Pål Sætrom

About

Pål Sætrom works to develop and use computational models to predict how changes in gene regulation can control development and cause disease.

Research

Sætrom’s research focuses on non-coding RNAs (ncRNAs) and their roles in gene regulation and disease. Three major areas of research are (i) developing and validating computer models that can predict how genetic variation affects gene regulation (Nucleic Acids Res, 2011; PLoS Comput Biol, 2012; Bioinformatics, 2014); (ii) understanding the roles of ncRNAs in epigenetics and cell cycle regulation (Nucleic Acids Res, 2013; DNA Repair, 2015); and (iii) designing artificial RNAs for targeted gene regulation and therapy (Mol Ther, 2010; RNA, 2010; Hepatology, 2014).

Biographical Sketch

Education/training

YEAR(s)	INSTITUTION AND LOCATION	DEGREE	FIELD OF STUDY
2005	NTNU, Trondheim, Norway	DPhil	Computer science (bioinformatics)
1996-2001	NTNU, Trondheim, Norway	M.Sc.	Computer science (algorithms)

Positions and Employment

2013-present	Adjunct Professor, Faculty of Biosciences and Aquaculture, University of Nordland, Norway
2012-present	Professor in bioinformatics, Department of Cancer Research and Molecular Medicine, NTNU, Trondheim, Norway
2011-present	Professor in bioinformatics, Department of Computer and Information Science, NTNU, Trondheim, Norway
2011	Guest researcher, Unit for Clinical Systems Biology, University of Gothenburg, Gothenburg, Sweden with Dr. Mikael Benson
2008-2011	Adjunct Associate Professor, Department of Computer and Information Science, NTNU, Trondheim, Norway
2007-2011	Post doctoral fellowship (Career development fellowships from NTNU and the Norwegian Research Council), Department of Cancer Research and Molecular Medicine, NTNU, Trondheim, Norway
2007	Adjunct Senior Lecturer, Department of Computer and Information Science, NTNU, Trondheim, Norway
2006-2007	Post doctoral fellowship (Leiv Erikson research scholarship from the Norwegian Research Council), Department of Molecular and Cellular Biology, City of Hope, Duarte, CA (12 months) with Prof. John J. Rossi
2002-2006	Research scientist, Interagon AS, Trondheim, Norway
2001-2002	Software Developer, Fast Search & Transfer ASA, Trondheim, Norway

Honors

2014	Outstanding Academic Fellow, NTNU
2008	PNAS Cozzarelli Prize in Biological Sciences (with D.H. Kim, O. Snøve, Jr., and J.J. Rossi)
2007-2010	Career research fellowship, Norwegian Functional Genomics Program (FUGE), Norwegian Research Council (NRC)
2007-2009	Career fellowship in Medical Technology, NTNU
2006	Research scholarship, FUGE, NRC
2006	Leiv Erikson research scholarship, NRC

Publications listed in publication databases

Publications

2026

Stahl, Margrethe Cecilie; Bergendahl, K.G.; Zaytseva-Zotova, Daria; Rytterager, K.R.; Nordgård, Catherine Taylor; Kjesbu, Joachim Sebastian; Haslene-Hox, Hanne; Halaas, Øyvind; Sætrom, P.; Chahal, Aman Singh. (2026) RGD-Alginate beads as scaffolds for culturing primary human dermal and pulmonary fibroblasts. Carbohydrate Polymers
Academic article

2025

Lien, Hilde Julie Tokle; Pedersen, Tina Therese; Jakobsen, Bente; Flatberg, Arnar; Leirvik, Gunnhild Vatne; Haug, Markus; Fenstad, Mona H.; Sætrom, Pål. (2025) Single-Cell RNA sequencing of pregnant women with SPRA and SLE: Uncovering cell-independent IFN signatures in SLE and a key role of MAIT and CD4 T-cells in SPRA. Frontiers in Lupus
Conference abstract
Lien, Hilde Julie Tokle; Sætrom, Pål; Fenstad, Mona Høysæter. (2025) Identifying cell type and gene expression changes in pregnant women with rheumatoid arthritis and systemic lupus erythematosus. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Lefol, Yohan Pierre; Hasle, Geir Amund; Hegre, Siv Anita; Samdal, Helle; Sætrom, Pål. (2025) Using pseudotime derivative on single-cell RNA sequencing data to identify genes undergoing cell cycle regulation. Bioinformatics Advances
Academic article
Hofsli, Eva; Sætrom, Pål; Ness-Jensen, Eivind; Surcel, Helja-Marja; Mjelle, Robin. (2025) Can circulating microRNAs predict colorectal cancer? Results from a nested case–control study of pre-diagnostic serum samples from two prospective biobanks. BMC Cancer
Academic article

2024

Glærum, Ingvild Lynneberg; Dunville, Keagan; Moan, Kristian Magnus; Krause, Maike; Montaldo, Nicola Pietro; Kirikae, Hinaco; Nigro, Maximiliano Jose; Sætrom, Pål; van Loon, Barbara; Quattrocolo, Giulia. (2024) Postnatal persistence of hippocampal Cajal-Retzius cells has a critical role in the establishment of the hippocampal circuit. Development
Academic article
Bordin, Diana Lilian; Grooms, Kayla Mae; Montaldo, Nicola Pietro; Martin, Sarah Louise Fordyce; Sætrom, Pål; Samson, Leona D.; Bjørås, Magnar; van Loon, Barbara. (2024) Loss of alkyladenine DNA glycosylase alters gene expression in the developing mouse brain and leads to reduced anxiety and improved memory. DNA Repair
Academic article
Fotopoulos, Ioannis; Nguyen, Olav Toai Duc; Nøst, Therese Haugdahl; Markaki, Maria; Lagani, Vincenzo; Mjelle, Robin; Sandanger, Torkjel Manning; Sætrom, Pål; Tsamardinos, Ioannis; Røe, Oluf Dimitri. (2024) Promising microRNAs in pre-diagnostic serum associated with lung cancer up to eight years before diagnosis: a HUNT study. Journal of Cancer Research and Clinical Oncology
Academic article
Potenza, Maria Letizia; Blankvoort, Stefan Matthias Adriaan; Carvalho, Miguel; Grimstvedt, Joachim Schweder; Di Maria, Valentina; Moan, Kristian Magnus; Raveendran Nair, Rajeevkumar; Flatset, Marcus Sandbukt; Zhang, Qiangwei; Thomas, Laurent Francois. (2024) Generation of an enhancer-driven gene expression viral tool specific to dentate granule cell-types through direct hippocampal injection. Frontiers in Neuroscience
Academic article
Sætrom, Pål; Lehvaslaiho, Heikki; Stansberg, Christine; Awan, Haneef; Hesam, Ahmad. (2024) EOSC-ENTRUST D13.4 Year one version of EOSC-ENTRUST Blueprint & Interoperability Framework. zenodo
Professional article
Bugaj, Anna Maria; Kunath, Nicolas; Saasen, Vidar Langseth; Fernández Berrocal, Marion Silvana; Vankova, Ana; Sætrom, Pål; Bjørås, Magnar; Ye, Jing. (2024) Dissecting gene expression networks in the developing hippocampus through the lens of NEIL3 depletion. Progress in Neurobiology
Academic article
Neurauter, Christine Gran; Pannone, Marco; Sousa, Mirta; Wang, Wei; Kusnierczyk, Anna; Luna, Luisa; Sætrom, Pål; Scheffler, Katja; Bjørås, Magnar. (2024) Enhanced glutathione levels confer resistance to apoptotic and ferroptotic programmed cell death in NEIL DNA glycosylase deficient HAP1 cells. Free Radical Biology & Medicine
Academic article

2023

Urbarova, Ilona Halva; Skogholt, Anne Heidi; Sun, Yi-Qian; Mai, Xiao-Mei; Grønberg, Bjørn Henning; Sandanger, Torkjel Manning; Sætrom, Pål; Nøst, Therese Haugdahl. (2023) Increased expression of individual genes in whole blood is associated with late-stage lung cancer at and close to diagnosis. Scientific Reports
Academic article
Rocque, Mariève; Leipart, Vilde; Singh, Ashish Kumar; Mur, Pilar; Olsen, Maren Fridtjofsen; Engebretsen, Lars Fredri; Martin-Ramos, Edgar; Aligué, Rosa; Sætrom, Pål; Valle, Laura. (2023) Characterization of POLE c.1373A > T p.(Tyr458Phe), causing high cancer risk. Molecular Genetics and Genomics
Academic article
Andersson-Rusch, Clara Leticia; Quist-Løkken, Ingrid; Sætrom, Pål; Beisvag, Vidar; Rolinski, Milosz; Aas, Per Arne; van Loon, Barbara; Holien, Toril. (2023) Genome-Wide CRISPR/Cas9 Knock-out Screen Identifies Apoptosis-Relevant Genes in Multiple Myeloma. Blood
Conference abstract
Baiju, Nikita; Rylander, Karin Charlotta Maria; Sætrom, Pål; Sandanger, Torkjel M; Nøst, Therese Haugdahl. (2023) Associations of gene expression in blood with BMI and weight changes among women in the Norwegian Women and Cancer postgenome cohort. Obesity
Academic article
Moholdt, Trine; Ashby, Emily Rose; Tømmerdal, Karina Hammer; Lemoine, Maeliss Cynthia Chloe; Holm, Rebecca Lyng; Sætrom, Pål; Iversen, Ann-Charlotte; Ravi, Anuradha; Simpson, Melanie Rae; Giskeødegård, Guro F.. (2023) Randomised controlled trial of exercise training during lactation on breast milk composition in breastfeeding people with overweight/obesity: a study protocol for the MILKSHAKE trial. BMJ Open sport & exercise medicine
Academic article
Konstantinidis, Ioannis; Sætrom, Pål; Fernandes, Jorge Manuel de Oliveira. (2023) Genome-wide hydroxymethylation profiles in liver of female Nile tilapia with distinct growth performance. Scientific Data
Academic article
Konstantinidis, Ioannis; Sætrom, Pål; Brieuc, Marine Servane Ono; Jakobsen, Kjetill Sigurd; Liedtke, Hannes; Pohlmann, Caroline; Tsoulia, Thomais; Fernandes, Jorge Manuel de Oliveira. (2023) DNA hydroxymethylation differences underlie phenotypic divergence of somatic growth in Nile tilapia reared in common garden. Epigenetics
Academic article
Pettersen, Caroline Hild Hakvåg; Samdal, Helle; Sætrom, Pål; Wibe, Arne; Hermansen, Erland; Schønberg, Svanhild Margrethe Arentz. (2023) The Salmon Oil OmeGo Reduces Viability of Colorectal Cancer Cells and Potentiates the Anti-Cancer Effect of 5-FU. Marine Drugs
Academic article
Lien, Hilde Julie Tokle; Pedersen, Tina Therese; Jakobsen, Bente; Flatberg, Arnar; Chawla, Konika; Sætrom, Pål; Fenstad, Mona H.. (2023) Single-cell resolution of longitudinal blood transcriptome profiles in rheumatoid arthritis, systemic lupus erythematosus and healthy control pregnancies. Annals of the Rheumatic Diseases
Academic article
Olsen, Lene Christin; Galler, Meital; Witter, Menno Peter; Sætrom, Pål; O'Reilly, Kally C. (2023) Transcriptional development of the hippocampus and the dorsal–intermediate–ventral axis in rats. Hippocampus
Academic article
Lefol, Yohan Pierre; Korfage, Tom; Mjelle, Robin; Prebensen, Christian Haugland; Lüders, Torben; Müller, Bruno; Krokan, Hans Einar; Sarno, Antonio; Alsøe, Lene; Berdal, Jan-Erik. (2023) TiSA: TimeSeriesAnalysis - A pipeline for the analysis of longitudinal transcriptomics data. NAR Genomics and Bioinformatics
Academic article

2022

Røe, Oluf Dimitri; Fotopoulos, I; Nguyen, Olav Toai Duc; Nøst, Therese Haugdahl; Markaki, M; Lagani, Vincenzo; Mjelle, Robin; Sandanger, Torkjel M; Sætrom, Pål; Tsamardinos, I. (2022) Common MicroRNAs in Pre-diagnostic Serum Associated with Lung Cancer in Two Cohorts up to Eight Years Before Diagnosis: A HUNT Study. Journal of Thoracic Oncology
Conference abstract
Grapotte, Mathys; Saraswat, Manu; Bessière, Chloé; Menichelli, Christophe; Ramilowski, Jordan A.; Severin, Jessica; Hayashizaki, Yoshihide; Itoh, Masayoshi; Tagami, Michihira; Murata, Mitsuyoshi. (2022) Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network (Nature Communications, (2021), 12, 1, (3297), 10.1038/s41467-021-23143-7). Nature Communications
Corrigendum
Urbarova, Ilona H.; Nøst, Therese Haugdahl; Skogholt, Anne Heidi; Mjelle, Robin; Paulsen, Erna-Elise; Dønnem, Tom; Andersen, Sigve; Markaki, Maria; Røe, Oluf Dimitri; Johansson, Mikael. (2022) Increased Levels of mRNAs and miRNAs Associated with Imminent and Advanced Lung Cancer. Journal of Thoracic Oncology
Conference abstract
Nøst, Therese Haugdahl; Skogholt, Anne Heidi; Urbarova, Ilona Halva; Mjelle, Robin; Paulsen, Erna-Elise; Dønnem, Tom; Andersen, Sigve; Markaki, Maria; Røe, Oluf Dimitri; Johansson, Mikael. (2022) Increased levels of microRNA-320 in blood serum and plasma is associated with imminent and advanced lung cancer. Molecular Oncology
Academic article

