2025

• Cilla, Savino; Rossi, Romina; Donati, Costanza Maria; Habberstad, Ragnhild Hansdatter; Klepstad, Pål; Dall’Agata, Monia. (2025) Pain Management Adequacy in Patients With Bone Metastases: A Secondary Analysis From the Palliative Radiotherapy and Inflammation Study Trial. Clinical Medicine Insights: Oncology
  Academic article
• Hofstad, Janne Kristin; Wik, Tina Strømdal; Klepstad, Pål; Gjeilo, Kari Hanne; Winther, Siri Bjørgen; Foss, Olav A.. (2025) In-Hospital Pain and Opioid Consumption After Primary Total Knee Arthroplasty Compared to Primary Total Hip Arthroplasty: Results from 7330 Patients Treated in a Fast-Track Setting. Pain and Therapy
  Academic article
• Minnai, Francesca; Shkodra, Morena; Noci, Sara; Esposito, Martina; Brunelli, Cinzia; Pigni, Alessandra. (2025) A genome-wide association study of European advanced cancer patients treated with opioids identifies regulatory variants on chromosome 20 associated with pain intensity. European Journal of Pain
  Academic article
• Kotlińska-Lemieszek, Aleksandra; Klepstad, Pål; Haugen, Dagny Renata Faksvåg. (2025) Clinically significant drug–drug interactions involving opioid analgesics used for pain treatment in patients with cancer: update of a systematic review. Expert Opinion on Drug Metabolism & Toxicology
  Academic literature review
• Darfelt, Iben Strøm; Neergaard, Mette Asbjoern; Klepstad, Pål; Hästbacka, Johanna; Thorarensen, Gunnar; Robertson, Andrew Campbell. (2025) Consensus statements on end-of-life care in ICU – A Scandinavian multidisciplinary Delphi study. Acta Anaesthesiologica Scandinavica
  Academic article

2024

• Cilla, Savino; Rossi, Romina; Habberstad, Ragnhild Hansdatter; Klepstad, Pål; Dall'Agata, Monia; Kaasa, Stein. (2024) Explainable Machine Learning Model to Predict Overall Survival in Patients Treated With Palliative Radiotherapy for Bone Metastases. JCO Clinical Cancer Informatics
  Academic article
• Rossi, Romina; Medici, Federica; Habberstad, Ragnhild Hansdatter; Klepstad, Pål; Cilla, Savino; Dall'Agata, Monia. (2024) Development of a predictive model for patients with bone metastases referred to palliative radiotherapy: Secondary analysis of a multicenter study (the PRAIS trial). Cancer Medicine
  Academic article
• Anthon, Carl Thomas; Pène, Frédéric; Perner, Anders; Azoulay, Elie; Puxty, Kathryn; Van De Louw, Andry. (2024) Platelet transfusions in adult ICU patients with thrombocytopenia: A sub-study of the PLOT-ICU inception cohort study. Acta Anaesthesiologica Scandinavica
  Academic article
• Minnai, Francesca; Shkodra, Morena; Noci, Sara; Brunelli, Cinzia; Pigni, Alessandra; Zecca, Ernesto. (2024) Genomic Study in Opioid-Treated Cancer Patients Identifies Variants Associated With Nausea-Vomiting. Journal of Pain and Symptom Management
  Academic article
• Urrizola, Amaia; Dajani, Olav; Aass, Nina Kathrine; Bjerkeset, Ellen; Hjermstad, Marianne Jensen; Kaasa, Stein. (2024) Nutrition impact symptom monitoring and weight loss outcomes: a longitudinal radiotherapy study. BMJ Supportive & Palliative Care
  Academic article
• Wong, Aaron K.; Vogrin, Sara; Klepstad, Pål; Rubio, Justin; Le, Brian; Philip, Jennifer. (2024) Do CYP2D6 genotypes affect oxycodone dose, pharmacokinetics, pain, and adverse effects in cancer?. Pharmacogenomics (London)
  Academic article
• Wong, Aaron K.; Klepstad, Pål; Somogyi, Andrew A.; Vogrin, Sara; Rubio, Justin; Le, Brian. (2024) Influence of COMT (rs4680) and OPRM1 (rs1799971) on Cancer Pain, Opioid Dose, and Adverse Effects. Journal of Palliative Medicine
  Academic article
• Darfelt, Iben Strøm; Nielsen, Anne Højager; Klepstad, Pål; Neergaard, Mette Asbjoern. (2024) A window of opportunity for ICU end-of-life care—A retrospective multicenter cohort study. Acta Anaesthesiologica Scandinavica
  Academic article
• Barratt, Daniel T.; Klepstad, Pål; Dale, Ola; Kaasa, Stein; Somogyi, Andrew A.. (2024) Pharmacokinetic and neuroimmune pharmacogenetic impacts on slow-release morphine cancer pain control and adverse effects. The Pharmacogenomics Journal
  Academic article
• Aalberg, Ingrid; Nordseth, Trond; Klepstad, Pål; Rosseland, Leiv Arne; Uleberg, Oddvar. (2024) Incidence, severity and changes of abnormal vital signs in trauma patients: A national population-based analysis. Injury
  Academic article
• Farbu, Bjørn Hoftun; Lydersen, Stian; Mohus, Randi Marie; Ueland, Thor; Mollnes, Tom Eirik; Klepstad, Pål. (2024) The detrimental effects of intestinal injury mediated by inflammation are limited in cardiac arrest patients: A prospective cohort study. Resuscitation Plus
  Academic article
• Klepstad, Pål. (2024) Henging. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Academic article
• Kroken, Bjørn Anders; Bergum, Daniel; Berg, Kristin Sandal; Espinasse, Marina; Fossum, Ole Kristian; Garratt, Andrew. (2024) Frailty and health-related life quality in long-term follow up of intensive care patients above 65 years old: Protocol for a Norwegian prospective, observational multicenter study. Acta Anaesthesiologica Scandinavica
  Article in business/trade/industry journal

2023

• Løhre, Erik Torbjørn; Jakobsen, Gunnhild; Solheim, Tora Skeidsvoll; Klepstad, Pål; Thronæs, Morten. (2023) Breakthrough and Episodic Cancer Pain from a Palliative Care Perspective. Current Oncology
  Academic article
• Wong, Aaron K.; Klepstad, Pål; Somogyi, Andrew A.; Vogrin, Sara; Le, Brian; Philip, Jennifer. (2023) Effect of gene variants on opioid dose, pain and adverse effect outcomes in advanced cancer: an explorative study. Pharmacogenomics (London)
  Academic article
• Fagertun, Henriette; Klepstad, Pål; Nyrønning, Linn Åldstedt; Seternes, Arne. (2023) Increasing Use of Prophylactic Open Abdomen Therapy With Vacuum Assisted Wound Closure and Mesh Mediated Fascial Traction After Repair of Ruptured Abdominal Aortic Aneurysm. European Journal of Vascular and Endovascular Surgery
  Academic article
• Hofstad, Janne Kristin; Klaksvik, Jomar; Klepstad, Pål; Gjeilo, Kari Hanne; Søballe, K; Wik, Tina Strømdal. (2023) Patient-reported outcomes the first thirty days after fast-track primary total hip arthroplasty. A prospective cohort study using a web-based registration tool for postoperative follow-up. International Journal of Orthopaedic and Trauma Nursing
  Academic article
• Wong, Aaron K.; Vogrin, Sara; Le, Brian; Klepstad, Pål; Rubio, Justin P; Somogyi, A. (2023) Background and Breakthrough Opioid Choice May Determine Different Pain Outcomes. Journal of Pain and Symptom Management
  Short communication
• Wong, Aaron K.; Klepstad, Pål; Rubio, Justin P.; Somogyi, Andrew A.; Vogrin, Sara; Le, Brian. (2023) Opioid Switch Dosing in Chronic Cancer Pain: A Prospective Longitudinal Study. Journal of Palliative Medicine
  Academic article
• Yu, Jinyang; Tannvik, Tomas Dybos; Klepstad, Pål. (2023) Avklaring av høyt noradrenalinbehov hos en pasient etter hjertekirurgi med blødningshistorie og redusert venstre ventrikkelfunksjon. NAForum
  Abstract
• Anthon, Carl Thomas; Pène, Frédéric; Perner, Anders; Azoulay, Elie; Puxty, Kathryn; Van De Louw, Andry. (2023) Thrombocytopenia and platelet transfusions in ICU patients: an international inception cohort study (PLOT-ICU). Intensive Care Medicine
  Academic article
• Anthon, Carl Thomas; Pène, Frédéric; Perner, Anders; Azoulay, Elie; Puxty, Kathryn; Van De Louw, Andry. (2023) Correction: Thrombocytopenia and platelet transfusions in ICU patients: an international inception cohort study (PLOT-ICU) (Intensive Care Medicine, (2023), 49, 11, (1327-1338), 10.1007/s00134-023-07225-2). Intensive Care Medicine
  Errata
• Fjøsne, Kari; Klepstad, Pål; Gjeilo, Kari Hanne. (2023) Lindrende behandling i livets sluttfase på en intensivavdeling − et kvalitetsprosjekt. Sykepleien Forskning
  Academic article
• Farbu, Bjørn Hoftun; Langeland, Halvor; Ueland, Thor; Michelsen, Annika Elisabet; Krüger, Andreas Jørstad; Klepstad, Pål. (2023) Intestinal injury in cardiac arrest is associated with multiple organ dysfunction: A prospective cohort study. Resuscitation
  Academic article
• Løhre, Erik Torbjørn; Svedahl, Augstein; Jakobsen, Gunnhild; Solheim, Tora S; Klepstad, Pål; Thronæs, Morten. (2023) Emergency Palliative Cancer Care: Dexmedetomidine Treatment Experiences—A Retrospective Brief Report on Nine Consecutive Cases. Pain and Therapy
  Academic article
• Wong, Aaron K.; Somogyi, Andrew A.; Rubio, Justin; Pham, Tien Dung; Le, Brian; Klepstad, Pål. (2023) Effectiveness of Opioid Switching in Advanced Cancer Pain: A Prospective Observational Cohort Study. Cancers
  Academic article
• Maltoni, Marco; Caraceni, Augusto Tomasso Giovanni; Klepstad, Pål; Rossi, Romina. (2023) Editorial: Early palliative care for cancer patients. Frontiers in Oncology
  Editorial
• Aslam, Tayyba Naz; Klitgaard, Thomas L.; Ahlstedt, Christian A. O.; Andersen, Finn Husøy; Chew, Michelle S.; Collet, Marie O.. (2023) A survey of preferences for respiratory support in the intensive care unit for patients with acute hypoxaemic respiratory failure. Acta Anaesthesiologica Scandinavica
  Academic article

