Siver Andreas Moestue

About

I earned my PhD at the Norwegian University of Science and Technology (NTNU), and am now a research professor at the Dept. of Clinical and Molecular Medicine. Trained a MSc. Pharm at the University of Oslo, I started my career as a preclinical researcher in GE Healthcare. Here, I was involved in development of molecularly targeted contrast agents for SPECT/PET, and development of the Sonazoid® microbubble for diagnostic ultrasound imaging of liver cancer. In my current research, I study the role of metabolism in cancer, with focus on diagnostic and therapeutic applications in breast cancer. In an ongoing project funded by the Norwegian Research Council, I study the effect drugs inhibiting the metabolic enzyme cPLA2 in an aggressive subtype of breast cancer. Realizing the importance of the tumor microenvironment, I also have established activities in the interface between immunology, metabolism and metastasis.

Publications

2024

Quinsgaard, Ellen Marie Botne; Korsnes, Monica Suarez; Korsnes, Reinert; Moestue, Siver Andreas. (2024) Single-cell tracking as a tool for studying EMT-phenotypes. Experimental Cell Research
Academic article

2023

Giampà , Marco; Andersen, Maria Karoline; Krossa, Sebastian; Denti, Vanna; Smith, Andrew; Moestue, Siver Andreas. (2023) Visualization of Small Intact Proteins in Breast Cancer FFPE Tissue. Methods in molecular biology
Academic article

2022

Pallasaho, Satu; Gondane, Aishwarya; Kuivalainen, Anni; Girmay, Samuel; Moestue, Siver Andreas; Loda, Massimo. (2022) Castration-resistant prostate cancer cells are dependent on the high activity of CDK7. Journal of Cancer Research and Clinical Oncology
Academic article
Kemp, Wybe J. M. van der; Grinde, Maria Tunset; Malvik, Jon Olav; Laarhoven, Hanneke W. M. van; Prompers, Jeanine J.; Klomp, Dennis W. J.. (2022) Metabolic profiling of colorectal cancer organoids: A comparison between high-resolution magic angle spinning magnetic resonance spectroscopy and solution nuclear magnetic resonance spectroscopy of polar extracts. NMR in Biomedicine
Academic article

2021

Barkovskaya, Anna; Goodwin, Craig; Seip, Kotryna; Hilmarsdòttir, Bylgja; Pettersen, Solveig; Stalnecker, Clint. (2021) Detection of phenotype-specific therapeutic vulnerabilities in breast cells using a CRISPR loss-of-function screen. Molecular Oncology
Academic article
Karvelsson, Sigurdur; Sigurdsson, Arnar; Seip, Kotryna; Grinde, Maria Tunset; Wang, Qiong; Johanssson, Freyr. (2021) EMT-derived alterations in glutamine metabolism sensitize mesenchymal breast cells to mTOR inhibition. Molecular Cancer Research
Academic article
Karvelsson, Sigurdur; Wang, Qiong; Hilmarsdòttir, Bylgja; Sigurdsson, Arnar; Moestue, Siver Andreas; Mælandsmo, Gunhild Mari. (2021) Argininosuccinate lyase is a metabolic vulnerability in breast development and cancer. npj Systems Biology and Applications
Academic article
Abdollahi, Pegah; Vandsemb, Esten; Elsaadi, Samah; Røst, Lisa Marie; Yang, Rui; Hjort, Magnus Aassved. (2021) Phosphatase of Regenerating Liver-3 Regulates Cancer Cell Metabolism in Multiple Myeloma. The FASEB Journal
Academic article
Frahm, Anne; Hill, Deborah Katherine; Katsikis, Sotirios; Andreassen, Trygve; Ardenkjær-Larsen, Jan Henrik; Bathen, Tone Frost. (2021) Classification and biomarker identification of prostate tissue from TRAMP mice with hyperpolarized 13C-SIRA. Talanta: The International Journal of Pure and Applied Analytical Chemistry
Academic article
Pandya, Abhilash D.; Iversen, Tore Geir; Moestue, Siver Andreas; Grinde, Maria Tunset; Mørch, Ýrr Asbjørg; Snipstad, Sofie. (2021) Biodistribution of Poly(alkyl cyanoacrylate) Nanoparticles in Mice and Effect on Tumor Infiltration of Macrophages into a Patient-Derived Breast Cancer Xenograft. Nanomaterials
Academic article
Horatz, Kilian; Giampà, Marco; Qiao, Zhi; Moestue, Siver A.; Lissel, Franziska. (2021) Polymerization as a Strategy to Improve Small Organic Matrices for Low-Molecular-Weight Compound Analytics with MALDI MS and MALDI MS Imaging. ACS Applied Polymer Materials
Academic article
Denti, Vanna; Andersen, Maria Karoline; Smith, Andrew; Bofin, Anna M.; Nordborg, Anna; Magni, Fulvio. (2021) Reproducible lipid alterations in patient-derived breast cancer xenograft FFPE tissue identified with MALDI MSI for pre-clinical and clinical application. Metabolites
Academic article