2021

Baiju, Nikita; Sandanger, Torkjel M; Sætrom, Pål; Nøst, Therese Haugdahl. (2021) Gene expression in blood reflects smoking exposure among cancer-free women in the Norwegian Women and Cancer (NOWAC) postgenome cohort. Scientific Reports
Academic article
Samdal, Helle; Olsen, Lene Christin; Grøn, Knut Sverre; Røyset, Elin Synnøve; Høiem, Therese Stork; Nervik, Ingunn; Sætrom, Pål; Wibe, Arne; Schønberg, Svanhild Margrethe Arentz; Pettersen, Caroline Hild. (2021) Establishment of a patient-derived xenograft model of colorectal cancer in CIEA NOG mice and exploring smartfish liquid diet as a source of omega-3 fatty acids. Biomedicines
Academic article
Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Hegre, Siv Anita; Danielsen, Kjersti; Jenssen, Marita; Furberg, Anne-Sofie; Saunes, Marit; Hveem, Kristian; Sætrom, Pål. (2021) MicroRNA profiling of psoriatic skin identifies 11 miRNAs associated with disease severity. Experimental Dermatology
Academic article
Hildrestrand, Gunn Annette; Rolseth, Veslemøy; Kunath, Nicolas; Suganthan, Rajikala; Jensen, Vidar; Bugaj, Anna Maria; Berrocal, Marion Silvana Fernandez; SIkko, Sunniva Bøe; Vetlesen, Susanne; Kusnierczyk, Anna. (2021) NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice. Communications Biology
Academic article
Konstantinidis, Ioannis; Anastasiadi, Dafni; Sætrom, Pål; Nedoluzhko, Artem; Mjelle, Robin; Podgorniak, Tomasz; Piferrer, Francesc; Fernandes, Jorge Manuel de Oliveira. (2021) Epigenetic mapping of the somatotropic axis in Nile tilapia reveals differential DNA hydroxymethylation marks associated with growth. Genomics
Academic article
Tingö, Lina; Ahlberg, Emelie; Johansson, Lovisa; Pedersen, Sindre Andre; Chawla, Konika; Sætrom, Pål; Cione, Erika; Simpson, Melanie Rae. (2021) Non-coding RNAs in human breast milk: A systematic review. Frontiers in Immunology
Academic literature review
Rolinski, Milosz; Montaldo, Nicola Pietro; Aksu, Merdane Ezgi; Martin, Sarah Fordyce; Brambilla, Alessandro; Kunath, Nicolas; Johansen, Jostein; Erlandsen, Sten Even; Liabakk, Nina-Beate; Rian, Kristin. (2021) Loss of Mediator complex subunit 13 (MED13) promotes resistance to alkylation through cyclin D1 upregulation. Nucleic Acids Research (NAR)
Academic article
Hegre, Siv Anita; Samdal, Helle; Klima, Antonin; Stovner, Endre Bakken; Nørsett, Kristin Gabestad; Liabakk, Nina-Beate; Olsen, Lene Christin; Chawla, Konika; Aas, Per Arne; Sætrom, Pål. (2021) Joint changes in RNA, RNA polymerase II, and promoter activity through the cell cycle identify non-coding RNAs involved in proliferation. Scientific Reports
Academic article

2020

Mjelle, Robin; Aass, Kristin Roseth; Sjursen, Wenche; Hofsli, Eva; Sætrom, Pål. (2020) sMETASeq: combined profiling of microbiota and host small RNAs. iScience
Academic article
Huang, Kai-Wen; Reebye, Vikash; Czysz, Katherine; Ciriello, Simona; Dorman, Stephanie; Reccia, Isabella; Lai, Hong-Shiee; Peng, Ling; Kostomitsopoulos, Nikos; Nicholls, Joanna. (2020) Liver Activation of Hepatocellular Nuclear Factor-4α by Small Activating RNA Rescues Dyslipidemia and Improves Metabolic Profile. Molecular Therapy Nucleic Acids
Academic article
Sarker, Debashis; Plummer, Ruth; Meyer, Tim; Sodergren, Mikael H; Basu, Bristi; Chee, Cheng Ean; Huang, Kai-Wen; Palmer, Daniel H; Ma, Yuk Ting; Evans, T R Jeff. (2020) MTL-CEBPA, a Small Activating RNA Therapeutic Upregulating C/EBP-α, in Patients with Advanced Liver Cancer: A First-in-Human, Multicenter, Open-Label, Phase I Trial. Clinical Cancer Research
Academic article
Konstantinidis, Ioannis; Sætrom, Pål; Mjelle, Robin; Nedoluzhko, Artem; Robledo, Diego; Fernandes, Jorge Manuel de Oliveira. (2020) Major gene expression changes and epigenetic remodelling in Nile tilapia muscle after just one generation of domestication. Epigenetics
Academic article

2019

Stovner, Endre Bakken; Sætrom, Pål. (2019) epic2 efficiently finds diffuse domains in ChIP-seq data. Bioinformatics
Academic article
Brian, Ben F; Jolicoeur, Adrienne S; Guerrero, Candace R.; Nunez, Myra G; Sychev, Zoi E; Hegre, Siv Anita; Sætrom, Pål; Habib, Nagy; Drake, Justin M; Schwertfeger, Kathryn L. (2019) Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells. eLIFE
Academic article
Zhao, Xiaoyang; Reebye, Vikash; Hitchen, Paul; Fan, Jia; Jiang, Hongchi; Sætrom, Pål; Rossi, John; Habib, Nagy A; Huang, Kai-Wen. (2019) Mechanisms involved in the activation of C/EBP? by small activating RNA in hepatocellular carcinoma. Oncogene
Academic article
Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Danielsen, Kjersti; Jenssen, Marita; Furberg, Anne-Sofie; Saunes, Marit; Hveem, Kristian; Sætrom, Pål; Løset, Mari. (2019) Combined mRNA and miRNA Analysis of Psoriatic Skin. Forum for Nordic Dermato-Venereology
Conference abstract
Mjelle, Robin; Sjursen, Wenche; Thommesen, Liv; Sætrom, Pål; Hofsli, Eva. (2019) Small RNA expression from viruses, bacteria and human miRNAs in colon cancer tissue and its association with microsatellite instability and tumor location. BMC Cancer
Academic article
Kroustallaki, Pinelopi; Lirussi, Lisa; Carracedo Huroz, Sergio; You, Panpan; Esbensen, Qin Ying; Götz, Alexandra; Jobert, Laure; Alsøe, Lene; Sætrom, Pål; Gagos, Sarantis. (2019) SMUG1 Promotes Telomere Maintenance through Telomerase RNA Processing. Cell reports
Academic article
Stovner, Endre Bakken; Sætrom, Pål. (2019) PyRanges: efficient comparison of genomic intervals in Python. Bioinformatics
Academic article
Larose, Tricia L; Sætrom, Pål; Martinussen, Marit; Skogseth, Haakon; Sandanger, Torkjel M; Scélo, Ghislaine; McHale, Cliona M.; Jacobsen, Geir Wenberg; Smith, Martyn T.. (2019) In utero exposure to endocrine disrupting chemicals, micro-RNA profiles, and fetal growth: a pilot study protocol. Journal of Public Health Research
Academic article
Mjelle, Robin; Dima, Simona O; Bacalbasa, Nicolae; Chawla, Konika; Sorop, Andrei; Cucu, Dana; Herlea, Vlad; Sætrom, Pål; Popescu, Irinel. (2019) Comprehensive transcriptomic analyses of tissue, serum, and serum exosomes from hepatocellular carcinoma patients. BMC Cancer
Academic article
Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Danielsen, Kjersti; Jenssen, Marita; Furberg, Anne-Sofie; Saunes, Marit; Hveem, Kristian; Sætrom, Pål; Løset, Mari. (2019) Differentially Expressed miRNAs and mRNAs in Psoriatic Skin. Journal of Investigative Dermatology
Conference abstract
Montaldo, Nicola Pietro; Bordin, Diana Lilian; Brambilla, Alessandro; Rösinger, Marcel; Martin, Sarah Fordyce; Bjørås, Karine Øian; Bradamante, Stefano; Aas, Per Arne; Furrer, Antonia; Olsen, Lene Christin. (2019) Alkyladenine DNA glycosylase associates with transcription elongation to coordinate DNA repair with gene expression. Nature Communications
Academic article

2018

Reebye, Vikash; Huang, Kai-Wen; Lin, Vivian; Jarvis, Sheba; Cutilas, Pedro; Dorman, Stephanie; Ciriello, Simona; Andrikakou, Pinelopi; Voutila, Jon; Sætrom, Pål. (2018) Gene activation of CEBPA using saRNA: Preclinical studies of the first in human saRNA drug candidate for liver cancer. Oncogene
Academic article
Sarno, Antonio; Sætrom, Pål; Kavli, Bodil Merete; Pettersen, Henrik Sahlin. (2018) Genomic Uracil and Cancer.
Non-fiction chapter

2017

Skogholt, Anne Heidi; Ryeng, Einar; Erlandsen, Sten Even; Skorpen, Frank; Schønberg, Svanhild Margrethe Arentz; Sætrom, Pål. (2017) Gene expression differences between PAXgene and Tempus blood RNA tubes are highly reproducible between independent samples and biobanks. BMC Research Notes
Academic article
rie, D de; Abugesaissa, I; Alam, T; Arner, E; Ashoor, H; Åström, G; Babina, M; Bertin, N; Burroughs, AM; Carlisle, AJ. (2017) An integrated expression atlas of miRNAs and their promoters in human and mouse. Nature Biotechnology
Academic article
Mjelle, Robin; Sellæg, Kjersti; Sætrom, Pål; Thommesen, Liv; Sjursen, Wenche; Hofsli, Eva. (2017) Identification of metastasis-associated microRNAs in serum from rectal cancer patients. OncoTarget
Academic article
Olsen, Lene Christin; O'Reilly, Kally; Liabakk, Nina-Beate; Witter, Menno; Sætrom, Pål. (2017) MicroRNAs contribute to postnatal development of laminar differences and neuronal subtypes in the rat medial entorhinal cortex. Brain Structure and Function
Academic article
Olsen, Maria Belland; Hildrestrand, Gunn Annette; Scheffler, Katja; Vinge, Leif Erik; Alfsnes, Katrine; Palibrk, Vuk; Wang, Junbai; Neurauter, Christine Gran; Gomez, Luisa Fernanda Luna; Johansen, Jostein. (2017) NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture. Cell reports
Academic article
Landfors, Miriam; Johansen, Jostein; Aronsen, Jan Magnus; Vågbø, Cathrine Broberg; Doré, Louis C.; He, Chuan; Sjaastad, Ivar; Sætrom, Pål; Fedorcsák, Péter; Dahl, John Arne. (2017) Genome-wide profiling of DNA 5-hydroxymethylcytosine during rat Sertoli cell maturation. Cell Discovery
Academic article
Voutila, Jon; Reebye, Vikash; Roberts, Thomas C.; Protopapa, Pantelitsa; Andrikakou, Pinelopi; Blakey, David C.; Habib, Robert; Huber, Hans; Sætrom, Pål; Rossi, John J.. (2017) Development and mechanism of small activating RNA targeting CEBPA, a novel therapeutic in clinical trials for liver cancer. Molecular Therapy
Academic article

2016

Stracquadanio, Giovanni; Wang, Xuting; Wallace, Marsha D; Grawenda, Anna M.; Zhang, Ping; Hewitt, Juliet; Zeron-Medina, Jorge; Castro-Giner, Francesc; Tomlinson, Ian P; Goding, Colin R.. (2016) The importance of p53 pathway genetics in inherited and somatic cancer genomes. Nature Reviews Cancer
Academic article
Robles, Ana I.; Olsen, Karina Standahl; Tsui, Dana W.T.; Georgoulias, Vassilis; Creaney, Jenette; Dobra, Katalin; Vyberg, Mogens; Minato, Nagahiro; Anders, Robert A.; Børresen-Dale, Anne-Lise. (2016) Excerpts from the 1st international NTNU symposium on current and future clinical biomarkers of cancer: innovation and implementation, June 16th and 17th 2016, Trondheim, Norway. Journal of Translational Medicine
Academic article
Røe, Oluf Dimitri; Mjelle, Robin; Sætrom, Pål; Andreassen, Trygve; Bathen, Tone Frost; Hveem, Kristian. (2016) Serum microRNAs/enriched pathways in lung cancer 1-4 years before diagnosis: A pilot study from the HUNT Biobank, Norway. Journal of Clinical Oncology
Conference abstract
Langkilde, Ane; Olsen, Lene Christin; Sætrom, Pål; Drabløs, Finn Sverre; Besenbacher, Søren; Raaby, Line; Johansen, Claus; Iversen, Lars. (2016) Pathway Analysis of Skin from Psoriasis Patients after Adalimumab Treatment Reveals New Early Events in the Anti-Inflammatory Mechanism of Anti-TNF-α. PLOS ONE
Academic article
Yoon, Sorah; Huang, Kai-Wen; Reebye, Vikash; Mintz, Paul; Tien, Yu-Wen; Lai, Hong-Shiee; Sætrom, Pål; Reccia, Isabella; Swiderski, Piotr; Armstrong, Brian. (2016) Targeted Delivery of C/EBPα -saRNA by Pancreatic Ductal Adenocarcinoma-specific RNA Aptamers Inhibits Tumor Growth in Vivo. Molecular Therapy
Academic article

