatology
Abstract
-
Wang, Wei;
Osenbroch, Pia Madeleine Øistad;
Skinnes, Ragnhild;
Esbensen, Qin Ying;
Bjørås, Magnar;
Eide, Lars.
(2010)
Mitochondrial DNA Integrity Is Essential for Mitochondrial Maturation During Differentiation of Neural Stem Cells.
Stem Cells
Academic article
-
Brodtkorb, Else;
Strand, Janne Maren;
Backe, Paul Hoff;
Lund, Anne Marie;
Bjørås, Magnar;
Rootwelt, Terje.
(2010)
Four novel mutations identified in Norwegian patients result in intermittent maple syrup urine disease when combined with the R301C mutation.
Molecular Genetics and Metabolism
Academic article
-
Bliksrud, Yngve Thomas;
Ellingsen, Anne;
Bjørås, Magnar.
(2010)
TYROSINEMIA TYPE 1-EFFECT OF METABOLITES ON FIVE DIFFERENT DNA- REPAIR ENZYMES.
The Journal of Inherited Metabolic Disease (JIMD)
Abstract
-
Dalhus, Bjørn;
Lærdahl, Jon Kristen;
Backe, Paul Hoff;
Bjørås, Magnar.
(2009)
DNA base repair - recognition and initiation of catalysis.
FEMS Microbiology Reviews
Academic literature review
-
Hildrestrand, Gunn Annette;
Neurauter, Christine Gran;
Diep, Dzung Bao;
Castellanos, Cesilie Granum;
Krauss, Stefan;
Bjørås, Magnar.
(2009)
Expression patterns of Neil3 during embryonic brain development and neoplasia.
BMC Neuroscience
Academic article
-
Bliksrud, Yngve Thomas;
Ellingsen, Anne;
Bjørås, Magnar.
(2009)
TYROSINEMIA TYPE 1-THE DNA-REPAIR ENZYMES NEIL1 AND NEIL2 ARE INHIBITED BY FUMARYLACETOACETATE.
Molecular Genetics and Metabolism
Abstract
-
Straume, Daniel;
Johansen, Rune Forstrøm;
Bjørås, Magnar;
Nes, Ingolf F.;
Diep, Dzung Bao.
(2009)
DNA binding kinetics of two response regulators, PlnC and PlnD, from the bacteriocin regulon of Lactobacillus plantarum C11.
BMC Biochemistry
Academic article
-
Dalhus, Bjørn;
Arvai, AS;
Rosnes, Ida;
Olsen, Øyvind Edon;
Backe, Paul Hoff;
Alseth, Ingrun.
(2009)
Structures of endonuclease V with DNA reveal initiation of deaminated adenine repair.
Nature Structural & Molecular Biology
Academic article
-
Yndestad, Arne;
Neurauter, Christine Gran;
Øie, Erik;
Johansen, Rune Forstrøm;
Vinge, Leif Erik;
Eide, Lars.
(2009)
Up-regulation of myocardial DNA base excision repair activities in experimental heart failure.
Mutation research
Academic article
-
Forsbring, Monika;
Vik, Erik Sebastian;
Dalhus, Bjørn;
Karlsen, Tom Hemming;
Bergquist, A.;
Schrumpf, Erik.
(2009)
Catalytically impaired hMYH and NEIL1 mutant proteins identified in patients with primary sclerosing cholangitis and cholangiocarcinoma.
Carcinogenesis
Academic article
-
Straume, Daniel;
Johansen, Rune F;
Bjørås, Magnar;
Nes, Ingolf F.;
Diep, Dzung Bao.
(2009)
DNA binding kinetics of two response regulators, PlnC and PlnD, from the bacteriocin regulon of Lactobacillus plantarum C11.
BMC Biochemistry
Academic article
-
krokeide, Silje Z.;
Bolstad, Nils;
Lærdahl, Jon Kristen;
Bjørås, Magnar;
Luna, Luisa.