2020

Barkovskaya, Anna; Seip, Kotryna; Prasmickaite, Lina; Mills, Ian Geoffrey; Moestue, Siver Andreas; Itkonen, Harri. (2020) Inhibition of O-GlcNAc transferase activates tumor-suppressor gene expression in tamoxifen-resistant breast cancer cells. Scientific Reports
Academic article
Selnæs, Kirsten Margrete; Krüger-Stokke, Brage; Elschot, Mattijs; Johansen, Håkon; Steen, Per Arvid; Langørgen, Sverre. (2020) Detection of recurrent prostate cancer with 18F-Fluciclovine PET/MRI. Frontiers in Oncology
Academic article

2019

Tunset, Hanna Maja; Feuerherm, Astrid Jullumstrø; Selvik, Linn-Karina M.; Johansen, Berit; Moestue, Siver Andreas. (2019) Cytosolic Phospholipase A2 Alpha Regulates TLR Signaling and Migration in Metastatic 4T1 Cells. International Journal of Molecular Sciences
Academic article
Pettersen, Kristine; Andersen, Sonja Benedikte; Veen, Anna van der; Nonstad, Unni; Hatakeyema, Shinji; Lambert, Christian. (2019) Autocrine activin A signalling in ovarian cancer cells regulates secretion of interleukin 6, autophagy, and cachexia. Journal of Cachexia, Sarcopenia and Muscle
Academic article
Kim, Jana; Moestue, Siver Andreas; Bathen, Tone Frost; Kim, Eugene. (2019) R2* Relaxation Affects Pharmacokinetic Analysis of Dynamic Contrast-Enhanced MRI in Cancer and Underestimates Treatment Response at 7 T. Tomography
Academic article
Chiorazzo, MG; Tunset, Hanna Maja; Popov, Anatoliy V; Johansen, Berit; Moestue, Siver Andreas; Delikatny, EJ. (2019) Detection and Differentiation of Breast Cancer Sub-Types using a cPLA2α Activatable Fluorophore. Scientific Reports
Academic article
Grinde, Maria Tunset; Giskeødegård, Guro F.; Andreassen, Trygve; Tessem, May-Britt; Bathen, Tone Frost; Moestue, Siver Andreas. (2019) Biomarker discovery using NMR based metabolomics of tissue. Methods in molecular biology
Academic literature review
Barkovskaya, Anna; Seip, Kotryna; Hilmarsdòttir, Bylgja; Mælandsmo, Gunhild Mari; Moestue, Siver Andreas; Itkonen, Harri. (2019) O-GlcNAc Transferase Inhibition Differentially Affects Breast Cancer Subtypes. Scientific Reports
Academic article
Grinde, Maria Tunset; Hilmarsdòttir, Bylgja; Tunset, Hanna Maja; Henriksen, Ida Marie; Kim, Jana; Haugen, Mads Haugland. (2019) Glutamine to proline conversion is associated with response to glutaminase inhibition in breast cancer. Breast Cancer Research
Academic article

2018

Selnæs, Kirsten Margrete; Krüger-Stokke, Brage; Elschot, Mattijs; Willoch, Frode; Størkersen, Øystein; Sandsmark, Elise. (2018) 18F-Fluciclovine PET/MRI for preoperative lymph node staging in high-risk prostate cancer patients. European Radiology
Academic article
Euceda, Leslie R.; Andersen, Maria Karoline; Tessem, May-Britt; Moestue, Siver Andreas; Grinde, Maria Tunset; Bathen, Tone Frost. (2018) NMR-Based Prostate Cancer Metabolomics. Methods in molecular biology
Academic article
Søgaard, Caroline Danielsen; Moestue, Siver Andreas; Rye, Morten Beck; Kim, Jana; Nepal, Anala; Liabakk, Nina-Beate. (2018) APIM-peptide targeting PCNA improves the efficacy of docetaxel treatment in the TRAMP mouse model of prostate cancer. OncoTarget
Academic article
Giskeødegård, Guro F.; Madssen, Torfinn Støve; Euceda, Leslie R.; Tessem, May-Britt; Moestue, Siver Andreas; Bathen, Tone Frost. (2018) NMR-based metabolomics of biofluids in cancer. NMR in Biomedicine
Academic literature review

