Siril Skaret Bakke
About
I am a innovation manager and I want to help opportunities discovered through research at NTNU and HMN (Central Norway Regional Health Authority) become reality in the marked.
I am a civil engineer in biotechnology and a PhD in pharmacology. Previously, I have worked in several laboratories both nationally and internationally within different disciplines. Through my PhD I became a specialist in lipid metabolism associated with type 2 diabetes and obesity in muscle cells. I also have experience with different live cell imaging techniques and teaching, as well as analysis with big gene expression data sets.
I have worked at Centre of Molecular Inflammation Research (CEMIR) at NTNU. As a post doc I was working on revealing the mechanisms behind inflammation and complement system activation in regards to cholesterol crystal accumulation in atherosclerotic plaques and to find new novel treatments against atherosclerosis. Thereafter I worked as a researcher studying TLR4 mediated signalling in relation to human diseases.15 september 2014 - 1st of june I was in the lab of Prof Eicke Latz, Institute of Innate Immunity, University of Bonn, Germany.
In addition, I have worked as a consultant for the clinical research unit Central Norway (Klinforsk) in data management for clinical studies and am a super user for eFORSK.
Publications
2023
-
Nilsen, Kaja Elisabeth;
Zhang, Boyao;
Skjesol, Astrid;
Ryan, Liv;
Vagle, Hilde;
Bøe, Maren Helene.
(2023)
Peptide derived from SLAMF1 prevents TLR4-mediated inflammation in vitro and in vivo.
Life Science Alliance (LSA)
Academic article
2022
-
Mundal, Siv Boon;
Rakner, Johanne Johnsen;
Silva, Gabriela;
Gierman, Lobke;
Austdal, Marie;
Basnet, Purusotam.
(2022)
Divergent Regulation of Decidual Oxidative-Stress Response by NRF2 and KEAP1 in Preeclampsia with and without Fetal Growth Restriction.
International Journal of Molecular Sciences
Academic article
2020
-
Niyonzima, Nathalie;
Bakke, Siril Skaret;
Gregersen, Ida;
Holm, Sverre;
Sandanger, Øystein;
Orrem, Hilde Lang.
(2020)
Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis.
EBioMedicine
Academic article
2019
-
Kannan, Nisha;
Lai, Yi-Pin;
Haug, Markus;
Lilleness, Mary Kathleen;
Bakke, Siril Skaret;
Marstad, Anne.
(2019)
Genetic Variation/Evolution and Differential Host Responses
Resulting from In-Patient Adaptation of Mycobacterium avium.
Infection and Immunity
Academic article
-
Pilely, Katrine;
Bakke, Siril Skaret;
Palarasah, Yaseelan;
Skjoedt, Mikkel-Ole;
Bartels, Emil D.;
Espevik, Terje.
(2019)
Alpha-cyclodextrin inhibits cholesterol crystal-induced complement-mediated inflammation: A potential new compound for treatment of atherosclerosis.
Atherosclerosis
Academic article
-
Christensen, Jacob J.;
Bakke, Siril Skaret;
Ulven, Stine Marie;
Retterstøl, Kjetil;
Henriksen, Tore;
Bollerslev, Jens.
(2019)
Serum Omega-6 Fatty Acids and Immunology-Related Gene Expression in Peripheral Blood Mononuclear Cells: A Cross-Sectional Analysis in Healthy Children.
Molecular Nutrition & Food Research
Academic article
-
Narverud, Ingunn;
Christensen, Jacob J.;
Bakke, Siril Skaret;
Ulven, Stine Marie;
Rundblad, Amanda;
Aukrust, Pål.
(2019)
Profiling of immune-related gene expression in children with familial hypercholesterolaemia.
Journal of Internal Medicine
Academic article
-
Lund, Jenny;
Ouwens, D. Margriet;
Wettergreen, Marianne;
Bakke, Siril Skaret;
Thoresen, G. Hege;
Aas, Vigdis.
(2019)
Increased glycolysis and higher lactate production in hyperglycemic myotubes.
Cells
Academic article
2018
-
Løvsletten, Nils Gunnar;
Bakke, Siril Skaret;
Kase, Eili Tranheim;
Ouwens, D. Margriet;
Thoresen, G. Hege;
Rustan, Arild.
(2018)
Increased triacylglycerol - Fatty acid substrate cycling in human skeletal muscle cells exposed to eicosapentaenoic acid.