(2009)
Expression and purification of NEIL3, a human DNA glycosylase homolog.
Protein Expression and Purification
Academic article
-
Sejersted, Yngve;
Aasland, Anne Leikny;
Bjørås, Magnar;
Eide, Lars;
Saugstad, Ola Didrik.
(2009)
Accumulation of 8-Oxoguanine in Liver DNA During Hyperoxic Resuscitation of Newborn Mice.
Pediatric Research
Academic article
-
Hildrestrand, Gunn Annette;
Duggal, Shivali;
Bjørås, Magnar;
Luna, Luisa;
Brinchmann, Jan E..
(2009)
Modulation of DNA glycosylase activities in mesenchymal stem cells.
Experimental Cell Research
Academic article
-
de Jesus, BMB;
Bjørås, Magnar;
Coin, F;
Egly, JM.
(2008)
Dissection of the Molecular Defects Caused by Pathogenic Mutations in the DNA Repair Factor XPC.
Molecular and Cellular Biology
Academic article
-
Rolseth, Veslemøy;
Runden, Elise;
Luna, Gomez Luisa;
McMurray, C;
Bjørås, Magnar;
Ottersen, Ole Petter.
(2008)
Widespread distribution of DNA glycosylases removing oxidative DNA lesions in human and rodent brains.
DNA Repair
Academic article
-
Ranneberg-Nilsen, T;
Dale, HA;
Luna, L;
Slettebakk, R;
Sundheim, Ottar;
Rollag, H.
(2008)
Characterization of human cytomegalovirus uracil DNA glycosylase (UL114) and its interaction with polymerase processivity factor (UL44).
Journal of Molecular Biology (JMB)
Academic article
-
Rolseth, Veslemøy;
Runden, Elise;
Neurauter, Christine Gran;
Yndestad, Arne;
Luna, Gomez Luisa;
Aukrust, Pål.
(2008)
Base excision repair activities in organotypic hippocampal slice cultures exposed to oxygen and glucose deprivation.
DNA Repair
Academic article
-
Allunans, Juris;
Kristiansen, Knut Ivan;
Assalkhou, Reza;
Bjørås, Magnar.
(2008)
Bacteriocins (meningocins) in Norwegian isolates of Neisseria meningitidis: possible role in the course of a meningococcal epidemic.
APMIS - Journal of Pathologiy, Microbiology and Immunology
Academic article
-
Assalkhou, Reza;
Balasingham, Seetha;
Collins, RF;
Frye, Stephan Alfons;
Davidsen, Tonje;
Benam, AV.
(2007)
The outer membrane secretin PilQ from Neisseria meningitidis binds DNA.
Microbiology (Reading)
Academic article
-
Kovtun, IV;
Liu, Y;
Bjørås, Magnar;
Klungland, Arne;
Wilson, SH;
McMurray, CT.
(2007)
OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells.
Nature
Academic article
-
Dalhus, Bjørn;
Helle, Ina Høydal;
Backe, Paul Hoff;
Alseth, Ingrun;
Rognes, Torbjørn;
Bjørås, Magnar.
(2007)
Structural insight into repair of alkylated DNA by a new superfamily of DNA glycosylases comprising HEAT-like repeats.
Nucleic Acids Research (NAR)
Academic article
-
Davidsen, Tonje;
Tuven, Hanne Kim;
Bjørås, Magnar;
Rødland, Einar Andreas;
Tønjum, Tone.
(2007)
Genetic interactions of DNA repair pathways in the pathogen Neisseria meningitidis.
Journal of Bacteriology
Academic article
-
Walberg, Mette;
Mørk, Cato;
Sandven, Per;
Jorde, Anne Tomine;
Bjørås, Magnar;
Gaustad, Peter.
(2006)
18S rDNA polymerase chain reaction and sequencing in onychomycosis diagnostics.