2017

Pettersen, Kristine; Andersen, Sonja Benedikte; Degen, Simone; Tadini, Valentina; Grosjean, Joël; Hatakeyama, Shinji. (2017) Cancer cachexia associates with a systemic autophagy-inducing activity mimicked by cancer cell-derived IL-6 trans-signaling. Scientific Reports
Academic article
Li, Pengfei; Hoppmann, Susan; Du, Ping; Li, Huiling; Evans, Paul; Moestue, Siver Andreas. (2017) Pharmacokinetics of Perfluorobutane after Intra-venous Bolus Injection of Sonazoid in Healthy Chinese Volunteers. Ultrasound in Medicine and Biology
Academic article
Euceda, Leslie R.; Hill, Deborah Katherine; Stokke, Endre Røsstad; Hatem, Rana; Botty, Rania El; Bieche, Ivan. (2017) Metabolic Response to Everolimus in Patient-Derived Triple-Negative Breast Cancer Xenografts. Journal of Proteome Research
Academic article
Elschot, Mattijs; Selnæs, Kirsten Margrete; Sandsmark, Elise; Krüger-Stokke, Brage; Størkersen, Øystein; Giskeødegård, Guro F.. (2017) Combined 18F-Fluciclovine PET/MRI shows potential for detection and characterization of high-risk prostate cancer. Journal of Nuclear Medicine
Academic article
Hill, Deborah Katherine; Heindl, Andreas; Zormpas-Petridis, Konstantinos; Collins, David J.; Euceda, Leslie R.; Rodrigues, Daniel. (2017) Non-Invasive Prostate Cancer Characterization with Diffusion-Weighted MRI: Insight from In silico Studies of a Transgenic Mouse Model. Frontiers in Oncology
Academic article
Kim, Jana; Kim, Eugene; Euceda, Leslie R.; Meyer, Dan E.; Langseth, Karina; Bathen, Tone Frost. (2017) Multiparametric Characterization of Response to Anti-angiogenic Therapy Using USPIO Contrast-enhanced MRI in Combination with Dynamic Contrast-enhanced MRI. Journal of Magnetic Resonance Imaging
Academic article
Kim, Eugene; Cebulla, Jana; Mælandsmo, Gunhild; Johansen, Berit; Moestue, Siver Andreas. (2017) Anti-angiogenic therapy affects the relationship between tumor vascular structure and function: A correlation study between micro?computed tomography angiography and dynamic contrast enhanced MRI. Magnetic Resonance in Medicine
Academic article

2016

Hill, Deborah Katherine; Kim, Eugene; Teruel, Jose Ramon; Jamin, Yann; Widerøe, Marius; Søgaard, Caroline Danielsen. (2016) Diffusion-weighted MRI for early detection and characterization of prostate cancer in the transgenic adenocarcinoma of the mouse prostate model. Journal of Magnetic Resonance Imaging
Academic article
Jia, Min; Andreassen, Trygve; Jensen, Lasse; Bathen, Tone Frost; Sinha, Indranil; Gao, Hui. (2016) Estrogen receptor α promotes breast cancer by reprogramming choline metabolism. Cancer Research
Academic article
Haukaas, Tonje Husby; Moestue, Siver Andreas; Vettukattil, Muhammad Riyas; Sitter, Beathe; Lamichhane, Santosh; Segura, Remedios. (2016) Impact of freezing delay time on tissue samples for metabolomic studies. Frontiers in Oncology
Academic article
Elschot, Mattijs; Selnæs, Kirsten Margrete; Sandsmark, Elise; Krüger-Stokke, Brage; Størkersen, Øystein; Tessem, May-Britt. (2016) A PET/MRI study towards finding the optimal [18F]Fluciclovine PET protocol for detection and characterisation of primary prostate cancer. European Journal of Nuclear Medicine and Molecular Imaging
Academic article
Kim, Eugene; Tunset, Hanna Maja; Cebulla, Jana; Vettukattil, Muhammad Riyas; Helgesen, Heidi; Feuerherm, Astrid Jullumstrø. (2016) Anti-vascular effects of the cytosolic phospholipase A2 inhibitor AVX235 in a patient-derived basal-like breast cancer model. BMC Cancer
Academic article
Itkonen, Harri; Gorad, Saurabh Sayajirao; Duveau, Damien Y.; Martin, Sara E.S.; Barkovskaya, Anna; Bathen, Tone Frost. (2016) Inhibition of O-GlcNAc transferase activity reprograms prostate cancer cell metabolism. OncoTarget
Academic article

2015

Esmaeili, Morteza; Moestue, Siver Andreas; Hamans, Bob C.; Veltien, Andor; Kristian, Alexandr; Engebråten, Olav. (2015) In vivo 31P MRSI for metabolic profiling of human breast cancer xenografts. Journal of Magnetic Resonance Imaging
Academic article
Bettum, Ingrid Johanne; Gorad, Saurabh Sayajirao; Barkovskaya, Anna; Pettersen, Solveig; Moestue, Siver Andreas; Vasiliauskaite, Kotryna. (2015) Metabolic reprogramming supports the invasive phenotype in malignant melanoma. Cancer Letters
Academic article
Gorad, Saurabh Sayajirao; Ellingsen, Christine; Bathen, Tone Frost; Mathiesen, Berit Synnøve; Moestue, Siver Andreas; Rofstad, Einar K. (2015) Identification of metastasis-associated metabolic profiles in tumors using 1H-HR-MAS-MRS. Neoplasia
Academic article
Burggraf, Jacobus; Kamerling, Ingrid; Gordon, Paul B.; Schrier, Lennecke; Kam, Marijke de; Kales, Andrea J. (2015) Detection of colorectal polyps in humans using an intravenously administered fluorescent peptide targeted against c-Met. Nature Medicine
Academic article
Cebulla, Jana; Huuse-Røneid, Else Marie; Pettersen, Kristine; Veen, Anna van der; Kim, Eugene; Andersen, Sonja. (2015) MRI Reveals the in Vivo Cellular and Vascular Response to BEZ235 in Ovarian Cancer Xenografts with Different PI3-Kinase Pathway Activity. British Journal of Cancer
Academic article

