2024

• Olsen, Maria Belland; Kong, Xiang Yi; Louwe, Maria; Lauritzen, Knut Husø; Schanke, Ylva; Kaasbøll, Ole Jørgen. (2024) SLAMF1-derived peptide exhibits cardio protection after permanent left anterior descending artery ligation in mice. Frontiers in Immunology
  Academic article
• Fageräng, Beatrice Linnea Christina; Cyranka, Leon; Schjalm, Camilla; Ekholt, Karin; Larsen, Carina Sandem; Heinzelbecker, Julia. (2024) The function of the complement system remains fully intact throughout the course of allogeneic stem cell transplantation. Frontiers in Immunology
  Academic article

2023

• Bjerkhaug, Aline; Granslo, Hildegunn Norbakken; Cavanagh, Jorunn Pauline; Høiland, Ina Isabella; Ludviksen, Judith K; Lau, Corinna. (2023) Dual inhibition of complement C5 and CD14 attenuates inflammation in a cord blood model. Pediatric Research
  Academic article
• Lentini, Germana; Famà, Agata; De Gaetano, Giuseppe Valerio; Coppolino, Francesco; Mahjoub, Ahlem Khachroub; Ryan, Liv. (2023) Caspase-8 inhibition improves the outcome of bacterial infections in mice by promoting neutrophil activation. Cell Reports Medicine
  Academic article
• Nilsen, Kaja Elisabeth; Zhang, Boyao; Skjesol, Astrid; Ryan, Liv; Vagle, Hilde; Bøe, Maren Helene. (2023) Peptide derived from SLAMF1 prevents TLR4-mediated inflammation in vitro and in vivo. Life Science Alliance (LSA)
  Academic article

2022

• Pinto, Sneha M.; Subbannayya, Yashwanth; Kim, Hera; Hagen, Lars; Górna, Maria W; Nieminen, Anni I.. (2022) Multi-OMICs landscape of SARS-CoV-2-induced host responses in human lung epithelial cells. iScience
  Academic article
• Johnson, Christina; Quach, Huy Quang; Lau, Corinna; Ekholt, Karin; Espevik, Terje; Woodruff, Trent M.. (2022) Thrombin Differentially Modulates the Acute Inflammatory Response to Escherichia coli and Staphylococcus aureus in Human Whole Blood. Journal of Immunology
  Academic article
• Nilsen, Kaja Elisabeth; Skjesol, Astrid; Kojen, June Frengen; Espevik, Terje; Stenvik, Jørgen; Yurchenko, Mariya. (2022) TIRAP/Mal Positively Regulates TLR8‐Mediated Signaling via IRF5 in Human Cells. Biomedicines
  Academic article

2021

• Islam, Rakibul; Islam, Mohammad Mirazul; Nilsson, Per H.; Mohlin, Camilla; Hagen, Kjersti Thorvaldsen; Paschalis, Eleftherios I.. (2021) Combined blockade of complement C5 and TLR co-receptor CD14 synergistically inhibits pig-to-human corneal xenograft induced innate inflammatory responses. Acta Biomaterialia
  Academic article
• Niyonzima, Nathalie; Rahman, Jubayer; Kunz, Natalie; West, Erin; Freiwald, Tilo; Desai, Jigar V.. (2021) Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation . Science immunology
  Academic article
• Trifonov, Lena; Yurchenko, Mariya; Skjesol, Astrid; Cohen, Guy; Espevik, Terje; Korshin, Edward E.. (2021) Benzyl-para-di-[5-methyl-4-(n-octylamino) pyrimidin-2(1H)one] as an interferon beta (IFN-β) modulator. Molecular diversity
  Academic article
• Kim, Hera; Subbannayya, Yashwanth; Humphries, Fiachra; Skjesol, Astrid; Pinto, Sneha M.; Giambelluca, Miriam. (2021) UMP-CMP kinase 2 gene expression in macrophages is dependent on the IRF3-IFNAR signaling axis. PLOS ONE
  Academic article

2020

• Ehrnstrøm, Birgitta; Kojen, June Frengen; Giambelluca, Miriam; Ryan, Liv; Moen, Siv Helen; Hu, Zhenyi. (2020) TLR8 and complement C5 induce cytokine release and thrombin activation in human whole blood challenged with Gram-positive bacteria. Journal of Leukocyte Biology
  Academic article
• Niyonzima, Nathalie; Bakke, Siril Skaret; Gregersen, Ida; Holm, Sverre; Sandanger, Øystein; Orrem, Hilde Lang. (2020) Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis. EBioMedicine
  Academic article

2019

• Skjesol, Astrid; Yurchenko, Mariya; Bösl, Korbinian; Gravastrand, Caroline S.; Nilsen, Kaja Elisabeth; Grøvdal, Lene Melsæther. (2019) The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2. PLoS Pathogens
  Academic article
• Pilely, Katrine; Bakke, Siril Skaret; Palarasah, Yaseelan; Skjoedt, Mikkel-Ole; Bartels, Emil D.; Espevik, Terje. (2019) Alpha-cyclodextrin inhibits cholesterol crystal-induced complement-mediated inflammation: A potential new compound for treatment of atherosclerosis. Atherosclerosis
  Academic article
• Lau, Corinna; McAdam, Martin Berner; Bergseth, Grete; Grevys, Algirdas; Bruun, Jack-Ansgar; Ludviksen, Judith K. (2019) NHDL, a recombinant VL/VH hybrid antibody control for IgG2/4 antibodies. mAbs
  Academic article
• Thomas, Anub Mathew; Gerogianni, Alexandra; McAdam, Martin Berner; Fløisand, Yngvar; Lau, Corinna; Espevik, Terje. (2019) Complement component C5 and TLR molecule CD14 mediate heme-induced thromboinflammation in human blood. Journal of Immunology
  Academic article
• Moen, Siv Helen; Ehrnstrøm, Birgitta; Kojen, June Frengen; Yurchenko, Mariya; Beckwith, Kai Sandvold; Afset, Jan Egil. (2019) Human Toll-like receptor 8 (TLR8) is an important sensor of pyogenic bacteria, and is attenuated by cell surface TLR signaling. Frontiers in Immunology
  Academic article
• Christensen, Jacob J.; Bakke, Siril Skaret; Ulven, Stine Marie; Retterstøl, Kjetil; Henriksen, Tore; Bollerslev, Jens. (2019) Serum Omega-6 Fatty Acids and Immunology-Related Gene Expression in Peripheral Blood Mononuclear Cells: A Cross-Sectional Analysis in Healthy Children. Molecular Nutrition & Food Research
  Academic article
• Gravastrand, Caroline S.; Steinkjer, Bjørg; Halvorsen, Bente; Landsem, Anne; Skjelland, Mona; Jacobsen, Eva Astrid. (2019) Cholesterol Crystals Induce coagulation Activation through Complement-Dependent Expression of Monocytic Tissue Factor. Journal of Immunology
  Academic article
• Narverud, Ingunn; Christensen, Jacob J.; Bakke, Siril Skaret; Ulven, Stine Marie; Rundblad, Amanda; Aukrust, Pål. (2019) Profiling of immune-related gene expression in children with familial hypercholesterolaemia. Journal of Internal Medicine
  Academic article
• Bösl, Korbinian; Kandasamy, Richard Kumaran; Espevik, Terje. (2019) Novel insights on human–virus interactions through genome–wide approaches. Norwegian University of Science and Technology
  Doctoral dissertation
• Skjeflo, Espen Waage; Christiansen, Dorte; Landsem, Anne; Stenvik, Jørgen; Woodruff, T. M.; Espevik, Terje. (2019) Phagocytosis of live and dead Escherichia coli and Staphylococcus aureus in human whole blood is markedly reduced by combined inhibition of C5aR1 and CD14. Molecular Immunology
  Academic article
• Lunde, Ngoc Dieu Nguyen; Gregersen, Ida; Ueland, Thor; Shetelig, Christian; Holm, Sverre; Kong, Xiang Yi. (2019) Legumain is upregulated in acute cardiovascular events and associated with improved outcome – potentially related to anti-inflammatory effects on macrophages. Atherosclerosis
  Academic article

2018

• Kleveland, Ola; Ueland, Thor; Kunszt, Gabor; Bratlie, Marte; Yndestad, Arne; Broch, Kaspar. (2018) Interleukin-6 receptor inhibition with tocilizumab induces a selective and substantial increase in plasma IP-10 and MIP-1β in non-ST-elevation myocardial infarction. International Journal of Cardiology
  Academic article
• Thomas, Anub Mathew; Schjalm, Camilla; Nilsson, Per; Lindenskov, Paal Helge H.; Rørtveit, Runa; Solberg, Rønnaug. (2018) Combined Inhibition of C5 and CD14 Attenuates Systemic Inflammation in a Piglet Model of Meconium Aspiration Syndrome. Neonatology
  Academic article
• Skjeflo, Espen Waage; Christiansen, Dorte; Fure, Hilde; Ludviksen, Judith K; Woodruff, Trent M.; Espevik, Terje. (2018) Staphylococcus aureus-induced complement activation promotes tissue factor-mediated coagulation. Journal of Thrombosis and Haemostasis
  Academic article
• Yurchenko, Mariya; Skjesol, Astrid; Ryan, Liv; Richard, Gabriel Mary; Kandasamy, Richard Kumaran; Wang, Ninghai. (2018) SLA MF1 is required for TLR4-mediated TRAM-TRIF- dependent signaling in human macrophages. Journal of Cell Biology
  Academic article
• Nejati Moharrami, Neda; Tande, Erlend Bjørkøy; Ryan, Liv; Espevik, Terje; Boyartchuk, Victor. (2018) RORα controls inflammatory state of human macrophages. PLOS ONE
  Academic article
• Bösl, Korbinian; Giambelluca, Miriam; Haug, Markus; Bugge, Marit; Espevik, Terje; Kandasamy, Richard Kumaran. (2018) Coactivation of TLR2 and TLR8 in primary human monocytes triggers a distinct inflammatory signaling response. Frontiers in Physiology
  Academic article
• Christ, Anette; Günther, Patrick; Lauterbach, Mario A.R.; Duewell, Peter; Biswas, Debjani; Pelka, Karin. (2018) Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming. Cell
  Academic article
• Nejati Moharrami, Neda; Boyartchuk, Victor; Espevik, Terje. (2018) Role of CD5L in control of human innate immune function. Doktoravhandlinger ved NTNU (395)
  Doctoral dissertation
• Orrem, Hilde Lang; Nilsson, Per; Pischke, Søren Erik; Kleveland, Ola; Yndestad, Arne; Ekholt, Karin. (2018) IL-6 receptor inhibition by tocilizumab attenuated expression of C5a receptor 1 and 2 in non-ST-elevation myocardial infarction. Frontiers in Immunology
  Academic article
• Landsem, Anne; Fure, Hilde; Ludviksen, Judith K; Christiansen, Dorte; Lau, Corinna; Mathisen, Monica Dammen. (2018) Complement component 5 does not interfere with physiological hemostasis but is essential for Escherichia coli-induced coagulation accompanied by Toll-like receptor 4. Clinical and Experimental Immunology
  Academic article

