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  1. Employees

Språkvelger

Norsk

Marianne Doré Hansen

Marianne Doré Hansen

Researcher
Department of Clinical and Molecular Medicine
Faculty of Medicine and Health Sciences

marianne.hansen@ntnu.no
+4741283928 Gastrosenteret, 432.03.030, Øya, Prinsesse Kristinas gate 1
Gastroenterology and Inflammation How hepatitis C wages guerrilla warfare
About Publications Teaching Media

About

Current research project: Viruses and gut mucosal innate immune responses in inflammatory bowel diseases.

My research has been focused on molecular signaling mechanism in viral-host interaction with emphasize on inflammation, using hepatitis C virus (HCV), a human oncogenic virus, as a model of infection. My current research focus is on virus and gut mucosal innate immune responses in Inflammatory Bowel Disease (IBD) and how both pathogenic and commensal viruses may play a role in the establishment, exacerbation or remission of IBD.

 

 

Curriculum Vitae

  • Researcher at Department of Clinical and Molecular Medicine, NTNU 2018 – now
  • Visiting scientist at Institut Pasteur, Paris, France, Department of Virology, Hepacivirus and innate immunity, 2015 - 2018
  • Post doctor at Department of Laboratory medicine, Children’s and Women’s Health, NTNU 2015-2018
  • Visiting scientist at Institut Pasteur, Paris, France, Department of Virology, Hepacivirus and innate immunity, 2013
  • PhD in Molecular Medicine in Marit W. Anthonsens lab, Department of Laboratory Medicine, Children’s and Women’s Health, NTNU, 2010-2015
  • Senior Engineer, Department of Biology, NTNU, 2000-2010
  • M.Sc. Biotechnology, University in Tromsø, 1996 – 1999
  • B.Sc. (Chemistry), Sør-Trøndelag University College (HiST), Trondheim (1993 - 1996)

Competencies

  • Cell Biology
  • Confocal microscopy
  • Hepatitis Viruses
  • Immunologic Techniques
  • Live cell imaging
  • Liver Diseases
  • Molecular biology
  • Molecular cell biology
  • Molecular immunology
  • Molecular medicine
  • Molecular virology
  • RNA Virus Infections

Publications

  • Chronological
  • By category
  • See all publications in Cristin

2023

  • Hansen, Marianne Dore. (2023) Inflammatoriske tarmsykdommer og viromet. Bioingeniøren
    Popular scientific article
  • Gopalakrishnan, Shreya; Bakke, Ingunn; Hansen, Marianne Dore; Skovdahl, Helene Kolstad; Granlund, Atle van Beelen; Sandvik, Arne Kristian. (2023) Comprehensive protocols for culturing and molecular biological analysis of IBD patient-derived colon epithelial organoids. Frontiers in Immunology
    Academic article

2022

  • Gopalakrishnan, Shreya; Hansen, Marianne Dore; Skovdahl, Helene Kolstad; Roseth, Ingrid Aass; Granlund, Atle van Beelen; Østvik, Ann Elisabet. (2022) Tofacitinib Downregulates TNF and Poly(I:C)-Dependent MHC-II Expression in the Colonic Epithelium. Frontiers in Immunology
    Academic article

2021

  • Bruland, Torunn; Østvik, Ann Elisabet; Sandvik, Arne Kristian; Hansen, Marianne Dore. (2021) Host-Viral Interactions in the Pathogenesis of Ulcerative Colitis. International Journal of Molecular Sciences
    Academic literature review
  • Daussy, Coralie F.; Monard, Sarah C.; Guy, Coralie; Muñoz-González, Sara; Chazal, Maxime; Anthonsen, Marit Walbye. (2021) The inflammasome components NLRP3 and ASC act in concert with IRGM to rearrange the golgi apparatus during hepatitis C virus infection. Journal of Virology
    Academic article

2017

  • Dabo, Stephanie; Maillard, Patrick; Rodriguez, Milagros Collados; Hansen, Marianne Dore; Mazouz, Sabrina; Bigot, Donna-Joe. (2017) Inhibition of the inflammatory response to stress by targeting interaction between PKR and its cellular activator PACT. Scientific Reports
    Academic article
  • Hansen, Marianne Dore; Johnsen, Ingvild Bjellmo; Stiberg, Kim Andre Ha; Sherstova, Tatyana; Wakita, Takaji; Richard, Gabriel Mary. (2017) Hepatitis C virus triggers Golgi fragmentation and autophagy through the immunity-related GTPase M. Proceedings of the National Academy of Sciences of the United States of America
    Academic article
  • Hansen, Marianne Dore. (2017) How hepatitis C wages guerrilla warfare. Gemini.no
    Popular scientific article