PLOS ONE
Academic article
2017
-
Bakke, Siril Skaret;
Aune, Marie Hjelmseth;
Niyonzima, Nathalie;
Pilely, Katrine;
Ryan, Liv;
Skjelland, Mona.
(2017)
Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation.
Journal of Immunology
Academic article
-
Feng, Yuan Zeng;
Lund, Jenny;
Li, Yuchuan;
Knabenes, Irlin;
Bakke, Siril Skaret;
Kase, Eili Tranheim.
(2017)
Loss of perilipin 2 in cultured myotubes enhances lipolysis and redirects the metabolic energy balance from glucose oxidation towards fatty acid oxidation.
Journal of Lipid Research
Academic article
2016
-
Zimmer, Sebastian;
Grebe, Alena;
Bakke, Siril Skaret;
Bode, Niklas;
Halvorsen, Bente;
Ulas, Thomas.
(2016)
Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming.
Science Translational Medicine
Academic article
-
Pilely, Katrine;
Rosbjerg, Anne;
Genster, Ninette;
Gál, Peter;
Pál, Gábor;
Halvorsen, Bente.
(2016)
Cholesterol crystals activate the lectin complement pathway via ficolin-2 and mannose-binding lectin: Implications for the progression of atherosclerosis.
Journal of Immunology
Academic article
2015
-
Feng, Yuan Zeng;
Nikolic, Natasa;
Bakke, Siril Skaret;
Kase, Eili Tranheim;
Guderud, Kari;
Hjelmesæth, Jøran.
(2015)
Myotubes from lean and severely obese subjects with and without type 2 diabetes respond differently to an in vitro model of exercise.
American Journal of Physiology - Cell Physiology
Academic article
-
Kase, Eili Tranheim;
Feng, Yuan Zeng;
Badin, Pierre-Marie;
Bakke, Siril Skaret;
Laurens, C;
Coue, M.
(2015)
Primary defects in lipolysis and insulin action in skeletal muscle cells from type 2 diabetic individuals.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
Academic article
-
Bakke, Siril Skaret;
Feng, Yuan Zeng;
Nikolic, Natasa;
Kase, Eili Tranheim;
Moro, Cedric;
Stensrud, Camilla.
(2015)
Myotubes from Severely Obese Type 2 Diabetic Subjects Accumulate Less Lipids and Show Higher Lipolytic Rate than Myotubes from Severely Obese Non-Diabetic Subjects.
PLOS ONE
Academic article
-
Niyonzima, Nathalie;
Samstad, Eivind;
Aune, Marie Hjelmseth;
Ryan, Liv;
Bakke, Siril Skaret;
Rokstad, Anne Mari.
(2015)
Reconstituted high-density lipoprotein attenuates cholesterol crystal-induced inflammatory responses by reducing complement activation.
Journal of Immunology
Academic article
2014
-
Samstad, Eivind;
Niyonzima, Nathalie;
Nymo, Stig Haugset;
Aune, Marie Hjelmseth;
Ryan, Liv;
Bakke, Siril Skaret.
(2014)
Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release.
Journal of Immunology
Academic article
-
Feng, Yuan Zeng;
Nikolic, Natasa;
Bakke, Siril Skaret;
Boekschoten, Mark V.;
Kersten, Sander;
Kase, Eili Tranheim.
(2014)
PPARδ activation in human myotubes increases mitochondrial fatty acid oxidative capacity and reduces glucose utilization by a switch in substrate preference.
Archives of Physiology and Biochemistry
Academic article
2013
-
Bakke, Siril Skaret.
(2013)
Regulation of energy metabolism in human skeletal muscle cells. Effects of fatty acids, in vitro exercise and extreme obesity with and without type 2 diabetes.
Akademika forlag
Series of dissertations submitted to the Faculty of Mathematics and Natural Sciences, University of Oslo. (1319)
Doctoral dissertation
-
Kase, Eili Tranheim;
Nikolic, Natasa;
Bakke, Siril Skaret;
Bogen, Kaja Kamilla;
Aas, Vigdis;
Thoresen, G. Hege.
(2013)
Remodelling of oxidative energy metabolism by galactose improves glucose handling and metabolic switching in human skeletal muscle cells.