Acta Dermato-Venereologica
Academic article
-
Ranneberg-Nilsen, Toril;
Bjørås, Magnar;
Luna, Gomez Luisa;
Slettebakk, Ragnhild;
Dale, Hege Avsnes;
Seeberg, Erling Christen.
(2006)
Human cytomegalovirus infection modulates DNA base excision repair in fibroblast cells.
Virology
Academic article
-
D'Errico, M;
Parlanti, E;
Teson, M;
de Jesus, BMB;
Degan, P;
Calcagnile, A.
(2006)
New functions of XPC in the protection of human skin cells from oxidative damage.
EMBO Journal
Academic article
-
Alseth, Ingrun;
Rognes, Torbjørn;
Lindbäck, Toril;
Solberg, Inger;
Robertsen, Kristin;
Kristiansen, Knut Ivan.
(2006)
A new protein superfamily includes two novel 3-methyladenine DNA glycosylases from Bacillus cereus, AlkC and AlkD.
Molecular Microbiology
Academic article
-
Aukrust, Pål;
Luna, Luisa;
Ueland, Thor;
Johansen, Rune Forstrøm;
Muller, Fredrik;
Frøland, Stig Sophus.
(2005)
Impaired base excision repair and accumulation of oxidative base lesions in CD4+ T cells of HIV-infected patients.
Blood
Academic article
-
Luna, Gomez Luisa;
Luna, L;
Rolseth, V;
Hildrestrand, GA;
Otterlei, Marit;
Dantzer, F.
(2005)
Dynamic relocalization of hOGG1 during the cell cycle is disrupted in cells harbouring the hOGG1-Cys(326) polymorphic variant.
Nucleic Acids Research (NAR)
Academic article
-
Davidsen, Tonje;
Bjørås, Magnar;
Seeberg, Erling Christen;
Tønjum, Tone.
(2005)
Antimutator role of DNA glycosylase MutY in pathogenic Neisseria species.
Journal of Bacteriology
Academic article
-
Morland, Ingrid;
Luna, Gomez Luisa;
Gustad, Ellen Cecilie;
Seeberg, Erling Christen;
Bjørås, Magnar.
(2005)
Product inhibition and magnesium modulate the dual reaction mode of hOgg1.
DNA Repair
Academic article
-
Falnes, Pål;
Bjoras, M;
Bjørås, Magnar;
Aas, PA;
Sundheim, Ottar;
Seeberg, E.
(2004)
Substrate specificities of bacterial and human AlkB proteins.
Nucleic Acids Research (NAR)
Academic article
-
Alseth, Ingrun;
Korvald, Hanne;
Osman, F.;
Seeberg, Erling Christen;
Bjørås, Magnar.
(2004)
A general role of the DNA glycosylase Nth1 in the abasic sites cleavage step of base excision repair in Schizosaccharomyces pombe.
Nucleic Acids Research (NAR)
Academic article
-
Aamodt, Randi;
Falnes, Pål;
Johansen, RF;
Seeberg, Erling Christen;
Bjørås, Magnar.
(2004)
The Bacillus subtilis counterpart of the mammalian 3-methyladenine DNA glycosylase has hypoxanthine and 1,N-6-ethenoadenine as preferred substrates.
Journal of Biological Chemistry
Academic article
-
Aas, Per Arne;
Otterlei, Marit;
Falnes, P.Ø;
Vågbø, Cathrine;
Skorpen, Frank;
Akbari, Mansour.
(2003)
Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA.
Nature
Academic article
-
Olsen, Ann-Karin;
Duale, Nur;
Bjørås, Magnar;
Larsen, Cathrine T.;
Wiger, Richard;
Holme, Jørn A..
(2003)
Limited repair of 8-hydroxy-7,8-dihydroguanine residues in human testicular cells.
