Terje Espevik
About
The strategy of my research group is to study the functions of the complement system, inflammasomes and Toll-like receptors in relation to signaling induced by microbes and cholesterol crystals. Our research points to new targets and strategies for treatment of inflammatory diseases. I am the director of Centre of Molecular Inflammation Research (CEMIR) which is a Centre of Excellence (https://www.ntnu.edu/cemir).
Publications
2026
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Gravastrand, Caroline Saugestad;
Yurchenko, Maria;
Kristensen, Stine;
Skjesol, Astrid;
Chen, Carmen;
Ullmann, Sindre;
Iqbal, Zunaira;
Dahlen, Karoline Ruud;
Rasheed, Kashif;
Nonstad, Unni.
(2026)
GTPase Rab11b and effector Rab11-FIP2 promote NLRP3 stability during inflammasome priming.
EMBO Journal
Academic article
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Camassa, Laura Maria Azzurra;
Elje, Elisabeth;
Shaposhnikov, Sergey;
Haugen, Kristine;
Skare, Øivind;
Espevik, Terje;
Nilsen, Asbjørn Magne;
Ryan, Liv;
Rundén-Pran, Elise;
Zienolddiny-Narui, Shan.
(2026)
Organ-specific in vitro models for prediction of hazard assessment of nanomaterials.
Toxicology in Vitro
Academic article
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Rasheed, Kashif;
Nejati Moharrami, Neda;
Tande, Erlend Bjørkøy;
Espevik, Terje;
Yurchenko, Maria;
Boyartchuk, Victor.
(2026)
Endogenous CD5L controls the metabolic and inflammatory state of human macrophages.
Frontiers in Immunology
Academic article
2025
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Nilsen, Kaja Elisabeth;
Stenvik, Jørgen;
Skjesol, Astrid;
Mestvedt, Ingvild Bergdal;
Bakke, Siril Skaret;
Giambelluca, Miriam Soledad;
Gravastrand, Caroline Saugestad;
Elamurugan, Kirusika;
Ryan, Liv;
Espevik, Terje.
(2025)
A novel TIRAP-MyD88 inhibitor blocks TLR7- and TLR8-induced type I IFN responses.
Journal of Immunology
Academic article
-
Bye, Katja Sæterhaug;
Rian, Kristin;
Ryan, Liv;
Espevik, Terje;
Anthonsen, Marit Walbye;
Yurchenko, Maria.
(2025)
The immune receptors TLR4 and SLAMF1 regulate TNF release by human metapneumovirus in human macrophages.
Frontiers in Immunology
Academic article
-
Zhang, Boyao;
Ørning, Mathias Pontus;
Lehman, Jesse W.;
Dinis, Alexandre;
Torres-Ulloa, Leslie;
Elling, Roland;
Kelliher, Michelle A.;
Bertin, John;
Proulx, Megan K.;
Goguen, Jon D..
(2025)
Raver1 links Ripk1 RNA splicing to caspase-8-mediated pyroptotic cell death, inflammation, and pathogen resistance.
Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Academic article
-
Mestvedt, Ingvild Bergdal;
Menu, Eline;
Misund, Kristine;
Slørdahl, Tobias Schmidt;
Rasheed, Kashif;
Wolowczyk, Camilla Izabel;
Hella, Hanne;
Ryan, Liv;
Standal, Therese;
Espevik, Terje.
(2025)
Novel SLAMF1-derived peptide induces apoptosis in multiple myeloma cells by targeting IRF4 transcription factor for degradation.
BioRxiv
Academic article
2024
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Olsen, Maria Belland;
Kong, Xiang Yi;
Louwe, Maria;
Lauritzen, Knut Husø;
Schanke, Ylva;
Kaasbøll, Ole Jørgen;
Attramadal, Håvard;
Øgaard, Jonas Daniel Sjøberg;
Holm, Sverre;
Aukrust, Pål.
(2024)
SLAMF1-derived peptide exhibits cardio protection after permanent left anterior descending artery ligation in mice.
Frontiers in Immunology
Academic article
-
Fageräng, Beatrice Linnea Christina;
Cyranka, Leon;
Schjalm, Camilla;
Ekholt, Karin;
Larsen, Carina Sandem;
Heinzelbecker, Julia;
Gedde-Dahl, Tobias;
Würzner, Reinhard;
Espevik, Terje;
Tjønnfjord, Geir Erland.
(2024)
The function of the complement system remains fully intact throughout the course of allogeneic stem cell transplantation.
Frontiers in Immunology
Academic article
2023
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Bjerkhaug, Aline;
Granslo, Hildegunn Norbakken;
Cavanagh, Jorunn Pauline;
Høiland, Ina Isabella;
Ludviksen, Judith K;
Lau, Corinna;
Espevik, Terje;
Mollnes, Tom Eirik;
Klingenberg, Claus Andreas.
(2023)
Dual inhibition of complement C5 and CD14 attenuates inflammation in a cord blood model.
Pediatric Research
Academic article
-
Nilsen, Kaja Elisabeth;
Zhang, Boyao;
Skjesol, Astrid;
Ryan, Liv;
Vagle, Hilde;
Bøe, Maren Helene;
Ørning, Mathias Pontus;
Kim, Hera;
Bakke, Siril Skaret;
Elamurugan, Kirusika.
(2023)
Peptide derived from SLAMF1 prevents TLR4-mediated inflammation in vitro and in vivo.
Life Science Alliance (LSA)
Academic article
-
Lentini, Germana;
Famà, Agata;
Gaetano, Giuseppe Valerio De;
Coppolino, Francesco;
Mahjoub, Ahlem Khachroub;
Ryan, Liv;
Lien, Egil;
Espevik, Terje;
Beninati, Concetta;
Teti, Giuseppe.
(2023)
Caspase-8 inhibition improves the outcome of bacterial infections in mice by promoting neutrophil activation.
Cell Reports Medicine
Academic article
2022
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Nilsen, Kaja Elisabeth;
Skjesol, Astrid;
Kojen, June Frengen;
Espevik, Terje;
Stenvik, Jørgen;
Yurchenko, Mariya.
(2022)
TIRAP/Mal Positively Regulates TLR8‐Mediated Signaling via IRF5 in Human Cells.
Biomedicines
Academic article
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Pinto, Sneha M.;
Subbannayya, Yashwanth;
Kim, Hera;
Hagen, Lars;
Górna, Maria W;
Nieminen, Anni I.;
Bjørås, Magnar;
Espevik, Terje;
Kaynov, Denis;
Kandasamy, Richard Kumaran.
(2022)
Multi-OMICs landscape of SARS-CoV-2-induced host responses in human lung epithelial cells.
iScience
Academic article
-
Johnson, Christina;
Quach, Huy Quang;
Lau, Corinna;
Ekholt, Karin;
Espevik, Terje;
Woodruff, Trent M.;
Pischke, Soeren;
Mollnes, Tom Eirik;
Nilsson, Per.
(2022)
Thrombin Differentially Modulates the Acute Inflammatory Response to Escherichia coli and Staphylococcus aureus in Human Whole Blood.
Journal of Immunology
Academic article
2021
-
Trifonov, Lena;
Yurchenko, Mariya;
Skjesol, Astrid;
Cohen, Guy;
Espevik, Terje;
Korshin, Edward E.;
Grøvdal, Lene Melsæther;
Husebye, Harald;
Gruzman, Arie.
(2021)
Benzyl-para-di-[5-methyl-4-(n-octylamino) pyrimidin-2(1H)one] as an interferon beta (IFN-β) modulator.
Molecular diversity
Academic article
-
Niyonzima, Nathalie;
Rahman, Jubayer;
Kunz, Natalie;
West, Erin;
Freiwald, Tilo;
Desai, Jigar V.;
Merle, Nicolas;
Gidon, Alexandre;
Sporsheim, Bjørnar;
Lionakis, Michail S..
(2021)
Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation.
Science immunology
Academic article
-
Kim, Hera;
Subbannayya, Yashwanth;
Humphries, Fiachra;
Skjesol, Astrid;
Pinto, Sneha M.;
Giambelluca, Miriam;
Espevik, Terje;
Fitzgerald, Katherine A.;
Kandasamy, Richard Kumaran.
(2021)
UMP-CMP kinase 2 gene expression in macrophages is dependent on the IRF3-IFNAR signaling axis.
PLOS ONE
Academic article
-
Islam, Rakibul;
Islam, Mohammad Mirazul;
Nilsson, Per H.;
Mohlin, Camilla;
Hagen, Kjersti Thorvaldsen;
Paschalis, Eleftherios I.;
Woods, Russell L.;
Bhowmick, Sabuj Chandra;
Dohlman, Claes H.;
Espevik, Terje.
(2021)
Combined blockade of complement C5 and TLR co-receptor CD14 synergistically inhibits pig-to-human corneal xenograft induced innate inflammatory responses.
Acta Biomaterialia
Academic article
2020
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Ehrnstrøm, Birgitta;
Kojen, June Frengen;
Giambelluca, Miriam;
Ryan, Liv;
Moen, Siv Helen;
Hu, Zhenyi;
Yin, Hang;
Mollnes, Tom Eirik;
Damås, Jan Kristian;
Espevik, Terje.
(2020)
TLR8 and complement C5 induce cytokine release and thrombin activation in human whole blood challenged with Gram-positive bacteria.
Journal of Leukocyte Biology
Academic article
-
Niyonzima, Nathalie;
Bakke, Siril Skaret;
Gregersen, Ida;
Holm, Sverre;
Sandanger, Øystein;
Orrem, Hilde Lang;
Sporsheim, Bjørnar;
Ryan, Liv;
Kong, Xiang Yi;
Dahl, Tuva Børresdatter.
(2020)
Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis.
EBioMedicine
Academic article
2019
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Christensen, Jacob J.;
Bakke, Siril Skaret;
Ulven, Stine Marie;
Retterstøl, Kjetil;
Henriksen, Tore;
Bollerslev, Jens;
Espevik, Terje;
Aukrust, Pål;
Halvorsen, Bente;
Holven, Kirsten Bjørklund.
(2019)
Serum Omega-6 Fatty Acids and Immunology-Related Gene Expression in Peripheral Blood Mononuclear Cells: A Cross-Sectional Analysis in Healthy Children.
Molecular Nutrition & Food Research
Academic article
-
Moen, Siv Helen;
Ehrnstrøm, Birgitta;
Kojen, June Frengen;
Yurchenko, Mariya;
Beckwith, Kai Sandvold;
Afset, Jan Egil;
Damås, Jan Kristian;
Hu, Zhenyi;
Yin, Hang;
Espevik, Terje.
(2019)
Human Toll-like receptor 8 (TLR8) is an important sensor of pyogenic bacteria, and is attenuated by cell surface TLR signaling.
Frontiers in Immunology
Academic article
-
Lunde, Ngoc Dieu Nguyen;
Gregersen, Ida;
Ueland, Thor;
Shetelig, Christian;
Holm, Sverre;
Kong, Xiang Yi;
Michelsen, Annika;
Otterdal, Kari;
Yndestad, Arne;
Broch, Kaspar.
(2019)
Legumain is upregulated in acute cardiovascular events and associated with improved outcome – potentially related to anti-inflammatory effects on macrophages.
Atherosclerosis
Academic article
-
Skjesol, Astrid;
Yurchenko, Mariya;
Bösl, Korbinian;
Gravastrand, Caroline S.;
Nilsen, Kaja Elisabeth;
Grøvdal, Lene Melsæther;
Agliano, Federica;
Patane, Francesco;
Lentini, Germana;
Kim, Hera.
(2019)
The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2.
PLoS Pathogens
Academic article
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Narverud, Ingunn;
Christensen, Jacob J.;
Bakke, Siril Skaret;
Ulven, Stine Marie;
Rundblad, Amanda;
Aukrust, Pål;
Espevik, Terje;
Bogsrud, Martin Prøven;
Retterstøl, Kjetil;
Ueland, Thor.
(2019)
Profiling of immune-related gene expression in children with familial hypercholesterolaemia.
Journal of Internal Medicine
Academic article
-
Skjeflo, Espen Waage;
Christiansen, Dorte;
Landsem, Anne;
Stenvik, Jørgen;
Woodruff, T. M.;
Espevik, Terje;
Nielsen, Erik Waage;
Mollnes, Tom Eirik.
(2019)
Phagocytosis of live and dead Escherichia coli and Staphylococcus aureus in human whole blood is markedly reduced by combined inhibition of C5aR1 and CD14.
Molecular Immunology
Academic article
-
Thomas, Anub Mathew;
Gerogianni, Alexandra;
McAdam, Martin Berner;
Fløisand, Yngvar;
Lau, Corinna;
Espevik, Terje;
Nilsson, Per;
Mollnes, Tom Eirik;
Barratt-Due, Andreas.
(2019)
Complement component C5 and TLR molecule CD14 mediate heme-induced thromboinflammation in human blood.
Journal of Immunology
Academic article
-
Pilely, Katrine;
Bakke, Siril Skaret;
Palarasah, Yaseelan;
Skjoedt, Mikkel-Ole;
Bartels, Emil D.;
Espevik, Terje;
Garred, Peter.
(2019)
Alpha-cyclodextrin inhibits cholesterol crystal-induced complement-mediated inflammation: A potential new compound for treatment of atherosclerosis.
Atherosclerosis
Academic article
-
Bösl, Korbinian;
Kandasamy, Richard Kumaran;
Espevik, Terje.
(2019)
Novel insights on human-virus interactions through genome-wide approaches.
Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
-
Lau, Corinna;
McAdam, Martin Berner;
Bergseth, Grete;
Grevys, Algirdas;
Bruun, Jack-Ansgar;
Ludviksen, Judith K;
Fure, Hilde;
Espevik, Terje;
Moen, Anders;
Andersen, Jan Terje.
(2019)
NHDL, a recombinant VL/VH hybrid antibody control for IgG2/4 antibodies.
mAbs
Academic article
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Gravastrand, Caroline S.;
Steinkjer, Bjørg;
Halvorsen, Bente;
Landsem, Anne;
Skjelland, Mona;
Jacobsen, Eva Astrid;
Woodruff, Trent M.;
Lambris, John D.;
Mollnes, Tom Eirik;
Brekke, Ole-Lars.
(2019)
Cholesterol Crystals Induce coagulation Activation through Complement-Dependent Expression of Monocytic Tissue Factor.
Journal of Immunology
Academic article
2018
-
Nejati Moharrami, Neda;
Boyartchuk, Victor;
Espevik, Terje.
(2018)
Role of CD5L in control of human innate immune function.
Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
-
Thomas, Anub Mathew;
Schjalm, Camilla;
Nilsson, Per;
Lindenskov, Paal Helge H.;
Rørtveit, Runa;
Solberg, Rønnaug;
Saugstad, Ola Didrik;
Berglund, Magnus M.;
Strömberg, Patrik;
Lau, Corinna.
(2018)
Combined Inhibition of C5 and CD14 Attenuates Systemic Inflammation in a Piglet Model of Meconium Aspiration Syndrome.
Neonatology
Academic article
-
Yurchenko, Mariya;
Skjesol, Astrid;
Ryan, Liv;
Richard, Gabriel Mary;
Kandasamy, Richard Kumaran;
Wang, Ninghai;
Terhorst, Cox;
Husebye, Harald;
Espevik, Terje.
(2018)
SLA MF1 is required for TLR4-mediated TRAM-TRIF- dependent signaling in human macrophages.
Journal of Cell Biology
Academic article
-
Kleveland, Ola;
Ueland, Thor;
Kunszt, Gabor;
Bratlie, Marte;
Yndestad, Arne;
Broch, Kaspar;
Holte, Espen;
Ryan, Liv;
Amundsen, Brage H.;
Bendz, Bjørn.
(2018)
Interleukin-6 receptor inhibition with tocilizumab induces a selective and substantial increase in plasma IP-10 and MIP-1β in non-ST-elevation myocardial infarction.
International Journal of Cardiology
Academic article
-
Skjeflo, Espen Waage;
Christiansen, Dorte;
Fure, Hilde;
Ludviksen, Judith K;
Woodruff, Trent M.;
Espevik, Terje;
Nielsen, Erik Waage;
Brekke, Ole-Lars;
Mollnes, Tom Eirik.
(2018)
Staphylococcus aureus-induced complement activation promotes tissue factor-mediated coagulation.
Journal of Thrombosis and Haemostasis
Academic article
-
Bösl, Korbinian;
Giambelluca, Miriam;
Haug, Markus;
Bugge, Marit;
Espevik, Terje;
Kandasamy, Richard Kumaran;
Bergstrøm, Bjarte Aune.
(2018)
Coactivation of TLR2 and TLR8 in primary human monocytes triggers a distinct inflammatory signaling response.
Frontiers in Physiology
Academic article
-
Orrem, Hilde Lang;
Nilsson, Per;
Pischke, Søren Erik;
Kleveland, Ola;
Yndestad, Arne;
Ekholt, Karin;
Damås, Jan Kristian;
Espevik, Terje;
Bendz, Bjørn;
Halvorsen, Bente.
(2018)
IL-6 receptor inhibition by tocilizumab attenuated expression of C5a receptor 1 and 2 in non-ST-elevation myocardial infarction.
Frontiers in Immunology
Academic article
-
Nejati Moharrami, Neda;
Tande, Erlend Bjørkøy;
Ryan, Liv;
Espevik, Terje;
Boyartchuk, Victor.
(2018)
RORα controls inflammatory state of human macrophages.
PLOS ONE
Academic article
-
Christ, Anette;
Günther, Patrick;
Lauterbach, Mario A.R.;
Duewell, Peter;
Biswas, Debjani;
Pelka, Karin;
Scholz, Claus J.;
Oosting, Marije;
Haendler, Kristian;
Baßler, Kevin.
(2018)
Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming.
Cell
Academic article
-
Landsem, Anne;
Fure, Hilde;
Ludviksen, Judith K;
Christiansen, Dorte;
Lau, Corinna;
Mathisen, Monica Dammen;
Bergseth, Grete;
Nymo, Stig Haugset;
Lappegård, Knut Tore;
Woodruff, T. M..
(2018)
Complement component 5 does not interfere with physiological hemostasis but is essential for Escherichia coli-induced coagulation accompanied by Toll-like receptor 4.
Clinical and Experimental Immunology
Academic article
2017
-
Bugge, Marit;
Bergstrøm, Bjarte;
Eide, Oda K.;
Solli, Helene;
Kjønstad, Ingrid Fadum;
Stenvik, Jørgen;
Espevik, Terje;
Nilsen, Nadra J..
(2017)
Surface Toll-Like Receptor 3 Expression in Metastatic Intestinal Epithelial Cells induces Selective Cytokine Production and Promotes Invasiveness.
Journal of Biological Chemistry
Academic article
-
Barratt-Due, Andreas;
Pischke, Søren Erik;
Nilsson, Per;
Espevik, Terje;
Mollnes, Tom Eirik.
(2017)
Dual inhibition of complement and Toll-like receptors as a novel approach to treat inflammatory diseases-C3 or C5 emerge together with CD14 as promising targets.
Journal of Leukocyte Biology
Academic literature review
-
Niyonzima, Nathalie;
Halvorsen, Bente;
Sporsheim, Bjørnar;
Garred, Peter;
Aukrust, Pål;
Mollnes, Tom Eirik;
Espevik, Terje.
(2017)
Complement activation by cholesterol crystals triggers a subsequent cytokine response.
Molecular Immunology
Academic article
-
Espada Serrano, Sandra;
Stavik, Benedicte;
Holm, Sverre;
Sagen, Ellen Lund;
Bjerkeli, Vigdis;
Skjelland, Mona;
Dahl, Tuva Børresdatter;
Espevik, Terje;
Kanse, Sandip;
Sandset, Per Morten.
(2017)
Tissue factor pathway inhibitor attenuates ER stress-induced inflammation in human M2-polarized macrophages.
Biochemical and Biophysical Research Communications - BBRC
Academic article
-
Gravastrand, Caroline;
Hamad, Shamal;
Fure, Hilde;
Steinkjer, Bjørg;
Ryan, Liv;
Oberholzer, José;
Lambris, John D.;
Lacík, Igor;
Mollnes, Tom Eirik;
Espevik, Terje.
(2017)
Alginate microbeads are coagulation compatible, while alginate
microcapsules activate coagulation secondary to complement or
directly through FXII.
Acta Biomaterialia
Academic article
-
Hellerud, Bernt C;
Orrem, Hilde Lang;
Dybwik, Knut Gustav;
Pischke, Søren Erik;
Barratt-Due, Andreas;
Castellheim, Albert;
Fure, Hilde;
Bergseth, Grete;
Christiansen, Dorte;
Nunn, Miles A..
(2017)
Combined inhibition of C5 and CD14 efficiently attenuated the inflammatory response in a porcine model of meningococcal sepsis.
Journal of Intensive Care
Academic article
-
Bakke, Siril Skaret;
Aune, Marie Hjelmseth;
Niyonzima, Nathalie;
Pilely, Katrine;
Ryan, Liv;
Skjelland, Mona;
Garred, Peter;
Aukrust, Pål;
Halvorsen, Bente;
Latz, Eicke.
(2017)
Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation.
Journal of Immunology
Academic article
-
Espevik, Terje.
(2017)
Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation.
Journal of Immunology
Academic article
-
Stavik, Benedicte;
Holm, Sverre;
Espada Serrano, Sandra;
Iversen, Nina;
Sporsheim, Bjørnar;
Bjerkeli, Vigdis;
Dahl, Tuva Børresdatter;
Sandset, Per Morten;
Skjelland, Mona;
Espevik, Terje.
(2017)
Increased expression of TFPI in human carotid stenosis.
Thrombosis Research
Academic article
-
Gregersen, Ida;
Sandanger, Øystein;
Askevold, Erik Tandberg;
Sagen, Ellen Lund;
Yang, Kuan;
Holm, Sverre;
Pedersen, Turid Margrethe;
Skjelland, Mona;
Krohg-Sørensen, Kirsten;
Hansen, Trond Vidar.
(2017)
Interleukin 27 is increased in carotid atherosclerosis and promotes NLRP3 inflammasome activation.
PLOS ONE
Academic article
-
Stavik, Benedicte;
Espada, Sandra;
Holm, Sverre;
Bjerkeli, Vigdis;
Sandset, Per Morten;
Dahl, Tuva Børresdatter;
Skjelland, Mona;
Espevik, Terje;
Iversen, Nina;
Skretting, Grethe.
(2017)
TFPI in human atherosclerotic plaques.
Research and Practice in Thrombosis and Haemostasis (RPTH)
Conference abstract
-
Ehrnstrøm, Birgitta;
Beckwith, Kai Sandvold;
Yurchenko, Mariya;
Moen, Siv Helen;
Kojen, June Frengen;
Lentini, Germana;
Teti, Guiseppe;
Damås, Jan Kristian;
Espevik, Terje;
Stenvik, Jørgen.
(2017)
Toll-Like Receptor 8 Is a Major Sensor of Group B Streptococcus But Not Escherichia coli in Human Primary Monocytes and Macrophages.
Frontiers in Immunology
Academic article
2016
-
Malmo, Jostein;
Moe, Nina;
Krokstad, Sidsel;
Ryan, Liv;
Loevenich, Simon;
Johnsen, Ingvild Bjellmo;
Espevik, Terje;
Nordbø, Svein Arne;
Døllner, Henrik;
Anthonsen, Marit Walbye.
(2016)
Cytokine profiles in human metapneumovirus infected children: Identification of genes involved in the antiviral response and pathogenesis.
PLOS ONE
Academic article
-
Nymo, Stig Haugset;
Gustavsen, Alice;
Nilsson, Per;
Lau, Corinna;
Espevik, Terje;
Mollnes, Tom Eirik.
(2016)
Human endothelial cell activation by Escherichia coli and staphylococcus aureus is mediated by TNF and IL-1β secondarily to activation of C5 and CD14 in whole blood.
Journal of Immunology
Academic article
-
Varghese, Paramel G;
Folkersen, Lasse;
Strawbridge, Rona J.;
Halvorsen, Bente;
Yndestad, Arne;
Ranheim, Trine;
Krogh-Sørensen, Kristin;
Skjelland, Mona;
Espevik, Terje;
Aukrust, Pål.
(2016)
NLRP3 inflammasome expression and activation in human atherosclerosis.
Journal of the American Heart Association (JAHA)
Academic article
-
Sherstova, Tatyana;
Stokke, Bjørn Torger;
Anthonsen, Marit Walbye;
Espevik, Terje.
(2016)
Quantitative atomic force microscopy and light microscopy of hydrogels and cells.
Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
-
Pilely, Katrine;
Rosbjerg, Anne;
Genster, Ninette;
Gál, Peter;
Pál, Gábor;
Halvorsen, Bente;
Holm, Sverre;
Aukrust, Pål;
Bakke, Siril Skaret;
Sporsheim, Bjørnar.
(2016)
Cholesterol crystals activate the lectin complement pathway via ficolin-2 and mannose-binding lectin: Implications for the progression of atherosclerosis.
Journal of Immunology
Academic article
-
Lunde, Ngoc Nguyen Dieu;
Holm, Sverre;
Dahl, Tuva Børresdatter;
Inass, Elyouncha;
Sporsheim, Bjørnar;
Gregersen, Ida;
Abbas, Azhar;
Skjelland, Mona;
Espevik, Terje;
Solberg, Rigmor.
(2016)
Increased levels of legumain in plasma and plaques from patients with carotid atherosclerosis.
Atherosclerosis
Academic article
-
Kleveland, Ola;
Kunszt, Gabor;
Bratlie, Marte;
Ueland, Thor;
Broch, Kaspar;
Holte, Espen;
Michelsen, Annika;
Bendz, Bjørn;
Amundsen, Brage H.;
Espevik, Terje.
(2016)
Effect of a single dose of the interleukin-6 receptor antagonist tocilizumab on inflammation and troponin T release in patients with non-ST-elevation myocardial infarction: a double-blind, randomized, placebo-controlled phase 2 trial.
European Heart Journal
Academic article
-
Bugge, Marit;
Nilsen, Nadra J.;
Espevik, Terje.
(2016)
Toll-Like Receptor 3 Signaling in Intestinal Epithelial Cells.
Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
-
Zimmer, Sebastian;
Grebe, Alena;
Bakke, Siril Skaret;
Bode, Niklas;
Halvorsen, Bente;
Ulas, Thomas;
Skjelland, Mona;
Nardo, Dominic De;
Labzin, Larisa I.;
Kerksiek, Anja.
(2016)
Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming.
Science Translational Medicine
Academic article
-
Niyonzima, Nathalie;
Freeley, Simon;
Arbore, Giuseppina;
Friec, Gaelle Le;
Lappegård, Knut Tore;
Mollnes, Tom Eirik;
Kemper, Claudia;
Espevik, Terje.
(2016)
The intracellular C5 system is critical to DAMP sensing and cellular responses in human monocytes.
Immunobiology
Conference abstract
-
Gustavsen, Alice;
Nymo, Stig Haugset;
Landsem, Anne;
Christiansen, Dorte;
Ryan, Liv;
Husebye, Harald;
Lau, Corinna;
Pischke, Søren Erik;
Lambris, John D.;
Espevik, Terje.
(2016)
Combined inhibition of complement and CD14 attenuates bacteria-induced inflammation in human whole blood more efficiently than antagonizing the toll-like receptor 4-MD2 complex.
Journal of Infectious Diseases
Academic article
-
Ørning, Mathias Pontus;
Hoem, Kine Samset;
Coron, Abba Elizabeth;
Skjåk-Bræk, Gudmund;
Mollnes, Tom Eirik;
Brekke, Ole Lars;
Espevik, Terje;
Rokstad, Anne Mari.
(2016)
Alginate microsphere compositions dictate different mechanisms of complement activation with consequences for cytokine release and leukocyte activation.
Journal of Controlled Release
Academic article
2015
-
Egge, Kjetil Hagene;
Barratt-Due, Andreas;
Nymo, Stig Haugset;
Lindstad, Julie Katrine;
Pharo, Anne Margrethe;
Lau, Corinna;
Espevik, Terje;
Thorgersen, Ebbe Billmann;
Mollnes, Tom Eirik.
(2015)
The anti-inflammatory effect of combined complement and CD14 inhibition is preserved during escalating bacterial load.
Clinical and Experimental Immunology
Academic article
-
Lau, Corinna;
Nygård, Ståle;
Fure, Hilde;
Olstad, Ole Kristoffer;
Holden, Marit;
Lappegård, Knut Tore;
Brekke, Ole Lars;
Espevik, Terje;
Hovig, Johannes Eivind;
Mollnes, Tom Eirik.
(2015)
CD14 and complement crosstalk and largely mediate the transcriptional response to Escherichia coli in human whole blood as revealed by DNA microarray.
PLOS ONE
Academic article
-
Klein, Dionne;
Skjesol, Astrid;
Kers-Rebel, Esther D.;
Sherstova, Tatyana;
Sporsheim, Bjørnar;
Egeberg, Kjartan Wøllo;
Stokke, Bjørn Torger;
Espevik, Terje;
Husebye, Harald.
(2015)
CD14, TLR4 and TRAM Show Different Trafficking Dynamics During LPS Stimulation.
Traffic: The moving front of cell biology
Academic article
-
Niyonzima, Nathalie;
Samstad, Eivind;
Aune, Marie Hjelmseth;
Ryan, Liv;
Bakke, Siril Skaret;
Rokstad, Anne Mari;
Wright, Samuel;
Damås, Jan Kristian;
Mollnes, Tom Eirik;
Latz, Eicke.
(2015)
Reconstituted high-density lipoprotein attenuates cholesterol crystal-induced inflammatory responses by reducing complement activation.
Journal of Immunology
Academic article
-
Lau, Corinna;
Olstad, Ole Kristoffer;
Holden, Marit;
Nygård, Ståle;
Fure, Hilde;
Lappegård, Knut Tore;
Brekke, Ole Lars;
Espevik, Terje;
Hovig, Johannes Eivind;
Mollnes, Tom Eirik.
(2015)
Gene expression profiling of Gram-negative bacteria-induced inflammation in human whole blood: The role of complement and CD14-mediated innate immune response.
Genomics Data
Academic article
-
Hovland, Anders;
Jonasson, Lena;
Garred, Peter;
Yndestad, Arne;
Aukrust, Pål;
Lappegård, Knut Tore;
Espevik, Terje;
Mollnes, Tom Eirik.
(2015)
The complement system and toll-like receptors as integrated players in the pathophysiology of atherosclerosis.
Atherosclerosis
Academic literature review
-
Sponaas, Anne-Marit;
Moen, Siv Helen;
Liabakk, Nina-Beate;
Feyzi, Emadoldin;
Holien, Toril;
Kvam, Solveig;
Grøseth, Lill Anny Gunnes;
Størdal, Berit Fladvad;
Buene, Glenn;
Espevik, Terje.
(2015)
The proportion of CD16+CD14dim monocytes increases with tumor cell load in bone marrow of patients with multiple myeloma.
Immunity,Inflammation and Disease
Academic article
-
Bergstrøm, Bjarte;
Aune, Marie Hjelmseth;
Awuh, Jane Atesoh;
Kojen, June Frengen;
Blix, Kjetil Jordahl;
Ryan, Liv;
Flo, Trude Helen;
Mollnes, Tom Eirik;
Espevik, Terje;
Stenvik, Jørgen.
(2015)
TLR8 senses Staphylococcus aureus RNA in human primary monocytes and macrophages and induces IFN-β production via a TAK1-IKKβ-IRF5 signaling pathway.
Journal of Immunology
Academic article
-
Espevik, Terje.
(2015)
Reconstituted High-Density Lipoprotein Attenuates Cholesterol Crystal-Induced Inflammatory Responses by Reducing Complement Activation.
Journal of Immunology
Academic article
-
Nilsen, Nadra;
I., Vladimer Gregory;
Stenvik, Jørgen;
Ørning, Mathias Pontus;
Zeid-Kilani, Maria Vanessa;
Bugge, Marit;
Bergstrøm, Bjarte;
Conlon, Joseph;
Husebye, Harald;
Amy, Hise.
(2015)
A role for the adaptor proteins TRAM and TRIF in toll-like receptor 2 signaling.
Journal of Biological Chemistry
Academic article
-
Skjeflo, Espen Waage;
Sagatun, Caroline;
Dybwik, Knut;
Aam, Sturla;
Urving, Sven Haakon;
Nunn, Miles A.;
Fure, Hilde;
Lau, Corinna;
Brekke, Ole Lars;
Huber-Lang, Markus.
(2015)
Combined inhibition of complement and CD14 improved outcome in porcine polymicrobial sepsis.
Critical Care
Academic article
2014
-
Franklin, Bernardo S;
Bossaller, Lukas;
Nardo, Dominic De;
Ratter, Jacqueline M;
Stutz, Andrea;
Engels, Gudrun;
Brenker, Christoph;
Nordhoff, Mark;
Mirandola, Sandra R;
Al-Amoudi, Ashraf.
(2014)
The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation.
Nature Immunology
Academic article
-
Lappegård, Knut Tore;
Garred, Peter;
Jonasson, Lena;
Espevik, Terje;
Aukrust, Pål;
Yndestad, Arne;
Mollnes, Tom Eirik;
Hovland, Anders.
(2014)
A vital role for complement in heart disease.
Molecular Immunology
Academic literature review
-
Huber-Lang, Markus;
Barratt-Due, Andreas;
Pischke, Søren Erik;
Sandanger, Øystein;
Nilsson, Per;
Nunn, Miles A.;
Denk, Stephanie;
Gaus, Wilhelm;
Espevik, Terje;
Mollnes, Tom Eirik.
(2014)
Double blockade of CD14 and complement C5 abolishes the cytokine storm and improves morbidity and survival in polymicrobial sepsis in mice.
Journal of Immunology
Academic article
-
Samstad, Eivind;
Niyonzima, Nathalie;
Nymo, Stig Haugset;
Aune, Marie Hjelmseth;
Ryan, Liv;
Bakke, Siril Skaret;
Lappegård, Knut Tore;
Brekke, Ole Lars;
Lambris, John D.;
Damås, Jan Kristian.
(2014)
Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release.
Journal of Immunology
Academic article
-
Skjeflo, Espen Waage;
Christiansen, Dorte;
Espevik, Terje;
Nielsen, Erik Waage;
Mollnes, Tom Eirik.
(2014)
Combined inhibition of complement and CD14 efficiently attenuated the inflammatory response induced by staphylococcus aureus in a human whole blood model.
Journal of Immunology
Academic article
-
Østvik, Ann Elisabet;
Granlund, Atle Van Beelen;
Gustafsson, Björn;
Torp, Sverre Helge;
Espevik, Terje;
Mollnes, Tom Eirik;
Damås, Jan Kristian;
Sandvik, Arne Kristian.
(2014)
Mucosal toll-like receptor 3-dependent synthesis of complement factor B and systemic complement activation in inflammatory bowel disease.
Inflammatory Bowel Diseases
Academic article
-
Nordgård, Catherine Taylor;
Nonstad, Unni;
Olderøy, Magnus Østgård;
Espevik, Terje;
Draget, Kurt Ingar.
(2014)
Alterations in mucus barrier function and matrix structure induced by guluronate oligomers.
Biomacromolecules
Academic article
-
Nymo, Stig Haugset;
Niyonzima, Nathalie;
Espevik, Terje;
Mollnes, Tom Eirik.
(2014)
Cholesterol crystal-induced endothelial cell activation is complement-dependent and mediated by TNF.
Immunobiology
Academic article
-
Arlov, Øystein;
Aachmann, Finn Lillelund;
Sundan, Anders;
Espevik, Terje;
Skjåk-Bræk, Gudmund.
(2014)
Heparin-Like Properties of Sulfated Alginates with Defined Sequences and Sulfation Degrees.
Biomacromolecules
Academic article
2013
-
Nymo, Stig Haugset;
Samstad, Eivind;
Niyonzima, Nathalie;
Aune, Marie Hjelmseth;
Bergseth, Grete;
Ryan, Liv;
Brekke, Ole Lars;
Latz, E;
Lambris, J.D.;
Espevik, Terje.
(2013)
Cholesterol crystals activate the complement system and are phagocytosed in a complement-dependent manner.
Molecular Immunology
Conference abstract
-
Samstad, Eivind;
Niyonzima, Nathalie;
Nymo, Stig Haugset;
Aune, Marie Hjelmseth;
Ryan, Liv;
Brekke, Ole Lars;
Sandanger, I;
Aukrust, Pål;
Damås, Jan Kristian;
Latz, Eicke.
(2013)
Cholesterol crystals induce inflammasome activation and cytolcine release in a complement-dependent manner.
Molecular Immunology
Conference abstract
-
Hetland, Geir;
Tryggestad, Anne Merete Aaland;
Espevik, Terje;
Ryan, Liv.
(2013)
The medicinal mushroom Agaricus blazei Murill promotes NF-B activation via stimulation of TLR2 and inhibits its activation via TLR4.
Journal of Pharmaceutical and Biomedical Sciences
Academic article
-
Østvik, Ann Elisabet;
Granlund, Atle;
Bugge, Marit;
Nilsen, Nadra;
Torp, Sverre Helge;
Waldum, Helge;
Damås, Jan Kristian;
Espevik, Terje;
Sandvik, Arne Kristian.
(2013)
Enhanced expression of CXCL10 in inflammatory bowel disease: Potential role of mucosal toll-like 3 receptor stimulation.
Inflammatory Bowel Diseases
Academic article
-
Mollnes, Tom Eirik;
Barratt-Due, Andreas;
Pischke, Søren Erik;
Sandanger, Inger;
Nilsson, Per;
Lambris, J;
Nunn, Miles A.;
Denk, Stephanie;
Espevik, Terje;
Huber-Lang, Markus.
(2013)
Double-blockade of CD14 and complement component C5 abolish the inflammatory storm and improve survival in mouse polymicrobial sepsis.
Molecular Immunology
Conference abstract
-
Espevik, Terje.