PLOS ONE
Academic article
-
Aas, Vigdis;
Bakke, Siril Skaret;
Feng, Yuan Zeng;
Kase, Eili Tranheim;
Jensen, Jørgen;
Bajpeyi, Sudip.
(2013)
Are cultured human myotubes far from home?.
Cell and Tissue Research
Academic literature review
2012
-
Gjelstad, Ingrid Merethe Fange;
Haugen, Fred;
Gulseth, Hanne Løvdal;
Norheim, Frode;
Jans, Annike;
Bakke, Siril Skaret.
(2012)
Expression of perilipins in human skeletal muscle in vitro and in vivo in relation to diet, exercise and energy balance.
Archives of Physiology and Biochemistry
Academic article
-
Bakke, Siril Skaret;
Moro, Cedric;
Nikolic, Natasa;
Hessvik, Nina Pettersen;
Badin, Pierre-Marie;
Lauvhaug, Line.
(2012)
Palmitic acid follows a different metabolic pathway than oleic acid in human skeletal muscle cells; lower lipolysis rate despite an increased level of adipose triglyceride lipase.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
Academic article
-
Nikolic, Natasa;
Bakke, Siril Skaret;
Kase, Eili Tranheim;
Rudberg, Ida;
Halle, Ingeborg Flo;
Rustan, Arild.
(2012)
Electrical Pulse Stimulation of Cultured Human Skeletal Muscle Cells as an In Vitro Model of Exercise.
PLOS ONE
Academic article
-
Bakke, Siril Skaret;
Damlien, Lisbeth;
Hjelmesæth, Jøran;
Aas, Vigdis.
(2012)
Motstand mot insulinresistens? Hvorfor er noen pasienter med sykelig overvekt beskyttet mot insulinresistens og type 2-diabetes?.
Diabetesforum
Popular scientific article
-
Bakke, Siril Skaret.
(2012)
Molekylære mekanismer ved fedme og type 2 diabetes.
NBS-nytt
Article in business/trade/industry journal
-
Hessvik, Nina Pettersen;
Bakke, Siril Skaret;
Smith, Robert;
Ravna, aina westrheim;
Sylte, Ingebrigt;
Rustan, Arild.
(2012)
The liver X receptor modulator 22(S)-hydroxycholesterol exerts cell-type specific effects on lipid and glucose metabolism.
Journal of Steroid Biochemistry and Molecular Biology
Academic article
-
Bakke, Siril Skaret;
Kase, Eili Tranheim.
(2012)
Energimetabolisme i skjelettmuskelceller relatert til insulinresistens og type 2-diabetes.
BestPractice Diabetes
Article in business/trade/industry journal
2011
-
Thoresen, G. Hege;
Hessvik, Nina Pettersen;
Bakke, Siril Skaret;
Aas, Vigdis;
Rustan, Arild.
(2011)
Metabolic switching of human skeletal muscle cells in vitro.
Prostaglandins, Leukotrienes and Essential Fatty Acids
Academic article
2010
-
Hessvik, Nina Pettersen;
Bakke, Siril Skaret;
Fredriksson, K;
Boekschoten, MV;
Fjørkenstad, Anne;
Koster, Gerbrand.
(2010)
Metabolic switching of human myotubes is improved by n-3 fatty acids.
Journal of Lipid Research
Academic article
-
Corpeleijn, Eva;
Hessvik, Nina Pettersen;
Bakke, Siril Skaret;
Levin, K;
Blaak, Ellen E.;
Thoresen, G. Hege.
(2010)
Oxidation of intramyocellular lipids is dependent on mitochondrial function and the availability of extracellular fatty acids.
American Journal of Physiology. Endocrinology and Metabolism
Academic article
Journal publications
-
Nilsen, Kaja Elisabeth;
Zhang, Boyao;
Skjesol, Astrid;
Ryan, Liv;
Vagle, Hilde;
Bøe, Maren Helene.
(2023)
Peptide derived from SLAMF1 prevents TLR4-mediated inflammation in vitro and in vivo.
Life Science Alliance (LSA)
Academic article
-
Mundal, Siv Boon;
Rakner, Johanne Johnsen;
Silva, Gabriela;
Gierman, Lobke;
Austdal, Marie;
Basnet, Purusotam.
(2022)
Divergent Regulation of Decidual Oxidative-Stress Response by NRF2 and KEAP1 in Preeclampsia with and without Fetal Growth Restriction.