2017

• Gregersen, Ida; Sandanger, Øystein; Askevold, Erik Tandberg; Sagen, Ellen Lund; Yang, Kuan; Holm, Sverre. (2017) Interleukin 27 is increased in carotid atherosclerosis and promotes NLRP3 inflammasome activation. PLOS ONE
  Academic article
• Ehrnstrøm, Birgitta; Beckwith, Kai Sandvold; Yurchenko, Mariya; Moen, Siv Helen; Kojen, June Frengen; Lentini, Germana. (2017) Toll-Like Receptor 8 Is a Major Sensor of Group B Streptococcus But Not Escherichia coli in Human Primary Monocytes and Macrophages. Frontiers in Immunology
  Academic article
• Gravastrand, Caroline; Hamad, Shamal; Fure, Hilde; Steinkjer, Bjørg; Ryan, Liv; Oberholzer, José. (2017) Alginate microbeads are coagulation compatible, while alginate microcapsules activate coagulation secondary to complement or directly through FXII. Acta Biomaterialia
  Academic article
• Espada Serrano, Sandra; Stavik, Benedicte; Holm, Sverre; Sagen, Ellen Lund; Bjerkeli, Vigdis; Skjelland, Mona. (2017) Tissue factor pathway inhibitor attenuates ER stress-induced inflammation in human M2-polarized macrophages. Biochemical and Biophysical Research Communications - BBRC
  Academic article
• Bakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Pilely, Katrine; Ryan, Liv; Skjelland, Mona. (2017) Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation. Journal of Immunology
  Academic article
• Stavik, Benedicte; Holm, Sverre; Espada Serrano, Sandra; Iversen, Nina; Sporsheim, Bjørnar; Bjerkeli, Vigdis. (2017) Increased expression of TFPI in human carotid stenosis. Thrombosis Research
  Academic article
• Bugge, Marit; Bergstrøm, Bjarte; Eide, Oda K.; Solli, Helene; Kjønstad, Ingrid Fadum; Stenvik, Jørgen. (2017) Surface Toll-Like Receptor 3 Expression in Metastatic Intestinal Epithelial Cells induces Selective Cytokine Production and Promotes Invasiveness. Journal of Biological Chemistry
  Academic article
• Hellerud, Bernt C; Orrem, Hilde Lang; Dybwik, Knut Gustav; Pischke, Søren Erik; Barratt-Due, Andreas; Castellheim, Albert. (2017) Combined inhibition of C5 and CD14 efficiently attenuated the inflammatory response in a porcine model of meningococcal sepsis. Journal of Intensive Care
  Academic article
• Espevik, Terje. (2017) Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation. Journal of Immunology
  Academic article
• Lunde, Ngoc Nguyen Dieu; Holm, Sverre; Dahl, Tuva Børresdatter; Inass, Elyouncha; Sporsheim, Bjørnar; Gregersen, Ida. (2017) Increased levels of legumain in plasma and plaques from patients with carotid atherosclerosis. Atherosclerosis
  Academic article
• Niyonzima, Nathalie; Halvorsen, Bente; Sporsheim, Bjørnar; Garred, Peter; Aukrust, Pål; Mollnes, Tom Eirik. (2017) Complement activation by cholesterol crystals triggers a subsequent cytokine response. Molecular Immunology
  Academic article
• Barratt-Due, Andreas; Pischke, Søren Erik; Nilsson, Per; Espevik, Terje; Mollnes, Tom Eirik. (2017) Dual inhibition of complement and Toll-like receptors as a novel approach to treat inflammatory diseases-C3 or C5 emerge together with CD14 as promising targets. Journal of Leukocyte Biology
  Academic literature review
• Stavik, Benedicte; Espada, Sandra; Holm, Sverre; Bjerkeli, Vigdis; Sandset, Per Morten; Dahl, Tuva Børresdatter. (2017) TFPI in human atherosclerotic plaques. Research and Practice in Thrombosis and Haemostasis (RPTH)
  Abstract

2016

• Varghese, Paramel G; Folkersen, Lasse; Strawbridge, Rona J.; Halvorsen, Bente; Yndestad, Arne; Ranheim, Trine. (2016) NLRP3 inflammasome expression and activation in human atherosclerosis. Journal of the American Heart Association (JAHA)
  Academic article
• Bugge, Marit; Nilsen, Nadra J.; Espevik, Terje. (2016) Toll-Like Receptor 3 Signaling in Intestinal Epithelial Cells. Norwegian University of Science and Technology
  Doctoral dissertation
• Sherstova, Tatyana; Stokke, Bjørn Torger; Anthonsen, Marit Walbye; Espevik, Terje. (2016) Quantitative atomic force microscopy and light microscopy of hydrogels and cells. Norwegian University of Science and Technology
  Doctoral dissertation
• Niyonzima, Nathalie; Freeley, Simon; Arbore, Giuseppina; Le Friec, Gaelle; Lappegård, Knut Tore; Mollnes, Tom Eirik. (2016) The intracellular C5 system is critical to DAMP sensing and cellular responses in human monocytes. Immunobiology
  Abstract
• Pilely, Katrine; Rosbjerg, Anne; Genster, Ninette; Gál, Peter; Pál, Gábor; Halvorsen, Bente. (2016) Cholesterol crystals activate the lectin complement pathway via ficolin-2 and mannose-binding lectin: Implications for the progression of atherosclerosis. Journal of Immunology
  Academic article
• Nymo, Stig Haugset; Gustavsen, Alice; Nilsson, Per; Lau, Corinna; Espevik, Terje; Mollnes, Tom Eirik. (2016) Human endothelial cell activation by Escherichia coli and staphylococcus aureus is mediated by TNF and IL-1β secondarily to activation of C5 and CD14 in whole blood. Journal of Immunology
  Academic article
• Malmo, Jostein; Moe, Nina; Krokstad, Sidsel; Ryan, Liv; Loevenich, Simon; Johnsen, Ingvild Bjellmo. (2016) Cytokine profiles in human metapneumovirus infected children: Identification of genes involved in the antiviral response and pathogenesis. PLOS ONE
  Academic article
• Zimmer, Sebastian; Grebe, Alena; Bakke, Siril Skaret; Bode, Niklas; Halvorsen, Bente; Ulas, Thomas. (2016) Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming. Science Translational Medicine
  Academic article
• Ørning, Mathias Pontus; Hoem, Kine Samset; Coron, Abba Elizabeth; Skjåk-Bræk, Gudmund; Mollnes, Tom Eirik; Brekke, Ole Lars. (2016) Alginate microsphere compositions dictate different mechanisms of complement activation with consequences for cytokine release and leukocyte activation. Journal of Controlled Release
  Academic article
• Kleveland, Ola; Kunszt, Gabor; Bratlie, Marte; Ueland, Thor; Broch, Kaspar; Holte, Espen. (2016) Effect of a single dose of the interleukin-6 receptor antagonist tocilizumab on inflammation and troponin T release in patients with non-ST-elevation myocardial infarction: a double-blind, randomized, placebo-controlled phase 2 trial. European Heart Journal
  Academic article
• Gustavsen, Alice; Nymo, Stig Haugset; Landsem, Anne; Christiansen, Dorte; Ryan, Liv; Husebye, Harald. (2016) Combined inhibition of complement and CD14 attenuates bacteria-induced inflammation in human whole blood more efficiently than antagonizing the toll-like receptor 4-MD2 complex. Journal of Infectious Diseases
  Academic article

2015

• Nilsen, Nadra; Gregory I., Vladimer; Stenvik, Jørgen; Ørning, Mathias Pontus; Zeid-Kilani, Maria Vanessa; Bugge, Marit. (2015) A role for the adaptor proteins TRAM and TRIF in toll-like receptor 2 signaling. Journal of Biological Chemistry
  Academic article
• Sponaas, Anne-Marit; Moen, Siv Helen; Liabakk, Nina-Beate; Feyzi, Emadoldin; Holien, Toril; Kvam, Solveig. (2015) The proportion of CD16+CD14dim monocytes increases with tumor cell load in bone marrow of patients with multiple myeloma. Immunity,Inflammation and Disease
  Academic article
• Hovland, Anders; Jonasson, Lena; Garred, Peter; Yndestad, Arne; Aukrust, Pål; Lappegård, Knut Tore. (2015) The complement system and toll-like receptors as integrated players in the pathophysiology of atherosclerosis. Atherosclerosis
  Academic literature review
• Egge, Kjetil Hagene; Barratt-Due, Andreas; Nymo, Stig Haugset; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Lau, Corinna. (2015) The anti-inflammatory effect of combined complement and CD14 inhibition is preserved during escalating bacterial load. Clinical and Experimental Immunology
  Academic article
• Bergstrøm, Bjarte; Aune, Marie Hjelmseth; Awuh, Jane Atesoh; Kojen, June Frengen; Blix, Kjetil Jordahl; Ryan, Liv. (2015) TLR8 senses Staphylococcus aureus RNA in human primary monocytes and macrophages and induces IFN-β production via a TAK1-IKKβ-IRF5 signaling pathway. Journal of Immunology
  Academic article
• Klein, Dionne; Skjesol, Astrid; Kers-Rebel, Esther D.; Sherstova, Tatyana; Sporsheim, Bjørnar; Egeberg, Kjartan Wøllo. (2015) CD14, TLR4 and TRAM Show Different Trafficking Dynamics During LPS Stimulation. Traffic: The moving front of cell biology
  Academic article
• Niyonzima, Nathalie; Samstad, Eivind; Aune, Marie Hjelmseth; Ryan, Liv; Bakke, Siril Skaret; Rokstad, Anne Mari. (2015) Reconstituted high-density lipoprotein attenuates cholesterol crystal-induced inflammatory responses by reducing complement activation. Journal of Immunology
  Academic article
• Lau, Corinna; Nygård, Ståle; Fure, Hilde; Olstad, Ole Kristoffer; Holden, Marit; Lappegård, Knut Tore. (2015) CD14 and complement crosstalk and largely mediate the transcriptional response to Escherichia coli in human whole blood as revealed by DNA microarray. PLOS ONE
  Academic article
• Lau, Corinna; Olstad, Ole Kristoffer; Holden, Marit; Nygård, Ståle; Fure, Hilde; Lappegård, Knut Tore. (2015) Gene expression profiling of Gram-negative bacteria-induced inflammation in human whole blood: The role of complement and CD14-mediated innate immune response. Genomics Data
  Academic article
• Espevik, Terje. (2015) Reconstituted High-Density Lipoprotein Attenuates Cholesterol Crystal-Induced Inflammatory Responses by Reducing Complement Activation. Journal of Immunology
  Academic article
• Skjeflo, Espen Waage; Sagatun, Caroline; Dybwik, Knut; Aam, Sturla; Urving, Sven Haakon; Nunn, Miles A.. (2015) Combined inhibition of complement and CD14 improved outcome in porcine polymicrobial sepsis. Critical Care
  Academic article