2014

Esmaeili, Morteza; Bathen, Tone Frost; Engebråten, Olav; Mælandsmo, Gunhild; Gribbestad, Ingrid S; Moestue, Siver Andreas. (2014) Quantitative 31P HR-MAS MR spectroscopy for detection of response to PI3K/mTOR inhibition in breast cancer xenografts. Magnetic Resonance in Medicine
Academic article
Grinde, Maria Tunset; Skrbo, Nirma; Moestue, Siver Andreas; Rødland, Einar Andreas; Borgan, Eldrid; Kristian, Alexandr. (2014) Interplay of choline metabolites and genes in patient-derived breast cancer xenografts. Breast Cancer Research
Academic article

2013

Moestue, Siver Andreas; Huuse, Else Marie; Lindholm, Evita Maria; Bofin, Anna M.; Engebråten, Olav; Mælandsmo, Gunhild. (2013) Low-molecular contrast agent DCE-MRI and DW-MRI in early assessment of bevacizumab treatment in breast cancer xenografts. Journal of Magnetic Resonance Imaging
Academic article
Moestue, Siver Andreas; Dam, Cornelia Gerarda; Gorad, Saurabh Sayajirao; Kristian, Alexandr; Bofin, Anna M.; Mælandsmo, Gunhild. (2013) Metabolic biomarkers for response to PI3K inhibition in basal-like breast cancer. Breast Cancer Research
Academic article
Moestue, Siver Andreas; Dam, Cornelia Gerarda; Gorad, Saurabh Sayajirao; Kristian, Alexandr; Bofin, Anna M.; Mælandsmo, Gunhild. (2013) Metabolic biomarkers for response to PI3K inhibition in basal-like breast cancer. Breast Cancer Research
Academic article
Borgan, Eldrid; Lindholm, Evita Maria; Moestue, Siver Andreas; Mælandsmo, Gunhild; Lingjærde, Ole Christian; Gribbestad, Ingrid S. (2013) Subtype-specific response to bevacizumab is reflected in the metabolome and transcriptome of breast cancer xenografts. Molecular Oncology
Academic article

2012

Huuse, Else Marie; Moestue, Siver Andreas; Lindholm, Evita Maria; Bathen, Tone Frost; Nalwoga, Hawa; Krüger, Kristi. (2012) In vivo MRI and histopathological assessment of tumor microenvironment in luminal-like and basal-like breast cancer xenografts. Journal of Magnetic Resonance Imaging
Academic article
Moestue, Siver Andreas; Giskeødegård, Guro F.; Cao, Maria Dung; Bathen, Tone Frost; Gribbestad, Ingrid S. (2012) Glycerophosphocholine (GPC) is a poorly understood biomarker in breast cancer. Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Reader opinion piece
Moestue, Siver Andreas; Flatabø, Silje; Huuse, Else Marie; Lindholm, Evita Maria; Engebraaten, Olav; Maelandsmo, Gunnhild M. (2012) Metabolic Responses to VEGF Inhibition in Patient-derived Breast Cancer Xenografts. European Journal of Cancer
Abstract
Moestue, Siver Andreas; Gribbestad, Ingrid S; Hansen, Rune. (2012) Intravascular Targets for Molecular Contrast-Enhanced Ultrasound Imaging. International Journal of Molecular Sciences
Academic literature review

2011

Moestue, Siver Andreas; Engebråten, Olav; Gribbestad, Ingrid S. (2011) Metabolic effects of signal transduction inhibition in cancer assessed by magnetic resonance spectroscopy. Molecular Oncology
Academic literature review
Moestue, Siver Andreas; Sitter, Beathe; Bathen, Tone Frost; Tessem, May-Britt; Gribbestad, Ingrid S. (2011) HR MAS MR Spectroscopy in Metabolic Characterization of Cancer. Current Topics in Medicinal Chemistry
Academic literature review
Glunde, Kristine; Jiang, Liu; Moestue, Siver Andreas; Gribbestad, Ingrid S. (2011) MRS and MRSI guidance in molecular medicine: targeting and monitoring of choline and glucose metabolism in cancer. NMR in Biomedicine
Academic literature review
Sitter, Beathe; Moestue, Siver Andreas; Bathen, Tone Frost; Gribbestad, Ingrid S. (2011) MR metabolomics i biomedisinsk forskning. Helse, Medisin, Teknikk
Article in business/trade/industry journal
Grinde, Maria Tunset; Moestue, Siver Andreas; Borgan, Eldrid; Risa, Øystein; Engebråten, Olav; Gribbestad, Ingrid S. (2011) 13C High-resolution-magic angle spinning MRS reveals differences in glucose metabolism between two breast cancer xenograft models with different gene expression patterns. NMR in Biomedicine
Academic article

2010

Moestue, Siver Andreas; Borgan, Eldrid; Huuse, Else Marie; Lindholm, Evita Maria; Sitter, Beathe; Børresen-Dale, Anne-Lise. (2010) Distinct choline metabolic profiles are associated with differences in gene expression for basal-like and luminal-like breast cancer xenograft models. BMC Cancer
Academic article

