Magne Børset
About
Mini-CV
- M.D. 1988
- Ph.D. 1996
- Specialist in clinical immunology and transfusion medicine
Current positions
- Professor of cell biology and hematological cancer, NTNU
- Senior Consultant, Dept. of Immunology and Transfusion Medicine, St. Olavs Hospital
Research highlights in the study of multiple myeloma (MM):
- 1993: Description of a new separation method for MM cells based on antibodies against syndecan-1 (CD138).
- 1994: Establishment of OH-2, an IL-6- and TNF-dependent MM cell line that has since been shown to be a unique hyperdiploid cell line without IgH translocations.
- 1996: The first publication ever on NF-kappa-B activation in human MM cells
- 1996: First publications on expression of hepatocyte growth factor (HGF) and autocrine stimulation of the HGF receptor c-Met in MM cells.
- 1996: Elevation of HGF in serum from patients with MM compared to healthy controls
- 1998: Serum HGF concentration is a prognostic factor for patients with MM and is reduced after response to treatment.
- 1999: Description of a dual role of Fas in myeloma cells; induction of both apoptosis and proliferative responses.
- 1999: HGF induces production of the osteoclast-stimulating cytokine IL-11 in osteoblastic cells.
- 1999: First paper showing proliferation of myeloma cells induced by IL-15 and production of IL-15 mRNA in MM cells.
- 1999: Establishment of a mouse model for MM showing depletion of osteoblasts from affected skeletal tissue.
- 2000: First paper on prognostic impact of serum level of syndecan-1 in patients with MM
- 2000: Polarization of syndecan-1 and heparin-binding molecules on the surface of MM cells
- 2000: High levels of syndecan-1 in MM bone marrow modulate the activity of HGF.
- 2000: First paper on expression of urokinase plasminogen activator (uPA) and the aPA receptor in MM cells.
- 2001: Bone morphogenetic protein-4 (BMP-4) induces apoptosis in MM cells.
- 2001: First paper showing reduced levels of osteoprotegerin (OPG) in serum from patients with MM
- 2002: First paper on proliferative effect of IL-21 on MM cells.
- 2002: Serum IGF-1 is not elevated in MM patients, but is still a prognostic factor
- 2002: OPG is bound and internalized by MM cells.
- 2004: BMP-5, -6 and -7 induce apoptosis in MM cells.
- 2004: Osteopontin is an adhesive factor for MM cells and is increased in serum from patients with MM
- 2005: An inhibitor of HGF receptor c-Met blocks autocrine growth of MM cells.
- 2005: HGF induces adhesion of MM cells to fibronectin
- 2006: First paper showing that toll-like receptors mediate proliferation of MM cells.
- 2007: HGF inhibits BMP-induced osteoclastogensis.
- 2008: Metastasis-associated phosphatase PRL-3 is expressed in malignant but not in healthy plasma cells.
- 2008: HGF promotes migration of MM cells
- 2008: Elevated serum levels of HGF activator in patients with MM
- 2010: Myeloma cell line OH-2 is hyperdiploid and represents a subgroup of myeloma cases that are frequent but rarely give rise to cell lines.
- 2011: The kinase SGK-1 is expressed in myeloma cells where it promotes cell growth.
- 2012: BMPs induce apoptosis of myeloma cells by repressing MYC.
- 2013: Anti-c-Met nanobodies as potential myeloma drug.
- 2013: Synergy between HGF, IGF-1 and SGK-1 in promoting myeloma cell growth.
- 2016: PRL-3 is important for IL-6-mediated survival of myeloma cells.
- 2017: Src Family Kinases Are Regulated in Multiple Myeloma Cells by PRL-3
- 2017: First papers showing that PRL-3 is overexpressed in prostate cancer cells and is associated with an unfavorable prognosis
- 2018: PRL-3 is expressed and is important for migration in B cell lymphoblastic leukemia and Hodgkin lymphoma
- 2020: Myeloma converts ATP to immunosuppressive adenosine by the enzymes CD39 and CD73. Immunosuppression can be reverted by blocking CD39 and adenosine receptors.