2022

• Eggen, Idunn Banschbach; Brønstad, Gunhild; Langeland, Halvor; Klepstad, Pål; Nordseth, Trond. (2022) Short-term effects of endotracheal suctioning in post-cardiac arrest patients: A prospective observational cohort study. Resuscitation Plus
  Academic article
• Langeland, Halvor; Bergum, Daniel; Løberg, Magnus; Bjørnstad, Knut; Skaug, Thomas Renhult; Nordseth, Trond. (2022) Characteristics of circulatory failure after out-of-hospital cardiac arrest: A prospective cohort study. Open heart
  Academic article
• Jakobsen, Gunnhild; Gjeilo, Kari Hanne; Hjermstad, Marianne Jensen; Klepstad, Pål. (2022) An Update on Prevalence, Assessment, and Risk Factors for Sleep Disturbances in Patients with Advanced Cancer—Implications for Health Care Providers and Clinical Research. Cancers
  Academic literature review
• Habberstad, Ragnhild H; Aass, Nina Kathrine; Mollnes, Tom Eirik; Damås, Jan Kristian; Brunelli, Cinzia; Rossi, Romina. (2022) Inflammatory Markers and Radiotherapy Response in Patients With Painful Bone Metastases. Journal of Pain and Symptom Management
  Academic article
• Jakobsen, Gunnhild; Sjue, Karin; Paulsen, Ørnulf; Kaasa, Stein; Hjermstad, Marianne Jensen; Klepstad, Pål. (2022) Zopiclone versus placebo for short-term treatment of insomnia in patients with advanced cancer-a double-blind, randomized placebo-controlled clinical multicenter phase IV trial. Supportive Care in Cancer
  Academic article
• Phillip, J; Wong, A; Pasanen, L; Somogyi, Andrew A.; Rubio, J; Klepstad, Pål. (2022) Establishing a Longitudinal Opioid Pharmacogenomic Registry for Cancer Patients: Feasibility and Acceptability. Journal of Palliative Medicine
  Academic article
• Bye, Asta; Bjerkeset, Ellen; Stensheim, Hanne; Loge, Jon Håvard; Hjermstad, Marianne Jensen; Klepstad, Pål. (2022) Benefits of Study Participation for Patients with Advanced Cancer Receiving Radiotherapy: A Prospective Observational Study. Palliative Medicine Reports (PMR)
  Academic article
• Mo, Skule; Bjelland, Thor Wilhelm; Nilsen, Tom Ivar Lund; Klepstad, Pål. (2022) Acute kidney injury in intensive care patients: Incidence, time course, and risk factors. Acta Anaesthesiologica Scandinavica
  Academic article
• Waagsbø, Bjørn; Stuve, Nora; Afset, Jan Egil; Klepstad, Pål; Mo, Skule; Heggelund, Lars. (2022) High levels of discordant antimicrobial therapy in hospital-acquired bloodstream infections is associated with increased mortality in an intensive care, low antimicrobial resistance setting. Infectious Diseases
  Academic article
• Aukland, Eirik Aasen; Klepstad, Pål; Aukland, Stein Magnus; Zamanzad Ghavidel, Fatemeh; Buanes, Eirik Alnes. (2022) Acute kidney injury in patients with COVID-19 in the intensive care unit: Evaluation of risk factors and mortality in a national cohort. BMJ Open
  Academic article
• Rian, Torbjørn; Sand, Kari; Skogvoll, Eirik; Klepstad, Pål; Wik, Tina Strømdal. (2022) A Web-Based Communication Tool for Postoperative Follow-up and Pain Assessment at Home After Primary Knee Arthroplasty: Feasibility and Usability Study. JMIR Formative Research
  Academic article
• Moen, Martine Kjølberg; Løhre, Erik T; Jakobsen, Gunnhild; Thronæs, Morten; Klepstad, Pål. (2022) Antibiotic Therapy in Integrated Oncology and Palliative Cancer Care: An Observational Study. Cancers
  Academic article

2021

• Thronæs, Morten; Løhre, Erik T; Kvikstad, Anne; Brenne, Elisabeth; Norvaag, Robin; Aalberg, Kathrine Othelie. (2021) Interventions and symptom relief in hospital palliative cancer care: results from a prospective longitudinal study. Supportive Care in Cancer
  Academic article
• Brede, Jostein Rødseth; Skulberg, Arne Kristian; Rehn, Marius; Thorsen, Kjetil; Klepstad, Pål; Tylleskär, Ida. (2021) REBOARREST, resuscitative endovascular balloon occlusion of the aorta in non-traumatic out-of-hospital cardiac arrest: a study protocol for a randomised, parallel group, clinical multicentre trial. Trials
  Academic article
• Andersen, Finn Husøy; Haaland, Øystein Ariansen; Klepstad, Pål; Flaatten, Hans. (2021) Frailty and survival in elderly intensive care patients in Norway. Acta Anaesthesiologica Scandinavica
  Academic article
• Habberstad, Ragnhild H; Frøseth, Trude Camilla Salvesen; Aass, Nina Kathrine; Bjerkeset, Ellen; Abramova, Tatiana Mikhailovna; Garcia-Alonso, Elena. (2021) Clinical Predictors for Analgesic Response to Radiotherapy in Patients with Painful Bone Metastases. Journal of Pain and Symptom Management
  Academic article
• Mostad, Dagmar; Klepstad, Pål; Follestad, Turid; Pleym, Hilde. (2021) Desflurane consumption with automated vapour control systems in two different anaesthesia machines. A randomized controlled study. Acta Anaesthesiologica Scandinavica
  Academic article
• Langeland, Halvor Johannes Breivik; Damås, Jan Kristian; Mollnes, Tom Eirik; Ludviksen, Judith K; Ueland, Thor; Michelsen, Annika Elisabet. (2021) The inflammatory response is related to circulatory failure after out-of-hospital cardiac arrest: A prospective cohort study. Resuscitation
  Academic article
• Brede, Jostein Rødseth; Skjærseth, Eivinn Årdal; Klepstad, Pål; Nordseth, Trond; Krüger, Andreas. (2021) Changes in peripheral arterial blood pressure after resuscitative endovascular balloon occlusion of the aorta (REBOA) in non-traumatic cardiac arrest patients. BMC Emergency Medicine
  Academic article
• Langeland, Halvor; Bergum, Daniel; Nordseth, Trond; Løberg, Magnus; Skaug, Thomas Renhult; Bjørnstad, Knut. (2021) Circulatory trajectories after out-of-hospital cardiac arrest: a prospective cohort study. BMC Anesthesiology
  Academic article
• Jakobsen, Gunnhild; Engstrøm, Morten; Hjermstad, Marianne Jensen; Rosland, Jan Henrik; Aass, Nina Kathrine; Albert, Eva. (2021) The short-term impact of methylprednisolone on patient-reported sleep in patients with advanced cancer in a randomized, placebo-controlled, double-blind trial. Supportive Care in Cancer
  Academic article

2020

• Klepstad, Pål; Thronæs, Morten; Løhre, Erik T. (2020) Breakthrough pain is not a fixed fraction of constant cancer pain. European Journal of Pain
  Editorial
• Andersen, Siri Kojen; Hustveit, Ragnhild; Frøland, Erlend; Uleberg, Oddvar; Kruger, Andreas; Klepstad, Pål. (2020) Improper monitoring and deviations from physiologic treatment goals in patients with brain injury in the early phases of emergency care. Journal of clinical monitoring and computing
  Academic article
• Fürst, Per; Lundström, Staffan; Klepstad, Pål; Strang, Peter. (2020) Continuous subcutaneous infusion for pain control in dying patients: experiences from a tertiary palliative care center. BMC Palliative Care
  Academic article
• Løhre, Erik T; Thronæs, Morten; Klepstad, Pål. (2020) Breakthrough cancer pain in 2020. Current opinion in supportive and palliative care
  Academic literature review
• Jakobsen, Gunnhild; Engstrøm, Morten; Klepstad, Pål. (2020) Søvnkvalitet hos pasienter med avansert kreftsykdom og kort forventet levetid - en observasjonsstudie med subjektive og objektive målemetoder for søvn. BestPractise Nordic oncologi/hematologi
  Article in business/trade/industry journal
• Rian, Torbjørn; Skogvoll, Eirik; Hofstad, Janne Kristin; Høvik, Lise Husby; Winther, Siri Bjørgen; Husby, Vigdis Schnell. (2020) Tapentadol versus oxycodone for postoperative pain treatment the first 7 days after total knee arthroplasty: a randomized clinical trial. Pain
  Academic article
• Colombo, Francesca; Pintarelli, Giulia; Galvan, Antonella; Noci, Sara; Corli, Oscar; Skorpen, Frank. (2020) Identification of genetic polymorphisms modulating nausea and vomiting in two series of opioid-treated cancer patients. Scientific Reports
  Academic article

2019

• Brede, Jostein Rødseth; Lafrenz, Thomas; Klepstad, Pål; Skjærseth, Eivinn Årdal; Nordseth, Trond; Søvik, Edmund. (2019) Feasibility of Pre-Hospital Resuscitative Endovascular Balloon Occlusion of the Aorta in Non-Traumatic Out-of-Hospital Cardiac Arrest. Journal of the American Heart Association (JAHA)
  Academic article
• Bauer, Philippe R.; Chevret, Sylvie; Yadav, Hemang; Mehta, Sangeeta; Pickkers, Peter; Bukan, Ramin Brandt. (2019) Diagnosis and outcome of acute respiratory failure in immunocompromised patients after bronchoscopy. European Respiratory Journal
  Academic article
• Habberstad, Ragnhild H; Hjermstad, Marianne Jensen; Brunelli, Cinzia; Kaasa, Stein; Bennett, Michael I; Pardon, Koen. (2019) Which factors can aid clinicians to identify a risk of pain during the following month in patients with bone metastases? A longitudinal analyses. Supportive Care in Cancer
  Academic article
• Kotlinska-Lemieszek, Aleksandra; Klepstad, Pål; Haugen, Dagny Faksvåg. (2019) Clinically significant drug-drug interactions involving medications used for symptom control in patients with advanced malignant disease: A systematic review. Journal of Pain and Symptom Management
  Academic literature review
• Klepstad, Pia Katrin; Nordseth, Trond; Sikora, Normunds; Klepstad, Pål. (2019) Use of national early warning score for observation for increased risk for clinical deterioration during post-ICU care at a surgical ward. Therapeutics and Clinical Risk Management
  Academic article
• Brede, Jostein Rødseth; Lafrenz, Thomas; Krüger, Andreas; SØVIK, EDMUND; Steffensen, Torjus Lines; Kriesi, Carlo. (2019) Resuscitative endovascular balloon occlusion of the aorta (REBOA) in non-traumatic out-of-hospital cardiac arrest: Evaluation of an educational programme. BMJ Open
  Academic article
• Thronæs, Morten; Balstad, Trude Rakel; Brunelli, Cinzia; Løhre, Erik Torbjørn; Klepstad, Pål; Vagnildhaug, Ola Magne. (2019) Pain management index (PMI)-does it reflect cancer patients' wish for focus on pain?. Supportive Care in Cancer
  Academic article
• Martin-Loeches, Ignacio; Lemiale, Virginie; Geoghegan, Pierce; McMahon, Mary Aisling; Pickkers, Peter; Soares, Marcio. (2019) Influenza and associated co-infections in critically ill immunosuppressed patients. Critical Care
  Academic article
• Kurita, Geana Paula; Sjøgren, Per Johan E; Klepstad, Pål; Mercadante, Sebastiano. (2019) Interventional techniques to management of cancer-related pain: Clinical and critical aspects. Cancers
  Academic article
• Uleberg, Oddvar; Klepstad, Pål; Pape, Kristine; Kristiansen, Thomas. (2019) The trauma system and the patient - a national, regional and individual perspective. Norwegian University of Science and Technology
  Doctoral dissertation
• Løhre, Erik Torbjørn; Thronæs, Morten; Brunelli, Cinzia; Kaasa, Stein; Klepstad, Pål. (2019) An in-hospital clinical care pathway with integrated decision support for cancer pain management reduced pain intensity and needs for hospital stay. Supportive Care in Cancer
  Academic article
• Dolan, Ross D.; Laird, Barry J.A.; Klepstad, Pål; Kaasa, Stein; Horgan, Paul G.; Paulsen, Ørnulf. (2019) An exploratory study examining the relationship between performance status and systemic inflammation frameworks and cytokine profiles in patients with advanced cancer. Medicine
  Academic article
• Frøland, Erlend; Nordseth, Trond; Krüger, Andreas; Klepstad, Pål; Uleberg, Oddvar. (2019) Physiological stability in patients with acute ischemic cerebral insult during the prehospital treatment phase. NTNU
  Medical Student Research Thesis
• Jakobsen, Gunnhild; Engstrøm, Morten; Thronæs, Morten; Løhre, Erik Torbjørn; Kaasa, Stein; Fayers, Peter. (2019) Sleep quality in hospitalized patients with advanced cancer: an observational study using self-reports of sleep and actigraphy. Supportive Care in Cancer
  Academic article
• Furst, Per; Lundstrom, S; Klepstad, Pål; Strang, Peter. (2019) The Use of Low-Dose Methadone as Add-On to Regular Opioid Therapy in Cancer-Related Pain at End of Life: A National Swedish Survey in Specialized Palliative Care. Journal of Palliative Medicine
  Academic article
• Habberstad, Ragnhild H; Frøseth, Trude Camilla Salvesen; Aass, Nina Kathrine; Bjerkeset, Ellen; Abramova, Tatiana Mikhailovna; Garcia-Alonso, Elena. (2019) Clinical predictors for analgesic response to radiotherapy in patients with painful bone metastases. Annals of Oncology
  Abstract

