Terje Espevik

About

The strategy of my research group is to study the functions of the complement system, inflammasomes and Toll-like receptors in relation to signaling induced by microbes and cholesterol crystals. Our research points to new targets and strategies for treatment of inflammatory diseases. I am the director of Centre of Molecular Inflammation Research (CEMIR) which is a Centre of Excellence (https://www.ntnu.edu/cemir).

Publications

2025

Zhang, Boyao; Orning, Pontus; Lehman, Jesse W.; Dinis, Alexandre; Torres-Ulloa, Leslie; Elling, Roland. (2025) Raver1 links Ripk1 RNA splicing to caspase-8-mediated pyroptotic cell death, inflammation, and pathogen resistance. Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Academic article
Mestvedt, Ingvild Bergdal; Menu, Eline; Misund, Kristine; Slørdahl, Tobias Schmidt; Rasheed, Kashif; Wolowczyk, Camilla Izabel. (2025) Novel SLAMF1-derived peptide induces apoptosis in multiple myeloma cells by targeting IRF4 transcription factor for degradation. bioRxiv
Academic article

2024

Olsen, Maria Belland; Kong, Xiang Yi; Louwe, Maria; Lauritzen, Knut Husø; Schanke, Ylva; Kaasbøll, Ole Jørgen. (2024) SLAMF1-derived peptide exhibits cardio protection after permanent left anterior descending artery ligation in mice. Frontiers in Immunology
Academic article
Fageräng, Beatrice Linnea Christina; Cyranka, Leon; Schjalm, Camilla; Ekholt, Karin; Larsen, Carina Sandem; Heinzelbecker, Julia. (2024) The function of the complement system remains fully intact throughout the course of allogeneic stem cell transplantation. Frontiers in Immunology
Academic article

2023

Nilsen, Kaja Elisabeth; Zhang, Boyao; Skjesol, Astrid; Ryan, Liv; Vagle, Hilde; Bøe, Maren Helene. (2023) Peptide derived from SLAMF1 prevents TLR4-mediated inflammation in vitro and in vivo. Life Science Alliance (LSA)
Academic article
Lentini, Germana; Famà, Agata; De Gaetano, Giuseppe Valerio; Coppolino, Francesco; Mahjoub, Ahlem Khachroub; Ryan, Liv. (2023) Caspase-8 inhibition improves the outcome of bacterial infections in mice by promoting neutrophil activation. Cell Reports Medicine
Academic article
Bjerkhaug, Aline; Granslo, Hildegunn Norbakken; Cavanagh, Jorunn Pauline; Høiland, Ina Isabella; Ludviksen, Judith K; Lau, Corinna. (2023) Dual inhibition of complement C5 and CD14 attenuates inflammation in a cord blood model. Pediatric Research
Academic article

2022

Pinto, Sneha M.; Subbannayya, Yashwanth; Kim, Hera; Hagen, Lars; Górna, Maria W; Nieminen, Anni I.. (2022) Multi-OMICs landscape of SARS-CoV-2-induced host responses in human lung epithelial cells. iScience
Academic article
Nilsen, Kaja Elisabeth; Skjesol, Astrid; Kojen, June Frengen; Espevik, Terje; Stenvik, Jørgen; Yurchenko, Mariya. (2022) TIRAP/Mal Positively Regulates TLR8‐Mediated Signaling via IRF5 in Human Cells. Biomedicines
Academic article
Johnson, Christina; Quach, Huy Quang; Lau, Corinna; Ekholt, Karin; Espevik, Terje; Woodruff, Trent M.. (2022) Thrombin Differentially Modulates the Acute Inflammatory Response to Escherichia coli and Staphylococcus aureus in Human Whole Blood. Journal of Immunology
Academic article

2021

Islam, Rakibul; Islam, Mohammad Mirazul; Nilsson, Per H.; Mohlin, Camilla; Hagen, Kjersti Thorvaldsen; Paschalis, Eleftherios I.. (2021) Combined blockade of complement C5 and TLR co-receptor CD14 synergistically inhibits pig-to-human corneal xenograft induced innate inflammatory responses. Acta Biomaterialia
Academic article
Kim, Hera; Subbannayya, Yashwanth; Humphries, Fiachra; Skjesol, Astrid; Pinto, Sneha M.; Giambelluca, Miriam. (2021) UMP-CMP kinase 2 gene expression in macrophages is dependent on the IRF3-IFNAR signaling axis. PLOS ONE
Academic article
Trifonov, Lena; Yurchenko, Mariya; Skjesol, Astrid; Cohen, Guy; Espevik, Terje; Korshin, Edward E.. (2021) Benzyl-para-di-[5-methyl-4-(n-octylamino) pyrimidin-2(1H)one] as an interferon beta (IFN-β) modulator. Molecular diversity
Academic article
Niyonzima, Nathalie; Rahman, Jubayer; Kunz, Natalie; West, Erin; Freiwald, Tilo; Desai, Jigar V.. (2021) Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation . Science immunology
Academic article

2020

Ehrnstrøm, Birgitta; Kojen, June Frengen; Giambelluca, Miriam; Ryan, Liv; Moen, Siv Helen; Hu, Zhenyi. (2020) TLR8 and complement C5 induce cytokine release and thrombin activation in human whole blood challenged with Gram-positive bacteria. Journal of Leukocyte Biology
Academic article
Niyonzima, Nathalie; Bakke, Siril Skaret; Gregersen, Ida; Holm, Sverre; Sandanger, Øystein; Orrem, Hilde Lang. (2020) Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis. EBioMedicine
Academic article

2019

Skjesol, Astrid; Yurchenko, Mariya; Bösl, Korbinian; Gravastrand, Caroline S.; Nilsen, Kaja Elisabeth; Grøvdal, Lene Melsæther. (2019) The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2. PLoS Pathogens
Academic article
Pilely, Katrine; Bakke, Siril Skaret; Palarasah, Yaseelan; Skjoedt, Mikkel-Ole; Bartels, Emil D.; Espevik, Terje. (2019) Alpha-cyclodextrin inhibits cholesterol crystal-induced complement-mediated inflammation: A potential new compound for treatment of atherosclerosis. Atherosclerosis
Academic article
Lau, Corinna; McAdam, Martin Berner; Bergseth, Grete; Grevys, Algirdas; Bruun, Jack-Ansgar; Ludviksen, Judith K. (2019) NHDL, a recombinant VL/VH hybrid antibody control for IgG2/4 antibodies. mAbs
Academic article
Bösl, Korbinian; Kandasamy, Richard Kumaran; Espevik, Terje. (2019) Novel insights on human–virus interactions through genome–wide approaches. Norwegian University of Science and Technology
Doctoral dissertation
Christensen, Jacob J.; Bakke, Siril Skaret; Ulven, Stine Marie; Retterstøl, Kjetil; Henriksen, Tore; Bollerslev, Jens. (2019) Serum Omega-6 Fatty Acids and Immunology-Related Gene Expression in Peripheral Blood Mononuclear Cells: A Cross-Sectional Analysis in Healthy Children. Molecular Nutrition & Food Research
Academic article
Skjeflo, Espen Waage; Christiansen, Dorte; Landsem, Anne; Stenvik, Jørgen; Woodruff, T. M.; Espevik, Terje. (2019) Phagocytosis of live and dead Escherichia coli and Staphylococcus aureus in human whole blood is markedly reduced by combined inhibition of C5aR1 and CD14. Molecular Immunology
Academic article
Moen, Siv Helen; Ehrnstrøm, Birgitta; Kojen, June Frengen; Yurchenko, Mariya; Beckwith, Kai Sandvold; Afset, Jan Egil. (2019) Human Toll-like receptor 8 (TLR8) is an important sensor of pyogenic bacteria, and is attenuated by cell surface TLR signaling. Frontiers in Immunology
Academic article
Gravastrand, Caroline S.; Steinkjer, Bjørg; Halvorsen, Bente; Landsem, Anne; Skjelland, Mona; Jacobsen, Eva Astrid. (2019) Cholesterol Crystals Induce coagulation Activation through Complement-Dependent Expression of Monocytic Tissue Factor. Journal of Immunology
Academic article
Narverud, Ingunn; Christensen, Jacob J.; Bakke, Siril Skaret; Ulven, Stine Marie; Rundblad, Amanda; Aukrust, Pål. (2019) Profiling of immune-related gene expression in children with familial hypercholesterolaemia. Journal of Internal Medicine
Academic article
Lunde, Ngoc Dieu Nguyen; Gregersen, Ida; Ueland, Thor; Shetelig, Christian; Holm, Sverre; Kong, Xiang Yi. (2019) Legumain is upregulated in acute cardiovascular events and associated with improved outcome – potentially related to anti-inflammatory effects on macrophages. Atherosclerosis
Academic article
Thomas, Anub Mathew; Gerogianni, Alexandra; McAdam, Martin Berner; Fløisand, Yngvar; Lau, Corinna; Espevik, Terje. (2019) Complement component C5 and TLR molecule CD14 mediate heme-induced thromboinflammation in human blood. Journal of Immunology
Academic article

2018

Skjeflo, Espen Waage; Christiansen, Dorte; Fure, Hilde; Ludviksen, Judith K; Woodruff, Trent M.; Espevik, Terje. (2018) Staphylococcus aureus-induced complement activation promotes tissue factor-mediated coagulation. Journal of Thrombosis and Haemostasis
Academic article
Kleveland, Ola; Ueland, Thor; Kunszt, Gabor; Bratlie, Marte; Yndestad, Arne; Broch, Kaspar. (2018) Interleukin-6 receptor inhibition with tocilizumab induces a selective and substantial increase in plasma IP-10 and MIP-1β in non-ST-elevation myocardial infarction. International Journal of Cardiology
Academic article
Thomas, Anub Mathew; Schjalm, Camilla; Nilsson, Per; Lindenskov, Paal Helge H.; Rørtveit, Runa; Solberg, Rønnaug. (2018) Combined Inhibition of C5 and CD14 Attenuates Systemic Inflammation in a Piglet Model of Meconium Aspiration Syndrome. Neonatology
Academic article
Landsem, Anne; Fure, Hilde; Ludviksen, Judith K; Christiansen, Dorte; Lau, Corinna; Mathisen, Monica Dammen. (2018) Complement component 5 does not interfere with physiological hemostasis but is essential for Escherichia coli-induced coagulation accompanied by Toll-like receptor 4. Clinical and Experimental Immunology
Academic article
Nejati Moharrami, Neda; Boyartchuk, Victor; Espevik, Terje. (2018) Role of CD5L in control of human innate immune function. Doktoravhandlinger ved NTNU (395)
Doctoral dissertation
Orrem, Hilde Lang; Nilsson, Per; Pischke, Søren Erik; Kleveland, Ola; Yndestad, Arne; Ekholt, Karin. (2018) IL-6 receptor inhibition by tocilizumab attenuated expression of C5a receptor 1 and 2 in non-ST-elevation myocardial infarction. Frontiers in Immunology
Academic article
Yurchenko, Mariya; Skjesol, Astrid; Ryan, Liv; Richard, Gabriel Mary; Kandasamy, Richard Kumaran; Wang, Ninghai. (2018) SLA MF1 is required for TLR4-mediated TRAM-TRIF- dependent signaling in human macrophages. Journal of Cell Biology
Academic article
Christ, Anette; Günther, Patrick; Lauterbach, Mario A.R.; Duewell, Peter; Biswas, Debjani; Pelka, Karin. (2018) Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming. Cell
Academic article
Nejati Moharrami, Neda; Tande, Erlend Bjørkøy; Ryan, Liv; Espevik, Terje; Boyartchuk, Victor. (2018) RORα controls inflammatory state of human macrophages. PLOS ONE
Academic article
Bösl, Korbinian; Giambelluca, Miriam; Haug, Markus; Bugge, Marit; Espevik, Terje; Kandasamy, Richard Kumaran. (2018) Coactivation of TLR2 and TLR8 in primary human monocytes triggers a distinct inflammatory signaling response. Frontiers in Physiology
Academic article

2017

Stavik, Benedicte; Holm, Sverre; Espada Serrano, Sandra; Iversen, Nina; Sporsheim, Bjørnar; Bjerkeli, Vigdis. (2017) Increased expression of TFPI in human carotid stenosis. Thrombosis Research
Academic article
Espevik, Terje. (2017) Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation. Journal of Immunology
Academic article
Bakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Pilely, Katrine; Ryan, Liv; Skjelland, Mona. (2017) Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation. Journal of Immunology
Academic article
Ehrnstrøm, Birgitta; Beckwith, Kai Sandvold; Yurchenko, Mariya; Moen, Siv Helen; Kojen, June Frengen; Lentini, Germana. (2017) Toll-Like Receptor 8 Is a Major Sensor of Group B Streptococcus But Not Escherichia coli in Human Primary Monocytes and Macrophages. Frontiers in Immunology
Academic article
Lunde, Ngoc Nguyen Dieu; Holm, Sverre; Dahl, Tuva Børresdatter; Inass, Elyouncha; Sporsheim, Bjørnar; Gregersen, Ida. (2017) Increased levels of legumain in plasma and plaques from patients with carotid atherosclerosis. Atherosclerosis
Academic article
Bugge, Marit; Bergstrøm, Bjarte; Eide, Oda K.; Solli, Helene; Kjønstad, Ingrid Fadum; Stenvik, Jørgen. (2017) Surface Toll-Like Receptor 3 Expression in Metastatic Intestinal Epithelial Cells induces Selective Cytokine Production and Promotes Invasiveness. Journal of Biological Chemistry
Academic article
Espada Serrano, Sandra; Stavik, Benedicte; Holm, Sverre; Sagen, Ellen Lund; Bjerkeli, Vigdis; Skjelland, Mona. (2017) Tissue factor pathway inhibitor attenuates ER stress-induced inflammation in human M2-polarized macrophages. Biochemical and Biophysical Research Communications - BBRC
Academic article
Barratt-Due, Andreas; Pischke, Søren Erik; Nilsson, Per; Espevik, Terje; Mollnes, Tom Eirik. (2017) Dual inhibition of complement and Toll-like receptors as a novel approach to treat inflammatory diseases-C3 or C5 emerge together with CD14 as promising targets. Journal of Leukocyte Biology
Academic literature review
Niyonzima, Nathalie; Halvorsen, Bente; Sporsheim, Bjørnar; Garred, Peter; Aukrust, Pål; Mollnes, Tom Eirik. (2017) Complement activation by cholesterol crystals triggers a subsequent cytokine response. Molecular Immunology
Academic article
Gregersen, Ida; Sandanger, Øystein; Askevold, Erik Tandberg; Sagen, Ellen Lund; Yang, Kuan; Holm, Sverre. (2017) Interleukin 27 is increased in carotid atherosclerosis and promotes NLRP3 inflammasome activation. PLOS ONE
Academic article
Gravastrand, Caroline; Hamad, Shamal; Fure, Hilde; Steinkjer, Bjørg; Ryan, Liv; Oberholzer, José. (2017) Alginate microbeads are coagulation compatible, while alginate microcapsules activate coagulation secondary to complement or directly through FXII. Acta Biomaterialia
Academic article
Stavik, Benedicte; Espada, Sandra; Holm, Sverre; Bjerkeli, Vigdis; Sandset, Per Morten; Dahl, Tuva Børresdatter. (2017) TFPI in human atherosclerotic plaques. Research and Practice in Thrombosis and Haemostasis (RPTH)
Abstract
Hellerud, Bernt C; Orrem, Hilde Lang; Dybwik, Knut Gustav; Pischke, Søren Erik; Barratt-Due, Andreas; Castellheim, Albert. (2017) Combined inhibition of C5 and CD14 efficiently attenuated the inflammatory response in a porcine model of meningococcal sepsis. Journal of Intensive Care
Academic article

2016

Varghese, Paramel G; Folkersen, Lasse; Strawbridge, Rona J.; Halvorsen, Bente; Yndestad, Arne; Ranheim, Trine. (2016) NLRP3 inflammasome expression and activation in human atherosclerosis. Journal of the American Heart Association (JAHA)
Academic article
Gustavsen, Alice; Nymo, Stig Haugset; Landsem, Anne; Christiansen, Dorte; Ryan, Liv; Husebye, Harald. (2016) Combined inhibition of complement and CD14 attenuates bacteria-induced inflammation in human whole blood more efficiently than antagonizing the toll-like receptor 4-MD2 complex. Journal of Infectious Diseases
Academic article
Ørning, Mathias Pontus; Hoem, Kine Samset; Coron, Abba Elizabeth; Skjåk-Bræk, Gudmund; Mollnes, Tom Eirik; Brekke, Ole Lars. (2016) Alginate microsphere compositions dictate different mechanisms of complement activation with consequences for cytokine release and leukocyte activation. Journal of Controlled Release
Academic article
Sherstova, Tatyana; Stokke, Bjørn Torger; Anthonsen, Marit Walbye; Espevik, Terje. (2016) Quantitative atomic force microscopy and light microscopy of hydrogels and cells. Norwegian University of Science and Technology
Doctoral dissertation
Bugge, Marit; Nilsen, Nadra J.; Espevik, Terje. (2016) Toll-Like Receptor 3 Signaling in Intestinal Epithelial Cells. Norwegian University of Science and Technology
Doctoral dissertation
Kleveland, Ola; Kunszt, Gabor; Bratlie, Marte; Ueland, Thor; Broch, Kaspar; Holte, Espen. (2016) Effect of a single dose of the interleukin-6 receptor antagonist tocilizumab on inflammation and troponin T release in patients with non-ST-elevation myocardial infarction: a double-blind, randomized, placebo-controlled phase 2 trial. European Heart Journal
Academic article
Niyonzima, Nathalie; Freeley, Simon; Arbore, Giuseppina; Le Friec, Gaelle; Lappegård, Knut Tore; Mollnes, Tom Eirik. (2016) The intracellular C5 system is critical to DAMP sensing and cellular responses in human monocytes. Immunobiology
Abstract
Zimmer, Sebastian; Grebe, Alena; Bakke, Siril Skaret; Bode, Niklas; Halvorsen, Bente; Ulas, Thomas. (2016) Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming. Science Translational Medicine
Academic article
Nymo, Stig Haugset; Gustavsen, Alice; Nilsson, Per; Lau, Corinna; Espevik, Terje; Mollnes, Tom Eirik. (2016) Human endothelial cell activation by Escherichia coli and staphylococcus aureus is mediated by TNF and IL-1β secondarily to activation of C5 and CD14 in whole blood. Journal of Immunology
Academic article
Pilely, Katrine; Rosbjerg, Anne; Genster, Ninette; Gál, Peter; Pál, Gábor; Halvorsen, Bente. (2016) Cholesterol crystals activate the lectin complement pathway via ficolin-2 and mannose-binding lectin: Implications for the progression of atherosclerosis. Journal of Immunology
Academic article
Malmo, Jostein; Moe, Nina; Krokstad, Sidsel; Ryan, Liv; Loevenich, Simon; Johnsen, Ingvild Bjellmo. (2016) Cytokine profiles in human metapneumovirus infected children: Identification of genes involved in the antiviral response and pathogenesis. PLOS ONE
Academic article

2015

Espevik, Terje. (2015) Reconstituted High-Density Lipoprotein Attenuates Cholesterol Crystal-Induced Inflammatory Responses by Reducing Complement Activation. Journal of Immunology
Academic article
Hovland, Anders; Jonasson, Lena; Garred, Peter; Yndestad, Arne; Aukrust, Pål; Lappegård, Knut Tore. (2015) The complement system and toll-like receptors as integrated players in the pathophysiology of atherosclerosis. Atherosclerosis
Academic literature review
Egge, Kjetil Hagene; Barratt-Due, Andreas; Nymo, Stig Haugset; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Lau, Corinna. (2015) The anti-inflammatory effect of combined complement and CD14 inhibition is preserved during escalating bacterial load. Clinical and Experimental Immunology
Academic article
Nilsen, Nadra; Gregory I., Vladimer; Stenvik, Jørgen; Ørning, Mathias Pontus; Zeid-Kilani, Maria Vanessa; Bugge, Marit. (2015) A role for the adaptor proteins TRAM and TRIF in toll-like receptor 2 signaling. Journal of Biological Chemistry
Academic article
Lau, Corinna; Olstad, Ole Kristoffer; Holden, Marit; Nygård, Ståle; Fure, Hilde; Lappegård, Knut Tore. (2015) Gene expression profiling of Gram-negative bacteria-induced inflammation in human whole blood: The role of complement and CD14-mediated innate immune response. Genomics Data
Academic article
Sponaas, Anne-Marit; Moen, Siv Helen; Liabakk, Nina-Beate; Feyzi, Emadoldin; Holien, Toril; Kvam, Solveig. (2015) The proportion of CD16+CD14dim monocytes increases with tumor cell load in bone marrow of patients with multiple myeloma. Immunity,Inflammation and Disease
Academic article
Skjeflo, Espen Waage; Sagatun, Caroline; Dybwik, Knut; Aam, Sturla; Urving, Sven Haakon; Nunn, Miles A.. (2015) Combined inhibition of complement and CD14 improved outcome in porcine polymicrobial sepsis. Critical Care
Academic article
Bergstrøm, Bjarte; Aune, Marie Hjelmseth; Awuh, Jane Atesoh; Kojen, June Frengen; Blix, Kjetil Jordahl; Ryan, Liv. (2015) TLR8 senses Staphylococcus aureus RNA in human primary monocytes and macrophages and induces IFN-β production via a TAK1-IKKβ-IRF5 signaling pathway. Journal of Immunology
Academic article
Niyonzima, Nathalie; Samstad, Eivind; Aune, Marie Hjelmseth; Ryan, Liv; Bakke, Siril Skaret; Rokstad, Anne Mari. (2015) Reconstituted high-density lipoprotein attenuates cholesterol crystal-induced inflammatory responses by reducing complement activation. Journal of Immunology
Academic article
Klein, Dionne; Skjesol, Astrid; Kers-Rebel, Esther D.; Sherstova, Tatyana; Sporsheim, Bjørnar; Egeberg, Kjartan Wøllo. (2015) CD14, TLR4 and TRAM Show Different Trafficking Dynamics During LPS Stimulation. Traffic: The moving front of cell biology
Academic article
Lau, Corinna; Nygård, Ståle; Fure, Hilde; Olstad, Ole Kristoffer; Holden, Marit; Lappegård, Knut Tore. (2015) CD14 and complement crosstalk and largely mediate the transcriptional response to Escherichia coli in human whole blood as revealed by DNA microarray. PLOS ONE
Academic article

2014

Lappegård, Knut Tore; Garred, Peter; Jonasson, Lena; Espevik, Terje; Aukrust, Pål; Yndestad, Arne. (2014) A vital role for complement in heart disease. Molecular Immunology
Academic literature review
Samstad, Eivind; Niyonzima, Nathalie; Nymo, Stig Haugset; Aune, Marie Hjelmseth; Ryan, Liv; Bakke, Siril Skaret. (2014) Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release. Journal of Immunology
Academic article
Østvik, Ann Elisabet; Granlund, Atle Van Beelen; Gustafsson, Björn; Torp, Sverre Helge; Espevik, Terje; Mollnes, Tom Eirik. (2014) Mucosal toll-like receptor 3-dependent synthesis of complement factor B and systemic complement activation in inflammatory bowel disease. Inflammatory Bowel Diseases
Academic article
Franklin, Bernardo S; Bossaller, Lukas; De Nardo, Dominic; Ratter, Jacqueline M; Stutz, Andrea; Engels, Gudrun. (2014) The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation. Nature Immunology
Academic article
Huber-Lang, Markus; Barratt-Due, Andreas; Pischke, Søren Erik; Sandanger, Øystein; Nilsson, Per; Nunn, Miles A.. (2014) Double blockade of CD14 and complement C5 abolishes the cytokine storm and improves morbidity and survival in polymicrobial sepsis in mice. Journal of Immunology
Academic article
Nymo, Stig Haugset; Niyonzima, Nathalie; Espevik, Terje; Mollnes, Tom Eirik. (2014) Cholesterol crystal-induced endothelial cell activation is complement-dependent and mediated by TNF. Immunobiology
Academic article
Skjeflo, Espen Waage; Christiansen, Dorte; Espevik, Terje; Nielsen, Erik Waage; Mollnes, Tom Eirik. (2014) Combined inhibition of complement and CD14 efficiently attenuated the inflammatory response induced by staphylococcus aureus in a human whole blood model. Journal of Immunology
Academic article
Nordgård, Catherine Taylor; Nonstad, Unni; Olderøy, Magnus Østgård; Espevik, Terje; Draget, Kurt Ingar. (2014) Alterations in mucus barrier function and matrix structure induced by guluronate oligomers. Biomacromolecules
Academic article
Arlov, Øystein; Aachmann, Finn Lillelund; Sundan, Anders; Espevik, Terje; Skjåk-Bræk, Gudmund. (2014) Heparin-Like Properties of Sulfated Alginates with Defined Sequences and Sulfation Degrees. Biomacromolecules
Academic article