2009

Moestue, Siver Andreas; nunez, paula; Indrevoll, Bård; Healey, Andrew; Bjerke, Roger; Skotland, Tore. (2009) Whole-body section fluorescence imaging - a novel method for tissue distribution studies of fluorescent substances. Contrast Media & Molecular Imaging
Academic article

Journal publications

Quinsgaard, Ellen Marie Botne; Korsnes, Monica Suarez; Korsnes, Reinert; Moestue, Siver Andreas. (2024) Single-cell tracking as a tool for studying EMT-phenotypes. Experimental Cell Research
Academic article
Giampà , Marco; Andersen, Maria Karoline; Krossa, Sebastian; Denti, Vanna; Smith, Andrew; Moestue, Siver Andreas. (2023) Visualization of Small Intact Proteins in Breast Cancer FFPE Tissue. Methods in molecular biology
Academic article
Pallasaho, Satu; Gondane, Aishwarya; Kuivalainen, Anni; Girmay, Samuel; Moestue, Siver Andreas; Loda, Massimo. (2022) Castration-resistant prostate cancer cells are dependent on the high activity of CDK7. Journal of Cancer Research and Clinical Oncology
Academic article
Kemp, Wybe J. M. van der; Grinde, Maria Tunset; Malvik, Jon Olav; Laarhoven, Hanneke W. M. van; Prompers, Jeanine J.; Klomp, Dennis W. J.. (2022) Metabolic profiling of colorectal cancer organoids: A comparison between high-resolution magic angle spinning magnetic resonance spectroscopy and solution nuclear magnetic resonance spectroscopy of polar extracts. NMR in Biomedicine
Academic article
Barkovskaya, Anna; Goodwin, Craig; Seip, Kotryna; Hilmarsdòttir, Bylgja; Pettersen, Solveig; Stalnecker, Clint. (2021) Detection of phenotype-specific therapeutic vulnerabilities in breast cells using a CRISPR loss-of-function screen. Molecular Oncology
Academic article
Karvelsson, Sigurdur; Sigurdsson, Arnar; Seip, Kotryna; Grinde, Maria Tunset; Wang, Qiong; Johanssson, Freyr. (2021) EMT-derived alterations in glutamine metabolism sensitize mesenchymal breast cells to mTOR inhibition. Molecular Cancer Research
Academic article
Karvelsson, Sigurdur; Wang, Qiong; Hilmarsdòttir, Bylgja; Sigurdsson, Arnar; Moestue, Siver Andreas; Mælandsmo, Gunhild Mari. (2021) Argininosuccinate lyase is a metabolic vulnerability in breast development and cancer. npj Systems Biology and Applications
Academic article
Abdollahi, Pegah; Vandsemb, Esten; Elsaadi, Samah; Røst, Lisa Marie; Yang, Rui; Hjort, Magnus Aassved. (2021) Phosphatase of Regenerating Liver-3 Regulates Cancer Cell Metabolism in Multiple Myeloma. The FASEB Journal
Academic article
Frahm, Anne; Hill, Deborah Katherine; Katsikis, Sotirios; Andreassen, Trygve; Ardenkjær-Larsen, Jan Henrik; Bathen, Tone Frost. (2021) Classification and biomarker identification of prostate tissue from TRAMP mice with hyperpolarized 13C-SIRA. Talanta: The International Journal of Pure and Applied Analytical Chemistry
Academic article
Pandya, Abhilash D.; Iversen, Tore Geir; Moestue, Siver Andreas; Grinde, Maria Tunset; Mørch, Ýrr Asbjørg; Snipstad, Sofie. (2021) Biodistribution of Poly(alkyl cyanoacrylate) Nanoparticles in Mice and Effect on Tumor Infiltration of Macrophages into a Patient-Derived Breast Cancer Xenograft. Nanomaterials
Academic article
Horatz, Kilian; Giampà, Marco; Qiao, Zhi; Moestue, Siver A.; Lissel, Franziska. (2021) Polymerization as a Strategy to Improve Small Organic Matrices for Low-Molecular-Weight Compound Analytics with MALDI MS and MALDI MS Imaging. ACS Applied Polymer Materials
Academic article
Denti, Vanna; Andersen, Maria Karoline; Smith, Andrew; Bofin, Anna M.; Nordborg, Anna; Magni, Fulvio. (2021) Reproducible lipid alterations in patient-derived breast cancer xenograft FFPE tissue identified with MALDI MSI for pre-clinical and clinical application. Metabolites
Academic article
Barkovskaya, Anna; Seip, Kotryna; Prasmickaite, Lina; Mills, Ian Geoffrey; Moestue, Siver Andreas; Itkonen, Harri. (2020) Inhibition of O-GlcNAc transferase activates tumor-suppressor gene expression in tamoxifen-resistant breast cancer cells. Scientific Reports
Academic article
Selnæs, Kirsten Margrete; Krüger-Stokke, Brage; Elschot, Mattijs; Johansen, Håkon; Steen, Per Arvid; Langørgen, Sverre. (2020) Detection of recurrent prostate cancer with 18F-Fluciclovine PET/MRI. Frontiers in Oncology