2018

• Jakobsen, Gunnhild; Engstrøm, Morten; Paulsen, Ørnulf; Sjue, Karin; Raj, Sunil Xavier; Thronæs, Morten. (2018) Zopiclone versus placebo for short-term treatment of insomnia in patients with advanced cancer: study protocol for a double-blind, randomized, placebo-controlled, clinical multicenter trial. Trials
  Academic article
• Langeland, Halvor; Bergum, Daniel; Løberg, Magnus; Bjørnstad, Knut; Damås, Jan Kristian; Mollnes, Tom Eirik. (2018) Transitions Between Circulatory States After Out-of-Hospital Cardiac Arrest: Protocol for an Observational, Prospective Cohort Study. JMIR Research Protocols
  Academic article
• Gjeilo, Kari Hanne; Stenseth, Roar; Wahba, Alexander; Lydersen, Stian; Klepstad, Pål. (2018) Long-term health-related quality of life and survival after cardiac surgery: A prospective study. Journal of Thoracic and Cardiovascular Surgery
  Academic article
• Uleberg, Oddvar; Pape, Kristine; Kristiansen, Thomas; Romundstad, Pål Richard; Klepstad, Pål. (2018) Population-based analysis of the impact of trauma on longer-term functional outcomes. British Journal of Surgery
  Academic article
• Habberstad, Ragnhild H; Frøseth, Trude Camilla Salvesen; Aass, Nina Kathrine; Abramova, Tatiana Mikhailovna; Baas, Theo; Mørkeset, Siri Tessem. (2018) The Palliative Radiotherapy and Inflammation Study (PRAIS) - Protocol for a longitudinal observational multicenter study on patients with cancer induced bone pain. BMC Palliative Care
  Academic article
• Haugland, Helge Nystad; Uleberg, Oddvar; Klepstad, Pål; Krüger, Andreas; Rehn, Marius. (2018) Quality measurement in physician-staffed emergency medical services: a systematic literature review. International Journal for Quality in Health Care
  Academic literature review
• Jakobsen, Gunnhild; Engstrøm, Morten; Fayers, Peter; Hjermstad, Marianne Jensen; Kaasa, Stein; Kloke, Marianne. (2018) Sleep quality with WHO Step III opioid use for cancer pain. BMJ Supportive & Palliative Care
  Academic article
• Brede, Jostein Rødseth; Lafrenz, Thomas; Kruger, Andreas; SØVIK, EDMUND; Steffensen, Torjus Lines; Kriesi, Carlo. (2018) Resuscitative Balloon Occlusion of the Aorta in Non-Traumatic out of Hospital Cardiac Arrest - Evaluation of an Educational Program. Circulation
  Abstract
• Kotlinska-Lemieszek, Aleksandra; Klepstad, Pål; Haugen, Dagny Faksvåg. (2018) Clinically significant drug-drug-interactions involving medications used for symptom control in patients with advanced malignant disease. A systematic review. Palliative Medicine
  Abstract
• Gutteridge, Timothy; Kumaran, Mahalakshmi; Ghosh, Sunita; Fainsinger, Robin; Klepstad, Pål; Tarumi, Yoko. (2018) Single-nucleotide polymorphisms in TAOK3 are associated with high opioid requirement for pain management in patients with advanced cancer admitted to a tertiary palliative care unit. Journal of Pain and Symptom Management
  Academic article
• Løhre, Erik Torbjørn; Hjermstad, Marianne Jensen; Brunelli, Cinzia; Knudsen, Anne Kari; Kaasa, Stein; Klepstad, Pål. (2018) Pain Intensity Factors Changing Breakthrough Pain Prevalence in Patients with Advanced Cancer: A Secondary Analysis of a Cross-Sectional Observational International Study . Pain and Therapy
  Academic article
• Estrup Olesen, Anne; Grønlund, Debbie; Gram, Mikkel; Skorpen, Frank; Drewes, Asbjørn Mohr; Klepstad, Pål. (2018) Prediction of opioid dose in cancer pain patients using genetic profiling: not yet an option with support vector machine learning. BMC Research Notes
  Academic article
• Furst, Per; Lundström, Staffan; Klepstad, Pål; Runesdottir, S; Strang, P. (2018) Improved pain control in terminally ill cancer patients by introducing low-dose oral methadone in addition to on-going opioid treatment. Journal of Palliative Medicine
  Academic article

2017

• Gunnarsdottir, Sigridur; Sigurdardottir, Valgerdur; Kloke, Marinne; Radbruch, Lukas; Sabatowski, Rainer; Kaasa, Stein. (2017) A multicenter study of attitudinal barriers to cancer pain management. Supportive Care in Cancer
  Academic article
• Andersen, Siri Kojen; Hustveit, Ragnhild; Frøland, Erlend; Uleberg, Oddvar; Krüger, Andreas; Klepstad, Pål. (2017) Improper monitoring and deviations from physiologic treatment goals in unconscious patients With brain injury in the early phases of emergency care. NAForum
  Abstract
• Haugland, Helge Nystad; Rehn, Marius; Klepstad, Pål; Krüger, Andreas Jørstad. (2017) Developing quality indicators for physician-staffed emergency medical services: a consensus process. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
  Academic article
• Haugdahl, Hege Selnes; Dahlberg, Helena; Klepstad, Pål; Storli, Sissel Lisa. (2017) The breath of life. Patients? experiences of breathing during and after mechanical ventilation. Intensive and Critical Care Nursing
  Academic article
• Raj, Sunil Xavier; Brunelli, Cinzia; Klepstad, Pål; Kaasa, Stein. (2017) COMBAT study - Computer based assessment and treatment - A clinical trial evaluating impact of a computerized clinical decision support tool on pain in cancer patients. Scandinavian Journal of Pain
  Academic article
• Paulsen, Ørnulf; Laird, Barry J; Aass, Nina Kathrine; Lea, Tor Erling; Fayers, Peter; Kaasa, Stein. (2017) The relationship between pro-inflammatory cytokines and pain, appetite and fatigue in patients with advanced cancer. PLOS ONE
  Academic article
• Andersen, Finn Husøy; Kvåle, Reidar; Flaatten, Hans; Klepstad, Pål. (2017) Intensive care for the very old : ICU admission triage and outcomes. Doktoravhandlinger ved NTNU (2017:166)
  Doctoral dissertation
• Gjeilo, Kari Hanne; Wahba, Alexander; Klepstad, Pål; Lydersen, Stian; Stenseth, Roar. (2017) Long-term health-related quality of life and survival in patients after cardiac surgery - a prospective cohort study. European Journal of Cardiovascular Nursing
  Abstract
• Uleberg, Oddvar; Kristiansen, Thomas; Pape, Kristine; Romundstad, Pål Richard; Klepstad, Pål. (2017) Trauma care in a combined rural and urban region: an observational study. Acta Anaesthesiologica Scandinavica
  Academic article
• Andersen, Finn H; Flaatten, Hans; Klepstad, Pål; Follestad, Turid; Strand, Kristian; Krüger, Andreas. (2017) Long-Term Outcomes after ICU Admission Triage in Octogenarians. Critical Care Medicine
  Academic article
• Haugland, Helge Nystad; Uleberg, Oddvar; Klepstad, Pål; Krüger, Andreas; Rehn, Marius. (2017) Kvalitetsmåling i legebemannede utrykningstjenester: en systematisk litteraturgjennomgang. NAForum
  Abstract
• Dale, Ola; Klepstad, Pål; Tveita, Torkjel; Thoner, Just; Borchgrevink, Petter Chr.. (2017) Re: fra ketobemidon til oksykodon. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Reader opinion piece

2016

• Seternes, Arne; Fasting, Sigurd; Klepstad, Pål; Mo, Skule; Dahl, Torbjørn; Bjørck, Martin. (2016) Bedside dressing changes for open abdomen in the intensive care unit is safe and time and staff efficient. Critical Care
  Academic article
• Seternes, Arne; Rekstad, Lars Cato; Mo, Skule; Klepstad, Pål; Halvorsen, Dag Linthoe; Dahl, Torbjørn. (2016) Open Abdomen Treated with Negative Pressure Wound Therapy: Indications, Management and Survival. World Journal of Surgery
  Academic article
• Skorpen, Frank; von Hofacker, Sebastian; Bjørngaard, Mads; Skogholt, Anne Heidi; Dale, Ola; Kaasa, Stein. (2016) The rare Arg181Cys mutation in the μ opioid receptor can abolish opioid responses. Acta Anaesthesiologica Scandinavica
  Academic article
• Klepstad, Pål; Skorpen, Frank. (2016) Genetic findings related to pain and analgesics-why are they so inconsistent?. Pain
  Book review
• Løhre, Erik T; Klepstad, Pål; Bennett, Michael I.; Brunelli, Cinzia; Caraceni, Augusto; Fainsinger, Robin L.. (2016) From "breakthrough" to "episodic" Cancer Pain? A European Association for Palliative Care Research Network Expert Delphi Survey Toward a Common Terminology and Classification of Transient Cancer Pain Exacerbations. Journal of Pain and Symptom Management
  Academic article
• Haugdahl, Hege Selnes; Storli, Sissel Lisa; Meland, Barbro; Dybwik, Knut Gustav; Romild, Ulla Kristina; Klepstad, Pål. (2016) Reply: Assessment of intensive care unit patients' experience of breathlessness. American Journal of Respiratory and Critical Care Medicine
  Letter to the editor
• Mercadante, Sebastiano; Klepstad, Pål; Kurita, Geana; Sjøgren, Per; Pigni, Alessandra; Caraceni, Augusto. (2016) Minimally invasive procedures for the management of vertebral bone pain due to cancer: The EAPC recommendations. Acta Oncologica
  Academic literature review
• Gjeilo, Kari Hanne; Stenseth, Roar; Wahba, Alexander; Lydersen, Stian; Klepstad, Pål. (2016) Chronic postsurgical pain in patients 5 years after cardiac surgery: A prospective cohort study. European Journal of Pain
  Academic article
• Løhre, Erik T; Klepstad, Pål; Bennett, Michael I.; Brunelli, Cinzia; Caraceni, Augusto; Fainsinger, Robin L.. (2016) Authors' Reply to Davies et al. Journal of Pain and Symptom Management
  Letter to the editor
• Rosland, Jan Henrik; Borchgrevink, Petter Chr.; Klepstad, Pål; Kongsgaard, Ulf. (2016) Smertebehandling hos pasienter som har kreft. Medikamentell kreftbehandling. Cytostatikaboken (8)
  Textbook
• Laird, Barry J; Fallon, Marie; Hjermstad, Marianne Jensen; Tuck, Sharon; Kaasa, Stein; Klepstad, Pål. (2016) Quality of life in patients with advanced cancer: Differential association with performance status and systemic inflammatory response. Journal of Clinical Oncology
  Academic article
• De Gregori, Manuela; Diatchenko, Luda; Ingelmo, Pablo M.; Napolioni, Valerio; Klepstad, Pål; Belfer, Inna. (2016) Human Genetic Variability Contributes to Postoperative Morphine Consumption. Journal of Pain
  Academic article
• Schirmer-Mikalsen, Kari; Vik, Anne; Skogvoll, Eirik; Moen, Kent Gøran; Solheim, Ole; Klepstad, Pål. (2016) Intracranial Pressure During Pressure Control and Pressure-Regulated Volume Control Ventilation in Patients with Traumatic Brain Injury: A Randomized Crossover trial. Neurocritical Care
  Academic article
• Alawneh, A; Tugan, W; Innabi, A; Al-Nimer, Y; Azzouqah, Ole; Rimawi, D. (2016) Clinical factors associated with a short survival time after percutaneous nephrostomy for ureteric obstruction in cancer patients: An updated model. Journal of Pain and Symptom Management
  Academic article
• Alawneh, Alia; Yasin, Hesham; Khirfan, Ghaleb; Qayas, Bashar Abu; Ammar, Khawla; Rimawi, Dalia. (2016) Psychometric properties of the Arabic version of EORTC QLQ-C15-PAL among cancer patients in Jordan. Supportive Care in Cancer
  Academic article
• Betten, Jan; Roness, Aleksander Kirkerud; Endreseth, Birger Henning; Trønnes, Håkon; Tyvold, Stig Sverre; Klepstad, Pål. (2016) Assessment of the time-dependent need for stay in a high dependency unit (HDU) after major surgery by using data from an anesthesia information management system. Journal of clinical monitoring and computing
  Academic article
• Kurita, Geana Paula; Ekholm, Ola; Kaasa, Stein; Klepstad, Pål; Skorpen, Frank; Sjøgren, Per. (2016) Genetic variation and cognitive dysfunction in opioid-treated patients with cancer. Brain and Behavior
  Academic article
• Dale, Ola; Klepstad, Pål; Tveita, Torkjel; Thoner, Just; Borchgrevink, Petter Chr.. (2016) Re: Fra ketobemidon til morfin eller oksykodon. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Letter to the editor