2013

Hetland, Geir; Tryggestad, Anne Merete Aaland; Espevik, Terje; Ryan, Liv. (2013) The medicinal mushroom Agaricus blazei Murill promotes NF-B activation via stimulation of TLR2 and inhibits its activation via TLR4. Journal of Pharmaceutical and Biomedical Sciences
Academic article
Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Strand, Berit Løkensgard. (2013) The induction of cytokines by polycation containing microspheres by a complement dependent mechanism. Biomaterials
Academic article
Østvik, Ann Elisabet; Granlund, Atle; Bugge, Marit; Nilsen, Nadra; Torp, Sverre Helge; Waldum, Helge. (2013) Enhanced expression of CXCL10 in inflammatory bowel disease: Potential role of mucosal toll-like 3 receptor stimulation. Inflammatory Bowel Diseases
Academic article
Lau, Corinna; Gunnarsen, Kristin Støen; Høydahl, Lene Støkken; Andersen, Jan Terje; Berntzen, Gøril; Pharo, Anne Margrethe. (2013) Chimeric Anti-CD14 IGG2/4 Hybrid Antibodies for Therapeutic Intervention in Pig and Human Models of Inflammation. Journal of Immunology
Academic article
Nymo, Stig Haugset; Samstad, Eivind; Niyonzima, Nathalie; Aune, Marie Hjelmseth; Bergseth, Grete; Ryan, Liv. (2013) Cholesterol crystals activate the complement system and are phagocytosed in a complement-dependent manner. Molecular Immunology
Abstract
Samstad, Eivind; Niyonzima, Nathalie; Nymo, Stig Haugset; Aune, Marie Hjelmseth; Ryan, Liv; Brekke, Ole Lars. (2013) Cholesterol crystals induce inflammasome activation and cytolcine release in a complement-dependent manner. Molecular Immunology
Abstract
Sandanger, Øystein; Ranheim, Trine; Vinge, Leif Erik; Bliksøen, Marte; Alfsnes, Katrine; Finsen, Alexandra. (2013) The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury. Cardiovascular Research (CVR)
Academic article
Grimstad, Øystein; Husebye, Harald; Espevik, Terje. (2013) TLR3 mediates release of IL-1 beta and cell death in keratinocytes in a caspase-4 dependent manner. Journal of dermatological science (Amsterdam)
Academic article
Østvik, Ann Elisabet; Granlund, Atle Van Beelen; Torp, Sverre Helge; Flatberg, Arnar; Beisvag, Vidar; Waldum, Helge. (2013) Expression of Toll-like receptor-3 is enhanced in active inflammatory bowel disease and mediates the excessive release of lipocalin 2. Clinical and Experimental Immunology
Academic article
Granlund, Atle Van Beelen; Flatberg, Arnar; Østvik, Ann Elisabet; Drozdov, Ignat; Gustafsson, Björn; Kidd, Mark. (2013) Whole Genome Gene Expression Meta-Analysis of Inflammatory Bowel Disease Colon Mucosa Demonstrates Lack of Major Differences between Crohn's Disease and Ulcerative Colitis. PLOS ONE
Academic article
Espevik, Terje. (2013) CEMIR sitt forskningstema er inflammasjon.
Website (informational material)
Espevik, Terje. (2013) CEMIR's research topic is inflammation.
Website (informational material)
Espevik, Terje. (2013) Sensorer som setter i gang betennelse: hvordan virker de og hvorfor trenger vi dem?. Årbok / Det norske videnskaps-akademi
Popular scientific article
Mollnes, Tom Eirik; Barratt-Due, Andreas; Pischke, Søren Erik; Sandanger, Inger; Nilsson, Per; Lambris, J. (2013) Double-blockade of CD14 and complement component C5 abolish the inflammatory storm and improve survival in mouse polymicrobial sepsis. Molecular Immunology
Abstract
Rokstad, Anne Mari; Strand, Berit Løkensgard; Espevik, Terje; Mollnes, Tom Eirik. (2013) Biocompatibility and Biotolerability Assessment of Microspheres Using a Whole Blood Model. Micro and Nanosystems
Academic article

2012

Grimstad, Øystein; Pukstad, Brita; Stenvik, Jørgen; Espevik, Terje. (2012) Oligodeoxynucleotides inhibit Toll-like receptor 3 mediated cytotoxicity and CXCL8 release in keratinocytes. Experimental Dermatology
Academic article
Doyle, SL; Husebye, Harald; Connolly, D; Espevik, Terje; O'Neill, LAJ; McGettrick, AF. (2012) The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation. Nature Communications
Academic article
Rokstad, Anne Mari; Gustafsson, Björn; Espevik, Terje; Bakke, Ingunn; Pfragner, Roswitha; Svejda, Bernhard. (2012) Microencapsulation of small intestinal neuroendocrine neoplasm cells for tumor model studies. Cancer Science
Academic article
Stenvik, Jørgen; Sletta, Håvard; Grimstad, Øystein; Pukstad, Brita; Ryan, Liv; Aune, Randi. (2012) Alginates induce differentiation and expression of CXCR7 and CXCL12/SDF-1 in human keratinocytes - the role of calcium. Journal of Biomedical Materials Research. Part A
Academic article
Klein, Dionne; Øvrebø, Kirsti Marie; Latz, Eicke; Espevik, Terje; Stokke, Bjørn Torger. (2012) Direct measurement of the interaction force between immunostimulatory CpG-DNA and TLR9 fusion protein. Journal of Molecular Recognition
Academic article
Granlund, Atle; Flatberg, Arnar; Østvik, Ann Elisabet; Drozdov, I; Gustafsson, Björn; Kidd, M. (2012) Dissecting the IBD Transcriptome. Inflammatory Bowel Diseases
Abstract
Barratt-Due, Andreas; Pischke, Søren Erik; Brekke, Ole Lars; Thorgersen, Ebbe Billmann; Nielsen, Erik Waage; Espevik, Terje. (2012) Bride and groom in systemic inflammation - The bells ring for complement and Toll in cooperation. Immunobiology
Academic literature review
Østvik, Ann Elisabet; Nilsen, Nadra; Granlund, Atle; Torp, Sverre Helge; Flatberg, Arnar; Waldum, Helge. (2012) Enhanced expression of CXCL10 in inflammatory bowel disease-role of mucosal TLR3 stimulation. Journal of Crohn’s and Coltis Supplements
Abstract
Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Lambris, John D.. (2012) Poly-cation containing alginate microcapsules induce cytokines by a complement-dependent mechanism. Immunobiology
Abstract
Østvik, Ann Elisabet; Granlund, Atle Van Beelen; Torp, Sverre Helge; Flatberg, Arnar; Waldum, Helge; Espevik, Terje. (2012) Induction of Lipocalin-2 in Colonic Epithelial Cells in Inflammatory Bowel Disease. Inflammatory Bowel Diseases
Abstract
Christiansen, Dorte; Brekke, Ole Lars; Stenvik, Jørgen; Lambris, J.D.; Espevik, Terje; Mollnes, Tom Eirik. (2012) Differential Effect of Inhibiting MD-2 and CD14 on LPS- Versus Whole E. coli Bacteria-Induced Cytokine Responses in Human Blood. Advances in Experimental Medicine and Biology
Academic article
Nymo, Stig; Samstad, Eivind; Niyonzima, Nathalie; Bergseth, Grethe; Christiansen, Dorte; Ryan, Liv. (2012) Complement dependency of cholesterol crystal-induced inflammation - I. Pathway activation mechanisms, cytokine responses and endothelial cell activation. Immunobiology
Abstract
Christiansen, Dorte; Stenvik, Jørgen; Brekke, Ole Lars; Lambris, John D.; Espevik, Terje; Mollnes, Tom Eirik. (2012) Phagocytosis of Escherichia coli in human whole blood: Early complement dependency is succeeded by late CD14 dependency over time. Immunobiology
Abstract
Mollnes, Tom Eirik; Barratt-Due, Andreas; Pischke, Søren Erik; Sandanger, Øystein; Nunn, Miles A.; Espevik, Terje. (2012) The systemic inflammatory reaction in polymicrobial sepsis induced by murine cecal ligation and puncture is equally dependent on C5 and CD14. Immunobiology
Abstract
Niyonzima, Nathalie; Samstad, Eivind; Aune, Marie Hjelmseth; Ryan, Liv; Damås, Jan Kristian; Wright, Samuel. (2012) Complement dependency of cholesterol crystal-induced inflammation - II. Inflammasome activation and regulation mechanisms involving reconstituted high density lipoprotein (HDL) and C-reactive protein (CRP). Immunobiology
Abstract
Lau, Corinna; Gunnarsen, Kristin Støen; Høydahl, Lene Støkken; Berntzen, Gøril; Stokes, Christopher R.; Espevik, Terje. (2012) Recombinant anti-human and anti-porcine CD14 antibodies. Immunobiology
Abstract
Skjeflo, Espen; Christiansen, Dorte; Lambris, John D.; Espevik, Terje; Nielsen, Erik Waage; Mollnes, Tom Eirik. (2012) Combined inhibition of complement and CD14 efficiently attenuated the inflammatory response induced by Staphylococcus aureus in a human whole blood model. Immunobiology
Abstract

2011

Torgersen, Maria Lyngaas; Engedal, Kim Nikolai; Pedersen, Anne-Mari Gjestvang; Husebye, Harald; Espevik, Terje; Sandvig, Kirsten. (2011) Toll-like receptor 4 facilitates binding of Shiga toxin to colon carcinoma and primary umbilical vein endothelial cells. FEMS Immunology and Medical Microbiology
Academic article
Grimstad, Øystein; Sandanger, Øystein; Ryan, Liv; Otterdal, Kari; Damås, Jan Kristian; Pukstad, Brita. (2011) Cellular sources and inducers of cytokines present in acute wound fluid. Wound Repair and Regeneration
Academic article
Nørgaard, Nikolai Nordberg; Holien, Toril; Jönsson, S; Hella, Hanne; Espevik, Terje; Sundan, Anders. (2011) CpG-ODN inhibits Smad-dependent BMP signaling; Effects on myeloma cell apoptosis and in vitro osteoblastogenesis. Bone
Abstract
Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Strand, Berit Løkensgard. (2011) Alginate microbeads are complement compatible, in contrast to polycation containing microcapsules, as revealed in a human whole blood model. Acta Biomaterialia
Academic article

2010

Husebye, Harald; Aune, Marie Hjelmseth; Stenvik, Jørgen; Samstad, Eivind Ottersen; Skjeldal, Frode Miltzow; Halaas, Øyvind. (2010) The Rab11a GTPase Controls Toll-like Receptor 4-Induced Activation of Interferon Regulatory Factor-3 on Phagosomes. Immunity
Academic article
Salvesen, Bodil; Stenvik, Jørgen; Rosetti, Carlo; Saugstad, Ola D; Espevik, Terje; Mollnes, Tom E.. (2010) Meconium-induced release of cytokines is mediated by the TRL4/MD-2 complex in a CD14-dependent manner. Molecular Immunology
Academic article
Etokebe, GE; Skjeldal, F; Nilsen, Nadra; Rodionov, Dmitrii; Knezevic, Jelena; Bulat-Kardum, Ljiljana. (2010) Toll-Like Receptor 2 (P631H) Mutant Impairs Membrane Internalization and is a Dominant Negative Allele. Scandinavian Journal of Immunology
Academic article
Duewell, P; Kono, H; Rayner, KJ; Sirois, CM; Vladimer, G; Bauernfeind, FG. (2010) NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature
Academic article
Halaas, Øyvind; Steigedal, Magnus; Haug, Markus; Awuh, Jane Atesoh; Ryan, Liv; Brech, Andreas. (2010) Intracellular Mycobacterium avium Intersect Transferrin in the Rab11(+) Recycling Endocytic Pathway and Avoid Lipocalin 2 Trafficking to the Lysosomal Pathway. Journal of Infectious Diseases
Academic article
Nilsen, Asbjørn Magne; Vik, Randi; Behrens, Carl; Drabløs, Per Arne; Espevik, Terje. (2010) Beryllium Sensitivity Among Workers at a Norwegian Aluminum Smelter. American Journal of Industrial Medicine
Academic article
Nørgaard, Nikolai Nordberg; Holien, Toril; Jonsson, Sofia; Hella, Hanne; Espevik, Terje; Sundan, Anders. (2010) CpG-Oligodeoxynucleotide Inhibits Smad-Dependent Bone Morphogenetic Protein Signaling: Effects on Myeloma Cell Apoptosis and In Vitro Osteoblastogenesis. Journal of Immunology
Academic article
Klein, Dionne C.G.; Latz, Eicke; Espevik, Terje; Stokke, Bjørn Torger. (2010) Higher order structure of short immunostimulatory oligonucleotides studied by atomic force microscopy. Ultramicroscopy
Academic article
Pukstad, Brita; Ryan, Liv; Flo, Trude Helen; Stenvik, Jørgen; Moseley, Ryan; Harding, Keith. (2010) Non-healing is associated with persistent stimulation of the innate immune response in chronic venous leg ulcers. Journal of dermatological science (Amsterdam)
Academic article
Christiansen, D; Brekke, Ole Lars; Stenvik, Jørgen; Lambris, JD; Espevik, Terje; Mollnes, Tom Eirik. (2010) Differential effect of inhibiting MD-2 and CD14 on LPS- versus whole E. coli bacteria-induced cytokine responses in human blood. Molecular Immunology
Abstract
Hetland, Geir; Tryggestad, Anne Merete Aaland; Espevik, Terje; Ryan, Liv; Tangen, Jon-Magnus; Johnson, Egil. (2010) The Medicinal and Antitumor Mushroom, Agaricus Blazei Murill, Activates NF-kappa B Via TLR2 but Not TLR4 In Monocytic Cells, and Stimulates Monocyte-Derived Dendritic Cells (MDDC) to Increased Cell Surface Marker Expression and Cytokine Production, and May Thus Have Adjuvant Effect In MDDC Cancer Vaccines. Blood
Abstract
Hetland, Geir; Tryggestad, Anne Merete Aaland; Espevik, Terje; Ryan, Liv; Tangen, Jon-Magnus; Johnson, Egil. (2010) The medicinal and antitumour mushroom, agaricus blazei murill, activates NF-KB via TLR2 in monocytic cells and induces expression of cell surface markers and production of cytokines in human monocyte-derived dendritic cells (MDDC) in vitro. European Journal of Cancer
Abstract
Grimstad, Øystein; Pukstad, Brita; Stenvik, Jørgen; Espevik, Terje. (2010) TLR3 mediated cytotoxicity in keratinocytes is inhibited by co-stimulation with oligodeoxynucleotides. Journal of Investigative Dermatology
Abstract

2009

Castellheim, A; Brekke, Ole Lars; Espevik, T; Harboe, M; Harboe, M; Mollnes, Tom Eirik. (2009) Innate Immune Responses to Danger Signals in Systemic Inflammatory Response Syndrome and Sepsis. Scandinavian Journal of Immunology
Academic literature review
Standal, Therese; Norgaard, NN; Bohnhorst, J; Espevik, T; Waage, A; Sundan, A. (2009) Does Toll-like Receptor 9 Signaling Play a Role in Myeloma Disease Progression?. Clinical Lymphoma & Myeloma
Abstract
Damås, Jan Kristian; Davi, Giovanni; Jensenius, M; Santilli, F; Otterdal, K; Ueland, T. (2009) Relative chemokine and adhesion molecule expression in Mediterranean spotted fever and African tick bite fever. Journal of Infection
Academic article
Yndestad, A; Landrø, Linn; Ueland, Thor; Dahl, CP; Flo, Trude Helen; Vinge, Leif Erik. (2009) Increased systemic and myocardial expression of neutrophil gelatinase-associated lipocalin in clinical and experimental heart failure. European Heart Journal
Academic article
Espevik, Terje; Rokstad, Anne Mari; Kulseng, Bård Eirik; Strand, Berit Løkensgard; Skjåk-Bræk, Gudmund. (2009) Mechanisms of the host immune response to alginate microcapsules.
Chapter
Iversen, Ann-Charlotte; Steinkjer, Bjørg; Nilsen, Nadra; Bohnhorst, Janne Øvrebø; Moen, Siv Helen; Vik, Randi. (2009) A proviral role for CpG in cytomegalovirus infection. Journal of Immunology
Academic article
Palsson-McDermott, EM; Doyle, SL; McGettrick, AF; Hardy, M; Husebye, Harald; Banahan, K. (2009) TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway. Nature Immunology
Academic article
Sandanger, Øystein; Sandanger, O; Ryan, Liv; Bohnhorst, Janne Øvrebø; Iversen, Ann-Charlotte; Iversen, AC. (2009) IL-10 Enhances MD-2 and CD14 Expression in Monocytes and the Proteins Are Increased and Correlated in HIV-Infected Patients. Journal of Immunology
Academic article

2008

Hetland, G; Tryggestad, AMA; Forland, T; Johnson, E; Ryan, L; Espevik, Terje. (2008) Proposed immunomodulatory co-therapy for hematological cancer by the medicinal mushroom Agaricus blazei Murill, is facilitated by its stimulation of TLR2 and activation of NF-KB. Vox Sanguinis
Abstract
Nilsen, Nadra; Deininger, S; Nonstad, Unni; Skjeldal, F; Husebye, Harald; Rodionov, D. (2008) Cellular trafficking of lipoteichoic acid and Toll-like receptor 2 in relation to signaling; role of CD14 and CD36. Journal of Leukocyte Biology
Academic article
Mollnes, Tom Eirik; Christiansen, D; Brekke, Ole Lars; Espevik, T. (2008) Hypothesis: Combined inhibition of complement and CD14 as treatment regimen to attenuate the inflammatory response. Advances in Experimental Medicine and Biology
Academic article
Hellerud, BC; Stenvik, Jørgen; Espevik, Terje; Lambris, John D.; Mollnes, Tom Eirik; Brandtzaeg, P. (2008) Stages of meningococcal sepsis stimulated in vitro, with emphasis on complement and Toll-like receptor activation. Infection and Immunity
Academic article
Hellerud, BC; Stenvik, Jørgen; Espevik, Terje; Lambris, JD; Mollnes, TE; Brandtzæg, Petter. (2008) Stages of meningococcal sepsis simulated in vitro, with emphasis on complement and Toll-like receptor activation. Infection and Immunity
Academic article
Landrø, Linn Aina Ysland; Landro, L; Damås, Jan Kristian; Damas, JK; Flo, Trude Helen; Heggelund, L. (2008) Decreased serum lipocalin-2 levels in human immunodeficiency virus-infected patients: increase during highly active anti-retroviral therapy. Clinical and Experimental Immunology
Academic article
Klein, Dionne C.G.; Latz, Eicke; Espevik, Terje; Stokke, Bjørn Torger. (2008) Effects of CpG-DNA on Toll-like receptor 9 studied by AFM. TRAUNER Verlag TRAUNER Verlag
Academic anthology/Conference proceedings
Nilsen, Nadra; Espevik, Terje; Lien, Egil. (2008) Toll-like receptor 2 expression, regulation and signaling. Tapir Akademisk Forlag Tapir Akademisk Forlag
Doctoral dissertation
Halaas, Øyvind; Husebye, Harald; Stenmark, Harald; Espevik, Terje. (2008) Intracellular Trafficing of Toll-like Receptors. CRC Press
Academic chapter/article/Conference paper

2007

Latz, E; Verma, Anjali; Visintin, A; Gong, Mei; Sirois, CM; Klein, Dionne. (2007) Corrigendum: Ligand-induced conformational changes allosterically activate Toll-like receptor 9. International Immunology
Academic article
Halaas, Øyvind; Husebye, Harald; Espevik, Terje. (2007) The journey of Toll-like receptors in the cell. Advances in Experimental Medicine and Biology
Academic article
Latz, Eicke; Verma, Anjali; Visintin, A; Gong, Mei; Sirois, Cherilyn m.; Klein, Dionne. (2007) Ligand-induced conformational changes allosterically activate Toll-like receptor 9. Nature Immunology
Academic article
Tunheim, G; Thompson, KM; Fredriksen, AB; Espevik, Terje; Schjetne, KW; Bogen, B. (2007) Human receptors of innate immunity (CD14, TLR2) are promising targets for novel recombinant immunoglobulin-based vaccine candidates. Vaccine
Academic article

2006

Rokstad, Anne Mari Aukan; Donati, Ivan; Borgogna, Massimiliano; Oberholzer, José; Strand, Berit Løkensgard; Espevik, Terje. (2006) Cell-compatible covalently reinforced beads obtained from a chemoenzymatically engineered alginate. Biomaterials
Academic article
Husebye, Harald; Halaas, Øyvind; Stenmark, Harald; Tunheim, G; Sandanger, Øystein; Bogen, B. (2006) Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity. EMBO Journal
Academic article
Espevik, Terje; Lien, Egil. (2006) Vaksine mot svartedauen. Gemini
Popular scientific article
Espevik, Terje; Skjåk-Bræk, Gudmund. (2006) Friskere fisk med tang og tare. Gemini
Popular scientific article
Ueland, Thor; Espevik, Terje; Kjekshus, John; Gullestad, Lars; Omland, Torbjørn; Squire, Iain B.. (2006) Mannose binding lectin and soluble Toll-lilke receptor 2 in heart failure following acute myocardial infarction. Journal of Cardiac Failure
Academic article
Bohnhorst, Janne Øvrebø; Rasmussen, T; Moen, Siv H; Fløttum, Marianne; Knudsen, L; Børset, Magne. (2006) Toll-like receptors mediate proliferation and survival of multiple myeloma cells. Leukemia
Academic article
Nilsen, Asbjørn Magne; Vik, Randi; Espevik, Terje. (2006) BeLPT testing Karmøy. Undervegsrapport 1. Januar 2006. Norges Teknisk-Naturvitenskapelige Universitet
Report
Nilsen, Asbjørn Magne; Vik, Randi; Espevik, Terje. (2006) Be-LPT testing at Hydro Aluminium Karmøy AS. Final Report. June 2006. Norwegian University of Science and Technology
Report
Nilsen, Asbjørn Magne; Vik, Randi; Espevik, Terje. (2006) Be-LPT testing Karmøy. Undervegsrapport 4. April 2006. Norges Teknisk-Naturvitenskapelige Universitet
Report
Nilsen, Asbjørn Magne; Vik, Randi; Espevik, Terje. (2006) Be-LPT testing Karmøy. Undervegsrapport 3. Mars 2006. Norges Teknisk-Naturvitenskapelige Universitet
Report
Nilsen, Asbjørn Magne; Vik, Randi; Espevik, Terje. (2006) Be-LPT testing Karmøy. Undervegsrapport 2. Februar 2006. Norges Teknisk-Naturvitenskapelige Universitet
Report
Johnsen, Ingvild Bjellmo; Nguyen, Thank Thuy Thi; Ringdal, Monika; Tryggestad, AM; Bakke, Oddmund; Lien, Egil. (2006) Toll-like receptor 3 associates with c-Src tyrosine kinase on endosomes to initiate antiviral signaling. EMBO Journal
Academic article

2005

Mancuso, Guiseppe; Midiri, A; Biondo, Carmelo; Beninati, C.; Gambuzza, M; Macri, D. (2005) Bacteroides fragilis-derived lipopolysaccharide produces cell activation and lethal toxicity via toll-like receptor 4. Infection and Immunity
Academic article
Manukyan, M; Triantafilou, K; Triantafilou, M; Mackie, A; Nilsen, Nadra Jesmine; Espevik, Terje. (2005) Binding of lipopeptide to CD14 induces physical proximity of CD14, TLR2 and TLR1. European Journal of Immunology
Academic article
Heggelund, L; Mollnes, TE; Espevik, Terje; Muller, F; Kristiansen, KI; Aukrust, P. (2005) Modulatory effect of mannose-binding lectin on cytokine responses: roles in HIV infection. European Journal of Clinical Investigation
Academic article
Dybdahl, Brit; Slørdahl, Stig Arild; Waage, Anders; Kierulf, Peter; Espevik, Terje; Sundan, Anders. (2005) Myocardial ischaemia and the inflammatory response: release of heat shock protein 70 after myocardial infarction. Heart
Academic article
Rokstad, Anne Mari Aukan; Bjerkvig, Rolf; Espevik, Terje; Lund-Johansen, M. (2005) Applications of Cell Immobilisation Biotechnology, Focus on Biotechnology. Book chapter: Cell encapsulation therapy for malignant gliomas. Springer Springer
Academic anthology/Conference proceedings
Heggelund, L; Mollnes, TE; Espevik, Terje; Muller, F; Kristiansen, KI; Aukrust, P. (2005) Modulatory effect of mannose-binding lectin on cytokine resposes: possible roles in HIV infection. European Journal of Clinical Investigation
Academic article
Heggelund, Lars; Mollnes, Tom Eirik; Espevik, Terje; Muller, Fredrik; Kristiansen, Knut Ivan; Aukrust, Pål. (2005) Modulatory effect of mannose-binding lectin on cytokine responses: possible roles in HIV infection. European Journal of Clinical Investigation
Academic article