- 2021: Inhibitors of PHGDH, an enzyme in the serine synthesis pathway, can induce death of myeloma cells both in vitro and in vivo.
- 2021: PRL-3 stimulates aerobic glycolysis in myeloma cells.
- 2021: PRL-3 acts primarily as a pseudophosphatase.
Publications
2016
-
Våtsveen, Thea Kristin;
Børset, Magne;
Dikic, Aida;
Tian, Erming;
Micci, Francesca;
Lid, Ana Barragan.
(2016)
VOLIN and KJON—Two novel hyperdiploid myeloma cell lines.
Genes, Chromosomes and Cancer
Academic article
-
Abdollahi, Pegah;
Vandsemb, Esten Nymoen;
Hjort, Magnus Aassved;
Misund, Kristine;
Holien, Toril;
Sponaas, Anne-Marit.
(2016)
Src family kinases are regulated in multiple myeloma cells by phosphatase of regenerating liver-3.
Molecular Cancer Research
Academic article
-
Slørdahl, Tobias Schmidt;
Abdollahi, Pegah;
Vandsemb, Esten Nymoen;
Rampa, Christoph Samuel;
Misund, Kristine;
Baranowska, Katarzyna Anna.
(2016)
The phosphatase of regenerating liver-3 (PRL-3) is importantfor IL-6-mediated survival of myeloma cells.
OncoTarget
Academic article
2013
-
Slørdahl, Tobias Schmidt;
Denayer, Tinneke;
Moen, Siv Helen;
Standal, Therese;
Børset, Magne;
Ververken, Cedric.
(2013)
Anti-c-MET Nanobody® – a new potential drug in multiple myeloma treatment.
European Journal of Haematology
Academic article
-
Rø, Torstein Baade;
Holien, Toril;
Fagerli, Unn-Merete;
Hov, Håkon;
Misund, Kristine;
Waage, Anders.
(2013)
HGF and IGF-1 synergize with SDF-1α in promoting migration of myeloma cells by cooperative activation of p21-activated kinase.
Experimental Hematology
Academic article
2012
-
Holien, Toril;
Våtsveen, Thea Kristin;
Hella, Hanne;
Rampa, Christoph Samuel;
Brede, Gaute;
Grøseth, Lill Anny Gunnes.
(2012)
Bone morphogenetic proteins induce apoptosis in multiple myeloma cells by Smad-dependent repression of MYC.
Leukemia
Academic article
-
Wader, Karin Fahl;
Fagerli, Unn-Merete;
Børset, Magne;
Lydersen, Stian;
Hov, Håkon;
Sundan, Anders.
(2012)
Immunohistochemical analysis of hepatocyte growth factor and c-Met in plasma cell disease.
Histopathology
Academic article
2011
-
Skliris, A;
Happonen, KE;
Terpos, Evangelos;
Labropoulou, V;
Børset, Magne;
Heinegård, Dick.
(2011)
Serglycin inhibits the classical and lectin pathways of complement via its glycosaminoglycan chains: Implications for multiple myeloma.
European Journal of Immunology
Academic article
-
Wader, Karin Fahl;
Fagerli, Unn-Merete;
Holt, Randi Utne;
Børset, Magne;
Sundan, Anders;
Waage, Anders.
(2011)
Soluble c-Met in serum of patients with multiple myeloma: correlation with clinical parameters.
European Journal of Haematology
Academic article
-
Fagerli, Unn-Merete;
Ullrich, K;
Stühmer, Thorsten;
Holien, Toril;
Köchert, K;
Holt, Randi Utne.
(2011)
Serum/glucocorticoid-regulated kinase 1 (SGK1) is a prominent target gene of the transcriptional response to cytokines in multiple myeloma and supports the growth of myeloma cells.