Academic article
Tunset, Hanna Maja; Feuerherm, Astrid Jullumstrø; Selvik, Linn-Karina M.; Johansen, Berit; Moestue, Siver Andreas. (2019) Cytosolic Phospholipase A2 Alpha Regulates TLR Signaling and Migration in Metastatic 4T1 Cells. International Journal of Molecular Sciences
Academic article
Pettersen, Kristine; Andersen, Sonja Benedikte; Veen, Anna van der; Nonstad, Unni; Hatakeyema, Shinji; Lambert, Christian. (2019) Autocrine activin A signalling in ovarian cancer cells regulates secretion of interleukin 6, autophagy, and cachexia. Journal of Cachexia, Sarcopenia and Muscle
Academic article
Kim, Jana; Moestue, Siver Andreas; Bathen, Tone Frost; Kim, Eugene. (2019) R2* Relaxation Affects Pharmacokinetic Analysis of Dynamic Contrast-Enhanced MRI in Cancer and Underestimates Treatment Response at 7 T. Tomography
Academic article
Chiorazzo, MG; Tunset, Hanna Maja; Popov, Anatoliy V; Johansen, Berit; Moestue, Siver Andreas; Delikatny, EJ. (2019) Detection and Differentiation of Breast Cancer Sub-Types using a cPLA2α Activatable Fluorophore. Scientific Reports
Academic article
Grinde, Maria Tunset; Giskeødegård, Guro F.; Andreassen, Trygve; Tessem, May-Britt; Bathen, Tone Frost; Moestue, Siver Andreas. (2019) Biomarker discovery using NMR based metabolomics of tissue. Methods in molecular biology
Academic literature review
Barkovskaya, Anna; Seip, Kotryna; Hilmarsdòttir, Bylgja; Mælandsmo, Gunhild Mari; Moestue, Siver Andreas; Itkonen, Harri. (2019) O-GlcNAc Transferase Inhibition Differentially Affects Breast Cancer Subtypes. Scientific Reports
Academic article
Grinde, Maria Tunset; Hilmarsdòttir, Bylgja; Tunset, Hanna Maja; Henriksen, Ida Marie; Kim, Jana; Haugen, Mads Haugland. (2019) Glutamine to proline conversion is associated with response to glutaminase inhibition in breast cancer. Breast Cancer Research
Academic article
Selnæs, Kirsten Margrete; Krüger-Stokke, Brage; Elschot, Mattijs; Willoch, Frode; Størkersen, Øystein; Sandsmark, Elise. (2018) 18F-Fluciclovine PET/MRI for preoperative lymph node staging in high-risk prostate cancer patients. European Radiology
Academic article
Euceda, Leslie R.; Andersen, Maria Karoline; Tessem, May-Britt; Moestue, Siver Andreas; Grinde, Maria Tunset; Bathen, Tone Frost. (2018) NMR-Based Prostate Cancer Metabolomics. Methods in molecular biology
Academic article
Søgaard, Caroline Danielsen; Moestue, Siver Andreas; Rye, Morten Beck; Kim, Jana; Nepal, Anala; Liabakk, Nina-Beate. (2018) APIM-peptide targeting PCNA improves the efficacy of docetaxel treatment in the TRAMP mouse model of prostate cancer. OncoTarget
Academic article
Giskeødegård, Guro F.; Madssen, Torfinn Støve; Euceda, Leslie R.; Tessem, May-Britt; Moestue, Siver Andreas; Bathen, Tone Frost. (2018) NMR-based metabolomics of biofluids in cancer. NMR in Biomedicine
Academic literature review
Pettersen, Kristine; Andersen, Sonja Benedikte; Degen, Simone; Tadini, Valentina; Grosjean, Joël; Hatakeyama, Shinji. (2017) Cancer cachexia associates with a systemic autophagy-inducing activity mimicked by cancer cell-derived IL-6 trans-signaling. Scientific Reports
Academic article
Li, Pengfei; Hoppmann, Susan; Du, Ping; Li, Huiling; Evans, Paul; Moestue, Siver Andreas. (2017) Pharmacokinetics of Perfluorobutane after Intra-venous Bolus Injection of Sonazoid in Healthy Chinese Volunteers. Ultrasound in Medicine and Biology
Academic article
Euceda, Leslie R.; Hill, Deborah Katherine; Stokke, Endre Røsstad; Hatem, Rana; Botty, Rania El; Bieche, Ivan. (2017) Metabolic Response to Everolimus in Patient-Derived Triple-Negative Breast Cancer Xenografts. Journal of Proteome Research
Academic article
Elschot, Mattijs; Selnæs, Kirsten Margrete; Sandsmark, Elise; Krüger-Stokke, Brage; Størkersen, Øystein; Giskeødegård, Guro F.. (2017) Combined 18F-Fluciclovine PET/MRI shows potential for detection and characterization of high-risk prostate cancer. Journal of Nuclear Medicine
Academic article
Hill, Deborah Katherine; Heindl, Andreas; Zormpas-Petridis, Konstantinos; Collins, David J.; Euceda, Leslie R.; Rodrigues, Daniel. (2017) Non-Invasive Prostate Cancer Characterization with Diffusion-Weighted MRI: Insight from In silico Studies of a Transgenic Mouse Model. Frontiers in Oncology