2014

• Samstad, Eivind; Niyonzima, Nathalie; Nymo, Stig Haugset; Aune, Marie Hjelmseth; Ryan, Liv; Bakke, Siril Skaret. (2014) Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release. Journal of Immunology
  Academic article
• Nymo, Stig Haugset; Niyonzima, Nathalie; Espevik, Terje; Mollnes, Tom Eirik. (2014) Cholesterol crystal-induced endothelial cell activation is complement-dependent and mediated by TNF. Immunobiology
  Academic article
• Arlov, Øystein; Aachmann, Finn Lillelund; Sundan, Anders; Espevik, Terje; Skjåk-Bræk, Gudmund. (2014) Heparin-Like Properties of Sulfated Alginates with Defined Sequences and Sulfation Degrees. Biomacromolecules
  Academic article
• Skjeflo, Espen Waage; Christiansen, Dorte; Espevik, Terje; Nielsen, Erik Waage; Mollnes, Tom Eirik. (2014) Combined inhibition of complement and CD14 efficiently attenuated the inflammatory response induced by staphylococcus aureus in a human whole blood model. Journal of Immunology
  Academic article
• Huber-Lang, Markus; Barratt-Due, Andreas; Pischke, Søren Erik; Sandanger, Øystein; Nilsson, Per; Nunn, Miles A.. (2014) Double blockade of CD14 and complement C5 abolishes the cytokine storm and improves morbidity and survival in polymicrobial sepsis in mice. Journal of Immunology
  Academic article
• Lappegård, Knut Tore; Garred, Peter; Jonasson, Lena; Espevik, Terje; Aukrust, Pål; Yndestad, Arne. (2014) A vital role for complement in heart disease. Molecular Immunology
  Academic literature review
• Franklin, Bernardo S; Bossaller, Lukas; De Nardo, Dominic; Ratter, Jacqueline M; Stutz, Andrea; Engels, Gudrun. (2014) The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation. Nature Immunology
  Academic article
• Østvik, Ann Elisabet; Granlund, Atle Van Beelen; Gustafsson, Björn; Torp, Sverre Helge; Espevik, Terje; Mollnes, Tom Eirik. (2014) Mucosal toll-like receptor 3-dependent synthesis of complement factor B and systemic complement activation in inflammatory bowel disease. Inflammatory Bowel Diseases
  Academic article
• Nordgård, Catherine Taylor; Nonstad, Unni; Olderøy, Magnus Østgård; Espevik, Terje; Draget, Kurt Ingar. (2014) Alterations in mucus barrier function and matrix structure induced by guluronate oligomers. Biomacromolecules
  Academic article

2013

• Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Strand, Berit Løkensgard. (2013) The induction of cytokines by polycation containing microspheres by a complement dependent mechanism. Biomaterials
  Academic article
• Granlund, Atle Van Beelen; Flatberg, Arnar; Østvik, Ann Elisabet; Drozdov, Ignat; Gustafsson, Björn; Kidd, Mark. (2013) Whole Genome Gene Expression Meta-Analysis of Inflammatory Bowel Disease Colon Mucosa Demonstrates Lack of Major Differences between Crohn's Disease and Ulcerative Colitis. PLOS ONE
  Academic article
• Sandanger, Øystein; Ranheim, Trine; Vinge, Leif Erik; Bliksøen, Marte; Alfsnes, Katrine; Finsen, Alexandra. (2013) The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury. Cardiovascular Research (CVR)
  Academic article
• Samstad, Eivind; Niyonzima, Nathalie; Nymo, Stig Haugset; Aune, Marie Hjelmseth; Ryan, Liv; Brekke, Ole Lars. (2013) Cholesterol crystals induce inflammasome activation and cytolcine release in a complement-dependent manner. Molecular Immunology
  Abstract
• Rokstad, Anne Mari; Strand, Berit Løkensgard; Espevik, Terje; Mollnes, Tom Eirik. (2013) Biocompatibility and Biotolerability Assessment of Microspheres Using a Whole Blood Model. Micro and Nanosystems
  Academic article
• Mollnes, Tom Eirik; Barratt-Due, Andreas; Pischke, Søren Erik; Sandanger, Inger; Nilsson, Per; Lambris, J. (2013) Double-blockade of CD14 and complement component C5 abolish the inflammatory storm and improve survival in mouse polymicrobial sepsis. Molecular Immunology
  Abstract
• Espevik, Terje. (2013) Sensorer som setter i gang betennelse: hvordan virker de og hvorfor trenger vi dem?. Årbok / Det norske videnskaps-akademi
  Popular scientific article
• Grimstad, Øystein; Husebye, Harald; Espevik, Terje. (2013) TLR3 mediates release of IL-1 beta and cell death in keratinocytes in a caspase-4 dependent manner. Journal of dermatological science (Amsterdam)
  Academic article
• Lau, Corinna; Gunnarsen, Kristin Støen; Høydahl, Lene Støkken; Andersen, Jan Terje; Berntzen, Gøril; Pharo, Anne Margrethe. (2013) Chimeric Anti-CD14 IGG2/4 Hybrid Antibodies for Therapeutic Intervention in Pig and Human Models of Inflammation. Journal of Immunology
  Academic article
• Nymo, Stig Haugset; Samstad, Eivind; Niyonzima, Nathalie; Aune, Marie Hjelmseth; Bergseth, Grete; Ryan, Liv. (2013) Cholesterol crystals activate the complement system and are phagocytosed in a complement-dependent manner. Molecular Immunology
  Abstract
• Espevik, Terje. (2013) CEMIR sitt forskningstema er inflammasjon.
  Website (informational material)
• Espevik, Terje. (2013) CEMIR's research topic is inflammation.
  Website (informational material)
• Hetland, Geir; Tryggestad, Anne Merete Aaland; Espevik, Terje; Ryan, Liv. (2013) The medicinal mushroom Agaricus blazei Murill promotes NF-B activation via stimulation of TLR2 and inhibits its activation via TLR4. Journal of Pharmaceutical and Biomedical Sciences
  Academic article
• Østvik, Ann Elisabet; Granlund, Atle; Bugge, Marit; Nilsen, Nadra; Torp, Sverre Helge; Waldum, Helge. (2013) Enhanced expression of CXCL10 in inflammatory bowel disease: Potential role of mucosal toll-like 3 receptor stimulation. Inflammatory Bowel Diseases
  Academic article
• Østvik, Ann Elisabet; Granlund, Atle Van Beelen; Torp, Sverre Helge; Flatberg, Arnar; Beisvag, Vidar; Waldum, Helge. (2013) Expression of Toll-like receptor-3 is enhanced in active inflammatory bowel disease and mediates the excessive release of lipocalin 2. Clinical and Experimental Immunology
  Academic article

2012

• Stenvik, Jørgen; Sletta, Håvard; Grimstad, Øystein; Pukstad, Brita; Ryan, Liv; Aune, Randi. (2012) Alginates induce differentiation and expression of CXCR7 and CXCL12/SDF-1 in human keratinocytes - the role of calcium. Journal of Biomedical Materials Research. Part A
  Academic article
• Klein, Dionne; Øvrebø, Kirsti Marie; Latz, Eicke; Espevik, Terje; Stokke, Bjørn Torger. (2012) Direct measurement of the interaction force between immunostimulatory CpG-DNA and TLR9 fusion protein. Journal of Molecular Recognition
  Academic article
• Doyle, SL; Husebye, Harald; Connolly, D; Espevik, Terje; O'Neill, LAJ; McGettrick, AF. (2012) The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation. Nature Communications
  Academic article
• Rokstad, Anne Mari; Gustafsson, Björn; Espevik, Terje; Bakke, Ingunn; Pfragner, Roswitha; Svejda, Bernhard. (2012) Microencapsulation of small intestinal neuroendocrine neoplasm cells for tumor model studies. Cancer Science
  Academic article
• Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Lambris, John D.. (2012) Poly-cation containing alginate microcapsules induce cytokines by a complement-dependent mechanism. Immunobiology
  Abstract
• Østvik, Ann Elisabet; Granlund, Atle Van Beelen; Torp, Sverre Helge; Flatberg, Arnar; Waldum, Helge; Espevik, Terje. (2012) Induction of Lipocalin-2 in Colonic Epithelial Cells in Inflammatory Bowel Disease. Inflammatory Bowel Diseases
  Abstract
• Grimstad, Øystein; Pukstad, Brita; Stenvik, Jørgen; Espevik, Terje. (2012) Oligodeoxynucleotides inhibit Toll-like receptor 3 mediated cytotoxicity and CXCL8 release in keratinocytes. Experimental Dermatology
  Academic article
• Lau, Corinna; Gunnarsen, Kristin Støen; Høydahl, Lene Støkken; Berntzen, Gøril; Stokes, Christopher R.; Espevik, Terje. (2012) Recombinant anti-human and anti-porcine CD14 antibodies. Immunobiology
  Abstract
• Niyonzima, Nathalie; Samstad, Eivind; Aune, Marie Hjelmseth; Ryan, Liv; Damås, Jan Kristian; Wright, Samuel. (2012) Complement dependency of cholesterol crystal-induced inflammation - II. Inflammasome activation and regulation mechanisms involving reconstituted high density lipoprotein (HDL) and C-reactive protein (CRP). Immunobiology
  Abstract
• Mollnes, Tom Eirik; Barratt-Due, Andreas; Pischke, Søren Erik; Sandanger, Øystein; Nunn, Miles A.; Espevik, Terje. (2012) The systemic inflammatory reaction in polymicrobial sepsis induced by murine cecal ligation and puncture is equally dependent on C5 and CD14. Immunobiology
  Abstract
• Christiansen, Dorte; Stenvik, Jørgen; Brekke, Ole Lars; Lambris, John D.; Espevik, Terje; Mollnes, Tom Eirik. (2012) Phagocytosis of Escherichia coli in human whole blood: Early complement dependency is succeeded by late CD14 dependency over time. Immunobiology
  Abstract
• Nymo, Stig; Samstad, Eivind; Niyonzima, Nathalie; Bergseth, Grethe; Christiansen, Dorte; Ryan, Liv. (2012) Complement dependency of cholesterol crystal-induced inflammation - I. Pathway activation mechanisms, cytokine responses and endothelial cell activation. Immunobiology
  Abstract
• Skjeflo, Espen; Christiansen, Dorte; Lambris, John D.; Espevik, Terje; Nielsen, Erik Waage; Mollnes, Tom Eirik. (2012) Combined inhibition of complement and CD14 efficiently attenuated the inflammatory response induced by Staphylococcus aureus in a human whole blood model. Immunobiology
  Abstract
• Barratt-Due, Andreas; Pischke, Søren Erik; Brekke, Ole Lars; Thorgersen, Ebbe Billmann; Nielsen, Erik Waage; Espevik, Terje. (2012) Bride and groom in systemic inflammation - The bells ring for complement and Toll in cooperation. Immunobiology
  Academic literature review
• Granlund, Atle; Flatberg, Arnar; Østvik, Ann Elisabet; Drozdov, I; Gustafsson, Björn; Kidd, M. (2012) Dissecting the IBD Transcriptome. Inflammatory Bowel Diseases
  Abstract
• Østvik, Ann Elisabet; Nilsen, Nadra; Granlund, Atle; Torp, Sverre Helge; Flatberg, Arnar; Waldum, Helge. (2012) Enhanced expression of CXCL10 in inflammatory bowel disease-role of mucosal TLR3 stimulation. Journal of Crohn’s and Coltis Supplements
  Abstract
• Christiansen, Dorte; Brekke, Ole Lars; Stenvik, Jørgen; Lambris, J.D.; Espevik, Terje; Mollnes, Tom Eirik. (2012) Differential Effect of Inhibiting MD-2 and CD14 on LPS- Versus Whole E. coli Bacteria-Induced Cytokine Responses in Human Blood. Advances in Experimental Medicine and Biology
  Academic article