(2013)
Sensorer som setter i gang betennelse: hvordan virker de og hvorfor trenger vi dem?.
Årbok / Det norske videnskaps-akademi
Popular science article
-
Grimstad, Øystein;
Husebye, Harald;
Espevik, Terje.
(2013)
TLR3 mediates release of IL-1 beta and cell death in keratinocytes in a caspase-4 dependent manner.
Journal of dermatological science (Amsterdam)
Academic article
-
Granlund, Atle Van Beelen;
Flatberg, Arnar;
Østvik, Ann Elisabet;
Drozdov, Ignat;
Gustafsson, Björn;
Kidd, Mark;
Beisvag, Vidar;
Torp, Sverre Helge;
Waldum, Helge;
Martinsen, Tom Christian.
(2013)
Whole Genome Gene Expression Meta-Analysis of Inflammatory Bowel Disease Colon Mucosa Demonstrates Lack of Major Differences between Crohn's Disease and Ulcerative Colitis.
PLOS ONE
Academic article
-
Sandanger, Øystein;
Ranheim, Trine;
Vinge, Leif Erik;
Bliksøen, Marte;
Alfsnes, Katrine;
Finsen, Alexandra;
Dahl, Christen Peder;
Askevold, Erik Tandberg;
Florholmen, Geir;
Christensen, Geir Arve.
(2013)
The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury.
Cardiovascular Research (CVR)
Academic article
-
Rokstad, Anne Mari;
Brekke, Ole Lars;
Steinkjer, Bjørg;
Ryan, Liv;
Kolláriková, Gabriela;
Strand, Berit Løkensgard;
Skjåk-Bræk, Gudmund;
Lambris, John D.;
Lacík, Igor;
Mollnes, Tom Eirik.
(2013)
The induction of cytokines by polycation containing microspheres by a complement dependent mechanism.
Biomaterials
Academic article
-
Lau, Corinna;
Gunnarsen, Kristin Støen;
Høydahl, Lene Støkken;
Andersen, Jan Terje;
Berntzen, Gøril;
Pharo, Anne Margrethe;
Lindstad, Julie Katrine;
Ludviksen, Judith K;
Brekke, Ole Lars;
Barratt-Due, Andreas.
(2013)
Chimeric Anti-CD14 IGG2/4 Hybrid Antibodies for Therapeutic Intervention in Pig and Human Models of Inflammation.
Journal of Immunology
Academic article
-
Østvik, Ann Elisabet;
Granlund, Atle Van Beelen;
Torp, Sverre Helge;
Flatberg, Arnar;
Beisvag, Vidar;
Waldum, Helge;
Flo, Trude Helen;
Espevik, Terje;
Damås, Jan Kristian;
Sandvik, Arne Kristian.
(2013)
Expression of Toll-like receptor-3 is enhanced in active inflammatory bowel disease and mediates the excessive release of lipocalin 2.
Clinical and Experimental Immunology
Academic article
-
Rokstad, Anne Mari;
Strand, Berit Løkensgard;
Espevik, Terje;
Mollnes, Tom Eirik.
(2013)
Biocompatibility and Biotolerability Assessment of Microspheres Using a Whole Blood Model.
Micro and Nanosystems
Academic article
2012
-
Rokstad, Anne Mari;
Brekke, Ole Lars;
Steinkjer, Bjørg;
Ryan, Liv;
Kolláriková, Gabriela;
Lambris, John D.;
Lacík, Igor;
Mollnes, Tom Eirik;
Espevik, Terje.
(2012)
Poly-cation containing alginate microcapsules induce cytokines by a complement-dependent mechanism.
Immunobiology
Conference abstract
-
Christiansen, Dorte;
Stenvik, Jørgen;
Brekke, Ole Lars;
Lambris, John D.;
Espevik, Terje;
Mollnes, Tom Eirik.
(2012)
Phagocytosis of Escherichia coli in human whole blood: Early complement dependency is succeeded by late CD14 dependency over time.
Immunobiology
Conference abstract
-
Østvik, Ann Elisabet;
Granlund, Atle Van Beelen;
Torp, Sverre Helge;
Flatberg, Arnar;
Waldum, Helge;
Espevik, Terje;
Damås, Jan Kristian;
Sandvik, Arne Kristian.
(2012)
Induction of Lipocalin-2 in Colonic Epithelial Cells in Inflammatory Bowel Disease.
Inflammatory Bowel Diseases
Conference abstract
-
Østvik, Ann Elisabet;
Nilsen, Nadra;
Granlund, Atle;
Torp, Sverre Helge;
Flatberg, Arnar;
Waldum, Helge;
Espevik, Terje;
Damås, Jan Kristian;
Sandvik, Arne Kristian.
(2012)
Enhanced expression of CXCL10 in inflammatory bowel disease-role of mucosal TLR3 stimulation.
Journal of Crohn’s and Coltis Supplements
Conference abstract
-
Nymo, Stig;
Samstad, Eivind;
Niyonzima, Nathalie;
Bergseth, Grethe;
Christiansen, Dorte;
Ryan, Liv;
Brekke, Ole Lars;
Lappegard, Knut Tore;
Damas, Jan Kristian;
Latz, Eicke.
(2012)
Complement dependency of cholesterol crystal-induced inflammation - I. Pathway activation mechanisms, cytokine responses and endothelial cell activation.
Immunobiology
Conference abstract
-
Skjeflo, Espen;
Christiansen, Dorte;
Lambris, John D.;
Espevik, Terje;
Nielsen, Erik Waage;
Mollnes, Tom Eirik.
(2012)
Combined inhibition of complement and CD14 efficiently attenuated the inflammatory response induced by Staphylococcus aureus in a human whole blood model.
Immunobiology
Conference abstract
-
Rokstad, Anne Mari;
Gustafsson, Björn;
Espevik, Terje;
Bakke, Ingunn;
Pfragner, Roswitha;
Svejda, Bernhard;
Modlin, Irvin M;
Kidd, Mark.
(2012)
Microencapsulation of small intestinal neuroendocrine neoplasm cells for tumor model studies.
Cancer Science
Academic article
-
Niyonzima, Nathalie;
Samstad, Eivind;
Aune, Marie Hjelmseth;
Ryan, Liv;
Damås, Jan Kristian;
Wright, Samuel;
Sandanger, Øystein;
Aukrust, Pål;
Latz, Eicke;
Mollnes, Tom Eirik.
(2012)
Complement dependency of cholesterol crystal-induced inflammation - II. Inflammasome activation and regulation mechanisms involving reconstituted high density lipoprotein (HDL) and C-reactive protein (CRP).
Immunobiology
Conference abstract
-
Stenvik, Jørgen;
Sletta, Håvard;
Grimstad, Øystein;
Pukstad, Brita;
Ryan, Liv;
Aune, Randi;
Strand, Wenche Iren;
Tøndervik, Anne;
Torp, Sverre Helge;
Skjåk-Bræk, Gudmund.
(2012)
Alginates induce differentiation and expression of CXCR7 and CXCL12/SDF-1 in human keratinocytes - the role of calcium.
Journal of Biomedical Materials Research. Part A
Academic article
-
Barratt-Due, Andreas;
Pischke, Søren Erik;
Brekke, Ole Lars;
Thorgersen, Ebbe Billmann;
Nielsen, Erik Waage;
Espevik, Terje;
Huber-Lang, Markus;
Mollnes, Tom Eirik.
(2012)
Bride and groom in systemic inflammation - The bells ring for complement and Toll in cooperation.
Immunobiology
Academic literature review
-
Granlund, Atle;
Flatberg, Arnar;
Østvik, Ann Elisabet;
Drozdov, I;
Gustafsson, Björn;
Kidd, M;
Beisvag, Vidar;
Torp, Sverre Helge;
Waldum, Helge;
Martinsen, Tom Christian.
(2012)
Dissecting the IBD Transcriptome.
Inflammatory Bowel Diseases
Conference abstract
-
Doyle, SL;
Husebye, Harald;
Connolly, D;
Espevik, Terje;
O'Neill, LAJ;
McGettrick, AF.
(2012)
The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation.
Nature Communications
Academic article
-
Mollnes, Tom Eirik;
Barratt-Due, Andreas;
Pischke, Søren Erik;
Sandanger, Øystein;
Nunn, Miles A.;
Espevik, Terje;
Denk, Stephanie;
Huber-Lang, Markus.
(2012)
The systemic inflammatory reaction in polymicrobial sepsis induced by murine cecal ligation and puncture is equally dependent on C5 and CD14.
Immunobiology
Conference abstract
-
Grimstad, Øystein;
Pukstad, Brita;
Stenvik, Jørgen;
Espevik, Terje.
(2012)
Oligodeoxynucleotides inhibit Toll-like receptor 3 mediated cytotoxicity and CXCL8 release in keratinocytes.
Experimental Dermatology
Academic article
-
Lau, Corinna;
Gunnarsen, Kristin Støen;
Høydahl, Lene Støkken;
Berntzen, Gøril;
Stokes, Christopher R.;
Espevik, Terje;
Sandlie, Inger;
Mollnes, Tom Eirik.
(2012)
Recombinant anti-human and anti-porcine CD14 antibodies.
Immunobiology
Conference abstract
-
Klein, Dionne;
Øvrebø, Kirsti Marie;
Latz, Eicke;
Espevik, Terje;
Stokke, Bjørn Torger.
(2012)
Direct measurement of the interaction force between immunostimulatory CpG-DNA and TLR9 fusion protein.
Journal of Molecular Recognition
Academic article
-
Christiansen, Dorte;
Brekke, Ole Lars;
Stenvik, Jørgen;
Lambris, J.D.;
Espevik, Terje;
Mollnes, Tom Eirik.
(2012)
Differential Effect of Inhibiting MD-2 and CD14 on LPS- Versus Whole E. coli Bacteria-Induced Cytokine Responses in Human Blood.
Advances in Experimental Medicine and Biology
Academic article
2011
-
Rokstad, Anne Mari;
Brekke, Ole Lars;
Steinkjer, Bjørg;
Ryan, Liv;
Kolláriková, Gabriela;
Strand, Berit Løkensgard;
Skjåk-Bræk, Gudmund;
Lacík, Igor;
Espevik, Terje;
Mollnes, Tom Eirik.
(2011)
Alginate microbeads are complement compatible, in contrast to polycation containing microcapsules, as revealed in a human whole blood model.
Acta Biomaterialia
Academic article
-
Torgersen, Maria Lyngaas;
Engedal, Kim Nikolai;
Pedersen, Anne-Mari Gjestvang;
Husebye, Harald;
Espevik, Terje;
Sandvig, Kirsten.
(2011)
Toll-like receptor 4 facilitates binding of Shiga toxin to colon carcinoma and primary umbilical vein endothelial cells.
FEMS Immunology and Medical Microbiology
Academic article
-
Nørgaard, Nikolai Nordberg;
Holien, Toril;
Jönsson, S;
Hella, Hanne;
Espevik, Terje;
Sundan, Anders;
Standal, Therese.
(2011)
CpG-ODN inhibits Smad-dependent BMP signaling; Effects on myeloma cell apoptosis and in vitro osteoblastogenesis.
Bone
Conference abstract
-
Grimstad, Øystein;
Sandanger, Øystein;
Ryan, Liv;
Otterdal, Kari;
Damås, Jan Kristian;
Pukstad, Brita;
Espevik, Terje.
(2011)
Cellular sources and inducers of cytokines present in acute wound fluid.
Wound Repair and Regeneration
Academic article
2010
-
Hetland, Geir;
Tryggestad, Anne Merete Aaland;
Espevik, Terje;
Ryan, Liv;
Tangen, Jon-Magnus;
Johnson, Egil;
Kvalheim, Gunnar.
(2010)
The medicinal and antitumour mushroom, agaricus blazei murill, activates NF-KB via TLR2 in monocytic cells and induces expression of cell surface markers and production of cytokines in human monocyte-derived dendritic cells (MDDC) in vitro.
European Journal of Cancer
Conference abstract
-
Halaas, Øyvind;
Steigedal, Magnus;
Haug, Markus;
Awuh, Jane Atesoh;
Ryan, Liv;
Brech, Andreas;
Sato, S;
Husebye, Harald;
Cangelosi, Gerard;
Akira, Shizuo.
(2010)
Intracellular Mycobacterium avium Intersect Transferrin in the Rab11(+) Recycling Endocytic Pathway and Avoid Lipocalin 2 Trafficking to the Lysosomal Pathway.
Journal of Infectious Diseases
Academic article
-
Klein, Dionne C.G.;
Latz, Eicke;
Espevik, Terje;
Stokke, Bjørn Torger.
(2010)
Higher order structure of short immunostimulatory oligonucleotides studied by atomic force microscopy.
Ultramicroscopy
Academic article
-
Salvesen, Bodil;
Stenvik, Jørgen;
Rosetti, Carlo;
Saugstad, Ola D;
Espevik, Terje;
Mollnes, Tom E..
(2010)
Meconium-induced release of cytokines is mediated by the TRL4/MD-2 complex in a CD14-dependent manner.
Molecular Immunology
Academic article
-
Duewell, P;
Kono, H;
Rayner, KJ;
Sirois, CM;
Vladimer, G;
Bauernfeind, FG;
Abela, GS;
Franchi, L;
Nunez, G;
Schnurr, M.
(2010)
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
Nature
Academic article
-
Etokebe, GE;
Skjeldal, F;
Nilsen, Nadra;
Rodionov, Dmitrii;
Knezevic, Jelena;
Bulat-Kardum, Ljiljana;
Espevik, Terje;
Bakke, Oddmund;
Dembic, Zlatko.
(2010)
Toll-Like Receptor 2 (P631H) Mutant Impairs Membrane Internalization and is a Dominant Negative Allele.
Scandinavian Journal of Immunology
Academic article
-
Nilsen, Asbjørn Magne;
Vik, Randi;
Behrens, Carl;
Drabløs, Per Arne;
Espevik, Terje.
(2010)
Beryllium Sensitivity Among Workers at a Norwegian Aluminum Smelter.
American Journal of Industrial Medicine
Academic article
-
Nørgaard, Nikolai Nordberg;
Holien, Toril;
Jonsson, Sofia;
Hella, Hanne;
Espevik, Terje;
Sundan, Anders;
Standal, Therese.
(2010)
CpG-Oligodeoxynucleotide Inhibits Smad-Dependent Bone Morphogenetic Protein Signaling: Effects on Myeloma Cell Apoptosis and In Vitro Osteoblastogenesis.
Journal of Immunology
Academic article
-
Grimstad, Øystein;
Pukstad, Brita;
Stenvik, Jørgen;
Espevik, Terje.
(2010)
TLR3 mediated cytotoxicity in keratinocytes is inhibited by co-stimulation with oligodeoxynucleotides.
Journal of Investigative Dermatology
Conference abstract
-
Pukstad, Brita;
Ryan, Liv;
Flo, Trude Helen;
Stenvik, Jørgen;
Moseley, Ryan;
Harding, Keith;
Thomas, David W.;
Espevik, Terje.
(2010)
Non-healing is associated with persistent stimulation of the innate immune response in chronic venous leg ulcers.
Journal of dermatological science (Amsterdam)
Academic article
-
Husebye, Harald;
Aune, Marie Hjelmseth;
Stenvik, Jørgen;
Samstad, Eivind Ottersen;
Skjeldal, Frode Miltzow;
Halaas, Øyvind;
Nilsen, Nadra;
Stenmark, Harald Alfred;
Latz, Eicke;
Lien, Egil.
(2010)
The Rab11a GTPase Controls Toll-like Receptor 4-Induced Activation of Interferon Regulatory Factor-3 on Phagosomes.
Immunity
Academic article
-
Hetland, Geir;
Tryggestad, Anne Merete Aaland;
Espevik, Terje;
Ryan, Liv;
Tangen, Jon-Magnus;
Johnson, Egil;
Kvalheim, Gunnar.
(2010)
The Medicinal and Antitumor Mushroom, Agaricus Blazei Murill, Activates NF-kappa B Via TLR2 but Not TLR4 In Monocytic Cells, and Stimulates Monocyte-Derived Dendritic Cells (MDDC) to Increased Cell Surface Marker Expression and Cytokine Production, and May Thus Have Adjuvant Effect In MDDC Cancer Vaccines.
Blood
Conference abstract
-
Christiansen, D;
Brekke, Ole Lars;
Stenvik, Jørgen;
Lambris, JD;
Espevik, Terje;
Mollnes, Tom Eirik.
(2010)
Differential effect of inhibiting MD-2 and CD14 on LPS- versus whole E. coli bacteria-induced cytokine responses in human blood.
Molecular Immunology
Conference abstract
2009
-
Castellheim, A;
Brekke, Ole Lars;
Espevik, T;
Harboe, M;
Harboe, M;
Mollnes, Tom Eirik.
(2009)
Innate Immune Responses to Danger Signals in Systemic Inflammatory Response Syndrome and Sepsis.
Scandinavian Journal of Immunology
Academic literature review
-
Iversen, Ann-Charlotte;
Steinkjer, Bjørg;
Nilsen, Nadra;
Bohnhorst, Janne Øvrebø;
Moen, Siv Helen;
Vik, Randi;
Stephens, Phil;
Thomas, DW;
Benedict, Chris A.;
Espevik, Terje.
(2009)
A proviral role for CpG in cytomegalovirus infection.
Journal of Immunology
Academic article
-
Standal, Therese;
Norgaard, NN;
Bohnhorst, J;
Espevik, T;
Waage, A;
Sundan, A.
(2009)
Does Toll-like Receptor 9 Signaling Play a Role in Myeloma Disease Progression?.
Clinical Lymphoma & Myeloma
Conference abstract
-
Palsson-McDermott, EM;
Doyle, SL;
McGettrick, AF;
Hardy, M;
Husebye, Harald;
Banahan, K;
Gong, M;
Golenbock, D;
Espevik, Terje;
O'Neill, LAJ.
(2009)
TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway.
Nature Immunology
Academic article
-
Sandanger, Øystein;
Sandanger, O;
Ryan, Liv;
Bohnhorst, Janne Øvrebø;
Iversen, Ann-Charlotte;
Iversen, AC;
Husebye, Harald;
Halaas, Øyvind;
Halaas, O;
Landrø, Linn.
(2009)
IL-10 Enhances MD-2 and CD14 Expression in Monocytes and the Proteins Are Increased and Correlated in HIV-Infected Patients.
Journal of Immunology
Academic article
-
Espevik, Terje;
Rokstad, Anne Mari;
Kulseng, Bård Eirik;
Strand, Berit Løkensgard;
Skjåk-Bræk, Gudmund.
(2009)
Mechanisms of the host immune response to alginate microcapsules.
Non-fiction chapter
-
Yndestad, A;
Landrø, Linn;
Ueland, Thor;
Dahl, CP;
Flo, Trude Helen;
Vinge, Leif Erik;
Espevik, Terje;
Frøland, Stig S;
Husberg, Cathrine;
Christensen, Geir.
(2009)
Increased systemic and myocardial expression of neutrophil gelatinase-associated lipocalin in clinical and experimental heart failure.
European Heart Journal
Academic article
-
Damås, Jan Kristian;
Davi, Giovanni;
Jensenius, M;
Santilli, F;
Otterdal, K;
Ueland, T;
Flo, Trude Helen;
Lien, E;
Espevik, Terje;
Frøland, Stig S.
(2009)
Relative chemokine and adhesion molecule expression in Mediterranean spotted fever and African tick bite fever.
Journal of Infection
Academic article
2008
-
Klein, Dionne C.G.;
Latz, Eicke;
Espevik, Terje;
Stokke, Bjørn Torger.
(2008)
Effects of CpG-DNA on Toll-like receptor 9 studied by AFM.
TRAUNER Verlag
Anthology
-
Hellerud, BC;
Stenvik, Jørgen;
Espevik, Terje;
Lambris, John D.;
Mollnes, Tom Eirik;
Brandtzaeg, P.
(2008)
Stages of meningococcal sepsis stimulated in vitro, with emphasis on complement and Toll-like receptor activation.
Infection and Immunity
Academic article
-
Hellerud, BC;
Stenvik, Jørgen;
Espevik, Terje;
Lambris, JD;
Mollnes, TE;
Brandtzæg, Petter.
(2008)
Stages of meningococcal sepsis simulated in vitro, with emphasis on complement and Toll-like receptor activation.
Infection and Immunity
Academic article
-
Nilsen, Nadra;
Deininger, S;
Nonstad, Unni;
Skjeldal, F;
Husebye, Harald;
Rodionov, D;
Aulock, S von;
Hartung, T;
Lien, E;
Lien, E.
(2008)
Cellular trafficking of lipoteichoic acid and Toll-like receptor 2 in relation to signaling; role of CD14 and CD36.
Journal of Leukocyte Biology
Academic article
-
Landrø, Linn Aina Ysland;
Landro, L;
Damås, Jan Kristian;
Damas, JK;
Flo, Trude Helen;
Heggelund, L;
Ueland, T;
Tjønnfjord, Geir Erland;
Tjonnfjord, GE;
Espevik, Terje.
(2008)
Decreased serum lipocalin-2 levels in human immunodeficiency virus-infected patients: increase during highly active anti-retroviral therapy.
Clinical and Experimental Immunology
Academic article
-
Mollnes, Tom Eirik;
Christiansen, D;
Brekke, Ole Lars;
Espevik, T.
(2008)
Hypothesis: Combined inhibition of complement and CD14 as treatment regimen to attenuate the inflammatory response.
Advances in Experimental Medicine and Biology
Academic article
-
Halaas, Øyvind;
Husebye, Harald;
Stenmark, Harald;
Espevik, Terje.
(2008)
Intracellular Trafficing of Toll-like Receptors.
Academic chapter
-
Nilsen, Nadra;
Espevik, Terje;
Lien, Egil.
(2008)
TOLL-LIKE RECEPTOR 2 EXPRESSION, REGULATION AND SIGNALING.
Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
-
Hetland, G;
Tryggestad, AMA;
Forland, T;
Johnson, E;
Ryan, L;
Espevik, Terje.
(2008)
Proposed immunomodulatory co-therapy for hematological cancer by the medicinal mushroom Agaricus blazei Murill, is facilitated by its stimulation of TLR2 and activation of NF-KB.
Vox Sanguinis
Conference abstract
2007
-
Tunheim, G;
Thompson, KM;
Fredriksen, AB;
Espevik, Terje;
Schjetne, KW;
Bogen, B.
(2007)
Human receptors of innate immunity (CD14, TLR2) are promising targets for novel recombinant immunoglobulin-based vaccine candidates.
Vaccine
Academic article
-
Halaas, Øyvind;
Husebye, Harald;
Espevik, Terje.
(2007)
The journey of Toll-like receptors in the cell.
Advances in Experimental Medicine and Biology
Academic article
-
Latz, E;
Verma, Anjali;
Visintin, A;
Gong, Mei;
Sirois, CM;
Klein, Dionne;
Monks, BG;
Mcknight, C. james;
Duprex, W. paul;
Espevik, Terje.
(2007)
Corrigendum: Ligand-induced conformational changes allosterically activate Toll-like receptor 9.
International Immunology
Academic article
-
Latz, Eicke;
Verma, Anjali;
Visintin, A;
Gong, Mei;
Sirois, Cherilyn m.;
Klein, Dionne;
Monks, Brian G.;
Mcknight, C. james;
Lamphier, Marc s.;
Duprex, W. paul.
(2007)
Ligand-induced conformational changes allosterically activate Toll-like receptor 9.
Nature Immunology
Academic article
2006
-
Bohnhorst, Janne Øvrebø;
Rasmussen, T;
Moen, Siv H;
Fløttum, Marianne;
Knudsen, L;
Børset, Magne;
Espevik, Terje;
Sundan, Anders.
(2006)
Toll-like receptors mediate proliferation and survival of multiple myeloma cells.
Leukemia
Academic article
-
Rokstad, Anne Mari Aukan;
Donati, Ivan;
Borgogna, Massimiliano;
Oberholzer, José;
Strand, Berit Løkensgard;
Espevik, Terje;
Skjåk-Bræk, Gudmund.
(2006)
Cell-compatible covalently reinforced beads obtained from a chemoenzymatically engineered alginate.
Biomaterials
Academic article
-
Espevik, Terje;
Skjåk-Bræk, Gudmund.
(2006)
Friskere fisk med tang og tare.
Gemini
Popular science article
-
Nilsen, Asbjørn Magne;
Vik, Randi;
Espevik, Terje.
(2006)
Be-LPT testing at Hydro Aluminium Karmøy AS. Final Report. June 2006.
Norwegian University of Science and Technology
Research report
-
Nilsen, Asbjørn Magne;
Vik, Randi;
Espevik, Terje.
(2006)
Be-LPT testing Karmøy. Undervegsrapport 3. Mars 2006.
Norges teknisk-naturvitenskapelige universitet
Research report
-
Nilsen, Asbjørn Magne;
Vik, Randi;
Espevik, Terje.
(2006)
Be-LPT testing Karmøy. Undervegsrapport 4. April 2006.
Norges teknisk-naturvitenskapelige universitet
Research report
-
Espevik, Terje;
Lien, Egil.
(2006)
Vaksine mot svartedauen.
Gemini
Popular science article
-
Nilsen, Asbjørn Magne;
Vik, Randi;
Espevik, Terje.
(2006)
BeLPT testing Karmøy. Undervegsrapport 1. Januar 2006.
Norges teknisk-naturvitenskapelige universitet
Research report
-
Nilsen, Asbjørn Magne;
Vik, Randi;
Espevik, Terje.
(2006)
Be-LPT testing Karmøy. Undervegsrapport 2. Februar 2006.
Norges teknisk-naturvitenskapelige universitet
Research report
-
Husebye, Harald;
Halaas, Øyvind;
Stenmark, Harald;
Tunheim, G;
Sandanger, Øystein;
Bogen, B;
Brech, A;
Latz, Eicke;
Espevik, Terje.
(2006)
Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity.
EMBO Journal
Academic article
-
Ueland, Thor;
Espevik, Terje;
Kjekshus, John;
Gullestad, Lars;
Omland, Torbjørn;
Squire, Iain B.;
Frøland, Stig S.;
Froland, Stig S;
Mollnes, Tom Eirik;
dickstein, Kenneth.
(2006)
Mannose binding lectin and soluble Toll-lilke receptor 2 in heart failure following acute myocardial infarction.
Journal of Cardiac Failure
Academic article
-
Johnsen, Ingvild Bjellmo;
Nguyen, Thank Thuy Thi;
Ringdal, Monika;
Tryggestad, AM;
Bakke, Oddmund;
Lien, Egil;
Espevik, Terje;
Anthonsen, Marit Walbye.
(2006)
Toll-like receptor 3 associates with c-Src tyrosine kinase on endosomes to initiate antiviral signaling.
EMBO Journal
Academic article
2005
-
Rokstad, Anne Mari Aukan;
Bjerkvig, Rolf;
Espevik, Terje;
Lund-Johansen, M.
(2005)
Applications of Cell Immobilisation Biotechnology, Focus on Biotechnology.
Book chapter: Cell encapsulation therapy for malignant gliomas.
Springer
Anthology
-
Heggelund, Lars;
Mollnes, Tom Eirik;
Espevik, Terje;
Muller, Fredrik;
Kristiansen, Knut Ivan;
Aukrust, Pål;
Frøland, Stig Sophus.
(2005)
Modulatory effect of mannose-binding lectin on cytokine responses: possible roles in HIV infection.
European Journal of Clinical Investigation
Academic article
-
Dybdahl, Brit;
Slørdahl, Stig Arild;
Waage, Anders;
Kierulf, Peter;
Espevik, Terje;
Sundan, Anders.
(2005)
Myocardial ischaemia and the inflammatory response: release of heat shock protein 70 after myocardial infarction.
Heart
Academic article
-
Mancuso, Guiseppe;
Midiri, A;
Biondo, Carmelo;
Beninati, C.;
Gambuzza, M;
Macri, D;
Bellantoni, A;
Weintraub, A;
Espevik, Terje;
Teti, Guiseppe.
(2005)
Bacteroides fragilis-derived lipopolysaccharide produces cell activation and lethal toxicity via toll-like receptor 4.
Infection and Immunity
Academic article
-
Manukyan, M;
Triantafilou, K;
Triantafilou, M;
Mackie, A;
Nilsen, Nadra Jesmine;
Espevik, Terje;
Wiesmullers, KH;
Ulmer, AJ;
Heine, H.
(2005)
Binding of lipopeptide to CD14 induces physical proximity of CD14, TLR2 and TLR1.
European Journal of Immunology
Academic article
-
Heggelund, L;
Mollnes, TE;
Espevik, Terje;
Muller, F;
Kristiansen, KI;
Aukrust, P;
Frøland, Stig S.
(2005)
Modulatory effect of mannose-binding lectin on cytokine responses: roles in HIV infection.
European Journal of Clinical Investigation
Academic article
-
Heggelund, L;
Mollnes, TE;
Espevik, Terje;
Muller, F;
Kristiansen, KI;
Aukrust, P;
Froland, SS.
(2005)
Modulatory effect of mannose-binding lectin on cytokine resposes: possible roles in HIV infection.
European Journal of Clinical Investigation
Academic article
2004
-
Heggelund, L;
Muller, F;
Lien, E;
Yndestad, A;
Ueland, T;
Kristiansen, KI;
Espevik, Terje;
Aukrust, P;
Frøland, Stig Sophus;
Froland, SS.
(2004)
Increased expression of Toll-like receptor 2 on monocytes in HIV infection: Possible roles in inflammation and viral replication.
Clinical Infectious Diseases
Academic article
-
Espevik, Terje.
(2004)
Tolerance induced by the lipopeptide Pam3Cys is due to ablation of IL-1R-associated kinase-1.
Journal of Immunology
Academic article
-
Dybdahl, Brit;
Wahba, Alexander;
Haaverstad, Rune;
Kirkeby-Garstad, I.;
Kierulf, P;
Espevik, Terje;
Sundan, A.
(2004)
On-pump versus off-pump coronary artery bypass grafting: more heat-shock protein 70 is released after on-pump surgery.
European Journal of Cardio-Thoracic Surgery
Academic article
-
Latz, E;
Visintin, A;
Espevik, Terje;
Golenbock, DT.
(2004)
Mechanisms of TLR9 activation.
Journal of Endotoxin Research
Academic article
-
Heggelund, L;
Damås, Jan Kristian;
Damas, JK;
Yndestad, A;
Holm, AM;
Muller, F;
Lien, E;
Lien, E;
Espevik, Terje;
Aukrust, P.
(2004)
Stimulation of toll-like receptor 2 in mononuclear cells from HIV-infected patients induces chemokine responses: possible pathogenic consequences.
Clinical and Experimental Immunology
Academic article
-
Liabakk, Nina-Beate;
Espevik, Terje.
(2004)
Monoclonal antibodies against TRAIL.
Vitamines and Hormones
Academic article
-
Latz, E;
Schoenemeyer, A;
Visintin, A;
Fitzgerald, KA;
Monks, BG;
Knetter, Cathrine;
Lien, E;
Nilsen, Nadra;
Espevik, Terje;
Golenbock, DT.
(2004)
TLR9 signals after translocating from the ER to CpG DNA in the lysosome.
Nature Immunology
Academic article
-
Heggelund, Lars;
Flo, T;
Berg, K;
Lien, T;
Mollnes, TE;
Ueland, Thor;
Aukrust, Pål;
Espevik, T;
Frøland, Stig Sophus.
(2004)
Soluble toll-like receptor 2 in HIV infection: association with disease progression.
AIDS (London)
Academic article
-
Dybdahl, Brit;
Wahba, Alexander;
Haaverstad, R;
Kirkeby-Garstad, Idar;
Kierulf, Peter;
Espevik, Terje;
Sundan, Anders.
(2004)
On-pump versus off-pump coronary artery bypass grafting: more heat-shock protein 70 is released after on-pump surgery.
European Journal of Cardio-Thoracic Surgery
Academic article
-
Frantisek, S;
Latz, E;
Re, F;
Mandell, L;
Repik, G;
Golenbock, D;
Espevik, Terje;
Kurt-Jones, E;
Finberg, R.
(2004)
Importance of extra-and intracellular domains of TLR1 and TLR2 receptors in NF-kappa B signaling.
Tissue Antigens
Conference abstract
-
Nilsen, Nadra;
Nonstad, Unni;
Kahn, Naseema;
Knetter, Cathrine;
Akira, Shizuo;
Sundan, Anders;
Espevik, Terje;
Lien, Egil.
(2004)
Lipopolysaccharide and Double-stranded RNA Up-regulate Toll-like Receptor 2 Independently of Myeloid Differentiation Factor 88.
Journal of Biological Chemistry
Academic article
-
Halaas, Øyvind;
Liabakk, Nina-Beate;
Vik, Randi;
Beninati, C;
Henneke, P;
Sundan, Anders;
Espevik, Terje.
(2004)
Monocytes stimulated with group B Streptococci or interferons release tumour necrosis factor-related apoptosis-inducing ligand.
Scandinavian Journal of Immunology
Academic article
-
Nilsen, N;
Nonstad, U;
Khan, N;
Knetter, Cathrine;
Akira, S;
Sundan, Anders;
Espevik, Terje;
Lien, E.
(2004)
Lipopolysaccharide and double-stranded RNA up-regulate toll-like receptor 2 independently of myeloid differentiation factor 88.
Journal of Biological Chemistry
Academic article
-
Heggelund, L;
Flo, Trude Helen;
Berg, K.;
Lien, E;
Espevik, Terje.
(2004)
Soluble toll-like receptor 2 in HIV infection: association with disease progression.
AIDS (London)
Academic article
2003
-
Sandor, F;
Latz, Eicke;
Mandell, L;
Repik, G;
Golenbock, Douglas T.;
Espevik, Terje;
Kurt-Jones, EA;
Finberg, RW.
(2003)
Importance of extra- and intracellular domains of TLR1 and TLR2 in NFkappa B signaling.
Journal of Cell Biology
Academic article
-
Espevik, Terje;
Latz, Eicke;
Lien, Egil;
Monks, Brian G..
(2003)
Cell distribution and functions of Toll-like receptor 4 studied by fluorescent gene constructs.
Scandinavian Journal of Infectious Diseases
Academic article
-
Visintin, A;
Latz, Eicke;
Monks, Brian G.;
Espevik, Terje;
Golenbock, Douglas T..
(2003)
Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction.
Journal of Biological Chemistry
Academic article
-
Schjetne, KW;
Thompson, KM;
Nilsen, Nadra;
Flo, Trude Helen;
Fleckenstein, B;
Iversen, JG;
Espevik, Terje;
Bogen, B.
(2003)
Cutting edge: link between innate and adaptive immunity: Toll-like receptor 2 internalizes antigen for presentation to CD4+ T cells and could be an efficient vaccine target.
Journal of Immunology
Academic article
-
Rokstad, Anne Mari Aukan;
Strand, Berit Løkensgard;
Rian, K.;
Steinkjer, Bjørg;
Kulseng, Bård Eirik;
Skjåk-Bræk, Gudmund;
Espevik, Terje.
(2003)
Evaluation of different types of alginate microcapsules as bioreactors for producing endostatin.
Cell Transplantation
Academic article
-
Latz, E;
Visintin, A;
Lien, E;
Fitzgerald, KA;
Espevik, Terje;
Golenbock, DT.
(2003)
The LPS receptor generates inflammatory signals from the cell surface.
Journal of Endotoxin Research
Academic article
-
Strand, Berit Løkensgard;
Mørch, Yrr Asbjørg;
Espevik, Terje;
Skjåk-Bræk, Gudmund.
(2003)
Visualization of alginate-poly-L-lysine-alginate microcapsules by confocal laser scanning microscopy.
Biotechnology and Bioengineering
Academic article
-
Strand, Berit Løkensgard;
Mørch, Yrr Asbjørg;
Syvertsen, Kjersti R.;
Espevik, Terje;
Skjåk-Bræk, Gudmund.
(2003)
Microcapsules made by enzymatically tailored alginate.
Journal of Biomedical Materials Research
Academic article
-
Mori, Y;
Yoshimura, A;
Ukai, T;
Lien, Egil;
Espevik, Terje;
Hara, Y.
(2003)
Immunohistochemical localization of Toll-like receptors 2 and 4 in gingival tissue from patients with periodontitis.
Oral Microbiology and Immunology
Academic article
-
Adib-Conquy, M;
Moine, P;
Asehnoune, K;
Edouard, A;
Espevik, Terje;
Miyake, K;
Werts, C;
Cavaillon, J-M.
(2003)
Toll-like receptor-mediated tumor necrosis factor and interleukin-10 production differ during systemic inflammation.
American Journal of Respiratory and Critical Care Medicine
Academic article
-
Schjetne, KW;
Thompson, Keith;
Fleckenstein, Burkhard;
Aarvak, Tanja;
Flo, T. H.;
Iversen, Jens Gustav;
Espevik, T;
Bogen, Bjarne.
(2003)
Cutting edge: Link between innate and adaptive immunity: toll like receptor 2 (TLR 2) captures antigen for MHC class II presentation to CD4+ T cell responses.
Journal of Immunology
Academic article
2002
-
Dybdahl, Brit;
Lien, Egil;
Flo, Trude Helen;
Espevik, Terje;
Sundan, Anders;
Wahba, Alexander;
Sellevold, Olav F Münter.
(2002)
Heat Shock Proteins and Endotoxin Combined as a Trigger for Inflammatory Cytokine Release During Cardiopulmonary Bypass: A Possible Third Way? Letter til artikkel.
Circulation
Academic article
-
Flo, Trude Helen;
Ryan, Liv;
Latz, Eicke;
Takeuchi, Osamu;
Monks, Brian G.;
Lien, Egil;
Halaas, Øyvind;
Akira, Shizuo;
Skjåk-Bræk, Gudmund;
Golenbock, Douglas T..