Academic article
Kim, Jana; Kim, Eugene; Euceda, Leslie R.; Meyer, Dan E.; Langseth, Karina; Bathen, Tone Frost. (2017) Multiparametric Characterization of Response to Anti-angiogenic Therapy Using USPIO Contrast-enhanced MRI in Combination with Dynamic Contrast-enhanced MRI. Journal of Magnetic Resonance Imaging
Academic article
Kim, Eugene; Cebulla, Jana; Mælandsmo, Gunhild; Johansen, Berit; Moestue, Siver Andreas. (2017) Anti-angiogenic therapy affects the relationship between tumor vascular structure and function: A correlation study between micro?computed tomography angiography and dynamic contrast enhanced MRI. Magnetic Resonance in Medicine
Academic article
Hill, Deborah Katherine; Kim, Eugene; Teruel, Jose Ramon; Jamin, Yann; Widerøe, Marius; Søgaard, Caroline Danielsen. (2016) Diffusion-weighted MRI for early detection and characterization of prostate cancer in the transgenic adenocarcinoma of the mouse prostate model. Journal of Magnetic Resonance Imaging
Academic article
Jia, Min; Andreassen, Trygve; Jensen, Lasse; Bathen, Tone Frost; Sinha, Indranil; Gao, Hui. (2016) Estrogen receptor α promotes breast cancer by reprogramming choline metabolism. Cancer Research
Academic article
Haukaas, Tonje Husby; Moestue, Siver Andreas; Vettukattil, Muhammad Riyas; Sitter, Beathe; Lamichhane, Santosh; Segura, Remedios. (2016) Impact of freezing delay time on tissue samples for metabolomic studies. Frontiers in Oncology
Academic article
Elschot, Mattijs; Selnæs, Kirsten Margrete; Sandsmark, Elise; Krüger-Stokke, Brage; Størkersen, Øystein; Tessem, May-Britt. (2016) A PET/MRI study towards finding the optimal [18F]Fluciclovine PET protocol for detection and characterisation of primary prostate cancer. European Journal of Nuclear Medicine and Molecular Imaging
Academic article
Kim, Eugene; Tunset, Hanna Maja; Cebulla, Jana; Vettukattil, Muhammad Riyas; Helgesen, Heidi; Feuerherm, Astrid Jullumstrø. (2016) Anti-vascular effects of the cytosolic phospholipase A2 inhibitor AVX235 in a patient-derived basal-like breast cancer model. BMC Cancer
Academic article
Itkonen, Harri; Gorad, Saurabh Sayajirao; Duveau, Damien Y.; Martin, Sara E.S.; Barkovskaya, Anna; Bathen, Tone Frost. (2016) Inhibition of O-GlcNAc transferase activity reprograms prostate cancer cell metabolism. OncoTarget
Academic article
Esmaeili, Morteza; Moestue, Siver Andreas; Hamans, Bob C.; Veltien, Andor; Kristian, Alexandr; Engebråten, Olav. (2015) In vivo 31P MRSI for metabolic profiling of human breast cancer xenografts. Journal of Magnetic Resonance Imaging
Academic article
Bettum, Ingrid Johanne; Gorad, Saurabh Sayajirao; Barkovskaya, Anna; Pettersen, Solveig; Moestue, Siver Andreas; Vasiliauskaite, Kotryna. (2015) Metabolic reprogramming supports the invasive phenotype in malignant melanoma. Cancer Letters
Academic article
Gorad, Saurabh Sayajirao; Ellingsen, Christine; Bathen, Tone Frost; Mathiesen, Berit Synnøve; Moestue, Siver Andreas; Rofstad, Einar K. (2015) Identification of metastasis-associated metabolic profiles in tumors using 1H-HR-MAS-MRS. Neoplasia
Academic article
Burggraf, Jacobus; Kamerling, Ingrid; Gordon, Paul B.; Schrier, Lennecke; Kam, Marijke de; Kales, Andrea J. (2015) Detection of colorectal polyps in humans using an intravenously administered fluorescent peptide targeted against c-Met. Nature Medicine
Academic article
Cebulla, Jana; Huuse-Røneid, Else Marie; Pettersen, Kristine; Veen, Anna van der; Kim, Eugene; Andersen, Sonja. (2015) MRI Reveals the in Vivo Cellular and Vascular Response to BEZ235 in Ovarian Cancer Xenografts with Different PI3-Kinase Pathway Activity. British Journal of Cancer
Academic article
Esmaeili, Morteza; Bathen, Tone Frost; Engebråten, Olav; Mælandsmo, Gunhild; Gribbestad, Ingrid S; Moestue, Siver Andreas. (2014) Quantitative 31P HR-MAS MR spectroscopy for detection of response to PI3K/mTOR inhibition in breast cancer xenografts. Magnetic Resonance in Medicine
Academic article