2015

Hansen, Maren Fridtjofsen; Johansen, Jostein; Bjørnevoll, Inga; Sylvander, Anna Elisabeth; Steinsbekk, Kristin Solum; Sætrom, Pål; Sandvik, Arne Kristian; Drabløs, Finn; Sjursen, Wenche. (2015) A novel POLE mutation associated with cancers of colon, pancreas, ovaries and small intestine. Familial Cancer
Academic article
Hansen, Maren Fridtjofsen; Johansen, Jostein; Bjørnevoll, Inga; Sylvander, Anna Elisabeth; Steinsbekk, Kristin Solum; Sætrom, Pål; Sandvik, Arne Kristian; Drabløs, Finn; Sjursen, Wenche. (2015) A novel POLE variant, identified by exome sequencing, causes colorectal- and extra-colonic cancers. Familial Cancer
Conference abstract
Mjelle, Robin; Hegre, Siv Anita; Aas, Per Arne; Slupphaug, Geir; Drabløs, Finn; Sætrom, Pål; Krokan, Hans Einar. (2015) Cell cycle regulation of human DNA repair and chromatin remodeling genes. DNA Repair
Academic article
Achar, Avinash; Sætrom, Pål. (2015) RNA motif discovery: a computational overview. Biology Direct
Academic literature review
Pettersen, Henrik Sahlin; Galashevskaya, Anastasia; Doseth, Berit; Sousa, Mirta; Sarno, Antonio; Visnes, Torkild; Aas, Per Arne; Liabakk, Nina-Beate; Slupphaug, Geir; Sætrom, Pål. (2015) AID expression in B-cell lymphomas causes accumulation of genomic uracil and a distinct AID mutational signature. DNA Repair
Academic article
Simpson, Melanie Rae; Brede, Gaute; Johansen, Jostein; Johnsen, Roar; Storrø, Ola; Sætrom, Pål; Øien, Torbjørn. (2015) Human breast milk miRNA, maternal probiotic supplementation and atopic dermatitis in offspring. PLOS ONE
Academic article

2014

Reebye, V; Sætrom, Pål; Mintz, PJ; Huang, KW; Swiderski, P; Peng, L; Liu, C; Liu, XX; Lindkaer-Jensen, S; Zacharoulis, D. (2014) A Novel RNA Oligonucleotide Improves Liver Function and Inhibits Liver Carcinogenesis In Vivo. Hepatology
Academic article
Mintz, PJ; Huang, KW; Reebye, V; Nteliopoulos, G; Lai, HS; Sætrom, Pål; Kasahara, N; Jensen, S; Pai, M; Gordon, MYA. (2014) Exploiting Human CD34(+) Stem Cell-conditioned Medium for Tissue Repair. Molecular Therapy
Academic article
Krokan, Hans Einar; Sætrom, Pål; Aas, Per Arne; Pettersen, Henrik P Sahlin; Kavli, Bodil Merete; Slupphaug, Geir. (2014) Error-free versus mutagenic processing of genomic uracil-Relevance to cancer. DNA Repair
Academic article
Lange, LA; Hu, Y; Zhang, H; Xue, C; Schmidt, EM; Tang, ZZ; Bizon, C; Lange, EM; Smith, JD; Turner, EH. (2014) Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol. American Journal of Human Genetics
Academic article
Reddy, MA; Chen, Z; Park, JT; Wang, M; Lanting, L; Zhang, Q; Bhatt, K; Leung, A; Wu, X; Putta, S. (2014) Regulation of inflammatory phenotype in macrophages by a diabetes-induced long noncoding RNA. Diabetes
Academic article
Razick, Sabry; Mocnik, Rok; Thomas, Laurent; Ryeng, Einar; Drabløs, Finn; Sætrom, Pål. (2014) The eGenVar data management system--cataloguing and sharing sensitive data and metadata for the life sciences. Database: The Journal of Biological Databases and Curation
Academic article
Thomas, Laurent; Sætrom, Pål. (2014) Circular RNAs are depleted of polymorphisms at microRNA binding sites. Bioinformatics
Academic article

2013

Diaz, Javier Pena; Hegre, Siv Anita; Anderssen, Endre; Aas, Per Arne; Mjelle, Robin; Gilfillan, Gregor Duncan; Lyle, Robert; Drabløs, Finn; Krokan, Hans Einar; Sætrom, Pål. (2013) Transcription profiling during the cell cycle shows that a subset of Polycomb-targeted genes is upregulated during DNA replication. Nucleic Acids Research (NAR)
Academic article
Hegre, Siv Anita; Sætrom, Pål; Aas, Per Arne; Pettersen, Henrik P Sahlin; Otterlei, Marit; Krokan, Hans Einar. (2013) Multiple microRNAs may regulate DNA repair enzyme uracil‐DNA glycosylase. DNA Repair
Academic article
Sætrom, Pål. (2013) Designing dual-targeting siRNA duplexes having two active strands that combine siRNA and microRNA-like targeting. Methods in molecular biology
Academic article
Leung, A; Trac, C; Jin, W; Lanting, L; Akbany, A; Sætrom, Pål; Schones, DE; Natarajan, R. (2013) Novel Long Noncoding RNAs Are Regulated by Angiotensin II in Vascular Smooth Muscle Cells. Circulation Research
Academic article
Chavali, Sreenivas; Bruhn, Sören; Tiemann, Katrin; Sætrom, Pål; Barrenäs, Fredrik; Saito, Takaya; Kanduri, Kartiek; Wang, Hui; Benson, Mikael. (2013) MicroRNAs act complementarily to regulate disease-related mRNA modules in human diseases. RNA: A publication of the RNA Society
Academic article
Lundbæk, Marie B; Sætrom, Pål. (2013) RNAi Screening and Assays.
Academic chapter
Reebye, Vikash; Sætrom, Pål; Mintz, Paul J; Rossi, JJ; Kasahara, Noriyuki; Nteliopoulos, G; Nicholls, Joanna P; Haoudi, Abdelali; Gordon, Myrtle YA; Habib, Nagy A. (2013) A short-activating RNA oligonucleotide targeting the islet β-cell transcriptional factor MafA in CD34(+) cells. Molecular Therapy Nucleic Acids
Academic article

2012

Mintz, Paul J; Sætrom, Pål; Reebye, Vikash; Lundbæk, Marie Benner; Lao, Kaiqin; Rossi, John J; Gaensler, Karin ML; Kasahara, Noriyuki; Nicholls, Joanna P; Jensen, Steen. (2012) MicroRNA-181a* Targets Nanog in a Subpopulation of CD34+ Cells Isolated From Peripheral Blood. Molecular Therapy Nucleic Acids
Academic article
Saito, Takaya; Sætrom, Pål. (2012) Target gene expression levels and competition between transfected and endogenous microRNAs are strong confounding factors in microRNA high-throughput experiments. Silence
Academic article
Håndstad, Tony; Rye, Morten Beck; Mocnik, Rok; Drabløs, Finn; Sætrom, Pål. (2012) Cell-type specificity of ChIP-predicted transcription factor binding sites. BMC Genomics
Academic article
Voutila, J; Sætrom, Pål; Mintz, Paul J; Sun, Guihua; Alluin, Jessica; Rossi, JJ; Habib, Nagy A.; Kasahara, N.. (2012) Gene expression profile changes after short-activating RNA-mediated induction of endogenous pluripotency factors in human mesenchymal stem cells. Molecular Therapy Nucleic Acids
Academic article
Sjögren, A.-K.M.; Barrenäs, Fredrik; Muraro, Antonella; Gustafsson, M; Sætrom, Pål; Wang, H; Benson, M.. (2012) Monozygotic twins discordant for intermittent allergic rhinitis differ in mRNA and protein levels. Allergy. European Journal of Allergy and Clinical Immunology
Academic article
Thomas, Laurent; Sætrom, Pål. (2012) Single Nucleotide Polymorphisms Can Create Alternative Polyadenylation Signals and Affect Gene Expression through Loss of MicroRNA-Regulation. PLoS Computational Biology
Academic article

2011

Thomas, Laurent; Saito, Takaya; Sætrom, Pål. (2011) Inferring causative variants in microRNA target sites. Nucleic Acids Research (NAR)
Academic article
Rye, Morten Beck; Sætrom, Pål; Håndstad, Tony; Drabløs, Finn. (2011) Clustered ChIP-Seq-defined transcription factor binding sites and histone modifications map distinct classes of regulatory elements. BMC Biology
Academic article
Håndstad, Tony; Rye, Morten Beck; Drabløs, Finn; Sætrom, Pål. (2011) A ChIP-Seq Benchmark Shows That Sequence Conservation Mainly Improves Detection of Strong Transcription Factor Binding Sites. PLOS ONE
Academic article
Rye, Morten Beck; Sætrom, Pål; Drabløs, Finn. (2011) A manually curated ChIP-seq benchmark demonstrates room for improvement in current peak-finder programs. Nucleic Acids Research (NAR)
Academic article
Lundbæk, Marie Benner; Sætrom, Pål. (2011) Unconventional RNA interference – recent approaches to robust RNAi. European Pharmaceutical Review
Professional article

2010

Matveeva, OV; Kang, YB; Spiridonov, AN; Sætrom, Pål; Nemtsov, VA; Ogurtsov, AY; Nechipurenko, YD; Shabalina, SA. (2010) Optimization of Duplex Stability and Terminal Asymmetry for shRNA Design. PLOS ONE
Academic article
Tiemann, Katrin; Höhn, Britta; Ehsani, Ali; Forman, Stephen J.; Rossi, John J.; Sætrom, Pål. (2010) Dual-targeting siRNAs. RNA: A publication of the RNA Society
Academic article
Saito, Takaya; Sætrom, Pål. (2010) MicroRNAs – targeting and target prediction. New Biotechnology
Academic literature review
Saito, Takaya; Sætrom, Pål. (2010) A two-step site and mRNA-level model for predicting microRNA targets. BMC Bioinformatics
Academic article
Ehsani, A; Sætrom, Pål; Zhang, J; Alluin, J; Li, HT; Snøve, Ola; Aagaard, L; Rossi, JJ. (2010) Rational Design of Micro-RNA-like Bifunctional siRNAs Targeting HIV and the HIV Coreceptor CCR5. Molecular Therapy
Academic article

2009

Sætrom, Pål; Klein, Joern. (2009) miRNA and viral infections in vertebrates. European Pharmaceutical Review
Academic literature review
Snøve, Ola; Sætrom, Pål. (2009) Animal MicroRNA gene prediction.
Academic chapter
Sætrom, Pål; Biesinger, Jacob; Li, Sierra M.; Smith, David; Thomas, Laurent Francois; Majzoub, Karim; Rivas, Guillermo E.; Alluin, Jessica; Rossi, John J.; Krontiris, Theodore G.. (2009) A Risk Variant in an miR-125b Binding Site in BMPR1B Is Associated with Breast Cancer Pathogenesis. Cancer Research
Academic article

2008

Lee, N.S.; Kim, J.S.; Cho, W.J.; Lee, M.R.; Steiner, R.; Gompers, A.; Ling, D.; Zhang, J.; Sætrom, Pål; Behlke, Mark A.. (2008) miR-302b maintains "stemness" of human embryonal carcinoma cells by post-transcriptional regulation of Cyclin D2 expression. Biochemical and Biophysical Research Communications - BBRC
Academic article
Smith, DD; Sætrom, Pål; Snøve, Ola; Lundberg, C; Rivas, GE; Glackin, C; Larson, GP. (2008) Meta-analysis of breast cancer microarray studies in conjunction with conserved cis-elements suggest patterns for coordinate regulation. BMC Bioinformatics
Academic article
Kim, Daniel H.; S�trom, P�l; Sn�ve, Ola; Rossi, John J.. (2008) MicroRNA-directed transcriptional gene silencing in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Academic article
Aagaard, Lars; Zhang, J; Eije, K J von; Li, H; Saetrom, P; S�trom, P�l; Amarzguioui, M; Rossi, John J.. (2008) Engineering and optimization of the miR-106b cluster for ectopic expression of multiplexed anti-HIV RNAs. Gene Therapy
Academic article
Soifer, Harris S.; Sano, Masayuki; Sakurai, Kumi; Chomchan, Pritsana; S�trom, P�l; Sherman, Mark A.; Collingwood, Michael A.; Behlke, Mark A.; Rossi, John J.. (2008) A role for the Dicer helicase domain in the processing of thermodynamically unstable hairpin RNAs. Nucleic Acids Research (NAR)
Academic article