(2002)
Involvement of toll-like receptor (TLR) 2 and TLR4 in cell activation by mannuronic acid polymers.
Journal of Biological Chemistry
Academic article
-
Rokstad, Anne Mari Aukan;
Holtan, Synnøve;
Strand, Berit Løkensgard;
Steinkjer, Bjørg;
Ryan, Liv;
Kulseng, Bård Eirik;
Skjåk-Bræk, Gudmund;
Espevik, Terje.
(2002)
Microencapsulation of cells producing therapeutic proteins: Optimizing cell growth and secretion.
Cell Transplantation
Academic article
-
Strand, Berit Løkensgard;
Gåserød, Olav;
Kulseng, Bård Eirik;
Espevik, Terje;
Skjåk-Bræk, Gudmund.
(2002)
Alginate-polylysine-alginate microcapsules – effect of size reduction on capsule properties.
Journal of Microencapsulation
Academic article
-
Liabakk, Nina-Beate;
Sundan, Anders;
Torp, Sverre Helge;
Aukrust, Pål;
Frøland, Stig Sophus;
Espevik, Terje.
(2002)
Development, characterization and use of monoclonal antibodies against sTRAIL measurement of sTRAIL by ELISA.
Journal of Immunological Methods (JIM)
Academic article
-
Kleij, D van der;
Latz, Eicke;
Brouwers, JF;
Kruize, YC;
Schmitz, M;
Kurt-Jones, EA;
Espevik, Terje;
Jong, EC de;
Kapsenberg, ML;
Golenbock, Douglas T..
(2002)
A novel host-parasite lipid cross-talk. Schistosomal lyso-phosphatidylserine activates Toll-like recepytor 2 and affects immune polarization.
Journal of Biological Chemistry
Academic article
-
Ellingsen, E.A.;
Morath, S;
Flo, Trude Helen;
Schromm, Andra;
Hartung, T;
Thiemermann, C;
Espevik, Terje;
Golenbock, Douglas T.;
Foster, D;
Solberg, R..
(2002)
Induction of cytokine production in human T cells and monocytes by highly purified lipoteichoic acid: involvement of Toll-like receptors and CD14.
Medical Science Monitor
Academic article
-
Dybdahl, Brit;
Wahba, Alexander;
Lien, Egil;
Flo, Trude Helen;
Waage, Anders;
Sellevold, Olav F Münter;
Espevik, Terje;
Sundan, Anders;
Qureshi, Nilofer.
(2002)
Inflammatory response after open heart surgery: release of heat-shock protein 70 and signaling through toll-like receptor-4.
Circulation
Academic article
-
Latz, Eicke;
Visintin, A;
Lien, Egil;
Fitzgerald, KA;
Monks, Brian G.;
Kurt-Jones, EA;
Golenbock, Douglas T.;
Espevik, Terje.
(2002)
Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the Toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction.
Journal of Biological Chemistry
Academic article
-
Belge, KU;
Dayyani, F;
Horelt, A;
Siedlar, M;
Frankenberger, M;
Frankenberger, B;
Espevik, Terje;
Ziegler-Heitbrock, L.
(2002)
The proinflammatory CD14+CD16+DR++ monocytes are a major source of TNF.
Journal of Immunology
Academic article
-
Tamai, Riyoko;
Sakuta, T;
Matsushita, K;
Torii, M;
Takeuchi, Osamu;
Akira, Shizuo;
Akashi, Sachiko;
Espevik, Terje;
Sugawara, Shunji;
Takada, Haruhiko.
(2002)
Human gingival CD14(+) fibroblasts primed with gamma interferon increase production of interleukin-8 in response to lipopolysaccharide through up-regulation of membrane CD14 and MyD88 mRNA expression.
Infection and Immunity
Academic article
2001
-
Lien, Egil;
Chow, Jesse C.;
Hawkins, Lynn D.;
McGuinness, Pamela D.;
Miyake, Kensuke;
Espevik, Terje;
Gusovsky, Fabian;
Golenbock, Douglas T..
(2001)
A novel synthetic acyclic lipid A-like agonist activates cells via the lipopolysaccharide/Toll-like receptor 4 signaling pathway.
Journal of Biological Chemistry
Academic article
-
Wang, J;
Warris, A;
Ellingsen, E.A.;
Jorgensen, P.F.;
Flo, Trude Helen;
Espevik, Terje;
Solberg, R.;
Verweij, P.E.;
Aasen, A. O..
(2001)
Involvement of CD14 and toll-like receptors in activation of human monocytes by Aspergillus fumigatus hyphae.
Infection and Immunity
Academic article
-
Liabakk, Nina-Beate;
Sundan, Anders;
Torp, Sverre Helge;
Aukrust, Pål;
Frøland, Stig;
Espevik, Terje.
(2001)
Development, characterization and use of monclonal antibodies against Strail: Measurement of Strail by Elisa.
Journal of Immunological Methods (JIM)
Academic article
-
Liabakk, Nina-Beate;
Waage, Anders;
Lien, Egil;
Stenvik, Jørgen;
Espevik, Terje.
(2001)
Cytokine bioassays.
Methods in Molecular Medicine
Academic article
-
Flo, Trude Helen;
Halaas, Øyvind;
Torp, Sverre Helge;
Ryan, Liv;
Lien, Egil;
Dybdahl, Brit;
Sundan, Anders;
Espevik, Terje.
(2001)
Differential expression of Toll-like receptor 2 in human cells.
Journal of Leukocyte Biology
Academic article
-
Flo, Trude Helen;
Ryan, Liv;
Kilaas, L;
Skjåk-Bræk, Gudmund;
Ingalls, Robin;
Sundan, Anders;
Golenbock, D;
Espevik, Terje.
(2001)
The involvement of CD14 and beta2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers.
Infection and Immunity
Academic article
-
Rokstad, Anne Mari Aukan;
Kulseng, Bård Eirik;
Strand, Berit Løkensgard;
Skjåk-Bræk, Gudmund;
Espevik, Terje.
(2001)
Transplantation of alginate microcapsules with proliferating cells in mice. Capsular overgrowth and suvival of encapsulated cells of mice and human origin.
Annals of the New York Academy of Sciences
Academic article
-
Strand, Berit Løkensgard;
Ryan, Liv;
Veld, Peter Int;
Kulseng, Bård Eirik;
Rokstad, Anne Mari Aukan;
Skjåk-Bræk, Gudmund;
Espevik, Terje.
(2001)
Poly-L-Lysine Induces Fibrosis on Alginate Microcapsules via the Induction of Cytokines.
Cell Transplantation
Academic article
-
Jenssen, Jon A;
Espevik, Terje.
(2001)
Cellebiologisk metode for å påvise biologisk aktivitet av svevestøv.
SINTEF AS
Research report
-
Iversen, Ann-Charlotte;
Sundan, Anders;
Espevik, Terje.
(2001)
IFN-alpha(2b) and IFN-beta induce TRAIL-mediated NK cell cytotoxicity.
The FASEB Journal
Conference abstract
-
Sugawara, Shunji;
Yang, Shuhua;
Iki, Koichi;
Hatakeyama, Junko;
Tamai, Riyoko;
Takeuchi, Osamu;
Akashi, Sachiko;
Espevik, Terje;
Akira, Shizuo;
Takada, Haruhiko.
(2001)
Monocytic cell activation by nonendotoxic glycoprotein from Prevotella intermedia ATCC 25611 is mediated by Toll-like receptor 2.
Infection and Immunity
Academic article
-
Henneke, Philipp;
Takeuchi, Osamu;
Strijp, JA van;
Guttormsen, HK;
Smith, JA;
Schromm, Andra;
Espevik, Terje;
et, al..
(2001)
Novel engagement of CD14 and multiple toll-like receptors by group B streptococci.
Journal of Immunology
Academic article
2000
-
Falch, Berit H.;
Espevik, Terje;
Ryan, Liv;
Stokke, Bjørn Torger.
(2000)
The cytokine stimulating activity of (1->3)-_B-D-glucans is dependent on the triple helix conformation.
Carbohydrate Research
Academic article
-
Espevik, Terje;
Waage, Anders;
Sundan, Anders.
(2000)
Summary of the 8th International TNF Congress, Trondheim, May 14-18, 2000.
STENS trykkeri
Research report
-
Skjåk-Bræk, Gudmund;
Flo, Trude Helen;
Halaas, Øyvind;
Espevik, Terje.
(2000)
Immune stimulating properties of di-equatorially beta(1->4) linked poly-uronides.
Proceedings of the Phytochemical Society of Europe
Academic article
-
Cuzzola, M.;
Mancuso, G.;
Beninati, C.;
Biondo, C.;
Genovese, F.;
Tomasello, F.;
Flo, Trude Helen;
Espevik, Terje;
Teti, G..
(2000)
_B2 integrins are involved in cytokine responses to whole gram-positive bacteria.
Journal of Immunology
Academic article
-
Flo, Trude Helen;
Ryan, Liv;
Kilaas, Lars;
Skjåk-Bræk, Gudmund;
Ingalls, Robin R.A;
Sundan, Anders;
Golenbock, Douglas T.;
Espevik, Terje.
(2000)
Involvement of CD14 and _B2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers.
Infection and Immunity
Academic article
-
Cuzzola, Maria;
Mancuso, Guiseppe;
Beninati, Concetta;
Biondo, Carmelo;
Hunolstein, Christina von;
Orefici, Graziella;
Espevik, Terje;
Flo, Trude Helen;
Teti, Guisseppe.
(2000)
Human monocyte receptors involved in tumor necrosis factor responses to group B streptococcal products.
Infection and Immunity
Academic article
-
Lien, E.;
Espevik, Terje.
(2000)
Toll-lignende reseptorer - kroppens sensorer for infeksjon.
NBS-nytt
Popular science article
-
Espevik, Terje;
Waage, Anders;
Sundan, A..
(2000)
Summary of the 8 th International TNF Congress. Trondheim.
NBS-nytt
Non-fiction monograph
-
Flo, T.H.;
Ryan, L.;
Kilaas, L.;
Skjåk-Bræk, Gudmund;
Ingalls, R.R.;
Sundan, A.;
Golenbock, D.T.;
Espevik, Terje.
(2000)
Involvement of CD14 and beta2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers.
Infection and Immunity
Academic article
-
Flo, Trude Helen;
Halaas, Øyvind;
Lien, Egil;
Ryan, Liv;
Teti, Guiseppe;
Golenbock, Douglas T.;
Sundan, Anders;
Espevik, Terje.
(2000)
Human Toll-like Receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide.
Journal of Immunology
Academic article
1999
-
Lien, Egil;
Sellati, Timothy J.;
Yoshimura, Atsutosi;
Flo, Trude Helen;
Rawadi, Georges;
Finberg, Robert W.;
Caroll, J.David;
Espevik, Terje;
Ingalls, Robin R;
Radolf, Justin D..
(1999)
Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products.
Journal of Biological Chemistry
Academic article
-
Kulseng, Bård Eirik;
Vatten, Lars Johan;
Espevik, Terje.
(1999)
Soluble tumor necrosis factor receptors in sera from patients with insulin-dependent diabetes mellitus: relations to duration and complications of disease.
Acta Dermato-Venereologica
Academic article
-
Børset, Magne;
Hjort-Hansen, Henrik;
Johnsen, Ann-Charlotte;
Seidel, Carina;
Waage, Anders;
Espevik, Terje;
Sundan, Anders.
(1999)
Apoptosis, proliferation and NF-k(kappa)B activation induced by agonistic Fas antibodies in the human myeloma cell line OH-2: amplification of Fas-mediated apoptosis by tumor necrosis factor.
European Journal of Haematology
Academic article
-
Aukrust, Pål;
Haug, Charlotte J.;
Ueland, Thor;
Lien, Egil;
Müller, Fredrik;
Espevik, Terje;
Bollerslev, Jens;
Frøland, Stig S..
(1999)
Decreased bone formative and enhanced resorptive markers in human immunodeficiency virus infection: Indication of normalization of the bone-remodeling process during highly active antiretroviral therapy.
Journal of Clinical Endocrinology and Metabolism (JCEM)
Academic article
-
Aukrust, Pål;
Müller, Fredrik;
Lien, Egil;
Nordøy, Ingvild;
Liabakk, Nina-Beate;
Kvale, Dag;
Espevik, Terje;
Frøland, Stig S..
(1999)
Tumor necrosis factor (TNF) system levels in human immunodificiency virus-infected patients during highly active antiretroviral therapy: Perisistent TNF activation is associated with virologic and immunologic treatment failure.
Journal of Infectious Diseases
Academic article
-
Kulseng, Bård Eirik;
Skjåk-Bræk, Gudmund;
Ryan, Liv;
Andersson, Arne;
King, Aileen;
Faxvaag, Arild;
Espevik, Terje.
(1999)
Transplantation of alginate microcapsules.
Transplantation
Academic article
-
Iversen, Ann-Charlotte;
Johnsen, Ann-Charlotte;
Haux, Johan;
Steinkjer, Bjørg;
Nonstad, Unni;
Egeberg, Kjartan Wøllo;
Sundan, Anders;
Ashkenazi, Avi;
Espevik, Terje.
(1999)
Regulation of Apo-2 Ligand/Trail expression in NK cells - Involvement in NK cell mediated cytotoxicity.
Cytokine
Academic article
-
Haux, Johan;
Iversen, Ann-Charlotte;
Johnsen, Ann-Charlotte;
Steinkjer, Bjørg;
Egeberg, Kjartan Wøllo;
Sundan, Anders;
Espevik, Terje.
(1999)
The role of IL-2 in regulating the sensitivity of NK cells for Fas-mediated apoptosis.
Cancer Immunology and Immunotherapy
Academic article
-
Kulseng, Bård Eirik;
Skjåk-Bræk, Gudmund;
Ryan, Liv;
Andersson, Arne;
King, Aileen;
Faxvaag, Arild;
Espevik, Terje.
(1999)
Transplantation of alginate microcapsules. Generation of antibodies against alginates and encapsulated porcine islet-like cell clusters.
Transplantation
Academic article
-
Heine, Holger;
Delude, Russell L.;
Monks, Biran G.;
Espevik, Terje;
Golenbock, Douglas T..
(1999)
Bacterial lipopolysaccharide induces expression of the stress response genes Hop and H411.
Journal of Biological Chemistry
Academic article
-
Gullestad, Lars;
Aukrust, Pål;
Ueland, Thor;
Espevik, T;
Yee, G.;
Vagelos, R.;
Frøland, Stig Sophus;
Fowler, M.B..
(1999)
Effect of high- versus low-dose angiotensin converting enzyme inhibition on cytokine levels in chronic heart failure.
Journal of the American College of Cardiology
Academic article
-
Johnsen, A-C;
Steinkjer, B;
Egeberg, Kathrine;
Sundan, A;
Espevik, Terje.
(1999)
The role of international-2 in regulation the sensitivity of natural killer celler for Fas-mediated apoptosis.
European Journal of Haematology
Academic article
-
Lien, E;
Nonstad, Unni;
Sundan, A;
Espevik, Terje.
(1999)
Polymorphonuchlear of Fas and Fas-Ligand expression in NK cells by cytokines and the involved of Fas-Ligand in NK/LAK cell-mediated cytotoxicity.
Cytokine
Academic article
-
Aukrust, Pål;
Muller, Fredrik;
Lien, Egil;
Nordøy, Ingvild;
Liabakk, Nina-Beate;
Kvale, Dag;
Espevik, T;
Frøland, Stig Sophus.
(1999)
Tumor necrosis factor (TNF) system in human immunodeficiency virus-infected patients during highly active antiretroviral therapy (HAART): Persistent TNF activation is associated with virologic and immunologic treatment failure.
Journal of Infectious Diseases
Academic article
-
Aukrust, Pål;
Haug, Charlotte J.;
Ueland, Thor;
Lien, Egil;
Muller, Fredrik;
Espevik, T;
Bollerslev, Jens;
Frøland, Stig Sophus.
(1999)
Decreased bone formative and enhanced resorptive markers in human immunodeficiency virus infection: indication of normalization of the bone-remodeling process during highly active antiretroviral therapy.
Journal of Clinical Endocrinology and Metabolism (JCEM)
Academic article
-
Aukrust, Pål;
Ueland, Thor;
Lien, Egil;
Bendtzen, Klaus;
Muller, Fredrik;
Andreassen, Arne K.;
Nordøy, Ingvild;
Aass, Halfdan;
Espevik, T;
Simonsen, Svein.
(1999)
Cytokine network in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy.
American Journal of Cardiology
Academic article
-
Kulseng, Bård Eirik;
Espevik, Terje;
Skjåk-Bræk, Gudmund.
(1999)
Behandling av diabetes mellitus med transplantasjon av immunbeskyttet øyvev fra pancreas.
Tidsskrift for Den norske legeforening (Tidsskriftet)
Academic article
-
Johnsen, Ann-Charlotte;
Haux, Johan;
Steinkjer, Bjørg;
Nonstad, Unni;
Egeberg, Kjartan Wøllo;
Sundan, Anders;
Ashkenazi, Avi;
Espevik, Terje.
(1999)
Regulation of APO-2 ligand /Trail expression in NK cells - involvement in NK cell-mediated cytotoxicity.
Cytokine
Academic article
1998
-
Lien, Egil;
Aukrust, Pål;
Sundan, Andreas;
Muller, Fredrik;
Frøland, Stig Sophus;
Espevik, T.
(1998)
Elevated levels of serum-soluble CD14 in human immonudeficiency virus type 1 (HIV-1) infection: correlation to disease progression and clinical events.
Blood
Academic article
-
Ingalls, RR;
Monks, BG;
R, [Mangler fornavn] Savedra;
Christ, WJ;
Delude, RL;
Medvedev, AE;
Espevik, Terje;
Golenbock, DT.
(1998)
CD11/CD18 and CD14 share a common lipid A signaling pathway.
Journal of Immunology
Academic article
-
Thommesen, Liv;
Sjursen, Wenche;
Gåsvik, Kathrine;
Hanssen, Wenche;
Brekke, Ole-Lars;
Skattebøl, Lars;
Holmeide, Anne Kristin;
Espevik, Terje;
Johansen, Berit;
Lægreid, Astrid.
(1998)
Selective inhibitors of cytosolic or secretory phospholipase A2 block TNF-induced activation of transcription factor nuclear factor-kappa B and expression of ICAM-1.
Journal of Immunology
Academic article
-
Medvedev, AE;
Flo, T;
Vogel, SN;
Robin, R;
Golenbock, DT;
Teti, G;
Espevik, Terje.
(1998)
Involvement of CD14 and complement receptors CR3 and CR4 in nuclear factor-kappaB activation and TNF production induced by lipopolysaccharide and group B streptococcal cell walls.
Journal of Immunology
Academic article
-
Halaas, Øyvind;
Vik, R;
Espevik, Terje.
(1998)
Induction of Fas ligand in murine bone marrow NK cells by bacterial polysaccharides.
Immunology
Academic article
-
Iversen, Ann-Charlotte;
Johnsen, Ann-Charlotte;
Haux, Johan;
Steinkjer, Bjørg;
Nonstad, Unni;
Egeberg, Kjartan Wøllo;
Ashkenazi, Avi;
Sundan, Anders;
Espevik, Terje.
(1998)
Regulation of Apo-2 Ligand/TRAIL expression in NK cells - Involvement in NK cell mediated cytotoxicity.
Journal of Interferon and Cytokine Research
Conference abstract
-
Lien, E;
Sundan, A;
Aukrust, P;
Frøland, S;
Espevik, Terje.
(1998)
Elevated levels of serum-soluble CD14 in human immunodeficiency virus type 1 (HIV-1) infection: correlation to disease progression and clinical events.
Blood
Academic article
-
Kulseng, Bård Eirik;
Espevik, Terje;
Sundan, A.
(1998)
Elevated hepatocyte growth factor in sera from patients with insulin-dependent diabetes mellitus.
Acta Dermato-Venereologica
Academic article
-
Berntzen, G.;
Flo, T;
Medvedev, A;
Kilaas, L;
Skjåk-Bræk, Gudmund;
Sundan, A;
Espevik, Terje.
(1998)
The tumor necrosis factor-inducing potency of lipopolysaccharide and uronic acid polymers is increased when they are covalently linked to particles.
Clinical and Vaccine Immunology
Academic article
1997
-
Sandler, Stellan;
Andersson, Arne;
Eizirik, Décio L.;
Hellerström, Claes;
Espevik, Terje;
Kulseng, Siri;
Thu, Beate;
Pipeleers, Daniel G.;
Skjåk-Bræk, Gudmund.
(1997)
Assessment of insulin secretion in vitro from microencapsulated fetal procine islet-like cell clusters and rat, mouse, and human pancreatic islets.
Transplantation
Academic article
-
Kulseng, Bård Eirik;
Thu, Beate;
Espevik, Terje;
Skjåk-Bræk, Gudmund.
(1997)
Alginate polylysine microcapsules as immune barrer : permeability of cytokines and immmunoglobulins over the capsule membrane.
Cell Transplantation
Academic article
-
Jackson, A.M.;
Lien, Egil;
Alexandroff, A.B.;
Espevik, Terje;
James, K.;
Selby, P.J.;
Sundan, Anders.
(1997)
Soluble urinary CD14 after intravesical bacille Calmette-Guérin immunotherapy for carcinoma in situ.
British Journal of Urology
Academic article
-
Medvedev, Andrei E.;
Iversen, Ann-Charlotte;
Johnsen, Ann-Charlotte;
Haux, Johan;
Steinkjer, Bjørg;
Egeberg, Kjartan Wøllo;
Lynch, David H.;
Sundan, Anders;
Espevik, Terje.
(1997)
Regulation of Fas and Fas-Ligand expression in NK cells by cytokines and the involvement of Fas-Ligand in NK/LAK cell-mediated cytotoxicity.
Cytokine
Academic article
-
Aukrust, Pål;
Hestdal, Ketil;
Lien, Egil;
Bjerkeli, Vigdis;
Nordøy, Ingvild;
Espevik, Terje;
Myller, Stig;
Frøland, S..
(1997)
Effects of intravenous immunoglobulin in vivo on abnormally increased tumor necrosis factor-alpha activity in human immunodeficiency virus type 1 infection.
Journal of Infectious Diseases
Academic article
-
Hestdal, Kjetil;
Aukrust, Pål;
Müller, Fredrik;
Lien, Egil;
Bjerkeli, Vigdis;
Espevik, Terje;
Frøland, Stig S..
(1997)
Dysregulation of membrane-bound tumor necrosis factor-_a and tumor necrosis factor receptors on mononuclear cells in human immunodeficiency virus type 1 infection : low percentage of p75-tumor necrosis factor receptor positive cells in patients with advanced disease and high viral load.
Blood
Academic article
-
Jahr, Tove Gullstein;
Ryan, Liv;
Sundan, Anders;
Lichenstein, Henri S.;
Skjåk-Bræk, Gudmund;
Espevik, Terje.
(1997)
Induction of tumor necrosis factor production from monocytes stimulated with mannuronic acid polymers and involvement of lipopolysaccharide-binding protein, CD14, and bactericidal/ permeability-increasing factor.
Infection and Immunity
Academic article
-
Aukrust, Pål;
Hestad, Kjetil;
Lien, Egil;
Bjerkeli, Vigdis;
Nordøy, Ingvild;
Espevik, T;
Muller, Fredrik;
Frøland, Stig Sophus.
(1997)
Effects of intravenous immunoglobulin in vivo on abnormally increased tumor necrosis factor-_a activity in human immunodeficiency virus type 1 infection.
Journal of Infectious Diseases
Academic article
-
Hestad, Kjetil;
Aukrust, Pål;
Muller, Fredrik;
Lien, Egil;
Bjerkeli, Vigdis;
Espevik, T;
Frøland, Stig Sophus.
(1997)
Dysregulation of membrane-bound tumor necrosis factor-_a and tumor necrosis factor receptors on mononuclear cells in human immunodeficiency virus type 1 infection: Low percentage of p75-tumor necrosis factor receptor positive cells in patients with advanced disease and high viral load.
Blood
Academic article
1996
-
Thu, Beate;
Bruheim, Per;
Espevik, Terje;
Smidsrød, Olav;
Soon-Shiong, Patrick;
Skjåk-Bræk, Gudmund.
(1996)
Alginate polycation microcapsules. II, Some functional properties.
Biomaterials
Academic article
-
Haug, Charlotte J.;
Aukrust, Pål;
Lien, Egil;
Muller, Fredrik;
Espevik, T;
Frøland, Stig Sophus.
(1996)
Disseminated Mycobacterium avium complex (MAC) infection in AIDS: Immunopathogenic significance of an activated tumor necrosis factor (TNF) system and depressed serum levels of 1,25-dihydroxyvitamin D.
Journal of Infectious Diseases
Academic article
-
Aukrust, Pål;
Lien, Egil;
Kristoffersen, Anne Karin;
Muller, Fredrik;
Haug, Charlotte J.;
Espevik, T;
Frøland, Stig Sophus.
(1996)
Persistant Activation of The Tumor Nevcrosis Factor System in a Subgroup of Patients With Common Varable Immunodeficincy - Possible Immunological and Clinical and Consequences.
Blood
Academic article
-
Aukrust, Pål;
Lien, Egil;
Kristoffersen, Anne Karin;
Muller, Fredrik;
Haug, Charlotte J.;
Espevik, T;
Frøland, Stig Sophus.
(1996)
Persistent activation of tumor necrosis factor system in a subgroup of patients with common variable immunodeficiency - Possible immunologic and clinical concensus.
Blood
Academic article
-
Haug, Charlotte J.;
Aukrust, Pål;
Lien, Egil;
Müller, Fredrik;
Espevik, Terje;
Frøland, Stig S..
(1996)
Disseminated Mycobacterium avium complex infection in AIDS : immunopathogenic significance of an activated tumor necrosis factor system and depressed serum levels of 1,25 dihydroxyvitamin D.
Journal of Infectious Diseases
Academic article
-
Medvedev, Andrei E.;
Espevik, Terje;
Ranges, Gerald;
Sundan, Anders.
(1996)
Distinct roles of the two tumor necrosis factor (TNF) receptors in modulating TNF and lymphotoxin _a effects.
Journal of Biological Chemistry
Academic article
-
Medvedev, Andrei E.;
Lægreid, Astrid;
Sundan, Anders;
Espevik, Terje.
(1996)
A non-competitive P55 TNF receptor antibody enhances the specific activity of Lymphotoxin-_a.
Scandinavian Journal of Immunology
Academic article
-
Skjåk-Bræk, Gudmund;
Espevik, Terje.
(1996)
Application of alginate gels in biotechnology and biomedicine.
Carbohydrates in Europe
Academic article
-
Kulseng, Bård Eirik;
Skjåk-Bræk, Gudmund;
Følling, Ivar;
Espevik, Terje.
(1996)
TNF production from peripheral blood mononuclear cells in diabetic patients after stimulation with alginate and lipopolysaccharide.
Scandinavian Journal of Immunology
Academic article
-
Thu, Beate;
Bruheim, Per;
Espevik, Terje;
Smidsrød, Olav;
Soon-Shiong, P.;
Skjåk-Bræk, Gudmund.
(1996)
Alginate polycation microcapsules. I, Interaction between alginate and polycation.
Biomaterials
Academic article
-
Børset, Magne;
Medvedev, Andrei E.;
Sundan, Anders;
Espevik, Terje.
(1996)
The role of the two TNF receptors in proliferation, NF-_KB activation and discrimination between TNF and LT_a signalling in the human myeloma cell line OH-2.
Cytokine
Academic article
-
Børset, Magne;
Lien, Egil;
Espevik, Terje;
Helseth, Eirik;
Waage, Anders;
Sundan, Anders.
(1996)
Concomitant expression of hepatocyte growth factor/scatter factor and the receptor c-MET in human myeloma cell lines.
Journal of Biological Chemistry
Academic article
-
Aukrust, Pål;
Lien, Egil;
Kristoffersen, Anne K.;
Müller, Fredrik;
Haug, Charlotte J.;
Espevik, Terje;
Frøland, Stig S..
(1996)
Persistent activation of the tumor necrosis factor system in a subgroup of patients with common variable immunodeficiency : possible immunologic and clinical consequences.
Blood
Academic article
1995
-
Skjermo, Jorunn;
Defoort, Thomas;
Dehasque, Marleen;
Espevik, Terje;
Olsen, Yngvar;
Skjåk-Bræk, Gudmund;
Sorgeloost, Patrick;
Vadstein, Olav.
(1995)
Immunostimulation of juvenile turbot (Scophthalmus maximus L.) using an alginate with high mannuronic acid content administered via the live food organism Artemia.
Fish and Shellfish Immunology
Academic article
-
Samuelsen, Anne Berit;
Paulsen, Berit Smestad;
Wold, Jens Krisitian;
Otsuka, Hanako;
Yamada, Haruki;
Espevik, T.
(1995)
Isolation and partial characterization of biologically active polysaccharides from Plantago major L.
Phytotherapy Research
Academic article
-
Lien, Egil;
Liabakk, Nina-Beate;
Iversen, Ann-Charlotte;
Johnsen, Ann-Charlotte;
Nonstad, Unni;
Sundan, Anders;
Espevik, Terje.
(1995)
Polymorphonuclear granulocytes enhance lipopolysaccharide-induced p75 tumor necrosis factor receptor release from mononuclear cells.
European Journal of Immunology
Academic article
-
Arntzen, KJ;
Liabakk, N-B;
Jacobsen, G.;
Espevik, Terje;
Austgulen, Rigmor.
(1995)
Soluble tumor necrosis factor receptor in serum and urine througout normal pregnancy and delivery.
American Journal of Reproductive Immunology
Academic article
-
Skjåk-Bræk, Gudmund;
Espevik, Terje;
Otterlei, Marit;
Smidsrød, Olav;
Soon-Shiong, P..
(1995)
Homologous guluronic acid alginate coating composition for in vivo application and implantation and method using the same.
[Mangler utgivernavn]
Research report
1994
-
Brekke, OL;
Espevik, Terje;
Bjerve, Kristian S.
(1994)
Butylated Hydroxyanisole Inhibits Tumor Necrosis Factor induced Cytotoxicity and Arachidonic Acid Release.
Lipids
Academic article
-
Halgunset, J;
Johnsen, H;
Kjøllesdal, AM;
Qvigstad, E;
Espevik, Terje;
Austgulen, Rigmor.
(1994)
Normal parturition at term is associated with subtle inflammatory reactions in-utero.
European Journal of Obstetrics, Gynecology, and Reproductive Biology
Academic article
-
Waage, A.;
Halstensen, Alfred;
Espevik, T.;
Brandtzæg, P..
(1994)
Cytokines in meningococcal disease.
Baillière's Clinical Infectious Diseases
Academic article
1993
-
Naume, Bjørn;
Iversen, Ann-Charlotte;
Johnsen, Ann-Charlotte;
Espevik, Terje;
Sundan, Anders.
(1993)
Gene expression and secretion of cytokines and cytokine receptors from hihgly purified CD56+ natural killer cells stimulated with interleukin-2, interleukin-7 and interleukin-12.
European Journal of Immunology
Academic article
-
Austgulen, Rigmor;
Naume, B;
Johnson, A-C;
Espevik, Terje;
Sundan, A.
(1993)
Gene expression and secretion of cytokines and cytokines from highly purified CD56* natural killer cells stimulated with interleukin-2, interleukin-7 and interleukin-12.
European Journal of Immunology
Academic article
-
Austgulen, Rigmor;
Kjøllesdal, AM;
Johnsen, H;
Liabakk, N-B;
Espevik, Terje.
(1993)
Soluble receptors for tumor necrosis factor: occurence in association with normal delivery at term.
Obstetrics and Gynecology
Academic article
-
Austgulen, Rigmor;
Liabakk, N-B;
Lien, E;
Espevik, Terje.
(1993)
Increased levels of soluble TNF-alpha receptors in serum from pregnant women, and in serum and urine samples from newborns.
Pediatric Research
Academic article
-
Liabakk, N-B;
Lien, E;
Sundan, A;
Sunde, A;
Austgulen, Rigmor;
Espevik, Terje.
(1993)
High concentrations of the soluble p55 tumor necrosis factor receptor in human seminal plasma.
Human Reproduction
Academic article
-
Austgulen, Rigmor;
Liabakk, N-B;
Richardsen, W;
Rahimipoor, S;
Vatn, I;
Espevik, Terje.
(1993)
Serum levels of soluble TNF receptors are influenced by gestational age and delivery in normal pregnancy.
Placenta
Conference abstract
-
Waage, A.;
Halstensen, Alfred;
Espevik, T.;
Brandtzæg, P..
(1993)
Compartmentalization of the TNF and IL-6 in meningitis and septic shock.
Mediators of Inflammation
Academic article
1992
-
Brekke, OL;
Espevik, Terje;
Bardal, Tora;
Bjerve, Kristian S.
(1992)
Effects of n-3 and n-6 fatty acids on Tumor Necrosis Factor cytotoxicity in WEHI fibrosarcoma cells.
Lipids
Academic article
-
Brekke, OL;
Shalaby, MR;
Sundan, Anders;
Espevik, Terje;
Bjerve, Kristian S.
(1992)
Butylated hydroxyanisol specifically inhibits Tumor Necrosis Factor induced cytotoxicity and growth enhancement.
Cytokine
Academic article
-
Austgulen, Rigmor;
Liabakk, NB;
Brockhaus, M;
Espevik, Terje.
(1992)
Soluble TNF receptors in amniotic fluid and in urine from pregnant women.
Journal of Reproductive Immunology
Academic article
-
Soon-Shong, P.;
Feldman, E.;
Nelson, R.;
Komtebedde, J.;
Smidsrød, Olav;
Skjåk-Bræk, Gudmund;
Espevik, Terje;
Heintz, R.;
Lee, M..
(1992)
Successful reversal of spontaneous diabetes in dogs by intraperitonal microencapsulated islets.
Transplantation
Academic article
-
Waage, A.;
Halstensen, Alfred;
Brandtzæg, P.;
Espevik, T..
(1992)
TNF in serum in patients with bacterial infections.
Academic chapter
-
Austgulen, Rigmor;
Espevik, Terje;
Mecsei, R;
Scott, H.
(1992)
Expression of receptors for tumor necrosis factor in human placenta at term.
Acta Obstetricia et Gynecologica Scandinavica
Academic article
-
Austgulen, Rigmor;
Liabakk, N-B;
Espevik, Terje.
(1992)
Sekresjon av løselige reseptorer for tumor nekrose faktor - en immunologisk buffermekanisme under svangerskap?.
Tidsskrift for Den norske legeforening (Tidsskriftet)
Academic article
-
Brandtzæg, P.;
Halstensen, Alfred;
Kierulf, P.;
Espevik, T.;
Waage, A..
(1992)
Molecular mechanisms in the compartmentalized inflammatory response presenting as meningococcal meningitis or septic shock.
Microbial Pathogenesis
Academic article
1991
-
Waage, A.;
Brandtzæg, P.;
Espevik, T.;
Halstensen, Alfred.
(1991)
Current understanding of the pathogenesis of gram negative shock.
Infectious Disease Clinics of North America
Academic article
-
Austgulen, Rigmor;
Liabakk, N-B;
Scott, H;
Brockhaus, M;
Espevik, Terje.
(1991)
Soluble TNF receptors in urine and in amniotic fluid from pregnant women.
Placenta
Conference abstract
1988
-
Nissen-Meyer, J;
Hofsli, E;
Espevik, Terje;
Austgulen, Rigmor.
(1988)
Involvement of tumor necrosis factor in cytotoxicity mediated by human monocytes.
Natural immunity and cell growth regulation
Academic article
-
Nissen-Meyer, J;
Austgulen, Rigmor;
Espevik, Terje.
(1988)
Synergistic growth inhibitory activity of tumor necrosis factor and interferon-alpha: contribution to the monocyte-derived cytostatic activity towards human leukemia K562 cells.
Scandinavian Journal of Immunology
Academic article
1987
-
Bjerve, Kristian S;
Espevik, Terje;
Kildahl-Andersen, O;
Nissen-Meyer, J.
(1987)
Effect of free fatty acids on the cytolytic activity of tumor necrosis factor/¬monocyte-derived cytotoxic factor.
APMIS - Journal of Pathologiy, Microbiology and Immunology
Academic article
-
Nissen-Meyer, J;
Austgulen, Rigmor;
Espevik, Terje.
(1987)
Comparison of recombinant tumor necrosis factor and the monocyte-derived cytotoxic factor (CF) which is involved in the monocyte-mediated cytotoxicity.
Cancer Research
Academic article
-
Austgulen, Rigmor;
Espevik, Terje;
Nissen-Meyer, J.
(1987)
Fibroblast growth stimulatory activity from human monocytes: The contribution of tumor necrosis factor.
Scandinavian Journal of Immunology
Academic article
-
Austgulen, Rigmor;
Espevik, Terje;
Degree, M.
(1987)
Monocyte-derived influence on growth of normal human fibroblasts: The contribution of tumor necrosis factor to growth inhibition.
Scandinavian Journal of Immunology
Academic article
1986
-
Austgulen, Rigmor;
Hammerstrøm, J;
Espevik, Terje;
Nissen-Meyer, J.
(1986)
Human monocyte cytotoxic factor mediates cytolysis of WEHI 164 cells.
Cellular Immunology
Academic article
-
Austgulen, Rigmor;
Kildahl-Andersen, O;
Espevik, Terje.
(1986)
Monocyte-mediated drug-dependent cellular cytotoxicity: Effects of different WEHI 164 target cell lines.
Cancer Immunology and Immunotherapy
Academic article
-
Austgulen, Rigmor;
Espevik, Terje;
Hammerstrøm, J;
Nissen-Meyer, J.
(1986)
Role of monocyte cytotoxic factor in cytolysis of actinomycin D treated WEHI 164 cells mediated by freshly isolated human adherent mononuclear blood cells.