Grinde, Maria Tunset; Skrbo, Nirma; Moestue, Siver Andreas; Rødland, Einar Andreas; Borgan, Eldrid; Kristian, Alexandr. (2014) Interplay of choline metabolites and genes in patient-derived breast cancer xenografts. Breast Cancer Research
Academic article
Moestue, Siver Andreas; Huuse, Else Marie; Lindholm, Evita Maria; Bofin, Anna M.; Engebråten, Olav; Mælandsmo, Gunhild. (2013) Low-molecular contrast agent DCE-MRI and DW-MRI in early assessment of bevacizumab treatment in breast cancer xenografts. Journal of Magnetic Resonance Imaging
Academic article
Moestue, Siver Andreas; Dam, Cornelia Gerarda; Gorad, Saurabh Sayajirao; Kristian, Alexandr; Bofin, Anna M.; Mælandsmo, Gunhild. (2013) Metabolic biomarkers for response to PI3K inhibition in basal-like breast cancer. Breast Cancer Research
Academic article
Moestue, Siver Andreas; Dam, Cornelia Gerarda; Gorad, Saurabh Sayajirao; Kristian, Alexandr; Bofin, Anna M.; Mælandsmo, Gunhild. (2013) Metabolic biomarkers for response to PI3K inhibition in basal-like breast cancer. Breast Cancer Research
Academic article
Borgan, Eldrid; Lindholm, Evita Maria; Moestue, Siver Andreas; Mælandsmo, Gunhild; Lingjærde, Ole Christian; Gribbestad, Ingrid S. (2013) Subtype-specific response to bevacizumab is reflected in the metabolome and transcriptome of breast cancer xenografts. Molecular Oncology
Academic article
Huuse, Else Marie; Moestue, Siver Andreas; Lindholm, Evita Maria; Bathen, Tone Frost; Nalwoga, Hawa; Krüger, Kristi. (2012) In vivo MRI and histopathological assessment of tumor microenvironment in luminal-like and basal-like breast cancer xenografts. Journal of Magnetic Resonance Imaging
Academic article
Moestue, Siver Andreas; Giskeødegård, Guro F.; Cao, Maria Dung; Bathen, Tone Frost; Gribbestad, Ingrid S. (2012) Glycerophosphocholine (GPC) is a poorly understood biomarker in breast cancer. Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Reader opinion piece
Moestue, Siver Andreas; Flatabø, Silje; Huuse, Else Marie; Lindholm, Evita Maria; Engebraaten, Olav; Maelandsmo, Gunnhild M. (2012) Metabolic Responses to VEGF Inhibition in Patient-derived Breast Cancer Xenografts. European Journal of Cancer
Abstract
Moestue, Siver Andreas; Gribbestad, Ingrid S; Hansen, Rune. (2012) Intravascular Targets for Molecular Contrast-Enhanced Ultrasound Imaging. International Journal of Molecular Sciences
Academic literature review
Moestue, Siver Andreas; Engebråten, Olav; Gribbestad, Ingrid S. (2011) Metabolic effects of signal transduction inhibition in cancer assessed by magnetic resonance spectroscopy. Molecular Oncology
Academic literature review
Moestue, Siver Andreas; Sitter, Beathe; Bathen, Tone Frost; Tessem, May-Britt; Gribbestad, Ingrid S. (2011) HR MAS MR Spectroscopy in Metabolic Characterization of Cancer. Current Topics in Medicinal Chemistry
Academic literature review
Glunde, Kristine; Jiang, Liu; Moestue, Siver Andreas; Gribbestad, Ingrid S. (2011) MRS and MRSI guidance in molecular medicine: targeting and monitoring of choline and glucose metabolism in cancer. NMR in Biomedicine
Academic literature review
Sitter, Beathe; Moestue, Siver Andreas; Bathen, Tone Frost; Gribbestad, Ingrid S. (2011) MR metabolomics i biomedisinsk forskning. Helse, Medisin, Teknikk
Article in business/trade/industry journal
Grinde, Maria Tunset; Moestue, Siver Andreas; Borgan, Eldrid; Risa, Øystein; Engebråten, Olav; Gribbestad, Ingrid S. (2011) 13C High-resolution-magic angle spinning MRS reveals differences in glucose metabolism between two breast cancer xenograft models with different gene expression patterns. NMR in Biomedicine
Academic article
Moestue, Siver Andreas; Borgan, Eldrid; Huuse, Else Marie; Lindholm, Evita Maria; Sitter, Beathe; Børresen-Dale, Anne-Lise. (2010) Distinct choline metabolic profiles are associated with differences in gene expression for basal-like and luminal-like breast cancer xenograft models. BMC Cancer
Academic article
Moestue, Siver Andreas; nunez, paula; Indrevoll, Bård; Healey, Andrew; Bjerke, Roger; Skotland, Tore. (2009) Whole-body section fluorescence imaging - a novel method for tissue distribution studies of fluorescent substances. Contrast Media & Molecular Imaging
Academic article

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