International Journal of Molecular Sciences
Academic article
-
Niyonzima, Nathalie;
Bakke, Siril Skaret;
Gregersen, Ida;
Holm, Sverre;
Sandanger, Øystein;
Orrem, Hilde Lang.
(2020)
Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis.
EBioMedicine
Academic article
-
Kannan, Nisha;
Lai, Yi-Pin;
Haug, Markus;
Lilleness, Mary Kathleen;
Bakke, Siril Skaret;
Marstad, Anne.
(2019)
Genetic Variation/Evolution and Differential Host Responses
Resulting from In-Patient Adaptation of Mycobacterium avium.
Infection and Immunity
Academic article
-
Pilely, Katrine;
Bakke, Siril Skaret;
Palarasah, Yaseelan;
Skjoedt, Mikkel-Ole;
Bartels, Emil D.;
Espevik, Terje.
(2019)
Alpha-cyclodextrin inhibits cholesterol crystal-induced complement-mediated inflammation: A potential new compound for treatment of atherosclerosis.
Atherosclerosis
Academic article
-
Christensen, Jacob J.;
Bakke, Siril Skaret;
Ulven, Stine Marie;
Retterstøl, Kjetil;
Henriksen, Tore;
Bollerslev, Jens.
(2019)
Serum Omega-6 Fatty Acids and Immunology-Related Gene Expression in Peripheral Blood Mononuclear Cells: A Cross-Sectional Analysis in Healthy Children.
Molecular Nutrition & Food Research
Academic article
-
Narverud, Ingunn;
Christensen, Jacob J.;
Bakke, Siril Skaret;
Ulven, Stine Marie;
Rundblad, Amanda;
Aukrust, Pål.
(2019)
Profiling of immune-related gene expression in children with familial hypercholesterolaemia.
Journal of Internal Medicine
Academic article
-
Lund, Jenny;
Ouwens, D. Margriet;
Wettergreen, Marianne;
Bakke, Siril Skaret;
Thoresen, G. Hege;
Aas, Vigdis.
(2019)
Increased glycolysis and higher lactate production in hyperglycemic myotubes.
Cells
Academic article
-
Løvsletten, Nils Gunnar;
Bakke, Siril Skaret;
Kase, Eili Tranheim;
Ouwens, D. Margriet;
Thoresen, G. Hege;
Rustan, Arild.
(2018)
Increased triacylglycerol - Fatty acid substrate cycling in human skeletal muscle cells exposed to eicosapentaenoic acid.
PLOS ONE
Academic article
-
Bakke, Siril Skaret;
Aune, Marie Hjelmseth;
Niyonzima, Nathalie;
Pilely, Katrine;
Ryan, Liv;
Skjelland, Mona.
(2017)
Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation.
Journal of Immunology
Academic article
-
Feng, Yuan Zeng;
Lund, Jenny;
Li, Yuchuan;
Knabenes, Irlin;
Bakke, Siril Skaret;
Kase, Eili Tranheim.
(2017)
Loss of perilipin 2 in cultured myotubes enhances lipolysis and redirects the metabolic energy balance from glucose oxidation towards fatty acid oxidation.
Journal of Lipid Research
Academic article
-
Zimmer, Sebastian;
Grebe, Alena;
Bakke, Siril Skaret;
Bode, Niklas;
Halvorsen, Bente;
Ulas, Thomas.
(2016)
Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming.
Science Translational Medicine
Academic article
-
Pilely, Katrine;
Rosbjerg, Anne;
Genster, Ninette;
Gál, Peter;
Pál, Gábor;
Halvorsen, Bente.
(2016)
Cholesterol crystals activate the lectin complement pathway via ficolin-2 and mannose-binding lectin: Implications for the progression of atherosclerosis.
Journal of Immunology
Academic article
-
Feng, Yuan Zeng;
Nikolic, Natasa;
Bakke, Siril Skaret;
Kase, Eili Tranheim;
Guderud, Kari;
Hjelmesæth, Jøran.
(2015)
Myotubes from lean and severely obese subjects with and without type 2 diabetes respond differently to an in vitro model of exercise.
American Journal of Physiology - Cell Physiology
Academic article
-
Kase, Eili Tranheim;
Feng, Yuan Zeng;
Badin, Pierre-Marie;
Bakke, Siril Skaret;
Laurens, C;
Coue, M.