2007

Soifer, Harris S.; Rossi, John J.; Sætrom, Pål. (2007) MicroRNAs in Disease and Potential Therapeutic Applications. Molecular Therapy
Academic literature review
Matveeva, Olga; Nechipurenko, Yury; Rossi, Leo; Moore, Barry; Sætrom, Pål; Ogurtsov, Aleksey Y.; Atkins, John F.; Shabalina, Svetlana A.. (2007) Comparison of approaches for rational siRNA design leading to a new efficient and transparent method. Nucleic Acids Research (NAR)
Academic article
Sætrom, Pål; Heale, Bret S.; Snøve, Ola; Aagaard, Lars; Alluin, Jessica; Rossi, John J.. (2007) Distance constraints between microRNA target sites dictate efficacy and cooperativity. Nucleic Acids Research (NAR)
Academic article
Håndstad, Tony; Hestnes, Arne Johan Husebø; Sætrom, Pål. (2007) Motif kernel generated by genetic programming improves remote homology and fold detection. BMC Bioinformatics
Academic article
Sætrom, Pål; Snøve, Ola; Rossi, John J.. (2007) Epigenetics and MicroRNAs. Pediatric Research
Academic literature review
Sætrom, Pål; Snøve, Ola. (2007) Machine learning predicts microRNA target sites.
Academic chapter
Helvik, Snorre Andreas; Snøve, Ola; Sætrom, Pål. (2007) Reliable prediction of Drosha processing sites improves microRNA gene prediction. Bioinformatics
Academic article
Eije, KJ Von; Aagaard, Lars; Sætrom, Pål; Amarzguioui, M; Li, HT; Rossi, JJ. (2007) Prevention of HIV-1 viral escape upon RNAi treatment: Expression systems that generate multiple anti-HIV siRNAs. Human Gene Therapy
Conference abstract
Sætrom, Pål; Snøve, Ola. (2007) Robust machine learning algorithms predict microRNA genes and targets. Methods in Enzymology
Academic article
Sætrom, Pål; Birkeland, Olaf René; Snøve, Ola. (2007) Boosting Improves Stability and Accuracy of Genetic Programming in Biological Sequence Classification.
Academic chapter

2006

Snøve, Ola; Sætrom, Pål. (2006) Nobelpris for RNA-interferens. Tidsskrift for Den norske legeforening (Tidsskriftet)
Editorial
Birkeland, Olaf René; Snøve, Ola; Halaas, Arne; Nedland, Magnar; Sætrom, Pål. (2006) The petacomp Machine - A MIMD Cluster for parallel pattern-mining. Proceedings IEEE International Conference on Cluster Computing
Academic article
Helvik, Snorre Andreas; Snøve, Ola; Sætrom, Pål. (2006) Reliable prediction of Drosha processing sites improves microRNA gene prediction. Bioinformatics
Academic article

2005

Sætrom, Pål. (2005) Hardware accelerated genetic programming for pattern mining in strings. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Sætrom, Pål. (2005) Hardware accelerated genetic programming for pattern mining in strings. NTNU-Trykk
Doctoral thesis