2011

• Torgersen, Maria Lyngaas; Engedal, Kim Nikolai; Pedersen, Anne-Mari Gjestvang; Husebye, Harald; Espevik, Terje; Sandvig, Kirsten. (2011) Toll-like receptor 4 facilitates binding of Shiga toxin to colon carcinoma and primary umbilical vein endothelial cells. FEMS Immunology and Medical Microbiology
  Academic article
• Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Strand, Berit Løkensgard. (2011) Alginate microbeads are complement compatible, in contrast to polycation containing microcapsules, as revealed in a human whole blood model. Acta Biomaterialia
  Academic article
• Nørgaard, Nikolai Nordberg; Holien, Toril; Jönsson, S; Hella, Hanne; Espevik, Terje; Sundan, Anders. (2011) CpG-ODN inhibits Smad-dependent BMP signaling; Effects on myeloma cell apoptosis and in vitro osteoblastogenesis. Bone
  Abstract
• Grimstad, Øystein; Sandanger, Øystein; Ryan, Liv; Otterdal, Kari; Damås, Jan Kristian; Pukstad, Brita. (2011) Cellular sources and inducers of cytokines present in acute wound fluid. Wound Repair and Regeneration
  Academic article

2010

• Grimstad, Øystein; Pukstad, Brita; Stenvik, Jørgen; Espevik, Terje. (2010) TLR3 mediated cytotoxicity in keratinocytes is inhibited by co-stimulation with oligodeoxynucleotides. Journal of Investigative Dermatology
  Abstract
• Hetland, Geir; Tryggestad, Anne Merete Aaland; Espevik, Terje; Ryan, Liv; Tangen, Jon-Magnus; Johnson, Egil. (2010) The Medicinal and Antitumor Mushroom, Agaricus Blazei Murill, Activates NF-kappa B Via TLR2 but Not TLR4 In Monocytic Cells, and Stimulates Monocyte-Derived Dendritic Cells (MDDC) to Increased Cell Surface Marker Expression and Cytokine Production, and May Thus Have Adjuvant Effect In MDDC Cancer Vaccines. Blood
  Abstract
• Hetland, Geir; Tryggestad, Anne Merete Aaland; Espevik, Terje; Ryan, Liv; Tangen, Jon-Magnus; Johnson, Egil. (2010) The medicinal and antitumour mushroom, agaricus blazei murill, activates NF-KB via TLR2 in monocytic cells and induces expression of cell surface markers and production of cytokines in human monocyte-derived dendritic cells (MDDC) in vitro. European Journal of Cancer
  Abstract
• Husebye, Harald; Aune, Marie Hjelmseth; Stenvik, Jørgen; Samstad, Eivind Ottersen; Skjeldal, Frode Miltzow; Halaas, Øyvind. (2010) The Rab11a GTPase Controls Toll-like Receptor 4-Induced Activation of Interferon Regulatory Factor-3 on Phagosomes. Immunity
  Academic article
• Christiansen, D; Brekke, Ole Lars; Stenvik, Jørgen; Lambris, JD; Espevik, Terje; Mollnes, Tom Eirik. (2010) Differential effect of inhibiting MD-2 and CD14 on LPS- versus whole E. coli bacteria-induced cytokine responses in human blood. Molecular Immunology
  Abstract
• Nilsen, Asbjørn Magne; Vik, Randi; Behrens, Carl; Drabløs, Per Arne; Espevik, Terje. (2010) Beryllium Sensitivity Among Workers at a Norwegian Aluminum Smelter. American Journal of Industrial Medicine
  Academic article
• Salvesen, Bodil; Stenvik, Jørgen; Rosetti, Carlo; Saugstad, Ola D; Espevik, Terje; Mollnes, Tom E.. (2010) Meconium-induced release of cytokines is mediated by the TRL4/MD-2 complex in a CD14-dependent manner. Molecular Immunology
  Academic article
• Halaas, Øyvind; Steigedal, Magnus; Haug, Markus; Awuh, Jane Atesoh; Ryan, Liv; Brech, Andreas. (2010) Intracellular Mycobacterium avium Intersect Transferrin in the Rab11(+) Recycling Endocytic Pathway and Avoid Lipocalin 2 Trafficking to the Lysosomal Pathway. Journal of Infectious Diseases
  Academic article
• Etokebe, GE; Skjeldal, F; Nilsen, Nadra; Rodionov, Dmitrii; Knezevic, Jelena; Bulat-Kardum, Ljiljana. (2010) Toll-Like Receptor 2 (P631H) Mutant Impairs Membrane Internalization and is a Dominant Negative Allele. Scandinavian Journal of Immunology
  Academic article
• Duewell, P; Kono, H; Rayner, KJ; Sirois, CM; Vladimer, G; Bauernfeind, FG. (2010) NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature
  Academic article
• Pukstad, Brita; Ryan, Liv; Flo, Trude Helen; Stenvik, Jørgen; Moseley, Ryan; Harding, Keith. (2010) Non-healing is associated with persistent stimulation of the innate immune response in chronic venous leg ulcers. Journal of dermatological science (Amsterdam)
  Academic article
• Klein, Dionne C.G.; Latz, Eicke; Espevik, Terje; Stokke, Bjørn Torger. (2010) Higher order structure of short immunostimulatory oligonucleotides studied by atomic force microscopy. Ultramicroscopy
  Academic article
• Nørgaard, Nikolai Nordberg; Holien, Toril; Jonsson, Sofia; Hella, Hanne; Espevik, Terje; Sundan, Anders. (2010) CpG-Oligodeoxynucleotide Inhibits Smad-Dependent Bone Morphogenetic Protein Signaling: Effects on Myeloma Cell Apoptosis and In Vitro Osteoblastogenesis. Journal of Immunology
  Academic article

2009

• Standal, Therese; Norgaard, NN; Bohnhorst, J; Espevik, T; Waage, A; Sundan, A. (2009) Does Toll-like Receptor 9 Signaling Play a Role in Myeloma Disease Progression?. Clinical Lymphoma & Myeloma
  Abstract
• Espevik, Terje; Rokstad, Anne Mari; Kulseng, Bård Eirik; Strand, Berit Løkensgard; Skjåk-Bræk, Gudmund. (2009) Mechanisms of the host immune response to alginate microcapsules.
  Chapter
• Sandanger, Øystein; Sandanger, O; Ryan, Liv; Bohnhorst, Janne Øvrebø; Iversen, Ann-Charlotte; Iversen, AC. (2009) IL-10 Enhances MD-2 and CD14 Expression in Monocytes and the Proteins Are Increased and Correlated in HIV-Infected Patients. Journal of Immunology
  Academic article
• Yndestad, A; Landrø, Linn; Ueland, Thor; Dahl, CP; Flo, Trude Helen; Vinge, Leif Erik. (2009) Increased systemic and myocardial expression of neutrophil gelatinase-associated lipocalin in clinical and experimental heart failure. European Heart Journal
  Academic article
• Damås, Jan Kristian; Davi, Giovanni; Jensenius, M; Santilli, F; Otterdal, K; Ueland, T. (2009) Relative chemokine and adhesion molecule expression in Mediterranean spotted fever and African tick bite fever. Journal of Infection
  Academic article
• Palsson-McDermott, EM; Doyle, SL; McGettrick, AF; Hardy, M; Husebye, Harald; Banahan, K. (2009) TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway. Nature Immunology
  Academic article
• Iversen, Ann-Charlotte; Steinkjer, Bjørg; Nilsen, Nadra; Bohnhorst, Janne Øvrebø; Moen, Siv Helen; Vik, Randi. (2009) A proviral role for CpG in cytomegalovirus infection. Journal of Immunology
  Academic article
• Castellheim, A; Brekke, Ole Lars; Espevik, T; Harboe, M; Harboe, M; Mollnes, Tom Eirik. (2009) Innate Immune Responses to Danger Signals in Systemic Inflammatory Response Syndrome and Sepsis. Scandinavian Journal of Immunology
  Academic literature review

2008

• Hetland, G; Tryggestad, AMA; Forland, T; Johnson, E; Ryan, L; Espevik, Terje. (2008) Proposed immunomodulatory co-therapy for hematological cancer by the medicinal mushroom Agaricus blazei Murill, is facilitated by its stimulation of TLR2 and activation of NF-KB. Vox Sanguinis
  Abstract
• Klein, Dionne C.G.; Latz, Eicke; Espevik, Terje; Stokke, Bjørn Torger. (2008) Effects of CpG-DNA on Toll-like receptor 9 studied by AFM. TRAUNER Verlag TRAUNER Verlag
  Academic anthology/Conference proceedings
• Halaas, Øyvind; Husebye, Harald; Stenmark, Harald; Espevik, Terje. (2008) Intracellular Trafficing of Toll-like Receptors. CRC Press
  Academic chapter/article/Conference paper
• Landrø, Linn Aina Ysland; Landro, L; Damås, Jan Kristian; Damas, JK; Flo, Trude Helen; Heggelund, L. (2008) Decreased serum lipocalin-2 levels in human immunodeficiency virus-infected patients: increase during highly active anti-retroviral therapy. Clinical and Experimental Immunology
  Academic article
• Hellerud, BC; Stenvik, Jørgen; Espevik, Terje; Lambris, John D.; Mollnes, Tom Eirik; Brandtzaeg, P. (2008) Stages of meningococcal sepsis stimulated in vitro, with emphasis on complement and Toll-like receptor activation. Infection and Immunity
  Academic article
• Nilsen, Nadra; Deininger, S; Nonstad, Unni; Skjeldal, F; Husebye, Harald; Rodionov, D. (2008) Cellular trafficking of lipoteichoic acid and Toll-like receptor 2 in relation to signaling; role of CD14 and CD36. Journal of Leukocyte Biology
  Academic article
• Hellerud, BC; Stenvik, Jørgen; Espevik, Terje; Lambris, JD; Mollnes, TE; Brandtzæg, Petter. (2008) Stages of meningococcal sepsis simulated in vitro, with emphasis on complement and Toll-like receptor activation. Infection and Immunity
  Academic article
• Mollnes, Tom Eirik; Christiansen, D; Brekke, Ole Lars; Espevik, T. (2008) Hypothesis: Combined inhibition of complement and CD14 as treatment regimen to attenuate the inflammatory response. Advances in Experimental Medicine and Biology
  Academic article
• Nilsen, Nadra; Espevik, Terje; Lien, Egil. (2008) Toll-like receptor 2 expression, regulation and signaling. Tapir Akademisk Forlag Tapir Akademisk Forlag
  Doctoral dissertation

2007

• Latz, E; Verma, Anjali; Visintin, A; Gong, Mei; Sirois, CM; Klein, Dionne. (2007) Corrigendum: Ligand-induced conformational changes allosterically activate Toll-like receptor 9. International Immunology
  Academic article
• Halaas, Øyvind; Husebye, Harald; Espevik, Terje. (2007) The journey of Toll-like receptors in the cell. Advances in Experimental Medicine and Biology
  Academic article
• Tunheim, G; Thompson, KM; Fredriksen, AB; Espevik, Terje; Schjetne, KW; Bogen, B. (2007) Human receptors of innate immunity (CD14, TLR2) are promising targets for novel recombinant immunoglobulin-based vaccine candidates. Vaccine
  Academic article
• Latz, Eicke; Verma, Anjali; Visintin, A; Gong, Mei; Sirois, Cherilyn m.; Klein, Dionne. (2007) Ligand-induced conformational changes allosterically activate Toll-like receptor 9. Nature Immunology
  Academic article