(2015)
Primary defects in lipolysis and insulin action in skeletal muscle cells from type 2 diabetic individuals.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
Academic article
-
Bakke, Siril Skaret;
Feng, Yuan Zeng;
Nikolic, Natasa;
Kase, Eili Tranheim;
Moro, Cedric;
Stensrud, Camilla.
(2015)
Myotubes from Severely Obese Type 2 Diabetic Subjects Accumulate Less Lipids and Show Higher Lipolytic Rate than Myotubes from Severely Obese Non-Diabetic Subjects.
PLOS ONE
Academic article
-
Niyonzima, Nathalie;
Samstad, Eivind;
Aune, Marie Hjelmseth;
Ryan, Liv;
Bakke, Siril Skaret;
Rokstad, Anne Mari.
(2015)
Reconstituted high-density lipoprotein attenuates cholesterol crystal-induced inflammatory responses by reducing complement activation.
Journal of Immunology
Academic article
-
Samstad, Eivind;
Niyonzima, Nathalie;
Nymo, Stig Haugset;
Aune, Marie Hjelmseth;
Ryan, Liv;
Bakke, Siril Skaret.
(2014)
Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release.
Journal of Immunology
Academic article
-
Feng, Yuan Zeng;
Nikolic, Natasa;
Bakke, Siril Skaret;
Boekschoten, Mark V.;
Kersten, Sander;
Kase, Eili Tranheim.
(2014)
PPARδ activation in human myotubes increases mitochondrial fatty acid oxidative capacity and reduces glucose utilization by a switch in substrate preference.
Archives of Physiology and Biochemistry
Academic article
-
Kase, Eili Tranheim;
Nikolic, Natasa;
Bakke, Siril Skaret;
Bogen, Kaja Kamilla;
Aas, Vigdis;
Thoresen, G. Hege.
(2013)
Remodelling of oxidative energy metabolism by galactose improves glucose handling and metabolic switching in human skeletal muscle cells.
PLOS ONE
Academic article
-
Aas, Vigdis;
Bakke, Siril Skaret;
Feng, Yuan Zeng;
Kase, Eili Tranheim;
Jensen, Jørgen;
Bajpeyi, Sudip.
(2013)
Are cultured human myotubes far from home?.
Cell and Tissue Research
Academic literature review
-
Gjelstad, Ingrid Merethe Fange;
Haugen, Fred;
Gulseth, Hanne Løvdal;
Norheim, Frode;
Jans, Annike;
Bakke, Siril Skaret.
(2012)
Expression of perilipins in human skeletal muscle in vitro and in vivo in relation to diet, exercise and energy balance.
Archives of Physiology and Biochemistry
Academic article
-
Bakke, Siril Skaret;
Moro, Cedric;
Nikolic, Natasa;
Hessvik, Nina Pettersen;
Badin, Pierre-Marie;
Lauvhaug, Line.
(2012)
Palmitic acid follows a different metabolic pathway than oleic acid in human skeletal muscle cells; lower lipolysis rate despite an increased level of adipose triglyceride lipase.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
Academic article
-
Nikolic, Natasa;
Bakke, Siril Skaret;
Kase, Eili Tranheim;
Rudberg, Ida;
Halle, Ingeborg Flo;
Rustan, Arild.
(2012)
Electrical Pulse Stimulation of Cultured Human Skeletal Muscle Cells as an In Vitro Model of Exercise.
PLOS ONE
Academic article
-
Bakke, Siril Skaret;
Damlien, Lisbeth;
Hjelmesæth, Jøran;
Aas, Vigdis.
(2012)
Motstand mot insulinresistens? Hvorfor er noen pasienter med sykelig overvekt beskyttet mot insulinresistens og type 2-diabetes?.
Diabetesforum
Popular scientific article
-
Bakke, Siril Skaret.
(2012)
Molekylære mekanismer ved fedme og type 2 diabetes.
NBS-nytt
Article in business/trade/industry journal
-
Hessvik, Nina Pettersen;
Bakke, Siril Skaret;
Smith, Robert;
Ravna, aina westrheim;
Sylte, Ingebrigt;
Rustan, Arild.
(2012)
The liver X receptor modulator 22(S)-hydroxycholesterol exerts cell-type specific effects on lipid and glucose metabolism.
Journal of Steroid Biochemistry and Molecular Biology
Academic article
-
Bakke, Siril Skaret;
Kase, Eili Tranheim.