Journal publications

Stahl, Margrethe Cecilie; Bergendahl, K.G.; Zaytseva-Zotova, Daria; Rytterager, K.R.; Nordgård, Catherine Taylor; Kjesbu, Joachim Sebastian; Haslene-Hox, Hanne; Halaas, Øyvind; Sætrom, P.; Chahal, Aman Singh. (2026) RGD-Alginate beads as scaffolds for culturing primary human dermal and pulmonary fibroblasts. Carbohydrate Polymers
Academic article
Lien, Hilde Julie Tokle; Pedersen, Tina Therese; Jakobsen, Bente; Flatberg, Arnar; Leirvik, Gunnhild Vatne; Haug, Markus; Fenstad, Mona H.; Sætrom, Pål. (2025) Single-Cell RNA sequencing of pregnant women with SPRA and SLE: Uncovering cell-independent IFN signatures in SLE and a key role of MAIT and CD4 T-cells in SPRA. Frontiers in Lupus
Conference abstract
Soifer, Harris S.; Rossi, John J.; Sætrom, Pål. (2007) MicroRNAs in Disease and Potential Therapeutic Applications. Molecular Therapy
Academic literature review
Stovner, Endre Bakken; Sætrom, Pål. (2019) epic2 efficiently finds diffuse domains in ChIP-seq data. Bioinformatics
Academic article
Glærum, Ingvild Lynneberg; Dunville, Keagan; Moan, Kristian Magnus; Krause, Maike; Montaldo, Nicola Pietro; Kirikae, Hinaco; Nigro, Maximiliano Jose; Sætrom, Pål; van Loon, Barbara; Quattrocolo, Giulia. (2024) Postnatal persistence of hippocampal Cajal-Retzius cells has a critical role in the establishment of the hippocampal circuit. Development
Academic article
Urbarova, Ilona Halva; Skogholt, Anne Heidi; Sun, Yi-Qian; Mai, Xiao-Mei; Grønberg, Bjørn Henning; Sandanger, Torkjel Manning; Sætrom, Pål; Nøst, Therese Haugdahl. (2023) Increased expression of individual genes in whole blood is associated with late-stage lung cancer at and close to diagnosis. Scientific Reports
Academic article
Baiju, Nikita; Sandanger, Torkjel M; Sætrom, Pål; Nøst, Therese Haugdahl. (2021) Gene expression in blood reflects smoking exposure among cancer-free women in the Norwegian Women and Cancer (NOWAC) postgenome cohort. Scientific Reports
Academic article
Sætrom, Pål; Klein, Joern. (2009) miRNA and viral infections in vertebrates. European Pharmaceutical Review
Academic literature review
Rocque, Mariève; Leipart, Vilde; Singh, Ashish Kumar; Mur, Pilar; Olsen, Maren Fridtjofsen; Engebretsen, Lars Fredri; Martin-Ramos, Edgar; Aligué, Rosa; Sætrom, Pål; Valle, Laura. (2023) Characterization of POLE c.1373A > T p.(Tyr458Phe), causing high cancer risk. Molecular Genetics and Genomics
Academic article
Brian, Ben F; Jolicoeur, Adrienne S; Guerrero, Candace R.; Nunez, Myra G; Sychev, Zoi E; Hegre, Siv Anita; Sætrom, Pål; Habib, Nagy; Drake, Justin M; Schwertfeger, Kathryn L. (2019) Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells. eLIFE
Academic article
Diaz, Javier Pena; Hegre, Siv Anita; Anderssen, Endre; Aas, Per Arne; Mjelle, Robin; Gilfillan, Gregor Duncan; Lyle, Robert; Drabløs, Finn; Krokan, Hans Einar; Sætrom, Pål. (2013) Transcription profiling during the cell cycle shows that a subset of Polycomb-targeted genes is upregulated during DNA replication. Nucleic Acids Research (NAR)
Academic article
Andersson-Rusch, Clara Leticia; Quist-Løkken, Ingrid; Sætrom, Pål; Beisvag, Vidar; Rolinski, Milosz; Aas, Per Arne; van Loon, Barbara; Holien, Toril. (2023) Genome-Wide CRISPR/Cas9 Knock-out Screen Identifies Apoptosis-Relevant Genes in Multiple Myeloma. Blood
Conference abstract
Skogholt, Anne Heidi; Ryeng, Einar; Erlandsen, Sten Even; Skorpen, Frank; Schønberg, Svanhild Margrethe Arentz; Sætrom, Pål. (2017) Gene expression differences between PAXgene and Tempus blood RNA tubes are highly reproducible between independent samples and biobanks. BMC Research Notes
Academic article
Zhao, Xiaoyang; Reebye, Vikash; Hitchen, Paul; Fan, Jia; Jiang, Hongchi; Sætrom, Pål; Rossi, John; Habib, Nagy A; Huang, Kai-Wen. (2019) Mechanisms involved in the activation of C/EBP? by small activating RNA in hepatocellular carcinoma. Oncogene
Academic article
Reebye, Vikash; Huang, Kai-Wen; Lin, Vivian; Jarvis, Sheba; Cutilas, Pedro; Dorman, Stephanie; Ciriello, Simona; Andrikakou, Pinelopi; Voutila, Jon; Sætrom, Pål. (2018) Gene activation of CEBPA using saRNA: Preclinical studies of the first in human saRNA drug candidate for liver cancer. Oncogene
Academic article
Hegre, Siv Anita; Sætrom, Pål; Aas, Per Arne; Pettersen, Henrik P Sahlin; Otterlei, Marit; Krokan, Hans Einar. (2013) Multiple microRNAs may regulate DNA repair enzyme uracil‐DNA glycosylase. DNA Repair
Academic article
Thomas, Laurent; Saito, Takaya; Sætrom, Pål. (2011) Inferring causative variants in microRNA target sites. Nucleic Acids Research (NAR)
Academic article
Mintz, Paul J; Sætrom, Pål; Reebye, Vikash; Lundbæk, Marie Benner; Lao, Kaiqin; Rossi, John J; Gaensler, Karin ML; Kasahara, Noriyuki; Nicholls, Joanna P; Jensen, Steen. (2012) MicroRNA-181a* Targets Nanog in a Subpopulation of CD34+ Cells Isolated From Peripheral Blood. Molecular Therapy Nucleic Acids
Academic article
Reebye, V; Sætrom, Pål; Mintz, PJ; Huang, KW; Swiderski, P; Peng, L; Liu, C; Liu, XX; Lindkaer-Jensen, S; Zacharoulis, D. (2014) A Novel RNA Oligonucleotide Improves Liver Function and Inhibits Liver Carcinogenesis In Vivo. Hepatology
Academic article
Baiju, Nikita; Rylander, Karin Charlotta Maria; Sætrom, Pål; Sandanger, Torkjel M; Nøst, Therese Haugdahl. (2023) Associations of gene expression in blood with BMI and weight changes among women in the Norwegian Women and Cancer postgenome cohort. Obesity
Academic article
Mintz, PJ; Huang, KW; Reebye, V; Nteliopoulos, G; Lai, HS; Sætrom, Pål; Kasahara, N; Jensen, S; Pai, M; Gordon, MYA. (2014) Exploiting Human CD34(+) Stem Cell-conditioned Medium for Tissue Repair. Molecular Therapy
Academic article
Samdal, Helle; Olsen, Lene Christin; Grøn, Knut Sverre; Røyset, Elin Synnøve; Høiem, Therese Stork; Nervik, Ingunn; Sætrom, Pål; Wibe, Arne; Schønberg, Svanhild Margrethe Arentz; Pettersen, Caroline Hild. (2021) Establishment of a patient-derived xenograft model of colorectal cancer in CIEA NOG mice and exploring smartfish liquid diet as a source of omega-3 fatty acids. Biomedicines
Academic article
Moholdt, Trine; Ashby, Emily Rose; Tømmerdal, Karina Hammer; Lemoine, Maeliss Cynthia Chloe; Holm, Rebecca Lyng; Sætrom, Pål; Iversen, Ann-Charlotte; Ravi, Anuradha; Simpson, Melanie Rae; Giskeødegård, Guro F.. (2023) Randomised controlled trial of exercise training during lactation on breast milk composition in breastfeeding people with overweight/obesity: a study protocol for the MILKSHAKE trial. BMJ Open sport & exercise medicine
Academic article
Konstantinidis, Ioannis; Sætrom, Pål; Fernandes, Jorge Manuel de Oliveira. (2023) Genome-wide hydroxymethylation profiles in liver of female Nile tilapia with distinct growth performance. Scientific Data
Academic article
Hansen, Maren Fridtjofsen; Johansen, Jostein; Bjørnevoll, Inga; Sylvander, Anna Elisabeth; Steinsbekk, Kristin Solum; Sætrom, Pål; Sandvik, Arne Kristian; Drabløs, Finn; Sjursen, Wenche. (2015) A novel POLE mutation associated with cancers of colon, pancreas, ovaries and small intestine. Familial Cancer
Academic article
Hansen, Maren Fridtjofsen; Johansen, Jostein; Bjørnevoll, Inga; Sylvander, Anna Elisabeth; Steinsbekk, Kristin Solum; Sætrom, Pål; Sandvik, Arne Kristian; Drabløs, Finn; Sjursen, Wenche. (2015) A novel POLE variant, identified by exome sequencing, causes colorectal- and extra-colonic cancers. Familial Cancer
Conference abstract
Matveeva, Olga; Nechipurenko, Yury; Rossi, Leo; Moore, Barry; Sætrom, Pål; Ogurtsov, Aleksey Y.; Atkins, John F.; Shabalina, Svetlana A.. (2007) Comparison of approaches for rational siRNA design leading to a new efficient and transparent method. Nucleic Acids Research (NAR)
Academic article
Sætrom, Pål; Heale, Bret S.; Snøve, Ola; Aagaard, Lars; Alluin, Jessica; Rossi, John J.. (2007) Distance constraints between microRNA target sites dictate efficacy and cooperativity. Nucleic Acids Research (NAR)
Academic article
Håndstad, Tony; Hestnes, Arne Johan Husebø; Sætrom, Pål. (2007) Motif kernel generated by genetic programming improves remote homology and fold detection. BMC Bioinformatics
Academic article
Sætrom, Pål; Snøve, Ola; Rossi, John J.. (2007) Epigenetics and MicroRNAs. Pediatric Research
Academic literature review
Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Danielsen, Kjersti; Jenssen, Marita; Furberg, Anne-Sofie; Saunes, Marit; Hveem, Kristian; Sætrom, Pål; Løset, Mari. (2019) Combined mRNA and miRNA Analysis of Psoriatic Skin. Forum for Nordic Dermato-Venereology
Conference abstract
Mjelle, Robin; Sjursen, Wenche; Thommesen, Liv; Sætrom, Pål; Hofsli, Eva. (2019) Small RNA expression from viruses, bacteria and human miRNAs in colon cancer tissue and its association with microsatellite instability and tumor location. BMC Cancer
Academic article
Mjelle, Robin; Hegre, Siv Anita; Aas, Per Arne; Slupphaug, Geir; Drabløs, Finn; Sætrom, Pål; Krokan, Hans Einar. (2015) Cell cycle regulation of human DNA repair and chromatin remodeling genes. DNA Repair
Academic article
Konstantinidis, Ioannis; Sætrom, Pål; Brieuc, Marine Servane Ono; Jakobsen, Kjetill Sigurd; Liedtke, Hannes; Pohlmann, Caroline; Tsoulia, Thomais; Fernandes, Jorge Manuel de Oliveira. (2023) DNA hydroxymethylation differences underlie phenotypic divergence of somatic growth in Nile tilapia reared in common garden. Epigenetics
Academic article
Lee, N.S.; Kim, J.S.; Cho, W.J.; Lee, M.R.; Steiner, R.; Gompers, A.; Ling, D.; Zhang, J.; Sætrom, Pål; Behlke, Mark A.. (2008) miR-302b maintains "stemness" of human embryonal carcinoma cells by post-transcriptional regulation of Cyclin D2 expression. Biochemical and Biophysical Research Communications - BBRC
Academic article
Saito, Takaya; Sætrom, Pål. (2012) Target gene expression levels and competition between transfected and endogenous microRNAs are strong confounding factors in microRNA high-throughput experiments. Silence
Academic article
Røe, Oluf Dimitri; Fotopoulos, I; Nguyen, Olav Toai Duc; Nøst, Therese Haugdahl; Markaki, M; Lagani, Vincenzo; Mjelle, Robin; Sandanger, Torkjel M; Sætrom, Pål; Tsamardinos, I. (2022) Common MicroRNAs in Pre-diagnostic Serum Associated with Lung Cancer in Two Cohorts up to Eight Years Before Diagnosis: A HUNT Study. Journal of Thoracic Oncology
Conference abstract
Håndstad, Tony; Rye, Morten Beck; Mocnik, Rok; Drabløs, Finn; Sætrom, Pål. (2012) Cell-type specificity of ChIP-predicted transcription factor binding sites. BMC Genomics
Academic article
Voutila, J; Sætrom, Pål; Mintz, Paul J; Sun, Guihua; Alluin, Jessica; Rossi, JJ; Habib, Nagy A.; Kasahara, N.. (2012) Gene expression profile changes after short-activating RNA-mediated induction of endogenous pluripotency factors in human mesenchymal stem cells. Molecular Therapy Nucleic Acids
Academic article
Kroustallaki, Pinelopi; Lirussi, Lisa; Carracedo Huroz, Sergio; You, Panpan; Esbensen, Qin Ying; Götz, Alexandra; Jobert, Laure; Alsøe, Lene; Sætrom, Pål; Gagos, Sarantis. (2019) SMUG1 Promotes Telomere Maintenance through Telomerase RNA Processing. Cell reports
Academic article
Helvik, Snorre Andreas; Snøve, Ola; Sætrom, Pål. (2007) Reliable prediction of Drosha processing sites improves microRNA gene prediction. Bioinformatics
Academic article
Mjelle, Robin; Aass, Kristin Roseth; Sjursen, Wenche; Hofsli, Eva; Sætrom, Pål. (2020) sMETASeq: combined profiling of microbiota and host small RNAs. iScience
Academic article
Krokan, Hans Einar; Sætrom, Pål; Aas, Per Arne; Pettersen, Henrik P Sahlin; Kavli, Bodil Merete; Slupphaug, Geir. (2014) Error-free versus mutagenic processing of genomic uracil-Relevance to cancer. DNA Repair
Academic article
Snøve, Ola; Sætrom, Pål. (2006) Nobelpris for RNA-interferens. Tidsskrift for Den norske legeforening (Tidsskriftet)
Editorial
Bordin, Diana Lilian; Grooms, Kayla Mae; Montaldo, Nicola Pietro; Martin, Sarah Louise Fordyce; Sætrom, Pål; Samson, Leona D.; Bjørås, Magnar; van Loon, Barbara. (2024) Loss of alkyladenine DNA glycosylase alters gene expression in the developing mouse brain and leads to reduced anxiety and improved memory. DNA Repair
Academic article
Stracquadanio, Giovanni; Wang, Xuting; Wallace, Marsha D; Grawenda, Anna M.; Zhang, Ping; Hewitt, Juliet; Zeron-Medina, Jorge; Castro-Giner, Francesc; Tomlinson, Ian P; Goding, Colin R.. (2016) The importance of p53 pathway genetics in inherited and somatic cancer genomes. Nature Reviews Cancer
Academic article
Rye, Morten Beck; Sætrom, Pål; Håndstad, Tony; Drabløs, Finn. (2011) Clustered ChIP-Seq-defined transcription factor binding sites and histone modifications map distinct classes of regulatory elements. BMC Biology
Academic article
Matveeva, OV; Kang, YB; Spiridonov, AN; Sætrom, Pål; Nemtsov, VA; Ogurtsov, AY; Nechipurenko, YD; Shabalina, SA. (2010) Optimization of Duplex Stability and Terminal Asymmetry for shRNA Design. PLOS ONE
Academic article
Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Hegre, Siv Anita; Danielsen, Kjersti; Jenssen, Marita; Furberg, Anne-Sofie; Saunes, Marit; Hveem, Kristian; Sætrom, Pål. (2021) MicroRNA profiling of psoriatic skin identifies 11 miRNAs associated with disease severity. Experimental Dermatology
Academic article
Tiemann, Katrin; Höhn, Britta; Ehsani, Ali; Forman, Stephen J.; Rossi, John J.; Sætrom, Pål. (2010) Dual-targeting siRNAs. RNA: A publication of the RNA Society
Academic article
Fotopoulos, Ioannis; Nguyen, Olav Toai Duc; Nøst, Therese Haugdahl; Markaki, Maria; Lagani, Vincenzo; Mjelle, Robin; Sandanger, Torkjel Manning; Sætrom, Pål; Tsamardinos, Ioannis; Røe, Oluf Dimitri. (2024) Promising microRNAs in pre-diagnostic serum associated with lung cancer up to eight years before diagnosis: a HUNT study. Journal of Cancer Research and Clinical Oncology
Academic article
Huang, Kai-Wen; Reebye, Vikash; Czysz, Katherine; Ciriello, Simona; Dorman, Stephanie; Reccia, Isabella; Lai, Hong-Shiee; Peng, Ling; Kostomitsopoulos, Nikos; Nicholls, Joanna. (2020) Liver Activation of Hepatocellular Nuclear Factor-4α by Small Activating RNA Rescues Dyslipidemia and Improves Metabolic Profile. Molecular Therapy Nucleic Acids
Academic article
Potenza, Maria Letizia; Blankvoort, Stefan Matthias Adriaan; Carvalho, Miguel; Grimstvedt, Joachim Schweder; Di Maria, Valentina; Moan, Kristian Magnus; Raveendran Nair, Rajeevkumar; Flatset, Marcus Sandbukt; Zhang, Qiangwei; Thomas, Laurent Francois. (2024) Generation of an enhancer-driven gene expression viral tool specific to dentate granule cell-types through direct hippocampal injection. Frontiers in Neuroscience
Academic article
rie, D de; Abugesaissa, I; Alam, T; Arner, E; Ashoor, H; Åström, G; Babina, M; Bertin, N; Burroughs, AM; Carlisle, AJ. (2017) An integrated expression atlas of miRNAs and their promoters in human and mouse. Nature Biotechnology
Academic article
Pettersen, Caroline Hild Hakvåg; Samdal, Helle; Sætrom, Pål; Wibe, Arne; Hermansen, Erland; Schønberg, Svanhild Margrethe Arentz. (2023) The Salmon Oil OmeGo Reduces Viability of Colorectal Cancer Cells and Potentiates the Anti-Cancer Effect of 5-FU. Marine Drugs
Academic article
Robles, Ana I.; Olsen, Karina Standahl; Tsui, Dana W.T.; Georgoulias, Vassilis; Creaney, Jenette; Dobra, Katalin; Vyberg, Mogens; Minato, Nagahiro; Anders, Robert A.; Børresen-Dale, Anne-Lise. (2016) Excerpts from the 1st international NTNU symposium on current and future clinical biomarkers of cancer: innovation and implementation, June 16th and 17th 2016, Trondheim, Norway. Journal of Translational Medicine
Academic article