2006

• Espevik, Terje; Skjåk-Bræk, Gudmund. (2006) Friskere fisk med tang og tare. Gemini
  Popular scientific article
• Espevik, Terje; Lien, Egil. (2006) Vaksine mot svartedauen. Gemini
  Popular scientific article
• Nilsen, Asbjørn Magne; Vik, Randi; Espevik, Terje. (2006) Be-LPT testing Karmøy. Undervegsrapport 4. April 2006. Norges Teknisk-Naturvitenskapelige Universitet
  Report
• Nilsen, Asbjørn Magne; Vik, Randi; Espevik, Terje. (2006) Be-LPT testing Karmøy. Undervegsrapport 3. Mars 2006. Norges Teknisk-Naturvitenskapelige Universitet
  Report
• Nilsen, Asbjørn Magne; Vik, Randi; Espevik, Terje. (2006) Be-LPT testing at Hydro Aluminium Karmøy AS. Final Report. June 2006. Norwegian University of Science and Technology
  Report
• Nilsen, Asbjørn Magne; Vik, Randi; Espevik, Terje. (2006) BeLPT testing Karmøy. Undervegsrapport 1. Januar 2006. Norges Teknisk-Naturvitenskapelige Universitet
  Report
• Nilsen, Asbjørn Magne; Vik, Randi; Espevik, Terje. (2006) Be-LPT testing Karmøy. Undervegsrapport 2. Februar 2006. Norges Teknisk-Naturvitenskapelige Universitet
  Report
• Ueland, Thor; Espevik, Terje; Kjekshus, John; Gullestad, Lars; Omland, Torbjørn; Squire, Iain B.. (2006) Mannose binding lectin and soluble Toll-lilke receptor 2 in heart failure following acute myocardial infarction. Journal of Cardiac Failure
  Academic article
• Bohnhorst, Janne Øvrebø; Rasmussen, T; Moen, Siv H; Fløttum, Marianne; Knudsen, L; Børset, Magne. (2006) Toll-like receptors mediate proliferation and survival of multiple myeloma cells. Leukemia
  Academic article
• Johnsen, Ingvild Bjellmo; Nguyen, Thank Thuy Thi; Ringdal, Monika; Tryggestad, AM; Bakke, Oddmund; Lien, Egil. (2006) Toll-like receptor 3 associates with c-Src tyrosine kinase on endosomes to initiate antiviral signaling. EMBO Journal
  Academic article
• Rokstad, Anne Mari Aukan; Donati, Ivan; Borgogna, Massimiliano; Oberholzer, José; Strand, Berit Løkensgard; Espevik, Terje. (2006) Cell-compatible covalently reinforced beads obtained from a chemoenzymatically engineered alginate. Biomaterials
  Academic article
• Husebye, Harald; Halaas, Øyvind; Stenmark, Harald; Tunheim, G; Sandanger, Øystein; Bogen, B. (2006) Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity. EMBO Journal
  Academic article

2005

• Rokstad, Anne Mari Aukan; Bjerkvig, Rolf; Espevik, Terje; Lund-Johansen, M. (2005) Applications of Cell Immobilisation Biotechnology, Focus on Biotechnology. Book chapter: Cell encapsulation therapy for malignant gliomas. Springer Springer
  Academic anthology/Conference proceedings
• Heggelund, L; Mollnes, TE; Espevik, Terje; Muller, F; Kristiansen, KI; Aukrust, P. (2005) Modulatory effect of mannose-binding lectin on cytokine resposes: possible roles in HIV infection. European Journal of Clinical Investigation
  Academic article
• Heggelund, Lars; Mollnes, Tom Eirik; Espevik, Terje; Muller, Fredrik; Kristiansen, Knut Ivan; Aukrust, Pål. (2005) Modulatory effect of mannose-binding lectin on cytokine responses: possible roles in HIV infection. European Journal of Clinical Investigation
  Academic article
• Mancuso, Guiseppe; Midiri, A; Biondo, Carmelo; Beninati, C.; Gambuzza, M; Macri, D. (2005) Bacteroides fragilis-derived lipopolysaccharide produces cell activation and lethal toxicity via toll-like receptor 4. Infection and Immunity
  Academic article
• Manukyan, M; Triantafilou, K; Triantafilou, M; Mackie, A; Nilsen, Nadra Jesmine; Espevik, Terje. (2005) Binding of lipopeptide to CD14 induces physical proximity of CD14, TLR2 and TLR1. European Journal of Immunology
  Academic article
• Dybdahl, Brit; Slørdahl, Stig Arild; Waage, Anders; Kierulf, Peter; Espevik, Terje; Sundan, Anders. (2005) Myocardial ischaemia and the inflammatory response: release of heat shock protein 70 after myocardial infarction. Heart
  Academic article
• Heggelund, L; Mollnes, TE; Espevik, Terje; Muller, F; Kristiansen, KI; Aukrust, P. (2005) Modulatory effect of mannose-binding lectin on cytokine responses: roles in HIV infection. European Journal of Clinical Investigation
  Academic article

2004

• Halaas, Øyvind; Liabakk, Nina-Beate; Vik, Randi; Beninati, C; Henneke, P; Sundan, Anders. (2004) Monocytes stimulated with group B Streptococci or interferons release tumour necrosis factor-related apoptosis-inducing ligand. Scandinavian Journal of Immunology
  Academic article
• Nilsen, N; Nonstad, U; Khan, N; Knetter, Cathrine; Akira, S; Sundan, Anders. (2004) Lipopolysaccharide and double-stranded RNA up-regulate toll-like receptor 2 independently of myeloid differentiation factor 88. Journal of Biological Chemistry
  Academic article
• Heggelund, L; Flo, Trude Helen; Berg, K.; Lien, E; Espevik, Terje. (2004) Soluble toll-like receptor 2 in HIV infection: association with disease progression. AIDS (London)
  Academic article
• Heggelund, Lars; Flo, T; Berg, K; Lien, T; Mollnes, TE; Ueland, Thor. (2004) Soluble toll-like receptor 2 in HIV infection: association with disease progression. AIDS (London)
  Academic article
• Dybdahl, Brit; Wahba, Alexander; Haaverstad, R; Kirkeby-Garstad, Idar; Kierulf, Peter; Espevik, Terje. (2004) On-pump versus off-pump coronary artery bypass grafting: more heat-shock protein 70 is released after on-pump surgery. European Journal of Cardio-Thoracic Surgery
  Academic article
• Frantisek, S; Latz, E; Re, F; Mandell, L; Repik, G; Golenbock, D. (2004) Importance of extra-and intracellular domains of TLR1 and TLR2 receptors in NF-kappa B signaling. Tissue Antigens
  Abstract
• Liabakk, Nina-Beate; Espevik, Terje. (2004) Monoclonal antibodies against TRAIL. Vitamines and Hormones
  Academic article
• Latz, E; Visintin, A; Espevik, Terje; Golenbock, DT. (2004) Mechanisms of TLR9 activation. Journal of Endotoxin Research
  Academic article
• Heggelund, L; Muller, F; Lien, E; Yndestad, A; Ueland, T; Kristiansen, KI. (2004) Increased expression of Toll-like receptor 2 on monocytes in HIV infection: Possible roles in inflammation and viral replication. Clinical Infectious Diseases
  Academic article
• Dybdahl, Brit; Wahba, Alexander; Haaverstad, Rune; Kirkeby-Garstad, I.; Kierulf, P; Espevik, Terje. (2004) On-pump versus off-pump coronary artery bypass grafting: more heat-shock protein 70 is released after on-pump surgery. European Journal of Cardio-Thoracic Surgery
  Academic article
• Espevik, Terje. (2004) Tolerance induced by the lipopeptide Pam3Cys is due to ablation of IL-1R-associated kinase-1. Journal of Immunology
  Academic article
• Latz, E; Schoenemeyer, A; Visintin, A; Fitzgerald, KA; Monks, BG; Knetter, Cathrine. (2004) TLR9 signals after translocating from the ER to CpG DNA in the lysosome. Nature Immunology
  Academic article
• Heggelund, L; Damås, Jan Kristian; Damas, JK; Yndestad, A; Holm, AM; Muller, F. (2004) Stimulation of toll-like receptor 2 in mononuclear cells from HIV-infected patients induces chemokine responses: possible pathogenic consequences. Clinical and Experimental Immunology
  Academic article
• Nilsen, Nadra; Nonstad, Unni; Kahn, Naseema; Knetter, Cathrine; Akira, Shizuo; Sundan, Anders. (2004) Lipopolysaccharide and Double-stranded RNA Up-regulate Toll-like Receptor 2 Independently of Myeloid Differentiation Factor 88. Journal of Biological Chemistry
  Academic article

2003

• Schjetne, KW; Thompson, Keith; Fleckenstein, Burkhard; Aarvak, Tanja; Flo, T. H.; Iversen, Jens Gustav. (2003) Cutting edge: Link between innate and adaptive immunity: toll like receptor 2 (TLR 2) captures antigen for MHC class II presentation to CD4+ T cell responses. Journal of Immunology
  Academic article
• Espevik, Terje; Latz, Eicke; Lien, Egil; Monks, Brian G.. (2003) Cell distribution and functions of Toll-like receptor 4 studied by fluorescent gene constructs. Scandinavian Journal of Infectious Diseases
  Academic article
• Visintin, A; Latz, Eicke; Monks, Brian G.; Espevik, Terje; Golenbock, Douglas T.. (2003) Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction. Journal of Biological Chemistry
  Academic article
• Schjetne, KW; Thompson, KM; Nilsen, Nadra; Flo, Trude Helen; Fleckenstein, B; Iversen, JG. (2003) Cutting edge: link between innate and adaptive immunity: Toll-like receptor 2 internalizes antigen for presentation to CD4+ T cells and could be an efficient vaccine target. Journal of Immunology
  Academic article
• Sandor, F; Latz, Eicke; Mandell, L; Repik, G; Golenbock, Douglas T.; Espevik, Terje. (2003) Importance of extra- and intracellular domains of TLR1 and TLR2 in NFkappa B signaling. Journal of Cell Biology
  Academic article
• Rokstad, Anne Mari Aukan; Strand, Berit Løkensgard; Rian, K.; Steinkjer, Bjørg; Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund. (2003) Evaluation of different types of alginate microcapsules as bioreactors for producing endostatin. Cell Transplantation
  Academic article
• Adib-Conquy, M; Moine, P; Asehnoune, K; Edouard, A; Espevik, Terje; Miyake, K. (2003) Toll-like receptor-mediated tumor necrosis factor and interleukin-10 production differ during systemic inflammation. American Journal of Respiratory and Critical Care Medicine
  Academic article
• Strand, Berit Løkensgard; Mørch, Yrr Asbjørg; Espevik, Terje; Skjåk-Bræk, Gudmund. (2003) Visualization of alginate-poly-L-lysine-alginate microcapsules by confocal laser scanning microscopy. Biotechnology and Bioengineering
  Academic article
• Strand, Berit Løkensgard; Mørch, Yrr Asbjørg; Syvertsen, Kjersti R.; Espevik, Terje; Skjåk-Bræk, Gudmund. (2003) Microcapsules made by enzymatically tailored alginate. Journal of Biomedical Materials Research
  Academic article
• Latz, E; Visintin, A; Lien, E; Fitzgerald, KA; Espevik, Terje; Golenbock, DT. (2003) The LPS receptor generates inflammatory signals from the cell surface. Journal of Endotoxin Research
  Academic article
• Mori, Y; Yoshimura, A; Ukai, T; Lien, Egil; Espevik, Terje; Hara, Y. (2003) Immunohistochemical localization of Toll-like receptors 2 and 4 in gingival tissue from patients with periodontitis. Oral Microbiology and Immunology
  Academic article