2015

• Andersen, Finn Husøy; Flaatten, Hans Kristian; Klepstad, Pål; Romild, Ulla Kristina; Kvåle, Reidar. (2015) Long-term survival and quality of life after intensive care for patients 80 years of age or older. Annals of Intensive Care
  Academic article
• MacLeod, Nicholas; Klepstad, Pål; Fallon, Marie; Laird, Barry J.. (2015) Pain mangement in mesothelioma. Journal of Palliative Care & Medicine
  Academic literature review
• Lee, Yong Joo; Suh, Sang-Yeon; Song, Junghan; Lee, Sanghee Shiny; Seo, Ah-Ram; Ahn, Hong-Yup. (2015) Serum and urine concentrations of morphine and morphine metabolites in patients with advanced cancer receiving continuous intravenous morphine: An observational study Cancer palliative care. BMC Palliative Care
  Academic article
• Halset, Jørgen Holli; Hanssen, Simon Wøhlert; Espinosa, Aurora; Klepstad, Pål. (2015) Tromboelastography: variability and relation to conventional coagulation test in non-bleeding intensive care unit patients. BMC Anesthesiology
  Academic article
• Kotlinska-Lemieszek, Aleksandra; Klepstad, Pål; Haugen, Dagny Faksvåg. (2015) Clinically significant drug–drug interactions involving opioid analgesics used for pain treatment in patients with cancer: A systematic review. Drug Design, Development and Therapy
  Academic literature review
• Kurita, GP; Benthien, KS; Nordly, M; Mercadante, S.; Klepstad, Pål; Sjøgren, P. (2015) The evidence of neuraxial administration of analgesics for cancer-related pain: A systematic review. Acta Anaesthesiologica Scandinavica
  Academic literature review
• Klepstad, Pål; Kurita, Geana; Mercadante, Sebastiano; Sjøgren, Per. (2015) Evidence of peripheral nerve blocks for cancer-related pain: a systematic review. Minerva Anestesiologica
  Academic literature review
• Klepstad, Pål; Habberstad, R. (2015) Bone cancer pain. The interaction between the tumor and the patient. Fighting Pain
  Academic literature review
• Klepstad, Pål; Skorpen, Frank. (2015) Genetic variability of pain - a patient focused endpoint. Scandinavian Journal of Pain
  Editorial
• Klepstad, Pål. (2015) Perifer blokade ved behandling av kreftsmerter. BestPractice Nordic
  Academic literature review
• Haugdahl, Hege Selnes; Storli, Sissel Lisa; Meland, Barbro; Dybwik, Knut; Romild, Ulla Kristina; Klepstad, Pål. (2015) Underestimation of patients breathlessness by nurses and physicians during a spontaneous breathing trial. American Journal of Respiratory and Critical Care Medicine
  Academic article
• Barratt, Daniel T.; Klepstad, Pål; Dale, Ola; Kaasa, Stein; Somogyi, Andrew A.. (2015) Innate immune signalling genetics of pain, cognitive dysfunction and sickness symptoms in cancer pain patients treated with transdermal fentanyl. PLOS ONE
  Academic article
• Mercadante, Sebastiano; Klepstad, Pål; Kurita, Geana; Sjøgren, Per; Giarratano, A. (2015) Sympathetic blocks for visceral cancer pain management: A systematic review and EAPC recommendations. Critical Reviews in Oncology/Hematology
  Academic article
• Klepstad, Pål; Skorpen, Frank. (2015) Genetic findings related to pain and analgesics – why are they so inconsistent?. Pain
  Editorial
• Stuedahl, Marit; Vold, Sissel; Stafseth, Siv Anna Ulla-Britt Karlsson; Klepstad, Pål. (2015) Interrater reliability of Nursing Activities Score among Intensive Care Unit health professionals. Revista da Escola de Enfermagem da USP
  Academic article
• Laugsand, Eivor Alette; Skorpen, Frank; Kaasa, Stein; Sabatowski, Rainer; Strasser, Florian; Fayers, Peter. (2015) Genetic and Non-genetic Factors Associated With Constipation in Cancer Patients Receiving Opioids. Clinical and Translational Gastroenterology
  Academic article
• Currow, David C.; Quinn, Stephen; Ekström, Magnus; Kaasa, Stein; Johnson, Miriam J.; Somogyi, Andrew A.. (2015) Can variability in the effect of opioids on refractory breathlessness be explained by genetic factors?. BMJ Open
  Academic article
• Kurita, GP; Lundström, S; Sjøgren, P; Ekholm, O; Christrup, L; Davies, A. (2015) Renal function and symptoms/adverse effects in opioid-treated patients with cancer. Acta Anaesthesiologica Scandinavica
  Academic article
• Kotlinska-Lemieszek, Aleksandra; Klepstad, Pål; Haugen, Dagny Faksvåg. (2015) Clinically significant drug-drug interactions involving opioids in patients with cancer: a systematic review. Abstract no P1-009. European Journal of Palliative Care
  Abstract
• Paulsen, Ørnulf; Aass, Nina Kathrine; Klepstad, Pål; Kaasa, Stein. (2015) Reply to A. Molfino et al. Journal of Clinical Oncology
  Letter to the editor
• Andersen, Finn H; Flaatten, Hans; Klepstad, Pål; Romild, Ulla Kristina; Kvåle, Reidar. (2015) Long-term survival and quality of life after intensive care for patients 80 years of age or older. Annals of Intensive Care
  Academic article

2014

• Jakobsen, Gunnhild; Knudsen, Anne Kari; Klepstad, Pål. (2014) Sleep disturbance in patients with advanced cancer disease.
  Website (informational material)
• Klepstad, Pål. (2014) Polymorphism in the mu-opioid receptor gene OPRM1 A118G. an example of the enigma og genetic variability behind chronic pain. Scandinavian Journal of Pain
  Editorial
• Klepstad, Pål. (2014) Pharmacokinetics and drug responses. Fighting Pain
  Academic literature review
• Scarpi, E; Calistri, D; Klepstad, Pål; Kaasa, Stein; Skorpen, Frank; Habberstad, Ragnhild Hansdatter. (2014) Clinical and genetic factors related to cancer-induced bone pain and bone pain relief. The Oncologist
  Academic article
• Sande, Tonje; Scott, A.C.; Laird, Barry J; Wan, H.I.; Fleetwood-Walker, S.M.; Kaasa, Stein. (2014) The characteristics of physical activity and gait in patients receiving radiotherapy in cancer induced bone pain. Radiotherapy and Oncology
  Academic article
• Haugdahl, Hege Selnes; Storli, Sissel Lisa; Dybwik, Knut; Klepstad, Pål. (2014) Pusten og livet. Trønder-avisa
  Feature article
• Gjeilo, Kari Hanne; Stenseth, Roar; Klepstad, Pål. (2014) Risk Factors and Early Pharmacological Interventions to Prevent Chronic Postsurgical Pain Following Cardiac Surgery. American Journal of Cardiovascular Drugs
  Academic article
• Jakobsen, Gunnhild; Knudsen, Anne Kari; Klepstad, Pål. (2014) Wake up, sleep is important! Managing sleep disturbance in patients with advanced cancer. European Journal of Palliative Care
  Academic article
• Sprangers, Mirjam A. G.; Thong, Melissa S. Y.; Bartels, Meike; Barsevick, Andrea; Ordonana, Juan; Shi, Quiling. (2014) Biological pathways, candidate genes, and molecular markers associated with quality-of-life domains: an update. Quality of Life Research
  Academic article
• Uleberg, Oddvar; Vinjevoll, Ole-Petter; Kristiansen, Thomas; Klepstad, Pål. (2014) Norwegian trauma care: a national cross-sectional survey of all hospitals involved in the management of major trauma patients. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
  Academic article
• Barratt, DT; Bandak, B; Klepstad, Pål; Dale, Ola; Kaasa, Stein; Christrup, Lona L. (2014) Genetic, pathological and physiological determinants of transdermal fentanyl pharmacokinetics in 620 cancer patients of the EPOS study. Pharmacogenetics & Genomics
  Academic article
• Krüger, Andreas; Uleberg, Oddvar; Klepstad, Pål. (2014) Interhospital transports of critically ill patients - the hospital perspective. Air Rescue Magazine
  Article in business/trade/industry journal
• Sandrød, Oddrun; Klepstad, Pål; Stenseth, Roar; Gjeilo, Kari Hanne. (2014) Survival and health-related quality of life in cardiac surgery patients with ICU length of stay more than one day. A 5-year follow-up study. European Journal of Cardiovascular Nursing
  Abstract
• Mulvey, Matthew R.; Rolke, Roman; Klepstad, Pål; Caraceni, Augusto; Fallon, Marie; Colvin, Lesley. (2014) Confirming neuropathic pain in cancer patients: Applying the NeuPSIG grading system in clinical practice and clinical research. Pain
  Academic literature review
• Kotlinska-Lemieszek, Aleksandra; Paulsen, Ørnulf; Kaasa, Stein; Klepstad, Pål. (2014) Polypharmacy in patients with advanced cancer and pain: A european cross-sectional study of 2282 patients. Journal of Pain and Symptom Management
  Academic article
• Paulsen, Ørnulf; Klepstad, Pål; Rosland, Jan Henrik; Aass, Nina Kathrine; Albert, Eva; Fayers, Peter. (2014) Efficacy of methylprednisolone on pain, fatigue, and appetite loss in patients with advanced cancer using opioids: A randomized, placebo-controlled, double-blind trial. Journal of Clinical Oncology
  Academic article
• Bjelland, Thor Wilhelm; Klepstad, Pål; Haugen, Bjørn Olav; Nilsen, Torbjørn; Salvesen, Øyvind; Dale, Ola. (2014) Concentrations of remifentanil, propofol, fentanyl, and midazolam during rewarming from therapeutic hypothermia. Acta Anaesthesiologica Scandinavica
  Academic article
• Raj, Sunil; Thronæs, Morten; Brunelli, Cinzia; Hjermstad, Marianne Jensen; Klepstad, Pål; Kaasa, Stein. (2014) A cross-sectional study on prevalence of pain and breakthrough pain among an unselected group of outpatients in a tertiary cancer clinic. Supportive Care in Cancer
  Academic article