Nucleic Acids Research (NAR)
Academic article
-
Olsen, Ann-Karin Hardie;
Bjørntuft, Helle;
Wiger, Richard;
Holme, Jørn A.;
Seeberg, Erling Christen;
Bjørås, Magnar.
(2001)
Highly efficient Base Excision Repair (BER) in human and rat male germ cells.
Nucleic Acids Research (NAR)
Academic article
-
Holme, Jørn A.;
Bjørge, Christine;
Trbojevic, M.;
Olsen, Ann-Karin;
Brunborg, Gunnar;
Søderlund, Erik Johan.
(1998)
Effects of chemical-induced DNA damage on male germ cells.
Archives of Toxicology
Academic article
Part of book/report
-
Seeberg, Trine Margrethe;
Austad, Hanne Opsahl;
Clausen, Ingelin;
Cederkvist, Fritjof Henning;
Bjørås, Magnar;
Johansen, Rune Forstrøm.
(2015)
An in vitro study of Protein Adsorption to Biocompatible Coatings.
IOS Press
Academic chapter/article/Conference paper
Report
-
Grønland, Mari Therese;
Eijsink, Vincent;
Dalhus, Bjørn;
Bjørås, Magnar;
Carlson, Cathrine Rein.
(2015)
Human CaMKIId mutanter – proteinekspresjon, rensing, krystallisering og analyse av SN-peptid binding.
NMBU,IKBM
Masters thesis
-
Sneve, Ragnhild;
Bjørås, Magnar.
(2010)
Microbial RNomics and the role of small transmembrane peptides in genotoxic stress control.
Unipub forlag
Series of dissertations submitted to the Faculty of Medicine, University of Oslo (1051)
Doctoral dissertation
-
Rolseth, Veslemøy;
Bjørås, Magnar.
(2007)
DNA glycosylases initiating repair of oxidative DNA lesions in mammalian cells.
Unipub forlag
Dissertation for the degree of Dr.Med. (541)
Doctoral dissertation
Outreach
2024
-
PosterEgiazarian, Milena Armenovna; Abentung, Andreas; Karabeika, Emily; Hanumaihgari, Priyanka; Schnur, Paulina; Hovland, Oline Øie. (2024) The role of impaired oxidative base lesion repair in Alzheimer's disease . Alzheimer's Association International Conference 2024-07-28 - 2024-08-01
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PosterBali, Nesrine; Kissova, Miroslava; Bjørås, Magnar; Bandyopadhyay, Sulalit. (2024) Kinetically Controlled Loading of Hydrophilic Iron Oxide Nanoclusters in Hydrophobic Polymeric Nanoparticles through Flash Nanoprecipitation . NanoBioTech-Montreux Conference 2024 , Montreux 2024-11-11 - 2024-11-13
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PosterBali, Nesrine; Kissova, Miroslava; Bjørås, Magnar; Bandyopadhyay, Sulalit. (2024) Kinetically Controlled Loading of Hydrophilic Iron Oxide Nanoclusters in Hydrophobic Polymeric Nanoparticles through Flash Nanoprecipitation. Particle Engineering Days 2024 - 4th Annual Meeting , Trondheim 2024-12-09 - 2024-12-10
2023
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Academic lectureBali, Nesrine; Brennhaug, Svein Jonsson; Bjørås, Magnar; Manaf, Adeel; Bandyopadhyay, Sulalit. (2023) Design of Polymeric Magnetic Nanoparticles for Biomedical Applications. Particle Engineering Centre Particle Engineering Annual Meeting 2023 , Trondheim 2023-12-04 - 2023-12-05
2022
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PosterBali, Nesrine; Manaf, Adeel; Brennhaug, Svein Jonsson; Bjørås, Magnar; Bandyopadhyay, Sulalit. (2022) Optimization of Carboxyl-Coated Magnetic Nanoparticles for DNA Size Selection. First TNNN Conference 2022-11-30 - 2022-12-01
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PosterAli, Zeeshan; Ravlo, Erlend; Aas, Per Arne; Hagen, Lars; Erlandsen, Sten Even; Ottesen, Vegar. (2022) Scalable Production of Silica-coated Magnetic Nanobeads and their Applications in Viral Diagnostics. European Colloid & Interface Society 36th European Colloid & Interface Society Conference , Chania, Crete 2022-09-04 - 2022-09-09