(2012)
Energimetabolisme i skjelettmuskelceller relatert til insulinresistens og type 2-diabetes.
BestPractice Diabetes
Article in business/trade/industry journal
-
Thoresen, G. Hege;
Hessvik, Nina Pettersen;
Bakke, Siril Skaret;
Aas, Vigdis;
Rustan, Arild.
(2011)
Metabolic switching of human skeletal muscle cells in vitro.
Prostaglandins, Leukotrienes and Essential Fatty Acids
Academic article
-
Hessvik, Nina Pettersen;
Bakke, Siril Skaret;
Fredriksson, K;
Boekschoten, MV;
Fjørkenstad, Anne;
Koster, Gerbrand.
(2010)
Metabolic switching of human myotubes is improved by n-3 fatty acids.
Journal of Lipid Research
Academic article
-
Corpeleijn, Eva;
Hessvik, Nina Pettersen;
Bakke, Siril Skaret;
Levin, K;
Blaak, Ellen E.;
Thoresen, G. Hege.
(2010)
Oxidation of intramyocellular lipids is dependent on mitochondrial function and the availability of extracellular fatty acids.
American Journal of Physiology. Endocrinology and Metabolism
Academic article
Report
-
Bakke, Siril Skaret.
(2013)
Regulation of energy metabolism in human skeletal muscle cells. Effects of fatty acids, in vitro exercise and extreme obesity with and without type 2 diabetes.
Akademika forlag
Series of dissertations submitted to the Faculty of Mathematics and Natural Sciences, University of Oslo. (1319)
Doctoral dissertation
Outreach
2024
-
PosterNilsen, Kaja Elisabeth; Skjesol, Astrid; Bakke, Siril Skaret; Ryan, Liv; Stenvik, Jørgen; Espevik, Terje. (2024) SLAMF1-derived peptide inhibits signaling initiated by endosomal Toll-like receptors. TOLL 2024 , Rotterdam 2024-04-17 - 2024-04-20
2023
-
PosterNilsen, Kaja Elisabeth; Zhang, Boyao; Skjesol, Astrid; Bakke, Siril Skaret; Gravastrand, Caroline Saugestad; Ryan, Liv. (2023) SLAMF1-derived peptide could limit the inflammation mediated by several Toll-like receptors. 18th International Conference on Innate Immunity , Chania 2023-05-31 - 2023-06-05
2020
-
Academic lectureNarverud, Ingunn; Christensen, Jacob Juel; Bakke, Siril Skaret; Ulven, Stine Marie; Rundblad, Amanda; Aukrust, Pål. (2020) Profiling of immune‐related gene expression in children with familial hypercholesterolaemia. Department of Nutrition Throne-Holst Stiftelse Festaften , Department of Nutrition/Zoom 2020-10-15 - 2020-10-15
2018
-
PosterChristensen, Jacob J.; Bakke, Siril Skaret; Ulven, Stine Marie; Retterstøl, Kjetil; Henriksen, Tore; Bollerslev, Jens. (2018) Association between omega 6 fatty acids and inflammation-related gene expression in PBMCs: a cross-sectional study in healthy children. Scandinavian society of atherosclerosis Research Scandinavian society of atherosclerosis Research , Humlebæk 2018-04-11 - 2018-04-14
2017
-
LectureEspevik, Terje; Niyonzima, Nathalie; Bakke, Siril Skaret; Halvorsen, Bente; Gregersen, Ida; Skjelland, Mona. (2017) Systemic- and local complement activation controls the NLRP3 inflammasome pathway in patients with atherosclerosis. Lecture 2017-09-09 - 2017-09-12
-
PosterBakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Pilely, Katrine; Ryan, Liv; Skjelland, Mona. (2017) Cyclodextrin inhibits CC-induced complement activation. the 16th European Meeting on Complement in Human Disease 2017-09-08 - 2017-09-12
2016
-
PosterBakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Ryan, Liv; Pilely, Katrine; Garred, Peter. (2016) β- CYCLODEXTRIN REDUCES CHOLESTEROL CRYSTAL-INDUCED INFLAMMATION THROUGH MODULATING COMPLEMENT ACTIVATION . CEMIR, NTNU Conference on Molecular Mechanisms of Inflammation , Trondheim 2016-05-30 - 2016-06-02
2015
-
PosterAune, Marie Hjelmseth; Niyonzima, Nathalie; Samstad, Eivind; Bakke, Siril Skaret; Ryan, Liv; Rokstad, Anne Mari. (2015) Crystalline cholesterol is found in atherosclerotic plaques and induces complement mediated inflammation. 15th European Meeting on Complement in Human Disease 2015-06-27 - 2015-06-30