2013

• Schirmer-Mikalsen, Kari; Moen, Kent Gøran; Skandsen, Toril; Vik, Anne; Klepstad, Pål. (2013) Intensive care and traumatic brain injury after the introduction of a treatment protocol: a prospective study. Acta Anaesthesiologica Scandinavica
  Academic article
• Fladvad, Torill; Klepstad, Pål; Langaas, Mette; Dale, Ola; Kaasa, Stein; Caraceni, Augusto. (2013) Variability in UDP-glucuronosyltransferase genes and morphine metabolism. Observations from a cross-sectional multicenter study in advanced cancer patients with pain. Pharmacogenetics & Genomics
  Academic article
• Klepstad, Pål; Hjermstad, Marianne Jensen. (2013) Are all patients that counts included in palliative care studies?. BMJ Supportive & Palliative Care
  Editorial
• Klepstad, Pål. (2013) Pharmacokinetics of opioids. Influenced by genetic variability. Minerva Anestesiologica
  Academic literature review
• Rao, Vidar; Klepstad, Pål; Losvik, Ole Kristian; Solheim, Ole. (2013) Confusion with cerebral perfusion pressure in a literature review of current guidelines and survey of clinical practise. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
  Academic article
• Laird, Barry J; Kaasa, Stein; McMillan, DC; Fallon, Marie T.; Hjermstad, Marianne Jensen; Fayers, Peter. (2013) Prognostic Factors in Patients with Advanced Cancer: A Comparison of Clinicopathological Factors and the Development of an Inflammation-Based Prognostic System. Clinical Cancer Research
  Academic article
• Storm, Hanne; Støen, Randi; Klepstad, Pål; Skorpen, Frank; Qvigstad, Erik; Ræder, Johan. (2013) Nociceptive stimuli responses at different levels of general anaesthesia and genetic variability. Acta Anaesthesiologica Scandinavica
  Academic article
• Bjelland, Thor Wilhelm; Klepstad, Pål; Haugen, Bjørn Olav; Nilsen, Turid; Dale, Ola. (2013) Effects of hypothermia on the disposition of morphine, midazolam, fentanyl, and propofol in intensive care unit patients. Drug Metabolism And Disposition
  Academic article
• Bakkelund, Karin Elvenes; Sundland, Erlend; Moen, Siv; Vangberg, Gunnar; Mellesmo, Sindre; Klepstad, Pål. (2013) Undertreatment of pain in the prehospital setting: a comparison between trauma patients and patients with chest pain. European journal of emergency medicine
  Academic article
• Salminen, Eeva; Silvoniemi, Maria; Syrjänen, Kari; Kaasa, Stein; Kloke, Marinne; Klepstad, Pål. (2013) Opioids in pain management of mesothelioma and lung cancer patients. Acta Oncologica
  Academic article
• Gjeilo, Kari Hanne; Wahba, Alexander; Klepstad, Pål; Lydersen, Stian; Stenseth, Roar. (2013) Survival and quality of life in an elderly cardiac surgery population: 5-year follow-up. European Journal of Cardio-Thoracic Surgery
  Academic article
• Laird, Barry J; McMillan, DC; Fayers, Peter; Fearon, Kenneth C.; Kaasa, Stein; Fallon, Marie T.. (2013) The Systemic Inflammatory Response and Its Relationship to Pain and Other Symptoms in Advanced Cancer. The Oncologist
  Academic article
• Bjelland, Thor Wilhelm; Hjertner, Øyvind; Klepstad, Pål; Kaisen, Kjell; Dale, Ola; Haugen, Bjørn Olav. (2013) Clopidogrel does not work following cardiopulmonary resuscitation. European Journal of Clinical Pharmacology
  Reader opinion piece
• Nekolaichuk, Cheryl; Fainsinger, Robin; Aass, Nina Kathrine; Hjermstad, Marianne Jensen; Knudsen, Anne Kari; Klepstad, Pål. (2013) The Edmonton Classification System for Cancer Pain: Comparison of Pain Classification Features and Pain Intensity Across Diverse Palliative Care Settings in Eight Countries. Journal of Palliative Medicine
  Academic article

2012

• Gjeilo, Kari Hanne; Wahba, Alexander; Klepstad, Pål; Lydersen, Stian; Stenseth, Roar. (2012) Recovery patterns and health-related quality of life in older patients undergoing cardiac surgery: a prospective study. European Journal of Cardiovascular Nursing
  Academic article
• Andreassen, Trine Naalsund; Eftedal, Ingrid; Klepstad, Pål; Davies, Andrew; Bjordal, Kristin; Lundström, Staffan. (2012) Do CYP2D6 genotypes reflect oxycodone requirements for cancer patients treated for cancer pain? A cross-sectional mutlicentre study. European Journal of Clinical Pharmacology
  Academic article
• Galvan, A; Fladvad, Torill; Skorpen, Frank; Gao, X; Klepstad, Pål; Kaasa, Stein. (2012) Genetic clustering of European cancer patients indicates that opioid-mediated pain relief is independent of ancestry. The Pharmacogenomics Journal
  Academic article
• Bjelland, Thor Wilhelm; Dale, Ola; Kaisen, Kjell; Haugen, Bjørn Olav; Lydersen, Stian; Strand, Kristian. (2012) Propofol and remifentanil versus midazolam and fentanyl for sedation during therapeutic hypothermia after cardiac arrest: a randomised trial. Intensive Care Medicine
  Academic article
• Knudsen, Anne Kari; Brunelli, C; Klepstad, Pål; Aass, Nina Kathrine; Apolone, Giovanni; Corli, Oscar. (2012) Which domains should be included in a cancer pain classification system? Analyses of longitudinal data. Pain
  Academic article
• Caraceni, Augusto; Hanks, Geoffrey; Kaasa, Stein; Bennett, Michael I; Brunelli, C; Cherny, Nathan. (2012) Use of opioid analgesics in the treatment of cancer pain: evidence-based recommendations from the EAPC. The Lancet Oncology
  Academic literature review
• Knudsen, Anne Kari; Klepstad, Pål; Aass, Nina Kathrine; Brunelli, C; Caraceni, Augusto; Kaasa, Stein. (2012) Classification and assessment of cancer pain. IASP Refresher Course Book
  Abstract
• Gjeilo, Kari Hanne; Wahba, Alexander; Klepstad, Pål; Lydersen, Stian; Stenseth, Roar. (2012) Health-related quality of life and survival in patients five years after cardiac surgery- a prospective cohort study. European Journal of Cardiovascular Nursing
  Abstract
• Knudsen, Anne Kari; Aass, Nina Kathrine; Heitzer, Ellen; Klepstad, Pål; Hjermstad, Marianne Jensen; Schippinger, Walter. (2012) Interviews with patients with advanced cancer-another step towards an international cancer pain classification system. Supportive Care in Cancer
  Academic article
• Klepstad, Pål. (2012) Anaesthesia, intensive care, and pain management for the cancer patient. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Book review
• Klepstad, Pål; Kaasa, Stein. (2012) The importance of and pitfalls of correlational science in palliative care research. Current opinion in supportive and palliative care
  Academic literature review
• Solheim, Tora Skeidsvoll; Fayers, Peter; Fladvad, Torill; Tan, Ben; Skorpen, Frank; Fearon, Kenneth C.. (2012) Is there a genetic cause of appetite loss? - An explorative study in 1853 cancer patients. Journal of Cachexia, Sarcopenia and Muscle
  Academic article
• Fladvad, Torill; Fayers, Peter; Skorpen, Frank; Kaasa, Stein; Klepstad, Pål. (2012) Lack of association between genetic variability and multiple pain-related outcomes in a large cohort of patients with advanced cancer disease –The European Pharmacogenetic Opioid Study (EPOS). BMJ Supportive & Palliative Care
  Academic article
• Klepstad, Pål. (2012) Start av opioider til kreftpasienter. Best Practice Smerte
  Article in business/trade/industry journal
• Klepstad, Pål. (2012) Start av opioider til kreftpasienter. Best Practice Onkologi/Hematologi
  Article in business/trade/industry journal
• Klepstad, Pål. (2012) Symptomkontrol i palliativ medicin. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Book review
• Knudsen, Anne Kari; Klepstad, Pål; Caraceni, Augusto; Kaasa, Stein; Brunelli, C; Aass, Nina Kathrine. (2012) Cancer pain undertreatment and prognostic factors Response. Pain
  Reader opinion piece
• Andreassen, Trine Naalsund; Klepstad, Pål; Davies, Andrew; Bjordal, Kristin; Lundström, Staffan; Kaasa, Stein. (2012) Is Oxycodone Efficacy Reflected in Serum Concentrations? A Multicenter, Cross-Sectional Study in 456 Adult Cancer Patients. Journal of Pain and Symptom Management
  Academic article

2011

• Laugsand, Eivor Alette; Jakobsen, Gunnhild; Kaasa, Stein; Klepstad, Pål. (2011) Inadequate symptom control in advanced cancer patients across Europe. Supportive Care in Cancer
  Academic article
• Knudsen, Anne Kari; Brunelli, C; Kaasa, Stein; Apolone, G.; Corli, O; Montanari, M. (2011) Which variables are associated with pain intensity and treatment response in advanced cancer patients? - Implications for a future classification system for cancer pain. European Journal of Pain
  Academic article
• Klepstad, Pål; Rosland, Jan Henrik. (2011) No pain, much gain. Acta Anaesthesiologica Scandinavica
  Editorial
• Perner, Anders; Haase, Nicolai; Wetterslev, Jørn; Åneman, Anders; Tenhunen, Jyrki; Guttormsen, Anne Berit. (2011) Comparing the effect of hydroxyethyl starch 130/0.4 with balanced crystalloid solution on mortality and kidney failure in patients with severe sepsis (6S-Scandinavian Starch for Severe Sepsis/Septic Shock trial): Study protocol, design and rationale for a double-blinded, randomised clinical trial. Trials
  Academic article
• Laugsand, Eivor Alette; Kaasa, Stein; Klepstad, Pål. (2011) Management of opioid-induced nausea and vomiting in cancer patients: systematic review and evidence-based recommendations. Palliative Medicine
  Academic literature review
• Fayers, Peter; Hjermstad, Marianne Jensen; Klepstad, Pål; Loge, Jon Håvard; Caraceni, Augusto; Hanks, Geoffrey. (2011) The dimensionality of pain: Palliative care and chronic pain patients differ in their reports of pain intensity and pain interference. Pain
  Academic article
• Kaasa, Stein; Apolone, Giovanni; Klepstad, Pål; Loge, Jon Håvard; Hjermstad, Marianne Jensen; Corli, Oscar. (2011) Expert conference on cancer pain assessment and classification - the need for international consensus: working proposals on international standards. BMJ Supportive & Palliative Care
  Academic article
• Nekolaichuk, Cheryl; Fainsinger, Robin; Aass, Nina Kathrine; Hjermstad, Marianne Jensen; Knudsen, Anne Kari; Klepstad, Pål. (2011) The Edmonton Classification System for Cancer Pain: Comparison of Pain Classification Features Across Diverse Palliative Care Settings in Eight Countries. European Journal of Palliative Care
  Abstract
• Laugsand, Eivor Alette; Klepstad, Pål; Skorpen, Frank; Kaasa, Stein. (2011) Symptoms in patients receiving opioids for cancer pain - clinical and pharmacogenetic aspects. NTNU - Trondheim
  Doctoral dissertation
• Kurita, Geana; Sjøgren, Per; Ekholm, Ola; Kaasa, Stein; Loge, Jon Håvard; Klepstad, Pål. (2011) Effects of Low-Dose Opioids on Cognitive Dysfunction Reply. Journal of Clinical Oncology
  Reader opinion piece
• Wahba, Alexander; Gjeilo, Kari Hanne; Klepstad, Pål; Lydersen, Stian; Stenseth, Roar. (2011) Helserelatert livskvalitet og overlevelse hos pasienter 5 år etter hjertekirurgi - en prospektiv kohortstudie. Vitenskapelige forhandlinger - De norske kirurgiske foreninger
  Abstract
• Klepstad, Pål. (2011) Bokanmeldelse: Væske, elektrolytter, blodgasser og infusjonsterapi. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Book review
• Klepstad, Pål. (2011) Bokanmeldelse: Drugs in anaesthesias and intensive care. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Book review
• Klepstad, Pål; Mathiesen, Ellisiv B.. (2011) Norsk klinisk helseforskning. En vei til bedre behandling og lavere utgifter?. Dagens medisin
  Feature article
• Husby, Kristin Moksnes; Dale, Ola; Rosland, Jan Henrik; Paulsen, Ørnulf; Klepstad, Pål; Kaasa, Stein. (2011) How to switch from morphine or oxycodone to methadone in cancer patients? A randomized clinical phase II trial. European Journal of Cancer
  Academic article
• Solheim, Tora Skeidsvoll; Fayers, Peter; Fladvad, Torill; Tan, B; Skorpen, Frank; Fearon, Ken. (2011) Is there a genetic cause for cancer cachexia? A clinical validation study in 1797 patients. British Journal of Cancer
  Academic article
• Andreassen, Trine Naalsund; Klepstad, Pål; Davies, Andrew; Bjordal, Kristin; Lundström, Staffan; Kaasa, Stein. (2011) Influences on the pharmacokinetics of oxycodone: a multicentre cross-sectional study in 439 adult cancer patients. European Journal of Clinical Pharmacology
  Academic article
• Kurita, Geana; Sjøgren, Per; Ekholm, Ola; Kaasa, Stein; Loge, Jon Håvard; Poviloniene, Irena. (2011) Prevalence and Predictors of Cognitive Dysfunction in Opioid-Treated Patients With Cancer: A Multinational Study. Journal of Clinical Oncology
  Academic article
• Galvan, A; Skorpen, Frank; Klepstad, Pål; Knudsen, Anne Kari; Fladvad, Torill; Falvella, Felicia S. (2011) Multiple Loci Modulate Opioid Therapy Response for Cancer Pain. Clinical Cancer Research
  Academic article
• Laugsand, Eivor Alette; Fladvad, Torill; Skorpen, Frank; Maltoni, M; Kaasa, Stein; Fayers, Peter. (2011) Clinical and genetic factors associated with nausea and vomiting in cancer patients receiving opioids. European Journal of Cancer
  Academic article
• Klepstad, Pål; Fladvad, Torill; Skorpen, Frank; Bjordal, Kristin; Caraceni, Augusto; Dale, Ola. (2011) Influence from genetic variability on opioid use for cancer pain: A European genetic association study of 2294 cancer pain patients. Pain
  Academic article
• Klepstad, Pål; Kaasa, Stein; Borchgrevink, Petter Chr.. (2011) Starting Step III opioids for moderate to severe pain in cancer patients: Dose titration: A systematic review. Palliative Medicine
  Academic literature review