Hildrestrand, Gunn Annette; Rolseth, Veslemøy; Kunath, Nicolas; Suganthan, Rajikala; Jensen, Vidar; Bugaj, Anna Maria; Berrocal, Marion Silvana Fernandez; SIkko, Sunniva Bøe; Vetlesen, Susanne; Kusnierczyk, Anna. (2021) NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice. Communications Biology
Academic article
Sætrom, Pål. (2013) Designing dual-targeting siRNA duplexes having two active strands that combine siRNA and microRNA-like targeting. Methods in molecular biology
Academic article
Leung, A; Trac, C; Jin, W; Lanting, L; Akbany, A; Sætrom, Pål; Schones, DE; Natarajan, R. (2013) Novel Long Noncoding RNAs Are Regulated by Angiotensin II in Vascular Smooth Muscle Cells. Circulation Research
Academic article
Sætrom, Pål; Lehvaslaiho, Heikki; Stansberg, Christine; Awan, Haneef; Hesam, Ahmad. (2024) EOSC-ENTRUST D13.4 Year one version of EOSC-ENTRUST Blueprint & Interoperability Framework. zenodo
Professional article
Lien, Hilde Julie Tokle; Pedersen, Tina Therese; Jakobsen, Bente; Flatberg, Arnar; Chawla, Konika; Sætrom, Pål; Fenstad, Mona H.. (2023) Single-cell resolution of longitudinal blood transcriptome profiles in rheumatoid arthritis, systemic lupus erythematosus and healthy control pregnancies. Annals of the Rheumatic Diseases
Academic article
Stovner, Endre Bakken; Sætrom, Pål. (2019) PyRanges: efficient comparison of genomic intervals in Python. Bioinformatics
Academic article
Grapotte, Mathys; Saraswat, Manu; Bessière, Chloé; Menichelli, Christophe; Ramilowski, Jordan A.; Severin, Jessica; Hayashizaki, Yoshihide; Itoh, Masayoshi; Tagami, Michihira; Murata, Mitsuyoshi. (2022) Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network (Nature Communications, (2021), 12, 1, (3297), 10.1038/s41467-021-23143-7). Nature Communications
Corrigendum
Håndstad, Tony; Rye, Morten Beck; Drabløs, Finn; Sætrom, Pål. (2011) A ChIP-Seq Benchmark Shows That Sequence Conservation Mainly Improves Detection of Strong Transcription Factor Binding Sites. PLOS ONE
Academic article
Rye, Morten Beck; Sætrom, Pål; Drabløs, Finn. (2011) A manually curated ChIP-seq benchmark demonstrates room for improvement in current peak-finder programs. Nucleic Acids Research (NAR)
Academic article
Olsen, Lene Christin; Galler, Meital; Witter, Menno Peter; Sætrom, Pål; O'Reilly, Kally C. (2023) Transcriptional development of the hippocampus and the dorsal–intermediate–ventral axis in rats. Hippocampus
Academic article
Eije, KJ Von; Aagaard, Lars; Sætrom, Pål; Amarzguioui, M; Li, HT; Rossi, JJ. (2007) Prevention of HIV-1 viral escape upon RNAi treatment: Expression systems that generate multiple anti-HIV siRNAs. Human Gene Therapy
Conference abstract
Larose, Tricia L; Sætrom, Pål; Martinussen, Marit; Skogseth, Haakon; Sandanger, Torkjel M; Scélo, Ghislaine; McHale, Cliona M.; Jacobsen, Geir Wenberg; Smith, Martyn T.. (2019) In utero exposure to endocrine disrupting chemicals, micro-RNA profiles, and fetal growth: a pilot study protocol. Journal of Public Health Research
Academic article
Achar, Avinash; Sætrom, Pål. (2015) RNA motif discovery: a computational overview. Biology Direct
Academic literature review
Smith, DD; Sætrom, Pål; Snøve, Ola; Lundberg, C; Rivas, GE; Glackin, C; Larson, GP. (2008) Meta-analysis of breast cancer microarray studies in conjunction with conserved cis-elements suggest patterns for coordinate regulation. BMC Bioinformatics
Academic article
Lange, LA; Hu, Y; Zhang, H; Xue, C; Schmidt, EM; Tang, ZZ; Bizon, C; Lange, EM; Smith, JD; Turner, EH. (2014) Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol. American Journal of Human Genetics
Academic article
Chavali, Sreenivas; Bruhn, Sören; Tiemann, Katrin; Sætrom, Pål; Barrenäs, Fredrik; Saito, Takaya; Kanduri, Kartiek; Wang, Hui; Benson, Mikael. (2013) MicroRNAs act complementarily to regulate disease-related mRNA modules in human diseases. RNA: A publication of the RNA Society
Academic article
Pettersen, Henrik Sahlin; Galashevskaya, Anastasia; Doseth, Berit; Sousa, Mirta; Sarno, Antonio; Visnes, Torkild; Aas, Per Arne; Liabakk, Nina-Beate; Slupphaug, Geir; Sætrom, Pål. (2015) AID expression in B-cell lymphomas causes accumulation of genomic uracil and a distinct AID mutational signature. DNA Repair
Academic article
Sarker, Debashis; Plummer, Ruth; Meyer, Tim; Sodergren, Mikael H; Basu, Bristi; Chee, Cheng Ean; Huang, Kai-Wen; Palmer, Daniel H; Ma, Yuk Ting; Evans, T R Jeff. (2020) MTL-CEBPA, a Small Activating RNA Therapeutic Upregulating C/EBP-α, in Patients with Advanced Liver Cancer: A First-in-Human, Multicenter, Open-Label, Phase I Trial. Clinical Cancer Research
Academic article
Bugaj, Anna Maria; Kunath, Nicolas; Saasen, Vidar Langseth; Fernández Berrocal, Marion Silvana; Vankova, Ana; Sætrom, Pål; Bjørås, Magnar; Ye, Jing. (2024) Dissecting gene expression networks in the developing hippocampus through the lens of NEIL3 depletion. Progress in Neurobiology
Academic article
Konstantinidis, Ioannis; Anastasiadi, Dafni; Sætrom, Pål; Nedoluzhko, Artem; Mjelle, Robin; Podgorniak, Tomasz; Piferrer, Francesc; Fernandes, Jorge Manuel de Oliveira. (2021) Epigenetic mapping of the somatotropic axis in Nile tilapia reveals differential DNA hydroxymethylation marks associated with growth. Genomics
Academic article
Konstantinidis, Ioannis; Sætrom, Pål; Mjelle, Robin; Nedoluzhko, Artem; Robledo, Diego; Fernandes, Jorge Manuel de Oliveira. (2020) Major gene expression changes and epigenetic remodelling in Nile tilapia muscle after just one generation of domestication. Epigenetics
Academic article
Saito, Takaya; Sætrom, Pål. (2010) MicroRNAs – targeting and target prediction. New Biotechnology
Academic literature review
Mjelle, Robin; Sellæg, Kjersti; Sætrom, Pål; Thommesen, Liv; Sjursen, Wenche; Hofsli, Eva. (2017) Identification of metastasis-associated microRNAs in serum from rectal cancer patients. OncoTarget
Academic article
Urbarova, Ilona H.; Nøst, Therese Haugdahl; Skogholt, Anne Heidi; Mjelle, Robin; Paulsen, Erna-Elise; Dønnem, Tom; Andersen, Sigve; Markaki, Maria; Røe, Oluf Dimitri; Johansson, Mikael. (2022) Increased Levels of mRNAs and miRNAs Associated with Imminent and Advanced Lung Cancer. Journal of Thoracic Oncology
Conference abstract
Tingö, Lina; Ahlberg, Emelie; Johansson, Lovisa; Pedersen, Sindre Andre; Chawla, Konika; Sætrom, Pål; Cione, Erika; Simpson, Melanie Rae. (2021) Non-coding RNAs in human breast milk: A systematic review. Frontiers in Immunology
Academic literature review
Rolinski, Milosz; Montaldo, Nicola Pietro; Aksu, Merdane Ezgi; Martin, Sarah Fordyce; Brambilla, Alessandro; Kunath, Nicolas; Johansen, Jostein; Erlandsen, Sten Even; Liabakk, Nina-Beate; Rian, Kristin. (2021) Loss of Mediator complex subunit 13 (MED13) promotes resistance to alkylation through cyclin D1 upregulation. Nucleic Acids Research (NAR)
Academic article
Mjelle, Robin; Dima, Simona O; Bacalbasa, Nicolae; Chawla, Konika; Sorop, Andrei; Cucu, Dana; Herlea, Vlad; Sætrom, Pål; Popescu, Irinel. (2019) Comprehensive transcriptomic analyses of tissue, serum, and serum exosomes from hepatocellular carcinoma patients. BMC Cancer
Academic article
Olsen, Lene Christin; O'Reilly, Kally; Liabakk, Nina-Beate; Witter, Menno; Sætrom, Pål. (2017) MicroRNAs contribute to postnatal development of laminar differences and neuronal subtypes in the rat medial entorhinal cortex. Brain Structure and Function
Academic article
Røe, Oluf Dimitri; Mjelle, Robin; Sætrom, Pål; Andreassen, Trygve; Bathen, Tone Frost; Hveem, Kristian. (2016) Serum microRNAs/enriched pathways in lung cancer 1-4 years before diagnosis: A pilot study from the HUNT Biobank, Norway. Journal of Clinical Oncology
Conference abstract
Lundbæk, Marie Benner; Sætrom, Pål. (2011) Unconventional RNA interference – recent approaches to robust RNAi. European Pharmaceutical Review
Professional article
Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Danielsen, Kjersti; Jenssen, Marita; Furberg, Anne-Sofie; Saunes, Marit; Hveem, Kristian; Sætrom, Pål; Løset, Mari. (2019) Differentially Expressed miRNAs and mRNAs in Psoriatic Skin. Journal of Investigative Dermatology
Conference abstract
Sjögren, A.-K.M.; Barrenäs, Fredrik; Muraro, Antonella; Gustafsson, M; Sætrom, Pål; Wang, H; Benson, M.. (2012) Monozygotic twins discordant for intermittent allergic rhinitis differ in mRNA and protein levels. Allergy. European Journal of Allergy and Clinical Immunology
Academic article
Olsen, Maria Belland; Hildrestrand, Gunn Annette; Scheffler, Katja; Vinge, Leif Erik; Alfsnes, Katrine; Palibrk, Vuk; Wang, Junbai; Neurauter, Christine Gran; Gomez, Luisa Fernanda Luna; Johansen, Jostein. (2017) NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture. Cell reports
Academic article
Saito, Takaya; Sætrom, Pål. (2010) A two-step site and mRNA-level model for predicting microRNA targets. BMC Bioinformatics
Academic article
Reddy, MA; Chen, Z; Park, JT; Wang, M; Lanting, L; Zhang, Q; Bhatt, K; Leung, A; Wu, X; Putta, S. (2014) Regulation of inflammatory phenotype in macrophages by a diabetes-induced long noncoding RNA. Diabetes
Academic article
Razick, Sabry; Mocnik, Rok; Thomas, Laurent; Ryeng, Einar; Drabløs, Finn; Sætrom, Pål. (2014) The eGenVar data management system--cataloguing and sharing sensitive data and metadata for the life sciences. Database: The Journal of Biological Databases and Curation
Academic article
Neurauter, Christine Gran; Pannone, Marco; Sousa, Mirta; Wang, Wei; Kusnierczyk, Anna; Luna, Luisa; Sætrom, Pål; Scheffler, Katja; Bjørås, Magnar. (2024) Enhanced glutathione levels confer resistance to apoptotic and ferroptotic programmed cell death in NEIL DNA glycosylase deficient HAP1 cells. Free Radical Biology & Medicine
Academic article
Birkeland, Olaf René; Snøve, Ola; Halaas, Arne; Nedland, Magnar; Sætrom, Pål. (2006) The petacomp Machine - A MIMD Cluster for parallel pattern-mining. Proceedings IEEE International Conference on Cluster Computing
Academic article
Sætrom, Pål; Biesinger, Jacob; Li, Sierra M.; Smith, David; Thomas, Laurent Francois; Majzoub, Karim; Rivas, Guillermo E.; Alluin, Jessica; Rossi, John J.; Krontiris, Theodore G.. (2009) A Risk Variant in an miR-125b Binding Site in BMPR1B Is Associated with Breast Cancer Pathogenesis. Cancer Research
Academic article
Ehsani, A; Sætrom, Pål; Zhang, J; Alluin, J; Li, HT; Snøve, Ola; Aagaard, L; Rossi, JJ. (2010) Rational Design of Micro-RNA-like Bifunctional siRNAs Targeting HIV and the HIV Coreceptor CCR5. Molecular Therapy
Academic article
Langkilde, Ane; Olsen, Lene Christin; Sætrom, Pål; Drabløs, Finn Sverre; Besenbacher, Søren; Raaby, Line; Johansen, Claus; Iversen, Lars. (2016) Pathway Analysis of Skin from Psoriasis Patients after Adalimumab Treatment Reveals New Early Events in the Anti-Inflammatory Mechanism of Anti-TNF-α. PLOS ONE
Academic article
Helvik, Snorre Andreas; Snøve, Ola; Sætrom, Pål. (2006) Reliable prediction of Drosha processing sites improves microRNA gene prediction. Bioinformatics
Academic article
Landfors, Miriam; Johansen, Jostein; Aronsen, Jan Magnus; Vågbø, Cathrine Broberg; Doré, Louis C.; He, Chuan; Sjaastad, Ivar; Sætrom, Pål; Fedorcsák, Péter; Dahl, John Arne. (2017) Genome-wide profiling of DNA 5-hydroxymethylcytosine during rat Sertoli cell maturation. Cell Discovery
Academic article
Thomas, Laurent; Sætrom, Pål. (2012) Single Nucleotide Polymorphisms Can Create Alternative Polyadenylation Signals and Affect Gene Expression through Loss of MicroRNA-Regulation. PLoS Computational Biology
Academic article
Kim, Daniel H.; S�trom, P�l; Sn�ve, Ola; Rossi, John J.. (2008) MicroRNA-directed transcriptional gene silencing in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Academic article
Lefol, Yohan Pierre; Hasle, Geir Amund; Hegre, Siv Anita; Samdal, Helle; Sætrom, Pål. (2025) Using pseudotime derivative on single-cell RNA sequencing data to identify genes undergoing cell cycle regulation. Bioinformatics Advances
Academic article
Lefol, Yohan Pierre; Korfage, Tom; Mjelle, Robin; Prebensen, Christian Haugland; Lüders, Torben; Müller, Bruno; Krokan, Hans Einar; Sarno, Antonio; Alsøe, Lene; Berdal, Jan-Erik. (2023) TiSA: TimeSeriesAnalysis - A pipeline for the analysis of longitudinal transcriptomics data. NAR Genomics and Bioinformatics
Academic article
Nøst, Therese Haugdahl; Skogholt, Anne Heidi; Urbarova, Ilona Halva; Mjelle, Robin; Paulsen, Erna-Elise; Dønnem, Tom; Andersen, Sigve; Markaki, Maria; Røe, Oluf Dimitri; Johansson, Mikael. (2022) Increased levels of microRNA-320 in blood serum and plasma is associated with imminent and advanced lung cancer. Molecular Oncology
Academic article
Aagaard, Lars; Zhang, J; Eije, K J von; Li, H; Saetrom, P; S�trom, P�l; Amarzguioui, M; Rossi, John J.. (2008) Engineering and optimization of the miR-106b cluster for ectopic expression of multiplexed anti-HIV RNAs. Gene Therapy
Academic article
Soifer, Harris S.; Sano, Masayuki; Sakurai, Kumi; Chomchan, Pritsana; S�trom, P�l; Sherman, Mark A.; Collingwood, Michael A.; Behlke, Mark A.; Rossi, John J.. (2008) A role for the Dicer helicase domain in the processing of thermodynamically unstable hairpin RNAs. Nucleic Acids Research (NAR)
Academic article
Hegre, Siv Anita; Samdal, Helle; Klima, Antonin; Stovner, Endre Bakken; Nørsett, Kristin Gabestad; Liabakk, Nina-Beate; Olsen, Lene Christin; Chawla, Konika; Aas, Per Arne; Sætrom, Pål. (2021) Joint changes in RNA, RNA polymerase II, and promoter activity through the cell cycle identify non-coding RNAs involved in proliferation. Scientific Reports
Academic article
Voutila, Jon; Reebye, Vikash; Roberts, Thomas C.; Protopapa, Pantelitsa; Andrikakou, Pinelopi; Blakey, David C.; Habib, Robert; Huber, Hans; Sætrom, Pål; Rossi, John J.. (2017) Development and mechanism of small activating RNA targeting CEBPA, a novel therapeutic in clinical trials for liver cancer. Molecular Therapy
Academic article
Sætrom, Pål; Snøve, Ola. (2007) Robust machine learning algorithms predict microRNA genes and targets. Methods in Enzymology
Academic article
Yoon, Sorah; Huang, Kai-Wen; Reebye, Vikash; Mintz, Paul; Tien, Yu-Wen; Lai, Hong-Shiee; Sætrom, Pål; Reccia, Isabella; Swiderski, Piotr; Armstrong, Brian. (2016) Targeted Delivery of C/EBPα -saRNA by Pancreatic Ductal Adenocarcinoma-specific RNA Aptamers Inhibits Tumor Growth in Vivo. Molecular Therapy
Academic article
Simpson, Melanie Rae; Brede, Gaute; Johansen, Jostein; Johnsen, Roar; Storrø, Ola; Sætrom, Pål; Øien, Torbjørn. (2015) Human breast milk miRNA, maternal probiotic supplementation and atopic dermatitis in offspring. PLOS ONE
Academic article
Thomas, Laurent; Sætrom, Pål. (2014) Circular RNAs are depleted of polymorphisms at microRNA binding sites. Bioinformatics
Academic article
Montaldo, Nicola Pietro; Bordin, Diana Lilian; Brambilla, Alessandro; Rösinger, Marcel; Martin, Sarah Fordyce; Bjørås, Karine Øian; Bradamante, Stefano; Aas, Per Arne; Furrer, Antonia; Olsen, Lene Christin. (2019) Alkyladenine DNA glycosylase associates with transcription elongation to coordinate DNA repair with gene expression. Nature Communications
Academic article
Reebye, Vikash; Sætrom, Pål; Mintz, Paul J; Rossi, JJ; Kasahara, Noriyuki; Nteliopoulos, G; Nicholls, Joanna P; Haoudi, Abdelali; Gordon, Myrtle YA; Habib, Nagy A. (2013) A short-activating RNA oligonucleotide targeting the islet β-cell transcriptional factor MafA in CD34(+) cells. Molecular Therapy Nucleic Acids
Academic article
Hofsli, Eva; Sætrom, Pål; Ness-Jensen, Eivind; Surcel, Helja-Marja; Mjelle, Robin. (2025) Can circulating microRNAs predict colorectal cancer? Results from a nested case–control study of pre-diagnostic serum samples from two prospective biobanks. BMC Cancer
Academic article