Cancer Research
Academic article
Journal publications
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Gravastrand, Caroline Saugestad;
Yurchenko, Maria;
Kristensen, Stine;
Skjesol, Astrid;
Chen, Carmen;
Ullmann, Sindre;
Iqbal, Zunaira;
Dahlen, Karoline Ruud;
Rasheed, Kashif;
Nonstad, Unni.
(2026)
GTPase Rab11b and effector Rab11-FIP2 promote NLRP3 stability during inflammasome priming.
EMBO Journal
Academic article
-
Camassa, Laura Maria Azzurra;
Elje, Elisabeth;
Shaposhnikov, Sergey;
Haugen, Kristine;
Skare, Øivind;
Espevik, Terje;
Nilsen, Asbjørn Magne;
Ryan, Liv;
Rundén-Pran, Elise;
Zienolddiny-Narui, Shan.
(2026)
Organ-specific in vitro models for prediction of hazard assessment of nanomaterials.
Toxicology in Vitro
Academic article
-
Rasheed, Kashif;
Nejati Moharrami, Neda;
Tande, Erlend Bjørkøy;
Espevik, Terje;
Yurchenko, Maria;
Boyartchuk, Victor.
(2026)
Endogenous CD5L controls the metabolic and inflammatory state of human macrophages.
Frontiers in Immunology
Academic article
-
Nilsen, Kaja Elisabeth;
Stenvik, Jørgen;
Skjesol, Astrid;
Mestvedt, Ingvild Bergdal;
Bakke, Siril Skaret;
Giambelluca, Miriam Soledad;
Gravastrand, Caroline Saugestad;
Elamurugan, Kirusika;
Ryan, Liv;
Espevik, Terje.
(2025)
A novel TIRAP-MyD88 inhibitor blocks TLR7- and TLR8-induced type I IFN responses.
Journal of Immunology
Academic article
-
Bye, Katja Sæterhaug;
Rian, Kristin;
Ryan, Liv;
Espevik, Terje;
Anthonsen, Marit Walbye;
Yurchenko, Maria.
(2025)
The immune receptors TLR4 and SLAMF1 regulate TNF release by human metapneumovirus in human macrophages.
Frontiers in Immunology
Academic article
-
Lien, Egil;
Chow, Jesse C.;
Hawkins, Lynn D.;
McGuinness, Pamela D.;
Miyake, Kensuke;
Espevik, Terje;
Gusovsky, Fabian;
Golenbock, Douglas T..
(2001)
A novel synthetic acyclic lipid A-like agonist activates cells via the lipopolysaccharide/Toll-like receptor 4 signaling pathway.
Journal of Biological Chemistry
Academic article
-
Dybdahl, Brit;
Lien, Egil;
Flo, Trude Helen;
Espevik, Terje;
Sundan, Anders;
Wahba, Alexander;
Sellevold, Olav F Münter.
(2002)
Heat Shock Proteins and Endotoxin Combined as a Trigger for Inflammatory Cytokine Release During Cardiopulmonary Bypass: A Possible Third Way? Letter til artikkel.
Circulation
Academic article
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Falch, Berit H.;
Espevik, Terje;
Ryan, Liv;
Stokke, Bjørn Torger.
(2000)
The cytokine stimulating activity of (1->3)-_B-D-glucans is dependent on the triple helix conformation.
Carbohydrate Research
Academic article
-
Lien, Egil;
Sellati, Timothy J.;
Yoshimura, Atsutosi;
Flo, Trude Helen;
Rawadi, Georges;
Finberg, Robert W.;
Caroll, J.David;
Espevik, Terje;
Ingalls, Robin R;
Radolf, Justin D..
(1999)
Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products.
Journal of Biological Chemistry
Academic article
-
Heggelund, L;
Muller, F;
Lien, E;
Yndestad, A;
Ueland, T;
Kristiansen, KI;
Espevik, Terje;
Aukrust, P;
Frøland, Stig Sophus;
Froland, SS.
(2004)
Increased expression of Toll-like receptor 2 on monocytes in HIV infection: Possible roles in inflammation and viral replication.
Clinical Infectious Diseases
Academic article
-
Espevik, Terje.
(2004)
Tolerance induced by the lipopeptide Pam3Cys is due to ablation of IL-1R-associated kinase-1.
Journal of Immunology
Academic article
-
Dybdahl, Brit;
Wahba, Alexander;
Haaverstad, Rune;
Kirkeby-Garstad, I.;
Kierulf, P;
Espevik, Terje;
Sundan, A.
(2004)
On-pump versus off-pump coronary artery bypass grafting: more heat-shock protein 70 is released after on-pump surgery.
European Journal of Cardio-Thoracic Surgery
Academic article
-
Wang, J;
Warris, A;
Ellingsen, E.A.;
Jorgensen, P.F.;
Flo, Trude Helen;
Espevik, Terje;
Solberg, R.;
Verweij, P.E.;
Aasen, A. O..
(2001)
Involvement of CD14 and toll-like receptors in activation of human monocytes by Aspergillus fumigatus hyphae.
Infection and Immunity
Academic article
-
Liabakk, Nina-Beate;
Sundan, Anders;
Torp, Sverre Helge;
Aukrust, Pål;
Frøland, Stig;
Espevik, Terje.
(2001)
Development, characterization and use of monclonal antibodies against Strail: Measurement of Strail by Elisa.
Journal of Immunological Methods (JIM)
Academic article
-
Kulseng, Bård Eirik;
Vatten, Lars Johan;
Espevik, Terje.
(1999)
Soluble tumor necrosis factor receptors in sera from patients with insulin-dependent diabetes mellitus: relations to duration and complications of disease.
Acta Dermato-Venereologica
Academic article
-
Liabakk, Nina-Beate;
Waage, Anders;
Lien, Egil;
Stenvik, Jørgen;
Espevik, Terje.
(2001)
Cytokine bioassays.
Methods in Molecular Medicine
Academic article
-
Flo, Trude Helen;
Halaas, Øyvind;
Torp, Sverre Helge;
Ryan, Liv;
Lien, Egil;
Dybdahl, Brit;
Sundan, Anders;
Espevik, Terje.
(2001)
Differential expression of Toll-like receptor 2 in human cells.
Journal of Leukocyte Biology
Academic article
-
Malmo, Jostein;
Moe, Nina;
Krokstad, Sidsel;
Ryan, Liv;
Loevenich, Simon;
Johnsen, Ingvild Bjellmo;
Espevik, Terje;
Nordbø, Svein Arne;
Døllner, Henrik;
Anthonsen, Marit Walbye.
(2016)
Cytokine profiles in human metapneumovirus infected children: Identification of genes involved in the antiviral response and pathogenesis.
PLOS ONE
Academic article
-
Latz, E;
Visintin, A;
Espevik, Terje;
Golenbock, DT.
(2004)
Mechanisms of TLR9 activation.
Journal of Endotoxin Research
Academic article
-
Heggelund, L;
Damås, Jan Kristian;
Damas, JK;
Yndestad, A;
Holm, AM;
Muller, F;
Lien, E;
Lien, E;
Espevik, Terje;
Aukrust, P.
(2004)
Stimulation of toll-like receptor 2 in mononuclear cells from HIV-infected patients induces chemokine responses: possible pathogenic consequences.
Clinical and Experimental Immunology
Academic article
-
Liabakk, Nina-Beate;
Espevik, Terje.
(2004)
Monoclonal antibodies against TRAIL.
Vitamines and Hormones
Academic article
-
Latz, E;
Schoenemeyer, A;
Visintin, A;
Fitzgerald, KA;
Monks, BG;
Knetter, Cathrine;
Lien, E;
Nilsen, Nadra;
Espevik, Terje;
Golenbock, DT.
(2004)
TLR9 signals after translocating from the ER to CpG DNA in the lysosome.
Nature Immunology
Academic article
-
Flo, Trude Helen;
Ryan, Liv;
Kilaas, L;
Skjåk-Bræk, Gudmund;
Ingalls, Robin;
Sundan, Anders;
Golenbock, D;
Espevik, Terje.
(2001)
The involvement of CD14 and beta2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers.
Infection and Immunity
Academic article
-
Skjermo, Jorunn;
Defoort, Thomas;
Dehasque, Marleen;
Espevik, Terje;
Olsen, Yngvar;
Skjåk-Bræk, Gudmund;
Sorgeloost, Patrick;
Vadstein, Olav.
(1995)
Immunostimulation of juvenile turbot (Scophthalmus maximus L.) using an alginate with high mannuronic acid content administered via the live food organism Artemia.
Fish and Shellfish Immunology
Academic article
-
Ehrnstrøm, Birgitta;
Kojen, June Frengen;
Giambelluca, Miriam;
Ryan, Liv;
Moen, Siv Helen;
Hu, Zhenyi;
Yin, Hang;
Mollnes, Tom Eirik;
Damås, Jan Kristian;
Espevik, Terje.
(2020)
TLR8 and complement C5 induce cytokine release and thrombin activation in human whole blood challenged with Gram-positive bacteria.
Journal of Leukocyte Biology
Academic article
-
Christensen, Jacob J.;
Bakke, Siril Skaret;
Ulven, Stine Marie;
Retterstøl, Kjetil;
Henriksen, Tore;
Bollerslev, Jens;
Espevik, Terje;
Aukrust, Pål;
Halvorsen, Bente;
Holven, Kirsten Bjørklund.
(2019)
Serum Omega-6 Fatty Acids and Immunology-Related Gene Expression in Peripheral Blood Mononuclear Cells: A Cross-Sectional Analysis in Healthy Children.
Molecular Nutrition & Food Research
Academic article
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Olsen, Maria Belland;
Kong, Xiang Yi;
Louwe, Maria;
Lauritzen, Knut Husø;
Schanke, Ylva;
Kaasbøll, Ole Jørgen;
Attramadal, Håvard;
Øgaard, Jonas Daniel Sjøberg;
Holm, Sverre;
Aukrust, Pål.
(2024)
SLAMF1-derived peptide exhibits cardio protection after permanent left anterior descending artery ligation in mice.
Frontiers in Immunology
Academic article
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Egge, Kjetil Hagene;
Barratt-Due, Andreas;
Nymo, Stig Haugset;
Lindstad, Julie Katrine;
Pharo, Anne Margrethe;
Lau, Corinna;
Espevik, Terje;
Thorgersen, Ebbe Billmann;
Mollnes, Tom Eirik.
(2015)
The anti-inflammatory effect of combined complement and CD14 inhibition is preserved during escalating bacterial load.
Clinical and Experimental Immunology
Academic article
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Thu, Beate;
Bruheim, Per;
Espevik, Terje;
Smidsrød, Olav;
Soon-Shiong, Patrick;
Skjåk-Bræk, Gudmund.
(1996)
Alginate polycation microcapsules. II, Some functional properties.
Biomaterials
Academic article
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Samuelsen, Anne Berit;
Paulsen, Berit Smestad;
Wold, Jens Krisitian;
Otsuka, Hanako;
Yamada, Haruki;
Espevik, T.
(1995)
Isolation and partial characterization of biologically active polysaccharides from Plantago major L.
Phytotherapy Research
Academic article
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Nymo, Stig Haugset;
Gustavsen, Alice;
Nilsson, Per;
Lau, Corinna;
Espevik, Terje;
Mollnes, Tom Eirik.
(2016)
Human endothelial cell activation by Escherichia coli and staphylococcus aureus is mediated by TNF and IL-1β secondarily to activation of C5 and CD14 in whole blood.
Journal of Immunology
Academic article
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Tunheim, G;
Thompson, KM;
Fredriksen, AB;
Espevik, Terje;
Schjetne, KW;
Bogen, B.
(2007)
Human receptors of innate immunity (CD14, TLR2) are promising targets for novel recombinant immunoglobulin-based vaccine candidates.
Vaccine
Academic article
-
Hetland, Geir;
Tryggestad, Anne Merete Aaland;
Espevik, Terje;
Ryan, Liv;
Tangen, Jon-Magnus;
Johnson, Egil;
Kvalheim, Gunnar.
(2010)
The medicinal and antitumour mushroom, agaricus blazei murill, activates NF-KB via TLR2 in monocytic cells and induces expression of cell surface markers and production of cytokines in human monocyte-derived dendritic cells (MDDC) in vitro.
European Journal of Cancer
Conference abstract
-
Moen, Siv Helen;
Ehrnstrøm, Birgitta;
Kojen, June Frengen;
Yurchenko, Mariya;
Beckwith, Kai Sandvold;
Afset, Jan Egil;
Damås, Jan Kristian;
Hu, Zhenyi;
Yin, Hang;
Espevik, Terje.
(2019)
Human Toll-like receptor 8 (TLR8) is an important sensor of pyogenic bacteria, and is attenuated by cell surface TLR signaling.
Frontiers in Immunology
Academic article
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Sandor, F;
Latz, Eicke;
Mandell, L;
Repik, G;
Golenbock, Douglas T.;
Espevik, Terje;
Kurt-Jones, EA;
Finberg, RW.
(2003)
Importance of extra- and intracellular domains of TLR1 and TLR2 in NFkappa B signaling.
Journal of Cell Biology
Academic article
-
Espevik, Terje;
Latz, Eicke;
Lien, Egil;
Monks, Brian G..
(2003)
Cell distribution and functions of Toll-like receptor 4 studied by fluorescent gene constructs.
Scandinavian Journal of Infectious Diseases
Academic article
-
Heggelund, Lars;
Flo, T;
Berg, K;
Lien, T;
Mollnes, TE;
Ueland, Thor;
Aukrust, Pål;
Espevik, T;
Frøland, Stig Sophus.
(2004)
Soluble toll-like receptor 2 in HIV infection: association with disease progression.
AIDS (London)
Academic article
-
Brekke, OL;
Espevik, Terje;
Bjerve, Kristian S.
(1994)
Butylated Hydroxyanisole Inhibits Tumor Necrosis Factor induced Cytotoxicity and Arachidonic Acid Release.
Lipids
Academic article
-
Rokstad, Anne Mari;
Brekke, Ole Lars;
Steinkjer, Bjørg;
Ryan, Liv;
Kolláriková, Gabriela;
Lambris, John D.;
Lacík, Igor;
Mollnes, Tom Eirik;
Espevik, Terje.
(2012)
Poly-cation containing alginate microcapsules induce cytokines by a complement-dependent mechanism.
Immunobiology
Conference abstract
-
Brekke, OL;
Espevik, Terje;
Bardal, Tora;
Bjerve, Kristian S.
(1992)
Effects of n-3 and n-6 fatty acids on Tumor Necrosis Factor cytotoxicity in WEHI fibrosarcoma cells.
Lipids
Academic article
-
Brekke, OL;
Shalaby, MR;
Sundan, Anders;
Espevik, Terje;
Bjerve, Kristian S.
(1992)
Butylated hydroxyanisol specifically inhibits Tumor Necrosis Factor induced cytotoxicity and growth enhancement.
Cytokine
Academic article
-
Franklin, Bernardo S;
Bossaller, Lukas;
Nardo, Dominic De;
Ratter, Jacqueline M;
Stutz, Andrea;
Engels, Gudrun;
Brenker, Christoph;
Nordhoff, Mark;
Mirandola, Sandra R;
Al-Amoudi, Ashraf.
(2014)
The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation.
Nature Immunology
Academic article
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Castellheim, A;
Brekke, Ole Lars;
Espevik, T;
Harboe, M;
Harboe, M;
Mollnes, Tom Eirik.
(2009)
Innate Immune Responses to Danger Signals in Systemic Inflammatory Response Syndrome and Sepsis.
Scandinavian Journal of Immunology
Academic literature review
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Bohnhorst, Janne Øvrebø;
Rasmussen, T;
Moen, Siv H;
Fløttum, Marianne;
Knudsen, L;
Børset, Magne;
Espevik, Terje;
Sundan, Anders.
(2006)
Toll-like receptors mediate proliferation and survival of multiple myeloma cells.
Leukemia
Academic article
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Sandler, Stellan;
Andersson, Arne;
Eizirik, Décio L.;
Hellerström, Claes;
Espevik, Terje;
Kulseng, Siri;
Thu, Beate;
Pipeleers, Daniel G.;
Skjåk-Bræk, Gudmund.
(1997)
Assessment of insulin secretion in vitro from microencapsulated fetal procine islet-like cell clusters and rat, mouse, and human pancreatic islets.
Transplantation
Academic article
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Kulseng, Bård Eirik;
Thu, Beate;
Espevik, Terje;
Skjåk-Bræk, Gudmund.
(1997)
Alginate polylysine microcapsules as immune barrer : permeability of cytokines and immmunoglobulins over the capsule membrane.
Cell Transplantation
Academic article
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Lau, Corinna;
Nygård, Ståle;
Fure, Hilde;
Olstad, Ole Kristoffer;
Holden, Marit;
Lappegård, Knut Tore;
Brekke, Ole Lars;
Espevik, Terje;
Hovig, Johannes Eivind;
Mollnes, Tom Eirik.
(2015)
CD14 and complement crosstalk and largely mediate the transcriptional response to Escherichia coli in human whole blood as revealed by DNA microarray.
PLOS ONE
Academic article
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Gregersen, Ida;
Ueland, Thor;
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Legumain is upregulated in acute cardiovascular events and associated with improved outcome – potentially related to anti-inflammatory effects on macrophages.
Atherosclerosis
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European Journal of Cardio-Thoracic Surgery
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Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction.
Journal of Biological Chemistry
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Cutting edge: link between innate and adaptive immunity: Toll-like receptor 2 internalizes antigen for presentation to CD4+ T cells and could be an efficient vaccine target.
Journal of Immunology
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Surface Toll-Like Receptor 3 Expression in Metastatic Intestinal Epithelial Cells induces Selective Cytokine Production and Promotes Invasiveness.
Journal of Biological Chemistry
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Bösl, Korbinian;
Gravastrand, Caroline S.;
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PLoS Pathogens
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Academic article
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Intracellular Mycobacterium avium Intersect Transferrin in the Rab11(+) Recycling Endocytic Pathway and Avoid Lipocalin 2 Trafficking to the Lysosomal Pathway.
Journal of Infectious Diseases
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Phagocytosis of Escherichia coli in human whole blood: Early complement dependency is succeeded by late CD14 dependency over time.
Immunobiology
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Fageräng, Beatrice Linnea Christina;
Cyranka, Leon;
Schjalm, Camilla;
Ekholt, Karin;
Larsen, Carina Sandem;
Heinzelbecker, Julia;
Gedde-Dahl, Tobias;
Würzner, Reinhard;
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Tjønnfjord, Geir Erland.
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The function of the complement system remains fully intact throughout the course of allogeneic stem cell transplantation.
Frontiers in Immunology
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Elevated levels of serum-soluble CD14 in human immonudeficiency virus type 1 (HIV-1) infection: correlation to disease progression and clinical events.
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Combined Inhibition of C5 and CD14 Attenuates Systemic Inflammation in a Piglet Model of Meconium Aspiration Syndrome.
Neonatology
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Soluble urinary CD14 after intravesical bacille Calmette-Guérin immunotherapy for carcinoma in situ.
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TIRAP/Mal Positively Regulates TLR8‐Mediated Signaling via IRF5 in Human Cells.
Biomedicines
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Steinkjer, Bjørg;
Nilsen, Nadra;
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SLA MF1 is required for TLR4-mediated TRAM-TRIF- dependent signaling in human macrophages.
Journal of Cell Biology
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CD14, TLR4 and TRAM Show Different Trafficking Dynamics During LPS Stimulation.
Traffic: The moving front of cell biology
Academic article
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Apoptosis, proliferation and NF-k(kappa)B activation induced by agonistic Fas antibodies in the human myeloma cell line OH-2: amplification of Fas-mediated apoptosis by tumor necrosis factor.
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Granlund, Atle Van Beelen;
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Induction of Lipocalin-2 in Colonic Epithelial Cells in Inflammatory Bowel Disease.
Inflammatory Bowel Diseases
Conference abstract
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Niyonzima, Nathalie;
Samstad, Eivind;
Aune, Marie Hjelmseth;
Ryan, Liv;
Bakke, Siril Skaret;
Rokstad, Anne Mari;
Wright, Samuel;
Damås, Jan Kristian;
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Latz, Eicke.
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Reconstituted high-density lipoprotein attenuates cholesterol crystal-induced inflammatory responses by reducing complement activation.
Journal of Immunology
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Strand, Berit Løkensgard;
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Kulseng, Bård Eirik;
Skjåk-Bræk, Gudmund;
Espevik, Terje.
(2003)
Evaluation of different types of alginate microcapsules as bioreactors for producing endostatin.
Cell Transplantation
Academic article
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Aukrust, Pål;
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Ueland, Thor;
Lien, Egil;
Müller, Fredrik;
Espevik, Terje;
Bollerslev, Jens;
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Decreased bone formative and enhanced resorptive markers in human immunodeficiency virus infection: Indication of normalization of the bone-remodeling process during highly active antiretroviral therapy.
Journal of Clinical Endocrinology and Metabolism (JCEM)
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Aukrust, Pål;
Müller, Fredrik;
Lien, Egil;
Nordøy, Ingvild;
Liabakk, Nina-Beate;
Kvale, Dag;
Espevik, Terje;
Frøland, Stig S..
(1999)
Tumor necrosis factor (TNF) system levels in human immunodificiency virus-infected patients during highly active antiretroviral therapy: Perisistent TNF activation is associated with virologic and immunologic treatment failure.
Journal of Infectious Diseases
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Dual inhibition of complement and Toll-like receptors as a novel approach to treat inflammatory diseases-C3 or C5 emerge together with CD14 as promising targets.
Journal of Leukocyte Biology
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Espevik, T;
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Does Toll-like Receptor 9 Signaling Play a Role in Myeloma Disease Progression?.
Clinical Lymphoma & Myeloma
Conference abstract
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Hellerud, BC;
Stenvik, Jørgen;
Espevik, Terje;
Lambris, John D.;
Mollnes, Tom Eirik;
Brandtzaeg, P.
(2008)
Stages of meningococcal sepsis stimulated in vitro, with emphasis on complement and Toll-like receptor activation.
Infection and Immunity
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Hammerstrøm, J;
Espevik, Terje;
Nissen-Meyer, J.
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Human monocyte cytotoxic factor mediates cytolysis of WEHI 164 cells.
Cellular Immunology
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Benzyl-para-di-[5-methyl-4-(n-octylamino) pyrimidin-2(1H)one] as an interferon beta (IFN-β) modulator.
Molecular diversity
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Monocyte-mediated drug-dependent cellular cytotoxicity: Effects of different WEHI 164 target cell lines.
Cancer Immunology and Immunotherapy
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Interleukin-6 receptor inhibition with tocilizumab induces a selective and substantial increase in plasma IP-10 and MIP-1β in non-ST-elevation myocardial infarction.
International Journal of Cardiology
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Higher order structure of short immunostimulatory oligonucleotides studied by atomic force microscopy.
Ultramicroscopy
Academic article
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Nilsen, Nadra;
Granlund, Atle;
Torp, Sverre Helge;
Flatberg, Arnar;
Waldum, Helge;
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Enhanced expression of CXCL10 in inflammatory bowel disease-role of mucosal TLR3 stimulation.
Journal of Crohn’s and Coltis Supplements
Conference abstract
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Nymo, Stig Haugset;
Samstad, Eivind;
Niyonzima, Nathalie;
Aune, Marie Hjelmseth;
Bergseth, Grete;
Ryan, Liv;
Brekke, Ole Lars;
Latz, E;
Lambris, J.D.;
Espevik, Terje.
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Cholesterol crystals activate the complement system and are phagocytosed in a complement-dependent manner.
Molecular Immunology
Conference abstract
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Lau, Corinna;
Olstad, Ole Kristoffer;
Holden, Marit;
Nygård, Ståle;
Fure, Hilde;
Lappegård, Knut Tore;
Brekke, Ole Lars;
Espevik, Terje;
Hovig, Johannes Eivind;
Mollnes, Tom Eirik.
(2015)
Gene expression profiling of Gram-negative bacteria-induced inflammation in human whole blood: The role of complement and CD14-mediated innate immune response.
Genomics Data
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Niyonzima, Nathalie;
Halvorsen, Bente;
Sporsheim, Bjørnar;
Garred, Peter;
Aukrust, Pål;
Mollnes, Tom Eirik;
Espevik, Terje.
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Complement activation by cholesterol crystals triggers a subsequent cytokine response.
Molecular Immunology
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Doyle, SL;
McGettrick, AF;
Hardy, M;
Husebye, Harald;
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Gong, M;
Golenbock, D;
Espevik, Terje;
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TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway.
Nature Immunology
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Cavanagh, Jorunn Pauline;
Høiland, Ina Isabella;
Ludviksen, Judith K;
Lau, Corinna;
Espevik, Terje;
Mollnes, Tom Eirik;
Klingenberg, Claus Andreas.
(2023)
Dual inhibition of complement C5 and CD14 attenuates inflammation in a cord blood model.
Pediatric Research
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Comparison of recombinant tumor necrosis factor and the monocyte-derived cytotoxic factor (CF) which is involved in the monocyte-mediated cytotoxicity.
Cancer Research
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Espevik, Terje;
Skjåk-Bræk, Gudmund.
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Cell-compatible covalently reinforced beads obtained from a chemoenzymatically engineered alginate.
Biomaterials
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Nissen-Meyer, J.
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Fibroblast growth stimulatory activity from human monocytes: The contribution of tumor necrosis factor.
Scandinavian Journal of Immunology
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Monocyte-derived influence on growth of normal human fibroblasts: The contribution of tumor necrosis factor to growth inhibition.
Scandinavian Journal of Immunology
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Nymo, Stig Haugset;
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Brekke, Ole Lars;
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Aukrust, Pål;
Damås, Jan Kristian;
Latz, Eicke.
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Cholesterol crystals induce inflammasome activation and cytolcine release in a complement-dependent manner.
Molecular Immunology
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Austgulen, Rigmor;
Espevik, Terje;
Hammerstrøm, J;
Nissen-Meyer, J.
(1986)
Role of monocyte cytotoxic factor in cytolysis of actinomycin D treated WEHI 164 cells mediated by freshly isolated human adherent mononuclear blood cells.
Cancer Research
Academic article
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Strand, Berit Løkensgard;
Skjåk-Bræk, Gudmund;
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Transplantation of alginate microcapsules with proliferating cells in mice. Capsular overgrowth and suvival of encapsulated cells of mice and human origin.
Annals of the New York Academy of Sciences
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Gene expression and secretion of cytokines and cytokine receptors from hihgly purified CD56+ natural killer cells stimulated with interleukin-2, interleukin-7 and interleukin-12.
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Garred, Peter;
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Aukrust, Pål;
Yndestad, Arne;
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Hovland, Anders.
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A vital role for complement in heart disease.
Molecular Immunology
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Rahman, Jubayer;
Kunz, Natalie;
West, Erin;
Freiwald, Tilo;
Desai, Jigar V.;
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Gidon, Alexandre;
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Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation.
Science immunology
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Regulation of Fas and Fas-Ligand expression in NK cells by cytokines and the involvement of Fas-Ligand in NK/LAK cell-mediated cytotoxicity.
Cytokine
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Polymorphonuclear granulocytes enhance lipopolysaccharide-induced p75 tumor necrosis factor receptor release from mononuclear cells.
European Journal of Immunology
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Takeuchi, Osamu;
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Halaas, Øyvind;
Akira, Shizuo;
Skjåk-Bræk, Gudmund;
Golenbock, Douglas T..
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Involvement of toll-like receptor (TLR) 2 and TLR4 in cell activation by mannuronic acid polymers.
Journal of Biological Chemistry
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Rokstad, Anne Mari Aukan;
Holtan, Synnøve;
Strand, Berit Løkensgard;
Steinkjer, Bjørg;
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Kulseng, Bård Eirik;
Skjåk-Bræk, Gudmund;
Espevik, Terje.
(2002)
Microencapsulation of cells producing therapeutic proteins: Optimizing cell growth and secretion.
Cell Transplantation
Academic article
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Hovland, Anders;
Jonasson, Lena;
Garred, Peter;
Yndestad, Arne;
Aukrust, Pål;
Lappegård, Knut Tore;
Espevik, Terje;
Mollnes, Tom Eirik.
(2015)
The complement system and toll-like receptors as integrated players in the pathophysiology of atherosclerosis.
Atherosclerosis
Academic literature review
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Kulseng, Bård Eirik;
Skjåk-Bræk, Gudmund;
Ryan, Liv;
Andersson, Arne;
King, Aileen;
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Espevik, Terje.
(1999)
Transplantation of alginate microcapsules.
Transplantation
Academic article
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Iversen, Ann-Charlotte;
Johnsen, Ann-Charlotte;
Haux, Johan;
Steinkjer, Bjørg;
Nonstad, Unni;
Egeberg, Kjartan Wøllo;
Sundan, Anders;
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(1999)
Regulation of Apo-2 Ligand/Trail expression in NK cells - Involvement in NK cell mediated cytotoxicity.
Cytokine
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Haux, Johan;
Iversen, Ann-Charlotte;
Johnsen, Ann-Charlotte;
Steinkjer, Bjørg;
Egeberg, Kjartan Wøllo;
Sundan, Anders;
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(1999)
The role of IL-2 in regulating the sensitivity of NK cells for Fas-mediated apoptosis.
Cancer Immunology and Immunotherapy
Academic article
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Huber-Lang, Markus;
Barratt-Due, Andreas;
Pischke, Søren Erik;
Sandanger, Øystein;
Nilsson, Per;
Nunn, Miles A.;
Denk, Stephanie;
Gaus, Wilhelm;
Espevik, Terje;
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Double blockade of CD14 and complement C5 abolishes the cytokine storm and improves morbidity and survival in polymicrobial sepsis in mice.
Journal of Immunology
Academic article
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Nymo, Stig;
Samstad, Eivind;
Niyonzima, Nathalie;
Bergseth, Grethe;
Christiansen, Dorte;
Ryan, Liv;
Brekke, Ole Lars;
Lappegard, Knut Tore;
Damas, Jan Kristian;
Latz, Eicke.
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Complement dependency of cholesterol crystal-induced inflammation - I. Pathway activation mechanisms, cytokine responses and endothelial cell activation.
Immunobiology
Conference abstract
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Narverud, Ingunn;
Christensen, Jacob J.;
Bakke, Siril Skaret;
Ulven, Stine Marie;
Rundblad, Amanda;
Aukrust, Pål;
Espevik, Terje;
Bogsrud, Martin Prøven;
Retterstøl, Kjetil;
Ueland, Thor.
(2019)
Profiling of immune-related gene expression in children with familial hypercholesterolaemia.
Journal of Internal Medicine
Academic article
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Rokstad, Anne Mari;
Brekke, Ole Lars;
Steinkjer, Bjørg;
Ryan, Liv;
Kolláriková, Gabriela;
Strand, Berit Løkensgard;
Skjåk-Bræk, Gudmund;
Lacík, Igor;
Espevik, Terje;
Mollnes, Tom Eirik.
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Alginate microbeads are complement compatible, in contrast to polycation containing microcapsules, as revealed in a human whole blood model.
Acta Biomaterialia
Academic article
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Skjeflo, Espen;
Christiansen, Dorte;
Lambris, John D.;
Espevik, Terje;
Nielsen, Erik Waage;
Mollnes, Tom Eirik.
(2012)
Combined inhibition of complement and CD14 efficiently attenuated the inflammatory response induced by Staphylococcus aureus in a human whole blood model.
Immunobiology
Conference abstract
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Rokstad, Anne Mari;
Gustafsson, Björn;
Espevik, Terje;
Bakke, Ingunn;
Pfragner, Roswitha;
Svejda, Bernhard;
Modlin, Irvin M;
Kidd, Mark.
(2012)
Microencapsulation of small intestinal neuroendocrine neoplasm cells for tumor model studies.
Cancer Science
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Varghese, Paramel G;
Folkersen, Lasse;
Strawbridge, Rona J.;
Halvorsen, Bente;
Yndestad, Arne;
Ranheim, Trine;
Krogh-Sørensen, Kristin;
Skjelland, Mona;
Espevik, Terje;
Aukrust, Pål.
(2016)
NLRP3 inflammasome expression and activation in human atherosclerosis.
Journal of the American Heart Association (JAHA)
Academic article
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Skjeflo, Espen Waage;
Christiansen, Dorte;
Fure, Hilde;
Ludviksen, Judith K;
Woodruff, Trent M.;
Espevik, Terje;
Nielsen, Erik Waage;
Brekke, Ole-Lars;
Mollnes, Tom Eirik.
(2018)
Staphylococcus aureus-induced complement activation promotes tissue factor-mediated coagulation.
Journal of Thrombosis and Haemostasis
Academic article
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Skjeflo, Espen Waage;
Christiansen, Dorte;
Landsem, Anne;
Stenvik, Jørgen;
Woodruff, T. M.;
Espevik, Terje;
Nielsen, Erik Waage;
Mollnes, Tom Eirik.
(2019)
Phagocytosis of live and dead Escherichia coli and Staphylococcus aureus in human whole blood is markedly reduced by combined inhibition of C5aR1 and CD14.
Molecular Immunology
Academic article
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Sponaas, Anne-Marit;
Moen, Siv Helen;
Liabakk, Nina-Beate;
Feyzi, Emadoldin;
Holien, Toril;
Kvam, Solveig;
Grøseth, Lill Anny Gunnes;
Størdal, Berit Fladvad;
Buene, Glenn;
Espevik, Terje.
(2015)
The proportion of CD16+CD14dim monocytes increases with tumor cell load in bone marrow of patients with multiple myeloma.
Immunity,Inflammation and Disease
Academic article
-
Strand, Berit Løkensgard;
Ryan, Liv;
Veld, Peter Int;
Kulseng, Bård Eirik;
Rokstad, Anne Mari Aukan;
Skjåk-Bræk, Gudmund;
Espevik, Terje.
(2001)
Poly-L-Lysine Induces Fibrosis on Alginate Microcapsules via the Induction of Cytokines.
Cell Transplantation
Academic article
-
Niyonzima, Nathalie;
Samstad, Eivind;
Aune, Marie Hjelmseth;
Ryan, Liv;
Damås, Jan Kristian;
Wright, Samuel;
Sandanger, Øystein;
Aukrust, Pål;
Latz, Eicke;
Mollnes, Tom Eirik.
(2012)
Complement dependency of cholesterol crystal-induced inflammation - II. Inflammasome activation and regulation mechanisms involving reconstituted high density lipoprotein (HDL) and C-reactive protein (CRP).
Immunobiology
Conference abstract
-
Zhang, Boyao;
Ørning, Mathias Pontus;
Lehman, Jesse W.;
Dinis, Alexandre;
Torres-Ulloa, Leslie;
Elling, Roland;
Kelliher, Michelle A.;
Bertin, John;
Proulx, Megan K.;
Goguen, Jon D..
(2025)
Raver1 links Ripk1 RNA splicing to caspase-8-mediated pyroptotic cell death, inflammation, and pathogen resistance.
Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Academic article
-
Aukrust, Pål;
Hestdal, Ketil;
Lien, Egil;
Bjerkeli, Vigdis;
Nordøy, Ingvild;
Espevik, Terje;
Myller, Stig;
Frøland, S..
(1997)
Effects of intravenous immunoglobulin in vivo on abnormally increased tumor necrosis factor-alpha activity in human immunodeficiency virus type 1 infection.
Journal of Infectious Diseases
Academic article
-
Sandanger, Øystein;
Sandanger, O;
Ryan, Liv;
Bohnhorst, Janne Øvrebø;
Iversen, Ann-Charlotte;
Iversen, AC;
Husebye, Harald;
Halaas, Øyvind;
Halaas, O;
Landrø, Linn.
(2009)
IL-10 Enhances MD-2 and CD14 Expression in Monocytes and the Proteins Are Increased and Correlated in HIV-Infected Patients.
Journal of Immunology
Academic article
-
Espada Serrano, Sandra;
Stavik, Benedicte;
Holm, Sverre;
Sagen, Ellen Lund;
Bjerkeli, Vigdis;
Skjelland, Mona;
Dahl, Tuva Børresdatter;
Espevik, Terje;
Kanse, Sandip;
Sandset, Per Morten.
(2017)
Tissue factor pathway inhibitor attenuates ER stress-induced inflammation in human M2-polarized macrophages.
Biochemical and Biophysical Research Communications - BBRC
Academic article
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Ingalls, RR;
Monks, BG;
R, [Mangler fornavn] Savedra;
Christ, WJ;
Delude, RL;
Medvedev, AE;
Espevik, Terje;
Golenbock, DT.
(1998)
CD11/CD18 and CD14 share a common lipid A signaling pathway.
Journal of Immunology
Academic article
-
Thommesen, Liv;
Sjursen, Wenche;
Gåsvik, Kathrine;
Hanssen, Wenche;
Brekke, Ole-Lars;
Skattebøl, Lars;
Holmeide, Anne Kristin;
Espevik, Terje;
Johansen, Berit;
Lægreid, Astrid.
(1998)
Selective inhibitors of cytosolic or secretory phospholipase A2 block TNF-induced activation of transcription factor nuclear factor-kappa B and expression of ICAM-1.
Journal of Immunology
Academic article
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Bergstrøm, Bjarte;
Aune, Marie Hjelmseth;
Awuh, Jane Atesoh;
Kojen, June Frengen;
Blix, Kjetil Jordahl;
Ryan, Liv;
Flo, Trude Helen;
Mollnes, Tom Eirik;
Espevik, Terje;
Stenvik, Jørgen.
(2015)
TLR8 senses Staphylococcus aureus RNA in human primary monocytes and macrophages and induces IFN-β production via a TAK1-IKKβ-IRF5 signaling pathway.
Journal of Immunology
Academic article
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Soon-Shong, P.;
Feldman, E.;
Nelson, R.;
Komtebedde, J.;
Smidsrød, Olav;
Skjåk-Bræk, Gudmund;
Espevik, Terje;
Heintz, R.;
Lee, M..