2010

• Sletvold, Olav; Materstvedt, Lars Johan; Klepstad, Pål. (2010) Prisen på et liv. Aftenposten (morgenutg. : trykt utg.)
  Feature article
• Knudsen, Anne Kari; Aass, Nina Kathrine; Klepstad, Pål; Heitzer, Ellen; Hjermstad, Marianne Jensen; Schippinger, Walter. (2010) Advanced cancer patients' opinion on classification for cancer pain. Palliative Medicine
  Abstract
• Knudsen, Anne Kari; Brunelli, C; Apolone, G.; Corli, O; Montanari, M; Fainsinger, Robin. (2010) Content of a future classification system for cancer pain. Palliative Medicine
  Abstract
• Shi, Quiling; Cleeland, Charles; Klepstad, Pål; Miaskowski, Christine; Pedersen, Nancy. (2010) Biological pathways and genetic variables involved in pain. Quality of Life Research
  Academic article
• Carlsen, Anders Wetting; Haugen, Bjørn Olav; Klepstad, Pål. (2010) 71 år gammel mann med alvorlig sirkualasjonssvikt etter hjertestans. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Academic article
• Klepstad, Pål. (2010) Pharmacogenetic considerations in the treatment of cancer pain. Cambridge University Press
  Academic chapter/article/Conference paper
• Klepstad, Pål. (2010) Opioider og genetikk. NAForum
  Academic literature review
• Kurita, Geana; Sjøgren, Per; Ekholm, O; Kaasa, Stein; Loge, Jon Håvard; Poviloniene, I. (2010) Prevalence and predictors of cognitive dysfunction in opioid treated cancer patients. Palliative Medicine
  Abstract
• Fayers, Peter; Klepstad, Pål; Kaasa, Stein. (2010) The EPOS study: experiences in the statistical analysis of genetic association. Palliative Medicine
  Abstract
• Laugsand, Eivor Alette; Sprangers, MAG; Bjordal, Kristin; Skorpen, Frank; Kaasa, Stein; Klepstad, Pål. (2010) Health Care Providers Underestimate Symptom Intensities of Cancer Patients Recieving Palliative Care. Palliative Medicine
  Abstract
• Fayers, Peter; Klepstad, Pål; Kaasa, Stein. (2010) Are Studies in Palliative Care Biased? Characteristics of Patients Recruited to the EPOS Study. Palliative Medicine
  Abstract
• Klepstad, Pål. (2010) Intensivmedisinen og dens utfordringer. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Editorial
• Gjeilo, Kari Hanne; Stenseth, Roar; Klepstad, Pål; Lydersen, Stian; Wahba, Alexander. (2010) Patterns of smoking behaviour in patients following cardiac surgery. A prospective study. Scandinavian Cardiovascular Journal
  Academic article
• Pigni, Alessandra; Brunelli, C; Gibbins, Jane; Hanks, Geoffrey; DeConno, Franco; Kaasa, Stein. (2010) Content development for EUROPEAN GUIDELINES on the use of opioids for cancer pain: a systematic review and Expert Consensus Study. Minerva Anestesiologica
  Academic literature review
• Bjelland, Thor Wilhelm; Dale, Ola; Kaisen, K; Haugen, Bjørn Olav; Lydersen, Stian; Strand, K. (2010) REMIFENTANIL plus PROPOFOL VS. FENTANYL plus MIDAZOLAM FOR SEDATION DURING THERAPEUTIC HYPOTHERMIA: A RANDOMISED CONTROLLED TRIAL. Intensive Care Medicine
  Abstract
• Moksness, Kristin; Rosland, Jan Henrik; Paulsen, Ørnulf; Klepstad, Pål; Kaasa, Stein. (2010) How to switch from morphine or oxycodone to methadone. A randomized clinical phase III trial. Palliative Medicine
  Abstract
• Klepstad, Pål; Fladvad, Torill; Skorpen, Frank; Bjordal, Kristin; Caraceni, Augusto; Dale, Ola. (2010) The European Pharmacogenetic Opioid Study (EPOS): Influence from Genetic Variability on Opioid Use un 2209 Cancer Pain Patients. Palliative Medicine
  Abstract
• Lotsch, J; Klepstad, Pål; Doehring, A; Dale, Ola. (2010) A GTP cyclohydrolase 1 genetic variant delays cancer pain. Pain
  Academic article
• Bjelland, Thor Wilhelm; Hjertner, Øyvind; Klepstad, Pål; Kaisen, Kjell; Dale, Ola; Haugen, Bjørn Olav. (2010) Antiplatelet effect of clopidogrel is reduced in patients treated with therapeutic hypothermia after cardiac arrest. Resuscitation
  Academic article
• Laugsand, Eivor Alette; Sprangers, Mirjam A. G.; Bjordal, Kristin; Skorpen, Frank; Kaasa, Stein; Klepstad, Pål. (2010) Health care providers underestimate symptom intensities of cancer patients: A multicenter European study. Health and Quality of Life Outcomes
  Academic article
• Ytrebø, Lars Marius; Klepstad, Pål. (2010) Intensivbehandling av voksne med leversvikt. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Academic literature review
• Torgersen, Johan; Strand, Kristian; Bjelland, Thor W.; Klepstad, Pål; Kvåle, Reidar; Søreide, Eldar. (2010) Cognitive dysfunction and health-related quality of life after a cardiac arrest and therapeutic hypothermia. Acta Anaesthesiologica Scandinavica
  Academic article
• Carlsen, Anders Wetting; Haugen, Bjørn Olav; Klepstad, Pål. (2010) A.W. Carlsen og medarbeidere svarer. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Reader opinion piece
• Gjeilo, Kari Hanne; Klepstad, Pål; Wahba, Alexander; Lydersen, Stian; Stenseth, Roar. (2010) Chronic pain after cardiac surgery: a prospective study. Acta Anaesthesiologica Scandinavica
  Academic article

2009

• Klepstad, Pål. (2009) Start av behandling med opioider til kreftpasienter. Omsorg: Nordisk tidsskrift for Palliativ Medisin
  Academic literature review
• Dale, Ola; Piribauer, Maria; Kaasa, Stein; Husby, Kristin Moksnes; Knobel, Heidi; Klepstad, Pål. (2009) A Double-Blind, Randomized, Crossover Comparison Between Single-Dose and Double-Dose Immediate-Release Oral Morphine at Bedtime in Cancer Patients. Journal of Pain and Symptom Management
  Academic article
• Laugsand, Eivor Alette; Kaasa, Stein; De Conno, Franco; Hanks, Geoffrey; Klepstad, Pål. (2009) Intensity and treatment of symptoms in 3030 palliative care patients: A cross-sectional survey of the EAPC Research Network. Journal of Opioid Management
  Academic article
• Jaquet, Maria; Bjelland, Thor Wilhelm; Klepstad, Pål. (2009) ICG clearance egnet som mål på leverfunksjon hos intensivpasienter. NAForum
  Academic article
• Valeberg, Berit Taraldsen; Hanestad, Berit Rokne; Hanestad, Berit Rokne; Klepstad, Pål; Miaskowski, Christine; Moum, Torbjørn. (2009) Cancer patients’ barriers to pain management and psychometric properties of the Norwegian version of the Barriers Questionnaire. Scandinavian Journal of Caring Sciences
  Academic article
• Sprangers, Mirjam A. G.; Sloan, Jeff; Veenhoven, Ruut; Cleeland, Charles; Halyard, Michele Y; Abertnethy, Amy. (2009) The Establishment of the GENEQOL Consortium to Investigate the Genetic Disposition of Patient-Reported Quality-of-Life Outcomes. Twin Research and Human Genetics
  Academic article
• Lotsch, J; Klepstad, Pål; Doehring, A; Dale, Ola. (2009) A GTP cyclohydrolase 1 genetic variant delays cancer pain. Pain
  Academic article
• Knudsen, Anne Kari; Aass, Nina; Fainsinger, Robin; Caraceni, Augusto; Klepstad, Pål; Jordhøy, Marit S. (2009) Classification of pain in cancer patients - a systematic literature review. Palliative Medicine
  Academic article