2002

• Espevik, Terje. (2002) På väg att knäcka hjärntumörer. Länstidningen, Østersund, Sverige
  Feature article
• Strand, Berit Løkensgard; Gåserød, Olav; Kulseng, Bård Eirik; Espevik, Terje; Skjåk-Bræk, Gudmund. (2002) Alginate-polylysine-alginate microcapsules – effect of size reduction on capsule properties. Journal of Microencapsulation
  Academic article
• Ellingsen, E.A.; Morath, S; Flo, Trude Helen; Schromm, Andra; Hartung, T; Thiemermann, C. (2002) Induction of cytokine production in human T cells and monocytes by highly purified lipoteichoic acid: involvement of Toll-like receptors and CD14. Medical Science Monitor
  Academic article
• Latz, Eicke; Visintin, A; Lien, Egil; Fitzgerald, KA; Monks, Brian G.; Kurt-Jones, EA. (2002) Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the Toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction. Journal of Biological Chemistry
  Academic article
• Belge, KU; Dayyani, F; Horelt, A; Siedlar, M; Frankenberger, M; Frankenberger, B. (2002) The proinflammatory CD14+CD16+DR++ monocytes are a major source of TNF. Journal of Immunology
  Academic article
• Tamai, Riyoko; Sakuta, T; Matsushita, K; Torii, M; Takeuchi, Osamu; Akira, Shizuo. (2002) Human gingival CD14(+) fibroblasts primed with gamma interferon increase production of interleukin-8 in response to lipopolysaccharide through up-regulation of membrane CD14 and MyD88 mRNA expression. Infection and Immunity
  Academic article
• Dybdahl, Brit; Wahba, Alexander; Lien, Egil; Flo, Trude Helen; Waage, Anders; Sellevold, Olav F Münter. (2002) Inflammatory response after open heart surgery: release of heat-shock protein 70 and signaling through toll-like receptor-4. Circulation
  Academic article
• van der Kleij, D; Latz, Eicke; Brouwers, JF; Kruize, YC; Schmitz, M; Kurt-Jones, EA. (2002) A novel host-parasite lipid cross-talk. Schistosomal lyso-phosphatidylserine activates Toll-like recepytor 2 and affects immune polarization. Journal of Biological Chemistry
  Academic article
• Liabakk, Nina-Beate; Sundan, Anders; Torp, Sverre Helge; Aukrust, Pål; Frøland, Stig Sophus; Espevik, Terje. (2002) Development, characterization and use of monoclonal antibodies against sTRAIL measurement of sTRAIL by ELISA. Journal of Immunological Methods (JIM)
  Academic article
• Dybdahl, Brit; Lien, Egil; Flo, Trude Helen; Espevik, Terje; Sundan, Anders; Wahba, Alexander. (2002) Heat Shock Proteins and Endotoxin Combined as a Trigger for Inflammatory Cytokine Release During Cardiopulmonary Bypass: A Possible Third Way? Letter til artikkel. Circulation
  Academic article
• Flo, Trude Helen; Ryan, Liv; Latz, Eicke; Takeuchi, Osamu; Monks, Brian G.; Lien, Egil. (2002) Involvement of toll-like receptor (TLR) 2 and TLR4 in cell activation by mannuronic acid polymers. Journal of Biological Chemistry
  Academic article
• Rokstad, Anne Mari Aukan; Holtan, Synnøve; Strand, Berit Løkensgard; Steinkjer, Bjørg; Ryan, Liv; Kulseng, Bård Eirik. (2002) Microencapsulation of cells producing therapeutic proteins: Optimizing cell growth and secretion. Cell Transplantation
  Academic article

2001

• Jenssen, Jon A; Espevik, Terje. (2001) Cellebiologisk metode for å påvise biologisk aktivitet av svevestøv. SINTEF Rapport
  Report
• Iversen, Ann-Charlotte; Sundan, Anders; Espevik, Terje. (2001) IFN-alpha(2b) and IFN-beta induce TRAIL-mediated NK cell cytotoxicity. The FASEB Journal
  Abstract
• Henneke, Philipp; Takeuchi, Osamu; van Strijp, JA; Guttormsen, HK; Smith, JA; Schromm, Andra. (2001) Novel engagement of CD14 and multiple toll-like receptors by group B streptococci. Journal of Immunology
  Academic article
• Liabakk, Nina-Beate; Waage, Anders; Lien, Egil; Stenvik, Jørgen; Espevik, Terje. (2001) Cytokine bioassays. Methods in Molecular Medicine
  Academic article
• Flo, Trude Helen; Ryan, Liv; Kilaas, L; Skjåk-Bræk, Gudmund; Ingalls, Robin; Sundan, Anders. (2001) The involvement of CD14 and beta2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers. Infection and Immunity
  Academic article
• Wang, J; Warris, A; Ellingsen, E.A.; Jorgensen, P.F.; Flo, Trude Helen; Espevik, Terje. (2001) Involvement of CD14 and toll-like receptors in activation of human monocytes by Aspergillus fumigatus hyphae. Infection and Immunity
  Academic article
• Liabakk, Nina-Beate; Sundan, Anders; Torp, Sverre Helge; Aukrust, Pål; Frøland, Stig; Espevik, Terje. (2001) Development, characterization and use of monclonal antibodies against Strail: Measurement of Strail by Elisa. Journal of Immunological Methods (JIM)
  Academic article
• Strand, Berit Løkensgard; Ryan, Liv; Int Veld, Peter; Kulseng, Bård Eirik; Rokstad, Anne Mari Aukan; Skjåk-Bræk, Gudmund. (2001) Poly-L-Lysine Induces Fibrosis on Alginate Microcapsules via the Induction of Cytokines. Cell Transplantation
  Academic article
• Flo, Trude Helen; Halaas, Øyvind; Torp, Sverre Helge; Ryan, Liv; Lien, Egil; Dybdahl, Brit. (2001) Differential expression of Toll-like receptor 2 in human cells. Journal of Leukocyte Biology
  Academic article
• Lien, Egil; Chow, Jesse C.; Hawkins, Lynn D.; McGuinness, Pamela D.; Miyake, Kensuke; Espevik, Terje. (2001) A novel synthetic acyclic lipid A-like agonist activates cells via the lipopolysaccharide/Toll-like receptor 4 signaling pathway. Journal of Biological Chemistry
  Academic article
• Sugawara, Shunji; Yang, Shuhua; Iki, Koichi; Hatakeyama, Junko; Tamai, Riyoko; Takeuchi, Osamu. (2001) Monocytic cell activation by nonendotoxic glycoprotein from Prevotella intermedia ATCC 25611 is mediated by Toll-like receptor 2. Infection and Immunity
  Academic article
• Rokstad, Anne Mari Aukan; Kulseng, Bård Eirik; Strand, Berit Løkensgard; Skjåk-Bræk, Gudmund; Espevik, Terje. (2001) Transplantation of alginate microcapsules with proliferating cells in mice. Capsular overgrowth and suvival of encapsulated cells of mice and human origin. Annals of the New York Academy of Sciences
  Academic article

2000

• Lien, E.; Espevik, Terje. (2000) Toll-lignende reseptorer - kroppens sensorer for infeksjon. NBS-nytt
  Popular scientific article
• Espevik, Terje; Waage, Anders; Sundan, A.. (2000) Summary of the 8 th International TNF Congress. Trondheim. NBS-nytt
  Non-fiction book
• Espevik, Terje; Waage, Anders; Sundan, Anders. (2000) Summary of the 8th International TNF Congress, Trondheim, May 14-18, 2000. NBS-nytt
  Report
• Cuzzola, Maria; Mancuso, Guiseppe; Beninati, Concetta; Biondo, Carmelo; von Hunolstein, Christina; Orefici, Graziella. (2000) Human monocyte receptors involved in tumor necrosis factor responses to group B streptococcal products. Infection and Immunity
  Academic article
• Flo, Trude Helen; Ryan, Liv; Kilaas, Lars; Skjåk-Bræk, Gudmund; Ingalls, Robin R.A; Sundan, Anders. (2000) Involvement of CD14 and _B2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers. Infection and Immunity
  Academic article
• Cuzzola, M.; Mancuso, G.; Beninati, C.; Biondo, C.; Genovese, F.; Tomasello, F.. (2000) _B2 integrins are involved in cytokine responses to whole gram-positive bacteria. Journal of Immunology
  Academic article
• Falch, Berit H.; Espevik, Terje; Ryan, Liv; Stokke, Bjørn Torger. (2000) The cytokine stimulating activity of (1->3)-_B-D-glucans is dependent on the triple helix conformation. Carbohydrate Research
  Academic article
• Flo, T.H.; Ryan, L.; Kilaas, L.; Skjåk-Bræk, Gudmund; Ingalls, R.R.; Sundan, A.. (2000) Involvement of CD14 and beta2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers. Infection and Immunity
  Academic article
• Skjåk-Bræk, Gudmund; Flo, Trude Helen; Halaas, Øyvind; Espevik, Terje. (2000) Immune stimulating properties of di-equatorially beta(1->4) linked poly-uronides. Proceedings of the Phytochemical Society of Europe
  Academic article
• Flo, Trude Helen; Halaas, Øyvind; Lien, Egil; Ryan, Liv; Teti, Guiseppe; Golenbock, Douglas T.. (2000) Human Toll-like Receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide. Journal of Immunology
  Academic article