2020
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InterviewBandyopadhyay, Sulalit; Bjørås, Magnar; Steigedal, Tonje S.. (2020) COVID-19 Diagnostic: From Small Scale to Production in a Few Weeks. NKS Kjemi NKS Kjemi [Journal] 2020-06-01
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Academic lectureXu, Kaiqi; Chatzitakis, Athanasios Eleftherios; Backe, Paul Hoff; Ruan, Qiushi; Tang, Junwang; Bjørås, Magnar. (2020) The use of NMR to assess the activity of formate dehydrogenase biocatalysts for CO2 utilization. MR2020 2020-01-07 - 2020-01-08
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InterviewBandyopadhyay, Sulalit; Bjørås, Magnar; Steigedal, Tonje S.. (2020) COVID-19 Diagnostic: From Small Scale to Production in a Few Weeks. NBS-nytt 2-2020 NBS-nytt 2-2020 [Journal] 2020-06-01
2019
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Academic lectureBösl, Korbinian; Ianevski, Aleksandr; Than, Thoa T.; Andersen, Petter I.; Teppor, Mona; Zusinaite, Eva. (2019) Critical Nodes of Viral Modulation Revealed Through an Integrated Network Analysis of Host-Virus Interaction Landscape. Norwegian Biochemical Society Norwegian Biochemical Society 55th Contact Meeting , Røros 2019-01-24 - 2019-01-27
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Academic lectureBösl, Korbinian; Ianevski, Aleksandr; Than, Thoa T.; Andersen, Petter I.; Kuivanen, Suvi; Mona, Teppor. (2019) Critical Nodes of Virus–Host Interaction Revealed Through an Integrated Network Analysis. International Conference on Molecular Mechanisms of Inflammation , Trondheim 2019-06-03 - 2019-06-06
2018
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PosterLiu, Xin; Chatzitakis, Athanasios Eleftherios; Almeida Carvalho, Patricia; Backe, Paul Hoff; Yang, Mingyi; Bjørås, Magnar. (2018) Enzyme-assisted Catalysis on Black Titania Electrodes. The national meeting of the Norwegian Chemical Society , Lillestrøm 2018-10-16 - 2018-10-18
2017
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PosterYang, Juan; Mei, Sen; Grandcolas, Mathieu; Simon, Christian; Xu, Kaiqi; Chatzitakis, Athanasios Eleftherios. (2017) Synthesis of Nanosized Cobalt Oxides and Application in a Bio-hybrid Photoelectrochemical Cell for CO2 Utilization. the 2nd biannual International Solar Fuels conference , San Diego 2017-07-06 - 2017-07-12
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Academic lectureAndersson, Krister; Morland, Cecilie; Haugen, Øyvind Pernell; Hadzic, Alena; Kleppa, Liv; Gille, Andreas. (2017) Exercise benefits brain through the lactate receptor HCAR1, increasing VEGF and capillary density in hippocampus and cortex. The Lundbeck Foundation, Danish Univs & Danish Soc Neurosci The Brain Prize Meeting 2017 , Hindsgavl Castle, Middelfart 2017-10-30 - 2017-11-01
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Academic lectureEnciso, JM; Gutzkow, Kristine Bjerve; Olsen, Ann-Karin; Bjørås, Magnar; Forstrøm, Rune Johansen; Brunborg, Gunnar. (2017) Increasing the sensitivity of the alkaline comet assay by detection of DNA lesions using different human and bacterial repair enzymes. The 12th International Conference and 5th Asian Congress on Environmental Mutagens (ICEM-ACEM 2017) , Incheon 2017-11-12 - 2017-11-16
2016