Oncogene
Academic article
2009
-
Vatsveen, TK;
Våtsveen, Thea Kristin;
Tian, Erming;
Kresse, Stine H;
Meza-Zepada, Leonardo;
Meza, Leonardo Zepeda.
(2009)
OH-2, a hyperdiploid myeloma cell line without an IGH translocation, has a complex translocation juxtaposing MYC near MAFB and the IGK locus.
Leukemia Research
Academic article
-
Våtsveen, Thea Kristin;
Brenne, Anne-Tove;
Dai, HY;
Waage, Anders;
Sundan, Anders;
Børset, Magne.
(2009)
FGFR3 is expressed and is important for survival in INA-6, a human myeloma cell line without a t(4;14).
European Journal of Haematology
Academic article
2008
-
Fagerli, Unn-Merete;
Holt, Randi Utne;
Holien, Toril;
Våtsveen, Thea Kristin;
Zhan, FH;
Egeberg, Kjartan Wøllo.
(2008)
Overexpression and involvement in migration by the metastasis-associated phosphatase PRL-3 in human myeloma cells.
Blood
Academic literature review
2007
-
Holt, RU;
Fagerli, UM;
Ro, TB;
Baykov, V;
Waage, Anders;
Sundan, Anders.
(2007)
HGF promotes migration of myeloma cells.
Haematologica
Abstract
2006
-
Standal, Therese;
Abildgaard, Niels;
Fagerli, Unn-merete;
Størdal, Berit Fladvad;
Hjertner, Øyvind;
Børset, Magne.
(2006)
HGF Inhibits BMP-Induced Osteoblastogenesis: Implications for the Bone Disease in Multiple Myeloma.
Blood
Abstract
-
Bohnhorst, Janne Øvrebø;
Rasmussen, T;
Moen, Siv H;
Fløttum, Marianne;
Knudsen, L;
Børset, Magne.
(2006)
Toll-like receptors mediate proliferation and survival of multiple myeloma cells.
Leukemia
Academic article
2005
-
Holt, Randi Utne;
Baykov, Vadim;
Rø, Torstein Baade;
Brabrand, Sigmund;
Waage, Anders;
Sundan, Anders.
(2005)
Human myeloma cells adhere to fibronectin in response to hepatocyte growth factor.
Haematologica
Academic article
2004
-
Hov, Håkon;
Holt, Randi Utne;
Rø, Torstein Baade;
Fagerli, Unn-Merete;
Hjort-Hansen, Henrik;
Baykov, Vadim.
(2004)
A Selective c-Met Inhibitor Blocks an Autocrine Hepatocyte Growth Factor Growth Loop in ANBL-6 Cells and Prevents Migration and Adhesion of Myeloma cells.
Clinical Cancer Research
Academic article
-
Holt, Randi Utne;
Hjorth-Hansen, Henrik;
Waage, Anders;
Hjertner, ¯yvind;
Sundan, Anders;
Børset, Magne.
(2004)
Bone morphogenetic protein-5, -6 and -7 inhibit growth and induce apoptosis in human myeloma cells.
Oncogene
Academic article
2002
-
Standal, Therese;
Børset, Magne;
Lenhoff, S.;
Wisløff, Finn;
Størdal, Berit Fladval;
Sundan, Anders.
(2002)
Serum insulin-like growth factor is not increased in patients with multiple myelomna but is still a prognostic factor.
Blood
Academic article
-
Brenne, Anne Tove;
Rø, Torstein Baade;
Waage, Anders;
Sundan, Anders;
Børset, Magne;
Hjorth-Hansen, Henrik.
(2002)
Interleukin-21 is a growth and survival factor for human myeloma cells.
Blood
Academic article
2001
-
Seidel, Carina;
Hjertner, ¯yvind;
Abildgaard, Niels;
Heikendorff, Lene;
Hjorth, M.;
Westin, Jan.
(2001)
Serum osteoprotegerin levels are reduced in patients with multiple myeloma with lytic bone disease.
Blood
Academic article
-
Hjertner, ¯yvind;
Hjorth-Hansen, Henrik;
Børset, Magne;
Seidel, Carina;
Waage, Anders;
Sundan, Anders.