2015

  • Hansen, Marianne Dore; Anthonsen, Marit Walbye; Johnsen, Ingvild Bjellmo. (2015) Interplay of single´stranded RNA viruses with autophagy: Intracellular mechanisms and functional impact. NTNU Det medisinske fakultet
    Doctoral dissertation

2014

  • Arukwe, Augustine; Olufsen, Marianne Opsahl; Cicero, Nicola; Hansen, Marianne Dore. (2014) Effects on Development, Growth Responses and Thyroid-Hormone Systems in Eyed-Eggs and Yolk-Sac Larvae of Atlantic Salmon (Salmo salar) Continuously Exposed to 3,3′,4,4′-Tetrachlorobiphenyl (PCB-77). Journal of Toxicology and Environmental Health, Part A
    Academic article

2009

  • Kortner, Trond Moxness; Mortensen, Anne Skjetne; Hansen, Marianne Dore; Arukwe, Augustine. (2009) Neural aromatase transcript and protein levels in Atlantic salmon (Salmo salar) are modulated by the ubiquitous water pollutant, 4-nonylphenol. General and Comparative Endocrinology
    Academic article

2005

  • Akbari, Mansour; Hansen, Marianne Dore; Halgunset, Jostein; Skorpen, Frank; Krokan, Hans Einar. (2005) Low copy number DNA template can render polymerase chain reaction error prone in a sequence-dependent manner. Journal of Molecular Diagnostics
    Academic article

Journal publications

  • Hansen, Marianne Dore. (2023) Inflammatoriske tarmsykdommer og viromet. Bioingeniøren
    Popular scientific article
  • Gopalakrishnan, Shreya; Bakke, Ingunn; Hansen, Marianne Dore; Skovdahl, Helene Kolstad; Granlund, Atle van Beelen; Sandvik, Arne Kristian. (2023) Comprehensive protocols for culturing and molecular biological analysis of IBD patient-derived colon epithelial organoids. Frontiers in Immunology
    Academic article
  • Gopalakrishnan, Shreya; Hansen, Marianne Dore; Skovdahl, Helene Kolstad; Roseth, Ingrid Aass; Granlund, Atle van Beelen; Østvik, Ann Elisabet. (2022) Tofacitinib Downregulates TNF and Poly(I:C)-Dependent MHC-II Expression in the Colonic Epithelium. Frontiers in Immunology
    Academic article
  • Bruland, Torunn; Østvik, Ann Elisabet; Sandvik, Arne Kristian; Hansen, Marianne Dore. (2021) Host-Viral Interactions in the Pathogenesis of Ulcerative Colitis. International Journal of Molecular Sciences
    Academic literature review
  • Daussy, Coralie F.; Monard, Sarah C.; Guy, Coralie; Muñoz-González, Sara; Chazal, Maxime; Anthonsen, Marit Walbye. (2021) The inflammasome components NLRP3 and ASC act in concert with IRGM to rearrange the golgi apparatus during hepatitis C virus infection. Journal of Virology
    Academic article
  • Dabo, Stephanie; Maillard, Patrick; Rodriguez, Milagros Collados; Hansen, Marianne Dore; Mazouz, Sabrina; Bigot, Donna-Joe. (2017) Inhibition of the inflammatory response to stress by targeting interaction between PKR and its cellular activator PACT. Scientific Reports
    Academic article
  • Hansen, Marianne Dore; Johnsen, Ingvild Bjellmo; Stiberg, Kim Andre Ha; Sherstova, Tatyana; Wakita, Takaji; Richard, Gabriel Mary. (2017) Hepatitis C virus triggers Golgi fragmentation and autophagy through the immunity-related GTPase M. Proceedings of the National Academy of Sciences of the United States of America
    Academic article
  • Hansen, Marianne Dore. (2017) How hepatitis C wages guerrilla warfare. Gemini.no
    Popular scientific article
  • Arukwe, Augustine; Olufsen, Marianne Opsahl; Cicero, Nicola; Hansen, Marianne Dore. (2014) Effects on Development, Growth Responses and Thyroid-Hormone Systems in Eyed-Eggs and Yolk-Sac Larvae of Atlantic Salmon (Salmo salar) Continuously Exposed to 3,3′,4,4′-Tetrachlorobiphenyl (PCB-77). Journal of Toxicology and Environmental Health, Part A
    Academic article
  • Kortner, Trond Moxness; Mortensen, Anne Skjetne; Hansen, Marianne Dore; Arukwe, Augustine. (2009) Neural aromatase transcript and protein levels in Atlantic salmon (Salmo salar) are modulated by the ubiquitous water pollutant, 4-nonylphenol. General and Comparative Endocrinology
    Academic article
  • Akbari, Mansour; Hansen, Marianne Dore; Halgunset, Jostein; Skorpen, Frank; Krokan, Hans Einar. (2005) Low copy number DNA template can render polymerase chain reaction error prone in a sequence-dependent manner. Journal of Molecular Diagnostics
    Academic article