Part of book/report

Snøve, Ola; Sætrom, Pål. (2009) Animal MicroRNA gene prediction.
Academic chapter
Sætrom, Pål; Snøve, Ola. (2007) Machine learning predicts microRNA target sites.
Academic chapter
Sarno, Antonio; Sætrom, Pål; Kavli, Bodil Merete; Pettersen, Henrik Sahlin. (2018) Genomic Uracil and Cancer.
Non-fiction chapter
Lundbæk, Marie B; Sætrom, Pål. (2013) RNAi Screening and Assays.
Academic chapter
Sætrom, Pål; Birkeland, Olaf René; Snøve, Ola. (2007) Boosting Improves Stability and Accuracy of Genetic Programming in Biological Sequence Classification.
Academic chapter

Student thesis or dissertation

Lien, Hilde Julie Tokle; Sætrom, Pål; Fenstad, Mona Høysæter. (2025) Identifying cell type and gene expression changes in pregnant women with rheumatoid arthritis and systemic lupus erythematosus. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Sætrom, Pål. (2005) Hardware accelerated genetic programming for pattern mining in strings. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Sætrom, Pål. (2005) Hardware accelerated genetic programming for pattern mining in strings. NTNU-Trykk
Doctoral thesis

Teaching

Courses

Outreach

2025

Conference poster

Lien, Hilde Julie Tokle; Pedersen, Tina Therese; Jakobsen, Bente; Flatberg, Arnar; Leirvik, Gunnhild Vatne; Haug, Markus; Fenstad, Mona H.; Sætrom, Pål. (2025) Single-cell RNA sequencing of pregnant women with SPRA and SLE: Uncovering cell-independent IFN signatures in SLE and a key role of MAIT and CD4 T-cells in SPRA. 13th International Conference on Reproduction, Pregnancy and Rheumatic diseases
Lecture

Silva Lopes Oliveira, Rafael; Sætrom, Pål; Grønberg, Bjørn Henning; Halvorsen, Tarje Onsøien. (2025) Treatment outcomes of chemoradiotherapy in LS SCLC according to molecular subtypes. Treatment outcomes of chemoradiotherapy in LS SCLC according to molecular subtypes
Conference lecture

Silva Lopes Oliveira, Rafael; Sætrom, Pål; Halvorsen, Tarje Onsøien; Grønberg, Bjørn Henning. (2025) Subtyping, radiosensitivity and treatment outcomes in LS SCLC. Subtyping, radiosensitivity and treatment outcomes in LS SCLC
Conference poster

Killingberg, Kristin Toftaker; Sætrom, Pål; Grønberg, Bjørn Henning; Halvorsen, Tarje Onsøien; Figueiredo, Filipe Carlos Pereira dos Reis. (2025) Serum microRNAs are associated with treatment response and disease progression in limited stage small cell lung cancer. IASLC Hot topic in basic and translational science small cell lung cancer

2024

Conference lecture

Nguyen, Olav Toai Duc; Fotopoulos, Y; Nøst, Therese Haugdahl; Markaki, Maria; Lagani, Vincenzo; Sætrom, Pål; Tsamadinos, Ioannis; Røe, Oluf Dimitri. (2024) Differentially expressed microRNAs in prediagnostic serum linked to lung cancer up to eight years before diagnosis in prospective, population-based cohorts: A HUNT study. Clinical Science Symposium, 2024 ASCO Annual Meeting
Conference poster

Andersson-Rusch, Clara; Quist-Løkken, Ingrid; Sætrom, Pål; Hanif, Md Abu; Rolinski, Milosz; Møen, Johanna; Roman, Naiara Campos; Misund, Kristine; Beisvag, Vidar; Aas, Per Arne. (2024) Whole genome CRISPR knockout screen reveals key function for ID3 in regulating myeloma cell survival via TCF3 and c-MYC. TGF-β Superfamily

2023

Conference poster

Andersson-Rusch, Clara Leticia; Quist-Løkken, Ingrid; Sætrom, Pål; Beisvag, Vidar; Rolinski, Milosz; Møen, Johanna; Misund, Kristine; Aas, Per Arne; van Loon, Barbara; Holien, Toril. (2023) Genome-Wide CRISPR/Cas9 Knock-out Screen Identifies Apoptosis-Relevant Genes in Multiple Myeloma. 65th ASH Annual Meeting and Exposition
Conference poster

Zaytseva-Zotova, Daria; Haslene-Hox, Hanne; Arlov, Øystein; Hoel, Andrea Draget; Mjelle, Robin; Strand, Wenche; Solbu, Anita Akbarzadeh; Klinkenberg, Geir; Halaas, Øyvind; Beisvåg, Vidar. (2023) Alginate hydrogel characteristics regulate NHDF biology. European Society for Biomaterials
Conference poster

Strand, Berit Løkensgard; Haslene-Hox, Hanne; Sætrom, Pål; Zaytseva-Zotova, Daria; Mjelle, Robin; Arlov, Øystein; Strand, Wenche; Solbu, Anita Akbarzadeh; Klinkenberg, Geir; Halaas, Øyvind. (2023) Alginate hydrogel characteristics regulate NHDF biology. ScSB 2023
Conference poster

Lund-Hanssen, Charlotte; Olsen, Lene Christin; Thomas, Laurent Francois; O'Reilly, Kally; Witter, Menno Peter; Sætrom, Pål. (2023) The Conserved Expression of Long Non-Coding RNAs in the Entorhinal Cortex During Postnatal Development. Gene Regulatory Mechanisms in Neural Fate Decisions
Conference lecture

Haslene-Hox, Hanne; Chahal, Aman Singh; Arlov, Øystein; Øynebråten, Ingrid Ryge; Zaytseva-Zotova, Daria; Vikenes, Anette; Hoel, Andrea Draget; Mjelle, Robin; Strand, Wenche Iren; Solbu, Anita Akbarzadeh. (2023) Alginate hydrogel characteristics regulate fibroblast biology. Norsk Biokjemisk selskaps kontaktmøte 2023
Conference poster

Bösl, Korbinian; Bianchini, Federico; Fatima, Nazeefa; Keyvani, Pedram A; Kalhovd, Siri; Tekle, Kidane M; Hjerde, Erik; Sætrom, Pål; Sandve, Simen Rød; Petersen, Kjell. (2023) End-to-end data management tool assembly for Norwegian life scientist. ELIXIR All Hands 2023

2022

Lecture

Chahal, Aman S; Strand, Berit Løkensgard; Haslene-Hox, Hanne; Sætrom, Pål. (2022) An out of body experience: Cell culture in 3D. Forskning for folket
Conference poster

Lund-Hanssen, Charlotte; Olsen, Lene Christin; Thomas, Laurent Francois; Sætrom, Pål. (2022) The Conserved Expression of Long Non-Coding RNAs in the Entorhinal Cortex During Postnatal Development. 8th Annual NORBIS Conference
Conference poster

Nøst, Therese Haugdahl; Urbarova, Ilona Halva; Skogholt, Anne Heidi; Mjelle, Robin; Paulsen, Erna Elise; Dønnem, Tom; Andersen, Sigve; Markaki, Maria; Røe, Oluf Dimitri; Johansson, Mikael. (2022) Increased levels of mRNAs and miRNAs associated with imminent and advanced lung cancer. IASLC 2022 World Conference on Lung Cancer

2021

Conference lecture

Konstantinidis, Ioannis; Sætrom, Pål; Brieuc, Marine Servane Ono; Jakobsen, Kjetill Sigurd; Liedtke, Hannes; Pohlmann, Caroline; Tsoulia, Thomais; Fernandes, Jorge Manuel de Oliveira. (2021) DNA hydroxymethylation is linked to higher growth rate in Nile tilapia. X FIRMA 2021
Conference lecture

Nøst, Therese Haugdahl; Skogholt, Anne Heidi; Mjelle, Robin; Grønberg, Bjørn Henning; Sandanger, Torkjel M; Sætrom, Pål. (2021) microRNA levels in serum at diagnosis are predictive for lung cancer. Forskningskonferansen for Kreftforeningens nasjonale ekspertgruppe for lungekreftforskning
Conference lecture

Konstantinidis, Ioannis; Sætrom, Pål; Liedtke, Hannes; Pohlmann, Caroline; Tsoulia, Thomais; Fernandes, Jorge Manuel de Oliveira. (2021) Differences in liver DNA hydroxymethylation reflect the growth phenotype. 6th Genomics in Aquaculture Symposium

2019

Conference poster

Skogholt, Anne Heidi; Jensen, Espen Drevland; Ryeng, Einar; Grønberg, Bjørn Henning; Skorpen, Frank; Schønberg, Svanhild Margrethe Arentz; Sætrom, Pål. (2019) Robust messenger RNA (mRNA) markers in blood for lung cancer diagnosis. ASHG
Conference lecture

Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Danielsen, Kjersti; Jenssen, Marita; Furberg, Anne-Sofie; Saunes, Marit; Hveem, Kristian; Sætrom, Pål; Løset, Mari. (2019) Combined mRNA and miRNA Analysis of Psoriatic Skin. The 34th Nordic Congress of Dermatology & Venereology
Conference poster

Løset, Mari; Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Danielsen, Kjersti; Jenssen, Marita; Furberg, Anne-Sofie; Saunes, Marit; Hveem, Kristian; Sætrom, Pål. (2019) Differentially Expressed miRNAs and mRNAs in Psoriatic Skin. American Society for Human Genetics Annual Meeting
Conference poster

Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Danielsen, Kjersti; Jenssen, Marita; Furberg, Anne-Sofie; Saunes, Marit; Hveem, Kristian; Sætrom, Pål; Løset, Mari. (2019) Differentially Expressed miRNAs and mRNAs in Psoriatic Skin. European Society for Dermatological Research Annual Meeting
Conference poster

Samdal, Helle; Hegre, Siv Anita; Klima, Antonin; Stovner, Endre Bakken; Nørsett, Kristin Gabestad; Liabakk, Nina-Beate; Aas, Per Arne; Sætrom, Pål. (2019) Functional evaluation of long non-coding RNAs with potential roles during cell replication. Long Noncoding RNAs: From Molecular Mechanism to Functional Genetics
Lecture

Zaytseva-Zotova, Daria; Ruohola, Rita; Strand, Wenche Iren; Akbarzadeh, Anita; Haslene-Hox, Hanne; Arlov, Øystein; Vikenes, Anette; Hoel, Andrea Draget; Halaas, Øyvind; Sætrom, Pål. (2019) Alginate hydrogels with tailored mechanical and biological properties for 3D fibroblast culture. DigitalLife 2019
Conference lecture

Konstantinidis, Ioannis; Sætrom, Pål; Fernandes, Jorge Manuel de Oliveira. (2019) Tissue-specific hydroxymethylome profiles of Nile tilapia Oreochromis niloticus at single nucleotide resolution. Aquaculture 2019

2018

Conference poster

Halaas, Øyvind; Sætrom, Pål; Arlov, Øystein; Haslene-Hox, Hanne; Beisvag, Vidar; Aachmann, Finn Lillelund; Åm, Heidrun; Klinkenberg, Geir; Sletta, Håvard; Strand, Berit Løkensgard. (2018) 3DLife – Emulating life in 3D with digital and experimental tissue models. DigitalLife 2018
Conference poster

Olsen, Lene Christin; Sætrom, Pål; Witter, Menno. (2018) Detecting early molecular events in a mouse model of Alzheimer’s disease (AD) using single cell RNA sequencing. NORBIS annual conference
Conference poster