(2001)
Bone morphogenetic protein-4 inhibits proliferation and induces apoptosis of multiple myeloma cells.
Blood
Academic article
-
Feuerherm, Astrid;
Børset, Magne;
Seidel, Carina;
Sundan, Anders;
Leistad, Lilian;
Østensen, Monica.
(2001)
Elevated levels of osteoprotegerin (OPG) and hepatocyte growth factor (HGF) in rheumatoid arthritis.
Scandinavian Journal of Rheumatology
Academic article
2000
-
Børset, Magne;
Hjertner, ¯yvind;
Yaccoby, Shmuel;
Epstein, Joshua;
Sanderson, Ralph D..
(2000)
Syndecan-1 is targeted to the uropods of polarized myeloma cells where it promotes adhesion and sequesters heparing-binding proteins.
Blood
Academic article
-
Seidel, Carina;
Børset, Magne;
Hjertner, ¯yvind;
Cao, Dianjun;
Abildgaard, Niels;
Hjorth-Hansen, Henrik.
(2000)
High levels of soluble syndecan-1 in myeloma-derived bone marrow : modulation of hepatocyte growth factor activity.
Blood
Academic article
-
Seidel, Carina;
Sundan, Anders;
Hjorth, Martin;
Turesson, Ingemar;
Dahl, Inger Marie S.;
Abildgaard, Niels.
(2000)
Serum syndecan-1: a new independent prognostic marker in multiple myeloma.
Blood
Academic article
1999
-
Børset, Magne;
Hjort-Hansen, Henrik;
Johnsen, Ann-Charlotte;
Seidel, Carina;
Waage, Anders;
Espevik, Terje.
(1999)
Apoptosis, proliferation and NF-k(kappa)B activation induced by agonistic Fas antibodies in the human myeloma cell line OH-2: amplification of Fas-mediated apoptosis by tumor necrosis factor.
European Journal of Haematology
Academic article
-
Hjertner, ¯yvind;
Torgersen, Maria Lyngaas;
Seidel, Carina;
Hjort-Hansen, Henrik;
Waage, Anders;
Børset, Magne.
(1999)
Hepatocyte Growth Factor (HGF) Induces Interleukin-11 Sedretion From Osteoblasts: A Possible Role for HGF in Myeloma-Associated Osteolytic Bone Disease.
Blood
Academic article
-
Hjort-Hansen, Henrik;
Waage, Anders;
Børset, M..
(1999)
Interleukin-15 blocks apoptosis and induces proliferation of the human myeloma cell line OH-2 and freshly isolated myeloma cells.
British Journal of Haematology
Academic article
-
Hjorth-Hansen, H.;
Seifert, MF.;
Børset, M.;
Aarset, H.;
Ostlie, A.;
Sundan, A..
(1999)
Marked osteoblastopenia and reduced bone formation in a model of multiple myeloma bone disease in severe combined immunodeficiency mice.
Journal of Bone and Mineral Research
Academic article
1998
-
Seidel, C;
Børset, M;
Turesson, I;
Abilgaard, N;
Sundan, A.;
Waage, Anders.
(1998)
Elevated serum concentrations of hepatocyte growth factor in patients with multiple myeloma. The Nordic Myeloma Study Group.
Blood
Academic article
1996
-
Børset, Magne;
Medvedev, Andrei E.;
Sundan, Anders;
Espevik, Terje.
(1996)
The role of the two TNF receptors in proliferation, NF-_KB activation and discrimination between TNF and LT_a signalling in the human myeloma cell line OH-2.
Cytokine
Academic article
-
Børset, Magne;
Lien, Egil;
Espevik, Terje;
Helseth, Eirik;
Waage, Anders;
Sundan, Anders.
(1996)
Concomitant expression of hepatocyte growth factor/scatter factor and the receptor c-MET in human myeloma cell lines.