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Academic lectureNilsen, Hilde; Kroustallaki, Pinelopi; Alsøe, Lene; Huroz, Sergio C; Sarno, Antonio; Esbensen, Ying. (2016) Telomere maintenance defects in mice deficient in SMUG1 uracil-DNA glycosylase. 10th 3R International Symposium Organizing Committee 10th 3R International Symposium , Matsue 2016-11-13 - 2016-11-17
2015
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Academic lectureBjørås, Magnar. (2015) Impact of oxidative DNA base lesion repair on brain function. Zing Conferences Zing conference on genome integrity , Cairns 2015-08-01 - 2015-08-05
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PosterYtre-Arne, Mari; Cornaciu, Irina; Hoffmann, Guillaume; Zander, Ulrich; Rodriguez-Puente, Sonia; Mariaule, Vincent. (2015) Inhibitors of DNA glycosylases as adjuvants in cancer treatment ~New tools for ligand screening ~ . The Norwegian Synchrotron- and Neutron User Meeting 2015 2015-01-19 - 2015-01-20
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Academic lectureYtre-Arne, Mari; Underhaug, Jarl; Cornaciu, Irina; Hoffmann, Guillaume; Martinez, Aurora; Bowler, Matthew. (2015) Experimental structures of human 8-oxoguanine glycosylase 1 in complex with novel inhibitors. NBS Norsk Biokjemisk Selskap Kontaktmøte 2015 , Longyearbyen, Svalbard 2015-02-13 - 2015-02-17
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PosterDalhus, Bjørn; Backe, Paul Hoff; Lærdahl, Jon Kristen; Rowe, Alexander D.; Blicher, Pernille; Forstrøm, Rune Johansen. (2015) Helse Sør-Øst Core Facility for Structural Biology and Bioinformatics. NBS Norsk Biokjemisk Selskap Kontaktmøte 2015 , Longyearbyen, Svalbard 2015-02-13 - 2015-02-17
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Academic lectureBacke, Paul Hoff; Kittelsen, Lene Svendsen; Elgstøen, Katja B. Prestø; Mørkrid, Lars; Bjørås, Magnar. (2015) Functional and structural characterization of the human phosphohexomutases PGM1 and PGM3. NBS NBS Contact Meeting 2015 , Svalbard 2015-02-09 - 2015-02-13
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Academic lectureOttesen, Anett Hellebø; Carlson, Cathrine Rein; Louch, William Edward; Dahl, Mai Britt; Sandbu, Ragnhild Askeland; Johansen, Rune F.. (2015) Enhanced myocardial chromogranin A glycosylation in acute heart failure: reduced processing and potential impact on cardiomyocyte calcium homeostasis. American Heart Association AHA Scientific Session , Florida 2015-11-07 - 2015-11-11
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Academic lectureOttesen, Anett Hellebø; Carlson, Cathrine Rein; Louch, William Edward; Johansen, Rune F.; Stridsberg, Mats; Jarstadmarken, Hilde. (2015) Chromogranin A is a potent prognostic biomarker in acute heart failure, and its fragment catestatin regulates cardiomyocyte calcium homeostasis by CaMKII inhibition. American Heart Association BCVS 2015 Conference , New Orleans 2015-07-13 - 2015-07-16
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Academic lectureSeeberg, Trine Margrethe; Austad, Hanne Opsahl; Clausen, Ingelin; Cederkvist, Fritjof Henning; Bjørås, Magnar; Johansen, Rune Forstrøm. (2015) An in vitro study of Protein Adsorption to Biocompatible Coatings. pHealth 2015 2015-06-02 - 2015-06-04
2014
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PosterAndersen, Pernille Strøm; Backe, Paul Hoff; Lærdahl, Jon Kristen; Rowe, Alexander; Forstrøm, Rune Johansen; Rognes, Torbjørn. (2014) Helse Sør-Øst Core Facility for Structural Biology and Bioinformatics. Norsk Biokjemisk Selskap NBS Contact meeting 2014 , Røros 2014-02-23 - 2014-02-26