2008

• Wahba, Alexander; Gjeilo, Kari Hanne; Klepstad, Pål; Lydersen, Stian; Karevold, Asbjørn; Astudillo, R.. (2008) En prospektiv undersøkelse av kjønnsforskjeller i livskvalitet før og etter hjertekirurgi. Vitenskapelige forhandlinger - De norske kirurgiske foreninger
  Abstract
• Bjelland, Thor Wilhelm; Klepstad, Pål; Haugen, Bjørn Olav; Nilsen, Turid; Dale, Ola. (2008) Serumkonsentrasjoner av morfin og midazolam hos pasienter under terapeutisk hypotermi. NAForum
  Abstract
• Storm, Hanne; Skorpen, Frank; Klepstad, Pål; Støen, Randi; Ræder, Johan. (2008) Genetically variation influence the skin conductance response to nociceptive pain in anesthetized patients. NAForum
  Abstract
• Skorpen, Frank; Laugsand, Eivor Alette; Klepstad, Pål; Kaasa, Stein. (2008) Variable response to opioid treatment: any genetic predictors within sight?. Palliative Medicine
  Abstract
• Klepstad, Pål; Kaasa, Stein. (2008) Prediction of cancer patients´survival by pain interference items is not the same as evidence that pain intensity is a survival predictor. Journal of Clinical Oncology
  Reader opinion piece
• Klepstad, Pål; Kaasa, Stein. (2008) Predication of cancer patients' survival by pain interference items is not the same as evidence that pain intensity is a survival predictor. Journal of Clinical Oncology
  Academic article
• Rakvag, Trude Teoline; Kaasa, Stein; Skorpen, Frank; Ross, Joy; Sato, H; Klepstad, Pål. (2008) Genetic variation in the catechol-O-methyltransferase (COMT) gene and morphine requirements in cancer patients. Palliative Medicine
  Academic article
• Bjelland, Thor Wilhelm; Klepstad, Pål; Haugen, Bjørn Olav; Nilsen, Turid; Dale, Ola. (2008) The disposition of morphine and midazolam in man during therapeutic hypothermia (33-34C). Intensive Care Medicine
  Academic article
• Husby, Kristin Moksnes; Fredheim, Olav Magnus; Klepstad, Pål; Kaasa, Stein; Angelsen, Anders; Nilsen, Turid. (2008) Early pharmacokinetics of nasal fentanyl: is there a significant arterio-venous difference?. European Journal of Clinical Pharmacology
  Academic article
• Hynninen, M; Klepstad, Pål; Petersson, Johan; Skram, Ulrik; Tallgren, Minna. (2008) Process of foregoing life-sustaining treatment: a survey among Scandinavian intensivists. Acta Anaesthesiologica Scandinavica
  Academic article
• Tveita, Torkjel; Thoner, Just; Klepstad, P; Dale, Ola; Jystad, A; jystad, a. (2008) A controlled comparison between single doses of intravenous and intramuscular morphine with respect to analgesic effects and patient safety. Acta Anaesthesiologica Scandinavica
  Academic article
• Rakvag, Trude Teoline; Ross, Joy R; Sato, Hiroe; Skorpen, Frank; Kaasa, Stein; Klepstad, Pål. (2008) Genetic variation in the Catechol-O-Methyltransferase (COMT) gene and morphine requirements in cancer pain patients. Molecular Pain
  Academic article
• Laugsand, Eivor Alette; Skorpen, Frank; Klepstad, Pål; Kaasa, Stein. (2008) Opioids in pain treatment - pharmacologic, genetic and clinical aspects. NTNU
  Medical Student Research Thesis
• Moen, Kent Gøran; Klepstad, Pål; Skandsen, Toril; Fredriksli, Oddrun; Vik, Anne. (2008) Direct transport versus interhospital transfer of patients with severe head injury in Norway. European journal of emergency medicine
  Academic article
• Gjeilo, Kari Hanne; Wahba, Alexander; Klepstad, Pål; Lydersen, Stian; Stenseth, Roar. (2008) The role of sex in health-related quality of life after cardiac surgery. European Journal of Cardiovascular Prevention & Rehabilitation
  Academic article
• Klepstad, Pål; Maltoni, M. (2008) Oppioidi: variabilita genetica efficacia.
  Academic chapter/article/Conference paper
• Hølen, Jacob Christian; Lydersen, Stian; Klepstad, Pål; Loge, Jon Håvard; Kaasa, Stein. (2008) The Brief Pain Inventory: Pain's Interference With Functions Is Different in Cancer Pain Compared With Noncancer Chronic Pain. The Clinical Journal of Pain
  Academic article
• Skorpen, Frank; Laugsand, Eivor Alette; Klepstad, Pål; Kaasa, Stein. (2008) Variable response to opioid treatment: any genetic predictors within sight?. Palliative Medicine
  Academic article

2007

• Funder Pedersen, Trine; Løberg Thorbjørnsen, M; Klepstad, Pål; Sunde, Kjetil; Dale, Ola. (2007) Terapeutisk hypotermi- farmakologi og patofysiologi. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Academic literature review
• Klepstad, Pål. (2007) Genetic variability and opioid efficacy. Current Anaesthesia and Critical Care
  Academic literature review
• Klepstad, Pål. (2007) Professional life in ICU Norwegian care. ICU management
  Academic literature review
• Gjeilo, Kari Hanne; Stenseth, Roar; Klepstad, Pål; Lydersen, Stian; Wahba, Alexander. (2007) Smoking cessation after cardiac surgery. A window of opportunity?. Hjerteposten : fagtidsskrift for NSFs landsgruppe av kardiologiske sykepleiere
  Abstract
• Gjeilo, Kari Hanne; Stenseth, Roar; Klepstad, Pål; Lydersen, Stian; Wahba, Alexander. (2007) Smoking cessation after cardiac surgery. A window of opportunity?. European Journal of Cardiovascular Nursing
  Abstract
• Dale, Ola; Thoner, J; Nilsen, T; Tveita, Torkjel; Borchgrevink, PC; Klepstad, P. (2007) Serum and cerebrospinal fluid morphine pharmacokinetics after single doses of intravenous and intramuscular morphine after hip replacement surgery. European Journal of Clinical Pharmacology
  Academic article
• Dale, Ola; Klepstad, Pål. (2007) Nye samtykkebestemmelser i biobankloven. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Academic article
• Stenseth, G; Bjornes, M; Kaasa, Stein; Klepstad, Pål. (2007) Can cancer patients assess the influence of pain on functions? A randomised, controlled study of the pain interference items in the Brief Pain Inventory. BMC Palliative Care
  Academic article
• Eide, Trine M. Olberg; Romundstad, Pål Richard; Klepstad, Pål; Myhre, Hans Olav. (2007) Helserelatert livskvalitet hos langtidsoverlevende etter kirurgi for torakoabdominalt aortaaneurisme. Tidsskriftet sykepleien
  Academic article
• Fredheim, Olav Magnus; Borchgrevink, Petter Chr.; Klepstad, Pål; Kaasa, Stein; Dale, Ola. (2007) Long term methadone for chronic pain: A pilot study of pharmacokinetic aspects. European Journal of Pain
  Academic article
• Reyes-Gibby, CC; Shete, S; Rakvag, Trude Teoline; Bhat, SV; Skorpen, Frank; Bruera, Eduardo. (2007) Exploring joint effects of genes and the clinical efficacy of morphine for cancer pain: OPRM1 and COMT gene. Pain
  Academic article
• Fredheim, Olav Magnus; Borchgrevink, Petter Chr.; Kaasa, Stein; Dale, Ola; Klepstad, Pål. (2007) Health related quality of life assessment and aspects of the clinical pharmacology of methadone in patients with chronic non-malignant pain. NTNU
  Doctoral dissertation
• Klepstad, Pål; Petersson, Johan. (2007) Palliasjon på en intensivavdeling. Gyldendal Akademisk
  Academic chapter/article/Conference paper
• Klepstad, Pål; Kaasa, Stein. (2007) Opioider. Gyldendal Akademisk
  Academic chapter/article/Conference paper
• Klepstad, Pål; Guttormsen, Anne Berit; Dale, O.. (2007) Common sense won: engagement from experts repealed Norwegian restrictions for ICU research. Intensive Care Medicine
  Academic article
• Klepstad, Pål; Guttormsen, Anne Berit; Dale, Ola. (2007) Common sense won; engagement from experts repealed Norwegian restrictions for ICU research. Intensive Care Medicine
  Academic article
• Gjeilo, Kari Hanne; Stenseth, Roar; Wahba, Alexander; Lydersen, Stian; Klepstad, Pål. (2007) Validation of the brief pain inventory in patients six months after cardiac surgery. Journal of Pain and Symptom Management
  Academic article
• Schirmer - Mikalsen, Kari; Vik, Anne; Gisvold, Sven Erik; Skandsen, Toril; Hynne, Hans; Klepstad, Pål. (2007) Severe head injury: control of physiological variables, organ failure and complications in the intensive care unit. Acta Anaesthesiologica Scandinavica
  Academic article

2006

• Schirmer - Mikalsen, Kari; Vik, Anne; Gisvold, Sven Erik; Hynne, Hans; Klepstad, Pål. (2006) Severe head injury: organ failure and complications in the intensive care unit. Journal of Neurotrauma
  Abstract
• Klepstad, Pål. (2006) Opioid analgesia: new insights. European Journal of Palliative Care
  Academic literature review
• Klepstad, Pål. (2006) Hva gjør en når håpet er ute?. Adresseavisen
  Feature article
• Gjeilo, Kari Hanne; Wahba, Alexander; Klepstad, Pål; Lydersen, Stian; Stenseth, Roar. (2006) Chronic pain after cardiac surgery. European Journal of Cardiovascular Nursing
  Abstract
• Reyes-Gibby, Cielito C; Shete, Sanjay; Rakvag, Trude Teoline; Bhat, Samrat V; Skorpen, Frank; Bruera, Eduardo. (2006) Exploring joint effects of genes and the clinical efficacy of morphine for cancer pain: OPRM1 and COMT gene. Pain
  Academic article
• Dale, Ola; Nilsen, Turid; Loftsson, Thorstein; Hjort Tønnesen, Hanne; Tønnesen, Hanne Hjorth; Klepstad, Pål. (2006) Intranasal midazolam: a comparison of two delivery devices in human volunteers. Journal of Pharmacy and Pharmacology (JPP)
  Academic article
• Fredheim, Olav Magnus; Husby, Kristin Moksnes; Kaasa, Stein; Borchgrevink, Petter Chr.; Klepstad, Pål. (2006) Opioidrotasjon og metadon i smertebehandling. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Academic article
• Fredheim, Olav Magnus; Borchgrevink, Petter Chr.; Hegrenaes, L; Kaasa, Stein; Dale, Ola; Klepstad, Pål. (2006) Opioid switching from morphine to methadone causes a minor but not clinically significant increase in QTc time: A prospective 9-month follow-up study. Journal of Pain and Symptom Management
  Academic article
• Gjeilo, Kari Hanne; Wahba, Alexander; Klepstad, Pål; Lydersen, Stian; Stenseth, Roar. (2006) Health-related quality of life three years after coronary surgery: A comparison with the general population. Scandinavian Cardiovascular Journal
  Academic article
• Fredheim, Olav Magnus; Kaasa, Stein; Dale, Ola; Klepstad, Pål; Landrø, Nils Inge; Borchgrevink, Petter Chr.. (2006) Opioid switching from oral slow release morphine to oral methadone may improve pain control in chronic non-malignant pain: a nine-month follow-up study. Palliative Medicine
  Academic article
• Klepstad, Pål; Dale, Ola. (2006) Further restriction for ICU research. Intensive Care Medicine
  Academic article
• Fredheim, Olav Magnus; Husby, Kristin Moksnes; Kaasa, Stein; Borchgrevink, Petter Chr.; Klepstad, Pål. (2006) Opioid switching and methadone in pain relief. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Academic article
• Fredheim, Olav Magnus; Borchgrevink, Petter Chr.; Klepstad, Pål; Kaasa, Stein; Dale, Ola. (2006) Long term methadone for chronic pain: A pilot study of pharmacokinetic aspects. European Journal of Pain
  Academic article
• Fredheim, Olav Magnus; Kaasa, Stein; Dale, Ola; Klepstad, Pål; Landrø, Nils Inge; Borchgrevink, Petter C. (2006) Opioid switching from oral slow release morphine to oral methadone may improve pain control in chronic non-malignant pain: a nine-month follow-up study. Palliative Medicine
  Academic article