2004

Frantisek, S; Latz, E; Re, F; Mandell, L; Repik, G; Golenbock, D. (2004) Importance of extra-and intracellular domains of TLR1 and TLR2 receptors in NF-kappa B signaling. Tissue Antigens
Abstract
Heggelund, L; Flo, Trude Helen; Berg, K.; Lien, E; Espevik, Terje. (2004) Soluble toll-like receptor 2 in HIV infection: association with disease progression. AIDS (London)
Academic article
Halaas, Øyvind; Liabakk, Nina-Beate; Vik, Randi; Beninati, C; Henneke, P; Sundan, Anders. (2004) Monocytes stimulated with group B Streptococci or interferons release tumour necrosis factor-related apoptosis-inducing ligand. Scandinavian Journal of Immunology
Academic article
Nilsen, N; Nonstad, U; Khan, N; Knetter, Cathrine; Akira, S; Sundan, Anders. (2004) Lipopolysaccharide and double-stranded RNA up-regulate toll-like receptor 2 independently of myeloid differentiation factor 88. Journal of Biological Chemistry
Academic article
Dybdahl, Brit; Wahba, Alexander; Haaverstad, Rune; Kirkeby-Garstad, I.; Kierulf, P; Espevik, Terje. (2004) On-pump versus off-pump coronary artery bypass grafting: more heat-shock protein 70 is released after on-pump surgery. European Journal of Cardio-Thoracic Surgery
Academic article
Liabakk, Nina-Beate; Espevik, Terje. (2004) Monoclonal antibodies against TRAIL. Vitamines and Hormones
Academic article
Latz, E; Visintin, A; Espevik, Terje; Golenbock, DT. (2004) Mechanisms of TLR9 activation. Journal of Endotoxin Research
Academic article
Latz, E; Schoenemeyer, A; Visintin, A; Fitzgerald, KA; Monks, BG; Knetter, Cathrine. (2004) TLR9 signals after translocating from the ER to CpG DNA in the lysosome. Nature Immunology
Academic article
Heggelund, L; Muller, F; Lien, E; Yndestad, A; Ueland, T; Kristiansen, KI. (2004) Increased expression of Toll-like receptor 2 on monocytes in HIV infection: Possible roles in inflammation and viral replication. Clinical Infectious Diseases
Academic article
Espevik, Terje. (2004) Tolerance induced by the lipopeptide Pam3Cys is due to ablation of IL-1R-associated kinase-1. Journal of Immunology
Academic article
Heggelund, L; Damås, Jan Kristian; Damas, JK; Yndestad, A; Holm, AM; Muller, F. (2004) Stimulation of toll-like receptor 2 in mononuclear cells from HIV-infected patients induces chemokine responses: possible pathogenic consequences. Clinical and Experimental Immunology
Academic article
Dybdahl, Brit; Wahba, Alexander; Haaverstad, R; Kirkeby-Garstad, Idar; Kierulf, Peter; Espevik, Terje. (2004) On-pump versus off-pump coronary artery bypass grafting: more heat-shock protein 70 is released after on-pump surgery. European Journal of Cardio-Thoracic Surgery
Academic article
Heggelund, Lars; Flo, T; Berg, K; Lien, T; Mollnes, TE; Ueland, Thor. (2004) Soluble toll-like receptor 2 in HIV infection: association with disease progression. AIDS (London)
Academic article
Nilsen, Nadra; Nonstad, Unni; Kahn, Naseema; Knetter, Cathrine; Akira, Shizuo; Sundan, Anders. (2004) Lipopolysaccharide and Double-stranded RNA Up-regulate Toll-like Receptor 2 Independently of Myeloid Differentiation Factor 88. Journal of Biological Chemistry
Academic article

2003

Latz, E; Visintin, A; Lien, E; Fitzgerald, KA; Espevik, Terje; Golenbock, DT. (2003) The LPS receptor generates inflammatory signals from the cell surface. Journal of Endotoxin Research
Academic article
Schjetne, KW; Thompson, Keith; Fleckenstein, Burkhard; Aarvak, Tanja; Flo, T. H.; Iversen, Jens Gustav. (2003) Cutting edge: Link between innate and adaptive immunity: toll like receptor 2 (TLR 2) captures antigen for MHC class II presentation to CD4+ T cell responses. Journal of Immunology
Academic article
Strand, Berit Løkensgard; Mørch, Yrr Asbjørg; Espevik, Terje; Skjåk-Bræk, Gudmund. (2003) Visualization of alginate-poly-L-lysine-alginate microcapsules by confocal laser scanning microscopy. Biotechnology and Bioengineering
Academic article
Strand, Berit Løkensgard; Mørch, Yrr Asbjørg; Syvertsen, Kjersti R.; Espevik, Terje; Skjåk-Bræk, Gudmund. (2003) Microcapsules made by enzymatically tailored alginate. Journal of Biomedical Materials Research
Academic article
Espevik, Terje; Latz, Eicke; Lien, Egil; Monks, Brian G.. (2003) Cell distribution and functions of Toll-like receptor 4 studied by fluorescent gene constructs. Scandinavian Journal of Infectious Diseases
Academic article
Mori, Y; Yoshimura, A; Ukai, T; Lien, Egil; Espevik, Terje; Hara, Y. (2003) Immunohistochemical localization of Toll-like receptors 2 and 4 in gingival tissue from patients with periodontitis. Oral Microbiology and Immunology
Academic article
Adib-Conquy, M; Moine, P; Asehnoune, K; Edouard, A; Espevik, Terje; Miyake, K. (2003) Toll-like receptor-mediated tumor necrosis factor and interleukin-10 production differ during systemic inflammation. American Journal of Respiratory and Critical Care Medicine
Academic article
Visintin, A; Latz, Eicke; Monks, Brian G.; Espevik, Terje; Golenbock, Douglas T.. (2003) Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction. Journal of Biological Chemistry
Academic article
Schjetne, KW; Thompson, KM; Nilsen, Nadra; Flo, Trude Helen; Fleckenstein, B; Iversen, JG. (2003) Cutting edge: link between innate and adaptive immunity: Toll-like receptor 2 internalizes antigen for presentation to CD4+ T cells and could be an efficient vaccine target. Journal of Immunology
Academic article
Sandor, F; Latz, Eicke; Mandell, L; Repik, G; Golenbock, Douglas T.; Espevik, Terje. (2003) Importance of extra- and intracellular domains of TLR1 and TLR2 in NFkappa B signaling. Journal of Cell Biology
Academic article
Rokstad, Anne Mari Aukan; Strand, Berit Løkensgard; Rian, K.; Steinkjer, Bjørg; Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund. (2003) Evaluation of different types of alginate microcapsules as bioreactors for producing endostatin. Cell Transplantation
Academic article

2002

Espevik, Terje. (2002) På väg att knäcka hjärntumörer. Länstidningen, Østersund, Sverige
Feature article
Dybdahl, Brit; Lien, Egil; Flo, Trude Helen; Espevik, Terje; Sundan, Anders; Wahba, Alexander. (2002) Heat Shock Proteins and Endotoxin Combined as a Trigger for Inflammatory Cytokine Release During Cardiopulmonary Bypass: A Possible Third Way? Letter til artikkel. Circulation
Academic article
Rokstad, Anne Mari Aukan; Holtan, Synnøve; Strand, Berit Løkensgard; Steinkjer, Bjørg; Ryan, Liv; Kulseng, Bård Eirik. (2002) Microencapsulation of cells producing therapeutic proteins: Optimizing cell growth and secretion. Cell Transplantation
Academic article
Flo, Trude Helen; Ryan, Liv; Latz, Eicke; Takeuchi, Osamu; Monks, Brian G.; Lien, Egil. (2002) Involvement of toll-like receptor (TLR) 2 and TLR4 in cell activation by mannuronic acid polymers. Journal of Biological Chemistry
Academic article
Tamai, Riyoko; Sakuta, T; Matsushita, K; Torii, M; Takeuchi, Osamu; Akira, Shizuo. (2002) Human gingival CD14(+) fibroblasts primed with gamma interferon increase production of interleukin-8 in response to lipopolysaccharide through up-regulation of membrane CD14 and MyD88 mRNA expression. Infection and Immunity
Academic article
Latz, Eicke; Visintin, A; Lien, Egil; Fitzgerald, KA; Monks, Brian G.; Kurt-Jones, EA. (2002) Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the Toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction. Journal of Biological Chemistry
Academic article
van der Kleij, D; Latz, Eicke; Brouwers, JF; Kruize, YC; Schmitz, M; Kurt-Jones, EA. (2002) A novel host-parasite lipid cross-talk. Schistosomal lyso-phosphatidylserine activates Toll-like recepytor 2 and affects immune polarization. Journal of Biological Chemistry
Academic article
Liabakk, Nina-Beate; Sundan, Anders; Torp, Sverre Helge; Aukrust, Pål; Frøland, Stig Sophus; Espevik, Terje. (2002) Development, characterization and use of monoclonal antibodies against sTRAIL measurement of sTRAIL by ELISA. Journal of Immunological Methods (JIM)
Academic article
Belge, KU; Dayyani, F; Horelt, A; Siedlar, M; Frankenberger, M; Frankenberger, B. (2002) The proinflammatory CD14+CD16+DR++ monocytes are a major source of TNF. Journal of Immunology
Academic article
Dybdahl, Brit; Wahba, Alexander; Lien, Egil; Flo, Trude Helen; Waage, Anders; Sellevold, Olav F Münter. (2002) Inflammatory response after open heart surgery: release of heat-shock protein 70 and signaling through toll-like receptor-4. Circulation
Academic article
Ellingsen, E.A.; Morath, S; Flo, Trude Helen; Schromm, Andra; Hartung, T; Thiemermann, C. (2002) Induction of cytokine production in human T cells and monocytes by highly purified lipoteichoic acid: involvement of Toll-like receptors and CD14. Medical Science Monitor
Academic article
Strand, Berit Løkensgard; Gåserød, Olav; Kulseng, Bård Eirik; Espevik, Terje; Skjåk-Bræk, Gudmund. (2002) Alginate-polylysine-alginate microcapsules – effect of size reduction on capsule properties. Journal of Microencapsulation
Academic article

2001

Lien, Egil; Chow, Jesse C.; Hawkins, Lynn D.; McGuinness, Pamela D.; Miyake, Kensuke; Espevik, Terje. (2001) A novel synthetic acyclic lipid A-like agonist activates cells via the lipopolysaccharide/Toll-like receptor 4 signaling pathway. Journal of Biological Chemistry
Academic article
Liabakk, Nina-Beate; Waage, Anders; Lien, Egil; Stenvik, Jørgen; Espevik, Terje. (2001) Cytokine bioassays. Methods in Molecular Medicine
Academic article
Strand, Berit Løkensgard; Ryan, Liv; Int Veld, Peter; Kulseng, Bård Eirik; Rokstad, Anne Mari Aukan; Skjåk-Bræk, Gudmund. (2001) Poly-L-Lysine Induces Fibrosis on Alginate Microcapsules via the Induction of Cytokines. Cell Transplantation
Academic article
Flo, Trude Helen; Ryan, Liv; Kilaas, L; Skjåk-Bræk, Gudmund; Ingalls, Robin; Sundan, Anders. (2001) The involvement of CD14 and beta2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers. Infection and Immunity
Academic article
Wang, J; Warris, A; Ellingsen, E.A.; Jorgensen, P.F.; Flo, Trude Helen; Espevik, Terje. (2001) Involvement of CD14 and toll-like receptors in activation of human monocytes by Aspergillus fumigatus hyphae. Infection and Immunity
Academic article
Liabakk, Nina-Beate; Sundan, Anders; Torp, Sverre Helge; Aukrust, Pål; Frøland, Stig; Espevik, Terje. (2001) Development, characterization and use of monclonal antibodies against Strail: Measurement of Strail by Elisa. Journal of Immunological Methods (JIM)
Academic article
Henneke, Philipp; Takeuchi, Osamu; van Strijp, JA; Guttormsen, HK; Smith, JA; Schromm, Andra. (2001) Novel engagement of CD14 and multiple toll-like receptors by group B streptococci. Journal of Immunology
Academic article
Flo, Trude Helen; Halaas, Øyvind; Torp, Sverre Helge; Ryan, Liv; Lien, Egil; Dybdahl, Brit. (2001) Differential expression of Toll-like receptor 2 in human cells. Journal of Leukocyte Biology
Academic article
Sugawara, Shunji; Yang, Shuhua; Iki, Koichi; Hatakeyama, Junko; Tamai, Riyoko; Takeuchi, Osamu. (2001) Monocytic cell activation by nonendotoxic glycoprotein from Prevotella intermedia ATCC 25611 is mediated by Toll-like receptor 2. Infection and Immunity
Academic article
Rokstad, Anne Mari Aukan; Kulseng, Bård Eirik; Strand, Berit Løkensgard; Skjåk-Bræk, Gudmund; Espevik, Terje. (2001) Transplantation of alginate microcapsules with proliferating cells in mice. Capsular overgrowth and suvival of encapsulated cells of mice and human origin. Annals of the New York Academy of Sciences
Academic article
Iversen, Ann-Charlotte; Sundan, Anders; Espevik, Terje. (2001) IFN-alpha(2b) and IFN-beta induce TRAIL-mediated NK cell cytotoxicity. The FASEB Journal
Abstract
Jenssen, Jon A; Espevik, Terje. (2001) Cellebiologisk metode for å påvise biologisk aktivitet av svevestøv. SINTEF Rapport
Report

2000

Skjåk-Bræk, Gudmund; Flo, Trude Helen; Halaas, Øyvind; Espevik, Terje. (2000) Immune stimulating properties of di-equatorially beta(1->4) linked poly-uronides. Proceedings of the Phytochemical Society of Europe
Academic article
Flo, Trude Helen; Halaas, Øyvind; Lien, Egil; Ryan, Liv; Teti, Guiseppe; Golenbock, Douglas T.. (2000) Human Toll-like Receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide. Journal of Immunology
Academic article
Cuzzola, Maria; Mancuso, Guiseppe; Beninati, Concetta; Biondo, Carmelo; von Hunolstein, Christina; Orefici, Graziella. (2000) Human monocyte receptors involved in tumor necrosis factor responses to group B streptococcal products. Infection and Immunity
Academic article
Cuzzola, M.; Mancuso, G.; Beninati, C.; Biondo, C.; Genovese, F.; Tomasello, F.. (2000) _B2 integrins are involved in cytokine responses to whole gram-positive bacteria. Journal of Immunology
Academic article
Flo, Trude Helen; Ryan, Liv; Kilaas, Lars; Skjåk-Bræk, Gudmund; Ingalls, Robin R.A; Sundan, Anders. (2000) Involvement of CD14 and _B2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers. Infection and Immunity
Academic article
Falch, Berit H.; Espevik, Terje; Ryan, Liv; Stokke, Bjørn Torger. (2000) The cytokine stimulating activity of (1->3)-_B-D-glucans is dependent on the triple helix conformation. Carbohydrate Research
Academic article
Flo, T.H.; Ryan, L.; Kilaas, L.; Skjåk-Bræk, Gudmund; Ingalls, R.R.; Sundan, A.. (2000) Involvement of CD14 and beta2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers. Infection and Immunity
Academic article
Lien, E.; Espevik, Terje. (2000) Toll-lignende reseptorer - kroppens sensorer for infeksjon. NBS-nytt
Popular scientific article
Espevik, Terje; Waage, Anders; Sundan, A.. (2000) Summary of the 8 th International TNF Congress. Trondheim. NBS-nytt
Non-fiction book
Espevik, Terje; Waage, Anders; Sundan, Anders. (2000) Summary of the 8th International TNF Congress, Trondheim, May 14-18, 2000. NBS-nytt
Report

1994

Waage, A.; Halstensen, Alfred; Espevik, T.; Brandtzæg, P.. (1994) Cytokines in meningococcal disease. Baillière's Clinical Infectious Diseases
Academic article
Halgunset, J; Johnsen, H; Kjøllesdal, AM; Qvigstad, E; Espevik, Terje; Austgulen, Rigmor. (1994) Normal parturition at term is associated with subtle inflammatory reactions in-utero. European Journal of Obstetrics, Gynecology, and Reproductive Biology
Academic article
Brekke, OL; Espevik, Terje; Bjerve, Kristian S. (1994) Butylated Hydroxyanisole Inhibits Tumor Necrosis Factor induced Cytotoxicity and Arachidonic Acid Release. Lipids
Academic article

1993

Austgulen, Rigmor; Liabakk, N-B; Richardsen, W; Rahimipoor, S; Vatn, I; Espevik, Terje. (1993) Serum levels of soluble TNF receptors are influenced by gestational age and delivery in normal pregnancy. Placenta
Abstract
Waage, A.; Halstensen, Alfred; Espevik, T.; Brandtzæg, P.. (1993) Compartmentalization of the TNF and IL-6 in meningitis and septic shock. Mediators of Inflammation
Academic article
Austgulen, Rigmor; Liabakk, N-B; Lien, E; Espevik, Terje. (1993) Increased levels of soluble TNF-alpha receptors in serum from pregnant women, and in serum and urine samples from newborns. Pediatric Research
Academic article
Liabakk, N-B; Lien, E; Sundan, A; Sunde, A; Austgulen, Rigmor; Espevik, Terje. (1993) High concentrations of the soluble p55 tumor necrosis factor receptor in human seminal plasma. Human Reproduction
Academic article
Austgulen, Rigmor; Kjøllesdal, AM; Johnsen, H; Liabakk, N-B; Espevik, Terje. (1993) Soluble receptors for tumor necrosis factor: occurence in association with normal delivery at term. Obstetrics and Gynecology
Academic article
Naume, Bjørn; Iversen, Ann-Charlotte; Johnsen, Ann-Charlotte; Espevik, Terje; Sundan, Anders. (1993) Gene expression and secretion of cytokines and cytokine receptors from hihgly purified CD56+ natural killer cells stimulated with interleukin-2, interleukin-7 and interleukin-12. European Journal of Immunology
Academic article
Austgulen, Rigmor; Naume, B; Johnson, A-C; Espevik, Terje; Sundan, A. (1993) Gene expression and secretion of cytokines and cytokines from highly purified CD56* natural killer cells stimulated with interleukin-2, interleukin-7 and interleukin-12. European Journal of Immunology
Academic article

1992

Soon-Shong, P.; Feldman, E.; Nelson, R.; Komtebedde, J.; Smidsrød, Olav; Skjåk-Bræk, Gudmund. (1992) Successful reversal of spontaneous diabetes in dogs by intraperitonal microencapsulated islets. Transplantation
Academic article
Brandtzæg, P.; Halstensen, Alfred; Kierulf, P.; Espevik, T.; Waage, A.. (1992) Molecular mechanisms in the compartmentalized inflammatory response presenting as meningococcal meningitis or septic shock. Microbial Pathogenesis
Academic article
Austgulen, Rigmor; Espevik, Terje; Mecsei, R; Scott, H. (1992) Expression of receptors for tumor necrosis factor in human placenta at term. Acta Obstetricia et Gynecologica Scandinavica
Academic article
Austgulen, Rigmor; Liabakk, N-B; Espevik, Terje. (1992) Sekresjon av løselige reseptorer for tumor nekrose faktor - en immunologisk buffermekanisme under svangerskap?. Tidsskrift for Den norske legeforening (Tidsskriftet)
Academic article
Austgulen, Rigmor; Liabakk, NB; Brockhaus, M; Espevik, Terje. (1992) Soluble TNF receptors in amniotic fluid and in urine from pregnant women. Journal of Reproductive Immunology
Academic article
Brekke, OL; Espevik, Terje; Bardal, Tora; Bjerve, Kristian S. (1992) Effects of n-3 and n-6 fatty acids on Tumor Necrosis Factor cytotoxicity in WEHI fibrosarcoma cells. Lipids
Academic article
Brekke, OL; Shalaby, MR; Sundan, Anders; Espevik, Terje; Bjerve, Kristian S. (1992) Butylated hydroxyanisol specifically inhibits Tumor Necrosis Factor induced cytotoxicity and growth enhancement. Cytokine
Academic article
Waage, A.; Halstensen, Alfred; Brandtzæg, P.; Espevik, T.. (1992) TNF in serum in patients with bacterial infections.
Academic chapter/article/Conference paper

1991

Austgulen, Rigmor; Liabakk, N-B; Scott, H; Brockhaus, M; Espevik, Terje. (1991) Soluble TNF receptors in urine and in amniotic fluid from pregnant women. Placenta
Abstract
Waage, A.; Brandtzæg, P.; Espevik, T.; Halstensen, Alfred. (1991) Current understanding of the pathogenesis of gram negative shock. Infectious Disease Clinics of North America
Academic article

1988

Nissen-Meyer, J; Austgulen, Rigmor; Espevik, Terje. (1988) Synergistic growth inhibitory activity of tumor necrosis factor and interferon-alpha: contribution to the monocyte-derived cytostatic activity towards human leukemia K562 cells. Scandinavian Journal of Immunology
Academic article
Nissen-Meyer, J; Hofsli, E; Espevik, Terje; Austgulen, Rigmor. (1988) Involvement of tumor necrosis factor in cytotoxicity mediated by human monocytes. Natural immunity and cell growth regulation
Academic article

1987

Austgulen, Rigmor; Espevik, Terje; Nissen-Meyer, J. (1987) Fibroblast growth stimulatory activity from human monocytes: The contribution of tumor necrosis factor. Scandinavian Journal of Immunology
Academic article
Nissen-Meyer, J; Austgulen, Rigmor; Espevik, Terje. (1987) Comparison of recombinant tumor necrosis factor and the monocyte-derived cytotoxic factor (CF) which is involved in the monocyte-mediated cytotoxicity. Cancer Research
Academic article
Austgulen, Rigmor; Espevik, Terje; Degree, M. (1987) Monocyte-derived influence on growth of normal human fibroblasts: The contribution of tumor necrosis factor to growth inhibition. Scandinavian Journal of Immunology
Academic article
Bjerve, Kristian S; Espevik, Terje; Kildahl-Andersen, O; Nissen-Meyer, J. (1987) Effect of free fatty acids on the cytolytic activity of tumor necrosis factor/¬monocyte-derived cytotoxic factor. APMIS - Journal of Pathologiy, Microbiology and Immunology
Academic article

1986

Austgulen, Rigmor; Kildahl-Andersen, O; Espevik, Terje. (1986) Monocyte-mediated drug-dependent cellular cytotoxicity: Effects of different WEHI 164 target cell lines. Cancer Immunology and Immunotherapy
Academic article
Austgulen, Rigmor; Espevik, Terje; Hammerstrøm, J; Nissen-Meyer, J. (1986) Role of monocyte cytotoxic factor in cytolysis of actinomycin D treated WEHI 164 cells mediated by freshly isolated human adherent mononuclear blood cells. Cancer Research
Academic article
Austgulen, Rigmor; Hammerstrøm , J; Espevik, Terje; Nissen-Meyer, J. (1986) Human monocyte cytotoxic factor mediates cytolysis of WEHI 164 cells. Cellular Immunology
Academic article