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PosterYtre-Arne, Mari; Suganthan, Rajikala; Røhr, Åsmund Kjendseth; Bjørås, Magnar; Dalhus, Bjørn. (2014) Inhibitors of human glycosylases as possible adjuvants in cancer treatment. Norskj Biokjemisk Selskap NBS contact Meeting , Røros 2014-02-23 - 2014-02-26
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Academic lectureDalhus, Bjørn; Vik, Erik Sebastian; Rosnes, Ida; Nawaz, Meh Sameen; Fladeby, Cathrine; Tainer, John A. (2014) DNA AND RNA SUBSTRATE PREFERENCES OF ENDONUCLEASE V – IMPLICATIONS FOR THE BIOLOGICAL ROLE. Dynamic Structures in DNA Damage Responses and Cancer Conference , Cancun 2014-02-12 - 2014-02-15
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PosterYtre-Arne, Mari; Suganthan, Rajikala; Røhr, Åsmund Kjendseth; Bjørås, Magnar; Dalhus, Bjørn. (2014) Virtual docking and TSA screening of a fragment library to identify inhibitors for human DNA glycosylases - possible adjuvants in cancer therapy. International School of Crystallography Structural Basis of Pharmacology - Deeper Understanding of Drug Discovery through Crystallography , Erice 2014-05-30 - 2014-06-08
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PosterBacke, Paul Hoff; Elgstøen, Katja B. Prestø; Bjørås, Magnar; Mørkrid, Lars. (2014) Measuring catalytic activity for wild type and mutant PGM3 by monitoring consumption or production of GlcNAc-6-P using mass spectrometry. SOCIETY FOR THE STUDY OF INBORN ERRORS OF METABOLISM Annual Symposium of the Society for the Study of Inborn Errors of Metabolism , Innsbruck 2014-09-02 - 2014-09-05
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Academic lectureStray-Pedersen, Asbjørg; Backe, Paul Hoff; Sorte, Hanne Sørmo; Mørkrid, Lars; Chokshi, N.Y.; Erichsen, Hans Christian. (2014) A congenital disorder of glycosylation, with lymphopenia, neutropenia, and skeletal dysplasia, caused by mutations in the gene encoding phosphoglucomutase 3 (PGM3). European Society of Human Genetics European Human Genetics Conference , Milano 2014-05-31 - 2014-06-03
2013
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Academic lectureOttesen, Anett Hellebø; Louch, William Edward; Carlson, Cathrine Rein; Landsverk, Ole J. B.; Johansen, Rune Forstrom; Moe, Morten. (2013) 32. Secretoneurin is a novel endogenous CaMKII inhibitor that regulates cardiomyocyte calcium handling and is closely associated with mortality in patients with acute heart failure. Center for Heart Failure Research 11th Annual CHFR Symposium , Oslo 2013-09-19 - 2013-09-20
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Academic lectureOttesen, Anett Hellebø; Louch, William Edward; Carlson, Cathrine Rein; Landsverk, Ole J. B.; Johansen, Rune forstrom; Moe, Morten Carsten. (2013) Secretoneurin regulates cardiomyocyte calcium homeostasis via CaMKIIinhibition and is a potent marker of mortality in patients with acute heart failure. European Society of Cardiology Basic Science Summer School, European Society of Cardiology , Sophia Antipolis 2013-06-16 - 2013-06-20
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PosterRognlien, Anne Gro Wesenberg; Wollen, Embjørg Julianne; Atneosen-Åsegg, Monica; Bjørås, Magnar; Saugstad, Ola Didrik. (2013) Gene expression changes in the brain of Ogg1/Mutyh knockout mice following a hypoxia-reoxygenation insult. ESPR European Society for Pediatric Research anual meeting 2013 , Porto 2013-10-10 - 2013-10-14