2005

• Dale, Ola; Klepstad, Pål. (2005) Biobankloven stanser forskning på kritisk syke pasienter. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Reader opinion piece
• Dale, Ola; Klepstad, Pål; Kaasa, Stein. (2005) The European Union - not united in opioid use. Palliative Medicine
  Letter to the editor
• Gjeilo, Kari Hanne; Wahba, Alexander; Klepstad, Pål; Lydersen, Stian; Stenseth, Roar. (2005) Livskvalitet hos pasienter etter koronarkirurgi sammenlignet med normalbefolkningen. Hjerteforum
  Abstract
• Kaasa, Stein; Klepstad, Pål. (2005) Kreftpasienten skal ikke ha smerter. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Editorial
• Klepstad, Pål; Aurstad, Gunnhild Jacobsen. (2005) Genetisk variasjon- viktig for virkningen til opioider. Kreftsykepleien
  Academic literature review
• Kjesbu, Solveig Sandven; Husby, Kristin Moksnes; Klepstad, Pål; Knobel, Heidi; Kaasa, Stein; Dale, Ola. (2005) Bruk av pupillometri og pupillreaksjonar i medisinsk forsking. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Academic article
• Fayers, Peter; Hjermstad, Marianne Jensen; Ranhoff, Anette H; Kaasa, Stein; Skogstad, Laila; Klepstad, Pål. (2005) Which Mini-Mental State Exam (MMSE) items can be used in order to screen for delirium and cognitive impairment. Journal of Pain and Symptom Management
  Academic article
• Seland, Mette; Kaasa, Stein; Klepstad, Pål. (2005) Symptomregistrering hos kreftpasienter ved sykehusinnleggelse. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Academic article
• Klepstad, Pål; Dale, Ola; Borchgrevink, Petter Chr.; Kaasa, Stein; Skorpen, Frank. (2005) Genetisk variasjon - viktig for klinisk virkning av opioider?. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Academic article
• Klepstad, Pål; Kaasa, Stein; Cherny, Nathan; Hanks, Geoffrey; De Conno, Franco. (2005) Pain and pain treatments in European palliative care units. A cross sectional survey from the European Association for Palliative Care Research network. Palliative Medicine
  Academic article
• Dale, Ola; Klepstad, Pål. (2005) Sosial og helsedirektoratet stopper intensiv og akuttmedisinsk forskning. NAForum
  Academic article
• Klepstad, Pål; Dale, Ola; Borchgrevink, Petter Chr.; Kaasa, Stein; Skorpen, Frank. (2005) Genetic variability and clinical efficacy of morphine. Acta Anaesthesiologica Scandinavica
  Academic article
• Rakvag, Trude Teoline; Klepstad, Pål; Baar, Cecilie Christensen; Kvam, Tor-Morten; Dale, Ola; Kaasa, Stein. (2005) The Val158Met polymorphism of the human catechol-O-methyltransferase (COMT) gene may influence morphine requirements in cancer pain patients. Pain
  Academic article
• Eide, Trine Olberg; Romundstad, Pål Richard; Klepstad, Pål; Myhre, Hans Olav. (2005) Health related quality of life in long term-survivors following thoracoabdominal aortic aneurysm repair. Journal of Vascular Nursing
  Academic article
• Seland, Mette; Kaasa, Stein; Klepstad, Pål. (2005) Symptomregistrering hos kreftpasienter ved sykehusinnleggelse. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Academic article
• Fayers, Peter M; Hjermstad, Marianne Jensen; Ranhoff, Anette H; Kaasa, Stein; Skogstad, Laila; Klepstad, Pål. (2005) Which mini-mental state exam items can be used to screen for delirium and cognitive impairment?. Journal of Pain and Symptom Management
  Academic article

2004

• Klepstad, Pål. (2004) Genetyka a opioidy. Nowe dane pozwalajace na lepsze zrozumienie analgezji opioidowej. Polska Medycyna Paliatywna
  Academic literature review
• Borchgrevink, Petter Chr.; Klepstad, Pål; Kongsgaard, Ulf; Kaasa, Stein. (2004) Bruk av opioider mot sterke kreftrelaterte smerter. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Academic article
• Klepstad, Pål; Hilton, Priscilla; Moen, Jorunn; Kaasa, Stein; Borchgrevink, Petter Chr.; Zahlsen, Kolbjørn. (2004) Day-to-day variations during clinicaøl drug monitoring of morphine, morphine-3-glucuronide and morphine-6-glucuronide serum concentrations in cancer patients. A prospective observational study. BMC Clinical Pharmacology
  Academic article
• Klepstad, Pål; Rakvag, TT; Kaasa, Stein; Holthe, Monica; Dale, Ola; Borchgrevink, Petter Chr.. (2004) The 118 A>G polymorphism in the human mu-opioid receptor gene may increase morphins requirements in patients with pain caused by malignant disease. Acta Anaesthesiologica Scandinavica
  Academic article
• Borchgrevik, Petter C; Klepstad, Pål; Kongsgaard, Ulf; Kaasa, Stein. (2004) Bruk av opioider mot sterke kreftrelaterte smerter. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Academic article
• Klepstad, Pål; Rakvag, Trude Teoline; Kaasa, Stein; Holthe, Monica; Dale, Ola; Borchgrevink, Petter Chr.. (2004) The 118 A>G polymorphism in the human µ-opioidreceptor gene may increase morphine requrements in patients with pain caused by malignant disease. Acta Anaesthesiologica Scandinavica
  Academic article

2003

• Klepstad, Pål; Dale, Ola; Kaasa, Stein; Zahlsen, Kolbjørn; Aamo, T; Fayers, Peter. (2003) Influences on serum concentrations of morphine, M6G and M3G during routine clinical drug monitoring: A prospective survey in 300 adult cancer patients. Acta Anaesthesiologica Scandinavica
  Academic article
• Klepstad, Pål; Kaasa, Stein; Jystad, Åse; Hval, Bjørn; Borchgrevink, Petter Chr.. (2003) Immediate- or sustained-release morphine for dose finding during start of morphine to cancer patients: a randomized, double-blind trial. Pain
  Academic article
• Holthe, M.; Rakvåg, Trude Teoline; Klepstad, Pål; Idle, Jefrrey R.; Kaasa, Stein; Krokan, Hans Einar. (2003) Sequence variations in the UDP-glucuronosyltransferase 2B7 (UGT2B7) gene: identification of 10 novel single nucleotide polymorphisms (SNPs) and analysis of their relevance to morphine glucuronidation in cancer patients. The Pharmacogenomics Journal
  Academic article
• Klepstad, Pål; Gisvold, Sven Erik. (2003) End-of-life care in intensive care units. Save lives that can be saved, offer the dying a peaceful and dignified death. Acta Anaesthesiologica Scandinavica
  Academic article
• Holthe, Monica; Råkvåg, Trude Teoline; Klepstad, Pål; Idle, Jefrrey R.; Kaasa, Stein; Krokan, Hans Einar. (2003) Identification of 10 novel single nucleotide polymorphisms and analysis of their relevance to morphine glucuronidation. The Pharmacogenomics Journal
  Academic article
• Klepstad, Pål; Borchgrevink, Petter Chr.; Dale, Ola; Zahlsen, Kolbjørn; Aamo, Trond; Fayers, Peter. (2003) Routine drug monitoring of serum concentrations of morphine, morphine-3-glucuronide and morphine-6-glucuronide do not predict clinical obsevations in cancer patients. Palliative Medicine
  Academic article

2002

• Kaasa, Stein; Klepstad, Pål. (2002) Palliativ medisin i intensivavdelingen. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Feature article
• Klepstad, Pål; Loge, Jon Håvard; Borchgrevink, P.; Mendoza, T.; Cleeland, C.S.; Kaasa, Stein. (2002) The Norwegian Brief Pain Inventory questionnaire: translation and validation in cancer pain patients. Journal of Pain and Symptom Management
  Academic article
• Holthe, Monica; Klepstad, Pål; Zahlsen, Kolbjørn; Borchgrevink, Petter Chr.; Hagen, Lars; Dale, Ola. (2002) Morphine glucuronide-to-morphine plasma ratios are unaffected by the UGT2B7 H268Y and UGT1a1*28 polymorphisms in cancer patients on chronic morphine therapy. European Journal of Clinical Pharmacology
  Academic article
• Klepstad, Pål. (2002) Morfin for kreftsmerter. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Academic article
• Klepstad, Pål; Loge, Jon Håvard; Borchgrevink, Petter Chr.; Kaasa, Stein. (2002) The Norwegian Brief Pain Inventory. Translation and validation in cancer patients. Journal of Pain and Symptom Management
  Academic article
• Klepstad, Pål; Hilton, Pricilla; Moen, Jorunn; Fougner, Bjørn; Borchgrevink, Petter Chr.; Kaasa, Stein. (2002) Self-reports are not related to objective assessments of cognitive function and sedation in patients with cancer pain admitted to a palliative care unit. Palliative Medicine
  Academic article
• Holthe, Monica; Råkvåg, Trude Teoline; Klepstad, Pål; Idle, Jefrrey R.; Kaasa, Stein; Krokan, Hans Einar. (2002) Sequence variationin the UDP-glucuronosyltransferase 2B7 (UGT2B7) gene: identification of 10 novel single nucleotide polymorphins (SNPs) and analysis of their relevance to morphine glucuronidation in cancer patients. The Pharmacogenomics Journal
  Academic article
• Klepstad, Pål. (2002) Morphine for cancer pain. [Mangler utgivernavn]
  Doctoral dissertation

2001

• Klepstad, Pål; Borchgrevink, Petter Chr.; Hval, B; Flaat, S; Kaasa, Stein. (2001) Long-term treatment with ketamine to a 12-year-old girl with severe neuropathic pain caused by a cervical spinal tumour. Journal of Pediatric Hematology/Oncology
  Academic article

2000

• Klepstad, Pål; Kaasa, Stein; Skauge, M; Borchgrevink, Petter Chr.. (2000) Pain intensity and side effects during titration of morphine to cancer patients using a fixed schedule dose escalation. Acta Anaesthesiologica Scandinavica
  Academic article
• Klepstad, Pål; Borchgrevink, Petter Chr.; Kaasa, Stein. (2000) Effects on cancer patients health related quality of life from start of morphine. Journal of Pain and Symptom Management
  Academic article
• Klepstad, Pål; Kaasa, Stein; Borchgrevink, Petter Chr.. (2000) Role of morphine-6-glucuronide in morphine analgesia. European Journal of Clinical Pharmacology
  Academic article
• Klepstad, Pål; Kaasa, Stein; Borchgrevink, Petter Chr.. (2000) Start of oral morphine to cancer patients: Effective serum morphine concentrations and contribution from morphine-6-glucuronide to the analgesia produced by morphine. European Journal of Clinical Pharmacology
  Academic article
• Klepstad, Pål; Skogvoll, Eirik; Kaasa, Stein; Borchgrevink, Petter Chr.. (2000) Circadian distribution of oral opioid consumption in cancer patients. Methods and Findings in Experimental and Clinical Pharmacology
  Academic article

1999

• Klepstad, Pål. (1999) Relief of post dural puncture headache by an epidural blood patch administered 12 months after dural puncture. Acta Anaesthesiologica Scandinavica
  Academic article

1998

• Hole, Anton; Klepstad, Pål. (1998) Why monitor sedation in intensive care unit patients?.
  Academic chapter/article/Conference paper

1997

• Klepstad, Pål; Borchgrevink, P.C.. (1997) Four years' treatment with ketamine and a trial of dextromethorphan in a patient with severe post-herpetic neuralgia. Acta Anaesthesiologica Scandinavica
  Academic article
• Klepstad, Pål; Borchgrevink, Petter Chr.. (1997) Four years of treatment with ketamnine and a trial of dextromethorphane ine a patient with severe post-herpetic neuralgia. Acta Anaesthesiologica Scandinavica
  Academic article

1991

• Maurset, Atle; Skoglund, Lasse Ansgar; Hustveit, Olav; Klepstad, Pål; Øye, Ivar. (1991) A new version of the ischemic tourniquet pain test. Methods and Findings in Experimental and Clinical Pharmacology
  Academic article

1990

• Klepstad, Pål; Maurset, Atle; Moberg, Enrica Ratti; Øye, Ivar. (1990) Evidence for a role for NMDA receptors in pain perception. European Journal of Pharmacology
  Academic article

1988

• Klepstad, Pål; Øye, Ivar. (1988) ACE hemmere og livskvalitet. Er direkte effekter på sentralnerve systemet av betydning. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Academic literature review