Report

  • Hansen, Marianne Dore; Anthonsen, Marit Walbye; Johnsen, Ingvild Bjellmo. (2015) Interplay of single´stranded RNA viruses with autophagy: Intracellular mechanisms and functional impact. NTNU Det medisinske fakultet
    Doctoral dissertation

Teaching

Courses

  • MOL3015 - Nanomedicine 2 - Therapy

Media

2018

  • Academic lecture
    Daussy, Coralie F.; Monard, Sarah C.; Anthonsen, Marit Walbye; Dreux, M; Meurs, Eliane F.; Hansen, Marianne Dore. (2018) HCV infection triggers the IRGM-mediated Golgi fragmentation through the NLRP3 inflammasome. HCV2018 25th International Symposium on Hepatitis C virus and related viruses , Dublin 2018-10-08 - 2018-10-11

2017

  • Academic lecture
    Hansen, Marianne Dore; Johnsen, Ingvild Bjellmo; Stiberg, Kim Andre Ha; Sherstova, Tatyana; Wakita, Takaji; Richard, Gabriel Mary. (2017) Hepatitis C virus triggers Golgi fragmentation and autophagy through the immunity-related GTPase M. CFATG 7th Scientific days on autophagy , Paris 2017-09-28 - 2017-09-29
  • Academic lecture
    Hansen, Marianne Dore. (2017) Hepatitis C virus triggers Golgi fragmentation and autophagy through the immunity-related GTPase M. IKOM Seminar 2017-08-30 -

2016

  • Academic lecture
    Johnsen, Ingvild Bjellmo; Hansen, Marianne Dore; Stiberg, Kim Andre Ha; Tatyana, Sherstova; Mildenberger, Jennifer; Grøvdal, Lene Melsæther. (2016) The innate immune kinase TBK1 controls ULK1 and autophagy induction in response to paramyxovirus infection. CEMIR CEMIR Conference on molecular mechanisms of inflammation , Trondheim 2016-05-30 - 2016-06-02
  • Academic lecture
    Hansen, Marianne Dore. (2016) Hepatitis C virus infection remodels the Golgi complex to trigger autophagy through the immunity-related GTPase M (IRGM). ANRS 16ème réunion du réseau national hépatites , Paris 2016-02-03 - 2016-02-04

2015

  • Academic lecture
    Hansen, Marianne Dore; Johnsen, Ingvild Bjellmo; Stiberg, Kim Andre Ha; Malmo, Jostein; Sherstova, Tatyana; Meurs, Eliane F.. (2015) Hepatitis C virus remodels the Golgi complex to trigger autophagy through the immunity-related GTPase M. Virology Department, Institut Pasteur Annual Virology Department meeting at Institut Pasteur , Pornichet, Bretagne 2015-11-16 - 2015-11-18
  • Interview
    Hansen, Marianne Dore. (2015) Interplay of single-stranded RNA viruses with autophagy. Intracellular mechanisms and functional impact. NBS Nytt. Tidsskrift for norsk biokjemiskselskap NBS Nytt. Tidsskrift for norsk biokjemiskselskap [Business/trade/industry journal] 2015-09-14
  • Academic lecture
    Hansen, Marianne Dore; Johnsen, Ingvild Bjellmo; Stiberg, Kim Andre Ha; Malmo, Jostein; Sherstova, Tatyana; Meurs, Eliane F.. (2015) Hepatitis C virus infection remodels the Golgi complex to trigger autophagy through the immunity-related GTPase M. 22nd International Symposium on Hepatitis C Virus and Related Viruses , Strasbourg 2015-10-09 - 2015-10-13

2013

  • Poster
    Hansen, Marianne Dore; Johnsen, Ingvild Bjellmo; Meurs, Eliane F.; Anthonsen, Marit Walbye. (2013) The interplay between HCV proteins, autophagy and innate immune response during HCV infection. Keystone Keystone Symposia - Autophagy, Inflammation and Immunity , Montreal 2013-02-17 - 2013-02-22
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