1999

• Johnsen, A-C; Steinkjer, B; Egeberg, Kathrine; Sundan, A; Espevik, Terje. (1999) The role of international-2 in regulation the sensitivity of natural killer celler for Fas-mediated apoptosis. European Journal of Haematology
  Academic article
• Lien, E; Nonstad, Unni; Sundan, A; Espevik, Terje. (1999) Polymorphonuchlear of Fas and Fas-Ligand expression in NK cells by cytokines and the involved of Fas-Ligand in NK/LAK cell-mediated cytotoxicity. Cytokine
  Academic article
• Haux, Johan; Iversen, Ann-Charlotte; Johnsen, Ann-Charlotte; Steinkjer, Bjørg; Egeberg, Kjartan Wøllo; Sundan, Anders. (1999) The role of IL-2 in regulating the sensitivity of NK cells for Fas-mediated apoptosis. Cancer Immunology and Immunotherapy
  Academic article
• Iversen, Ann-Charlotte; Johnsen, Ann-Charlotte; Haux, Johan; Steinkjer, Bjørg; Nonstad, Unni; Egeberg, Kjartan Wøllo. (1999) Regulation of Apo-2 Ligand/Trail expression in NK cells - Involvement in NK cell mediated cytotoxicity. Cytokine
  Academic article
• Aukrust, Pål; Müller, Fredrik; Lien, Egil; Nordøy, Ingvild; Liabakk, Nina-Beate; Kvale, Dag. (1999) Tumor necrosis factor (TNF) system levels in human immunodificiency virus-infected patients during highly active antiretroviral therapy: Perisistent TNF activation is associated with virologic and immunologic treatment failure. Journal of Infectious Diseases
  Academic article
• Lien, Egil; Sellati, Timothy J.; Yoshimura, Atsutosi; Flo, Trude Helen; Rawadi, Georges; Finberg, Robert W.. (1999) Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products. Journal of Biological Chemistry
  Academic article
• Johnsen, Ann-Charlotte; Haux, Johan; Steinkjer, Bjørg; Nonstad, Unni; Egeberg, Kjartan Wøllo; Sundan, Anders. (1999) Regulation of APO-2 ligand /Trail expression in NK cells - involvement in NK cell-mediated cytotoxicity. Cytokine
  Academic article
• Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund; Ryan, Liv; Andersson, Arne; King, Aileen; Faxvaag, Arild. (1999) Transplantation of alginate microcapsules. Transplantation
  Academic article
• Kulseng, Bård Eirik; Espevik, Terje; Skjåk-Bræk, Gudmund. (1999) Behandling av diabetes mellitus med transplantasjon av immunbeskyttet øyvev fra pancreas. Tidsskrift for Den norske legeforening
  Academic article
• Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund; Ryan, Liv; Andersson, Arne; King, Aileen; Faxvaag, Arild. (1999) Transplantation of alginate microcapsules. Generation of antibodies against alginates and encapsulated porcine islet-like cell clusters. Transplantation
  Academic article
• Heine, Holger; Delude, Russell L.; Monks, Biran G.; Espevik, Terje; Golenbock, Douglas T.. (1999) Bacterial lipopolysaccharide induces expression of the stress response genes Hop and H411. Journal of Biological Chemistry
  Academic article
• Kulseng, Bård Eirik; Vatten, Lars Johan; Espevik, Terje. (1999) Soluble tumor necrosis factor receptors in sera from patients with insulin-dependent diabetes mellitus: relations to duration and complications of disease. Acta Dermato-Venereologica
  Academic article
• Aukrust, Pål; Haug, Charlotte J.; Ueland, Thor; Lien, Egil; Müller, Fredrik; Espevik, Terje. (1999) Decreased bone formative and enhanced resorptive markers in human immunodeficiency virus infection: Indication of normalization of the bone-remodeling process during highly active antiretroviral therapy. Journal of Clinical Endocrinology and Metabolism (JCEM)
  Academic article
• Børset, Magne; Hjort-Hansen, Henrik; Johnsen, Ann-Charlotte; Seidel, Carina; Waage, Anders; Espevik, Terje. (1999) Apoptosis, proliferation and NF-k(kappa)B activation induced by agonistic Fas antibodies in the human myeloma cell line OH-2: amplification of Fas-mediated apoptosis by tumor necrosis factor. European Journal of Haematology
  Academic article
• Gullestad, Lars; Aukrust, Pål; Ueland, Thor; Espevik, T; Yee, G.; Vagelos, R.. (1999) Effect of high- versus low-dose angiotensin converting enzyme inhibition on cytokine levels in chronic heart failure. Journal of the American College of Cardiology
  Academic article
• Aukrust, Pål; Muller, Fredrik; Lien, Egil; Nordøy, Ingvild; Liabakk, Nina-Beate; Kvale, Dag. (1999) Tumor necrosis factor (TNF) system in human immunodeficiency virus-infected patients during highly active antiretroviral therapy (HAART): Persistent TNF activation is associated with virologic and immunologic treatment failure. Journal of Infectious Diseases
  Academic article
• Aukrust, Pål; Haug, Charlotte J.; Ueland, Thor; Lien, Egil; Muller, Fredrik; Espevik, T. (1999) Decreased bone formative and enhanced resorptive markers in human immunodeficiency virus infection: indication of normalization of the bone-remodeling process during highly active antiretroviral therapy. Journal of Clinical Endocrinology and Metabolism (JCEM)
  Academic article
• Aukrust, Pål; Ueland, Thor; Lien, Egil; Bendtzen, Klaus; Muller, Fredrik; Andreassen, Arne K.. (1999) Cytokine network in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. American Journal of Cardiology
  Academic article

1998

• Lien, Egil; Aukrust, Pål; Sundan, Andreas; Muller, Fredrik; Frøland, Stig Sophus; Espevik, T. (1998) Elevated levels of serum-soluble CD14 in human immonudeficiency virus type 1 (HIV-1) infection: correlation to disease progression and clinical events. Blood
  Academic article
• Iversen, Ann-Charlotte; Johnsen, Ann-Charlotte; Haux, Johan; Steinkjer, Bjørg; Nonstad, Unni; Egeberg, Kjartan Wøllo. (1998) Regulation of Apo-2 Ligand/TRAIL expression in NK cells - Involvement in NK cell mediated cytotoxicity. Journal of Interferon and Cytokine Research
  Abstract
• Lien, E; Sundan, A; Aukrust, P; Frøland, S; Espevik, Terje. (1998) Elevated levels of serum-soluble CD14 in human immunodeficiency virus type 1 (HIV-1) infection: correlation to disease progression and clinical events. Blood
  Academic article
• Medvedev, AE; Flo, T; Vogel, SN; Robin, R; Golenbock, DT; Teti, G. (1998) Involvement of CD14 and complement receptors CR3 and CR4 in nuclear factor-kappaB activation and TNF production induced by lipopolysaccharide and group B streptococcal cell walls. Journal of Immunology
  Academic article
• Thommesen, Liv; Sjursen, Wenche; Gåsvik, Kathrine; Hanssen, Wenche; Brekke, Ole-Lars; Skattebøl, Lars. (1998) Selective inhibitors of cytosolic or secretory phospholipase A2 block TNF-induced activation of transcription factor nuclear factor-kappa B and expression of ICAM-1. Journal of Immunology
  Academic article
• Halaas, Øyvind; Vik, R; Espevik, Terje. (1998) Induction of Fas ligand in murine bone marrow NK cells by bacterial polysaccharides. Immunology
  Academic article
• Ingalls, RR; Monks, BG; Savedra R, [Mangler fornavn]; Christ, WJ; Delude, RL; Medvedev, AE. (1998) CD11/CD18 and CD14 share a common lipid A signaling pathway. Journal of Immunology
  Academic article
• Kulseng, Bård Eirik; Espevik, Terje; Sundan, A. (1998) Elevated hepatocyte growth factor in sera from patients with insulin-dependent diabetes mellitus. Acta Dermato-Venereologica
  Academic article
• Berntzen, G.; Flo, T; Medvedev, A; Kilaas, L; Skjåk-Bræk, Gudmund; Sundan, A. (1998) The tumor necrosis factor-inducing potency of lipopolysaccharide and uronic acid polymers is increased when they are covalently linked to particles. Clinical and Vaccine Immunology
  Academic article

1997

• Medvedev, Andrei E.; Iversen, Ann-Charlotte; Johnsen, Ann-Charlotte; Haux, Johan; Steinkjer, Bjørg; Egeberg, Kjartan Wøllo. (1997) Regulation of Fas and Fas-Ligand expression in NK cells by cytokines and the involvement of Fas-Ligand in NK/LAK cell-mediated cytotoxicity. Cytokine
  Academic article
• Sandler, Stellan; Andersson, Arne; Eizirik, Décio L.; Hellerström, Claes; Espevik, Terje; Kulseng, Siri. (1997) Assessment of insulin secretion in vitro from microencapsulated fetal procine islet-like cell clusters and rat, mouse, and human pancreatic islets. Transplantation
  Academic article
• Kulseng, Bård Eirik; Thu, Beate; Espevik, Terje; Skjåk-Bræk, Gudmund. (1997) Alginate polylysine microcapsules as immune barrer : permeability of cytokines and immmunoglobulins over the capsule membrane. Cell Transplantation
  Academic article
• Jackson, A.M.; Lien, Egil; Alexandroff, A.B.; Espevik, Terje; James, K.; Selby, P.J.. (1997) Soluble urinary CD14 after intravesical bacille Calmette-Guérin immunotherapy for carcinoma in situ. British Journal of Urology
  Academic article
• Hestdal, Kjetil; Aukrust, Pål; Müller, Fredrik; Lien, Egil; Bjerkeli, Vigdis; Espevik, Terje. (1997) Dysregulation of membrane-bound tumor necrosis factor-_a and tumor necrosis factor receptors on mononuclear cells in human immunodeficiency virus type 1 infection : low percentage of p75-tumor necrosis factor receptor positive cells in patients with advanced disease and high viral load. Blood
  Academic article
• Aukrust, Pål; Hestdal, Ketil; Lien, Egil; Bjerkeli, Vigdis; Nordøy, Ingvild; Espevik, Terje. (1997) Effects of intravenous immunoglobulin in vivo on abnormally increased tumor necrosis factor-alpha activity in human immunodeficiency virus type 1 infection. Journal of Infectious Diseases
  Academic article
• Jahr, Tove Gullstein; Ryan, Liv; Sundan, Anders; Lichenstein, Henri S.; Skjåk-Bræk, Gudmund; Espevik, Terje. (1997) Induction of tumor necrosis factor production from monocytes stimulated with mannuronic acid polymers and involvement of lipopolysaccharide-binding protein, CD14, and bactericidal/ permeability-increasing factor. Infection and Immunity
  Academic article
• Aukrust, Pål; Hestad, Kjetil; Lien, Egil; Bjerkeli, Vigdis; Nordøy, Ingvild; Espevik, T. (1997) Effects of intravenous immunoglobulin in vivo on abnormally increased tumor necrosis factor-_a activity in human immunodeficiency virus type 1 infection. Journal of Infectious Diseases
  Academic article
• Hestad, Kjetil; Aukrust, Pål; Muller, Fredrik; Lien, Egil; Bjerkeli, Vigdis; Espevik, T. (1997) Dysregulation of membrane-bound tumor necrosis factor-_a and tumor necrosis factor receptors on mononuclear cells in human immunodeficiency virus type 1  infection: Low percentage of p75-tumor necrosis factor receptor positive cells in patients with advanced disease and high viral load. Blood
  Academic article