(1992)
Successful reversal of spontaneous diabetes in dogs by intraperitonal microencapsulated islets.
Transplantation
Academic article
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Hetland, Geir;
Tryggestad, Anne Merete Aaland;
Espevik, Terje;
Ryan, Liv.
(2013)
The medicinal mushroom Agaricus blazei Murill promotes NF-B activation via stimulation of TLR2 and inhibits its activation via TLR4.
Journal of Pharmaceutical and Biomedical Sciences
Academic article
-
Medvedev, AE;
Flo, T;
Vogel, SN;
Robin, R;
Golenbock, DT;
Teti, G;
Espevik, Terje.
(1998)
Involvement of CD14 and complement receptors CR3 and CR4 in nuclear factor-kappaB activation and TNF production induced by lipopolysaccharide and group B streptococcal cell walls.
Journal of Immunology
Academic article
-
Cuzzola, M.;
Mancuso, G.;
Beninati, C.;
Biondo, C.;
Genovese, F.;
Tomasello, F.;
Flo, Trude Helen;
Espevik, Terje;
Teti, G..
(2000)
_B2 integrins are involved in cytokine responses to whole gram-positive bacteria.
Journal of Immunology
Academic article
-
Espevik, Terje;
Skjåk-Bræk, Gudmund.
(2006)
Friskere fisk med tang og tare.
Gemini
Popular science article
-
Halaas, Øyvind;
Vik, R;
Espevik, Terje.
(1998)
Induction of Fas ligand in murine bone marrow NK cells by bacterial polysaccharides.
Immunology
Academic article
-
Gravastrand, Caroline;
Hamad, Shamal;
Fure, Hilde;
Steinkjer, Bjørg;
Ryan, Liv;
Oberholzer, José;
Lambris, John D.;
Lacík, Igor;
Mollnes, Tom Eirik;
Espevik, Terje.
(2017)
Alginate microbeads are coagulation compatible, while alginate
microcapsules activate coagulation secondary to complement or
directly through FXII.
Acta Biomaterialia
Academic article
-
Salvesen, Bodil;
Stenvik, Jørgen;
Rosetti, Carlo;
Saugstad, Ola D;
Espevik, Terje;
Mollnes, Tom E..
(2010)
Meconium-induced release of cytokines is mediated by the TRL4/MD-2 complex in a CD14-dependent manner.
Molecular Immunology
Academic article
-
Duewell, P;
Kono, H;
Rayner, KJ;
Sirois, CM;
Vladimer, G;
Bauernfeind, FG;
Abela, GS;
Franchi, L;
Nunez, G;
Schnurr, M.
(2010)
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
Nature
Academic article
-
Etokebe, GE;
Skjeldal, F;
Nilsen, Nadra;
Rodionov, Dmitrii;
Knezevic, Jelena;
Bulat-Kardum, Ljiljana;
Espevik, Terje;
Bakke, Oddmund;
Dembic, Zlatko.
(2010)
Toll-Like Receptor 2 (P631H) Mutant Impairs Membrane Internalization and is a Dominant Negative Allele.
Scandinavian Journal of Immunology
Academic article
-
Hestdal, Kjetil;
Aukrust, Pål;
Müller, Fredrik;
Lien, Egil;
Bjerkeli, Vigdis;
Espevik, Terje;
Frøland, Stig S..
(1997)
Dysregulation of membrane-bound tumor necrosis factor-_a and tumor necrosis factor receptors on mononuclear cells in human immunodeficiency virus type 1 infection : low percentage of p75-tumor necrosis factor receptor positive cells in patients with advanced disease and high viral load.
Blood
Academic article
-
Pinto, Sneha M.;
Subbannayya, Yashwanth;
Kim, Hera;
Hagen, Lars;
Górna, Maria W;
Nieminen, Anni I.;
Bjørås, Magnar;
Espevik, Terje;
Kaynov, Denis;
Kandasamy, Richard Kumaran.
(2022)
Multi-OMICs landscape of SARS-CoV-2-induced host responses in human lung epithelial cells.
iScience
Academic article
-
Torgersen, Maria Lyngaas;
Engedal, Kim Nikolai;
Pedersen, Anne-Mari Gjestvang;
Husebye, Harald;
Espevik, Terje;
Sandvig, Kirsten.
(2011)
Toll-like receptor 4 facilitates binding of Shiga toxin to colon carcinoma and primary umbilical vein endothelial cells.
FEMS Immunology and Medical Microbiology
Academic article
-
Samstad, Eivind;
Niyonzima, Nathalie;
Nymo, Stig Haugset;
Aune, Marie Hjelmseth;
Ryan, Liv;
Bakke, Siril Skaret;
Lappegård, Knut Tore;
Brekke, Ole Lars;
Lambris, John D.;
Damås, Jan Kristian.
(2014)
Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release.
Journal of Immunology
Academic article
-
Aukrust, Pål;
Lien, Egil;
Kristoffersen, Anne Karin;
Muller, Fredrik;
Haug, Charlotte J.;
Espevik, T;
Frøland, Stig Sophus.
(1996)
Persistent activation of tumor necrosis factor system in a subgroup of patients with common variable immunodeficiency - Possible immunologic and clinical concensus.
Blood
Academic article
-
Espevik, Terje;
Lien, Egil.
(2006)
Vaksine mot svartedauen.
Gemini
Popular science article
-
Frantisek, S;
Latz, E;
Re, F;
Mandell, L;
Repik, G;
Golenbock, D;
Espevik, Terje;
Kurt-Jones, E;
Finberg, R.
(2004)
Importance of extra-and intracellular domains of TLR1 and TLR2 receptors in NF-kappa B signaling.
Tissue Antigens
Conference abstract
-
Flo, Trude Helen;
Ryan, Liv;
Kilaas, Lars;
Skjåk-Bræk, Gudmund;
Ingalls, Robin R.A;
Sundan, Anders;
Golenbock, Douglas T.;
Espevik, Terje.
(2000)
Involvement of CD14 and _B2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers.
Infection and Immunity
Academic article
-
Cuzzola, Maria;
Mancuso, Guiseppe;
Beninati, Concetta;
Biondo, Carmelo;
Hunolstein, Christina von;
Orefici, Graziella;
Espevik, Terje;
Flo, Trude Helen;
Teti, Guisseppe.
(2000)
Human monocyte receptors involved in tumor necrosis factor responses to group B streptococcal products.
Infection and Immunity
Academic article
-
Hellerud, Bernt C;
Orrem, Hilde Lang;
Dybwik, Knut Gustav;
Pischke, Søren Erik;
Barratt-Due, Andreas;
Castellheim, Albert;
Fure, Hilde;
Bergseth, Grete;
Christiansen, Dorte;
Nunn, Miles A..
(2017)
Combined inhibition of C5 and CD14 efficiently attenuated the inflammatory response in a porcine model of meningococcal sepsis.
Journal of Intensive Care
Academic article
-
Stenvik, Jørgen;
Sletta, Håvard;
Grimstad, Øystein;
Pukstad, Brita;
Ryan, Liv;
Aune, Randi;
Strand, Wenche Iren;
Tøndervik, Anne;
Torp, Sverre Helge;
Skjåk-Bræk, Gudmund.
(2012)
Alginates induce differentiation and expression of CXCR7 and CXCL12/SDF-1 in human keratinocytes - the role of calcium.
Journal of Biomedical Materials Research. Part A
Academic article
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Bösl, Korbinian;
Giambelluca, Miriam;
Haug, Markus;
Bugge, Marit;
Espevik, Terje;
Kandasamy, Richard Kumaran;
Bergstrøm, Bjarte Aune.
(2018)
Coactivation of TLR2 and TLR8 in primary human monocytes triggers a distinct inflammatory signaling response.
Frontiers in Physiology
Academic article
-
Kulseng, Bård Eirik;
Skjåk-Bræk, Gudmund;
Ryan, Liv;
Andersson, Arne;
King, Aileen;
Faxvaag, Arild;
Espevik, Terje.
(1999)
Transplantation of alginate microcapsules. Generation of antibodies against alginates and encapsulated porcine islet-like cell clusters.
Transplantation
Academic article
-
Heine, Holger;
Delude, Russell L.;
Monks, Biran G.;
Espevik, Terje;
Golenbock, Douglas T..
(1999)
Bacterial lipopolysaccharide induces expression of the stress response genes Hop and H411.
Journal of Biological Chemistry
Academic article
-
Bakke, Siril Skaret;
Aune, Marie Hjelmseth;
Niyonzima, Nathalie;
Pilely, Katrine;
Ryan, Liv;
Skjelland, Mona;
Garred, Peter;
Aukrust, Pål;
Halvorsen, Bente;
Latz, Eicke.
(2017)
Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation.
Journal of Immunology
Academic article
-
Skjeflo, Espen Waage;
Christiansen, Dorte;
Espevik, Terje;
Nielsen, Erik Waage;
Mollnes, Tom Eirik.
(2014)
Combined inhibition of complement and CD14 efficiently attenuated the inflammatory response induced by staphylococcus aureus in a human whole blood model.
Journal of Immunology
Academic article
-
Niyonzima, Nathalie;
Bakke, Siril Skaret;
Gregersen, Ida;
Holm, Sverre;
Sandanger, Øystein;
Orrem, Hilde Lang;
Sporsheim, Bjørnar;
Ryan, Liv;
Kong, Xiang Yi;
Dahl, Tuva Børresdatter.
(2020)
Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis.
EBioMedicine
Academic article
-
Haug, Charlotte J.;
Aukrust, Pål;
Lien, Egil;
Müller, Fredrik;
Espevik, Terje;
Frøland, Stig S..
(1996)
Disseminated Mycobacterium avium complex infection in AIDS : immunopathogenic significance of an activated tumor necrosis factor system and depressed serum levels of 1,25 dihydroxyvitamin D.
Journal of Infectious Diseases
Academic article
-
Østvik, Ann Elisabet;
Granlund, Atle;
Bugge, Marit;
Nilsen, Nadra;
Torp, Sverre Helge;
Waldum, Helge;
Damås, Jan Kristian;
Espevik, Terje;
Sandvik, Arne Kristian.
(2013)
Enhanced expression of CXCL10 in inflammatory bowel disease: Potential role of mucosal toll-like 3 receptor stimulation.
Inflammatory Bowel Diseases
Academic article
-
Medvedev, Andrei E.;
Espevik, Terje;
Ranges, Gerald;
Sundan, Anders.
(1996)
Distinct roles of the two tumor necrosis factor (TNF) receptors in modulating TNF and lymphotoxin _a effects.
Journal of Biological Chemistry
Academic article
-
Barratt-Due, Andreas;
Pischke, Søren Erik;
Brekke, Ole Lars;
Thorgersen, Ebbe Billmann;
Nielsen, Erik Waage;
Espevik, Terje;
Huber-Lang, Markus;
Mollnes, Tom Eirik.
(2012)
Bride and groom in systemic inflammation - The bells ring for complement and Toll in cooperation.
Immunobiology
Academic literature review
-
Granlund, Atle;
Flatberg, Arnar;
Østvik, Ann Elisabet;
Drozdov, I;
Gustafsson, Björn;
Kidd, M;
Beisvag, Vidar;
Torp, Sverre Helge;
Waldum, Helge;
Martinsen, Tom Christian.
(2012)
Dissecting the IBD Transcriptome.
Inflammatory Bowel Diseases
Conference abstract
-
Husebye, Harald;
Halaas, Øyvind;
Stenmark, Harald;
Tunheim, G;
Sandanger, Øystein;
Bogen, B;
Brech, A;
Latz, Eicke;
Espevik, Terje.
(2006)
Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity.
EMBO Journal
Academic article
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Mestvedt, Ingvild Bergdal;
Menu, Eline;
Misund, Kristine;
Slørdahl, Tobias Schmidt;
Rasheed, Kashif;
Wolowczyk, Camilla Izabel;
Hella, Hanne;
Ryan, Liv;
Standal, Therese;
Espevik, Terje.
(2025)
Novel SLAMF1-derived peptide induces apoptosis in multiple myeloma cells by targeting IRF4 transcription factor for degradation.
BioRxiv
Academic article
-
Espevik, Terje.
(2017)
Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation.
Journal of Immunology
Academic article
-
Strand, Berit Løkensgard;
Gåserød, Olav;
Kulseng, Bård Eirik;
Espevik, Terje;
Skjåk-Bræk, Gudmund.
(2002)
Alginate-polylysine-alginate microcapsules – effect of size reduction on capsule properties.
Journal of Microencapsulation
Academic article
-
Ueland, Thor;
Espevik, Terje;
Kjekshus, John;
Gullestad, Lars;
Omland, Torbjørn;
Squire, Iain B.;
Frøland, Stig S.;
Froland, Stig S;
Mollnes, Tom Eirik;
dickstein, Kenneth.
(2006)
Mannose binding lectin and soluble Toll-lilke receptor 2 in heart failure following acute myocardial infarction.
Journal of Cardiac Failure
Academic article
-
Iversen, Ann-Charlotte;
Johnsen, Ann-Charlotte;
Haux, Johan;
Steinkjer, Bjørg;
Nonstad, Unni;
Egeberg, Kjartan Wøllo;
Ashkenazi, Avi;
Sundan, Anders;
Espevik, Terje.
(1998)
Regulation of Apo-2 Ligand/TRAIL expression in NK cells - Involvement in NK cell mediated cytotoxicity.
Journal of Interferon and Cytokine Research
Conference abstract
-
Mollnes, Tom Eirik;
Barratt-Due, Andreas;
Pischke, Søren Erik;
Sandanger, Inger;
Nilsson, Per;
Lambris, J;
Nunn, Miles A.;
Denk, Stephanie;
Espevik, Terje;
Huber-Lang, Markus.
(2013)
Double-blockade of CD14 and complement component C5 abolish the inflammatory storm and improve survival in mouse polymicrobial sepsis.
Molecular Immunology
Conference abstract
-
Lien, E;
Sundan, A;
Aukrust, P;
Frøland, S;
Espevik, Terje.
(1998)
Elevated levels of serum-soluble CD14 in human immunodeficiency virus type 1 (HIV-1) infection: correlation to disease progression and clinical events.
Blood
Academic article
-
Kulseng, Bård Eirik;
Espevik, Terje;
Sundan, A.
(1998)
Elevated hepatocyte growth factor in sera from patients with insulin-dependent diabetes mellitus.
Acta Dermato-Venereologica
Academic article
-
Medvedev, Andrei E.;
Lægreid, Astrid;
Sundan, Anders;
Espevik, Terje.
(1996)
A non-competitive P55 TNF receptor antibody enhances the specific activity of Lymphotoxin-_a.
Scandinavian Journal of Immunology
Academic article
-
Doyle, SL;
Husebye, Harald;
Connolly, D;
Espevik, Terje;
O'Neill, LAJ;
McGettrick, AF.
(2012)
The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation.
Nature Communications
Academic article
-
Heggelund, Lars;
Mollnes, Tom Eirik;
Espevik, Terje;
Muller, Fredrik;
Kristiansen, Knut Ivan;
Aukrust, Pål;
Frøland, Stig Sophus.
(2005)
Modulatory effect of mannose-binding lectin on cytokine responses: possible roles in HIV infection.
European Journal of Clinical Investigation
Academic article
-
Espevik, Terje.
(2015)
Reconstituted High-Density Lipoprotein Attenuates Cholesterol Crystal-Induced Inflammatory Responses by Reducing Complement Activation.
Journal of Immunology
Academic article
-
Orrem, Hilde Lang;
Nilsson, Per;
Pischke, Søren Erik;
Kleveland, Ola;
Yndestad, Arne;
Ekholt, Karin;
Damås, Jan Kristian;
Espevik, Terje;
Bendz, Bjørn;
Halvorsen, Bente.
(2018)
IL-6 receptor inhibition by tocilizumab attenuated expression of C5a receptor 1 and 2 in non-ST-elevation myocardial infarction.
Frontiers in Immunology
Academic article
-
Dybdahl, Brit;
Slørdahl, Stig Arild;
Waage, Anders;
Kierulf, Peter;
Espevik, Terje;
Sundan, Anders.
(2005)
Myocardial ischaemia and the inflammatory response: release of heat shock protein 70 after myocardial infarction.
Heart
Academic article
-
Hellerud, BC;
Stenvik, Jørgen;
Espevik, Terje;
Lambris, JD;
Mollnes, TE;
Brandtzæg, Petter.
(2008)
Stages of meningococcal sepsis simulated in vitro, with emphasis on complement and Toll-like receptor activation.
Infection and Immunity
Academic article
-
Nilsen, Nadra;
Deininger, S;
Nonstad, Unni;
Skjeldal, F;
Husebye, Harald;
Rodionov, D;
Aulock, S von;
Hartung, T;
Lien, E;
Lien, E.
(2008)
Cellular trafficking of lipoteichoic acid and Toll-like receptor 2 in relation to signaling; role of CD14 and CD36.
Journal of Leukocyte Biology
Academic article
-
Mancuso, Guiseppe;
Midiri, A;
Biondo, Carmelo;
Beninati, C.;
Gambuzza, M;
Macri, D;
Bellantoni, A;
Weintraub, A;
Espevik, Terje;
Teti, Guiseppe.
(2005)
Bacteroides fragilis-derived lipopolysaccharide produces cell activation and lethal toxicity via toll-like receptor 4.
Infection and Immunity
Academic article
-
Manukyan, M;
Triantafilou, K;
Triantafilou, M;
Mackie, A;
Nilsen, Nadra Jesmine;
Espevik, Terje;
Wiesmullers, KH;
Ulmer, AJ;
Heine, H.
(2005)
Binding of lipopeptide to CD14 induces physical proximity of CD14, TLR2 and TLR1.
European Journal of Immunology
Academic article
-
Espevik, Terje.
(2013)
Sensorer som setter i gang betennelse: hvordan virker de og hvorfor trenger vi dem?.
Årbok / Det norske videnskaps-akademi
Popular science article
-
Nilsen, Asbjørn Magne;
Vik, Randi;
Behrens, Carl;
Drabløs, Per Arne;
Espevik, Terje.
(2010)
Beryllium Sensitivity Among Workers at a Norwegian Aluminum Smelter.
American Journal of Industrial Medicine
Academic article
-
Gullestad, Lars;
Aukrust, Pål;
Ueland, Thor;
Espevik, T;
Yee, G.;
Vagelos, R.;
Frøland, Stig Sophus;
Fowler, M.B..
(1999)
Effect of high- versus low-dose angiotensin converting enzyme inhibition on cytokine levels in chronic heart failure.
Journal of the American College of Cardiology
Academic article
-
Yndestad, A;
Landrø, Linn;
Ueland, Thor;
Dahl, CP;
Flo, Trude Helen;
Vinge, Leif Erik;
Espevik, Terje;
Frøland, Stig S;
Husberg, Cathrine;
Christensen, Geir.
(2009)
Increased systemic and myocardial expression of neutrophil gelatinase-associated lipocalin in clinical and experimental heart failure.
European Heart Journal
Academic article
-
Nejati Moharrami, Neda;
Tande, Erlend Bjørkøy;
Ryan, Liv;
Espevik, Terje;
Boyartchuk, Victor.
(2018)
RORα controls inflammatory state of human macrophages.
PLOS ONE
Academic article
-
Christ, Anette;
Günther, Patrick;
Lauterbach, Mario A.R.;
Duewell, Peter;
Biswas, Debjani;
Pelka, Karin;
Scholz, Claus J.;
Oosting, Marije;
Haendler, Kristian;
Baßler, Kevin.
(2018)
Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming.
Cell
Academic article
-
Mollnes, Tom Eirik;
Barratt-Due, Andreas;
Pischke, Søren Erik;
Sandanger, Øystein;
Nunn, Miles A.;
Espevik, Terje;
Denk, Stephanie;
Huber-Lang, Markus.
(2012)
The systemic inflammatory reaction in polymicrobial sepsis induced by murine cecal ligation and puncture is equally dependent on C5 and CD14.
Immunobiology
Conference abstract
-
Johnson, Christina;
Quach, Huy Quang;
Lau, Corinna;
Ekholt, Karin;
Espevik, Terje;
Woodruff, Trent M.;
Pischke, Soeren;
Mollnes, Tom Eirik;
Nilsson, Per.
(2022)
Thrombin Differentially Modulates the Acute Inflammatory Response to Escherichia coli and Staphylococcus aureus in Human Whole Blood.
Journal of Immunology
Academic article
-
Skjåk-Bræk, Gudmund;
Espevik, Terje.
(1996)
Application of alginate gels in biotechnology and biomedicine.
Carbohydrates in Europe
Academic article
-
Landrø, Linn Aina Ysland;
Landro, L;
Damås, Jan Kristian;
Damas, JK;
Flo, Trude Helen;
Heggelund, L;
Ueland, T;
Tjønnfjord, Geir Erland;
Tjonnfjord, GE;
Espevik, Terje.
(2008)
Decreased serum lipocalin-2 levels in human immunodeficiency virus-infected patients: increase during highly active anti-retroviral therapy.
Clinical and Experimental Immunology
Academic article
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Pilely, Katrine;
Rosbjerg, Anne;
Genster, Ninette;
Gál, Peter;
Pál, Gábor;
Halvorsen, Bente;
Holm, Sverre;
Aukrust, Pål;
Bakke, Siril Skaret;
Sporsheim, Bjørnar.
(2016)
Cholesterol crystals activate the lectin complement pathway via ficolin-2 and mannose-binding lectin: Implications for the progression of atherosclerosis.
Journal of Immunology
Academic article
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Landsem, Anne;
Fure, Hilde;
Ludviksen, Judith K;
Christiansen, Dorte;
Lau, Corinna;
Mathisen, Monica Dammen;
Bergseth, Grete;
Nymo, Stig Haugset;
Lappegård, Knut Tore;
Woodruff, T. M..
(2018)
Complement component 5 does not interfere with physiological hemostasis but is essential for Escherichia coli-induced coagulation accompanied by Toll-like receptor 4.
Clinical and Experimental Immunology
Academic article
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Latz, E;
Visintin, A;
Lien, E;
Fitzgerald, KA;
Espevik, Terje;
Golenbock, DT.
(2003)
The LPS receptor generates inflammatory signals from the cell surface.
Journal of Endotoxin Research
Academic article
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Kulseng, Bård Eirik;
Skjåk-Bræk, Gudmund;
Følling, Ivar;
Espevik, Terje.
(1996)
TNF production from peripheral blood mononuclear cells in diabetic patients after stimulation with alginate and lipopolysaccharide.
Scandinavian Journal of Immunology
Academic article
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Thu, Beate;
Bruheim, Per;
Espevik, Terje;
Smidsrød, Olav;
Soon-Shiong, P.;
Skjåk-Bræk, Gudmund.
(1996)
Alginate polycation microcapsules. I, Interaction between alginate and polycation.
Biomaterials
Academic article
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Nørgaard, Nikolai Nordberg;
Holien, Toril;
Jonsson, Sofia;
Hella, Hanne;
Espevik, Terje;
Sundan, Anders;
Standal, Therese.
(2010)
CpG-Oligodeoxynucleotide Inhibits Smad-Dependent Bone Morphogenetic Protein Signaling: Effects on Myeloma Cell Apoptosis and In Vitro Osteoblastogenesis.
Journal of Immunology
Academic article
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Grimstad, Øystein;
Pukstad, Brita;
Stenvik, Jørgen;
Espevik, Terje.
(2010)
TLR3 mediated cytotoxicity in keratinocytes is inhibited by co-stimulation with oligodeoxynucleotides.
Journal of Investigative Dermatology
Conference abstract
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Lien, E.;
Espevik, Terje.
(2000)
Toll-lignende reseptorer - kroppens sensorer for infeksjon.
NBS-nytt
Popular science article
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Stavik, Benedicte;
Holm, Sverre;
Espada Serrano, Sandra;
Iversen, Nina;
Sporsheim, Bjørnar;
Bjerkeli, Vigdis;
Dahl, Tuva Børresdatter;
Sandset, Per Morten;
Skjelland, Mona;
Espevik, Terje.
(2017)
Increased expression of TFPI in human carotid stenosis.
Thrombosis Research
Academic article
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Gregersen, Ida;
Sandanger, Øystein;
Askevold, Erik Tandberg;
Sagen, Ellen Lund;
Yang, Kuan;
Holm, Sverre;
Pedersen, Turid Margrethe;
Skjelland, Mona;
Krohg-Sørensen, Kirsten;
Hansen, Trond Vidar.
(2017)
Interleukin 27 is increased in carotid atherosclerosis and promotes NLRP3 inflammasome activation.
PLOS ONE
Academic article
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Lunde, Ngoc Nguyen Dieu;
Holm, Sverre;
Dahl, Tuva Børresdatter;
Inass, Elyouncha;
Sporsheim, Bjørnar;
Gregersen, Ida;
Abbas, Azhar;
Skjelland, Mona;
Espevik, Terje;
Solberg, Rigmor.
(2016)
Increased levels of legumain in plasma and plaques from patients with carotid atherosclerosis.
Atherosclerosis
Academic article
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Nilsen, Nadra;
Nonstad, Unni;
Kahn, Naseema;
Knetter, Cathrine;
Akira, Shizuo;
Sundan, Anders;
Espevik, Terje;
Lien, Egil.
(2004)
Lipopolysaccharide and Double-stranded RNA Up-regulate Toll-like Receptor 2 Independently of Myeloid Differentiation Factor 88.
Journal of Biological Chemistry
Academic article
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Berntzen, G.;
Flo, T;
Medvedev, A;
Kilaas, L;
Skjåk-Bræk, Gudmund;
Sundan, A;
Espevik, Terje.
(1998)
The tumor necrosis factor-inducing potency of lipopolysaccharide and uronic acid polymers is increased when they are covalently linked to particles.
Clinical and Vaccine Immunology
Academic article
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Kim, Hera;
Subbannayya, Yashwanth;
Humphries, Fiachra;
Skjesol, Astrid;
Pinto, Sneha M.;
Giambelluca, Miriam;
Espevik, Terje;
Fitzgerald, Katherine A.;
Kandasamy, Richard Kumaran.
(2021)
UMP-CMP kinase 2 gene expression in macrophages is dependent on the IRF3-IFNAR signaling axis.
PLOS ONE
Academic article
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Børset, Magne;
Medvedev, Andrei E.;
Sundan, Anders;
Espevik, Terje.
(1996)
The role of the two TNF receptors in proliferation, NF-_KB activation and discrimination between TNF and LT_a signalling in the human myeloma cell line OH-2.
Cytokine
Academic article
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Børset, Magne;
Lien, Egil;
Espevik, Terje;
Helseth, Eirik;
Waage, Anders;
Sundan, Anders.
(1996)
Concomitant expression of hepatocyte growth factor/scatter factor and the receptor c-MET in human myeloma cell lines.
Journal of Biological Chemistry
Academic article
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Austgulen, Rigmor;
Naume, B;
Johnson, A-C;
Espevik, Terje;
Sundan, A.
(1993)
Gene expression and secretion of cytokines and cytokines from highly purified CD56* natural killer cells stimulated with interleukin-2, interleukin-7 and interleukin-12.
European Journal of Immunology
Academic article
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Johnsen, A-C;
Steinkjer, B;
Egeberg, Kathrine;
Sundan, A;
Espevik, Terje.
(1999)
The role of international-2 in regulation the sensitivity of natural killer celler for Fas-mediated apoptosis.
European Journal of Haematology
Academic article
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Lien, E;
Nonstad, Unni;
Sundan, A;
Espevik, Terje.
(1999)
Polymorphonuchlear of Fas and Fas-Ligand expression in NK cells by cytokines and the involved of Fas-Ligand in NK/LAK cell-mediated cytotoxicity.
Cytokine
Academic article
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Halaas, Øyvind;
Liabakk, Nina-Beate;
Vik, Randi;
Beninati, C;
Henneke, P;
Sundan, Anders;
Espevik, Terje.
(2004)
Monocytes stimulated with group B Streptococci or interferons release tumour necrosis factor-related apoptosis-inducing ligand.
Scandinavian Journal of Immunology
Academic article
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Thomas, Anub Mathew;
Gerogianni, Alexandra;
McAdam, Martin Berner;
Fløisand, Yngvar;
Lau, Corinna;
Espevik, Terje;
Nilsson, Per;
Mollnes, Tom Eirik;
Barratt-Due, Andreas.
(2019)
Complement component C5 and TLR molecule CD14 mediate heme-induced thromboinflammation in human blood.
Journal of Immunology
Academic article
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Kleveland, Ola;
Kunszt, Gabor;
Bratlie, Marte;
Ueland, Thor;
Broch, Kaspar;
Holte, Espen;
Michelsen, Annika;
Bendz, Bjørn;
Amundsen, Brage H.;
Espevik, Terje.
(2016)
Effect of a single dose of the interleukin-6 receptor antagonist tocilizumab on inflammation and troponin T release in patients with non-ST-elevation myocardial infarction: a double-blind, randomized, placebo-controlled phase 2 trial.
European Heart Journal
Academic article
-
Pukstad, Brita;
Ryan, Liv;
Flo, Trude Helen;
Stenvik, Jørgen;
Moseley, Ryan;
Harding, Keith;
Thomas, David W.;
Espevik, Terje.
(2010)
Non-healing is associated with persistent stimulation of the innate immune response in chronic venous leg ulcers.
Journal of dermatological science (Amsterdam)
Academic article
-
Grimstad, Øystein;
Pukstad, Brita;
Stenvik, Jørgen;
Espevik, Terje.
(2012)
Oligodeoxynucleotides inhibit Toll-like receptor 3 mediated cytotoxicity and CXCL8 release in keratinocytes.
Experimental Dermatology
Academic article
-
Aukrust, Pål;
Lien, Egil;
Kristoffersen, Anne K.;
Müller, Fredrik;
Haug, Charlotte J.;
Espevik, Terje;
Frøland, Stig S..
(1996)
Persistent activation of the tumor necrosis factor system in a subgroup of patients with common variable immunodeficiency : possible immunologic and clinical consequences.
Blood
Academic article
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Jahr, Tove Gullstein;
Ryan, Liv;
Sundan, Anders;
Lichenstein, Henri S.;
Skjåk-Bræk, Gudmund;
Espevik, Terje.
(1997)
Induction of tumor necrosis factor production from monocytes stimulated with mannuronic acid polymers and involvement of lipopolysaccharide-binding protein, CD14, and bactericidal/ permeability-increasing factor.
Infection and Immunity
Academic article
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Stavik, Benedicte;
Espada, Sandra;
Holm, Sverre;
Bjerkeli, Vigdis;
Sandset, Per Morten;
Dahl, Tuva Børresdatter;
Skjelland, Mona;
Espevik, Terje;
Iversen, Nina;
Skretting, Grethe.
(2017)
TFPI in human atherosclerotic plaques.
Research and Practice in Thrombosis and Haemostasis (RPTH)
Conference abstract
-
Nilsen, N;
Nonstad, U;
Khan, N;
Knetter, Cathrine;
Akira, S;
Sundan, Anders;
Espevik, Terje;
Lien, E.
(2004)
Lipopolysaccharide and double-stranded RNA up-regulate toll-like receptor 2 independently of myeloid differentiation factor 88.
Journal of Biological Chemistry
Academic article
-
Mollnes, Tom Eirik;
Christiansen, D;
Brekke, Ole Lars;
Espevik, T.
(2008)
Hypothesis: Combined inhibition of complement and CD14 as treatment regimen to attenuate the inflammatory response.
Advances in Experimental Medicine and Biology
Academic article
-
Østvik, Ann Elisabet;
Granlund, Atle Van Beelen;
Gustafsson, Björn;
Torp, Sverre Helge;
Espevik, Terje;
Mollnes, Tom Eirik;
Damås, Jan Kristian;
Sandvik, Arne Kristian.
(2014)
Mucosal toll-like receptor 3-dependent synthesis of complement factor B and systemic complement activation in inflammatory bowel disease.
Inflammatory Bowel Diseases
Academic article
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Lau, Corinna;
Gunnarsen, Kristin Støen;
Høydahl, Lene Støkken;
Berntzen, Gøril;
Stokes, Christopher R.;
Espevik, Terje;
Sandlie, Inger;
Mollnes, Tom Eirik.
(2012)
Recombinant anti-human and anti-porcine CD14 antibodies.
Immunobiology
Conference abstract
-
Heggelund, L;
Flo, Trude Helen;
Berg, K.;
Lien, E;
Espevik, Terje.
(2004)
Soluble toll-like receptor 2 in HIV infection: association with disease progression.
AIDS (London)
Academic article
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Pilely, Katrine;
Bakke, Siril Skaret;
Palarasah, Yaseelan;
Skjoedt, Mikkel-Ole;
Bartels, Emil D.;
Espevik, Terje;
Garred, Peter.
(2019)
Alpha-cyclodextrin inhibits cholesterol crystal-induced complement-mediated inflammation: A potential new compound for treatment of atherosclerosis.
Atherosclerosis
Academic article
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Austgulen, Rigmor;
Kjøllesdal, AM;
Johnsen, H;
Liabakk, N-B;
Espevik, Terje.
(1993)
Soluble receptors for tumor necrosis factor: occurence in association with normal delivery at term.
Obstetrics and Gynecology
Academic article
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Austgulen, Rigmor;
Liabakk, N-B;
Lien, E;
Espevik, Terje.
(1993)
Increased levels of soluble TNF-alpha receptors in serum from pregnant women, and in serum and urine samples from newborns.
Pediatric Research
Academic article
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Arntzen, KJ;
Liabakk, N-B;
Jacobsen, G.;
Espevik, Terje;
Austgulen, Rigmor.
(1995)
Soluble tumor necrosis factor receptor in serum and urine througout normal pregnancy and delivery.
American Journal of Reproductive Immunology
Academic article
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Austgulen, Rigmor;
Espevik, Terje;
Mecsei, R;
Scott, H.
(1992)
Expression of receptors for tumor necrosis factor in human placenta at term.
Acta Obstetricia et Gynecologica Scandinavica
Academic article
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Aukrust, Pål;
Muller, Fredrik;
Lien, Egil;
Nordøy, Ingvild;
Liabakk, Nina-Beate;
Kvale, Dag;
Espevik, T;
Frøland, Stig Sophus.
(1999)
Tumor necrosis factor (TNF) system in human immunodeficiency virus-infected patients during highly active antiretroviral therapy (HAART): Persistent TNF activation is associated with virologic and immunologic treatment failure.
Journal of Infectious Diseases
Academic article
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Aukrust, Pål;
Haug, Charlotte J.;
Ueland, Thor;
Lien, Egil;
Muller, Fredrik;
Espevik, T;
Bollerslev, Jens;
Frøland, Stig Sophus.
(1999)
Decreased bone formative and enhanced resorptive markers in human immunodeficiency virus infection: indication of normalization of the bone-remodeling process during highly active antiretroviral therapy.
Journal of Clinical Endocrinology and Metabolism (JCEM)
Academic article
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Aukrust, Pål;
Ueland, Thor;
Lien, Egil;
Bendtzen, Klaus;
Muller, Fredrik;
Andreassen, Arne K.;
Nordøy, Ingvild;
Aass, Halfdan;
Espevik, T;
Simonsen, Svein.
(1999)
Cytokine network in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy.
American Journal of Cardiology
Academic article
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Strand, Berit Løkensgard;
Mørch, Yrr Asbjørg;
Espevik, Terje;
Skjåk-Bræk, Gudmund.
(2003)
Visualization of alginate-poly-L-lysine-alginate microcapsules by confocal laser scanning microscopy.
Biotechnology and Bioengineering
Academic article
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Flo, T.H.;
Ryan, L.;
Kilaas, L.;
Skjåk-Bræk, Gudmund;
Ingalls, R.R.;
Sundan, A.;
Golenbock, D.T.;
Espevik, Terje.
(2000)
Involvement of CD14 and beta2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers.
Infection and Immunity
Academic article
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Iversen, Ann-Charlotte;
Sundan, Anders;
Espevik, Terje.
(2001)
IFN-alpha(2b) and IFN-beta induce TRAIL-mediated NK cell cytotoxicity.
The FASEB Journal
Conference abstract
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Heggelund, L;
Mollnes, TE;
Espevik, Terje;
Muller, F;
Kristiansen, KI;
Aukrust, P;
Frøland, Stig S.
(2005)
Modulatory effect of mannose-binding lectin on cytokine responses: roles in HIV infection.
European Journal of Clinical Investigation
Academic article
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Liabakk, N-B;
Lien, E;
Sundan, A;
Sunde, A;
Austgulen, Rigmor;
Espevik, Terje.
(1993)
High concentrations of the soluble p55 tumor necrosis factor receptor in human seminal plasma.
Human Reproduction
Academic article
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Halgunset, J;
Johnsen, H;
Kjøllesdal, AM;
Qvigstad, E;
Espevik, Terje;
Austgulen, Rigmor.
(1994)
Normal parturition at term is associated with subtle inflammatory reactions in-utero.
European Journal of Obstetrics, Gynecology, and Reproductive Biology
Academic article
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Lau, Corinna;
McAdam, Martin Berner;
Bergseth, Grete;
Grevys, Algirdas;
Bruun, Jack-Ansgar;
Ludviksen, Judith K;
Fure, Hilde;
Espevik, Terje;
Moen, Anders;
Andersen, Jan Terje.
(2019)
NHDL, a recombinant VL/VH hybrid antibody control for IgG2/4 antibodies.
mAbs
Academic article
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Strand, Berit Løkensgard;
Mørch, Yrr Asbjørg;
Syvertsen, Kjersti R.;
Espevik, Terje;
Skjåk-Bræk, Gudmund.
(2003)
Microcapsules made by enzymatically tailored alginate.
Journal of Biomedical Materials Research
Academic article
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Waage, A.;
Halstensen, Alfred;
Espevik, T.;
Brandtzæg, P..
(1994)
Cytokines in meningococcal disease.
Baillière's Clinical Infectious Diseases
Academic article
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Austgulen, Rigmor;
Liabakk, N-B;
Espevik, Terje.