-
PosterBakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Ryan, Liv; Damås, Jan Kristian; Latz, Eicke. (2015) β- CYCLODEXTRIN REDUCES CHOLESTEROL CRYSTAL-INDUCED INFLAMMATION THROUGH MODULATING COMPLEMENT ACTIVATION. Toll 2015 2015-09-30 - 2015-10-03
-
PosterBakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Ryan, Liv; Damås, Jan Kristian; Mollnes, Tom Eirik. (2015) Beta-cyclodextrin reduces cholesterol crystal-induced inflammation through modulating complement activation. European Meeting on Complement in Human Disease 2015-06-27 - 2015-06-30
-
LectureAune, Marie Hjelmseth; Niyonzima, Nathalie; Samstad, Eivind; Nymo, Stig; Ryan, Liv; Bakke, Siril Skaret. (2015) Cholesterol crystals activate the complement system to induce crystal phagocytosis and inflammation. The International Atherosclerosis Society 17TH International Congress on Atherosclerosis 2015 , Amsterdam 2015-05-22 - 2015-05-26
2014
-
Academic lectureBakke, Siril Skaret. (2014) β-cyclodextrin inhibits cholesterol crystal-induced inflammatory responses in human peripheral blood mononuclear cells (PBMC). NBS Norsk Biokjemisk Selskap Kontaktmøte , Røros 2014-01-23 - 2014-01-25
2012
-
Academic lectureBakke, Siril Skaret. (2012) Altered energy metabolism in skeletal muscle cells derived from morbidly obese donors. Diabetesforbundet Stipendiatseminar , Gardemoen 2012-03-12 - 2012-03-13
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PosterBakke, Siril Skaret; Nikolic, Natasa; Rustan, Arild; Hjelmesæth, Jøran; Thoresen, G. Hege; Aas, Vigdis. (2012) Altered energy metabolism in skeletal muscle cells derived from morbidly obese donors. Keystone Genetic and Molecular Basis of Obesity and Body Weight Regulation 2012-01-29 - 2012-02-03
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PosterBakke, Siril Skaret; Nikolic, Natasa; Rustan, Arild; Hjelmesæth, Jøran; Thoresen, G. Hege; Aas, Vigdis. (2012) ALTERED ENERGY METABOLISM IN SKELETAL MUSCLE CELLS DERIVED FROM MORBIDLY OBESE INDIVIDUALS. The European Association for the Study of Obesity European Congress on Obesity (ECO) , Lyon 2012-05-09 - 2012-05-12
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Academic lectureAas, Vigdis; Bakke, Siril Skaret; Nikolic, Natasa; Hjelmesæth, Jøran; Thoresen, G. Hege; Rustan, Arild. (2012) Altered energy metabolism in skeletal muscle cells derived from morbidly obese subjects. European Association for the Study of Diabetes EASD 48th Meeting , Berlin 2012-10-01 - 2012-10-05
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PosterBakke, Siril Skaret; Feng, Yuan Zeng; Rustan, Arild; Hjelmesæth, Jøran; Thoresen, G. Hege; Aas, Vigdis. (2012) Lower lipolysis to counteract the development of type 2 diabetes mellitus - evidence from myotubes established from extremely obese subjects. Norges Diabetesforbund Diabetesforskningskonferansen 2012 , Gardermoen 2012-11-15 - 2012-11-16
2011
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PosterHalle, Ingeborg F.; Nikolic, Natasa; Bakke, Siril Skaret; Thoresen, G. Hege; Rustan, Arild; Aas, Vigdis. (2011) Electrical pulse stimulation of cultured human skeletal muscle cells as a model of exercise in vitro. Norsk selskap for farmakologi og toksikologi Farmakologisk Vintermøte 2011 , Beitostølen 2011-01-27 - 2011-01-30
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PosterDamlien, Lisbeth; Bakke, Siril Skaret; Rustan, Arild C.; Hjelmesæth, Jøran; Sandbu, Rune; Aas, Vigdis. (2011) Why are some obese individuals less susceptible to evolve insulin resistance and type 2 diabetes?. Norsk selskap for farmakologi og toksikologi Farmakologisk Vintermøte 2011 , Beitostølen 2011-01-27 - 2011-01-30