Journal publications

Zhang, Boyao; Orning, Pontus; Lehman, Jesse W.; Dinis, Alexandre; Torres-Ulloa, Leslie; Elling, Roland. (2025) Raver1 links Ripk1 RNA splicing to caspase-8-mediated pyroptotic cell death, inflammation, and pathogen resistance. Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Academic article
Mestvedt, Ingvild Bergdal; Menu, Eline; Misund, Kristine; Slørdahl, Tobias Schmidt; Rasheed, Kashif; Wolowczyk, Camilla Izabel. (2025) Novel SLAMF1-derived peptide induces apoptosis in multiple myeloma cells by targeting IRF4 transcription factor for degradation. bioRxiv
Academic article
Olsen, Maria Belland; Kong, Xiang Yi; Louwe, Maria; Lauritzen, Knut Husø; Schanke, Ylva; Kaasbøll, Ole Jørgen. (2024) SLAMF1-derived peptide exhibits cardio protection after permanent left anterior descending artery ligation in mice. Frontiers in Immunology
Academic article
Fageräng, Beatrice Linnea Christina; Cyranka, Leon; Schjalm, Camilla; Ekholt, Karin; Larsen, Carina Sandem; Heinzelbecker, Julia. (2024) The function of the complement system remains fully intact throughout the course of allogeneic stem cell transplantation. Frontiers in Immunology
Academic article
Nilsen, Kaja Elisabeth; Zhang, Boyao; Skjesol, Astrid; Ryan, Liv; Vagle, Hilde; Bøe, Maren Helene. (2023) Peptide derived from SLAMF1 prevents TLR4-mediated inflammation in vitro and in vivo. Life Science Alliance (LSA)
Academic article
Lentini, Germana; Famà, Agata; De Gaetano, Giuseppe Valerio; Coppolino, Francesco; Mahjoub, Ahlem Khachroub; Ryan, Liv. (2023) Caspase-8 inhibition improves the outcome of bacterial infections in mice by promoting neutrophil activation. Cell Reports Medicine
Academic article
Bjerkhaug, Aline; Granslo, Hildegunn Norbakken; Cavanagh, Jorunn Pauline; Høiland, Ina Isabella; Ludviksen, Judith K; Lau, Corinna. (2023) Dual inhibition of complement C5 and CD14 attenuates inflammation in a cord blood model. Pediatric Research
Academic article
Pinto, Sneha M.; Subbannayya, Yashwanth; Kim, Hera; Hagen, Lars; Górna, Maria W; Nieminen, Anni I.. (2022) Multi-OMICs landscape of SARS-CoV-2-induced host responses in human lung epithelial cells. iScience
Academic article
Nilsen, Kaja Elisabeth; Skjesol, Astrid; Kojen, June Frengen; Espevik, Terje; Stenvik, Jørgen; Yurchenko, Mariya. (2022) TIRAP/Mal Positively Regulates TLR8‐Mediated Signaling via IRF5 in Human Cells. Biomedicines
Academic article
Johnson, Christina; Quach, Huy Quang; Lau, Corinna; Ekholt, Karin; Espevik, Terje; Woodruff, Trent M.. (2022) Thrombin Differentially Modulates the Acute Inflammatory Response to Escherichia coli and Staphylococcus aureus in Human Whole Blood. Journal of Immunology
Academic article
Islam, Rakibul; Islam, Mohammad Mirazul; Nilsson, Per H.; Mohlin, Camilla; Hagen, Kjersti Thorvaldsen; Paschalis, Eleftherios I.. (2021) Combined blockade of complement C5 and TLR co-receptor CD14 synergistically inhibits pig-to-human corneal xenograft induced innate inflammatory responses. Acta Biomaterialia
Academic article
Kim, Hera; Subbannayya, Yashwanth; Humphries, Fiachra; Skjesol, Astrid; Pinto, Sneha M.; Giambelluca, Miriam. (2021) UMP-CMP kinase 2 gene expression in macrophages is dependent on the IRF3-IFNAR signaling axis. PLOS ONE
Academic article
Trifonov, Lena; Yurchenko, Mariya; Skjesol, Astrid; Cohen, Guy; Espevik, Terje; Korshin, Edward E.. (2021) Benzyl-para-di-[5-methyl-4-(n-octylamino) pyrimidin-2(1H)one] as an interferon beta (IFN-β) modulator. Molecular diversity
Academic article
Niyonzima, Nathalie; Rahman, Jubayer; Kunz, Natalie; West, Erin; Freiwald, Tilo; Desai, Jigar V.. (2021) Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation . Science immunology
Academic article
Ehrnstrøm, Birgitta; Kojen, June Frengen; Giambelluca, Miriam; Ryan, Liv; Moen, Siv Helen; Hu, Zhenyi. (2020) TLR8 and complement C5 induce cytokine release and thrombin activation in human whole blood challenged with Gram-positive bacteria. Journal of Leukocyte Biology
Academic article
Niyonzima, Nathalie; Bakke, Siril Skaret; Gregersen, Ida; Holm, Sverre; Sandanger, Øystein; Orrem, Hilde Lang. (2020) Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis. EBioMedicine
Academic article
Skjesol, Astrid; Yurchenko, Mariya; Bösl, Korbinian; Gravastrand, Caroline S.; Nilsen, Kaja Elisabeth; Grøvdal, Lene Melsæther. (2019) The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2. PLoS Pathogens
Academic article
Pilely, Katrine; Bakke, Siril Skaret; Palarasah, Yaseelan; Skjoedt, Mikkel-Ole; Bartels, Emil D.; Espevik, Terje. (2019) Alpha-cyclodextrin inhibits cholesterol crystal-induced complement-mediated inflammation: A potential new compound for treatment of atherosclerosis. Atherosclerosis
Academic article
Lau, Corinna; McAdam, Martin Berner; Bergseth, Grete; Grevys, Algirdas; Bruun, Jack-Ansgar; Ludviksen, Judith K. (2019) NHDL, a recombinant VL/VH hybrid antibody control for IgG2/4 antibodies. mAbs
Academic article
Christensen, Jacob J.; Bakke, Siril Skaret; Ulven, Stine Marie; Retterstøl, Kjetil; Henriksen, Tore; Bollerslev, Jens. (2019) Serum Omega-6 Fatty Acids and Immunology-Related Gene Expression in Peripheral Blood Mononuclear Cells: A Cross-Sectional Analysis in Healthy Children. Molecular Nutrition & Food Research
Academic article
Skjeflo, Espen Waage; Christiansen, Dorte; Landsem, Anne; Stenvik, Jørgen; Woodruff, T. M.; Espevik, Terje. (2019) Phagocytosis of live and dead Escherichia coli and Staphylococcus aureus in human whole blood is markedly reduced by combined inhibition of C5aR1 and CD14. Molecular Immunology
Academic article
Moen, Siv Helen; Ehrnstrøm, Birgitta; Kojen, June Frengen; Yurchenko, Mariya; Beckwith, Kai Sandvold; Afset, Jan Egil. (2019) Human Toll-like receptor 8 (TLR8) is an important sensor of pyogenic bacteria, and is attenuated by cell surface TLR signaling. Frontiers in Immunology
Academic article
Gravastrand, Caroline S.; Steinkjer, Bjørg; Halvorsen, Bente; Landsem, Anne; Skjelland, Mona; Jacobsen, Eva Astrid. (2019) Cholesterol Crystals Induce coagulation Activation through Complement-Dependent Expression of Monocytic Tissue Factor. Journal of Immunology
Academic article
Narverud, Ingunn; Christensen, Jacob J.; Bakke, Siril Skaret; Ulven, Stine Marie; Rundblad, Amanda; Aukrust, Pål. (2019) Profiling of immune-related gene expression in children with familial hypercholesterolaemia. Journal of Internal Medicine
Academic article
Lunde, Ngoc Dieu Nguyen; Gregersen, Ida; Ueland, Thor; Shetelig, Christian; Holm, Sverre; Kong, Xiang Yi. (2019) Legumain is upregulated in acute cardiovascular events and associated with improved outcome – potentially related to anti-inflammatory effects on macrophages. Atherosclerosis
Academic article
Thomas, Anub Mathew; Gerogianni, Alexandra; McAdam, Martin Berner; Fløisand, Yngvar; Lau, Corinna; Espevik, Terje. (2019) Complement component C5 and TLR molecule CD14 mediate heme-induced thromboinflammation in human blood. Journal of Immunology
Academic article
Skjeflo, Espen Waage; Christiansen, Dorte; Fure, Hilde; Ludviksen, Judith K; Woodruff, Trent M.; Espevik, Terje. (2018) Staphylococcus aureus-induced complement activation promotes tissue factor-mediated coagulation. Journal of Thrombosis and Haemostasis
Academic article
Kleveland, Ola; Ueland, Thor; Kunszt, Gabor; Bratlie, Marte; Yndestad, Arne; Broch, Kaspar. (2018) Interleukin-6 receptor inhibition with tocilizumab induces a selective and substantial increase in plasma IP-10 and MIP-1β in non-ST-elevation myocardial infarction. International Journal of Cardiology
Academic article
Thomas, Anub Mathew; Schjalm, Camilla; Nilsson, Per; Lindenskov, Paal Helge H.; Rørtveit, Runa; Solberg, Rønnaug. (2018) Combined Inhibition of C5 and CD14 Attenuates Systemic Inflammation in a Piglet Model of Meconium Aspiration Syndrome. Neonatology
Academic article
Landsem, Anne; Fure, Hilde; Ludviksen, Judith K; Christiansen, Dorte; Lau, Corinna; Mathisen, Monica Dammen. (2018) Complement component 5 does not interfere with physiological hemostasis but is essential for Escherichia coli-induced coagulation accompanied by Toll-like receptor 4. Clinical and Experimental Immunology
Academic article
Orrem, Hilde Lang; Nilsson, Per; Pischke, Søren Erik; Kleveland, Ola; Yndestad, Arne; Ekholt, Karin. (2018) IL-6 receptor inhibition by tocilizumab attenuated expression of C5a receptor 1 and 2 in non-ST-elevation myocardial infarction. Frontiers in Immunology
Academic article
Yurchenko, Mariya; Skjesol, Astrid; Ryan, Liv; Richard, Gabriel Mary; Kandasamy, Richard Kumaran; Wang, Ninghai. (2018) SLA MF1 is required for TLR4-mediated TRAM-TRIF- dependent signaling in human macrophages. Journal of Cell Biology
Academic article
Christ, Anette; Günther, Patrick; Lauterbach, Mario A.R.; Duewell, Peter; Biswas, Debjani; Pelka, Karin. (2018) Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming. Cell
Academic article
Nejati Moharrami, Neda; Tande, Erlend Bjørkøy; Ryan, Liv; Espevik, Terje; Boyartchuk, Victor. (2018) RORα controls inflammatory state of human macrophages. PLOS ONE
Academic article
Bösl, Korbinian; Giambelluca, Miriam; Haug, Markus; Bugge, Marit; Espevik, Terje; Kandasamy, Richard Kumaran. (2018) Coactivation of TLR2 and TLR8 in primary human monocytes triggers a distinct inflammatory signaling response. Frontiers in Physiology
Academic article
Stavik, Benedicte; Holm, Sverre; Espada Serrano, Sandra; Iversen, Nina; Sporsheim, Bjørnar; Bjerkeli, Vigdis. (2017) Increased expression of TFPI in human carotid stenosis. Thrombosis Research
Academic article
Espevik, Terje. (2017) Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation. Journal of Immunology
Academic article
Bakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Pilely, Katrine; Ryan, Liv; Skjelland, Mona. (2017) Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation. Journal of Immunology
Academic article
Ehrnstrøm, Birgitta; Beckwith, Kai Sandvold; Yurchenko, Mariya; Moen, Siv Helen; Kojen, June Frengen; Lentini, Germana. (2017) Toll-Like Receptor 8 Is a Major Sensor of Group B Streptococcus But Not Escherichia coli in Human Primary Monocytes and Macrophages. Frontiers in Immunology
Academic article
Lunde, Ngoc Nguyen Dieu; Holm, Sverre; Dahl, Tuva Børresdatter; Inass, Elyouncha; Sporsheim, Bjørnar; Gregersen, Ida. (2017) Increased levels of legumain in plasma and plaques from patients with carotid atherosclerosis. Atherosclerosis
Academic article
Bugge, Marit; Bergstrøm, Bjarte; Eide, Oda K.; Solli, Helene; Kjønstad, Ingrid Fadum; Stenvik, Jørgen. (2017) Surface Toll-Like Receptor 3 Expression in Metastatic Intestinal Epithelial Cells induces Selective Cytokine Production and Promotes Invasiveness. Journal of Biological Chemistry
Academic article
Espada Serrano, Sandra; Stavik, Benedicte; Holm, Sverre; Sagen, Ellen Lund; Bjerkeli, Vigdis; Skjelland, Mona. (2017) Tissue factor pathway inhibitor attenuates ER stress-induced inflammation in human M2-polarized macrophages. Biochemical and Biophysical Research Communications - BBRC
Academic article
Barratt-Due, Andreas; Pischke, Søren Erik; Nilsson, Per; Espevik, Terje; Mollnes, Tom Eirik. (2017) Dual inhibition of complement and Toll-like receptors as a novel approach to treat inflammatory diseases-C3 or C5 emerge together with CD14 as promising targets. Journal of Leukocyte Biology
Academic literature review
Niyonzima, Nathalie; Halvorsen, Bente; Sporsheim, Bjørnar; Garred, Peter; Aukrust, Pål; Mollnes, Tom Eirik. (2017) Complement activation by cholesterol crystals triggers a subsequent cytokine response. Molecular Immunology
Academic article
Gregersen, Ida; Sandanger, Øystein; Askevold, Erik Tandberg; Sagen, Ellen Lund; Yang, Kuan; Holm, Sverre. (2017) Interleukin 27 is increased in carotid atherosclerosis and promotes NLRP3 inflammasome activation. PLOS ONE
Academic article
Gravastrand, Caroline; Hamad, Shamal; Fure, Hilde; Steinkjer, Bjørg; Ryan, Liv; Oberholzer, José. (2017) Alginate microbeads are coagulation compatible, while alginate microcapsules activate coagulation secondary to complement or directly through FXII. Acta Biomaterialia
Academic article
Stavik, Benedicte; Espada, Sandra; Holm, Sverre; Bjerkeli, Vigdis; Sandset, Per Morten; Dahl, Tuva Børresdatter. (2017) TFPI in human atherosclerotic plaques. Research and Practice in Thrombosis and Haemostasis (RPTH)
Abstract
Hellerud, Bernt C; Orrem, Hilde Lang; Dybwik, Knut Gustav; Pischke, Søren Erik; Barratt-Due, Andreas; Castellheim, Albert. (2017) Combined inhibition of C5 and CD14 efficiently attenuated the inflammatory response in a porcine model of meningococcal sepsis. Journal of Intensive Care
Academic article
Varghese, Paramel G; Folkersen, Lasse; Strawbridge, Rona J.; Halvorsen, Bente; Yndestad, Arne; Ranheim, Trine. (2016) NLRP3 inflammasome expression and activation in human atherosclerosis. Journal of the American Heart Association (JAHA)
Academic article
Gustavsen, Alice; Nymo, Stig Haugset; Landsem, Anne; Christiansen, Dorte; Ryan, Liv; Husebye, Harald. (2016) Combined inhibition of complement and CD14 attenuates bacteria-induced inflammation in human whole blood more efficiently than antagonizing the toll-like receptor 4-MD2 complex. Journal of Infectious Diseases
Academic article
Ørning, Mathias Pontus; Hoem, Kine Samset; Coron, Abba Elizabeth; Skjåk-Bræk, Gudmund; Mollnes, Tom Eirik; Brekke, Ole Lars. (2016) Alginate microsphere compositions dictate different mechanisms of complement activation with consequences for cytokine release and leukocyte activation. Journal of Controlled Release
Academic article
Kleveland, Ola; Kunszt, Gabor; Bratlie, Marte; Ueland, Thor; Broch, Kaspar; Holte, Espen. (2016) Effect of a single dose of the interleukin-6 receptor antagonist tocilizumab on inflammation and troponin T release in patients with non-ST-elevation myocardial infarction: a double-blind, randomized, placebo-controlled phase 2 trial. European Heart Journal
Academic article
Niyonzima, Nathalie; Freeley, Simon; Arbore, Giuseppina; Le Friec, Gaelle; Lappegård, Knut Tore; Mollnes, Tom Eirik. (2016) The intracellular C5 system is critical to DAMP sensing and cellular responses in human monocytes. Immunobiology
Abstract
Zimmer, Sebastian; Grebe, Alena; Bakke, Siril Skaret; Bode, Niklas; Halvorsen, Bente; Ulas, Thomas. (2016) Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming. Science Translational Medicine
Academic article
Nymo, Stig Haugset; Gustavsen, Alice; Nilsson, Per; Lau, Corinna; Espevik, Terje; Mollnes, Tom Eirik. (2016) Human endothelial cell activation by Escherichia coli and staphylococcus aureus is mediated by TNF and IL-1β secondarily to activation of C5 and CD14 in whole blood. Journal of Immunology
Academic article
Pilely, Katrine; Rosbjerg, Anne; Genster, Ninette; Gál, Peter; Pál, Gábor; Halvorsen, Bente. (2016) Cholesterol crystals activate the lectin complement pathway via ficolin-2 and mannose-binding lectin: Implications for the progression of atherosclerosis. Journal of Immunology
Academic article
Malmo, Jostein; Moe, Nina; Krokstad, Sidsel; Ryan, Liv; Loevenich, Simon; Johnsen, Ingvild Bjellmo. (2016) Cytokine profiles in human metapneumovirus infected children: Identification of genes involved in the antiviral response and pathogenesis. PLOS ONE
Academic article
Espevik, Terje. (2015) Reconstituted High-Density Lipoprotein Attenuates Cholesterol Crystal-Induced Inflammatory Responses by Reducing Complement Activation. Journal of Immunology
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Hovland, Anders; Jonasson, Lena; Garred, Peter; Yndestad, Arne; Aukrust, Pål; Lappegård, Knut Tore. (2015) The complement system and toll-like receptors as integrated players in the pathophysiology of atherosclerosis. Atherosclerosis
Academic literature review
Egge, Kjetil Hagene; Barratt-Due, Andreas; Nymo, Stig Haugset; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Lau, Corinna. (2015) The anti-inflammatory effect of combined complement and CD14 inhibition is preserved during escalating bacterial load. Clinical and Experimental Immunology
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Nilsen, Nadra; Gregory I., Vladimer; Stenvik, Jørgen; Ørning, Mathias Pontus; Zeid-Kilani, Maria Vanessa; Bugge, Marit. (2015) A role for the adaptor proteins TRAM and TRIF in toll-like receptor 2 signaling. Journal of Biological Chemistry
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Lau, Corinna; Olstad, Ole Kristoffer; Holden, Marit; Nygård, Ståle; Fure, Hilde; Lappegård, Knut Tore. (2015) Gene expression profiling of Gram-negative bacteria-induced inflammation in human whole blood: The role of complement and CD14-mediated innate immune response. Genomics Data
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Sponaas, Anne-Marit; Moen, Siv Helen; Liabakk, Nina-Beate; Feyzi, Emadoldin; Holien, Toril; Kvam, Solveig. (2015) The proportion of CD16+CD14dim monocytes increases with tumor cell load in bone marrow of patients with multiple myeloma. Immunity,Inflammation and Disease
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Skjeflo, Espen Waage; Sagatun, Caroline; Dybwik, Knut; Aam, Sturla; Urving, Sven Haakon; Nunn, Miles A.. (2015) Combined inhibition of complement and CD14 improved outcome in porcine polymicrobial sepsis. Critical Care
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Bergstrøm, Bjarte; Aune, Marie Hjelmseth; Awuh, Jane Atesoh; Kojen, June Frengen; Blix, Kjetil Jordahl; Ryan, Liv. (2015) TLR8 senses Staphylococcus aureus RNA in human primary monocytes and macrophages and induces IFN-β production via a TAK1-IKKβ-IRF5 signaling pathway. Journal of Immunology
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Niyonzima, Nathalie; Samstad, Eivind; Aune, Marie Hjelmseth; Ryan, Liv; Bakke, Siril Skaret; Rokstad, Anne Mari. (2015) Reconstituted high-density lipoprotein attenuates cholesterol crystal-induced inflammatory responses by reducing complement activation. Journal of Immunology
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Klein, Dionne; Skjesol, Astrid; Kers-Rebel, Esther D.; Sherstova, Tatyana; Sporsheim, Bjørnar; Egeberg, Kjartan Wøllo. (2015) CD14, TLR4 and TRAM Show Different Trafficking Dynamics During LPS Stimulation. Traffic: The moving front of cell biology
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Lau, Corinna; Nygård, Ståle; Fure, Hilde; Olstad, Ole Kristoffer; Holden, Marit; Lappegård, Knut Tore. (2015) CD14 and complement crosstalk and largely mediate the transcriptional response to Escherichia coli in human whole blood as revealed by DNA microarray. PLOS ONE
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Lappegård, Knut Tore; Garred, Peter; Jonasson, Lena; Espevik, Terje; Aukrust, Pål; Yndestad, Arne. (2014) A vital role for complement in heart disease. Molecular Immunology
Academic literature review
Samstad, Eivind; Niyonzima, Nathalie; Nymo, Stig Haugset; Aune, Marie Hjelmseth; Ryan, Liv; Bakke, Siril Skaret. (2014) Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release. Journal of Immunology
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Østvik, Ann Elisabet; Granlund, Atle Van Beelen; Gustafsson, Björn; Torp, Sverre Helge; Espevik, Terje; Mollnes, Tom Eirik. (2014) Mucosal toll-like receptor 3-dependent synthesis of complement factor B and systemic complement activation in inflammatory bowel disease. Inflammatory Bowel Diseases
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Franklin, Bernardo S; Bossaller, Lukas; De Nardo, Dominic; Ratter, Jacqueline M; Stutz, Andrea; Engels, Gudrun. (2014) The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation. Nature Immunology
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Huber-Lang, Markus; Barratt-Due, Andreas; Pischke, Søren Erik; Sandanger, Øystein; Nilsson, Per; Nunn, Miles A.. (2014) Double blockade of CD14 and complement C5 abolishes the cytokine storm and improves morbidity and survival in polymicrobial sepsis in mice. Journal of Immunology
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Nymo, Stig Haugset; Niyonzima, Nathalie; Espevik, Terje; Mollnes, Tom Eirik. (2014) Cholesterol crystal-induced endothelial cell activation is complement-dependent and mediated by TNF. Immunobiology
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Skjeflo, Espen Waage; Christiansen, Dorte; Espevik, Terje; Nielsen, Erik Waage; Mollnes, Tom Eirik. (2014) Combined inhibition of complement and CD14 efficiently attenuated the inflammatory response induced by staphylococcus aureus in a human whole blood model. Journal of Immunology
Academic article
Nordgård, Catherine Taylor; Nonstad, Unni; Olderøy, Magnus Østgård; Espevik, Terje; Draget, Kurt Ingar. (2014) Alterations in mucus barrier function and matrix structure induced by guluronate oligomers. Biomacromolecules
Academic article
Arlov, Øystein; Aachmann, Finn Lillelund; Sundan, Anders; Espevik, Terje; Skjåk-Bræk, Gudmund. (2014) Heparin-Like Properties of Sulfated Alginates with Defined Sequences and Sulfation Degrees. Biomacromolecules
Academic article
Hetland, Geir; Tryggestad, Anne Merete Aaland; Espevik, Terje; Ryan, Liv. (2013) The medicinal mushroom Agaricus blazei Murill promotes NF-B activation via stimulation of TLR2 and inhibits its activation via TLR4. Journal of Pharmaceutical and Biomedical Sciences
Academic article
Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Strand, Berit Løkensgard. (2013) The induction of cytokines by polycation containing microspheres by a complement dependent mechanism. Biomaterials
Academic article
Østvik, Ann Elisabet; Granlund, Atle; Bugge, Marit; Nilsen, Nadra; Torp, Sverre Helge; Waldum, Helge. (2013) Enhanced expression of CXCL10 in inflammatory bowel disease: Potential role of mucosal toll-like 3 receptor stimulation. Inflammatory Bowel Diseases
Academic article
Lau, Corinna; Gunnarsen, Kristin Støen; Høydahl, Lene Støkken; Andersen, Jan Terje; Berntzen, Gøril; Pharo, Anne Margrethe. (2013) Chimeric Anti-CD14 IGG2/4 Hybrid Antibodies for Therapeutic Intervention in Pig and Human Models of Inflammation. Journal of Immunology
Academic article
Nymo, Stig Haugset; Samstad, Eivind; Niyonzima, Nathalie; Aune, Marie Hjelmseth; Bergseth, Grete; Ryan, Liv. (2013) Cholesterol crystals activate the complement system and are phagocytosed in a complement-dependent manner. Molecular Immunology
Abstract
Samstad, Eivind; Niyonzima, Nathalie; Nymo, Stig Haugset; Aune, Marie Hjelmseth; Ryan, Liv; Brekke, Ole Lars. (2013) Cholesterol crystals induce inflammasome activation and cytolcine release in a complement-dependent manner. Molecular Immunology
Abstract
Sandanger, Øystein; Ranheim, Trine; Vinge, Leif Erik; Bliksøen, Marte; Alfsnes, Katrine; Finsen, Alexandra. (2013) The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury. Cardiovascular Research (CVR)
Academic article
Grimstad, Øystein; Husebye, Harald; Espevik, Terje. (2013) TLR3 mediates release of IL-1 beta and cell death in keratinocytes in a caspase-4 dependent manner. Journal of dermatological science (Amsterdam)
Academic article
Østvik, Ann Elisabet; Granlund, Atle Van Beelen; Torp, Sverre Helge; Flatberg, Arnar; Beisvag, Vidar; Waldum, Helge. (2013) Expression of Toll-like receptor-3 is enhanced in active inflammatory bowel disease and mediates the excessive release of lipocalin 2. Clinical and Experimental Immunology
Academic article
Granlund, Atle Van Beelen; Flatberg, Arnar; Østvik, Ann Elisabet; Drozdov, Ignat; Gustafsson, Björn; Kidd, Mark. (2013) Whole Genome Gene Expression Meta-Analysis of Inflammatory Bowel Disease Colon Mucosa Demonstrates Lack of Major Differences between Crohn's Disease and Ulcerative Colitis. PLOS ONE
Academic article
Espevik, Terje. (2013) Sensorer som setter i gang betennelse: hvordan virker de og hvorfor trenger vi dem?. Årbok / Det norske videnskaps-akademi
Popular scientific article
Mollnes, Tom Eirik; Barratt-Due, Andreas; Pischke, Søren Erik; Sandanger, Inger; Nilsson, Per; Lambris, J. (2013) Double-blockade of CD14 and complement component C5 abolish the inflammatory storm and improve survival in mouse polymicrobial sepsis. Molecular Immunology
Abstract
Rokstad, Anne Mari; Strand, Berit Løkensgard; Espevik, Terje; Mollnes, Tom Eirik. (2013) Biocompatibility and Biotolerability Assessment of Microspheres Using a Whole Blood Model. Micro and Nanosystems
Academic article
Grimstad, Øystein; Pukstad, Brita; Stenvik, Jørgen; Espevik, Terje. (2012) Oligodeoxynucleotides inhibit Toll-like receptor 3 mediated cytotoxicity and CXCL8 release in keratinocytes. Experimental Dermatology
Academic article
Doyle, SL; Husebye, Harald; Connolly, D; Espevik, Terje; O'Neill, LAJ; McGettrick, AF. (2012) The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation. Nature Communications
Academic article
Rokstad, Anne Mari; Gustafsson, Björn; Espevik, Terje; Bakke, Ingunn; Pfragner, Roswitha; Svejda, Bernhard. (2012) Microencapsulation of small intestinal neuroendocrine neoplasm cells for tumor model studies. Cancer Science
Academic article