(1992)
Sekresjon av løselige reseptorer for tumor nekrose faktor - en immunologisk buffermekanisme under svangerskap?.
Tidsskrift for Den norske legeforening (Tidsskriftet)
Academic article
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Grimstad, Øystein;
Husebye, Harald;
Espevik, Terje.
(2013)
TLR3 mediates release of IL-1 beta and cell death in keratinocytes in a caspase-4 dependent manner.
Journal of dermatological science (Amsterdam)
Academic article
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Granlund, Atle Van Beelen;
Flatberg, Arnar;
Østvik, Ann Elisabet;
Drozdov, Ignat;
Gustafsson, Björn;
Kidd, Mark;
Beisvag, Vidar;
Torp, Sverre Helge;
Waldum, Helge;
Martinsen, Tom Christian.
(2013)
Whole Genome Gene Expression Meta-Analysis of Inflammatory Bowel Disease Colon Mucosa Demonstrates Lack of Major Differences between Crohn's Disease and Ulcerative Colitis.
PLOS ONE
Academic article
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Husebye, Harald;
Aune, Marie Hjelmseth;
Stenvik, Jørgen;
Samstad, Eivind Ottersen;
Skjeldal, Frode Miltzow;
Halaas, Øyvind;
Nilsen, Nadra;
Stenmark, Harald Alfred;
Latz, Eicke;
Lien, Egil.
(2010)
The Rab11a GTPase Controls Toll-like Receptor 4-Induced Activation of Interferon Regulatory Factor-3 on Phagosomes.
Immunity
Academic article
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Sugawara, Shunji;
Yang, Shuhua;
Iki, Koichi;
Hatakeyama, Junko;
Tamai, Riyoko;
Takeuchi, Osamu;
Akashi, Sachiko;
Espevik, Terje;
Akira, Shizuo;
Takada, Haruhiko.
(2001)
Monocytic cell activation by nonendotoxic glycoprotein from Prevotella intermedia ATCC 25611 is mediated by Toll-like receptor 2.
Infection and Immunity
Academic article
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Kulseng, Bård Eirik;
Espevik, Terje;
Skjåk-Bræk, Gudmund.
(1999)
Behandling av diabetes mellitus med transplantasjon av immunbeskyttet øyvev fra pancreas.
Tidsskrift for Den norske legeforening (Tidsskriftet)
Academic article
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Mori, Y;
Yoshimura, A;
Ukai, T;
Lien, Egil;
Espevik, Terje;
Hara, Y.
(2003)
Immunohistochemical localization of Toll-like receptors 2 and 4 in gingival tissue from patients with periodontitis.
Oral Microbiology and Immunology
Academic article
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Adib-Conquy, M;
Moine, P;
Asehnoune, K;
Edouard, A;
Espevik, Terje;
Miyake, K;
Werts, C;
Cavaillon, J-M.
(2003)
Toll-like receptor-mediated tumor necrosis factor and interleukin-10 production differ during systemic inflammation.
American Journal of Respiratory and Critical Care Medicine
Academic article
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Sandanger, Øystein;
Ranheim, Trine;
Vinge, Leif Erik;
Bliksøen, Marte;
Alfsnes, Katrine;
Finsen, Alexandra;
Dahl, Christen Peder;
Askevold, Erik Tandberg;
Florholmen, Geir;
Christensen, Geir Arve.
(2013)
The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury.
Cardiovascular Research (CVR)
Academic article
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Rokstad, Anne Mari;
Brekke, Ole Lars;
Steinkjer, Bjørg;
Ryan, Liv;
Kolláriková, Gabriela;
Strand, Berit Løkensgard;
Skjåk-Bræk, Gudmund;
Lambris, John D.;
Lacík, Igor;
Mollnes, Tom Eirik.
(2013)
The induction of cytokines by polycation containing microspheres by a complement dependent mechanism.
Biomaterials
Academic article
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Gravastrand, Caroline S.;
Steinkjer, Bjørg;
Halvorsen, Bente;
Landsem, Anne;
Skjelland, Mona;
Jacobsen, Eva Astrid;
Woodruff, Trent M.;
Lambris, John D.;
Mollnes, Tom Eirik;
Brekke, Ole-Lars.
(2019)
Cholesterol Crystals Induce coagulation Activation through Complement-Dependent Expression of Monocytic Tissue Factor.
Journal of Immunology
Academic article
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Hetland, Geir;
Tryggestad, Anne Merete Aaland;
Espevik, Terje;
Ryan, Liv;
Tangen, Jon-Magnus;
Johnson, Egil;
Kvalheim, Gunnar.
(2010)
The Medicinal and Antitumor Mushroom, Agaricus Blazei Murill, Activates NF-kappa B Via TLR2 but Not TLR4 In Monocytic Cells, and Stimulates Monocyte-Derived Dendritic Cells (MDDC) to Increased Cell Surface Marker Expression and Cytokine Production, and May Thus Have Adjuvant Effect In MDDC Cancer Vaccines.
Blood
Conference abstract
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Nissen-Meyer, J;
Austgulen, Rigmor;
Espevik, Terje.
(1988)
Synergistic growth inhibitory activity of tumor necrosis factor and interferon-alpha: contribution to the monocyte-derived cytostatic activity towards human leukemia K562 cells.
Scandinavian Journal of Immunology
Academic article
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Austgulen, Rigmor;
Liabakk, N-B;
Richardsen, W;
Rahimipoor, S;
Vatn, I;
Espevik, Terje.
(1993)
Serum levels of soluble TNF receptors are influenced by gestational age and delivery in normal pregnancy.
Placenta
Conference abstract
-
Nilsen, Nadra;
I., Vladimer Gregory;
Stenvik, Jørgen;
Ørning, Mathias Pontus;
Zeid-Kilani, Maria Vanessa;
Bugge, Marit;
Bergstrøm, Bjarte;
Conlon, Joseph;
Husebye, Harald;
Amy, Hise.
(2015)
A role for the adaptor proteins TRAM and TRIF in toll-like receptor 2 signaling.
Journal of Biological Chemistry
Academic article
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Flo, Trude Helen;
Halaas, Øyvind;
Lien, Egil;
Ryan, Liv;
Teti, Guiseppe;
Golenbock, Douglas T.;
Sundan, Anders;
Espevik, Terje.
(2000)
Human Toll-like Receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide.
Journal of Immunology
Academic article
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Lau, Corinna;
Gunnarsen, Kristin Støen;
Høydahl, Lene Støkken;
Andersen, Jan Terje;
Berntzen, Gøril;
Pharo, Anne Margrethe;
Lindstad, Julie Katrine;
Ludviksen, Judith K;
Brekke, Ole Lars;
Barratt-Due, Andreas.
(2013)
Chimeric Anti-CD14 IGG2/4 Hybrid Antibodies for Therapeutic Intervention in Pig and Human Models of Inflammation.
Journal of Immunology
Academic article
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Heggelund, L;
Mollnes, TE;
Espevik, Terje;
Muller, F;
Kristiansen, KI;
Aukrust, P;
Froland, SS.
(2005)
Modulatory effect of mannose-binding lectin on cytokine resposes: possible roles in HIV infection.
European Journal of Clinical Investigation
Academic article
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Henneke, Philipp;
Takeuchi, Osamu;
Strijp, JA van;
Guttormsen, HK;
Smith, JA;
Schromm, Andra;
Espevik, Terje;
et, al..
(2001)
Novel engagement of CD14 and multiple toll-like receptors by group B streptococci.
Journal of Immunology
Academic article
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Halaas, Øyvind;
Husebye, Harald;
Espevik, Terje.
(2007)
The journey of Toll-like receptors in the cell.
Advances in Experimental Medicine and Biology
Academic article
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Liabakk, Nina-Beate;
Sundan, Anders;
Torp, Sverre Helge;
Aukrust, Pål;
Frøland, Stig Sophus;
Espevik, Terje.
(2002)
Development, characterization and use of monoclonal antibodies against sTRAIL measurement of sTRAIL by ELISA.
Journal of Immunological Methods (JIM)
Academic article
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Austgulen, Rigmor;
Liabakk, N-B;
Scott, H;
Brockhaus, M;
Espevik, Terje.
(1991)
Soluble TNF receptors in urine and in amniotic fluid from pregnant women.
Placenta
Conference abstract
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Johnsen, Ingvild Bjellmo;
Nguyen, Thank Thuy Thi;
Ringdal, Monika;
Tryggestad, AM;
Bakke, Oddmund;
Lien, Egil;
Espevik, Terje;
Anthonsen, Marit Walbye.
(2006)
Toll-like receptor 3 associates with c-Src tyrosine kinase on endosomes to initiate antiviral signaling.
EMBO Journal
Academic article
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Nilsen, Kaja Elisabeth;
Zhang, Boyao;
Skjesol, Astrid;
Ryan, Liv;
Vagle, Hilde;
Bøe, Maren Helene;
Ørning, Mathias Pontus;
Kim, Hera;
Bakke, Siril Skaret;
Elamurugan, Kirusika.
(2023)
Peptide derived from SLAMF1 prevents TLR4-mediated inflammation in vitro and in vivo.
Life Science Alliance (LSA)
Academic article
-
Kleij, D van der;
Latz, Eicke;
Brouwers, JF;
Kruize, YC;
Schmitz, M;
Kurt-Jones, EA;
Espevik, Terje;
Jong, EC de;
Kapsenberg, ML;
Golenbock, Douglas T..
(2002)
A novel host-parasite lipid cross-talk. Schistosomal lyso-phosphatidylserine activates Toll-like recepytor 2 and affects immune polarization.
Journal of Biological Chemistry
Academic article
-
Zimmer, Sebastian;
Grebe, Alena;
Bakke, Siril Skaret;
Bode, Niklas;
Halvorsen, Bente;
Ulas, Thomas;
Skjelland, Mona;
Nardo, Dominic De;
Labzin, Larisa I.;
Kerksiek, Anja.
(2016)
Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming.
Science Translational Medicine
Academic article
-
Johnsen, Ann-Charlotte;
Haux, Johan;
Steinkjer, Bjørg;
Nonstad, Unni;
Egeberg, Kjartan Wøllo;
Sundan, Anders;
Ashkenazi, Avi;
Espevik, Terje.
(1999)
Regulation of APO-2 ligand /Trail expression in NK cells - involvement in NK cell-mediated cytotoxicity.
Cytokine
Academic article
-
Hetland, G;
Tryggestad, AMA;
Forland, T;
Johnson, E;
Ryan, L;
Espevik, Terje.
(2008)
Proposed immunomodulatory co-therapy for hematological cancer by the medicinal mushroom Agaricus blazei Murill, is facilitated by its stimulation of TLR2 and activation of NF-KB.
Vox Sanguinis
Conference abstract
-
Nørgaard, Nikolai Nordberg;
Holien, Toril;
Jönsson, S;
Hella, Hanne;
Espevik, Terje;
Sundan, Anders;
Standal, Therese.
(2011)
CpG-ODN inhibits Smad-dependent BMP signaling; Effects on myeloma cell apoptosis and in vitro osteoblastogenesis.
Bone
Conference abstract
-
Nordgård, Catherine Taylor;
Nonstad, Unni;
Olderøy, Magnus Østgård;
Espevik, Terje;
Draget, Kurt Ingar.
(2014)
Alterations in mucus barrier function and matrix structure induced by guluronate oligomers.
Biomacromolecules
Academic article
-
Latz, E;
Verma, Anjali;
Visintin, A;
Gong, Mei;
Sirois, CM;
Klein, Dionne;
Monks, BG;
Mcknight, C. james;
Duprex, W. paul;
Espevik, Terje.
(2007)
Corrigendum: Ligand-induced conformational changes allosterically activate Toll-like receptor 9.
International Immunology
Academic article
-
Waage, A.;
Halstensen, Alfred;
Espevik, T.;
Brandtzæg, P..
(1993)
Compartmentalization of the TNF and IL-6 in meningitis and septic shock.
Mediators of Inflammation
Academic article
-
Damås, Jan Kristian;
Davi, Giovanni;
Jensenius, M;
Santilli, F;
Otterdal, K;
Ueland, T;
Flo, Trude Helen;
Lien, E;
Espevik, Terje;
Frøland, Stig S.
(2009)
Relative chemokine and adhesion molecule expression in Mediterranean spotted fever and African tick bite fever.
Journal of Infection
Academic article
-
Nymo, Stig Haugset;
Niyonzima, Nathalie;
Espevik, Terje;
Mollnes, Tom Eirik.
(2014)
Cholesterol crystal-induced endothelial cell activation is complement-dependent and mediated by TNF.
Immunobiology
Academic article
-
Klein, Dionne;
Øvrebø, Kirsti Marie;
Latz, Eicke;
Espevik, Terje;
Stokke, Bjørn Torger.
(2012)
Direct measurement of the interaction force between immunostimulatory CpG-DNA and TLR9 fusion protein.
Journal of Molecular Recognition
Academic article
-
Skjeflo, Espen Waage;
Sagatun, Caroline;
Dybwik, Knut;
Aam, Sturla;
Urving, Sven Haakon;
Nunn, Miles A.;
Fure, Hilde;
Lau, Corinna;
Brekke, Ole Lars;
Huber-Lang, Markus.
(2015)
Combined inhibition of complement and CD14 improved outcome in porcine polymicrobial sepsis.
Critical Care
Academic article
-
Schjetne, KW;
Thompson, Keith;
Fleckenstein, Burkhard;
Aarvak, Tanja;
Flo, T. H.;
Iversen, Jens Gustav;
Espevik, T;
Bogen, Bjarne.
(2003)
Cutting edge: Link between innate and adaptive immunity: toll like receptor 2 (TLR 2) captures antigen for MHC class II presentation to CD4+ T cell responses.
Journal of Immunology
Academic article
-
Østvik, Ann Elisabet;
Granlund, Atle Van Beelen;
Torp, Sverre Helge;
Flatberg, Arnar;
Beisvag, Vidar;
Waldum, Helge;
Flo, Trude Helen;
Espevik, Terje;
Damås, Jan Kristian;
Sandvik, Arne Kristian.
(2013)
Expression of Toll-like receptor-3 is enhanced in active inflammatory bowel disease and mediates the excessive release of lipocalin 2.
Clinical and Experimental Immunology
Academic article
-
Brandtzæg, P.;
Halstensen, Alfred;
Kierulf, P.;
Espevik, T.;
Waage, A..
(1992)
Molecular mechanisms in the compartmentalized inflammatory response presenting as meningococcal meningitis or septic shock.
Microbial Pathogenesis
Academic article
-
Aukrust, Pål;
Hestad, Kjetil;
Lien, Egil;
Bjerkeli, Vigdis;
Nordøy, Ingvild;
Espevik, T;
Muller, Fredrik;
Frøland, Stig Sophus.
(1997)
Effects of intravenous immunoglobulin in vivo on abnormally increased tumor necrosis factor-_a activity in human immunodeficiency virus type 1 infection.
Journal of Infectious Diseases
Academic article
-
Hestad, Kjetil;
Aukrust, Pål;
Muller, Fredrik;
Lien, Egil;
Bjerkeli, Vigdis;
Espevik, T;
Frøland, Stig Sophus.
(1997)
Dysregulation of membrane-bound tumor necrosis factor-_a and tumor necrosis factor receptors on mononuclear cells in human immunodeficiency virus type 1 infection: Low percentage of p75-tumor necrosis factor receptor positive cells in patients with advanced disease and high viral load.
Blood
Academic article
-
Lentini, Germana;
Famà, Agata;
Gaetano, Giuseppe Valerio De;
Coppolino, Francesco;
Mahjoub, Ahlem Khachroub;
Ryan, Liv;
Lien, Egil;
Espevik, Terje;
Beninati, Concetta;
Teti, Giuseppe.
(2023)
Caspase-8 inhibition improves the outcome of bacterial infections in mice by promoting neutrophil activation.
Cell Reports Medicine
Academic article
-
Ehrnstrøm, Birgitta;
Beckwith, Kai Sandvold;
Yurchenko, Mariya;
Moen, Siv Helen;
Kojen, June Frengen;
Lentini, Germana;
Teti, Guiseppe;
Damås, Jan Kristian;
Espevik, Terje;
Stenvik, Jørgen.
(2017)
Toll-Like Receptor 8 Is a Major Sensor of Group B Streptococcus But Not Escherichia coli in Human Primary Monocytes and Macrophages.
Frontiers in Immunology
Academic article
-
Grimstad, Øystein;
Sandanger, Øystein;
Ryan, Liv;
Otterdal, Kari;
Damås, Jan Kristian;
Pukstad, Brita;
Espevik, Terje.
(2011)
Cellular sources and inducers of cytokines present in acute wound fluid.
Wound Repair and Regeneration
Academic article
-
Niyonzima, Nathalie;
Freeley, Simon;
Arbore, Giuseppina;
Friec, Gaelle Le;
Lappegård, Knut Tore;
Mollnes, Tom Eirik;
Kemper, Claudia;
Espevik, Terje.
(2016)
The intracellular C5 system is critical to DAMP sensing and cellular responses in human monocytes.
Immunobiology
Conference abstract
-
Arlov, Øystein;
Aachmann, Finn Lillelund;
Sundan, Anders;
Espevik, Terje;
Skjåk-Bræk, Gudmund.
(2014)
Heparin-Like Properties of Sulfated Alginates with Defined Sequences and Sulfation Degrees.
Biomacromolecules
Academic article
-
Ellingsen, E.A.;
Morath, S;
Flo, Trude Helen;
Schromm, Andra;
Hartung, T;
Thiemermann, C;
Espevik, Terje;
Golenbock, Douglas T.;
Foster, D;
Solberg, R..
(2002)
Induction of cytokine production in human T cells and monocytes by highly purified lipoteichoic acid: involvement of Toll-like receptors and CD14.
Medical Science Monitor
Academic article
-
Dybdahl, Brit;
Wahba, Alexander;
Lien, Egil;
Flo, Trude Helen;
Waage, Anders;
Sellevold, Olav F Münter;
Espevik, Terje;
Sundan, Anders;
Qureshi, Nilofer.
(2002)
Inflammatory response after open heart surgery: release of heat-shock protein 70 and signaling through toll-like receptor-4.
Circulation
Academic article
-
Latz, Eicke;
Visintin, A;
Lien, Egil;
Fitzgerald, KA;
Monks, Brian G.;
Kurt-Jones, EA;
Golenbock, Douglas T.;
Espevik, Terje.
(2002)
Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the Toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction.
Journal of Biological Chemistry
Academic article
-
Rokstad, Anne Mari;
Strand, Berit Løkensgard;
Espevik, Terje;
Mollnes, Tom Eirik.
(2013)
Biocompatibility and Biotolerability Assessment of Microspheres Using a Whole Blood Model.
Micro and Nanosystems
Academic article
-
Belge, KU;
Dayyani, F;
Horelt, A;
Siedlar, M;
Frankenberger, M;
Frankenberger, B;
Espevik, Terje;
Ziegler-Heitbrock, L.
(2002)
The proinflammatory CD14+CD16+DR++ monocytes are a major source of TNF.
Journal of Immunology
Academic article
-
Tamai, Riyoko;
Sakuta, T;
Matsushita, K;
Torii, M;
Takeuchi, Osamu;
Akira, Shizuo;
Akashi, Sachiko;
Espevik, Terje;
Sugawara, Shunji;
Takada, Haruhiko.
(2002)
Human gingival CD14(+) fibroblasts primed with gamma interferon increase production of interleukin-8 in response to lipopolysaccharide through up-regulation of membrane CD14 and MyD88 mRNA expression.
Infection and Immunity
Academic article
-
Latz, Eicke;
Verma, Anjali;
Visintin, A;
Gong, Mei;
Sirois, Cherilyn m.;
Klein, Dionne;
Monks, Brian G.;
Mcknight, C. james;
Lamphier, Marc s.;
Duprex, W. paul.
(2007)
Ligand-induced conformational changes allosterically activate Toll-like receptor 9.
Nature Immunology
Academic article
-
Christiansen, Dorte;
Brekke, Ole Lars;
Stenvik, Jørgen;
Lambris, J.D.;
Espevik, Terje;
Mollnes, Tom Eirik.
(2012)
Differential Effect of Inhibiting MD-2 and CD14 on LPS- Versus Whole E. coli Bacteria-Induced Cytokine Responses in Human Blood.
Advances in Experimental Medicine and Biology
Academic article
-
Gustavsen, Alice;
Nymo, Stig Haugset;
Landsem, Anne;
Christiansen, Dorte;
Ryan, Liv;
Husebye, Harald;
Lau, Corinna;
Pischke, Søren Erik;
Lambris, John D.;
Espevik, Terje.
(2016)
Combined inhibition of complement and CD14 attenuates bacteria-induced inflammation in human whole blood more efficiently than antagonizing the toll-like receptor 4-MD2 complex.
Journal of Infectious Diseases
Academic article
-
Christiansen, D;
Brekke, Ole Lars;
Stenvik, Jørgen;
Lambris, JD;
Espevik, Terje;
Mollnes, Tom Eirik.
(2010)
Differential effect of inhibiting MD-2 and CD14 on LPS- versus whole E. coli bacteria-induced cytokine responses in human blood.
Molecular Immunology
Conference abstract
-
Islam, Rakibul;
Islam, Mohammad Mirazul;
Nilsson, Per H.;
Mohlin, Camilla;
Hagen, Kjersti Thorvaldsen;
Paschalis, Eleftherios I.;
Woods, Russell L.;
Bhowmick, Sabuj Chandra;
Dohlman, Claes H.;
Espevik, Terje.
(2021)
Combined blockade of complement C5 and TLR co-receptor CD14 synergistically inhibits pig-to-human corneal xenograft induced innate inflammatory responses.
Acta Biomaterialia
Academic article
-
Ørning, Mathias Pontus;
Hoem, Kine Samset;
Coron, Abba Elizabeth;
Skjåk-Bræk, Gudmund;
Mollnes, Tom Eirik;
Brekke, Ole Lars;
Espevik, Terje;
Rokstad, Anne Mari.
(2016)
Alginate microsphere compositions dictate different mechanisms of complement activation with consequences for cytokine release and leukocyte activation.
Journal of Controlled Release
Academic article
Books
-
Klein, Dionne C.G.;
Latz, Eicke;
Espevik, Terje;
Stokke, Bjørn Torger.
(2008)
Effects of CpG-DNA on Toll-like receptor 9 studied by AFM.
TRAUNER Verlag
Anthology
-
Rokstad, Anne Mari Aukan;
Bjerkvig, Rolf;
Espevik, Terje;
Lund-Johansen, M.
(2005)
Applications of Cell Immobilisation Biotechnology, Focus on Biotechnology.
Book chapter: Cell encapsulation therapy for malignant gliomas.
Springer
Anthology
-
Espevik, Terje;
Waage, Anders;
Sundan, A..
(2000)
Summary of the 8 th International TNF Congress. Trondheim.
NBS-nytt
Non-fiction monograph
Part of book/report
-
Espevik, Terje;
Rokstad, Anne Mari;
Kulseng, Bård Eirik;
Strand, Berit Løkensgard;
Skjåk-Bræk, Gudmund.
(2009)
Mechanisms of the host immune response to alginate microcapsules.
Non-fiction chapter
-
Halaas, Øyvind;
Husebye, Harald;
Stenmark, Harald;
Espevik, Terje.
(2008)
Intracellular Trafficing of Toll-like Receptors.
Academic chapter
-
Waage, A.;
Halstensen, Alfred;
Brandtzæg, P.;
Espevik, T..
(1992)
TNF in serum in patients with bacterial infections.
Academic chapter
Report
-
Espevik, Terje;
Waage, Anders;
Sundan, Anders.
(2000)
Summary of the 8th International TNF Congress, Trondheim, May 14-18, 2000.
STENS trykkeri
Research report
-
Jenssen, Jon A;
Espevik, Terje.
(2001)
Cellebiologisk metode for å påvise biologisk aktivitet av svevestøv.
SINTEF AS
Research report
-
Nilsen, Asbjørn Magne;
Vik, Randi;
Espevik, Terje.
(2006)
Be-LPT testing at Hydro Aluminium Karmøy AS. Final Report. June 2006.
Norwegian University of Science and Technology
Research report
-
Nilsen, Asbjørn Magne;
Vik, Randi;
Espevik, Terje.
(2006)
Be-LPT testing Karmøy. Undervegsrapport 3. Mars 2006.
Norges teknisk-naturvitenskapelige universitet
Research report
-
Nilsen, Asbjørn Magne;
Vik, Randi;
Espevik, Terje.
(2006)
Be-LPT testing Karmøy. Undervegsrapport 4. April 2006.
Norges teknisk-naturvitenskapelige universitet
Research report
-
Nilsen, Asbjørn Magne;
Vik, Randi;
Espevik, Terje.
(2006)
BeLPT testing Karmøy. Undervegsrapport 1. Januar 2006.
Norges teknisk-naturvitenskapelige universitet
Research report
-
Nilsen, Asbjørn Magne;
Vik, Randi;
Espevik, Terje.
(2006)
Be-LPT testing Karmøy. Undervegsrapport 2. Februar 2006.
Norges teknisk-naturvitenskapelige universitet
Research report
-
Skjåk-Bræk, Gudmund;
Espevik, Terje;
Otterlei, Marit;
Smidsrød, Olav;
Soon-Shiong, P..
(1995)
Homologous guluronic acid alginate coating composition for in vivo application and implantation and method using the same.
[Mangler utgivernavn]
Research report
Student thesis or dissertation
-
Nejati Moharrami, Neda;
Boyartchuk, Victor;
Espevik, Terje.
(2018)
Role of CD5L in control of human innate immune function.
Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
-
Sherstova, Tatyana;
Stokke, Bjørn Torger;
Anthonsen, Marit Walbye;
Espevik, Terje.
(2016)
Quantitative atomic force microscopy and light microscopy of hydrogels and cells.
Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
-
Bugge, Marit;
Nilsen, Nadra J.;
Espevik, Terje.
(2016)
Toll-Like Receptor 3 Signaling in Intestinal Epithelial Cells.
Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
-
Bösl, Korbinian;
Kandasamy, Richard Kumaran;
Espevik, Terje.
(2019)
Novel insights on human-virus interactions through genome-wide approaches.
Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
-
Nilsen, Nadra;
Espevik, Terje;
Lien, Egil.
(2008)
TOLL-LIKE RECEPTOR 2 EXPRESSION, REGULATION AND SIGNALING.
Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Outreach
2025
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Conference posterKristensen, Stine; Årseth, Charlotte; Ryan, Liv; Ullmann, Sindre; Lambris, John D.; Mollnes, Tom Eirik; Flo, Trude Helen; Husebye, Harald; Espevik, Terje. (2025) Exploring the role of intracellular C3 in activation of the NLRP3 inflammasome in human macrophages. International Complement Workshop 2025
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Conference lectureÅrseth, Charlotte; Kristensen, Stine; Yurchenko, Maria; Ryan, Liv; Rasheed, Kashif; Ullmann, Sindre; Husebye, Harald; Espevik, Terje; Flo, Trude Helen. (2025) Intracellular and cell autonomous C3 in IRF3 signaling in macrophages. International Complement Workshop 2025
2024
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Conference posterKristensen, Stine; Årseth, Charlotte; Ryan, Liv; Lambris, John D.; Flo, Trude Helen; Mollnes, Tom Eirik; Husebye, Harald; Espevik, Terje. (2024) Decoding the intracellular complement system in human macrophages. TOLL Conference 2024
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Conference lectureCimpan, Mihaela Roxana; Rios-Mondragon, Ivan; Camassa, Laura Maria Azzurra; Puntes, Victor Franco; Skrętna, Agnieszka Gajewicz; Busquets, Marti; Longhin, Eleonora Marta; Mariussen, Espen; Hofshagen,, Ole-Bendik; Bastus, Neus Gómez. (2024) Towards a reliable assessment of nanomaterial health effects using advanced biological models and assays (NanoBioReal). NANOTOX 2024
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Conference posterNilsen, Kaja Elisabeth; Skjesol, Astrid; Bakke, Siril Skaret; Ryan, Liv; Stenvik, Jørgen; Espevik, Terje; Yurchenko, Maria. (2024) SLAMF1-derived peptide inhibits signaling initiated by endosomal Toll-like receptors. TOLL 2024
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Conference posterMestvedt, Ingvild Bergdal; Yurchenko, Maria; Espevik, Terje; Standal, Therese; Wolowczyk, Camilla Izabel; Rasheed, Kashif; Misund, Kristine; Slørdahl, Tobias Schmidt; Hella, Hanne; Ryan, Liv. (2024) Exploring peptide derived from Signaling Lymphocytic Activation Molecule Family 1 as novel treatment for multiple myeloma. ENA 2024 Symposium on molecular targets and cancer therapeutics
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Conference posterGravastrand, Caroline Saugestad; Yurchenko, Maria; Kristensen, Stine; Skjesol, A.; Espevik, Terje; Husebye, Harald. (2024) The Rab GTPase Rab11b and its effector Rab11-FIP2 are key regulators of the NLRP3 inflammasome. Cell death: Friend or foe in animal and plant immunity
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Conference posterGravastrand, Caroline Saugestad; Yurchenko, Maria; Kristensen, Stine; Skjesol, Astrid; Espevik, Terje; Husebye, Harald. (2024) The Rab11-family interacting protein 2 is a key regulator of the NLRP3 inflammasome. Poster
2023
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Conference posterNilsen, Kaja Elisabeth; Zhang, Boyao; Skjesol, Astrid; Bakke, Siril Skaret; Gravastrand, Caroline Saugestad; Ryan, Liv; Mestdvedt, Ingvild Bergdal; Husebye, Harald; Lien, Egil; Espevik, Terje. (2023) SLAMF1-derived peptide could limit the inflammation mediated by several Toll-like receptors. 18th International Conference on Innate Immunity
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Conference lectureNilsen, Asbjørn Magne; Espevik, Terje. (2023) Human whole blood: Model for toxicity assessment?. Workshop on: New Approach Methodologies for NanoSafety. NanoBioReal, NFR project 288768
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Conference posterMestvedt, Ingvild Bergdal; Yurchenko, Maria; Misund, Kristine; Hella, Hanne; Espevik, Terje; Slørdahl, Tobias Schmidt. (2023) SLAMF1-derived peptide P7N4-Pen as anti-myeloma treatment. 20th International Myeloma Society Annual Meeting
2022
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Conference lectureEspevik, Terje. (2022) Inflammatory responses of cholesterol crystals in atherosclerotic disease. Drug discovery targeting inflammation
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Conference lecture
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Conference lectureEspevik, Terje. (2022) Inflammatory potential of cholesterol crystals in aortic disease – role of complement. 3rd International Symposium on Aortic Disease
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Conference lecture
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Conference posterHusebye, Harald; Gravastrand, Caroline Saugestad; Yurchenko, Mariya; Espevik, Terje. (2022) The Rab11-family interacting protein 2 is a regulator of the NLRP3 inflammasome. EMBO Workshop Dying in self-defense: Cell death signaling in animals and plants
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Conference lectureHusebye, Harald; Gravastrand, Caroline Saugestad; Yurchenko, Mariya; Skjesol, Astrid; Espevik, Terje. (2022) The Rab11-family interacting protein 2 is a regulator of the NLRP3 inflammasome. BNMI – Bridging the Nordic Microscopy Infrastructure
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LectureBrekke, Ole Lars; Grond, Joost; Landsem, Anne; Christiansen, Dorte; Ludviksen, Judith K; Lau, Corinna; Woodruff, T. M.; Lambris, John D.; Espevik, Terje; Mollnes, Tom Eirik. (2022) Effects of complement C3, C5 and CD14 inhibitors on bacterial survival and thromboinflammation induced by two different live E.coli-strains in human whole blood. Complement Therapeutics 2022
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Conference lectureEspevik, Terje. (2022) Activation of the complement system by cholesterol crystals. 14th International Conference on Complement Therapeutics
2021
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Conference lectureEspevik, Terje. (2021) Role of the Complement system in Inflammasome Activation mediated by Cholesterol Crystals. Keystone Symposia
2020
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Conference lectureNarverud, Ingunn; Christensen, Jacob Juel; Bakke, Siril Skaret; Ulven, Stine Marie; Rundblad, Amanda; Aukrust, Pål; Espevik, Terje; Bogsrud, Martin Prøven; Retterstøl, Kjetil; Ueland, Thor. (2020) Profiling of immune‐related gene expression in children with familial hypercholesterolaemia. Throne-Holst Stiftelse Festaften
2019
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Conference posterStenvik, Jørgen; Ehrnstrøm, Birgitta; Kojen, June Frengen; Moen, Siv Helen; Beckwith, Kai Sandvold; Giambelluca, Miriam; Afset, Jan Egil; Damås, Jan Kristian; Hu, Zhenyi; Yin, Hang. (2019) TLR8 is a central bacterial sensor in human monocytes. International Conference on Molecular Mechanisms of Inflammation
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Interview
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Conference posterEhrnstrøm, Birgitta; Kojen, June Frengen; Moen, Siv Helen; Damås, Jan Kristian; Mollnes, Tom Eirik; Hu, Zhenyi; Yin, Hang; Espevik, Terje; Stenvik, Jørgen. (2019) Toll-like receptor 8 senses bacteria in human whole blood. International conference on molecular mechanisms of inflammation
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Conference posterMoen, Siv Helen; Kojen, June Frengen; Yurchenko, Mariya; Ehrnstrøm, Birgitta; Damås, Jan Kristian; Espevik, Terje; Stenvik, Jørgen. (2019) Cell surface TLRs antagonize TLR8 signaling in monocytes via an IRAK-1 dependent mechanism. International conference of molecular mechanisms of inflammation
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Conference posterGravastrand, Caroline S.; Steinkjer, Bjørg; Halvorsen, Bente; Landsem, Anne; Skjelland, Mona; Jacobsen, Eva Astrid; Woodruff, Trent M.; Lambris, John D.; Mollnes, Tom Eirik; Brekke, Ole-Lars. (2019) Cholesterol crystals induce thromboinflammation. Conference on molecular mechanisms in Trondheim
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Conference posterGravastrand, Caroline S.; Skjesol, Astrid; Yurchenko, Mariya; Jakovljev, Aleksandra; Afset, Jan Egil; Espevik, Terje; Husebye, Harald. (2019) FIP2 regulates inflammatory cell death in human macrophages. Seeing is Believing - Imaging the Molecular Processes of Life
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Conference posterSkjesol, Astrid; Yurchenko, Mariya; Bösl, Korbinian; Gravastrand, Caroline S.; Nilsen, Kaja Elisabeth; Agliano, Federica; Kim, Hera; Sporsheim, Bjørnar; Teti, Giuseppe; Stenmark, Harald. (2019) The TLR4 adaptor TRAM controls phagocytosis of E. coli through FIP2. 2nd Conference on Molecular Mechanisms of Inflammation
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Conference posterGravastrand, Caroline S.; Skjesol, Astrid; Yurchenko, Mariya; Jakovljev, Aleksandra; Afset, Jan Egil; Espevik, Terje; Husebye, Harald. (2019) FIP2 regulates inflammatory cell death in macrophages. EMBO workshop, Cell death in immunity and inflammation
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Conference lectureEspevik, Terje. (2019) Cholesterol crystals use complement to increase NLRP3 signalling pathways in atherosclerosis. 12th International Conference on Complement Therapeutics
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LectureEspevik, Terje. (2019) Phagocytosis and phagocytic signaling for antibacterial defence. Invited lecture at Gøteborg University
2018
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Conference posterMoen, Siv Helen; Kojen, June Frengen; Ehrnstrøm, Birgitta; Damås, Jan Kristian; Espevik, Terje; Stenvik, Jørgen. (2018) CROSSTALK OF HUMAN TLR2 AND TLR8 SIGNALING. 2nd. International NTNU Symposium on Current and Future Clinical Biomarkers of Cancer
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Conference posterMoen, Siv Helen; Kojen, June Frengen; Ehrnstrøm, Birgitta; Damås, Jan Kristian; Espevik, Terje; Stenvik, Jørgen. (2018) CROSSTALK OF HUMAN TLR2 AND TLR8 SIGNALING. Toll 2018 Editing Innate Immunity
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Conference posterBugge, Marit; EIde, Oda Kamilla; Solli, Helene; Kjønstad, Ingrid Fadum; Stenvik, Jørgen; Bergstrøm, Bjarte; Espevik, Terje; Nilsen, Nadra. (2018) SURFACE TOLL-LIKE RECEPTOR 3 EXPRESSION IN METASTATIC INTESTINAL EPITHELIAL CELLS INDUCES INFLAMMATORY CYTOKINE PRODUCTION AND PROMOTES INVASIVENESS. Toll 2018 Translating Innate Immunity
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Conference lectureBugge, Marit; Espevik, Terje; Nilsen, Nadra. (2018) Altered Toll-Like Receptor Expression and Signaling in Colorectal Cancer Cells promotes Invasiveness. 2nd International NTNU Symposium Current and Future Clinical Biomarkers of Cancer: From diagnosis to immunotherapy – why is precision medicine so difficult?