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PosterLauvhaug, Line; Bakke, Siril Skaret; Thoresen, G. Hege; Rustan, Arild. (2011) Different handling of oleic, palmitic, linoleic and eicosapentaenoic acids in cultured human skeletal muscle cells. NSFT Farmakologisk Vintermøte , Beitostølen 2011-01-27 - 2011-01-30
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PosterBakke, Siril Skaret; Nikolic, Natasa; Moro, Cedric; Lauvhaug, Line; Hessvik, Nina Pettersen; Thoresen, G. Hege. (2011) Different handling of palmitic acid and oleic acid in human skeletal muscle cells. The International Conference on the Bioscience of Lipids 2011-08-31 - 2011-09-03
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PosterBakke, Siril Skaret; Nikolic, Natasa; Moro, Cedric; Lauvhaug, Line; Hessvik, Nina Pettersen; Thoresen, G. Hege. (2011) DIFFERENT HANDLING OF PALMITIC ACID AND OLEIC ACID IN HUMAN SKELETAL MUSCLE CELLS. Norsk Farmasøytisk Selskap Farmasidagene 2011 , Oslo 2011-11-02 - 2011-11-04
2010
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PosterNikolic, Natasa; Bakke, Siril Skaret; Thoresen, G. Hege; Rustan, Arild; Aas, Vigdis. (2010) Chronic electrical pulse stimulation of cultured human skeletal muscle cells as an in vitro model of exercise. Norsk Farmasøytisk Selskap Farmasidager 2010 , Oslo 2010-10-28 - 2010-10-30
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Academic lectureNikolic, Natasa; Bakke, Siril Skaret; Thoresen, G. Hege; Rustan, Arild; Aas, Vigdis. (2010) Energimetabolismen i humane skjelettmuskelceller - Utvikling av in vitro treningsmodell. Norsk Farmasøytisk Selskap Farmasidager 2010 , Oslo 2010-10-28 - 2010-10-30
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PosterNikolic, Natasa; Bakke, Siril Skaret; Thoresen, G. Hege; Rustan, Arild; Aas, Vigdis. (2010) Chronic electrical pulse stimulation of cultured human skeletal muscle cells as an in vitro model of exercise. The European Nutrigenomics Organization (NUGO), FDA INCON International Conference on Nutrigenomics , Guaruja SP 2010-09-26 - 2010-09-29
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PosterBakke, Siril Skaret; Hessvik, Nina Pettersen; Thoresen, G. Hege; Rustan, Arild. (2010) HANDLING OF PALMITIC ACID AND OLEIC ACID IN HUMAN SKELETAL MUSCLE CELLS. INCON International Conference on Nutrigenomics 2010-09-26 - 2010-09-30
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Academic lectureBakke, Siril Skaret; Hessvik, Nina Pettersen; Thoresen, G. Hege; Rustan, Arild. (2010) The impact of the n-3 fatty acid eicosapentaenoic acid (EPA) on metabolic switching in human skeletal muscle cells. Norsk Farmasøytisk selskap Farmasidagene 2010-10-28 - 2010-10-30
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PosterHessvik, Nina Pettersen; Bakke, Siril Skaret; Thoresen, G. Hege; Rustan, Arild; Kase, Eili Tranheim. (2010) Effects of 22-S-hydroxycholesterol (a liver X receptor modulator) on Lipid Metabolism. American Diabetes Association American Diabetes Association Scientific Sessions 2010-06-25 - 2010-06-29
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Academic lectureBakke, Siril Skaret. (2010) Regulation of intramyocellular lipids in relation to skeletal muscle insulin resistance. Diabetesforbundet Diabetes stipendiatkonferansen 2010-03-23 - 2010-03-24
2009
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PosterBakke, Siril Skaret; Hessvik, Nina Pettersen; Fjørkenstad, Anne; Koster, Gerbrand; Rustan, Arild; Thoresen, G. Hege. (2009) Eicosapentaenoic acid improves metabolic switching of human myotubes. The Norwegian Molecular Imaging Consortium NorMIC 2009-11-12 - 2009-11-13