1996

• Aukrust, Pål; Lien, Egil; Kristoffersen, Anne Karin; Muller, Fredrik; Haug, Charlotte J.; Espevik, T. (1996) Persistant Activation of The Tumor Nevcrosis Factor System in a Subgroup of Patients With Common Varable Immunodeficincy - Possible Immunological and Clinical and Consequences. Blood
  Academic article
• Haug, Charlotte J.; Aukrust, Pål; Lien, Egil; Muller, Fredrik; Espevik, T; Frøland, Stig Sophus. (1996) Disseminated Mycobacterium avium complex (MAC) infection in AIDS: Immunopathogenic significance of an activated tumor necrosis factor (TNF) system and depressed serum levels of 1,25-dihydroxyvitamin D. Journal of Infectious Diseases
  Academic article
• Aukrust, Pål; Lien, Egil; Kristoffersen, Anne Karin; Muller, Fredrik; Haug, Charlotte J.; Espevik, T. (1996) Persistent activation of tumor necrosis factor system in a subgroup of patients with common variable immunodeficiency - Possible immunologic and clinical concensus. Blood
  Academic article
• Aukrust, Pål; Lien, Egil; Kristoffersen, Anne K.; Müller, Fredrik; Haug, Charlotte J.; Espevik, Terje. (1996) Persistent activation of the tumor necrosis factor system in a subgroup of patients with common variable immunodeficiency : possible immunologic and clinical consequences. Blood
  Academic article
• Børset, Magne; Lien, Egil; Espevik, Terje; Helseth, Eirik; Waage, Anders; Sundan, Anders. (1996) Concomitant expression of hepatocyte growth factor/scatter factor and the receptor c-MET in human myeloma cell lines. Journal of Biological Chemistry
  Academic article
• Børset, Magne; Medvedev, Andrei E.; Sundan, Anders; Espevik, Terje. (1996) The role of the two TNF receptors in proliferation, NF-_KB activation and discrimination between TNF and LT_a signalling in the human myeloma cell line OH-2. Cytokine
  Academic article
• Haug, Charlotte J.; Aukrust, Pål; Lien, Egil; Müller, Fredrik; Espevik, Terje; Frøland, Stig S.. (1996) Disseminated Mycobacterium avium complex infection in AIDS : immunopathogenic significance of an activated tumor necrosis factor system and depressed serum levels of 1,25 dihydroxyvitamin D. Journal of Infectious Diseases
  Academic article
• Medvedev, Andrei E.; Lægreid, Astrid; Sundan, Anders; Espevik, Terje. (1996) A non-competitive P55 TNF receptor antibody enhances the specific activity of Lymphotoxin-_a. Scandinavian Journal of Immunology
  Academic article
• Medvedev, Andrei E.; Espevik, Terje; Ranges, Gerald; Sundan, Anders. (1996) Distinct roles of the two tumor necrosis factor (TNF) receptors in modulating TNF and lymphotoxin _a effects. Journal of Biological Chemistry
  Academic article
• Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund; Følling, Ivar; Espevik, Terje. (1996) TNF production from peripheral blood mononuclear cells in diabetic patients after stimulation with alginate and lipopolysaccharide. Scandinavian Journal of Immunology
  Academic article
• Thu, Beate; Bruheim, Per; Espevik, Terje; Smidsrød, Olav; Soon-Shiong, P.; Skjåk-Bræk, Gudmund. (1996) Alginate polycation microcapsules. I, Interaction between alginate and polycation. Biomaterials
  Academic article
• Thu, Beate; Bruheim, Per; Espevik, Terje; Smidsrød, Olav; Soon-Shiong, Patrick; Skjåk-Bræk, Gudmund. (1996) Alginate polycation microcapsules. II, Some functional properties. Biomaterials
  Academic article
• Skjåk-Bræk, Gudmund; Espevik, Terje. (1996) Application of alginate gels in biotechnology and biomedicine. Carbohydrates in Europe
  Academic article

1995

• Samuelsen, Anne Berit; Paulsen, Berit Smestad; Wold, Jens Krisitian; Otsuka, Hanako; Yamada, Haruki; Espevik, T. (1995) Isolation and partial characterization of biologically active polysaccharides from Plantago major L. Phytotherapy Research
  Academic article
• Skjåk-Bræk, Gudmund; Espevik, Terje; Otterlei, Marit; Smidsrød, Olav; Soon-Shiong, P.. (1995) Homologous guluronic acid alginate coating composition for in vivo application and implantation and method using the same. US-Patent 5459 054, Oct. 1995
  Report
• Lien, Egil; Liabakk, Nina-Beate; Iversen, Ann-Charlotte; Johnsen, Ann-Charlotte; Nonstad, Unni; Sundan, Anders. (1995) Polymorphonuclear granulocytes enhance lipopolysaccharide-induced p75 tumor necrosis factor receptor release from mononuclear cells. European Journal of Immunology
  Academic article
• Arntzen, KJ; Liabakk, N-B; Jacobsen, G.; Espevik, Terje; Austgulen, Rigmor. (1995) Soluble tumor necrosis factor receptor in serum and urine througout normal pregnancy and delivery. American Journal of Reproductive Immunology
  Academic article
• Skjermo, Jorunn; Defoort, Thomas; Dehasque, Marleen; Espevik, Terje; Olsen, Yngvar; Skjåk-Bræk, Gudmund. (1995) Immunostimulation of juvenile turbot (Scophthalmus maximus L.) using an alginate with high mannuronic acid content administered via the live food organism Artemia. Fish and Shellfish Immunology
  Academic article

1994

• Brekke, OL; Espevik, Terje; Bjerve, Kristian S. (1994) Butylated Hydroxyanisole Inhibits Tumor Necrosis Factor induced Cytotoxicity and Arachidonic Acid Release. Lipids
  Academic article
• Halgunset, J; Johnsen, H; Kjøllesdal, AM; Qvigstad, E; Espevik, Terje; Austgulen, Rigmor. (1994) Normal parturition at term is associated with subtle inflammatory reactions in-utero. European Journal of Obstetrics, Gynecology, and Reproductive Biology
  Academic article
• Waage, A.; Halstensen, Alfred; Espevik, T.; Brandtzæg, P.. (1994) Cytokines in meningococcal disease. Baillière's Clinical Infectious Diseases
  Academic article

1993

• Austgulen, Rigmor; Naume, B; Johnson, A-C; Espevik, Terje; Sundan, A. (1993) Gene expression and secretion of cytokines and cytokines from highly purified CD56* natural killer cells stimulated with interleukin-2, interleukin-7 and interleukin-12. European Journal of Immunology
  Academic article
• Austgulen, Rigmor; Liabakk, N-B; Richardsen, W; Rahimipoor, S; Vatn, I; Espevik, Terje. (1993) Serum levels of soluble TNF receptors are influenced by gestational age and delivery in normal pregnancy. Placenta
  Abstract
• Naume, Bjørn; Iversen, Ann-Charlotte; Johnsen, Ann-Charlotte; Espevik, Terje; Sundan, Anders. (1993) Gene expression and secretion of cytokines and cytokine receptors from hihgly purified CD56+ natural killer cells stimulated with interleukin-2, interleukin-7 and interleukin-12. European Journal of Immunology
  Academic article
• Austgulen, Rigmor; Kjøllesdal, AM; Johnsen, H; Liabakk, N-B; Espevik, Terje. (1993) Soluble receptors for tumor necrosis factor: occurence in association with normal delivery at term. Obstetrics and Gynecology
  Academic article
• Liabakk, N-B; Lien, E; Sundan, A; Sunde, A; Austgulen, Rigmor; Espevik, Terje. (1993) High concentrations of the soluble p55 tumor necrosis factor receptor in human seminal plasma. Human Reproduction
  Academic article
• Austgulen, Rigmor; Liabakk, N-B; Lien, E; Espevik, Terje. (1993) Increased levels of soluble TNF-alpha receptors in serum from pregnant women, and in serum and urine samples from newborns. Pediatric Research
  Academic article
• Waage, A.; Halstensen, Alfred; Espevik, T.; Brandtzæg, P.. (1993) Compartmentalization of the TNF and IL-6 in meningitis and septic shock. Mediators of Inflammation
  Academic article

1992

• Brekke, OL; Shalaby, MR; Sundan, Anders; Espevik, Terje; Bjerve, Kristian S. (1992) Butylated hydroxyanisol specifically inhibits Tumor Necrosis Factor induced cytotoxicity and growth enhancement. Cytokine
  Academic article
• Brekke, OL; Espevik, Terje; Bardal, Tora; Bjerve, Kristian S. (1992) Effects of n-3 and n-6 fatty acids on Tumor Necrosis Factor cytotoxicity in WEHI fibrosarcoma cells. Lipids
  Academic article
• Waage, A.; Halstensen, Alfred; Brandtzæg, P.; Espevik, T.. (1992) TNF in serum in patients with bacterial infections.
  Academic chapter/article/Conference paper
• Austgulen, Rigmor; Espevik, Terje; Mecsei, R; Scott, H. (1992) Expression of receptors for tumor necrosis factor in human placenta at term. Acta Obstetricia et Gynecologica Scandinavica
  Academic article
• Austgulen, Rigmor; Liabakk, N-B; Espevik, Terje. (1992) Sekresjon av løselige reseptorer for tumor nekrose faktor - en immunologisk buffermekanisme under svangerskap?. Tidsskrift for Den norske legeforening
  Academic article
• Austgulen, Rigmor; Liabakk, NB; Brockhaus, M; Espevik, Terje. (1992) Soluble TNF receptors in amniotic fluid and in urine from pregnant women. Journal of Reproductive Immunology
  Academic article
• Soon-Shong, P.; Feldman, E.; Nelson, R.; Komtebedde, J.; Smidsrød, Olav; Skjåk-Bræk, Gudmund. (1992) Successful reversal of spontaneous diabetes in dogs by intraperitonal microencapsulated islets. Transplantation
  Academic article
• Brandtzæg, P.; Halstensen, Alfred; Kierulf, P.; Espevik, T.; Waage, A.. (1992) Molecular mechanisms in the compartmentalized inflammatory response presenting as meningococcal meningitis or septic shock. Microbial Pathogenesis
  Academic article

1991

• Austgulen, Rigmor; Liabakk, N-B; Scott, H; Brockhaus, M; Espevik, Terje. (1991) Soluble TNF receptors in urine and in amniotic fluid from pregnant women. Placenta
  Abstract
• Waage, A.; Brandtzæg, P.; Espevik, T.; Halstensen, Alfred. (1991) Current understanding of the pathogenesis of gram negative shock. Infectious Disease Clinics of North America
  Academic article

1988

• Nissen-Meyer, J; Austgulen, Rigmor; Espevik, Terje. (1988) Synergistic growth inhibitory activity of tumor necrosis factor and interferon-alpha: contribution to the monocyte-derived cytostatic activity towards human leukemia K562 cells. Scandinavian Journal of Immunology
  Academic article
• Nissen-Meyer, J; Hofsli, E; Espevik, Terje; Austgulen, Rigmor. (1988) Involvement of tumor necrosis factor in cytotoxicity mediated by human monocytes. Natural immunity and cell growth regulation
  Academic article

1987

• Bjerve, Kristian S; Espevik, Terje; Kildahl-Andersen, O; Nissen-Meyer, J. (1987) Effect of free fatty acids on the cytolytic activity of tumor necrosis factor/¬monocyte-derived cytotoxic factor. APMIS - Journal of Pathologiy, Microbiology and Immunology
  Academic article
• Austgulen, Rigmor; Espevik, Terje; Nissen-Meyer, J. (1987) Fibroblast growth stimulatory activity from human monocytes: The contribution of tumor necrosis factor. Scandinavian Journal of Immunology
  Academic article
• Austgulen, Rigmor; Espevik, Terje; Degree, M. (1987) Monocyte-derived influence on growth of normal human fibroblasts: The contribution of tumor necrosis factor to growth inhibition. Scandinavian Journal of Immunology
  Academic article
• Nissen-Meyer, J; Austgulen, Rigmor; Espevik, Terje. (1987) Comparison of recombinant tumor necrosis factor and the monocyte-derived cytotoxic factor (CF) which is involved in the monocyte-mediated cytotoxicity. Cancer Research
  Academic article

1986

• Austgulen, Rigmor; Hammerstrøm , J; Espevik, Terje; Nissen-Meyer, J. (1986) Human monocyte cytotoxic factor mediates cytolysis of WEHI 164 cells. Cellular Immunology
  Academic article
• Austgulen, Rigmor; Espevik, Terje; Hammerstrøm, J; Nissen-Meyer, J. (1986) Role of monocyte cytotoxic factor in cytolysis of actinomycin D treated WEHI 164 cells mediated by freshly isolated human adherent mononuclear blood cells. Cancer Research
  Academic article
• Austgulen, Rigmor; Kildahl-Andersen, O; Espevik, Terje. (1986) Monocyte-mediated drug-dependent cellular cytotoxicity: Effects of different WEHI 164 target cell lines. Cancer Immunology and Immunotherapy
  Academic article