Stenvik, Jørgen; Sletta, Håvard; Grimstad, Øystein; Pukstad, Brita; Ryan, Liv; Aune, Randi. (2012) Alginates induce differentiation and expression of CXCR7 and CXCL12/SDF-1 in human keratinocytes - the role of calcium. Journal of Biomedical Materials Research. Part A
Academic article
Klein, Dionne; Øvrebø, Kirsti Marie; Latz, Eicke; Espevik, Terje; Stokke, Bjørn Torger. (2012) Direct measurement of the interaction force between immunostimulatory CpG-DNA and TLR9 fusion protein. Journal of Molecular Recognition
Academic article
Granlund, Atle; Flatberg, Arnar; Østvik, Ann Elisabet; Drozdov, I; Gustafsson, Björn; Kidd, M. (2012) Dissecting the IBD Transcriptome. Inflammatory Bowel Diseases
Abstract
Barratt-Due, Andreas; Pischke, Søren Erik; Brekke, Ole Lars; Thorgersen, Ebbe Billmann; Nielsen, Erik Waage; Espevik, Terje. (2012) Bride and groom in systemic inflammation - The bells ring for complement and Toll in cooperation. Immunobiology
Academic literature review
Østvik, Ann Elisabet; Nilsen, Nadra; Granlund, Atle; Torp, Sverre Helge; Flatberg, Arnar; Waldum, Helge. (2012) Enhanced expression of CXCL10 in inflammatory bowel disease-role of mucosal TLR3 stimulation. Journal of Crohn’s and Coltis Supplements
Abstract
Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Lambris, John D.. (2012) Poly-cation containing alginate microcapsules induce cytokines by a complement-dependent mechanism. Immunobiology
Abstract
Østvik, Ann Elisabet; Granlund, Atle Van Beelen; Torp, Sverre Helge; Flatberg, Arnar; Waldum, Helge; Espevik, Terje. (2012) Induction of Lipocalin-2 in Colonic Epithelial Cells in Inflammatory Bowel Disease. Inflammatory Bowel Diseases
Abstract
Christiansen, Dorte; Brekke, Ole Lars; Stenvik, Jørgen; Lambris, J.D.; Espevik, Terje; Mollnes, Tom Eirik. (2012) Differential Effect of Inhibiting MD-2 and CD14 on LPS- Versus Whole E. coli Bacteria-Induced Cytokine Responses in Human Blood. Advances in Experimental Medicine and Biology
Academic article
Nymo, Stig; Samstad, Eivind; Niyonzima, Nathalie; Bergseth, Grethe; Christiansen, Dorte; Ryan, Liv. (2012) Complement dependency of cholesterol crystal-induced inflammation - I. Pathway activation mechanisms, cytokine responses and endothelial cell activation. Immunobiology
Abstract
Christiansen, Dorte; Stenvik, Jørgen; Brekke, Ole Lars; Lambris, John D.; Espevik, Terje; Mollnes, Tom Eirik. (2012) Phagocytosis of Escherichia coli in human whole blood: Early complement dependency is succeeded by late CD14 dependency over time. Immunobiology
Abstract
Mollnes, Tom Eirik; Barratt-Due, Andreas; Pischke, Søren Erik; Sandanger, Øystein; Nunn, Miles A.; Espevik, Terje. (2012) The systemic inflammatory reaction in polymicrobial sepsis induced by murine cecal ligation and puncture is equally dependent on C5 and CD14. Immunobiology
Abstract
Niyonzima, Nathalie; Samstad, Eivind; Aune, Marie Hjelmseth; Ryan, Liv; Damås, Jan Kristian; Wright, Samuel. (2012) Complement dependency of cholesterol crystal-induced inflammation - II. Inflammasome activation and regulation mechanisms involving reconstituted high density lipoprotein (HDL) and C-reactive protein (CRP). Immunobiology
Abstract
Lau, Corinna; Gunnarsen, Kristin Støen; Høydahl, Lene Støkken; Berntzen, Gøril; Stokes, Christopher R.; Espevik, Terje. (2012) Recombinant anti-human and anti-porcine CD14 antibodies. Immunobiology
Abstract
Skjeflo, Espen; Christiansen, Dorte; Lambris, John D.; Espevik, Terje; Nielsen, Erik Waage; Mollnes, Tom Eirik. (2012) Combined inhibition of complement and CD14 efficiently attenuated the inflammatory response induced by Staphylococcus aureus in a human whole blood model. Immunobiology
Abstract
Torgersen, Maria Lyngaas; Engedal, Kim Nikolai; Pedersen, Anne-Mari Gjestvang; Husebye, Harald; Espevik, Terje; Sandvig, Kirsten. (2011) Toll-like receptor 4 facilitates binding of Shiga toxin to colon carcinoma and primary umbilical vein endothelial cells. FEMS Immunology and Medical Microbiology
Academic article
Grimstad, Øystein; Sandanger, Øystein; Ryan, Liv; Otterdal, Kari; Damås, Jan Kristian; Pukstad, Brita. (2011) Cellular sources and inducers of cytokines present in acute wound fluid. Wound Repair and Regeneration
Academic article
Nørgaard, Nikolai Nordberg; Holien, Toril; Jönsson, S; Hella, Hanne; Espevik, Terje; Sundan, Anders. (2011) CpG-ODN inhibits Smad-dependent BMP signaling; Effects on myeloma cell apoptosis and in vitro osteoblastogenesis. Bone
Abstract
Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Strand, Berit Løkensgard. (2011) Alginate microbeads are complement compatible, in contrast to polycation containing microcapsules, as revealed in a human whole blood model. Acta Biomaterialia
Academic article
Husebye, Harald; Aune, Marie Hjelmseth; Stenvik, Jørgen; Samstad, Eivind Ottersen; Skjeldal, Frode Miltzow; Halaas, Øyvind. (2010) The Rab11a GTPase Controls Toll-like Receptor 4-Induced Activation of Interferon Regulatory Factor-3 on Phagosomes. Immunity
Academic article
Salvesen, Bodil; Stenvik, Jørgen; Rosetti, Carlo; Saugstad, Ola D; Espevik, Terje; Mollnes, Tom E.. (2010) Meconium-induced release of cytokines is mediated by the TRL4/MD-2 complex in a CD14-dependent manner. Molecular Immunology
Academic article
Etokebe, GE; Skjeldal, F; Nilsen, Nadra; Rodionov, Dmitrii; Knezevic, Jelena; Bulat-Kardum, Ljiljana. (2010) Toll-Like Receptor 2 (P631H) Mutant Impairs Membrane Internalization and is a Dominant Negative Allele. Scandinavian Journal of Immunology
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Duewell, P; Kono, H; Rayner, KJ; Sirois, CM; Vladimer, G; Bauernfeind, FG. (2010) NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature
Academic article
Halaas, Øyvind; Steigedal, Magnus; Haug, Markus; Awuh, Jane Atesoh; Ryan, Liv; Brech, Andreas. (2010) Intracellular Mycobacterium avium Intersect Transferrin in the Rab11(+) Recycling Endocytic Pathway and Avoid Lipocalin 2 Trafficking to the Lysosomal Pathway. Journal of Infectious Diseases
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Nilsen, Asbjørn Magne; Vik, Randi; Behrens, Carl; Drabløs, Per Arne; Espevik, Terje. (2010) Beryllium Sensitivity Among Workers at a Norwegian Aluminum Smelter. American Journal of Industrial Medicine
Academic article
Nørgaard, Nikolai Nordberg; Holien, Toril; Jonsson, Sofia; Hella, Hanne; Espevik, Terje; Sundan, Anders. (2010) CpG-Oligodeoxynucleotide Inhibits Smad-Dependent Bone Morphogenetic Protein Signaling: Effects on Myeloma Cell Apoptosis and In Vitro Osteoblastogenesis. Journal of Immunology
Academic article
Klein, Dionne C.G.; Latz, Eicke; Espevik, Terje; Stokke, Bjørn Torger. (2010) Higher order structure of short immunostimulatory oligonucleotides studied by atomic force microscopy. Ultramicroscopy
Academic article
Pukstad, Brita; Ryan, Liv; Flo, Trude Helen; Stenvik, Jørgen; Moseley, Ryan; Harding, Keith. (2010) Non-healing is associated with persistent stimulation of the innate immune response in chronic venous leg ulcers. Journal of dermatological science (Amsterdam)
Academic article
Christiansen, D; Brekke, Ole Lars; Stenvik, Jørgen; Lambris, JD; Espevik, Terje; Mollnes, Tom Eirik. (2010) Differential effect of inhibiting MD-2 and CD14 on LPS- versus whole E. coli bacteria-induced cytokine responses in human blood. Molecular Immunology
Abstract
Hetland, Geir; Tryggestad, Anne Merete Aaland; Espevik, Terje; Ryan, Liv; Tangen, Jon-Magnus; Johnson, Egil. (2010) The Medicinal and Antitumor Mushroom, Agaricus Blazei Murill, Activates NF-kappa B Via TLR2 but Not TLR4 In Monocytic Cells, and Stimulates Monocyte-Derived Dendritic Cells (MDDC) to Increased Cell Surface Marker Expression and Cytokine Production, and May Thus Have Adjuvant Effect In MDDC Cancer Vaccines. Blood
Abstract
Hetland, Geir; Tryggestad, Anne Merete Aaland; Espevik, Terje; Ryan, Liv; Tangen, Jon-Magnus; Johnson, Egil. (2010) The medicinal and antitumour mushroom, agaricus blazei murill, activates NF-KB via TLR2 in monocytic cells and induces expression of cell surface markers and production of cytokines in human monocyte-derived dendritic cells (MDDC) in vitro. European Journal of Cancer
Abstract
Grimstad, Øystein; Pukstad, Brita; Stenvik, Jørgen; Espevik, Terje. (2010) TLR3 mediated cytotoxicity in keratinocytes is inhibited by co-stimulation with oligodeoxynucleotides. Journal of Investigative Dermatology
Abstract
Castellheim, A; Brekke, Ole Lars; Espevik, T; Harboe, M; Harboe, M; Mollnes, Tom Eirik. (2009) Innate Immune Responses to Danger Signals in Systemic Inflammatory Response Syndrome and Sepsis. Scandinavian Journal of Immunology
Academic literature review
Standal, Therese; Norgaard, NN; Bohnhorst, J; Espevik, T; Waage, A; Sundan, A. (2009) Does Toll-like Receptor 9 Signaling Play a Role in Myeloma Disease Progression?. Clinical Lymphoma & Myeloma
Abstract
Damås, Jan Kristian; Davi, Giovanni; Jensenius, M; Santilli, F; Otterdal, K; Ueland, T. (2009) Relative chemokine and adhesion molecule expression in Mediterranean spotted fever and African tick bite fever. Journal of Infection
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Yndestad, A; Landrø, Linn; Ueland, Thor; Dahl, CP; Flo, Trude Helen; Vinge, Leif Erik. (2009) Increased systemic and myocardial expression of neutrophil gelatinase-associated lipocalin in clinical and experimental heart failure. European Heart Journal
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Iversen, Ann-Charlotte; Steinkjer, Bjørg; Nilsen, Nadra; Bohnhorst, Janne Øvrebø; Moen, Siv Helen; Vik, Randi. (2009) A proviral role for CpG in cytomegalovirus infection. Journal of Immunology
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Palsson-McDermott, EM; Doyle, SL; McGettrick, AF; Hardy, M; Husebye, Harald; Banahan, K. (2009) TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway. Nature Immunology
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Sandanger, Øystein; Sandanger, O; Ryan, Liv; Bohnhorst, Janne Øvrebø; Iversen, Ann-Charlotte; Iversen, AC. (2009) IL-10 Enhances MD-2 and CD14 Expression in Monocytes and the Proteins Are Increased and Correlated in HIV-Infected Patients. Journal of Immunology
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Hetland, G; Tryggestad, AMA; Forland, T; Johnson, E; Ryan, L; Espevik, Terje. (2008) Proposed immunomodulatory co-therapy for hematological cancer by the medicinal mushroom Agaricus blazei Murill, is facilitated by its stimulation of TLR2 and activation of NF-KB. Vox Sanguinis
Abstract
Nilsen, Nadra; Deininger, S; Nonstad, Unni; Skjeldal, F; Husebye, Harald; Rodionov, D. (2008) Cellular trafficking of lipoteichoic acid and Toll-like receptor 2 in relation to signaling; role of CD14 and CD36. Journal of Leukocyte Biology
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Mollnes, Tom Eirik; Christiansen, D; Brekke, Ole Lars; Espevik, T. (2008) Hypothesis: Combined inhibition of complement and CD14 as treatment regimen to attenuate the inflammatory response. Advances in Experimental Medicine and Biology
Academic article
Hellerud, BC; Stenvik, Jørgen; Espevik, Terje; Lambris, John D.; Mollnes, Tom Eirik; Brandtzaeg, P. (2008) Stages of meningococcal sepsis stimulated in vitro, with emphasis on complement and Toll-like receptor activation. Infection and Immunity
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Hellerud, BC; Stenvik, Jørgen; Espevik, Terje; Lambris, JD; Mollnes, TE; Brandtzæg, Petter. (2008) Stages of meningococcal sepsis simulated in vitro, with emphasis on complement and Toll-like receptor activation. Infection and Immunity
Academic article
Landrø, Linn Aina Ysland; Landro, L; Damås, Jan Kristian; Damas, JK; Flo, Trude Helen; Heggelund, L. (2008) Decreased serum lipocalin-2 levels in human immunodeficiency virus-infected patients: increase during highly active anti-retroviral therapy. Clinical and Experimental Immunology
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Latz, E; Verma, Anjali; Visintin, A; Gong, Mei; Sirois, CM; Klein, Dionne. (2007) Corrigendum: Ligand-induced conformational changes allosterically activate Toll-like receptor 9. International Immunology
Academic article
Halaas, Øyvind; Husebye, Harald; Espevik, Terje. (2007) The journey of Toll-like receptors in the cell. Advances in Experimental Medicine and Biology
Academic article
Latz, Eicke; Verma, Anjali; Visintin, A; Gong, Mei; Sirois, Cherilyn m.; Klein, Dionne. (2007) Ligand-induced conformational changes allosterically activate Toll-like receptor 9. Nature Immunology
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Tunheim, G; Thompson, KM; Fredriksen, AB; Espevik, Terje; Schjetne, KW; Bogen, B. (2007) Human receptors of innate immunity (CD14, TLR2) are promising targets for novel recombinant immunoglobulin-based vaccine candidates. Vaccine
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Rokstad, Anne Mari Aukan; Donati, Ivan; Borgogna, Massimiliano; Oberholzer, José; Strand, Berit Løkensgard; Espevik, Terje. (2006) Cell-compatible covalently reinforced beads obtained from a chemoenzymatically engineered alginate. Biomaterials
Academic article
Husebye, Harald; Halaas, Øyvind; Stenmark, Harald; Tunheim, G; Sandanger, Øystein; Bogen, B. (2006) Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity. EMBO Journal
Academic article
Espevik, Terje; Lien, Egil. (2006) Vaksine mot svartedauen. Gemini
Popular scientific article
Espevik, Terje; Skjåk-Bræk, Gudmund. (2006) Friskere fisk med tang og tare. Gemini
Popular scientific article
Ueland, Thor; Espevik, Terje; Kjekshus, John; Gullestad, Lars; Omland, Torbjørn; Squire, Iain B.. (2006) Mannose binding lectin and soluble Toll-lilke receptor 2 in heart failure following acute myocardial infarction. Journal of Cardiac Failure
Academic article
Bohnhorst, Janne Øvrebø; Rasmussen, T; Moen, Siv H; Fløttum, Marianne; Knudsen, L; Børset, Magne. (2006) Toll-like receptors mediate proliferation and survival of multiple myeloma cells. Leukemia
Academic article
Johnsen, Ingvild Bjellmo; Nguyen, Thank Thuy Thi; Ringdal, Monika; Tryggestad, AM; Bakke, Oddmund; Lien, Egil. (2006) Toll-like receptor 3 associates with c-Src tyrosine kinase on endosomes to initiate antiviral signaling. EMBO Journal
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Mancuso, Guiseppe; Midiri, A; Biondo, Carmelo; Beninati, C.; Gambuzza, M; Macri, D. (2005) Bacteroides fragilis-derived lipopolysaccharide produces cell activation and lethal toxicity via toll-like receptor 4. Infection and Immunity
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Manukyan, M; Triantafilou, K; Triantafilou, M; Mackie, A; Nilsen, Nadra Jesmine; Espevik, Terje. (2005) Binding of lipopeptide to CD14 induces physical proximity of CD14, TLR2 and TLR1. European Journal of Immunology
Academic article
Heggelund, L; Mollnes, TE; Espevik, Terje; Muller, F; Kristiansen, KI; Aukrust, P. (2005) Modulatory effect of mannose-binding lectin on cytokine responses: roles in HIV infection. European Journal of Clinical Investigation
Academic article
Dybdahl, Brit; Slørdahl, Stig Arild; Waage, Anders; Kierulf, Peter; Espevik, Terje; Sundan, Anders. (2005) Myocardial ischaemia and the inflammatory response: release of heat shock protein 70 after myocardial infarction. Heart
Academic article
Heggelund, L; Mollnes, TE; Espevik, Terje; Muller, F; Kristiansen, KI; Aukrust, P. (2005) Modulatory effect of mannose-binding lectin on cytokine resposes: possible roles in HIV infection. European Journal of Clinical Investigation
Academic article
Heggelund, Lars; Mollnes, Tom Eirik; Espevik, Terje; Muller, Fredrik; Kristiansen, Knut Ivan; Aukrust, Pål. (2005) Modulatory effect of mannose-binding lectin on cytokine responses: possible roles in HIV infection. European Journal of Clinical Investigation
Academic article
Frantisek, S; Latz, E; Re, F; Mandell, L; Repik, G; Golenbock, D. (2004) Importance of extra-and intracellular domains of TLR1 and TLR2 receptors in NF-kappa B signaling. Tissue Antigens
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Heggelund, L; Flo, Trude Helen; Berg, K.; Lien, E; Espevik, Terje. (2004) Soluble toll-like receptor 2 in HIV infection: association with disease progression. AIDS (London)
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Halaas, Øyvind; Liabakk, Nina-Beate; Vik, Randi; Beninati, C; Henneke, P; Sundan, Anders. (2004) Monocytes stimulated with group B Streptococci or interferons release tumour necrosis factor-related apoptosis-inducing ligand. Scandinavian Journal of Immunology
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Nilsen, N; Nonstad, U; Khan, N; Knetter, Cathrine; Akira, S; Sundan, Anders. (2004) Lipopolysaccharide and double-stranded RNA up-regulate toll-like receptor 2 independently of myeloid differentiation factor 88. Journal of Biological Chemistry
Academic article
Dybdahl, Brit; Wahba, Alexander; Haaverstad, Rune; Kirkeby-Garstad, I.; Kierulf, P; Espevik, Terje. (2004) On-pump versus off-pump coronary artery bypass grafting: more heat-shock protein 70 is released after on-pump surgery. European Journal of Cardio-Thoracic Surgery
Academic article
Liabakk, Nina-Beate; Espevik, Terje. (2004) Monoclonal antibodies against TRAIL. Vitamines and Hormones
Academic article
Latz, E; Visintin, A; Espevik, Terje; Golenbock, DT. (2004) Mechanisms of TLR9 activation. Journal of Endotoxin Research
Academic article
Latz, E; Schoenemeyer, A; Visintin, A; Fitzgerald, KA; Monks, BG; Knetter, Cathrine. (2004) TLR9 signals after translocating from the ER to CpG DNA in the lysosome. Nature Immunology
Academic article
Heggelund, L; Muller, F; Lien, E; Yndestad, A; Ueland, T; Kristiansen, KI. (2004) Increased expression of Toll-like receptor 2 on monocytes in HIV infection: Possible roles in inflammation and viral replication. Clinical Infectious Diseases
Academic article
Espevik, Terje. (2004) Tolerance induced by the lipopeptide Pam3Cys is due to ablation of IL-1R-associated kinase-1. Journal of Immunology
Academic article
Heggelund, L; Damås, Jan Kristian; Damas, JK; Yndestad, A; Holm, AM; Muller, F. (2004) Stimulation of toll-like receptor 2 in mononuclear cells from HIV-infected patients induces chemokine responses: possible pathogenic consequences. Clinical and Experimental Immunology
Academic article
Dybdahl, Brit; Wahba, Alexander; Haaverstad, R; Kirkeby-Garstad, Idar; Kierulf, Peter; Espevik, Terje. (2004) On-pump versus off-pump coronary artery bypass grafting: more heat-shock protein 70 is released after on-pump surgery. European Journal of Cardio-Thoracic Surgery
Academic article
Heggelund, Lars; Flo, T; Berg, K; Lien, T; Mollnes, TE; Ueland, Thor. (2004) Soluble toll-like receptor 2 in HIV infection: association with disease progression. AIDS (London)
Academic article
Nilsen, Nadra; Nonstad, Unni; Kahn, Naseema; Knetter, Cathrine; Akira, Shizuo; Sundan, Anders. (2004) Lipopolysaccharide and Double-stranded RNA Up-regulate Toll-like Receptor 2 Independently of Myeloid Differentiation Factor 88. Journal of Biological Chemistry
Academic article
Latz, E; Visintin, A; Lien, E; Fitzgerald, KA; Espevik, Terje; Golenbock, DT. (2003) The LPS receptor generates inflammatory signals from the cell surface. Journal of Endotoxin Research
Academic article
Schjetne, KW; Thompson, Keith; Fleckenstein, Burkhard; Aarvak, Tanja; Flo, T. H.; Iversen, Jens Gustav. (2003) Cutting edge: Link between innate and adaptive immunity: toll like receptor 2 (TLR 2) captures antigen for MHC class II presentation to CD4+ T cell responses. Journal of Immunology
Academic article
Strand, Berit Løkensgard; Mørch, Yrr Asbjørg; Espevik, Terje; Skjåk-Bræk, Gudmund. (2003) Visualization of alginate-poly-L-lysine-alginate microcapsules by confocal laser scanning microscopy. Biotechnology and Bioengineering
Academic article
Strand, Berit Løkensgard; Mørch, Yrr Asbjørg; Syvertsen, Kjersti R.; Espevik, Terje; Skjåk-Bræk, Gudmund. (2003) Microcapsules made by enzymatically tailored alginate. Journal of Biomedical Materials Research
Academic article
Espevik, Terje; Latz, Eicke; Lien, Egil; Monks, Brian G.. (2003) Cell distribution and functions of Toll-like receptor 4 studied by fluorescent gene constructs. Scandinavian Journal of Infectious Diseases
Academic article
Mori, Y; Yoshimura, A; Ukai, T; Lien, Egil; Espevik, Terje; Hara, Y. (2003) Immunohistochemical localization of Toll-like receptors 2 and 4 in gingival tissue from patients with periodontitis. Oral Microbiology and Immunology
Academic article
Adib-Conquy, M; Moine, P; Asehnoune, K; Edouard, A; Espevik, Terje; Miyake, K. (2003) Toll-like receptor-mediated tumor necrosis factor and interleukin-10 production differ during systemic inflammation. American Journal of Respiratory and Critical Care Medicine
Academic article
Visintin, A; Latz, Eicke; Monks, Brian G.; Espevik, Terje; Golenbock, Douglas T.. (2003) Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction. Journal of Biological Chemistry
Academic article
Schjetne, KW; Thompson, KM; Nilsen, Nadra; Flo, Trude Helen; Fleckenstein, B; Iversen, JG. (2003) Cutting edge: link between innate and adaptive immunity: Toll-like receptor 2 internalizes antigen for presentation to CD4+ T cells and could be an efficient vaccine target. Journal of Immunology
Academic article
Sandor, F; Latz, Eicke; Mandell, L; Repik, G; Golenbock, Douglas T.; Espevik, Terje. (2003) Importance of extra- and intracellular domains of TLR1 and TLR2 in NFkappa B signaling. Journal of Cell Biology
Academic article
Rokstad, Anne Mari Aukan; Strand, Berit Løkensgard; Rian, K.; Steinkjer, Bjørg; Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund. (2003) Evaluation of different types of alginate microcapsules as bioreactors for producing endostatin. Cell Transplantation
Academic article
Espevik, Terje. (2002) På väg att knäcka hjärntumörer. Länstidningen, Østersund, Sverige
Feature article
Dybdahl, Brit; Lien, Egil; Flo, Trude Helen; Espevik, Terje; Sundan, Anders; Wahba, Alexander. (2002) Heat Shock Proteins and Endotoxin Combined as a Trigger for Inflammatory Cytokine Release During Cardiopulmonary Bypass: A Possible Third Way? Letter til artikkel. Circulation
Academic article
Rokstad, Anne Mari Aukan; Holtan, Synnøve; Strand, Berit Løkensgard; Steinkjer, Bjørg; Ryan, Liv; Kulseng, Bård Eirik. (2002) Microencapsulation of cells producing therapeutic proteins: Optimizing cell growth and secretion. Cell Transplantation
Academic article
Flo, Trude Helen; Ryan, Liv; Latz, Eicke; Takeuchi, Osamu; Monks, Brian G.; Lien, Egil. (2002) Involvement of toll-like receptor (TLR) 2 and TLR4 in cell activation by mannuronic acid polymers. Journal of Biological Chemistry
Academic article
Tamai, Riyoko; Sakuta, T; Matsushita, K; Torii, M; Takeuchi, Osamu; Akira, Shizuo. (2002) Human gingival CD14(+) fibroblasts primed with gamma interferon increase production of interleukin-8 in response to lipopolysaccharide through up-regulation of membrane CD14 and MyD88 mRNA expression. Infection and Immunity
Academic article
Latz, Eicke; Visintin, A; Lien, Egil; Fitzgerald, KA; Monks, Brian G.; Kurt-Jones, EA. (2002) Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the Toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction. Journal of Biological Chemistry
Academic article
van der Kleij, D; Latz, Eicke; Brouwers, JF; Kruize, YC; Schmitz, M; Kurt-Jones, EA. (2002) A novel host-parasite lipid cross-talk. Schistosomal lyso-phosphatidylserine activates Toll-like recepytor 2 and affects immune polarization. Journal of Biological Chemistry
Academic article
Liabakk, Nina-Beate; Sundan, Anders; Torp, Sverre Helge; Aukrust, Pål; Frøland, Stig Sophus; Espevik, Terje. (2002) Development, characterization and use of monoclonal antibodies against sTRAIL measurement of sTRAIL by ELISA. Journal of Immunological Methods (JIM)
Academic article
Belge, KU; Dayyani, F; Horelt, A; Siedlar, M; Frankenberger, M; Frankenberger, B. (2002) The proinflammatory CD14+CD16+DR++ monocytes are a major source of TNF. Journal of Immunology
Academic article
Dybdahl, Brit; Wahba, Alexander; Lien, Egil; Flo, Trude Helen; Waage, Anders; Sellevold, Olav F Münter. (2002) Inflammatory response after open heart surgery: release of heat-shock protein 70 and signaling through toll-like receptor-4. Circulation
Academic article
Ellingsen, E.A.; Morath, S; Flo, Trude Helen; Schromm, Andra; Hartung, T; Thiemermann, C. (2002) Induction of cytokine production in human T cells and monocytes by highly purified lipoteichoic acid: involvement of Toll-like receptors and CD14. Medical Science Monitor
Academic article
Strand, Berit Løkensgard; Gåserød, Olav; Kulseng, Bård Eirik; Espevik, Terje; Skjåk-Bræk, Gudmund. (2002) Alginate-polylysine-alginate microcapsules – effect of size reduction on capsule properties. Journal of Microencapsulation
Academic article
Lien, Egil; Chow, Jesse C.; Hawkins, Lynn D.; McGuinness, Pamela D.; Miyake, Kensuke; Espevik, Terje. (2001) A novel synthetic acyclic lipid A-like agonist activates cells via the lipopolysaccharide/Toll-like receptor 4 signaling pathway. Journal of Biological Chemistry
Academic article