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Conference posterEhrnström, Birgitta; Kojen, June Frengen; Moen, Siv Helen; Damås, Jan Kristian; Afset, Jan Egil; Mollnes, Tom Eirik; Hu, Zhenyi; Yin, Hang; Espevik, Terje; Stenvik, Jørgen. (2018) Toll-like Receptor 8 is a Major Bacterial Sensor in Human Monocytes and Blood. Toll 2018
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Conference posterBösl, Korbinian; Giambelluca, Miriam; Haug, Markus; Bugge, Marit; Espevik, Terje; Kandasamy, Richard Kumaran; Bergstrøm, Bjarte Aune. (2018) Coactivation of TLR2 and TLR8 in Primary Human Monocytes Triggers a Distinct Inflammatory Signaling Response. Annual Meeting Research School in Infection Biology and and Antimicrobials
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Conference posterChristensen, Jacob J.; Bakke, Siril Skaret; Ulven, Stine Marie; Retterstøl, Kjetil; Henriksen, Tore; Bollerslev, Jens; Espevik, Terje; Aukrust, Pål; Halvorsen, Bente; Holven, Kirsten Bjørklund. (2018) Association between omega 6 fatty acids and inflammation-related gene expression in PBMCs: a cross-sectional study in healthy children. Scandinavian society of atherosclerosis Research
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Conference posterStavik, Benedicte; Tinholt, Mari; Skjelland, Mona; Espevik, Terje; Sandset, Per Morten; Halvorsen, Bente; Iversen, Nina. (2018) Coagulation factors in human atherosclerotic plaques – a potential link to inflammation?. Eurothrombosis 2018
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Conference lecture
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Conference posterLunde, Ngoc Nguyen Dieu; Holm, Sverre; Dahl, Tuva Børresdatter; Elyouncha, Inass; Sporsheim, Bjørnar; Gregersen, Ida; Abbas, Azhar; Skjelland, Mona; Espevik, Terje; Solberg, Rigmor. (2018) Plasma and plaques from patients with carotid atherosclerosis have increased levels of legumain. 24th Annual Scandinavian Atherosclerosis Conference
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Conference posterLunde, Ngoc Nguyen Dieu; Gregersen, Ida; Holm, Sverre; Michelsen, Annika; Sporsheim, Bjørnar; Espevik, Terje; Solberg, Rigmor; Johansen, Harald Thidemann; Halvorsen, Bente. (2018) Platelet-derived legumain, a cysteine protease involved in atherosclerosis. Proteolytic Enzymes and Their Inhibitors Gordon Research Conference
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Conference lectureEspevik, Terje. (2018) Phagocytic signalling for antibacterial defence. Toll2018 Editing Innate Immunity
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Conference lectureEspevik, Terje. (2018) Phagocytosis of Gram-negative bacteria requires the Toll-like receptor 4 adapter TRAM. 15th International Conference on Innate Immunity
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Conference posterYurchenko, Mariya; Skjesol, Astrid; Husebye, Harald; Espevik, Terje. (2018) SLAMF1 regulates signaling via TLR4 and bacterial killing in human macrophages. Toll 2018. Editing Innate Immunity
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Conference posterSkjesol, Astrid; Yurchenko, Mariya; Espevik, Terje; Husebye, Harald. (2018) The TLR4 adaptor TRAM controls phagocytosis of Gram-negative bacteria through TRAM and the Rab11-family interacting protein 2. Toll 2018, Editing Innate Immunity
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Conference lectureRokstad, Anne Mari; Gravastrand, Caroline S.; Halvorsen, Bente; Steinkjer, Bjørg; Skjelland, Mona; Jacobsen, Eva Astrid; Lambris, John D.; Mollnes, Tom Eirik; Brekke, Ole-Lars; Espevik, Terje. (2018) Cholesterol crystals induce coagulation that can be prevented by targeting complement. 11th International Conference on Complement Therapeutics
2017
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Conference posterBugge, Marit; Bergstrøm, Bjarte Aune; Eide, Oda K.; Solli, Helene; Kjønstad, Ingrid Fadum; Stenvik, Jørgen; Espevik, Terje; Nilsen, Nadra. (2017) Surface Toll-Like Receptor 3 Expression in Metastatic Intestinal Epithelial Cells induces Inflammatory Cytokine Production and Promotes Invasiveness. Development of Tissue- and Pathogen-specific Cellular Innate Immunity
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Conference posterSkjesol, Astrid; Yurchenko, Mariya; Espevik, Terje; Husebye, Harald. (2017) The TLR4 adaptor TRAM controls phagocytosis of Gram-negative bacteria through interaction with the Rab11-family interacting protein 2. Type I Interferon: Friend and Foe Alike (X6)
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Conference posterSkjesol, Astrid; Husebye, Harald; Yurchenko, Mariya; Egeberg, Kjartan Wøllo; Espevik, Terje. (2017) The TLR4 adaptor TRAM controls phagocytosis of Gram-negative bacteria. Seeing is Believing
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Conference posterBakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Pilely, Katrine; Ryan, Liv; Skjelland, Mona; Garred, Peter; Aukrust, Pål; Halvorsen, Bente; Latz, Eicke. (2017) Cyclodextrin inhibits CC-induced complement activation. the 16th European Meeting on Complement in Human Disease
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Conference lectureHusebye, Harald; Skjesol, Astrid; Yurchenko, Mariya; Grøvdal, Lene Melsæther; Bösl, Korbinian; Agliano, Federica; Patane, Francesco; Lentini, Germana; Kim, Hera; Kandasamy, Richard Kumaran. (2017) The TLR4 adaptor TRAM controls phagocytosis of Gram-negative bacteria through the Rab11-family interacting protein 2. Cemir retreat
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Conference posterLunde, Ngoc Nguyen Dieu; Holm, Sverre; Dahl, Tuva B.; Elyoncha, Inass; Sporsheim, Bjørnar; Gregersen, Ida; Abbas, Azhar; Skjelland, Mona; Espevik, Terje; Solberg, Rigmor. (2017) Plasma and plaques from patients with carotid atherosclerosis have increased levels of legumain. 10th General Meeting of the International Proteolysis Society (IPS)
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LectureEspevik, Terje; Niyonzima, Nathalie; Bakke, Siril Skaret; Halvorsen, Bente; Gregersen, Ida; Skjelland, Mona; Yndestad, Arne; Sandanger, Øystein; Andersen, Geir Øystein; Gullestad, Lars. (2017) Systemic- and local complement activation controls the NLRP3 inflammasome pathway in patients with atherosclerosis. Lecture
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Conference posterSkjesol, Astrid; Sporsheim, Bjørnar; Yurchenko, Mariya; Egeberg, Kjartan Wøllo; Espevik, Terje; Husebye, Harald. (2017) The TLR4 adaptor TRAM controls phagocytosis of Gram-negative bacteria. 17th International European Light Microscopy Initiative Meeting
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LectureNiyonzima, Nathalie; Freeley, Simon; Arbore, Giuseppina; Friec, Gaelle Le; Lappegaard, Knut Tore; Mollnes, Tom Eirik; Kemper, Claudia; Espevik, Terje. (2017) The intracellular C5 system is critical to DAMP sensing and cellular responses in human monocytes. Lecture
2016
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Conference posterStavik, Benedicte; Espada, Sandra; Holm, Sverre; Bjerkeli, Vigdis; Sandset, Per Morten; Dahl, Tuva Børresdatter; Skjelland, Mona; Espevik, Terje; Iversen, Nina; Skretting, Grethe. (2016) Cholesterol crystals induce TFPI expression in alternatively activated human monocyte-derived macrophages. Conference on Molecular Mechanisms of Inflammation
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Conference posterYurchenko, Mariya; Skjesol, Astrid; Husebye, Harald; Espevik, Terje. (2016) CD150 positively regulates TRAM recruitment to E. coli phagosomes and TLR4-induced IFNbeta production. Conference on Molecular Mechanisms of Inflammation
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LectureYurchenko, Mariya; Skjesol, Astrid; Husebye, Harald; Espevik, Terje. (2016) CD150 positively regulates TRAM recruitment to E.coli phagosomes and type I IFN secretion. Cell symposium - 100 years of phagocytes
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Conference posterGrøvdal, Lene Melsæther; Schink, Kay Oliver; Pelka, Karin; Husebye, Harald; Latz, Eicke; Stenmark, Harald Alfred; Espevik, Terje. (2016) Moving Tolls - Novel interactors of TLR9 trafficking. CEMIR Conference 2016
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Conference posterBakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Ryan, Liv; Pilely, Katrine; Garred, Peter; Damås, Jan Kristian; Latz, Eicke; Mollnes, Tom Eirik; Espevik, Terje. (2016) β- CYCLODEXTRIN REDUCES CHOLESTEROL CRYSTAL-INDUCED INFLAMMATION THROUGH MODULATING COMPLEMENT ACTIVATION. Conference on Molecular Mechanisms of Inflammation
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Conference posterGravastrand, Caroline; Steinkjer, Bjørg; Fure, Hilde; Ryan, Liv; Martins, Catia; Mollnes, Tom Eirik; Brekke, Ole Lars; Espevik, Terje; Rokstad, Anne Mari. (2016) Cholesterol crystals induce coagulation activation in a complement-dependent manner. Conference on Molecular Mechanisms of Inflammation
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Conference lectureStavik, Benedicte; Holm, Sverre; Espada, Sandra; Iversen, Nina; Sporsheim, Bjørnar; Bjerkeli, Vigdis; Dahl, Tuva Børresdatter; Sandset, Per Morten; Skjelland, Mona; Espevik, Terje. (2016) Unconventional mechanisms of targeting atherosclerosis. The 49th Nordic Coagulation Meeting
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Conference posterGrøvdal, Lene Melsæther; Schink, Kay Oliver; Pelka, Karin; Husebye, Harald; Latz, Eicke; Stenmark, Harald Alfred; Espevik, Terje. (2016) Moving Tolls - novel interactors of TLR9 trafficking. NBS contact meeting 2016
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Conference posterGravastrand, Caroline; Teigen, Ellen; Vorkinn, Ingvild; Steinkjer, Bjørg; Gierman, Lobke; Nymo, Siren; Kulseng, Bård Eirik; Martins, Catia; Espevik, Terje; Rokstad, Anne Mari. (2016) Effect of rapid weight loss in obese individuals with focus on inflammatory receptor expression in peripheral blood leukocytes. Conference on Molecular Mechanisms of Inflammation
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Conference posterEspada Serrano, Sandra; Holm, Sverre; Bjerkeli, Vigdis; Skjelland, Mona; Dahl, Tuva Børresdatter; Iversen, Nina; Espevik, Terje; Sandset, Per Morten; Skretting, Grethe; Halvorsen, Bente. (2016) ER stress conditions lead to an upregulation of TFPI and is associated with an anti-apoptotic macrophage phenotype. 22nd ANNUAL SCANDINAVIAN ATHEROSCLEROSIS CONFERENCE
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Conference posterEgeberg, Kjartan Wøllo; Sporsheim, Bjørnar; Espevik, Terje. (2016) STED microscopy of ASC speck inflammasome formation in mouse macrophages. Biokjemisk kontaktmøte 2016
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Conference posterGravastrand, Caroline; Steinkjer, Bjørg; Fure, Hilde; Niyonzima, Nathalie; Lambris, John D.; Mollnes, Tom Eirik; Brekke, Ole-Lars; Espevik, Terje; Rokstad, Anne Mari. (2016) Cholesterol crystals induce coagulation activation in a complement-dependent manner. 2nd International Conference on Immune Responses to Biosurfaces: Mechanisms and Therapeutic Interventions
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Conference lectureStenvik, Jørgen; Bergstrøm, Bjarte; Aune, Marie Hjelmseth; Awuh, Jane Atesoh; Kojen, June Frengen; Blix, Kjetil Jordahl; Ryan, Liv; Flo, Trude Helen; Mollnes, Tom Eirik; Espevik, Terje. (2016) TLR8 Senses Staphylococcus aureus RNA in Human Primary Monocytes and Macrophages and Induces IFN-b Production via a TAK1–IKKb–IRF5 Signaling Pathway. International Conference on Molecular Mechanisms of Inflammation
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Conference posterChristiansen, Dorte; Skjeflo, Espen Waage; Landsem, Anne; Mathisen, Monica Dammen; Fure, Hilde; Stenvik, Jørgen; Woodruff, Trent; Espevik, Terje; Mollnes, Tom Eirik. (2016) The effect of combined inhibition of C5aR1 and CD14 on phagocytosis of E. coli in human whole blood. The XXVI International Complement Workshop (ICW)
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Conference posterSkjesol, Astrid; Yurchenko, Mariya; Agliano, Federica; Patane, Francesco; Teti, Guiseppe; McCaffrey, Mary; Espevik, Terje; Husebye, Harald. (2016) Rab11-family interacting protein 2 (FIP2) mediates phagocytosis of E.coli. Cell symposium - 100 years of phagocytes
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Conference lectureNiyonzima, Nathalie; Freeley, Simon; Arbore, Giuseppina; Friec, Gaelle Le; Lappegård, Knut Tore; Mollnes, Tom Eirik; Kemper, Claudia; Espevik, Terje. (2016) The intracellular C5 system is critical to DAMP sensing and cellular responses in human monocytes. XXVI th International Complement Workshop
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Conference posterSkjesol, Astrid; Yurchenko, Mariya; Agliano, Federica; Patane, Francesco; Teti, Guiseppe; McCaffrey, Mary; Espevik, Terje; Husebye, Harald. (2016) Rab11-family interacting protein 2 mediates phagocytosis of E.coli. Conference on Molecular Mechanisms of Inflammation
2015
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Conference posterBakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Ryan, Liv; Damås, Jan Kristian; Mollnes, Tom Eirik; Latz, Eicke; Espevik, Terje. (2015) Beta-cyclodextrin reduces cholesterol crystal-induced inflammation through modulating complement activation. European Meeting on Complement in Human Disease
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Conference posterAune, Marie Hjelmseth; Niyonzima, Nathalie; Samstad, Eivind; Bakke, Siril Skaret; Ryan, Liv; Rokstad, Anne Mari; Nymo, Stig Haugset; Damås, Jan Kristian; Latz, Eicke; Mollnes, Tom Eirik. (2015) Crystalline cholesterol is found in atherosclerotic plaques and induces complement mediated inflammation. 15th European Meeting on Complement in Human Disease
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Conference posterSporsheim, Bjørnar; Egeberg, Kjartan Wøllo; Klein, Dionne; Espevik, Terje. (2015) STED microscopy at the Cellular and Molecular Imaging Core facility. NBS kontaktmøte
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Conference lectureBergstrøm, Bjarte; Aune, Marie Hjelmseth; Awuh, Jane Atesoh; Kojen, June Frengen; Ryan, Liv; Flo, Trude Helen; Mollnes, Tom Eirik; Stenvik, Jørgen; Espevik, Terje. (2015) TLR8 is a sensor for Staphylococcus aureus RNA in human monocytes and macrophages. 12th International Conference on Innate Immunity
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Conference posterSkjesol, Astrid; Patane, Francesco; Yurchenko, Mariya; Aune, Marie Hjelmseth; McCaffrey, Mary; Espevik, Terje; Husebye, Harald. (2015) The small GTPase Rab11a and its partner Rab11FIP2 affect TLR4 signaling pathways. TOLL 2015 Targeting innate immunity
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Conference posterSkjesol, Astrid; Patane, Francesco; Yurchenko, Mariya; Aune, Marie Hjelmseth; McCaffrey, Mary; Espevik, Terje; Husebye, Harald. (2015) The small GTPase Rab11a and its partner Rab11FIP2 regulate TLR4 signaling pathways. 15th annual meeting of the European Light Microscopy Initiative (ELMI)
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Conference lectureArlov, Øystein; Aachmann, Finn L.; Sundan, Anders; Espevik, Terje; Skjåk-Bræk, Gudmund. (2015) Heparin Analogs from Sulfated Alginates. 8th European Symposium on Bioploymers
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Conference posterNilsen, Nadra J.; Espevik, Terje; Vladimer, G; Stenvik, Jørgen; Orning, M. Pontus A.; Zeid-Kilani, Maria Vanessa; Bugge, Marit; Bergstrøm, Bjarte; Conlon, Joseph; Husebye, Harald. (2015) THE ADAPTOR PROTEINS TRAM AND TRIF MEDIATE TOLL-LIKE RECEPTOR 2 SIGNALING. Innate Immune Memory
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Conference posterNilsen, Nadra J.; Espevik, Terje; Gjerdingen, Thea Johannne; Bugge, Marit; Kjønstad, Ingrid Fadum. (2015) A TOLL-LIKE RECEPTOR 7/8 LIGAND SECRETED BY MYELOMA CELLS INDUCES PRIMARY BONE MARROW STROMAL CELLS TO PRODUCE CYTOKINES THAT PROMOTE MYELOMA SURVIVAL. Toll2015 Targeting Innate Immunity
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LectureNilsen, Nadra J.; Espevik, Terje; Vladimer, G; Ørning, Mathias Pontus; Zeid-Kilani, Maria Vanessa; Bugge, Marit; Bergstrøm, Bjarte; Conlon, Joseph; Husebye, Harald; Hise, Amy G. (2015) THE ADAPTOR PROTEINS TRAM AND TRIF MEDIATE TOLL-LIKE RECEPTOR 2 SIGNALING. Toll2015 Targeting Innate Immunity
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Conference posterYurchenko, Mariya; Skjesol, Astrid; Husebye, Harald; Espevik, Terje. (2015) CD150 REGULATES TYPE I IFN PRODUCTION FROM E.COLI PHAGOSOMES BY AFFECTING TRAM TRAFFICKING. Toll Conference 2015 Targeting Innate Immunity
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Conference posterBergstrøm, Bjarte; Ryan, Liv; Espevik, Terje; Stenvik, Jørgen. (2015) Emerging behaviour in multi-PRR signaling. TOLL 2015
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Conference posterSporsheim, Bjørnar; Egeberg, Kjartan Wøllo; Espevik, Terje. (2015) STED microscopy of ASC speck inflammasome formation in mouse macrophages. 15th International ELMI meeting
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Conference posterGrøvdal, Lene Melsæther; Schink, Kay Oliver; Pelka, Karin; Husebye, Harald; Latz, Eicke; Stenmark, Harald Alfred; Espevik, Terje. (2015) Moving Tolls - novel interactors of TLR9 trafficking. Seeing is Believing - Imaging the Processes of Life.
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Conference posterGrøvdal, Lene Melsæther; Schink, Kay Oliver; Pelka, Karin; Husebye, Harald; Latz, Eicke; Stenmark, Harald Alfred; Espevik, Terje. (2015) Moving Tolls - novel interactors of TLR9 trafficking. The multidisciplinary era of endocytic mechanics and functions
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LectureAune, Marie Hjelmseth; Niyonzima, Nathalie; Samstad, Eivind; Nymo, Stig; Ryan, Liv; Bakke, Siril Skaret; Damås, Jan Kristian; Latz, Eicke; Mollnes, Tom Eirik; Espevik, Terje. (2015) Cholesterol crystals activate the complement system to induce crystal phagocytosis and inflammation. 17TH International Congress on Atherosclerosis 2015
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Conference posterBugge, Marit; Solli, Helene; Kjønstad, Ingrid F.; Stenvik, Jørgen; Espevik, Terje; Nilsen, Nadra J.. (2015) Metastatic Intestinal Epithelial Cells Express Surface Toll-Like Receptor 3. Toll 2015 Targeting Innate Immunity
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Conference posterBakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Ryan, Liv; Damås, Jan Kristian; Latz, Eicke; Mollnes, Tom Eirik; Espevik, Terje. (2015) β- CYCLODEXTRIN REDUCES CHOLESTEROL CRYSTAL-INDUCED INFLAMMATION THROUGH MODULATING COMPLEMENT ACTIVATION. Toll 2015
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Conference posterEgeberg, Kjartan Wøllo; Sporsheim, Bjørnar; Espevik, Terje. (2015) STED microscopy of ASC speck inflammasome formation in mouse macrophages. EMBL Symposium "Seeing is Believing"
2014
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LectureAune, Marie Hjelmseth; Samstad, Eivind; Niyonzima, Nathalie; Nymo, Stig Haugset; Ryan, Liv; Lappegård, Knut Tore; Brekke, Ole Lars; Lambris, John D.; Damås, Jan Kristian; Latz, Eicke. (2014) Cholesterol crystals induce complement-dependent inflammasome activation. NBS Contact Meeting
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Conference lectureØstvik, Ann Elisabet; Granlund, Atle Van Beelen; Gustafsson, Bjørn I; Espevik, Terje; Damås, Jan Kristian; Mollnes, Tom Eirik; Sandvik, Arne. (2014) Lokal Toll-reseptor 3-avhengig syntese av komplement faktor B og lokal komplement aktivering ved inflammatorisk tarmsykdom. 41. årsmøte. Norsk gastroenterologis forening
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Conference posterØstvik, Ann Elisabet; Granlund, Atle Van Beelen; Damås, Jan Kristian; Gustafsson, Björn; Torp, Sverre Helge; Espevik, Terje; Mollnes, Tom Eirik; Sandvik, Arne Kristian. (2014) Epithelial Toll-like receptor 3-dependent synthesis of complement factor B and local complement activation in inflammatory bowel disease. 9th Congress of ECCO
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Conference posterSkjesol, Astrid; McCaffrey, Mary; Espevik, Terje; Husebye, Harald. (2014) Involvement of Rab11-FIPs (Rab11-family interacting proteins) in TRAM trafficking. NBS Vintermøte 2014
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Conference posterEgeberg, Kjartan Wøllo; Klein, Dionne C.G.; Espevik, Terje. (2014) Cellular and Molecular Imaging Core Facility (CMIC). ELMI 2014
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Conference posterSkjesol, Astrid; McCaffrey, Mary; Espevik, Terje; Husebye, Harald. (2014) Involvement of Rab11FIP2 in TRAM trafficking. European Light Microscopy Initiative
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LectureRokstad, Anne Mari; Ørning, Mathias Pontus; Hamad, Shamal; Hoem, Kine Samseth; Steinkjer, Bjørg; Fure, Hilde; Ryan, Liv; Lacík, Igor; Mollnes, Tom Eirik; Brekke, Ole Lars. (2014) Inflammatory and hemostatic activation induced by alginate microcapsules reveals novel mechanisms underlying their biocompatibility. Immune responces to biosurfaces: Mechanisms and therapeutic interventions
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LectureRokstad, Anne Mari; Hamad, Shamal; Steinkjer, Bjørg; Fure, Hilde; Niyonzima, Nathalie; Ørning, Mathias Pontus; Lacík, Igor; Ryan, Liv; Mollnes, Tom Eirik; Espevik, Terje. (2014) Initial inflammatory and haemostatic mechanisms induced by endogenous and bioartificial surfaces in a whole blood model. NBS contact Meeting 2014
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Conference posterKlein, Dionne; Kers-Rebel, Esther; Espevik, Terje; Husebye, Harald. (2014) The adaptor protein TRAM and LPS-bound CD14 show different trafficking behavior in the MyD88-independent pathway. 14th International Advanced Light Microscopy Meeting
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Conference lectureEspevik, Terje. (2014) Cholesterol crystals induce inflammation: how does it happen and why does it matter?. Research Institute of Internal Medicine seminar
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Conference lectureEspevik, Terje. (2014) Toll-like receptor 4 signalling from the endosome. Europeat Tissues Repair Society meeting
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Conference lecture
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Conference lectureEspevik, Terje. (2014) Inflammatory responses induced by cholesterol crystals. 11th International Conference on Innate Immunity
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Conference lectureEspevik, Terje. (2014) TLR4/TRAM trafficking mechanisms involved in the IFN-β response induced by E.coli. Seminar
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Conference lectureEspevik, Terje. (2014) Mechanisms involved in the induction of IFN-β by Gram negative- and Gram positive bacteria. Seminar
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LectureKlein, Dionne; Kers-Rebel, Esther; Espevik, Terje; Husebye, Harald. (2014) The signal adaptor protein TRAM and CD14/LPS show different kinetics on endosomes during LPS induced TLR4 signaling. Norwegian Biochemical Society Meeting
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Conference posterKlein, Dionne; Egeberg, Kjartan Wøllo; Espevik, Terje. (2014) Cellular and Molecular Imaging Core Facility (CMIC). Norwegian Biochemical Society Meeting
2013
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Conference lectureAune, Marie Hjelmseth; Samstad, Eivind; Niyonzima, Nathalie; Nymo, Stig; Ryan, Liv; Lappegård, Knut Tore; Brekke, Ole-Lars; Lambris, John D.; Damås, Jan Kristian; Latz, Eicke. (2013) Cholesterol crystals induce complement-dependent inflammasome activation. Inflammasomes in health and disease
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Interview
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Interview
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Interview
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Conference posterSkjesol, Astrid; Starheim, Kristian Kobbenes; Klein, Dionne C.G.; McCaffrey, Mary; Espevik, Terje; Husebye, Harald. (2013) The small GTPase Rab11a integrates TRAM trafficking between TGN and endosome in LPS induced TRAM-TRIF-signaling. Systems Dynamics in Endocytosis
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Conference posterKlein, Dionne; Espevik, Terje. (2013) Cellular and Molecular Imaging Core Facility (CMIC). The Annual Meeting of the Nordic Microscopy Society SCANDEM 2013
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LectureKlein, Dionne; Kers, Esther; Espevik, Terje; Husebye, Harald. (2013) Dynamics of toll-like receptor 4 and its adaptor protein TRAM. The Annual Meeting of the Nordic Microscopy Society SCANDEM 2013
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Conference lectureEspevik, Terje. (2013) Toll-like receptor signalling in innate and adaptive immunity. PhD kurs: Mechanisms of cellular signal transduction, Universitetet i Oslo
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LectureEspevik, Terje. (2013) CEMIR - a new centre of excellence on inflammation research. CEMIR opening seminar, NTNU
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LectureEspevik, Terje. (2013) CEMIR - Centre of Molecular Inflammation Research. Offisiell åpning av de 4 nye SFF sentrene ved NTNU
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Lecture
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Lecture
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Conference lectureEspevik, Terje. (2013) Cholesterol crystal-mediated inflammation: relationship to development of atherosclerosis. 6th International Conference on Complement Therapeutics
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Conference lectureEspevik, Terje. (2013) Introduction to Innate Immunity. PhD course Innate Immunity, University of Copenhagen
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Conference lectureEspevik, Terje. (2013) Complement dependency of cholesterol crystal induced inflammation. Gjesteforelesning ved University of Massachusetts
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Conference lectureEspevik, Terje. (2013) Involvement of cholesterol crystals in atherosclerosis. Gjesteforelesning ved Boston University
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Conference lectureEspevik, Terje. (2013) Staphylococcus aureus triggers IFN-beta induction in human monocytes by phagosomal TLR8 signaling. 10th International Conference on Innate Immunity
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Conference lectureEspevik, Terje. (2013) TLRs, NLRs, PAMPs and DAMPS in innate immunity. PhD course Innate Immunity, University of Copenhagen
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Conference lectureEspevik, Terje. (2013) Kolesterolkrystaller som årsak til inflammasjon ved aterosklerose. Åpning av Jebsen senter, Universitetet i Oslo
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Lecture
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Conference posterBugge, Marit; Nilsen, Nadra; Espevik, Terje. (2013) A potential role for TLR3 expression and TLR3 mediated responses in the progression of colorectal cancer. Keystone Symposia on Cancer Immunology and Immunotherapy
2012
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Conference lectureKlein, Dionne; Egeberg, Kjartan Wøllo; Espevik, Terje. (2012) Cellular and Molecular Imaging Core Facility (CMIC). 5th NorMIC Meeting
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Conference lectureKlein, Dionne; Kers-Rebel, Esther; Espevik, Terje; Husebye, Harald. (2012) Dynamics of Toll-like receptor 4 and its adaptor protein TRAM. Instituttseminar
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Conference posterRokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Lambris, John D.; Lacík, Igor; Mollnes, Tom Eirik; Espevik, Terje. (2012) Poly-cation containing alginate microcapsules induce cytokines by a complement-dependent mechanism. XXIV. International Complement Workshop
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Conference lectureKlein, Dionne; Kers-Rebel, Esther; Espevik, Terje; Husebye, Harald. (2012) FRAP study of TLR4 dynamics. 5th NorMIC Meeting
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Conference posterØstvik, Ann Elisabet; Granlund, Atle; Torp, Sverre Helge; Flatberg, Arnar; Waldum, Helge; Espevik, Terje; Damås, Jan Kristian; Sandvik, Arne Kristian. (2012) Induction of Lipocalin-2 in colonic epithelial cells in inflammatory bowel disease. 2012 Advances in Inflammatory Bowel Disease Cohn`s and Colitis Fundation`s National Clinical & Research Conference
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Conference lectureHusebye, Harald; Espevik, Terje. (2012) Mechanisms behind toll-like receptor 4 (TLR4) signaling. Winter school 2012 on innate immunity and synthetic biology
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Conference posterKlein, Dionne; Oestvang, Janne; Espevik, Terje. (2012) Cellular and Molecular Imaging Core Facility (CMIC). Regional forskningskonferanse 2012 i Helse Midt-Norge
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Conference lectureHusebye, Harald; Espevik, terje. (2012) Mechanisms behind TLR4 induced IFN-β signaling. 5th NorMIC Meeting.
2011
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Conference posterKlein, Dionne; Rebel, Esther; Espevik, Terje; Husebye, Harald. (2011) Dynamics of Toll-like receptor 4 and its adaptor protein TRAM. NorMIC Annual Meeting
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Conference posterHusebye, Harald; Aune, Marie Hjelmseth; Steinvik, Jørgen; Espevik, Terje. (2011) The small GTPase Rab11a is involved in LPS induced IFN-β production. Deconding Innate Immunity, Riva del Garda, Italy, May 4-7, 2011
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Conference posterHusebye, Harald; Aune, Marie Hjelmseth; Stenvik, Jørgen; Espevik, Terje. (2011) The small GTPase Rab11a is involved in LPS induced IFN-β production. ISB retreat,
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Conference lectureRokstad, Anne Mari; Ryan, Liv; Steinkjer, Bjørg; Brekke, Ole Lars; Qi, Meirigeng; Oberholzer, José; Strand, Berit Løkensgard; Skjåk-Bræk, Gudmund; Lacík, Igor; Mollnes, Tom Erik. (2011) Inflammatory responses of alginate microspehers evaluated by a human and baboon whole blood model. 13th world Congress of IPITA International Pancreas and Islets Transplant Association
2010
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Conference lectureNilsen, Nadra; Espevik, Terje; Lien, Egil. (2010) The Adaptor Proteins TRAM and TRIF mediate Toll-Like Receptor 2- induced RANTES/CCL5 Release. 14th International Congress of Immunology
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Conference posterSandanger, Øystein; Ranheim, T; Ving, L R; Florholmen, Geir; Christensen, Geir Arve; Dahl, Christen Peder; Askevold, E; Finsen, Alexandra; Rashidi, A; Espevik, T. (2010) Identification and characterization of the NLRP3 inflammasome in cardiac fibroblasts. 8th Annual Center for Heart Failure Research Symposium
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Conference posterSalvesen, Bodil; Stenvik, Jørgen; Rossetti, Carlo; Saugstad, Ola Didrik; Espevik, Terje; Mollnes, Tom Eirik. (2010) Meconium-Induced Release of Cytokines, Chemokines and Growth Facteors is Mediated by the TRL4/MD-2 Complex in a CD14-Dependent Manner. Pediatric Academic Societies Annual Meeting
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Conference lectureFlo, Trude Helen; Awuh, Jane Atesoh; Halaas, Øyvind; Steigedal, Magnus; Cangelosi, Gerard; Ryan, Liv; Espevik, Terje; Husebye, Harald; Strong, Roland; Haug, Markus. (2010) Intracellular mycobacterium avium intersect transferrin in the Rab11+recycling endocytotic pathway and avoid lipocalin 2 trafficking the lysosomal pathway. NBS kontaktmøte 2010
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Conference lectureAnthonsen, Marit Walbye; Johnsen, Ingvild Bjellmo; nguyen, thuy than; Bergstrøm, Bjarte Aune; Espevik, Terje. (2010) Roles of the tyrosine kinase c-Src in innate immune responses. Mechanisms of innate antiviral immunity
2009
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Conference lectureEspevik, Terje. (2009) Regulation of TLR4 trafficking and signaling. Seminar ved Institutt for Immunologi
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Conference lectureEspevik, Terje. (2009) The Rab11a GTPase regulates trafficking of TLR4 to phagosomes containing E. Coli. 6th International Innate Immunity Conference
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Conference lectureEspevik, Terje. (2009) The endosomal pathway and innate immunity. The Endocytic Pathway in Health and Disease
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Conference lectureAune, Marie Hjelmseth; Husebye, Harald; Halaas, Øyvind; Samstad, Eivind; Latz, Eicke; Stenmark, Harald; Espevik, Terje. (2009) Rab11a controls TLR4 recruitment to Escherichia coli containing phagosomes in human monocytes. NBS, kontaktmøtet 2009
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Conference lectureKlein, Dionne; Øvrebø, Kirsti Marie; Latz, Eicke; Stokke, Bjørn Torger; Espevik, Terje. (2009) Immunostimulatory CpG DNA studied by atomic force microscopy and fluorescence correlation spectroscopy. 2nd annual NorMIC meeting
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Conference lectureAune, Marie Hjelmseth; Husebye, Harald; Espevik, Terje. (2009) Trafficking of TLR4 in human monocytes upon activation by Escherichia coli. The endocytic pathway in health and disease
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Conference posterHalaas, Ø.; Steigedal, Magnus; Haug, Markus; Awuh, Jane Atesoh; Husebye, Harald; Ryan, Liv; Espevik, Terje; Flo, Trude Helen. (2009) Intracellular Mycobacterium avium Enters the Rab11+ Recycling End¬ocytic Pathway to Access Transferrin and Escape from Lcn2 trafficking the Lysosomal Pathway. ASM General Meeting
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Conference lecture
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Conference posterAwuh, Jane Atesoh; Halaas, Øyvind; Haug, Markus; Flo, Trude Helen; Steigedal, Magnus; Brech, Andreas; Akira, Shizuo; Strong, Roland; Espevik, Terje; Ryan, Liv. (2009) Intracellular Mycobacterium avium enters the Rab11+ Recycling Endocytic Pathway to Access Transferrin and Escape from Lcn2 trafficking the Lysosomal Pathway. 4th Conference on Global Health and Vaccination Research (GlobVac)
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Conference lectureEspevik, Terje. (2009) Inflammatory responses. Invited lecture at Department of biotechnology National Institute of Chemistry
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Conference lectureEspevik, Terje. (2009) Inflammatory responses against Gram negative bacteria. Norsk Biokjemisk Selskaps Kontaktmøte
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Conference posterKlein, Dionne; Øvrebø, Kirsti Marie; Latz, Eicke; Espevik, Terje; Stokke, Bjørn Torger. (2009) Immunostimulatory CpG-DNA and its interaction with Toll-like receptor 9 investigated by AFM. International Scanning Probe Microscopy Conference
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Conference posterKlein, Dionne; Latz, Eicke; Stokke, Bjørn Torger; Espevik, Terje. (2009) Immunostimulatory CpG-DNA studied by AFM and FCS. 12th Carl Zeiss sponsored workshop on FCS and related methods
2008
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Conference lectureEspevik, Terje. (2008) Membrantrafikkering i relasjon til immunreaksjoner - nytt FUGE prosjekt. Tirsdagsmøte for DMF, NTNU og St. Olavs Hospital
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Conference posterIversen, Ann-Charlotte; Steinkjer, Bjørg; Nilsen, Nadra; Bohnhorst, Janne Øvrebø; Moen, Siv Helen; Vik, Randi; Stephens, Phil; Thomas, David W.; Benedict, Chris A.; Espevik, Terje. (2008) A proviral role for CpG in cytomegalovirus infection. Toll 2008 Conference
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Conference posterFlo, Trude Helen; Halaas, Øyvind; Steigedal, Magnus; Espevik, Terje; Ryan, Liv; Strong, Roland; Cangelosi, Gerard; Brech, Andreas; Kaiser, Bret. (2008) Lipocalin 2 protects against mycobacterial infections during the acute phase, but not in long term chronic infections. Keystone Symposia on Innate Immunity: Signaling Mechanisms
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Conference posterKlein, Dionne C.G.; Øvrebø, Kirsti Marie; Latz, Eicke; Espevik, Terje; Stokke, Bjørn Torger. (2008) Toll-like receptor 9 and its ligand CpG-DNA studied with atomic force microscopy. Normic National User Meeting NTNU
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Conference posterSkjærvold, Nils Kristian; Tyvold, Stig Sverre; Grønbech, Jon Erik; Espevik, Terje; Aadahl, Petter; Solligård, Erik. (2008) Detection of cytokines in the intestinal lumen by microdialysis. Annual Congress of The European Society of Intensive Care Medicine
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Conference posterRokstad, Anne Mari; Steinkjer, Bjørg; Lien, Egil; Espevik, Terje. (2008) TOLL like receptor 4 is involved in inflammatory reactions (overgrowth) against alginate capsules. TOLL2008 Meeting; Recent advances in Pattern recognition
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Conference posterSteigedal, Magnus; Flo, Trude Helen; Halaas, Øyvind; Ryan, Liv; Espevik, Terje. (2008) Mycobacteria are Lipocalin 2-sensitive but evade long term growth suppression by excluding lipocalin 2 from their intracellular compartment. ASM General Meeting
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Conference posterNilsen, Nadra; Deininger, Susanne; Nonstad, Unni; Skjeldal, Frode; Husebye, Harald; Rodionov, Dmitrii; Aulock, Sonja von; Hartung, Thomas; Lien, Egil; Bakke, Oddmund. (2008) Toll-like receptor 2 signaling occurs preferentially at the plasma membrane, independent of internalization, and is facilitated by both CD36 and CD14. TOLL2008
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Conference lectureHusebye, Harald; Hjelmseth, M; Samstad, Eivind Ottersen; Halaas, Øyvind; Latz, Eicke; Stenmark, Harald; Espevik, Terje. (2008) Role of Rab11 in signalling and intracellular trafficking of Toll-like receptor 4. Toll2008
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Conference lectureSteigedal, Magnus; Flo, Trude Helen; Espevik, Terje; Rognstad, Øyvind Bakken. (2008) Lipocalin 2- a novel innate immunity protein with antimicropbial effect: Role in urinary tract infection (UTI). The Norwegian Biochemical Society 44th Contact meeting
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Conference lectureKlein, Dionne C.G.; Øvrebø, Kirsti Marie; Latz, Eicke; Espevik, Terje; Stokke, Bjørn Torger. (2008) Toll-like receptor 9 and its ligand CpG-DNA studied with AFM. Veeco Scandinavian Conference, Developments in Atomic Force Microscopy for advanced imaging techniques
2007
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Conference lectureEspevik, Terje. (2007) Membrantrafikkering i relasjon til immunreaksjoner. Tirsdagsmøte, Institutt for kreftforskning og molekylær medisin
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Conference posterBohnhorst, Janne Øvrebø; Moen, Siv H; Espevik, Terje; Sundan, Anders. (2007) Bone morphogenetic protein(BMP)-4 and BMP-6 may reduce plasma cell differentiation in B cells. Inflammation and cancer
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Conference posterKlein, Dionne C.G.; Latz, Eicke; Espevik, Terje; Stokke, Bjørn Torger. (2007) Toll-like receptor 9 and its ligand CpG-DNA studied with AFM and FCS. 6th European Biophysics Congress
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Conference posterKlein, Dionne C.G.; Latz, Eicke; Espevik, Terje; Stokke, Bjørn Torger. (2007) Toll-like receptor 9 and its ligand CpG-DNA studied with AFM and FCS. 9th Annual Linz Winter Workshop
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LectureHusebye, Harald; Espevik, Terje. (2007) Toll-like receptor functions involving endosomes. TOLL 2007 Congress
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Conference lectureEspevik, Terje. (2007) Signalmekanismer for Toll-lignende reseptor 4 i relasjon til sepsis. Invitert, Nordland Sykehus
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Conference lectureEspevik, Terje. (2007) Cellular trafficking of Toll-like receptors in relation to signalling. 4th International Workshop on Complement Associated Diseases, Animal Models, and Therapeutics
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Conference lectureEspevik, Terje. (2007) Intracellular trafficking and signalling of Toll-like receptors. "From innate to specific immunity"
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Conference lectureHusebye, Harald; Halaas, Øyvind; Stenmark, Harald; Tunheim, G; Sandanger, Øystein; Brech, A; Bogen, B; Latz, Eicke; Espevik, Terje. (2007) Functions associated with intracellular trafficking of Toll-like receptor 4. Poster award 3rd price. Biokjemisk kontaktmøte
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Conference posterNilsen, Asbjørn Magne; Vik, Randi; Behrens, Carl; Drabløs, Per Arne; Espevik, Terje. (2007) BERYLLIUM SENSITIVITY AMONG WORKERS AT A NORWEGIAN ALUMINIUM SMELTER. EHSARPA 2007
2006
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Conference posterJohnsen, Ingvild Bjellmo; Ringdal, Monika; Nguyen, Thank Thuy Thi; Tryggestad, Anne Merete Aaland; Lien, Egil; Espevik, Terje; Anthonsen, Marit Walbye. (2006) Double-stranded RNA induces association of TLR3 with c-Src tyrosine kinase on endosomes to initiate antiviral signaling. Toll2006 - Recent Advances in Pattern Recognition
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Contribution to radio or TV
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Conference lectureRokstad, Anne Mari Aukan; Donati, Ivan; Borgogna, Massilimo; Oberholzer, José; Strand, Berit Løkensgard; Espevik, Terje; Skjåk-Bræk, Gudmund. (2006) Cell-compatible covalent alginate beads obtained from a chemoenzymatically engineered alginate. XIV International workshop on bioencapsulation & COST 865 meeting
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LectureSandanger, Øystein; Ryan, Liv; Halaas, Øyvind; Iversen, Ann-Charlotte; Bohnhorst, Janne Øvrebø; Espevik, Terje. (2006) Characterization of MD-2 localization and expression using a newly developed monoclonal antibody (IIC1). Keystone Symposium
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LectureEspevik, Terje. (2006) Functions of Toll-like receptor 4 involving endosomes. 4th International Conference on Innate Immunity
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LectureEspevik, Terje. (2006) Endocytosis and degradation of the LPS receptor complex - how and why?. University of Massachusetts
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Conference posterKlein, Dionne C.G.; Latz, Eicke; Stokke, Bjørn Torger; Espevik, Terje. (2006) Binding of different classes of CpG-DNA to Toll-like receptor 9 investigated with fluorescence correlation spectroscopy. 9th Carl Zeiss sponsored workshop on FCS and related methods
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Conference posterKlein, Dionne C.G.; Stokke, Bjørn Torger; Espevik, Terje. (2006) Visualization of the first step in activation of Toll-like receptors by atomic force microscopy and confocal microscopy. Norwegian Biophysics Meeting
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Conference posterKlein, Dionne C.G.; Stokke, Bjørn Torger; Espevik, Terje. (2006) Activation of Toll-like receptors studied by atomic force microscopy and confocal microscopy. Toll 2006, Recent Advances in Pattern Recognition
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Conference posterHusebye, Harald; Halaas, Øyvind; Stenmark, Harald; Tunheim, G; Sandanger, Øystein; Brech, A; Bogen, B; Latz, Eicke; Espevik, Terje. (2006) Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity. Toll2006 Meeting
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Conference posterHusebye, Harald; Halaas, Øyvind; Stenmark, Harald; Tunheim, G; Sandanger, Øystein; Brech, A; Bogen, B; Latz, Eicke; Espevik, Terje. (2006) Functions associated with intracellular traficking of Toll-like receptor 4. EMBO Conference "Interface of Cell Biology and Cellular Microbiology: Macormolecular Complexes in Microbial Pathogenesis, Membrane Trafficking and Cell Signaling"
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Conference posterHusebye, Harald; Halaas, Øyvind; Stenmark, Harald; Tunheim, G; Sandanger, Øystein; Brech, A; Bogen, B; Latz, Eicke; Espevik, Terje. (2006) Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity. Norsk Biokjemisk Selskap Trøndelag
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Conference lecture
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Conference lectureEspevik, Terje. (2006) Immunostimulating alginates: Highlights from our research and some future perspectives. NTNU Seminar i anledning professor G. Skjåk-Bræks 60 yr anniversary
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Conference lectureEspevik, Terje. (2006) Intracellular trafficking and signalling of Toll-like receptors. EMBO Conference, Macro Molecular Complexes in Microbial Pathogenesis Membrane Trafficking and Cell Singalling.