Journal of Biological Chemistry
Academic article
-
Børset, Magne;
Hjorth-Hansen, Henrik;
Seidel, Carina;
Sundan, Anders;
Waage, Anders.
(1996)
Hepatocyte growth factor and its receptor c-MET in multiple myeloma.
Blood
Academic article
Journal publications
-
Våtsveen, Thea Kristin;
Børset, Magne;
Dikic, Aida;
Tian, Erming;
Micci, Francesca;
Lid, Ana Barragan.
(2016)
VOLIN and KJON—Two novel hyperdiploid myeloma cell lines.
Genes, Chromosomes and Cancer
Academic article
-
Abdollahi, Pegah;
Vandsemb, Esten Nymoen;
Hjort, Magnus Aassved;
Misund, Kristine;
Holien, Toril;
Sponaas, Anne-Marit.
(2016)
Src family kinases are regulated in multiple myeloma cells by phosphatase of regenerating liver-3.
Molecular Cancer Research
Academic article
-
Slørdahl, Tobias Schmidt;
Abdollahi, Pegah;
Vandsemb, Esten Nymoen;
Rampa, Christoph Samuel;
Misund, Kristine;
Baranowska, Katarzyna Anna.
(2016)
The phosphatase of regenerating liver-3 (PRL-3) is importantfor IL-6-mediated survival of myeloma cells.
OncoTarget
Academic article
-
Slørdahl, Tobias Schmidt;
Denayer, Tinneke;
Moen, Siv Helen;
Standal, Therese;
Børset, Magne;
Ververken, Cedric.
(2013)
Anti-c-MET Nanobody® – a new potential drug in multiple myeloma treatment.
European Journal of Haematology
Academic article
-
Rø, Torstein Baade;
Holien, Toril;
Fagerli, Unn-Merete;
Hov, Håkon;
Misund, Kristine;
Waage, Anders.
(2013)
HGF and IGF-1 synergize with SDF-1α in promoting migration of myeloma cells by cooperative activation of p21-activated kinase.
Experimental Hematology
Academic article
-
Holien, Toril;
Våtsveen, Thea Kristin;
Hella, Hanne;
Rampa, Christoph Samuel;
Brede, Gaute;
Grøseth, Lill Anny Gunnes.
(2012)
Bone morphogenetic proteins induce apoptosis in multiple myeloma cells by Smad-dependent repression of MYC.
Leukemia
Academic article
-
Wader, Karin Fahl;
Fagerli, Unn-Merete;
Børset, Magne;
Lydersen, Stian;
Hov, Håkon;
Sundan, Anders.
(2012)
Immunohistochemical analysis of hepatocyte growth factor and c-Met in plasma cell disease.
Histopathology
Academic article
-
Skliris, A;
Happonen, KE;
Terpos, Evangelos;
Labropoulou, V;
Børset, Magne;
Heinegård, Dick.
(2011)
Serglycin inhibits the classical and lectin pathways of complement via its glycosaminoglycan chains: Implications for multiple myeloma.
European Journal of Immunology
Academic article
-
Wader, Karin Fahl;
Fagerli, Unn-Merete;
Holt, Randi Utne;
Børset, Magne;
Sundan, Anders;
Waage, Anders.
(2011)
Soluble c-Met in serum of patients with multiple myeloma: correlation with clinical parameters.
European Journal of Haematology
Academic article
-
Fagerli, Unn-Merete;
Ullrich, K;
Stühmer, Thorsten;
Holien, Toril;
Köchert, K;
Holt, Randi Utne.
(2011)
Serum/glucocorticoid-regulated kinase 1 (SGK1) is a prominent target gene of the transcriptional response to cytokines in multiple myeloma and supports the growth of myeloma cells.
Oncogene
Academic article
-
Vatsveen, TK;
Våtsveen, Thea Kristin;
Tian, Erming;
Kresse, Stine H;
Meza-Zepada, Leonardo;
Meza, Leonardo Zepeda.