Liabakk, Nina-Beate; Waage, Anders; Lien, Egil; Stenvik, Jørgen; Espevik, Terje. (2001) Cytokine bioassays. Methods in Molecular Medicine
Academic article
Strand, Berit Løkensgard; Ryan, Liv; Int Veld, Peter; Kulseng, Bård Eirik; Rokstad, Anne Mari Aukan; Skjåk-Bræk, Gudmund. (2001) Poly-L-Lysine Induces Fibrosis on Alginate Microcapsules via the Induction of Cytokines. Cell Transplantation
Academic article
Flo, Trude Helen; Ryan, Liv; Kilaas, L; Skjåk-Bræk, Gudmund; Ingalls, Robin; Sundan, Anders. (2001) The involvement of CD14 and beta2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers. Infection and Immunity
Academic article
Wang, J; Warris, A; Ellingsen, E.A.; Jorgensen, P.F.; Flo, Trude Helen; Espevik, Terje. (2001) Involvement of CD14 and toll-like receptors in activation of human monocytes by Aspergillus fumigatus hyphae. Infection and Immunity
Academic article
Liabakk, Nina-Beate; Sundan, Anders; Torp, Sverre Helge; Aukrust, Pål; Frøland, Stig; Espevik, Terje. (2001) Development, characterization and use of monclonal antibodies against Strail: Measurement of Strail by Elisa. Journal of Immunological Methods (JIM)
Academic article
Henneke, Philipp; Takeuchi, Osamu; van Strijp, JA; Guttormsen, HK; Smith, JA; Schromm, Andra. (2001) Novel engagement of CD14 and multiple toll-like receptors by group B streptococci. Journal of Immunology
Academic article
Flo, Trude Helen; Halaas, Øyvind; Torp, Sverre Helge; Ryan, Liv; Lien, Egil; Dybdahl, Brit. (2001) Differential expression of Toll-like receptor 2 in human cells. Journal of Leukocyte Biology
Academic article
Sugawara, Shunji; Yang, Shuhua; Iki, Koichi; Hatakeyama, Junko; Tamai, Riyoko; Takeuchi, Osamu. (2001) Monocytic cell activation by nonendotoxic glycoprotein from Prevotella intermedia ATCC 25611 is mediated by Toll-like receptor 2. Infection and Immunity
Academic article
Rokstad, Anne Mari Aukan; Kulseng, Bård Eirik; Strand, Berit Løkensgard; Skjåk-Bræk, Gudmund; Espevik, Terje. (2001) Transplantation of alginate microcapsules with proliferating cells in mice. Capsular overgrowth and suvival of encapsulated cells of mice and human origin. Annals of the New York Academy of Sciences
Academic article
Iversen, Ann-Charlotte; Sundan, Anders; Espevik, Terje. (2001) IFN-alpha(2b) and IFN-beta induce TRAIL-mediated NK cell cytotoxicity. The FASEB Journal
Abstract
Skjåk-Bræk, Gudmund; Flo, Trude Helen; Halaas, Øyvind; Espevik, Terje. (2000) Immune stimulating properties of di-equatorially beta(1->4) linked poly-uronides. Proceedings of the Phytochemical Society of Europe
Academic article
Flo, Trude Helen; Halaas, Øyvind; Lien, Egil; Ryan, Liv; Teti, Guiseppe; Golenbock, Douglas T.. (2000) Human Toll-like Receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide. Journal of Immunology
Academic article
Cuzzola, Maria; Mancuso, Guiseppe; Beninati, Concetta; Biondo, Carmelo; von Hunolstein, Christina; Orefici, Graziella. (2000) Human monocyte receptors involved in tumor necrosis factor responses to group B streptococcal products. Infection and Immunity
Academic article
Cuzzola, M.; Mancuso, G.; Beninati, C.; Biondo, C.; Genovese, F.; Tomasello, F.. (2000) _B2 integrins are involved in cytokine responses to whole gram-positive bacteria. Journal of Immunology
Academic article
Flo, Trude Helen; Ryan, Liv; Kilaas, Lars; Skjåk-Bræk, Gudmund; Ingalls, Robin R.A; Sundan, Anders. (2000) Involvement of CD14 and _B2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers. Infection and Immunity
Academic article
Falch, Berit H.; Espevik, Terje; Ryan, Liv; Stokke, Bjørn Torger. (2000) The cytokine stimulating activity of (1->3)-_B-D-glucans is dependent on the triple helix conformation. Carbohydrate Research
Academic article
Flo, T.H.; Ryan, L.; Kilaas, L.; Skjåk-Bræk, Gudmund; Ingalls, R.R.; Sundan, A.. (2000) Involvement of CD14 and beta2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers. Infection and Immunity
Academic article
Lien, E.; Espevik, Terje. (2000) Toll-lignende reseptorer - kroppens sensorer for infeksjon. NBS-nytt
Popular scientific article
Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund; Ryan, Liv; Andersson, Arne; King, Aileen; Faxvaag, Arild. (1999) Transplantation of alginate microcapsules. Generation of antibodies against alginates and encapsulated porcine islet-like cell clusters. Transplantation
Academic article
Kulseng, Bård Eirik; Vatten, Lars Johan; Espevik, Terje. (1999) Soluble tumor necrosis factor receptors in sera from patients with insulin-dependent diabetes mellitus: relations to duration and complications of disease. Acta Dermato-Venereologica
Academic article
Kulseng, Bård Eirik; Espevik, Terje; Skjåk-Bræk, Gudmund. (1999) Behandling av diabetes mellitus med transplantasjon av immunbeskyttet øyvev fra pancreas. Tidsskrift for Den norske legeforening (Tidsskriftet)
Academic article
Børset, Magne; Hjort-Hansen, Henrik; Johnsen, Ann-Charlotte; Seidel, Carina; Waage, Anders; Espevik, Terje. (1999) Apoptosis, proliferation and NF-k(kappa)B activation induced by agonistic Fas antibodies in the human myeloma cell line OH-2: amplification of Fas-mediated apoptosis by tumor necrosis factor. European Journal of Haematology
Academic article
Aukrust, Pål; Müller, Fredrik; Lien, Egil; Nordøy, Ingvild; Liabakk, Nina-Beate; Kvale, Dag. (1999) Tumor necrosis factor (TNF) system levels in human immunodificiency virus-infected patients during highly active antiretroviral therapy: Perisistent TNF activation is associated with virologic and immunologic treatment failure. Journal of Infectious Diseases
Academic article
Heine, Holger; Delude, Russell L.; Monks, Biran G.; Espevik, Terje; Golenbock, Douglas T.. (1999) Bacterial lipopolysaccharide induces expression of the stress response genes Hop and H411. Journal of Biological Chemistry
Academic article
Aukrust, Pål; Haug, Charlotte J.; Ueland, Thor; Lien, Egil; Muller, Fredrik; Espevik, T. (1999) Decreased bone formative and enhanced resorptive markers in human immunodeficiency virus infection: indication of normalization of the bone-remodeling process during highly active antiretroviral therapy. Journal of Clinical Endocrinology and Metabolism (JCEM)
Academic article
Aukrust, Pål; Ueland, Thor; Lien, Egil; Bendtzen, Klaus; Muller, Fredrik; Andreassen, Arne K.. (1999) Cytokine network in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. American Journal of Cardiology
Academic article
Aukrust, Pål; Muller, Fredrik; Lien, Egil; Nordøy, Ingvild; Liabakk, Nina-Beate; Kvale, Dag. (1999) Tumor necrosis factor (TNF) system in human immunodeficiency virus-infected patients during highly active antiretroviral therapy (HAART): Persistent TNF activation is associated with virologic and immunologic treatment failure. Journal of Infectious Diseases
Academic article
Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund; Ryan, Liv; Andersson, Arne; King, Aileen; Faxvaag, Arild. (1999) Transplantation of alginate microcapsules. Transplantation
Academic article
Johnsen, Ann-Charlotte; Haux, Johan; Steinkjer, Bjørg; Nonstad, Unni; Egeberg, Kjartan Wøllo; Sundan, Anders. (1999) Regulation of APO-2 ligand /Trail expression in NK cells - involvement in NK cell-mediated cytotoxicity. Cytokine
Academic article
Lien, Egil; Sellati, Timothy J.; Yoshimura, Atsutosi; Flo, Trude Helen; Rawadi, Georges; Finberg, Robert W.. (1999) Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products. Journal of Biological Chemistry
Academic article
Aukrust, Pål; Haug, Charlotte J.; Ueland, Thor; Lien, Egil; Müller, Fredrik; Espevik, Terje. (1999) Decreased bone formative and enhanced resorptive markers in human immunodeficiency virus infection: Indication of normalization of the bone-remodeling process during highly active antiretroviral therapy. Journal of Clinical Endocrinology and Metabolism (JCEM)
Academic article
Haux, Johan; Iversen, Ann-Charlotte; Johnsen, Ann-Charlotte; Steinkjer, Bjørg; Egeberg, Kjartan Wøllo; Sundan, Anders. (1999) The role of IL-2 in regulating the sensitivity of NK cells for Fas-mediated apoptosis. Cancer Immunology and Immunotherapy
Academic article
Gullestad, Lars; Aukrust, Pål; Ueland, Thor; Espevik, T; Yee, G.; Vagelos, R.. (1999) Effect of high- versus low-dose angiotensin converting enzyme inhibition on cytokine levels in chronic heart failure. Journal of the American College of Cardiology
Academic article
Iversen, Ann-Charlotte; Johnsen, Ann-Charlotte; Haux, Johan; Steinkjer, Bjørg; Nonstad, Unni; Egeberg, Kjartan Wøllo. (1999) Regulation of Apo-2 Ligand/Trail expression in NK cells - Involvement in NK cell mediated cytotoxicity. Cytokine
Academic article
Lien, E; Nonstad, Unni; Sundan, A; Espevik, Terje. (1999) Polymorphonuchlear of Fas and Fas-Ligand expression in NK cells by cytokines and the involved of Fas-Ligand in NK/LAK cell-mediated cytotoxicity. Cytokine
Academic article
Johnsen, A-C; Steinkjer, B; Egeberg, Kathrine; Sundan, A; Espevik, Terje. (1999) The role of international-2 in regulation the sensitivity of natural killer celler for Fas-mediated apoptosis. European Journal of Haematology
Academic article
Iversen, Ann-Charlotte; Johnsen, Ann-Charlotte; Haux, Johan; Steinkjer, Bjørg; Nonstad, Unni; Egeberg, Kjartan Wøllo. (1998) Regulation of Apo-2 Ligand/TRAIL expression in NK cells - Involvement in NK cell mediated cytotoxicity. Journal of Interferon and Cytokine Research
Abstract
Thommesen, Liv; Sjursen, Wenche; Gåsvik, Kathrine; Hanssen, Wenche; Brekke, Ole-Lars; Skattebøl, Lars. (1998) Selective inhibitors of cytosolic or secretory phospholipase A2 block TNF-induced activation of transcription factor nuclear factor-kappa B and expression of ICAM-1. Journal of Immunology
Academic article
Kulseng, Bård Eirik; Espevik, Terje; Sundan, A. (1998) Elevated hepatocyte growth factor in sera from patients with insulin-dependent diabetes mellitus. Acta Dermato-Venereologica
Academic article
Lien, E; Sundan, A; Aukrust, P; Frøland, S; Espevik, Terje. (1998) Elevated levels of serum-soluble CD14 in human immunodeficiency virus type 1 (HIV-1) infection: correlation to disease progression and clinical events. Blood
Academic article
Berntzen, G.; Flo, T; Medvedev, A; Kilaas, L; Skjåk-Bræk, Gudmund; Sundan, A. (1998) The tumor necrosis factor-inducing potency of lipopolysaccharide and uronic acid polymers is increased when they are covalently linked to particles. Clinical and Vaccine Immunology
Academic article
Halaas, Øyvind; Vik, R; Espevik, Terje. (1998) Induction of Fas ligand in murine bone marrow NK cells by bacterial polysaccharides. Immunology
Academic article
Ingalls, RR; Monks, BG; Savedra R, [Mangler fornavn]; Christ, WJ; Delude, RL; Medvedev, AE. (1998) CD11/CD18 and CD14 share a common lipid A signaling pathway. Journal of Immunology
Academic article
Medvedev, AE; Flo, T; Vogel, SN; Robin, R; Golenbock, DT; Teti, G. (1998) Involvement of CD14 and complement receptors CR3 and CR4 in nuclear factor-kappaB activation and TNF production induced by lipopolysaccharide and group B streptococcal cell walls. Journal of Immunology
Academic article
Lien, Egil; Aukrust, Pål; Sundan, Andreas; Muller, Fredrik; Frøland, Stig Sophus; Espevik, T. (1998) Elevated levels of serum-soluble CD14 in human immonudeficiency virus type 1 (HIV-1) infection: correlation to disease progression and clinical events. Blood
Academic article
Jahr, Tove Gullstein; Ryan, Liv; Sundan, Anders; Lichenstein, Henri S.; Skjåk-Bræk, Gudmund; Espevik, Terje. (1997) Induction of tumor necrosis factor production from monocytes stimulated with mannuronic acid polymers and involvement of lipopolysaccharide-binding protein, CD14, and bactericidal/ permeability-increasing factor. Infection and Immunity
Academic article
Aukrust, Pål; Hestad, Kjetil; Lien, Egil; Bjerkeli, Vigdis; Nordøy, Ingvild; Espevik, T. (1997) Effects of intravenous immunoglobulin in vivo on abnormally increased tumor necrosis factor-_a activity in human immunodeficiency virus type 1 infection. Journal of Infectious Diseases
Academic article
Hestad, Kjetil; Aukrust, Pål; Muller, Fredrik; Lien, Egil; Bjerkeli, Vigdis; Espevik, T. (1997) Dysregulation of membrane-bound tumor necrosis factor-_a and tumor necrosis factor receptors on mononuclear cells in human immunodeficiency virus type 1 infection: Low percentage of p75-tumor necrosis factor receptor positive cells in patients with advanced disease and high viral load. Blood
Academic article
Hestdal, Kjetil; Aukrust, Pål; Müller, Fredrik; Lien, Egil; Bjerkeli, Vigdis; Espevik, Terje. (1997) Dysregulation of membrane-bound tumor necrosis factor-_a and tumor necrosis factor receptors on mononuclear cells in human immunodeficiency virus type 1 infection : low percentage of p75-tumor necrosis factor receptor positive cells in patients with advanced disease and high viral load. Blood
Academic article
Sandler, Stellan; Andersson, Arne; Eizirik, Décio L.; Hellerström, Claes; Espevik, Terje; Kulseng, Siri. (1997) Assessment of insulin secretion in vitro from microencapsulated fetal procine islet-like cell clusters and rat, mouse, and human pancreatic islets. Transplantation
Academic article
Aukrust, Pål; Hestdal, Ketil; Lien, Egil; Bjerkeli, Vigdis; Nordøy, Ingvild; Espevik, Terje. (1997) Effects of intravenous immunoglobulin in vivo on abnormally increased tumor necrosis factor-alpha activity in human immunodeficiency virus type 1 infection. Journal of Infectious Diseases
Academic article
Kulseng, Bård Eirik; Thu, Beate; Espevik, Terje; Skjåk-Bræk, Gudmund. (1997) Alginate polylysine microcapsules as immune barrer : permeability of cytokines and immmunoglobulins over the capsule membrane. Cell Transplantation
Academic article
Jackson, A.M.; Lien, Egil; Alexandroff, A.B.; Espevik, Terje; James, K.; Selby, P.J.. (1997) Soluble urinary CD14 after intravesical bacille Calmette-Guérin immunotherapy for carcinoma in situ. British Journal of Urology
Academic article
Medvedev, Andrei E.; Iversen, Ann-Charlotte; Johnsen, Ann-Charlotte; Haux, Johan; Steinkjer, Bjørg; Egeberg, Kjartan Wøllo. (1997) Regulation of Fas and Fas-Ligand expression in NK cells by cytokines and the involvement of Fas-Ligand in NK/LAK cell-mediated cytotoxicity. Cytokine
Academic article
Børset, Magne; Medvedev, Andrei E.; Sundan, Anders; Espevik, Terje. (1996) The role of the two TNF receptors in proliferation, NF-_KB activation and discrimination between TNF and LT_a signalling in the human myeloma cell line OH-2. Cytokine
Academic article
Børset, Magne; Lien, Egil; Espevik, Terje; Helseth, Eirik; Waage, Anders; Sundan, Anders. (1996) Concomitant expression of hepatocyte growth factor/scatter factor and the receptor c-MET in human myeloma cell lines. Journal of Biological Chemistry
Academic article
Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund; Følling, Ivar; Espevik, Terje. (1996) TNF production from peripheral blood mononuclear cells in diabetic patients after stimulation with alginate and lipopolysaccharide. Scandinavian Journal of Immunology
Academic article
Thu, Beate; Bruheim, Per; Espevik, Terje; Smidsrød, Olav; Soon-Shiong, P.; Skjåk-Bræk, Gudmund. (1996) Alginate polycation microcapsules. I, Interaction between alginate and polycation. Biomaterials
Academic article
Medvedev, Andrei E.; Espevik, Terje; Ranges, Gerald; Sundan, Anders. (1996) Distinct roles of the two tumor necrosis factor (TNF) receptors in modulating TNF and lymphotoxin _a effects. Journal of Biological Chemistry
Academic article
Medvedev, Andrei E.; Lægreid, Astrid; Sundan, Anders; Espevik, Terje. (1996) A non-competitive P55 TNF receptor antibody enhances the specific activity of Lymphotoxin-_a. Scandinavian Journal of Immunology
Academic article
Haug, Charlotte J.; Aukrust, Pål; Lien, Egil; Müller, Fredrik; Espevik, Terje; Frøland, Stig S.. (1996) Disseminated Mycobacterium avium complex infection in AIDS : immunopathogenic significance of an activated tumor necrosis factor system and depressed serum levels of 1,25 dihydroxyvitamin D. Journal of Infectious Diseases
Academic article
Skjåk-Bræk, Gudmund; Espevik, Terje. (1996) Application of alginate gels in biotechnology and biomedicine. Carbohydrates in Europe
Academic article
Thu, Beate; Bruheim, Per; Espevik, Terje; Smidsrød, Olav; Soon-Shiong, Patrick; Skjåk-Bræk, Gudmund. (1996) Alginate polycation microcapsules. II, Some functional properties. Biomaterials
Academic article
Aukrust, Pål; Lien, Egil; Kristoffersen, Anne K.; Müller, Fredrik; Haug, Charlotte J.; Espevik, Terje. (1996) Persistent activation of the tumor necrosis factor system in a subgroup of patients with common variable immunodeficiency : possible immunologic and clinical consequences. Blood
Academic article
Aukrust, Pål; Lien, Egil; Kristoffersen, Anne Karin; Muller, Fredrik; Haug, Charlotte J.; Espevik, T. (1996) Persistant Activation of The Tumor Nevcrosis Factor System in a Subgroup of Patients With Common Varable Immunodeficincy - Possible Immunological and Clinical and Consequences. Blood
Academic article
Haug, Charlotte J.; Aukrust, Pål; Lien, Egil; Muller, Fredrik; Espevik, T; Frøland, Stig Sophus. (1996) Disseminated Mycobacterium avium complex (MAC) infection in AIDS: Immunopathogenic significance of an activated tumor necrosis factor (TNF) system and depressed serum levels of 1,25-dihydroxyvitamin D. Journal of Infectious Diseases
Academic article
Aukrust, Pål; Lien, Egil; Kristoffersen, Anne Karin; Muller, Fredrik; Haug, Charlotte J.; Espevik, T. (1996) Persistent activation of tumor necrosis factor system in a subgroup of patients with common variable immunodeficiency - Possible immunologic and clinical concensus. Blood
Academic article
Skjermo, Jorunn; Defoort, Thomas; Dehasque, Marleen; Espevik, Terje; Olsen, Yngvar; Skjåk-Bræk, Gudmund. (1995) Immunostimulation of juvenile turbot (Scophthalmus maximus L.) using an alginate with high mannuronic acid content administered via the live food organism Artemia. Fish and Shellfish Immunology
Academic article
Samuelsen, Anne Berit; Paulsen, Berit Smestad; Wold, Jens Krisitian; Otsuka, Hanako; Yamada, Haruki; Espevik, T. (1995) Isolation and partial characterization of biologically active polysaccharides from Plantago major L. Phytotherapy Research
Academic article
Arntzen, KJ; Liabakk, N-B; Jacobsen, G.; Espevik, Terje; Austgulen, Rigmor. (1995) Soluble tumor necrosis factor receptor in serum and urine througout normal pregnancy and delivery. American Journal of Reproductive Immunology
Academic article
Lien, Egil; Liabakk, Nina-Beate; Iversen, Ann-Charlotte; Johnsen, Ann-Charlotte; Nonstad, Unni; Sundan, Anders. (1995) Polymorphonuclear granulocytes enhance lipopolysaccharide-induced p75 tumor necrosis factor receptor release from mononuclear cells. European Journal of Immunology
Academic article
Waage, A.; Halstensen, Alfred; Espevik, T.; Brandtzæg, P.. (1994) Cytokines in meningococcal disease. Baillière's Clinical Infectious Diseases
Academic article
Halgunset, J; Johnsen, H; Kjøllesdal, AM; Qvigstad, E; Espevik, Terje; Austgulen, Rigmor. (1994) Normal parturition at term is associated with subtle inflammatory reactions in-utero. European Journal of Obstetrics, Gynecology, and Reproductive Biology
Academic article
Brekke, OL; Espevik, Terje; Bjerve, Kristian S. (1994) Butylated Hydroxyanisole Inhibits Tumor Necrosis Factor induced Cytotoxicity and Arachidonic Acid Release. Lipids
Academic article
Austgulen, Rigmor; Liabakk, N-B; Richardsen, W; Rahimipoor, S; Vatn, I; Espevik, Terje. (1993) Serum levels of soluble TNF receptors are influenced by gestational age and delivery in normal pregnancy. Placenta
Abstract
Waage, A.; Halstensen, Alfred; Espevik, T.; Brandtzæg, P.. (1993) Compartmentalization of the TNF and IL-6 in meningitis and septic shock. Mediators of Inflammation
Academic article
Austgulen, Rigmor; Liabakk, N-B; Lien, E; Espevik, Terje. (1993) Increased levels of soluble TNF-alpha receptors in serum from pregnant women, and in serum and urine samples from newborns. Pediatric Research
Academic article
Liabakk, N-B; Lien, E; Sundan, A; Sunde, A; Austgulen, Rigmor; Espevik, Terje. (1993) High concentrations of the soluble p55 tumor necrosis factor receptor in human seminal plasma. Human Reproduction
Academic article
Austgulen, Rigmor; Kjøllesdal, AM; Johnsen, H; Liabakk, N-B; Espevik, Terje. (1993) Soluble receptors for tumor necrosis factor: occurence in association with normal delivery at term. Obstetrics and Gynecology
Academic article
Naume, Bjørn; Iversen, Ann-Charlotte; Johnsen, Ann-Charlotte; Espevik, Terje; Sundan, Anders. (1993) Gene expression and secretion of cytokines and cytokine receptors from hihgly purified CD56+ natural killer cells stimulated with interleukin-2, interleukin-7 and interleukin-12. European Journal of Immunology
Academic article
Austgulen, Rigmor; Naume, B; Johnson, A-C; Espevik, Terje; Sundan, A. (1993) Gene expression and secretion of cytokines and cytokines from highly purified CD56* natural killer cells stimulated with interleukin-2, interleukin-7 and interleukin-12. European Journal of Immunology
Academic article
Soon-Shong, P.; Feldman, E.; Nelson, R.; Komtebedde, J.; Smidsrød, Olav; Skjåk-Bræk, Gudmund. (1992) Successful reversal of spontaneous diabetes in dogs by intraperitonal microencapsulated islets. Transplantation
Academic article
Brandtzæg, P.; Halstensen, Alfred; Kierulf, P.; Espevik, T.; Waage, A.. (1992) Molecular mechanisms in the compartmentalized inflammatory response presenting as meningococcal meningitis or septic shock. Microbial Pathogenesis
Academic article
Austgulen, Rigmor; Espevik, Terje; Mecsei, R; Scott, H. (1992) Expression of receptors for tumor necrosis factor in human placenta at term. Acta Obstetricia et Gynecologica Scandinavica
Academic article
Austgulen, Rigmor; Liabakk, N-B; Espevik, Terje. (1992) Sekresjon av løselige reseptorer for tumor nekrose faktor - en immunologisk buffermekanisme under svangerskap?. Tidsskrift for Den norske legeforening (Tidsskriftet)
Academic article
Austgulen, Rigmor; Liabakk, NB; Brockhaus, M; Espevik, Terje. (1992) Soluble TNF receptors in amniotic fluid and in urine from pregnant women. Journal of Reproductive Immunology
Academic article
Brekke, OL; Espevik, Terje; Bardal, Tora; Bjerve, Kristian S. (1992) Effects of n-3 and n-6 fatty acids on Tumor Necrosis Factor cytotoxicity in WEHI fibrosarcoma cells. Lipids
Academic article
Brekke, OL; Shalaby, MR; Sundan, Anders; Espevik, Terje; Bjerve, Kristian S. (1992) Butylated hydroxyanisol specifically inhibits Tumor Necrosis Factor induced cytotoxicity and growth enhancement. Cytokine
Academic article
Austgulen, Rigmor; Liabakk, N-B; Scott, H; Brockhaus, M; Espevik, Terje. (1991) Soluble TNF receptors in urine and in amniotic fluid from pregnant women. Placenta
Abstract
Waage, A.; Brandtzæg, P.; Espevik, T.; Halstensen, Alfred. (1991) Current understanding of the pathogenesis of gram negative shock. Infectious Disease Clinics of North America
Academic article
Nissen-Meyer, J; Austgulen, Rigmor; Espevik, Terje. (1988) Synergistic growth inhibitory activity of tumor necrosis factor and interferon-alpha: contribution to the monocyte-derived cytostatic activity towards human leukemia K562 cells. Scandinavian Journal of Immunology
Academic article
Nissen-Meyer, J; Hofsli, E; Espevik, Terje; Austgulen, Rigmor. (1988) Involvement of tumor necrosis factor in cytotoxicity mediated by human monocytes. Natural immunity and cell growth regulation
Academic article
Austgulen, Rigmor; Espevik, Terje; Nissen-Meyer, J. (1987) Fibroblast growth stimulatory activity from human monocytes: The contribution of tumor necrosis factor. Scandinavian Journal of Immunology
Academic article
Nissen-Meyer, J; Austgulen, Rigmor; Espevik, Terje. (1987) Comparison of recombinant tumor necrosis factor and the monocyte-derived cytotoxic factor (CF) which is involved in the monocyte-mediated cytotoxicity. Cancer Research
Academic article
Austgulen, Rigmor; Espevik, Terje; Degree, M. (1987) Monocyte-derived influence on growth of normal human fibroblasts: The contribution of tumor necrosis factor to growth inhibition. Scandinavian Journal of Immunology
Academic article
Bjerve, Kristian S; Espevik, Terje; Kildahl-Andersen, O; Nissen-Meyer, J. (1987) Effect of free fatty acids on the cytolytic activity of tumor necrosis factor/¬monocyte-derived cytotoxic factor. APMIS - Journal of Pathologiy, Microbiology and Immunology
Academic article
Austgulen, Rigmor; Kildahl-Andersen, O; Espevik, Terje. (1986) Monocyte-mediated drug-dependent cellular cytotoxicity: Effects of different WEHI 164 target cell lines. Cancer Immunology and Immunotherapy
Academic article
Austgulen, Rigmor; Espevik, Terje; Hammerstrøm, J; Nissen-Meyer, J. (1986) Role of monocyte cytotoxic factor in cytolysis of actinomycin D treated WEHI 164 cells mediated by freshly isolated human adherent mononuclear blood cells. Cancer Research
Academic article
Austgulen, Rigmor; Hammerstrøm , J; Espevik, Terje; Nissen-Meyer, J. (1986) Human monocyte cytotoxic factor mediates cytolysis of WEHI 164 cells. Cellular Immunology
Academic article