2005
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Conference posterJohnsen, Ingvild Bjellmo; Ringdal, Monika; Tryggestad, Anne Merete Aaland; Nguyen, Thank Thuy Thi; Lien, Egil; Espevik, Terje; Anthonsen, Marit Walbye. (2005) Double-stranded RNA induces association of TLR3 with c-Src tyrosine kinase on endosomes to initate antiviral signaling. 2nd ESF Functional Genomics Conference
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Conference lecture
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Conference lectureEspevik, Terje. (2005) Hvordan oppdager det medfødte immunsystemet mikroorganismer. Institutt for bioteknologi på Gløshaugen, seminar
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Conference lectureEspevik, Terje. (2005) How can we use systems biology to study host defence mechanisms of innate immunity. NTNU møte
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Conference lectureEspevik, Terje. (2005) Medfødt immunitet studert ved hjelp av optiske avbildingsteknikker. Lokal FUGE komitè
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Conference lectureEspevik, Terje. (2005) Endocytosis and degradation of the LPS receptor complex, how and why?. EU-prosjektmøte i AMIS
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Conference lecture
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Conference posterPukstad, Brita; Ryan, Liv; Jones, S; Thomas, DW; Harding, KG; Espevik, Terje. (2005) An investigation of toll-like receptor interaction with bacteria in the pathogenesis of chronic leg ulcers. Vintermøte i Tromsø
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Conference lectureEspevik, Terje. (2005) Functions of Toll-like receptors in the immune system. The Norwegian Biochemical Society 41st Contact Meeting
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Conference posterJohnsen, Ingvild Bjellmo; Ringdal, Monika; Tryggestad, Anne Merete; Lien, Egil; Espevik, Terje; Anthonsen, Marit Walbye. (2005) Double-stranded RNA induces association of TLR3 with c-Src tyrosine kinase on endosomes to initate antiviral signaling. The Norwegian Biochemical Society 41st Contact Meeting
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Conference posterBohnhorst, Janne Øvrebø; Fløttum, Marianne; Rasmussen, T; Børset, Magne; Sundan, Anders; Espevik, Terje; Moen, Siv H. (2005) A possible role of toll-like receptors in multiple myeloma. The Norwegian Biochemical Society 41st Contact Meeting
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Conference posterNguyen, Thank Thuy Thi; Johnsen, Ingvild Bjellmo; Hagen, Lars; Torseth, Kathrin; Espevik, Terje; Slupphaug, Geir; Anthonsen, Marit Walbye. (2005) Identification of novel proteins associated with a pathogen patten recognition receptor mediating antiviral immune responses. The Norwegian Biochemical Society 41st Contact Meeting
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Conference posterRokstad, Anne Mari Aukan; Strand, Berit Løkensgard; Rian, Kristin; Steinkjer, Bjørg; Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund; Espevik, Terje. (2005) Making alginate bioreactors for treatment of brain tumours: strategies for optimalisation of the system. The Norwegian Biochemical Society 41st Contact Meeting
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Conference posterEspevik, Terje; Husebye, Harald; Bohnhorst, Janne Øvrebø; al., diverse et. (2005) Functions of Toll-like receptors in the immune system. The Norwegian Biochemical Society 41st Contact Meeting
2004
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Conference lectureHalaas, Øyvind; Husebye, Harald; Stenmark, Harald; Latz, E; Espevik, Terje. (2004) Molecular mechanisms for endocytosis of the LPS receptor complex. 12th International Congress of Immunology
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Conference lecturePukstad, Brita; Ryan, Liv; Espevik, Terje. (2004) An investigation of toll-like receptor interaction with bacteria in the pathogenesis of chronic leg ulcers. WUWHS (World Union Wound Healing Society)
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Conference posterDahle, Maria K; Øverland, Gunhild; Myhre, Anders; Stuestøl, Jon Fredrik; Espevik, Terje; Hartung, T; Aasen, A. O.. (2004) TOLL-LIKE RECEPTOR REGULATION AND SIGNALLING IN KUPFFER CELLS. Surgical Infection Society, 23rd Annual Meeting in San-Antonio
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Conference posterJohnsen, Ingvild Bjellmo; Ringdal, Monika; Tryggestad, Anne Merete Aaland; Espevik, Terje; Anthonsen, Marit Walbye. (2004) Double-stranded RNA induces TLR3-mediated c-Src-dependent Akt activation in human monocyte-derived dendritic cells. Toll 2004
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Conference lectureJohnsen, Ingvild Bjellmo; Espevik, Terje; Anthonsen, Marit Walbye. (2004) Konfokalmikroskopi - Antiviral immunrespons. Interessegruppe for konfokalmikroskopi
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Conference lectureNilsen, Nadra; Espevik, Terje. (2004) Molecular associations of lipopeptides with CD14 and TLR2. Toll 2004
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Conference lectureEspevik, Terje. (2004) Trafficking of Toll-like receptors. 6th World Congress on Trauma, Shock, Inflammation and Sepsis - Patho
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Conference lectureJohnsen, Ingvild Bjellmo; Lien, Egil; Espevik, Terje; Anthonsen, Marit Walbye. (2004) Double-stranded RNA is internalized through clathrin-mediated endocytosis and trafficks to tubular lysosomes. Toll 2004
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Conference lectureBohnhorst, Janne Øvrebø; Fløttum, M; Rasmussen, T; Børset, Magne; Sundan, Anders; Espevik, Terje. (2004) Abnormal expression of toll-like receptors in multiple myeloma. Toll Meeting 2004
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Conference lectureEspevik, Terje. (2004) Toll-like receptors in inflammatory responses, signalling mechanisms, oncology - cardiology - neurology - osteoporosis - diabetes. Rikshospitalet
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Conference lectureHusebye, Harald; Halaas, Øyvind; Espevik, Terje. (2004) Molecular mechanisms for endocytosis of the LPS receptor complex. Toll 2004
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Conference lectureNilsen, Nadra; Nonstad, U; Knetter, Cathrine; Sundan, Anders; Espevik, Terje; Lien, Egil. (2004) Lipopolysaccharide- and dsRNA-Induced Upregulation of Mouse Tollike Receptor 2 is Myeloid Differentiation Factor 88-Independent. Toll 2004
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Conference lectureJohnsen, Ingvild Bjellmo; Ringstad, M; Tryggestad, A; Espevik, Terje; Anthonsen, Marit Walbye. (2004) Double-stranded RNA induces TLR-3-mediated c-Src-dependent Akt activation in human monocyte-derived dindritic cells. Toll 2004
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Conference lectureRyan, Liv; Vik, R; Moen, S; Steinkjer, B; Iversen, Ann-Charlotte; Sundan, Anders; Espevik, Terje. (2004) Generation and characterization of new monoclonal antibodies against human MD-2. Toll 2004
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Conference lectureBohnhorst, Janne Øvrebø; Fløttum, M; Rasmussen, T; Børset, Magne; Sundan, Anders; Espevik, Terje. (2004) Abnormal expression of toll-like receptors in multiple myeloma. 12th International Congress of Immunology
2003
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Conference posterManoukian, M; Triantafilou, M; Triantafilou, K; Mackie, A; Nilsen, Nadra; Espevik, Terje; Wiesmüller, K.H.; Ulmer, A. J.; Heine, H. (2003) Molecular mechanisms of lipopeptide interaction with CD14 and TLR2. 34th Annual Meeting of the German Society of Immunology
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LectureEspevik, Terje. (2003) Toll lignende reseptor 4: kroppens sensor for endotoksin. Biokjemisk interessegruppe ved Rikshospitalet
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Lecture
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Conference lectureStrand, Berit Løkensgard; Mørch, Yrr Asbjørg; Espevik, Terje; Skjåk-Bræk, Gudmund. (2003) Improvement of alginate microcapsules using Ba2+ - and Sr2+ -ions and biopolymer engineering. 6th International Congress of the Cell Transplant Society
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Conference posterStrand, Berit Løkensgard; Mørch, Yrr Asbjørg; Espevik, Terje; Skjåk-Bræk, Gudmund. (2003) Improvement of alginate microcapsules using Ba2+- and Sr2+-ions and biopolymer engineering. 6th International Congress of the Cell Transplant Society
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Conference lectureEspevik, Terje. (2003) Polymer og kompositter - myke materialer - anvendelser innen medisinsk teknologi. Seminar på Jægtvolden
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Conference lectureEspevik, Terje. (2003) Applications of fluorescent Toll gene constructs�. Host Pathogen Interactions
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Conference lectureEspevik, Terje. (2003) Cell Distributions and Functions of Toll-like Receptor 4 Studied by Fluorescent Gene Constructs. Karolinska Institutet, Nobel Symposium no 124, Septicemia and Shock: Pathogenesis and Novel Therapeutic Strategies
2002
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LectureEspevik, Terje. (2002) Trafficing and signalling of lipopolysaccharide studied by fluorescent gene constructs. [Mangler data]
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Lecture
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Conference lectureEspevik, Terje. (2002) HOSPATH: Towards control of septic shock induced by gram-positive bacteria: host pathogen interactions. The Euro Conference on Sepsis and Inflammation
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Conference lectureEspevik, Terje. (2002) TLR/CD14-fluorescent protein constructs to study interactions between the receptors using dynamic confocal microscopy. HOSPATH Mid Term Evaluation of EU Project.
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Conference lecture
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Conference lectureEspevik, Terje. (2002) Toll-lignende reseptor 4 - kroppens sensor for endotoxin. Norsk Biokjemisk Selskaps julemøte.
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Conference lectureEspevik, Terje. (2002) Monocytes stimulated with Group B streptococci or IFNs release soluble TRAIL. HOSPATH Mid Term Evaluation of Project
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Conference lecture
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Conference posterNilsen, Nadra; Nonstad, Unni; Sundan, Anders; Espevik, Terje; Lien, Egil. (2002) Function and expression of mouse Toll-like receptor 2, a receptor for bacterial, fungal and viral components. The 7th Biennial Conference of the International Endotoxin Society.
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Conference posterMoen, Siv H; Flo, Trude Helen; Ryan, Liv; Espevik, Terje; Sundan, Anders. (2002) Generation and functional characterization of human toll-like (TLR) 6. 38.Biokjemiske kontaktmøte Functional genomics-the mosaics of life
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Conference posterLatz, Eicke; Visintin, A; Lien, Egil; Fitzgerald, KA; Golenbock, Douglas T.; Espevik, Terje. (2002) The LPS receptor studied by fluorescent constructs. The 7th Biennial Conference of the International Endotoxin Society
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Conference posterAdib-Conquy, M; Moine, P; Asehnoune, K; Espevik, Terje; Miyake, K; Werts, C; Cavaillon, J-M. (2002) TLR2-, TLR4- and TLR9-mediated TNF and IL-10 production are not similarly affected during systemic inflammation. The 7th Biennal Conference of the International Endotoxin Society
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Conference posterRyan, Liv; Flo, Trude Helen; Takeuchi, Osamu; Lien, Egil; Halaas, Øyvind; Akira, Shizuo; Skjåk-Bræk, Gudmund; Espevik, Terje. (2002) Involvement of TLR2 and TLR4 in activation of monocytes/macrophages by mannuronic acid polymers. The International Union of Biochemistry and Molecular Biology 7th IUBMB Conference RECEPTOR-LIGAND INTERACTIONS Molecular, Physiological and Pharmacological Aspects
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Conference posterIversen, Ann-Charlotte; Steinkjer, Bjørg; Sundan, Anders; Espevik, Terje. (2002) Selective TRAIL Expression and Utilization of Ligand Mediated Cytotoxicity in Interferon Activated Human NK Cells. The International Union of Biochemistry and Molecular Biology 7th IUBMB Conference RECEPTOR-LIGAND INTERACTIONS Molecular, Physiological and Pharmacological Aspects
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Conference posterHalaas, Øyvind; Vik, Randi; Liabakk, Nina-Beate; Sundan, Anders; Espevik, Terje. (2002) Group B streptococci and interferons induce upregulation of membrane TRAIL on monocytes and cell death-dependent release of soluble TRAIL. 38.Biokjemiske kontaktmøte Functional genomics-the mosaics of life
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Conference posterNonstad, Unni; Espevik, Terje; Lien, Egil. (2002) Expression and regulation of mouse Toll-like receptor 2. 38.Biokjemiske kontaktmøte Functional genomics-the mosaics of life
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Conference posterEspevik, Terje; Latz, Eicke; Lien, Egil; Monks, B. G.; Golenbock, Douglas T.. (2002) Cell distributions and functions of TLRs as studied by fluorescent constructs. The 7th Biennal Conference of the International Endotoxin Society
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Conference posterRyan, Liv; Flo, Trude Helen; Takeuchi, Osamu; Lien, Egil; Halaas, Øyvind; Akira, Shizuo; Skjåk-Bræk, Gudmund; Espevik, Terje. (2002) Involvement of TLR2 and TLR4 in activation of monocytes/macrophages by mannuronic acid polymers. 38.Biokjemiske kontaktmøte Functional genomics-the mosaics of life
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Conference lectureEspevik, Terje. (2002) Involvement of Toll-like receptor (TLR) 2 and TLR4 in cell activation by mannuronic acid polymers. International Union of Biochemistry and Molecular Biology
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Conference lectureEspevik, Terje. (2002) Immune stimulating effects of alginates - relation to Toll-like receptor signalling. Forskningsparken
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Feature article
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Conference lecture
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Conference lecture
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Conference lectureEspevik, Terje. (2002) Cell distributions and functions of Toll-like receptors studied by fluorescent gene constructs. University of Massachusetts
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Conference lectureEspevik, Terje. (2002) Toll-like receptors: sensors for pathogens in the innate immune system. EU-network Conference on Antigen Presentation.
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Conference lectureRokstad, Anne Mari Aukan; Strand, Berit Løkensgard; Rian, Kristin; Steinkjer, Bjørg; Ryan, Liv; Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund; Espevik, Terje. (2002) Evaluation of different alginate microcapsules as bioreactors for 293-EBNA cells delivering the anti-angiogenic factor endostatin. 38.Biokjemiske kontaktmøte Functional genomics-the mosaics of life
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Conference lectureEspevik, Terje. (2002) Involvement of Toll-like receptor (TLR)2 and TLR4 in cell activation by mannuronic acid polymers. The 7th IUBMB Conference RECEPTOR-LIGAND INTERACTIONS
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Conference lectureFalch, Berit H.; Espevik, Terje; Stokke, Bjørn Torger. (2002) (1->3)-beta-D-Glucan structures and immunostimulation in vitro. XXIst Internactional Carbohydrate Symposium, Cairns, Australia, July 7 - 12, 2002.
2001
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Conference lectureEspevik, Terje. (2001) Functions and trafficking of Toll-like receptors as studied by fluorescent gene constructs. 2nd Congress on Gram Positive Sepsis
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Conference poster
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Conference lectureEspevik, Terje. (2001) Toll-like receptors: sensors for pathogens in the innate immune system. Rikshospitalet
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Conference lectureEspevik, Terje. (2001) Involvement of TLR-2 and TLR-4 in activation of monocytes/macrophages by mannuronic acid polymers. Boston University Medical Center
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Conference posterIversen, Ann-Charlotte; Sundan, Anders; Espevik, Terje. (2001) IFN-alpha and IFN-beta induce TRAIL-mediated NK cell cytotoxicity. Keystone Symposia Molecular Aspects of Viral Immunity
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Conference lectureEspevik, Terje. (2001) Properties of fluorescent TLR constructs. Department of Infectious Diseases University of Boston
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Conference posterWestern, K. H.; Thompson, Keith; Aarvak, Tanja; Flo, T. H.; Espevik, T; Bogen, Bjarne. (2001) Toll-like receptors are involved in antigen capture and presentation on MHC class II molecules to CD4+ T cells and serve as a link between innate and adaptive immunity. Meeting: Interfaces between innate and adaptive immunity (J3).
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Conference lectureWang, Jacob Edward; Warris, A.; Ellingsen, Espen Alme; Jørgensen, Pål Foyn; Flo, T. H.; Espevik, T; Solberg, Rigmor; Verweij, P. E.; Aasen, Ansgar Oddne. (2001) Involvement of CD 14 and toll-like receptors in signaling by Aspergillus hypae. Surigal Infection Society-Europe
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Conference lectureStrand, Berit Løkensgard; Mørch, Yrr Asbjørg; Rokstad, Anne Mari Aukan; Kulseng, Bård Eirik; Espevik, Terje; Skjåk-Bræk, Gudmund. (2001) Improved capsule properties by the use of epimerised alginate. The Ninth International Workshop in Bioencapsulation
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Conference posterLatz, Eicke; Lien, Egil; Monks, B. G.; Golenbock, D; Espevik, Terje. (2001) Cell distribution and functions of TLRs as studied by fluoroscent TLR constructs. 2nd Meeting on Septic Shock caused by Gram-positive bacteria.
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Conference posterWestern, Karoline H; Aarvik, Tanja; Thompson, Ketih; Flo, Trude Helen; Espevik, Terje. (2001) Toll-like receptors are involved in antigen capture and presentation on MHC class II molecules to CD4+ T cells and serve as a link between innate and adaptive immunity. Keystone Symposia
2000
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LectureFlo, Trude Helen; Ryan, Liv; Halaas, Øyvind; Dybdal, Brit; Lien, Egil; Sundan, Anders; Espevik, Terje. (2000) Detection of soluble TLR2 in human serum samples by ELISA. The 6th Conference of The International Endotoxin Society
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LectureHalaas, Øyvind; Flo, Trude Helen; Dybdal, Brit; Torp, Sverre Helge; Lien, Egil; Sundan, Anders; Espevik, Terje. (2000) Expression pattern of toll-like receptor 2. 6th Conference of the International Endotoxin Society
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LectureFlo, Trude Helen; Halaas, Øyvind; Lien, Egil; Ryan, Liv; Teti, Guiseppe; Golenbock, Douglas T.; Sundan, Anders; Espevik, Terje. (2000) Human toll-like receptor 2 mediates monocyte activation by listeria monocytogenes, but not by group B streptococci or lipopolysaccharide. The 36th Norwegian Biochemical Society Meeting
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LectureHalaas, Øyvind; Vik, Randi; Ashkenazi, Avi; Espevik, Terje. (2000) LPS indueces expression of APO2 ligand/TRAIL in human monocytes and macrophages. 8th International TNF Congress CONFERENCE ON TUMOR NECROSIS FACTOR AND RELATED MOLECULES SCIENTIFIC ADVANCES AND MEDICAL APPLICATIONS
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LectureFlo, Trude Helen; Halaas, Øyvind; Dybdal, Brit; Torp, Sverre Helge; Lien, Egil; Miyake, Kensuke; Golenbock, Douglas T.; Sundan, Anders; Espevik, Terje. (2000) Expression and functions of toll-like receptor 2. The 8th International TNF Congress
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LectureStrand, Berit; Holtan, Synnøve; Espevik, Terje; Skjåk-Bræk, Gudmund. (2000) Alginate AS Immibilsation materials for cells. Bioartificial Organs III
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Conference posterLiabakk, Nina-Beate; Torp, Sverre Helge; Sundan, Anders; Espevik, Terje. (2000) Detection of trail in human serum and in tissues. 8th International TNF Congress on Tumor Necrosis Factor and Related Cytokines
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Conference posterIversen, Ann-Charlotte; Steinkjer, Bjørg; Liabakk, Nina-Beate; Sundan, Anders; Espevik, Terje. (2000) Interferon-beta is a potent inducer of TRAIL expression in human NK cells. 8th International TNF Congress on Tumor Necrosis Factor and Related Cytokines
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Conference posterRokstad, Anne Mari Aukan; Kulseng, Bård Eirik; Strand, B.; Skjåk-Bræk, Gudmund; Espevik, Terje. (2000) Transplantation of Alginate Microcapsules with proliferating cells in mice: Capsular overgrowth and survival of encapsulated cells in allo-and xeno graft modells. Bioartificial organs III. Tissue Sourcing, Immunosolation and Clinical Trials.
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Conference posterStrand, Berit Løkensgard; Kulseng, Bård Eirik; Rokstad, Anne Mari Aukan; Skjåk-Bræk, Gudmund; Espevik, Terje. (2000) Identification of cells in the fibrotic reaction against transplanted encapsulated cells. Islets in Eilat: A combined islet basic science and transplantation meeting
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Conference posterHalaas, Øyvind; Vik, Randi; Ashkenazi, Avi; Espevik, Terje. (2000) LPS induces expression of APO2 ligand/TRAIL in human monocytes and macrophages. 8th International Congress on Tumor Necrosis Factor and Related Cytokines.
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Conference posterFlo, T.H.; Halaas, Ø.; Dybdahl, B.; Torp, S.H.; Lien, E.; Mikyake, K.; Golenbock, D.; Sundan, A.; Espevik, Terje. (2000) Expression and functions of Toll like receptor 2. 8th International TNF Congress
1999
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Conference lectureStrand, Berit Løkensgard; Kulseng, Bård Eirik; Espevik, Terje; Skjåk-Bræk, Gudmund. (1999) Innkapsling av insulinproduserende celler til transplantasjon av diabetespasienter. Bioingeniørdagen
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LectureEspevik, Terje. (1999) Immune responses against alginate microcapsules. The Eight International Workshop on Bioencapsulation. Recent Progress in Research and Technology
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Lecture
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LectureEspevik, Terje. (1999) Alginatkapsler - fra champagne produksjon til behandling av sykdommer. [Mangler data]
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LectureRyan, Liv; Strand, Berit; Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund; Espevik, Terje. (1999) Characterisation of the toxic and cytokine inducing properties of poly-L-lysine used in alginate microcapsules. 35. Biokjemiske Kontaktmøte NBS
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LectureStrand, Berit Løkensgard; Ryan, Liv; IntVeld, Peter; Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund; Espevik, Terje. (1999) Characterisation of the toxic and cytokine inducing properties of poly-L-lysine used in alginate microcapsules. The Eight International Workshop in Bioencapsulation. Recent Progress in Research and Technology
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LectureStrand, Berit Løkensgard; Ryan, Liv; IntVeld, Peter; Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund; Espevik, Terje. (1999) Characterisation of the toxic and cytokine inducing properties of poly-L-lysine used in alginate microcapsules. 7th World Congress of the International Pancreas & Islet Transplant Association
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LectureRokstad, Anne Mari Aukan; Espevik, Terje; Skjåk-Bræk, Gudmund; Vadstein, Olav; Skjermo, Jorun. (1999) Alginates as adjuvant in fish vaccine against Aeromonas salmonicida. 35. Biokjemiske Kontaktmøte, NBS
1998
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Lecture
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Conference posterIversen, Ann-Charlotte; Steinkjer, Bjørg; Nonstad, Unni; Egeberg, Kjartan Wøllo; Sundan, Anders; Espevik, Terje. (1998) Natural Killer cell mediated cytotoxicity involves Apo-2 Ligand/Trail. Kontaktmøte nr. 34
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Conference posterIversen, Ann-Charlotte; Haux, Johan; Steinkjer, Bjørg; Nonstad, Unni; Egeberg, Kjartan Wøllo; Ashkenazi, Avi; Sundan, Anders; Espevik, Terje. (1998) Regulation of Apo-2 Ligand/Trail expression in NK cells - Involvement in NK cell mediated cytotoxicity. 7th International Tumor Necrosis Factor Congress
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Conference posterHalaas, Øyvind; Vik, Randi; Ashkenazi, Ari; Espevik, Terje. (1998) LPS Induces Expression of Apo2ligand/TRAIL in human monocytes. The fifth conferanse of tje international endotoxin society
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LectureEspevik, Terje. (1998) Mekanismer for aktivering av celler i det medfødte immunsystemet. Årsmøte i Norsk immunologisk selskap
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LectureEspevik, Terje. (1998) Invovlement of Apo2L and FasL in NK-cell functions. Annual Meeting of the Scandinavian Society for immunology
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Lecture
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LectureEspevik, Terje. (1998) Involvement of CR3 and CR4 in the interaction of group B streptococci with cells. Norsk Biokjemisk Vintermøte
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Lecture
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LectureEspevik, Terje. (1998) Bacterial polysaccharides as cytokine inducers: the involvement of CD14 and CD18. Vibo Valentia Seminars on Shock
1997
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Conference lectureIversen, Ann-Charlotte; Medvedev, Andrei E.; Haux, Johan; Steinkjer, Bjørg; Egeberg, Kjartan Wøllo; Lynch, David H.; Sundan, Anders; Espevik, Terje. (1997) Involvement of Fas and Fas Ligand in NK/LAK mediated cytotoxicity. Kontaktmøte nr. 33
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Conference lectureEspevik, Terje; Kulseng, Bård Eirik. (1997) Transplantasjon av insulinproduserende celler i alginatkapsler. Invitert til Fredagsforelesning, RiT, direktesendt til Regionsy kehuset i Tromsø og sykehus i Midt-Norge
1996
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Conference lectureAukrust, Pål; Hestad, Kjetil; Lien, Egil; Nordøy, Ingvild; Espevik, T; Muller, Fredrik; Frøland, Stig Sophus. (1996) Downregulation of TNFa activity and increase in plasma levels of soluble Fas-antigen after intravenous immunoglobulin (IVIG) administration in vivo in HIV-infected patients are associated with increase in CD4+ lymphocyte counts. 3. International Congress on Drug Therapy in HIV Infection
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Conference lectureMuller, Fredrik; Hestad, Kjetil; Aukrust, Pål; Lien, Egil; Espevik, T; Frøland, Stig Sophus. (1996) Low expression of TNF-p75 receptor on mononuclear cells is associated with advanced immunodeficiency and high ¿viral load¿ in HIV infection. 3. International Congress on Drug Therapy in HIV Infection
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Conference lectureAukrust, Pål; Hestad, Kjetil; Lien, Egil; Nordøy, Ingvild; Espevik, T; Muller, Fredrik; Frøland, Stig Sophus. (1996) Intravenous immunoglobulin (IVIG) administration in vivo downregulate abnormally increased activity in the tumor necrosis factor (TNF) system and increase CD4+ lymphocyte counts in HIV-infected patients. First European Conference on Experimental AIDS Research
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Conference lectureLægreid, Astrid; Nonstad, Unni; Sundan, Anders; Espevik, Terje. (1996) Lipopolysaccharide signalling mechanism in human adenocarcinoma SW480 cells. 32. Biokjemiske kontaktmøte
1995
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LectureEspevik, Terje; Kulseng, Bård Eirik; Anderson, A.; Skjåk-Bræk, Gudmund. (1995) Antibody responses to alginates in different species. Lecture at B-cell, Islets and Pancreas Transplants
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LectureThu, Beate; Espevik, Terje; Smidsrød, Olav; Skjåk-Bræk, Gudmund. (1995) Alginate polycation microcapsules : improved functional properties by controlling the interaction between polycations and alginates. Symposium on Advances in Polysaccharides : Characteristics and Applications
1994
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Conference posterSamuelsen, Anne Berit; Paulsen, Berit Smestad; Wold, Jens Krisitian; Espevik, T; Otsuka, Hanako; Yamada, Haruki. (1994) Biologically active polysaccharides from Plantago major L. Norsk biokjemisk selskaps kontaktmøte
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Conference posterSamuelsen, Anne Berit; Djahromi, Jalil M.; Paulsen, Berit Smestad; Wold, Jens Krisitian; Espevik, T; Otsuka, Hanako; Yamada, Haruki. (1994) Polysaccharides from large plantain (Plantago major L.). XVIIth International Carbohydrate Symposium
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LectureSmidsrød, Olav; Skjåk-Bræk, Gudmund; Espevik, Terje. (1994) Kan alginatkuler revolusjonere diabetesbehandlingen?. Forskningskampanje - diabetesforskning
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LectureEspevik, Terje; Skjåk-Bræk, Gudmund. (1994) Immunological aspects of alginates for microencapsulation. German Diabetes Society. 29th Annual Meeting
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Conference posterIversen, Ann-Charlotte; Espevik, Terje; Sundan, Anders. (1994) Effect of lipopolysaccharide and poly mannuronic acid on NF-kappa B and cytokine induction in human monocytes and granulocytes. Kontaktmøte nr. 30
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Conference posterLien, E; Liabakk, N-B; Austgulen, Rigmor; Sunde, A; Sundan, A; Espevik, Terje. (1994) Characterization of receptors for tumor necrosis factor on sperm cells and in seminal plasma. Norsk biokjemisk vintermøte
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Conference posterArntzen, KJ; Liabakk, N-B; Jacobsen, G; Espevik, Terje; Austgulen, Rigmor. (1994) Serum levels of soluble cytokine receptors and receptor inhibitors are influenced by gestational age and delivery. Norsk biokjemisk vintermøte
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Conference posterLien, E; Liabakk, N-B; Espevik, Terje; Austgulen, Rigmor. (1994) Raised levels of tumor necrosis factor receptors in human retroplacental serum. Norsk biokjemisk vintermøte
1993
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Conference posterSamuelsen, Anne Berit; Paulsen, Berit Smestad; Wold, Jens Krisitian; Espevik, T; Otsuka, Hanako; Yamada, Haruki. (1993) Polysaccharides from Plantago major - isolation, charracterization and testing of biological activity. Phytochemistry of plants used in traditional medicine
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Conference posterIversen, Ann-Charlotte; Naume, Bjørn; Espevik, Terje; Sundan, Anders. (1993) Analysis of IL-2, IL-7- and IL-12-induced cytokine gene expression by RT-PCR in purified NK cells. Kontaktmøte nr. 29
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Conference posterAustgulen, Rigmor; Liabakk, N-B; Richardsen, W; Rahimipoor, S; Vatn, I; Espevik, Terje. (1993) Serum levels of soluble TNF receptors are influenced by gestational age and delivery in normal human pregnancy. 5th Meeting of the European Placenta Group
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Conference posterAustgulen, Rigmor; Liabakk, N-B; Lien, E; Vince, G; Espevik, Terje. (1993) Occurence of soluble TNF receptors in association with normal delivery at term. Norsk biokjemisk selskaps vintermøte
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Conference posterLiabakk, N-B; Sunde, A; Austgulen, Rigmor; Espevik, Terje. (1993) High concentrations of soluble TNF receptor p55 in seminal plasma. Norsk biokjemisk selskaps vintermøte
1992
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Conference posterLiabakk, N-B; Austgulen, Rigmor; Espevik, Terje. (1992) Soluble TNF receptors in urine and in amniotic fluid from pregnant women. Norsk biokjemisk selskaps vintermøte
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Conference posterLiabakk, N-B; Austgulen, Rigmor; Lien, E; Espevik, Terje. (1992) Raised levels of the 55kD TNF receptor in pregnant women and in newborns. The 4th International TNF Congress
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Conference posterAustgulen, Rigmor; Liabakk, N-B; Lien, E; Espevik, Terje. (1992) Raised levels of the 55kD TNF receptor in serum and in urine samples from newborns and from pregnant women. The 5th International Congress of Reproductive Immunology
1991
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Conference posterAustgulen, Rigmor; Liabakk, N-B; Scott, H; Brockhaus, M; Espevik, Terje. (1991) Soluble TNF receptors in urine and in amniotic fluid from pregnant women. IV Meeting of the European Placenta Group
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Conference posterLiabakk, N-B; Austgulen, Rigmor; Espevik, Terje. (1991) Detection of soluble TNF receptors in urine and amniotic fluid from pregnant women. Keystone symposium on Molecular and Cellular Biology
1986
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Conference posterAustgulen, Rigmor; Espevik, Terje; Nissen-Meyer, J. (1986) Human monocyte stimulation of fibroblast growth by soluble mediator(s). Scandinavian Society of Immunology
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Conference posterEspevik, Terje; Austgulen, Rigmor; Nissen-Meyer, J. (1986) Mechanism of monocyte-mediated killing of tumor cells: the monocyte cytotoxic factor (CF) identified as tumor necrosis factor (TNF). Scandinavian Society of Immunology