Blankvoort, Stefan; Thomas, Laurent; Witter, Menno; Sætrom, Pål; cotney, Justin; Kentros, Clifford. (2018) The marked diversity of unique cortical enhancers enables neuron-specific tools by Enhancer-Driven Gene Expression (EDGE). FENS 2018
Conference lecture

Konstantinidis, Ioannis; Sætrom, Pål; Fernandes, Jorge Manuel de Oliveira. (2018) Fast muscle hydroxymethylation patterns in wild and captive Nile tilapia (Oreochromis niloticus) provide insights into fish domestication. GIA2018: 5th International Symposium on Genomics in Aquaculture
Conference poster

Hegre, Siv Anita; Klima, Antonin; Stovner, Endre Bakken; Samdal, Helle; Nørsett, Kristin Gabestad; Liabakk, Nina-Beate; Aas, Per Arne; Sætrom, Pål. (2018) Long non-coding RNAs in epigenetic inheritance. Noncoding RNAs: Form, Function, Physiology

2017

Conference poster

Hegre, Siv Anita; Stovner, Endre Bakken; Sætrom, Pål. (2017) Find diffusely enriched chromatin domains in ChIP-seq data with epic. Keystone Symposia "Noncoding RNAs: From disease to targeted therapeutics"
Conference poster

Hegre, Siv Anita; Klima, Antonin; Aas, Per Arne; Liabakk, Nina-Beate; Sætrom, Pål. (2017) Meta-Analysis of RNA expression identifies human cell-cycle genes. Keystone Symposia "Noncoding RNAs: From Disease to Targeted Therapeutics"
Lecture

Konstantinidis, Ioannis; Fernandes, Jorge Manuel de Oliveria; Sætrom, Pål. (2017) The first hydroxymethylation map of fast muscle in Nile tilapia (Oreochromis niloticus). Aquaculture Europe 2017
Conference poster

Klima, Antonin; Hegre, Siv Anita; Aas, Per Arne; Liabakk, Nina-Beate; Sætrom, Pål. (2017) Meta-analysis of RNA expression identifies human cell-cycle genes. Norbis – Annual National Conference
Conference poster

Hegre, Siv Anita; Samdal, Helle; Klima, Antonin; Stovner, Endre Bakken; Nørsett, Kristin; Aas, Per Arne; Liabakk, Nina-Beate; Sætrom, Pål. (2017) Long non-coding RNAs in epigenetic inheritance * Won Poster prize of 250 EUR at the EMBO|EMBL Symposium. EMBO EMBL Symposium "The Non-Coding genome"

2016

Conference lecture

Krokan, Hans Einar; Kavli, Bodil Merete; Pettersen, Henrik Sahlin; Sætrom, Pål; Galashevskaya, Anastasia; Sarno, Antonio; Aas, Per Arne; Doseth, Berit; Slupphaug, Geir. (2016) Genomic Uracil - Important carcinogenic mutagen but normal intermediate in adaptive immunity. The 10th International 3R (Replication, recombination and repair) Symposium, Matsue, Japan
Conference lecture

Klima, Antonin; Sætrom, Pål. (2016) Transcriptome-Wide Discovery of Cell-Cycle Genes. Norbis – Annual National Conference
Conference lecture

Krokan, Hans Einar; Pettersen, Henrik Sahlin; Mjelle, Robin; Hegre, Siv Anita; Sætrom, Pål; Drabløs, Finn Sverre; Sarno, Antonio; Galashevskaya, Anastasia; Aas, Per Arne; Liabakk, Nina-Beate. (2016) REGULATION OF BASE EXCISION REPAIR – CANONICAL AND NON-CANONICAL PROCESSING OF GENOMIC URACIL. 10th International Multiconference on Bioinformatics of Genome Regulation and Structure\Systems Biology
Conference poster

Johansen, Jostein; Chawla, Konika; Olsen, Lene Christin; Sætrom, Pål. (2016) Bioinformatics Core Facility. Seminar for staff at the future Faculty of Medicine and Health Sciences
Lecture

Krokan, Hans Einar; Slupphaug, Geir; Sætrom, Pål; Sarno, Antonio; Galashevskaya, Anastasia; Lundbæk, Marie Benner; Aas, Per Arne; Krokan, Ruth Haaland; Liabakk, Nina-Beate; Pettersen, Henrik Sahlin. (2016) Genomic uracil - Important carcinogenic mutagen but normal intermediate in adaptive immunity. Eurotox 2016

2015

Conference poster

Simpson, Melanie Rae; Brede, Gaute; Johansen, Jostein; Storrø, Ola; Johnsen, Roar; Sætrom, Pål; Øien, Torbjørn. (2015) Human breast milk miRNA, maternal probiotics supplementation and atopic dermatitis in offspring (poster). 12th International Symposium on Milk Genomics and Human Health
Conference lecture

Simpson, Melanie Rae; Brede, Gaute; Johansen, Jostein; Storrø, Ola; Johnsen, Roar; Sætrom, Pål; Øien, Torbjørn. (2015) Human breast milk miRNA, maternal probiotic supplementation and atopic dermatitis (oral presentation). 12th International Symposium on Milk Genomics and Human Health

2014

Conference lecture

Sætrom, Pål. (2014) The effect of the core RISC-component Ago2 on microRNA composition and regulation. Illumina Sequencing Seminar
Interview

Johnsen, Ingvild Bjellmo; Løvstakken, Lasse; Åsvold, Bjørn Olav; Høydal, Morten; Sætrom, Pål; Bonnevie, Tora. (2014) NTNUs stjerneforskere.
Conference lecture

Hansen, Maren Fridtjofsen; Johansen, Jostein; Bjørnevoll, Inga; Sylvander, Anna Elisabeth; Steinsbekk, Kristin Solum; Sætrom, Pål; Sandvik, Arne Kristian; Drabløs, Finn; Sjursen, Wenche. (2014) Using exome sequencing for identification of high-risk genetic variants in a family predisposed for colorectal cancer. COST Action BM1206 Meeting
Conference lecture

Sætrom, Pål. (2014) Management and Analyses of Population Data on Genetic Variation. 2nd Annual Next Generation Sequencing Data Congress
Interview

Sætrom, Pål. (2014) Når feil kopi kan gjøre deg syk.
Lecture

Razick, Sabry; Sætrom, Pål. (2014) Data advertising and managing platform for biobanks - a use case for the eGenVar data management system. European, Middle Eastern and Afran Society for Biopreservation & Biobanking

2013

Conference poster

Pena-Diaz, Javier; Hegre, Siv Anita; Anderssen, Endre; Aas, Per Arne; Mjelle, Robin; Gilfillan, Gregor Duncan; Lyle, Robert; Drabløs, Finn; Krokan, Hans Einar; Sætrom, Pål. (2013) Transcription profiling during the cell cycle shows that a subset of Polycomb-targeted genes is upregulated during DNA replication. Norwegian Biochemical Society Contact Meeting
Conference lecture

Sætrom, Pål; Thomas, Laurent. (2013) Finding SNPs that affect microRNA regulation. 10th International RNAi, MicroRNAs & Single Cell Biology – 2013 Meeting
Interview

Sætrom, Pål. (2013) Innebygd klokke måler alder til menneskeleg vev.
Conference lecture

Sætrom, Pål. (2013) Transcription profiling during the cell cycle shows that a subset of Polycomb-targeted genes is up-regulated during DNA replication. Department seminar

2012

Conference lecture

Drabløs, Finn; Rye, Morten Beck; Klepper, Kjetil; Sætrom, Pål. (2012) Definition and analysis of gene sets from time series data. FANTOM time-courses meeting
Conference lecture

Sætrom, Pål. (2012) Epigenetics and the human cell-division cycle. Department seminar
Lecture

Sætrom, Pål. (2012) Født sånn eller blitt sånn? Hvordan samvirker gener og miljø. Lions medlemsmøte
Interview

Torheim, Norunn K.; Sætrom, Pål. (2012) Nye verktøy i jakten på sykdomsårsaker.

2011

Conference poster

Rye, Morten Beck; Drabløs, Finn; Sætrom, Pål; Håndstad, Tony. (2011) Epigenetic Influence on Cell-type specific peaks from ChIP-Seq data. Histone code: Fact or fiction?
Conference poster

Rye, Morten Beck; Sætrom, Pål; Håndstad, Tony; Drabløs, Finn. (2011) Clusters of ChIP-Seq defined transcription factor binding sites map regulatory elelemnts in the human genome. Unanswered Questions in Transcription, Annual international Symposium
Conference lecture

Sætrom, Pål. (2011) Handling, integrating, and analysing biobank data in a hypothesis-driven framework. Bioinformatics Seminars
Conference lecture

Sætrom, Pål. (2011) Analyzing and designing small RNA-mediated gene regulation. Bioinformatics for Regulatory Genomics (BioRegSIG) - Special Interest Group (SIG) at Intelligent Systems for Molecular Biology
Conference lecture

Sætrom, Pål. (2011) Tools for analyzing and designing small RNA-mediated gene regulation. Invited seminar

2010

Conference poster

Saito, Takaya; Sætrom, Pål. (2010) Poster presentation: A two-step site and mRNA-level model for predicting microRNA target. RECOMB Computational Cancer Biology
Conference lecture

Sætrom, Pål. (2010) Tools for analyzing and designing small RNA-mediated gene regulation. City of Hope’s Beckman Research Institute seminar series
Conference poster

Thomas, Laurent Francois; Saito, Takaya; Sætrom, Pål. (2010) Identifying causative variants in microRNA target sites. RECOMB Computational Cancer Biology
Conference lecture

Sætrom, Pål. (2010) Bioinformatics of small RNA-mediated gene regulation. Seminar at Science for Life Laboratory (SciLifeLab)
Conference lecture

Sætrom, Pål. (2010) Bioinformatics of small RNA-mediated gene regulation. Systems Biology meetings at NTNU
Conference lecture

Sætrom, Pål. (2010) Epigenetic and microRNA regulation of the cell cycle. Onsdagsmøte IKM

2009

Conference poster

Hegre, Siv Anita; Sætrom, Pål; Aas, Per Arne; Olsen, Lene Christin; Lundbæk, Marie Benner; Diaz, Javier Pena; Krokan, Hans Einar. (2009) Multiple microRNAs appear to regulate the DNA repair enzyme UNG2 during the cell cycle. MicroRNA and Cancer Conference
Conference lecture

Sætrom, Pål. (2009) Synergistic regulation by microRNAs. Third Bertinoro Systems Biology Workshop

2008

Conference lecture

Sætrom, Pål. (2008) Cooperative microRNA Targeting and Regulation. Bioinformatics-meeting 2008
Conference lecture

Sætrom, Pål. (2008) Cooperative microRNA Targeting and Regulation. Current Topics in RNA Biology
Lecture

Sætrom, Pål. (2008) Små RNA - viktige i sykdom og lovende terapeutiske kandidater. Sluttrapporteringsseminar for FUGE
Conference lecture

Sætrom, Pål. (2008) Synergistic microRNA-like targeting by short interfering RNAs can give robust HIV-inhibition. Bioinformatics Wednesday seminars
Conference lecture

Sætrom, Pål. (2008) Gene regulation by microRNAs and microRNA regulation of DNA repair. Genes, Genomes and Evolution: Structure and Hyperstructure
Conference lecture

Sætrom, Pål. (2008) Cooperative microRNA Targeting and Regulation. Norwegian Bioinformatics Forum 2008
Conference lecture

S�trom, P�l. (2008) Cooperative microRNA Targeting and Regulation – Applications in siRNA Design. NMC Møte
Conference lecture

Sætrom, Pål. (2008) Cooperative microRNA Targeting and Regulation. RNAi Europe

2007

Conference lecture

Sætrom, Pål. (2007) Cooperative microRNA targeting and robust inhibition of HIV. 2nd RNA Interference Conference
Conference lecture

Sætrom, Pål; Heale, Bret S.; Snøve, Ola; Aagaard, Lars; Alluin, Jessica; Rossi, John J.. (2007) Distance Constraints Between MicroRNA Target Sites Dictate Efficacy and Cooperativity. RNA 2007 - Twelfth Annual Meeting of the RNA Society
Conference lecture

Sætrom, Pål. (2007) The roles of microRNAs and transcription factors in gene regulation and tissue specific expression. FUGE seminar
Conference lecture

Sætrom, Pål. (2007) Distance Constraints Between MicroRNA Target Sites Dictate Efficacy and Cooperativity. MicroRNAs Europe 2007 Meeting on MicroRNAs: Biology to Development and Disease
Conference lecture

Sætrom, Pål. (2007) The roles of microRNAs and transcription factors in gene regulation and tissue specific expression. BBB Seminars - The BioMedical and BioSciences Lecture Series

2006

Conference lecture

Sætrom, Pål. (2006) Predicting microRNA targets - challenges and solutions. Bioinformatics 2006
Conference lecture

Sætrom, Pål; Birkeland, Olaf René; Snøve, Ola. (2006) Boosting improves stability and accuracy of genetic programming in biological sequence classification. Genetic Programming Theory and Practice IV

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Pål Sætrom

Pål Sætrom

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