Books

Klein, Dionne C.G.; Latz, Eicke; Espevik, Terje; Stokke, Bjørn Torger. (2008) Effects of CpG-DNA on Toll-like receptor 9 studied by AFM. TRAUNER Verlag TRAUNER Verlag
Academic anthology/Conference proceedings
Rokstad, Anne Mari Aukan; Bjerkvig, Rolf; Espevik, Terje; Lund-Johansen, M. (2005) Applications of Cell Immobilisation Biotechnology, Focus on Biotechnology. Book chapter: Cell encapsulation therapy for malignant gliomas. Springer Springer
Academic anthology/Conference proceedings
Espevik, Terje; Waage, Anders; Sundan, A.. (2000) Summary of the 8 th International TNF Congress. Trondheim. NBS-nytt
Non-fiction book

Part of book/report

Espevik, Terje; Rokstad, Anne Mari; Kulseng, Bård Eirik; Strand, Berit Løkensgard; Skjåk-Bræk, Gudmund. (2009) Mechanisms of the host immune response to alginate microcapsules.
Chapter
Halaas, Øyvind; Husebye, Harald; Stenmark, Harald; Espevik, Terje. (2008) Intracellular Trafficing of Toll-like Receptors. CRC Press
Academic chapter/article/Conference paper
Waage, A.; Halstensen, Alfred; Brandtzæg, P.; Espevik, T.. (1992) TNF in serum in patients with bacterial infections.
Academic chapter/article/Conference paper

Report

Bösl, Korbinian; Kandasamy, Richard Kumaran; Espevik, Terje. (2019) Novel insights on human–virus interactions through genome–wide approaches. Norwegian University of Science and Technology
Doctoral dissertation
Nejati Moharrami, Neda; Boyartchuk, Victor; Espevik, Terje. (2018) Role of CD5L in control of human innate immune function. Doktoravhandlinger ved NTNU (395)
Doctoral dissertation
Sherstova, Tatyana; Stokke, Bjørn Torger; Anthonsen, Marit Walbye; Espevik, Terje. (2016) Quantitative atomic force microscopy and light microscopy of hydrogels and cells. Norwegian University of Science and Technology
Doctoral dissertation
Bugge, Marit; Nilsen, Nadra J.; Espevik, Terje. (2016) Toll-Like Receptor 3 Signaling in Intestinal Epithelial Cells. Norwegian University of Science and Technology
Doctoral dissertation
Nilsen, Nadra; Espevik, Terje; Lien, Egil. (2008) Toll-like receptor 2 expression, regulation and signaling. Tapir Akademisk Forlag Tapir Akademisk Forlag
Doctoral dissertation
Nilsen, Asbjørn Magne; Vik, Randi; Espevik, Terje. (2006) BeLPT testing Karmøy. Undervegsrapport 1. Januar 2006. Norges Teknisk-Naturvitenskapelige Universitet
Report
Nilsen, Asbjørn Magne; Vik, Randi; Espevik, Terje. (2006) Be-LPT testing at Hydro Aluminium Karmøy AS. Final Report. June 2006. Norwegian University of Science and Technology
Report
Nilsen, Asbjørn Magne; Vik, Randi; Espevik, Terje. (2006) Be-LPT testing Karmøy. Undervegsrapport 4. April 2006. Norges Teknisk-Naturvitenskapelige Universitet
Report
Nilsen, Asbjørn Magne; Vik, Randi; Espevik, Terje. (2006) Be-LPT testing Karmøy. Undervegsrapport 3. Mars 2006. Norges Teknisk-Naturvitenskapelige Universitet
Report
Nilsen, Asbjørn Magne; Vik, Randi; Espevik, Terje. (2006) Be-LPT testing Karmøy. Undervegsrapport 2. Februar 2006. Norges Teknisk-Naturvitenskapelige Universitet
Report
Jenssen, Jon A; Espevik, Terje. (2001) Cellebiologisk metode for å påvise biologisk aktivitet av svevestøv. SINTEF Rapport
Report
Espevik, Terje; Waage, Anders; Sundan, Anders. (2000) Summary of the 8th International TNF Congress, Trondheim, May 14-18, 2000. NBS-nytt
Report
Skjåk-Bræk, Gudmund; Espevik, Terje; Otterlei, Marit; Smidsrød, Olav; Soon-Shiong, P.. (1995) Homologous guluronic acid alginate coating composition for in vivo application and implantation and method using the same. US-Patent 5459 054, Oct. 1995
Report

Information material

Espevik, Terje. (2013) CEMIR sitt forskningstema er inflammasjon.
Website (informational material)
Espevik, Terje. (2013) CEMIR's research topic is inflammation.
Website (informational material)

Outreach

2024

Academic lecture

Cimpan, Mihaela Roxana; Rios-Mondragon, Ivan; Camassa, Laura Maria Azzurra; Puntes, Victor Franco; Gajewicz Skrętna, Agnieszka; Busquets, Marti. (2024) Towards a reliable assessment of nanomaterial health effects using advanced biological models and assays (NanoBioReal). H2020 DIAGONAL, HARMLESS, and SUNSHINE projects NANOTOX 2024 , Venice 2024-09-23 - 2024-09-25
Poster

Nilsen, Kaja Elisabeth; Skjesol, Astrid; Bakke, Siril Skaret; Ryan, Liv; Stenvik, Jørgen; Espevik, Terje. (2024) SLAMF1-derived peptide inhibits signaling initiated by endosomal Toll-like receptors. TOLL 2024 , Rotterdam 2024-04-17 - 2024-04-20
Poster

Mestvedt, Ingvild Bergdal; Yurchenko, Maria; Espevik, Terje; Standal, Therese; Wolowczyk, Camilla Izabel; Rasheed, Kashif. (2024) Exploring peptide derived from Signaling Lymphocytic Activation Molecule Family 1 as novel treatment for multiple myeloma. EORTC NCI and AACR (ENA) ENA 2024 Symposium on molecular targets and cancer therapeutics , Barcelona 2024-10-23 - 2024-10-25
Poster

Gravastrand, Caroline Saugestad; Yurchenko, Maria; Kristensen, Stine; Skjesol, Astrid; Espevik, Terje; Husebye, Harald. (2024) The Rab11-family interacting protein 2 is a key regulator of the NLRP3 inflammasome . Douglas Golenbock, UMASS, USA Poster , Rotterdam 2024-04-17 - 2024-04-20
Poster

Gravastrand, Caroline Saugestad; Yurchenko, Maria; Kristensen, Stine; Skjesol, A.; Espevik, Terje; Husebye, Harald. (2024) The Rab GTPase Rab11b and its effector Rab11-FIP2 are key regulators of the NLRP3 inflammasome . EMBO Cell death: Friend or foe in animal and plant immunity , San Feliu de Guixols 2024-10-11 - 2024-10-15

2023

Academic lecture

Nilsen, Asbjørn Magne; Espevik, Terje. (2023) Human whole blood: Model for toxicity assessment?. Institutt for klinisk odontologi, Universitetet i Bergen Workshop on: New Approach Methodologies for NanoSafety. NanoBioReal, NFR project 288768 , Bergen 2023-03-30 - 2023-03-31
Poster

Nilsen, Kaja Elisabeth; Zhang, Boyao; Skjesol, Astrid; Bakke, Siril Skaret; Gravastrand, Caroline Saugestad; Ryan, Liv. (2023) SLAMF1-derived peptide could limit the inflammation mediated by several Toll-like receptors. 18th International Conference on Innate Immunity , Chania 2023-05-31 - 2023-06-05
Poster

Mestvedt, Ingvild Bergdal; Yurchenko, Maria; Misund, Kristine; Hella, Hanne; Espevik, Terje; Slørdahl, Tobias Schmidt. (2023) SLAMF1-derived peptide P7N4-Pen as anti-myeloma treatment. International Myeloma Society 20th International Myeloma Society Annual Meeting , Athens 2023-09-27 - 2023-09-30

2022

Academic lecture

Espevik, Terje. (2022) The double-edged sword of inflammation . Norsk Biokjemis Selskap Kontaktmøte 2022-02-10 - 2022-02-13
Academic lecture

Espevik, Terje. (2022) Activation of the complement system by cholesterol crystals . 14th International Conference on Complement Therapeutics 2022-06-17 - 2022-06-22
Academic lecture

Husebye, Harald; Gravastrand, Caroline Saugestad; Yurchenko, Mariya; Skjesol, Astrid; Espevik, Terje. (2022) The Rab11-family interacting protein 2 is a regulator of the NLRP3 inflammasome . School of Education, University of Iceland BNMI – Bridging the Nordic Microscopy Infrastructure , Reykjavik 2022-08-17 - 2022-08-19
Academic lecture

Espevik, Terje. (2022) Inflammatory responses of cholesterol crystals in atherosclerotic disease . Drug discovery targeting inflammation 2022-11-17 - 2022-11-18
Academic lecture

Espevik, Terje. (2022) Inflammatory potential of cholesterol crystals in aortic disease – role of complement . 3rd International Symposium on Aortic Disease 2022-03-22 - 2022-03-25
Academic lecture

Espevik, Terje. (2022) Fedme og Inflammasjon. Fedmekunnskap: Status og framtid 2022-06-10 - 2022-06-10
Lecture

Brekke, Ole Lars; Grond, Joost; Landsem, Anne; Christiansen, Dorte; Ludviksen, Judith K; Lau, Corinna. (2022) Effects of complement C3, C5 and CD14 inhibitors on bacterial survival and thromboinflammation induced by two different live E.coli-strains in human whole blood . Aegean Conferences Complement Therapeutics 2022 , Sheraton Rhodos Hotell 2022-06-17 - 2022-06-22
Poster

Husebye, Harald; Gravastrand, Caroline Saugestad; Yurchenko, Mariya; Espevik, Terje. (2022) The Rab11-family interacting protein 2 is a regulator of the NLRP3 inflammasome . EMBO EMBO Workshop Dying in self-defense: Cell death signaling in animals and plants , Kreta 2022-05-01 - 2022-05-05

2021

Academic lecture

Espevik, Terje. (2021) Role of the Complement system in Inflammasome Activation mediated by Cholesterol Crystals . Keystone Symposia 2021-04-03 - 2021-04-06

2020

Academic lecture

Narverud, Ingunn; Christensen, Jacob Juel; Bakke, Siril Skaret; Ulven, Stine Marie; Rundblad, Amanda; Aukrust, Pål. (2020) Profiling of immune‐related gene expression in children with familial hypercholesterolaemia. Department of Nutrition Throne-Holst Stiftelse Festaften , Department of Nutrition/Zoom 2020-10-15 - 2020-10-15

2019

Poster

Skjesol, Astrid; Yurchenko, Mariya; Bösl, Korbinian; Gravastrand, Caroline S.; Nilsen, Kaja Elisabeth; Agliano, Federica. (2019) The TLR4 adaptor TRAM controls phagocytosis of E. coli through FIP2 . CEMIR, NTNU 2nd Conference on Molecular Mechanisms of Inflammation , Trondheim 2019-06-03 - 2019-06-06
Poster

Gravastrand, Caroline S.; Skjesol, Astrid; Yurchenko, Mariya; Jakovljev, Aleksandra; Afset, Jan Egil; Espevik, Terje. (2019) FIP2 regulates inflammatory cell death in human macrophages. EMBO EMBL symposia Seeing is Believing - Imaging the Molecular Processes of Life , EMBL Heidelberg 2019-10-09 - 2019-10-12
Poster

Gravastrand, Caroline S.; Steinkjer, Bjørg; Halvorsen, Bente; Landsem, Anne; Skjelland, Mona; Jacobsen, Eva Astrid. (2019) Cholesterol crystals induce thromboinflammation. CEMIR Conference on molecular mechanisms in Trondheim , Trondheim 2019-06-03 - 2019-06-06
Academic lecture

Espevik, Terje. (2019) Cholesterol crystals use complement to increase NLRP3 signalling pathways in atherosclerosis. Aegean Conferences 12th International Conference on Complement Therapeutics , Rhodes, Greece 2019-06-12 - 2019-06-17
Poster

Ehrnstrøm, Birgitta; Kojen, June Frengen; Moen, Siv Helen; Damås, Jan Kristian; Mollnes, Tom Eirik; Hu, Zhenyi. (2019) Toll-like receptor 8 senses bacteria in human whole blood. CEMIR, NTNU International conference on molecular mechanisms of inflammation , Trondheim 2019-06-03 - 2019-06-06
Poster

Stenvik, Jørgen; Ehrnstrøm, Birgitta; Kojen, June Frengen; Moen, Siv Helen; Beckwith, Kai Sandvold; Giambelluca, Miriam. (2019) TLR8 is a central bacterial sensor in human monocytes. CEMIR, NTNU International Conference on Molecular Mechanisms of Inflammation , Trondheim 2019-06-03 - 2019-06-06
Lecture

Espevik, Terje. (2019) Phagocytosis and phagocytic signaling for antibacterial defence. Gøteborg University, Sahlgrenska universityhospital Invited lecture at Gøteborg University , Gøteborg University, Sahlgrenska universityhospital 2019-04-27 - 2019-04-27
Poster

Moen, Siv Helen; Kojen, June Frengen; Yurchenko, Mariya; Ehrnstrøm, Birgitta; Damås, Jan Kristian; Espevik, Terje. (2019) Cell surface TLRs antagonize TLR8 signaling in monocytes via an IRAK-1 dependent mechanism. CEMIR, NTNU International conference of molecular mechanisms of inflammation , Trondheim 2019-06-03 - 2019-06-06
Interview

Flo, Trude Helen; Espevik, Terje. (2019) Betennelse – et tveegget sverd for helse og sykdom. Adresseavisa Adresseavisa [Newspaper] 2019-06-05
Poster

Gravastrand, Caroline S.; Skjesol, Astrid; Yurchenko, Mariya; Jakovljev, Aleksandra; Afset, Jan Egil; Espevik, Terje. (2019) FIP2 regulates inflammatory cell death in macrophages. EMBO EMBO workshop, Cell death in immunity and inflammation , Kreta 2019-10-06 - 2019-10-09

2018

Poster

Christensen, Jacob J.; Bakke, Siril Skaret; Ulven, Stine Marie; Retterstøl, Kjetil; Henriksen, Tore; Bollerslev, Jens. (2018) Association between omega 6 fatty acids and inflammation-related gene expression in PBMCs: a cross-sectional study in healthy children. Scandinavian society of atherosclerosis Research Scandinavian society of atherosclerosis Research , Humlebæk 2018-04-11 - 2018-04-14
Poster

Stavik, Benedicte; Tinholt, Mari; Skjelland, Mona; Espevik, Terje; Sandset, Per Morten; Halvorsen, Bente. (2018) Coagulation factors in human atherosclerotic plaques – a potential link to inflammation?. European Society of Cardiology Working Group Thrombosis Eurothrombosis 2018 , Barcelona 2018-10-04 - 2018-10-06
Poster

Bösl, Korbinian; Giambelluca, Miriam; Haug, Markus; Bugge, Marit; Espevik, Terje; Kandasamy, Richard Kumaran. (2018) Coactivation of TLR2 and TLR8 in Primary Human Monocytes Triggers a Distinct Inflammatory Signaling Response. Research School in Infection Biology and and Antimicrobials Annual Meeting Research School in Infection Biology and and Antimicrobials , Tromsø 2018-10-29 - 2018-10-30
Poster

Moen, Siv Helen; Kojen, June Frengen; Ehrnstrøm, Birgitta; Damås, Jan Kristian; Espevik, Terje; Stenvik, Jørgen. (2018) CROSSTALK OF HUMAN TLR2 AND TLR8 SIGNALING. 2nd. International NTNU Symposium on Current and Future Clinical Biomarkers of Cancer , Trondheim 2018-06-14 - 2018-06-15
Poster

Moen, Siv Helen; Kojen, June Frengen; Ehrnstrøm, Birgitta; Damås, Jan Kristian; Espevik, Terje; Stenvik, Jørgen. (2018) CROSSTALK OF HUMAN TLR2 AND TLR8 SIGNALING. Toll 2018 Editing Innate Immunity , Porto 2018-06-06 - 2018-06-09
Academic lecture

Rokstad, Anne Mari; Gravastrand, Caroline S.; Halvorsen, Bente; Steinkjer, Bjørg; Skjelland, Mona; Jacobsen, Eva Astrid. (2018) Cholesterol crystals induce coagulation that can be prevented by targeting complement. Agean Conferences 11th International Conference on Complement Therapeutics , Crete 2018-06-23 - 2018-06-25
Poster

Skjesol, Astrid; Yurchenko, Mariya; Espevik, Terje; Husebye, Harald. (2018) The TLR4 adaptor TRAM controls phagocytosis of Gram-negative bacteria through TRAM and the Rab11-family interacting protein 2 . Toll 2018, Editing Innate Immunity , Porto 2018-06-06 - 2018-06-09
Academic lecture

Espevik, Terje. (2018) Phagocytosis of Gram-negative bacteria requires the Toll-like receptor 4 adapter TRAM. 15th International Conference on Innate Immunity 2018-06-18 - 2018-06-23
Academic lecture

Espevik, Terje. (2018) Phagocytic signalling for antibacterial defence. Toll2018 Editing Innate Immunity 2018-06-06 - 2018-06-09
Poster

Ehrnström, Birgitta; Kojen, June Frengen; Moen, Siv Helen; Damås, Jan Kristian; Afset, Jan Egil; Mollnes, Tom Eirik. (2018) Toll-like Receptor 8 is a Major Bacterial Sensor in Human Monocytes and Blood. Toll 2018 2018-06-06 - 2018-06-09
Poster

Yurchenko, Mariya; Skjesol, Astrid; Husebye, Harald; Espevik, Terje. (2018) SLAMF1 regulates signaling via TLR4 and bacterial killing in human macrophages. Toll 2018. Editing Innate Immunity , Porto 2018-06-06 - 2018-06-09
Academic lecture

Espevik, Terje. (2018) Microcapsules Biocompatibility. 10th Microencapsulation Training School 2018-10-18 - 2018-10-21
Poster

Lunde, Ngoc Nguyen Dieu; Holm, Sverre; Dahl, Tuva Børresdatter; Elyouncha, Inass; Sporsheim, Bjørnar; Gregersen, Ida. (2018) Plasma and plaques from patients with carotid atherosclerosis have increased levels of legumain . The Scandinavian Society for Atherosclerosis Research (SSAR) 24th Annual Scandinavian Atherosclerosis Conference , Humlebæk 2018-04-11 - 2018-04-14
Poster