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PosterVaaje-Kolstad, Gustav; Bøhle, Liv Anette; Gåseidnes, Sigrid; Dalhus, Bjørn; Bjørås, Magnar; Mathiesen, Geir. (2013) Structural and functional analysis of the Enterococcus faecalis CBM33-type LPMO. 10th Carbohydrate Bioengineering Meeting , Praha 2013-04-21 - 2013-04-24
2012
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PosterBøhle, Liv Anette; Westereng, Bjørge; Dalhus, Bjørn; Bjørås, Magnar; Vaaje-Kolstad, Gustav; Mathiesen, Geir. (2012) The chitinolytic machinery of Enterococcus faecalis V583 includes an enzymatically active CBM33 that promotes polysaccharide degradation using a novel mechanism. The Norwegian Biochemical Society The Norwegian Biochemical Society 48th contact meeting , Storefjell 2012-01-19 - 2012-01-22
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PosterBøhle, Liv Anette; Westereng, Bjørge; Dalhus, Bjørn; Bjørås, Magnar; Aam, Berit Bjugan; Vaaje-Kolstad, Gustav. (2012) The chitinolytic machinery of Enterococcus faecalis v583 includes an enzymatically active CBM33 that promotes polysaccharide degradation using a novel oxidative mechanism. 12th International Conference on Chitin and Chitosan , Fortaleza 2012-09-02 - 2012-09-05
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PosterBøhle, Liv Anette; Gåseidnes, Sigrid; Westereng, Bjørge; Dalhus, Bjørn; Bjørås, Magnar; Mathiesen, Geir. (2012) Structural and functional characterization of the Enterococcus faecalis CBM33 lytic polysaccharide monooxygenase. PolyRefNorth – network 2nd Annual Seminar “Refining Lignocellulosics to Advanced Polymers and Fibers" , Stockholm 2012-10-24 - 2012-10-25
2011
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Academic lectureFinsen, Alexandra; Hildestrand, Gunn Annette; Sjaastad, Ivar; Vinge, Leif Erik; Louch, William Edward; Sandanger, Øystein. (2011) The DNA glycosylase Neil3 regulates stem cell recruitment, cell proliferation and DNA repair following myocardial infaction. Center for Heart Failure Research 9th Annual CHFR Symposium , Oslo 2011-09-15 - 2011-09-16
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PosterBøhle, Liv Anette; Westereng, Bjørge; Dalhus, Bjørn; Bjørås, Magnar; Forsberg, Zarah; Horn, Svein Jarle. (2011) The chitinolytic machinery of Enterococcus faecalis V583 includes an enzymatically active CBM33 that promotes polysaccharide degradation using a novel oxidative mechanism. 10th Symposium on Lactic Acid Bacteria, Egmond aan Zee, the Netherlands 2011-08-28 - 2011-09-01
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Academic lectureWanichawan, Pimthanya; Lunde, Ida Gjervold; Aronsen, Jan Magnus; Cederkvist, Fritjof Henning; Austbø, Bjørg; Lunde, Marianne. (2011) Increased calpain-mediated cleavage of the cardiac Na+- Ca2+ exchanger 1 (NCX1) in the heart failure. International Scientific Committee Na/Ca-exchange 6th International Conference on Na/Ca-exchange 2011 , Ischia Island 2011-10-01 - 2011-10-05
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Academic lectureWanichawan, Pimthanya; Lunde, Ida Gjervold; Aronsen, Jan Magnus; Cederkvist, Fritjof Henning; Austbø, Bjørg; Lunde, Marianne. (2011) Increased calpain-mediated cleavage of the cardiac Na+-Ca2+ exchanger 1 (NCX1) in the heart failure. CHFR