(2009)
OH-2, a hyperdiploid myeloma cell line without an IGH translocation, has a complex translocation juxtaposing MYC near MAFB and the IGK locus.
Leukemia Research
Academic article
-
Våtsveen, Thea Kristin;
Brenne, Anne-Tove;
Dai, HY;
Waage, Anders;
Sundan, Anders;
Børset, Magne.
(2009)
FGFR3 is expressed and is important for survival in INA-6, a human myeloma cell line without a t(4;14).
European Journal of Haematology
Academic article
-
Fagerli, Unn-Merete;
Holt, Randi Utne;
Holien, Toril;
Våtsveen, Thea Kristin;
Zhan, FH;
Egeberg, Kjartan Wøllo.
(2008)
Overexpression and involvement in migration by the metastasis-associated phosphatase PRL-3 in human myeloma cells.
Blood
Academic literature review
-
Holt, RU;
Fagerli, UM;
Ro, TB;
Baykov, V;
Waage, Anders;
Sundan, Anders.
(2007)
HGF promotes migration of myeloma cells.
Haematologica
Abstract
-
Standal, Therese;
Abildgaard, Niels;
Fagerli, Unn-merete;
Størdal, Berit Fladvad;
Hjertner, Øyvind;
Børset, Magne.
(2006)
HGF Inhibits BMP-Induced Osteoblastogenesis: Implications for the Bone Disease in Multiple Myeloma.
Blood
Abstract
-
Bohnhorst, Janne Øvrebø;
Rasmussen, T;
Moen, Siv H;
Fløttum, Marianne;
Knudsen, L;
Børset, Magne.
(2006)
Toll-like receptors mediate proliferation and survival of multiple myeloma cells.
Leukemia
Academic article
-
Holt, Randi Utne;
Baykov, Vadim;
Rø, Torstein Baade;
Brabrand, Sigmund;
Waage, Anders;
Sundan, Anders.
(2005)
Human myeloma cells adhere to fibronectin in response to hepatocyte growth factor.
Haematologica
Academic article
-
Hov, Håkon;
Holt, Randi Utne;
Rø, Torstein Baade;
Fagerli, Unn-Merete;
Hjort-Hansen, Henrik;
Baykov, Vadim.
(2004)
A Selective c-Met Inhibitor Blocks an Autocrine Hepatocyte Growth Factor Growth Loop in ANBL-6 Cells and Prevents Migration and Adhesion of Myeloma cells.
Clinical Cancer Research
Academic article
-
Holt, Randi Utne;
Hjorth-Hansen, Henrik;
Waage, Anders;
Hjertner, ¯yvind;
Sundan, Anders;
Børset, Magne.
(2004)
Bone morphogenetic protein-5, -6 and -7 inhibit growth and induce apoptosis in human myeloma cells.
Oncogene
Academic article
-
Standal, Therese;
Børset, Magne;
Lenhoff, S.;
Wisløff, Finn;
Størdal, Berit Fladval;
Sundan, Anders.
(2002)
Serum insulin-like growth factor is not increased in patients with multiple myelomna but is still a prognostic factor.
Blood
Academic article
-
Brenne, Anne Tove;
Rø, Torstein Baade;
Waage, Anders;
Sundan, Anders;
Børset, Magne;
Hjorth-Hansen, Henrik.
(2002)
Interleukin-21 is a growth and survival factor for human myeloma cells.
Blood
Academic article
-
Seidel, Carina;
Hjertner, ¯yvind;
Abildgaard, Niels;
Heikendorff, Lene;
Hjorth, M.;
Westin, Jan.
(2001)
Serum osteoprotegerin levels are reduced in patients with multiple myeloma with lytic bone disease.
Blood
Academic article
-
Hjertner, ¯yvind;
Hjorth-Hansen, Henrik;
Børset, Magne;
Seidel, Carina;
Waage, Anders;
Sundan, Anders.
(2001)
Bone morphogenetic protein-4 inhibits proliferation and induces apoptosis of multiple myeloma cells.
Blood
Academic article
-
Feuerherm, Astrid;
Børset, Magne;
Seidel, Carina;
Sundan, Anders;
Leistad, Lilian;
Østensen, Monica.
(2001)
Elevated levels of osteoprotegerin (OPG) and hepatocyte growth factor (HGF) in rheumatoid arthritis.
Scandinavian Journal of Rheumatology
Academic article
-
Børset, Magne;
Hjertner, ¯yvind;
Yaccoby, Shmuel;
Epstein, Joshua;
Sanderson, Ralph D..
(2000)
Syndecan-1 is targeted to the uropods of polarized myeloma cells where it promotes adhesion and sequesters heparing-binding proteins.
Blood
Academic article
-
Seidel, Carina;
Børset, Magne;
Hjertner, ¯yvind;
Cao, Dianjun;
Abildgaard, Niels;
Hjorth-Hansen, Henrik.
(2000)
High levels of soluble syndecan-1 in myeloma-derived bone marrow : modulation of hepatocyte growth factor activity.
Blood
Academic article
-
Seidel, Carina;
Sundan, Anders;
Hjorth, Martin;
Turesson, Ingemar;
Dahl, Inger Marie S.;
Abildgaard, Niels.
(2000)
Serum syndecan-1: a new independent prognostic marker in multiple myeloma.
Blood
Academic article
-
Børset, Magne;
Hjort-Hansen, Henrik;
Johnsen, Ann-Charlotte;
Seidel, Carina;
Waage, Anders;
Espevik, Terje.
(1999)
Apoptosis, proliferation and NF-k(kappa)B activation induced by agonistic Fas antibodies in the human myeloma cell line OH-2: amplification of Fas-mediated apoptosis by tumor necrosis factor.
European Journal of Haematology
Academic article
-
Hjertner, ¯yvind;
Torgersen, Maria Lyngaas;
Seidel, Carina;
Hjort-Hansen, Henrik;
Waage, Anders;
Børset, Magne.
(1999)
Hepatocyte Growth Factor (HGF) Induces Interleukin-11 Sedretion From Osteoblasts: A Possible Role for HGF in Myeloma-Associated Osteolytic Bone Disease.
Blood
Academic article
-
Hjort-Hansen, Henrik;
Waage, Anders;
Børset, M..
(1999)
Interleukin-15 blocks apoptosis and induces proliferation of the human myeloma cell line OH-2 and freshly isolated myeloma cells.
British Journal of Haematology
Academic article
-
Hjorth-Hansen, H.;
Seifert, MF.;
Børset, M.;
Aarset, H.;
Ostlie, A.;
Sundan, A..
(1999)
Marked osteoblastopenia and reduced bone formation in a model of multiple myeloma bone disease in severe combined immunodeficiency mice.
Journal of Bone and Mineral Research
Academic article
-
Seidel, C;
Børset, M;
Turesson, I;
Abilgaard, N;
Sundan, A.;
Waage, Anders.
(1998)
Elevated serum concentrations of hepatocyte growth factor in patients with multiple myeloma. The Nordic Myeloma Study Group.
Blood
Academic article
-
Børset, Magne;
Medvedev, Andrei E.;
Sundan, Anders;
Espevik, Terje.
(1996)
The role of the two TNF receptors in proliferation, NF-_KB activation and discrimination between TNF and LT_a signalling in the human myeloma cell line OH-2.
Cytokine
Academic article
-
Børset, Magne;
Lien, Egil;
Espevik, Terje;
Helseth, Eirik;
Waage, Anders;
Sundan, Anders.
(1996)
Concomitant expression of hepatocyte growth factor/scatter factor and the receptor c-MET in human myeloma cell lines.
Journal of Biological Chemistry
Academic article
-
Børset, Magne;
Hjorth-Hansen, Henrik;
Seidel, Carina;
Sundan, Anders;
Waage, Anders.
(1996)
Hepatocyte growth factor and its receptor c-MET in multiple myeloma.
Blood
Academic article