Lunde, Ngoc Nguyen Dieu; Gregersen, Ida; Holm, Sverre; Michelsen, Annika; Sporsheim, Bjørnar; Espevik, Terje. (2018) Platelet-derived legumain, a cysteine protease involved in atherosclerosis . Gordon Research Conference Proteolytic Enzymes and Their Inhibitors Gordon Research Conference , Lucca 2018-06-03 - 2018-06-08
Poster

Bugge, Marit; EIde, Oda Kamilla; Solli, Helene; Kjønstad, Ingrid Fadum; Stenvik, Jørgen; Bergstrøm, Bjarte. (2018) SURFACE TOLL-LIKE RECEPTOR 3 EXPRESSION IN METASTATIC INTESTINAL EPITHELIAL CELLS INDUCES INFLAMMATORY CYTOKINE PRODUCTION AND PROMOTES INVASIVENESS. UMASS Medical School and University of Freiburg Toll 2018 Translating Innate Immunity , Porto 2018-06-06 - 2018-06-09
Academic lecture

Bugge, Marit; Espevik, Terje; Nilsen, Nadra. (2018) Altered Toll-Like Receptor Expression and Signaling in Colorectal Cancer Cells promotes Invasiveness. NTNU/St. Olav’s Hospital 2nd International NTNU Symposium Current and Future Clinical Biomarkers of Cancer: From diagnosis to immunotherapy – why is precision medicine so difficult? , Trondheim 2018-06-14 - 2018-06-15

2017

Poster

Skjesol, Astrid; Sporsheim, Bjørnar; Yurchenko, Mariya; Egeberg, Kjartan Wøllo; Espevik, Terje; Husebye, Harald. (2017) The TLR4 adaptor TRAM controls phagocytosis of Gram-negative bacteria . 17th International European Light Microscopy Initiative Meeting , Dubrovnik 2017-05-23 - 2017-05-26
Lecture

Niyonzima, Nathalie; Freeley, Simon; Arbore, Giuseppina; Le Friec, Gaelle; Lappegaard, Knut Tore; Mollnes, Tom Eirik. (2017) The intracellular C5 system is critical to DAMP sensing and cellular responses in human monocytes. Lecture 2017-09-09 - 2017-09-12
Lecture

Espevik, Terje; Niyonzima, Nathalie; Bakke, Siril Skaret; Halvorsen, Bente; Gregersen, Ida; Skjelland, Mona. (2017) Systemic- and local complement activation controls the NLRP3 inflammasome pathway in patients with atherosclerosis. Lecture 2017-09-09 - 2017-09-12
Poster

Bugge, Marit; Bergstrøm, Bjarte Aune; Eide, Oda K.; Solli, Helene; Kjønstad, Ingrid Fadum; Stenvik, Jørgen. (2017) Surface Toll-Like Receptor 3 Expression in Metastatic Intestinal Epithelial Cells induces Inflammatory Cytokine Production and Promotes Invasiveness. Universitats Klinikum Freiburg Development of Tissue- and Pathogen-specific Cellular Innate Immunity , Freiburg 2017-09-27 - 2017-09-29
Poster

Skjesol, Astrid; Yurchenko, Mariya; Espevik, Terje; Husebye, Harald. (2017) The TLR4 adaptor TRAM controls phagocytosis of Gram-negative bacteria through interaction with the Rab11-family interacting protein 2. Keystone Symposia on Molecular and Cellular Biology Type I Interferon: Friend and Foe Alike (X6) , Banff 2017-03-19 - 2017-03-23
Academic lecture

Husebye, Harald; Skjesol, Astrid; Yurchenko, Mariya; Grøvdal, Lene Melsæther; Bösl, Korbinian; Agliano, Federica. (2017) The TLR4 adaptor TRAM controls phagocytosis of Gram-negative bacteria through the Rab11-family interacting protein 2. CEMIR Cemir retreat , Taormina, Sicily 2017-10-16 - 2017-10-19
Poster

Skjesol, Astrid; Husebye, Harald; Yurchenko, Mariya; Egeberg, Kjartan Wøllo; Espevik, Terje. (2017) The TLR4 adaptor TRAM controls phagocytosis of Gram-negative bacteria . Seeing is Believing , Heidelberg 2017-10-04 - 2017-10-07
Poster

Lunde, Ngoc Nguyen Dieu; Holm, Sverre; Dahl, Tuva B.; Elyoncha, Inass; Sporsheim, Bjørnar; Gregersen, Ida. (2017) Plasma and plaques from patients with carotid atherosclerosis have increased levels of legumain. International Proteolysis Society (IPS) 10th General Meeting of the International Proteolysis Society (IPS) , Banff 2017-10-28 - 2017-11-01
Poster

Bakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Pilely, Katrine; Ryan, Liv; Skjelland, Mona. (2017) Cyclodextrin inhibits CC-induced complement activation. the 16th European Meeting on Complement in Human Disease 2017-09-08 - 2017-09-12

2016

Poster

Skjesol, Astrid; Yurchenko, Mariya; Agliano, Federica; Patane, Francesco; Teti, Guiseppe; McCaffrey, Mary. (2016) Rab11-family interacting protein 2 mediates phagocytosis of E.coli. CEMIR, NTNU Conference on Molecular Mechanisms of Inflammation 2016-05-30 - 2016-06-02
Poster

Gravastrand, Caroline; Steinkjer, Bjørg; Fure, Hilde; Niyonzima, Nathalie; Lambris, John D.; Mollnes, Tom Eirik. (2016) Cholesterol crystals induce coagulation activation in a complement-dependent manner. Aegean Conferences 2nd International Conference on Immune Responses to Biosurfaces: Mechanisms and Therapeutic Interventions , Rhodos 2016-09-29 - 2016-10-01
Lecture

Yurchenko, Mariya; Skjesol, Astrid; Husebye, Harald; Espevik, Terje. (2016) CD150 positively regulates TRAM recruitment to E.coli phagosomes and type I IFN secretion. Cell symposium - 100 years of phagocytes , Giardini Naxos, Sicily 2016-09-19 - 2016-09-22
Poster

Yurchenko, Mariya; Skjesol, Astrid; Husebye, Harald; Espevik, Terje. (2016) CD150 positively regulates TRAM recruitment to E. coli phagosomes and TLR4-induced IFNbeta production. CEMIR Conference on Molecular Mechanisms of Inflammation , Trondheim 2016-05-30 - 2016-06-02
Poster

Stavik, Benedicte; Espada, Sandra; Holm, Sverre; Bjerkeli, Vigdis; Sandset, Per Morten; Dahl, Tuva Børresdatter. (2016) Cholesterol crystals induce TFPI expression in alternatively activated human monocyte-derived macrophages. Centre of Molecular Inflammation Research (CEMIR) Conference on Molecular Mechanisms of Inflammation , Trondheim (Norway) 2016-05-30 - 2016-06-02
Academic lecture

Stenvik, Jørgen; Bergstrøm, Bjarte; Aune, Marie Hjelmseth; Awuh, Jane Atesoh; Kojen, June Frengen; Blix, Kjetil Jordahl. (2016) TLR8 Senses Staphylococcus aureus RNA in Human Primary Monocytes and Macrophages and Induces IFN-b Production via a TAK1–IKKb–IRF5 Signaling Pathway. CEMIR NTNU International Conference on Molecular Mechanisms of Inflammation , Trondheim 2016-05-30 - 2016-06-02
Poster

Christiansen, Dorte; Skjeflo, Espen Waage; Landsem, Anne; Dammen Mathisen, Monica; Fure, Hilde; Stenvik, Jørgen. (2016) The effect of combined inhibition of C5aR1 and CD14 on phagocytosis of E. coli in human whole blood. The XXVI International Complement Workshop (ICW) , Kanazawa 2016-09-04 - 2016-09-08
Poster

Skjesol, Astrid; Yurchenko, Mariya; Agliano, Federica; Patane, Francesco; Teti, Guiseppe; McCaffrey, Mary. (2016) Rab11-family interacting protein 2 (FIP2) mediates phagocytosis of E.coli. Elsevier Conferences Cell symposium - 100 years of phagocytes 2016-09-19 - 2016-09-22
Poster

Grøvdal, Lene Melsæther; Schink, Kay Oliver; Pelka, Karin; Husebye, Harald; Latz, Eicke; Stenmark, Harald Alfred. (2016) Moving Tolls - Novel interactors of TLR9 trafficking. CEMIR, NTNU CEMIR Conference 2016 , Trondheim 2016-05-30 - 2016-06-02
Poster

Egeberg, Kjartan Wøllo; Sporsheim, Bjørnar; Espevik, Terje. (2016) STED microscopy of ASC speck inflammasome formation in mouse macrophages. Norsk Biokjemisk Selskap Biokjemisk kontaktmøte 2016 , Tromsø 2016-01-21 - 2016-01-24
Poster

Grøvdal, Lene Melsæther; Schink, Kay Oliver; Pelka, Karin; Husebye, Harald; Latz, Eicke; Stenmark, Harald Alfred. (2016) Moving Tolls - novel interactors of TLR9 trafficking. Norsk Biokjemisk Selskap NBS contact meeting 2016 , Tromsø 2016-01-21 - 2016-01-24
Academic lecture

Niyonzima, Nathalie; Freeley, Simon; Arbore, Giuseppina; Le Friec, Gaelle; Lappegård, Knut Tore; Mollnes, Tom Eirik. (2016) The intracellular C5 system is critical to DAMP sensing and cellular responses in human monocytes. XXVI th International Complement Workshop 2016-09-04 - 2016-09-08
Poster

Bakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Ryan, Liv; Pilely, Katrine; Garred, Peter. (2016) β- CYCLODEXTRIN REDUCES CHOLESTEROL CRYSTAL-INDUCED INFLAMMATION THROUGH MODULATING COMPLEMENT ACTIVATION . CEMIR, NTNU Conference on Molecular Mechanisms of Inflammation , Trondheim 2016-05-30 - 2016-06-02
Academic lecture

Stavik, Benedicte; Holm, Sverre; Espada, Sandra; Iversen, Nina; Sporsheim, Bjørnar; Bjerkeli, Vigdis. (2016) Unconventional mechanisms of targeting atherosclerosis. The 49th Nordic Coagulation Meeting , Oslo 2016-06-16 - 2016-06-18
Poster

Gravastrand, Caroline; Steinkjer, Bjørg; Fure, Hilde; Ryan, Liv; Martins, Catia; Mollnes, Tom Eirik. (2016) Cholesterol crystals induce coagulation activation in a complement-dependent manner. CEMIR Conference on Molecular Mechanisms of Inflammation , Trondheim 2016-05-30 - 2016-06-02
Poster

Gravastrand, Caroline; Teigen, Ellen; Vorkinn, Ingvild; Steinkjer, Bjørg; Gierman, Lobke; Nymo, Siren. (2016) Effect of rapid weight loss in obese individuals with focus on inflammatory receptor expression in peripheral blood leukocytes. Cemir Conference on Molecular Mechanisms of Inflammation , Trondheim 2016-05-30 - 2016-06-02
Poster

Espada Serrano, Sandra; Holm, Sverre; Bjerkeli, Vigdis; Skjelland, Mona; Dahl, Tuva Børresdatter; Iversen, Nina. (2016) ER stress conditions lead to an upregulation of TFPI and is associated with an anti-apoptotic macrophage phenotype. The Scandinavian Society for Atherosclerosis Research (SSAR) 22nd ANNUAL SCANDINAVIAN ATHEROSCLEROSIS CONFERENCE , Humlebæk (Denmark) 2016-04-13 - 2016-04-16

2015

Poster

Yurchenko, Mariya; Skjesol, Astrid; Husebye, Harald; Espevik, Terje. (2015) CD150 REGULATES TYPE I IFN PRODUCTION FROM E.COLI PHAGOSOMES BY AFFECTING TRAM TRAFFICKING. Toll Conference 2015 Targeting Innate Immunity , Marbella 2015-09-30 - 2015-10-03
Poster

Bergstrøm, Bjarte; Ryan, Liv; Espevik, Terje; Stenvik, Jørgen. (2015) Emerging behaviour in multi-PRR signaling. TOLL 2015 2015-09-30 - 2015-10-03
Academic lecture

Bergstrøm, Bjarte; Aune, Marie Hjelmseth; Awuh, Jane Atesoh; Kojen, June Frengen; Ryan, Liv; Flo, Trude Helen. (2015) TLR8 is a sensor for Staphylococcus aureus RNA in human monocytes and macrophages. 12th International Conference on Innate Immunity , Chania 2015-06-19 - 2015-06-24
Poster

Aune, Marie Hjelmseth; Niyonzima, Nathalie; Samstad, Eivind; Bakke, Siril Skaret; Ryan, Liv; Rokstad, Anne Mari. (2015) Crystalline cholesterol is found in atherosclerotic plaques and induces complement mediated inflammation. 15th European Meeting on Complement in Human Disease 2015-06-27 - 2015-06-30
Poster

Nilsen, Nadra J.; Espevik, Terje; Vladimer, G; Stenvik, Jørgen; Orning, M. Pontus A.; Zeid-Kilani, Maria Vanessa. (2015) THE ADAPTOR PROTEINS TRAM AND TRIF MEDIATE TOLL-LIKE RECEPTOR 2 SIGNALING. Wellcome Trust Innate Immune Memory , Hinxton, Cambridge 2015-03-18 - 2015-03-20
Lecture

Nilsen, Nadra J.; Espevik, Terje; Vladimer, G; Ørning, Mathias Pontus; Zeid-Kilani, Maria Vanessa; Bugge, Marit. (2015) THE ADAPTOR PROTEINS TRAM AND TRIF MEDIATE TOLL-LIKE RECEPTOR 2 SIGNALING. UMass Medical School, MA; Universitats Klinikum Freiburg, D Toll2015 Targeting Innate Immunity , Marbella 2015-09-30 - 2015-10-03
Poster

Nilsen, Nadra J.; Espevik, Terje; Gjerdingen, Thea Johannne; Bugge, Marit; Kjønstad, Ingrid Fadum. (2015) A TOLL-LIKE RECEPTOR 7/8 LIGAND SECRETED BY MYELOMA CELLS INDUCES PRIMARY BONE MARROW STROMAL CELLS TO PRODUCE CYTOKINES THAT PROMOTE MYELOMA SURVIVAL. Toll2015 Targeting Innate Immunity 2015-09-30 - 2015-10-03
Academic lecture

Arlov, Øystein; Aachmann, Finn L.; Sundan, Anders; Espevik, Terje; Skjåk-Bræk, Gudmund. (2015) Heparin Analogs from Sulfated Alginates. Department of Chemistry-"La Sapenza" University of Rome 8th European Symposium on Bioploymers , Roma 2015-09-15 - 2015-09-18
Poster

Grøvdal, Lene Melsæther; Schink, Kay Oliver; Pelka, Karin; Husebye, Harald; Latz, Eicke; Stenmark, Harald Alfred. (2015) Moving Tolls - novel interactors of TLR9 trafficking. EMBO The multidisciplinary era of endocytic mechanics and functions , Mandelieu-la-Napoule 2015-09-27 - 2015-10-02
Poster

Grøvdal, Lene Melsæther; Schink, Kay Oliver; Pelka, Karin; Husebye, Harald; Latz, Eicke; Stenmark, Harald Alfred. (2015) Moving Tolls - novel interactors of TLR9 trafficking. EMBO/EMBL Seeing is Believing - Imaging the Processes of Life. , Heidelberg 2015-10-06 - 2015-10-10
Poster

Bakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Ryan, Liv; Damås, Jan Kristian; Latz, Eicke. (2015) β- CYCLODEXTRIN REDUCES CHOLESTEROL CRYSTAL-INDUCED INFLAMMATION THROUGH MODULATING COMPLEMENT ACTIVATION. Toll 2015 2015-09-30 - 2015-10-03
Poster

Egeberg, Kjartan Wøllo; Sporsheim, Bjørnar; Espevik, Terje. (2015) STED microscopy of ASC speck inflammasome formation in mouse macrophages. EMBO EMBL Symposium "Seeing is Believing" , Heidelberg 2015-10-06 - 2015-10-10
Poster

Bugge, Marit; Solli, Helene; Kjønstad, Ingrid F.; Stenvik, Jørgen; Espevik, Terje; Nilsen, Nadra J.. (2015) Metastatic Intestinal Epithelial Cells Express Surface Toll-Like Receptor 3. The University of Massachusetts Medical School Toll 2015 Targeting Innate Immunity , Marbella 2015-09-30 - 2015-10-03
Poster

Skjesol, Astrid; Patane, Francesco; Yurchenko, Mariya; Aune, Marie Hjelmseth; McCaffrey, Mary; Espevik, Terje. (2015) The small GTPase Rab11a and its partner Rab11FIP2 regulate TLR4 signaling pathways. 15th annual meeting of the European Light Microscopy Initiative (ELMI) , Sitges 2015-05-19 - 2015-05-21
Poster

Sporsheim, Bjørnar; Egeberg, Kjartan Wøllo; Espevik, Terje. (2015) STED microscopy of ASC speck inflammasome formation in mouse macrophages. European Light Microscopy Initiative (ELMI) 15th International ELMI meeting , Sitges, Barcelona 2015-05-19 - 2015-05-22
Poster

Skjesol, Astrid; Patane, Francesco; Yurchenko, Mariya; Aune, Marie Hjelmseth; McCaffrey, Mary; Espevik, Terje. (2015) The small GTPase Rab11a and its partner Rab11FIP2 affect TLR4 signaling pathways. TOLL 2015 Targeting innate immunity 2015-09-30 - 2015-10-03
Poster

Sporsheim, Bjørnar; Egeberg, Kjartan Wøllo; Klein, Dionne; Espevik, Terje. (2015) STED microscopy at the Cellular and Molecular Imaging Core facility. Norsk biokjemisk selskap NBS kontaktmøte 2015-02-09 - 2015-02-13
Poster

Bakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Ryan, Liv; Damås, Jan Kristian; Mollnes, Tom Eirik. (2015) Beta-cyclodextrin reduces cholesterol crystal-induced inflammation through modulating complement activation. European Meeting on Complement in Human Disease 2015-06-27 - 2015-06-30
Lecture

Aune, Marie Hjelmseth; Niyonzima, Nathalie; Samstad, Eivind; Nymo, Stig; Ryan, Liv; Bakke, Siril Skaret. (2015) Cholesterol crystals activate the complement system to induce crystal phagocytosis and inflammation. The International Atherosclerosis Society 17TH International Congress on Atherosclerosis 2015 , Amsterdam 2015-05-22 - 2015-05-26

2014

Academic lecture

Espevik, Terje. (2014) Cholesterol crystals induce inflammation: how does it happen and why does it matter?. Rikshospitalet, University of Oslo Research Institute of Internal Medicine seminar , Oslo 2014-03-27 - 2014-03-27
Academic lecture

Espevik, Terje. (2014) Mechanisms involved in the induction of IFN-β by Gram negative- and Gram positive bacteria. University of Gent Seminar , Gent 2014-06-27 - 2014-06-27
Academic lecture

Espevik, Terje. (2014) Toll-like receptor 4 signalling from the endosome. Europeat Tissues Repair Society Europeat Tissues Repair Society meeting , Edinburgh 2014-09-11 - 2014-09-11
Poster

Skjesol, Astrid; McCaffrey, Mary; Espevik, Terje; Husebye, Harald. (2014) Involvement of Rab11FIP2 in TRAM trafficking. European Light Microscopy Initiative , Oslo 2014-05-20 - 2014-05-23
Poster

Skjesol, Astrid; McCaffrey, Mary; Espevik, Terje; Husebye, Harald. (2014) Involvement of Rab11-FIPs (Rab11-family interacting proteins) in TRAM trafficking. NBS Vintermøte 2014 , Røros 2014-01-23 - 2014-01-26
Lecture

Rokstad, Anne Mari; Ørning, Mathias Pontus; Hamad, Shamal; Hoem, Kine Samseth; Steinkjer, Bjørg; Fure, Hilde. (2014) Inflammatory and hemostatic activation induced by alginate microcapsules reveals novel mechanisms underlying their biocompatibility. Agean Conferences Immune responces to biosurfaces: Mechanisms and therapeutic interventions , Crete 2014-09-27 - 2014-10-02
Poster

Egeberg, Kjartan Wøllo; Klein, Dionne C.G.; Espevik, Terje. (2014) Cellular and Molecular Imaging Core Facility (CMIC). UiO ELMI 2014 , Rica Holmenkollen Hotell 2014-05-20 - 2014-05-23
Lecture

Rokstad, Anne Mari; Hamad, Shamal; Steinkjer, Bjørg; Fure, Hilde; Niyonzima, Nathalie; Ørning, Mathias Pontus. (2014) Initial inflammatory and haemostatic mechanisms induced by endogenous and bioartificial surfaces in a whole blood model. NBS Trondheim NBS contact Meeting 2014 , Røros 2014-01-23 - 2014-01-26
Lecture

Aune, Marie Hjelmseth; Samstad, Eivind; Niyonzima, Nathalie; Nymo, Stig Haugset; Ryan, Liv; Lappegård, Knut Tore. (2014) Cholesterol crystals induce complement-dependent inflammasome activation. Norwegian Biochemical Society NBS Contact Meeting , Røros 2014-01-23 - 2014-01-25
Academic lecture

Østvik, Ann Elisabet; Granlund, Atle Van Beelen; Gustafsson, Bjørn I; Espevik, Terje; Damås, Jan Kristian; Mollnes, Tom Eirik. (2014) Lokal Toll-reseptor 3-avhengig syntese av komplement faktor B og lokal komplement aktivering ved inflammatorisk tarmsykdom. Norsk gastroenterologisk forening 41. årsmøte. Norsk gastroenterologis forening , Lillehammer 2014-01-30 - 2014-02-01
Poster

Klein, Dionne; Kers-Rebel, Esther; Espevik, Terje; Husebye, Harald. (2014) The adaptor protein TRAM and LPS-bound CD14 show different trafficking behavior in the MyD88-independent pathway. University of Oslo 14th International Advanced Light Microscopy Meeting , Oslo 2014-05-20 - 2014-05-25
Poster

Østvik, Ann Elisabet; Granlund, Atle Van Beelen; Damås, Jan Kristian; Gustafsson, Björn; Torp, Sverre Helge; Espevik, Terje. (2014) Epithelial Toll-like receptor 3-dependent synthesis of complement factor B and local complement activation in inflammatory bowel disease. European Crohn`s and Colitis Organisation 9th Congress of ECCO , København 2014-02-20 - 2014-02-22
Academic lecture

Espevik, Terje. (2014) Inflammasjon: Alle sykdommers mor. St.Olavs Hospital Fredagsforelesning St. Olavs Hospital , Trondheim 2014-05-16 - 2014-05-16
Academic lecture

Espevik, Terje. (2014) TLR4/TRAM trafficking mechanisms involved in the IFN-β response induced by E.coli. Univeristy of Massachusetts Seminar , Massachusetts 2014-07-26 - 2014-07-26
Academic lecture

Espevik, Terje. (2014) Inflammatory responses induced by cholesterol crystals. Aldemar Royal Olympia 11th International Conference on Innate Immunity , Olympia 2014-06-01 - 2014-06-01
Lecture

Klein, Dionne; Kers-Rebel, Esther; Espevik, Terje; Husebye, Harald. (2014) The signal adaptor protein TRAM and CD14/LPS show different kinetics on endosomes during LPS induced TLR4 signaling. NBS Norwegian Biochemical Society Meeting , Røros 2014-01-23 - 2014-01-26
Poster

Klein, Dionne; Egeberg, Kjartan Wøllo; Espevik, Terje. (2014) Cellular and Molecular Imaging Core Facility (CMIC). NBS Norwegian Biochemical Society Meeting , Røros 2014-01-23 - 2014-01-26

2013

Academic lecture

Aune, Marie Hjelmseth; Samstad, Eivind; Niyonzima, Nathalie; Nymo, Stig; Ryan, Liv; Lappegård, Knut Tore. (2013) Cholesterol crystals induce complement-dependent inflammasome activation. UMass and abcam Inflammasomes in health and disease , Boston 2013-06-24 - 2013-06-25
Lecture

Klein, Dionne; Kers, Esther; Espevik, Terje; Husebye, Harald. (2013) Dynamics of toll-like receptor 4 and its adaptor protein TRAM. Klaus Qvortrup The Annual Meeting of the Nordic Microscopy Society SCANDEM 2013 , Copenhagen 2013-06-10 - 2013-06-14
Poster

Klein, Dionne; Espevik, Terje. (2013) Cellular and Molecular Imaging Core Facility (CMIC). Klaus Qvortrup The Annual Meeting of the Nordic Microscopy Society SCANDEM 2013 , Copenhagen 2013-06-10 - 2013-06-14
Interview

Weisser, Agnethe; Espevik, Terje; Flo, Trude Helen. (2013) Se krigercellene gå til angrep. Adressa Adressa [Newspaper] 2013-03-15
Lecture

Espevik, Terje. (2013) CEMIR - a new centre of excellence on inflammation research. CEMIR opening seminar, NTNU 2013-10-14 -
Lecture

Espevik, Terje. (2013) Centre of Molecular Inflammation Research. SFF forum, Oslo 2013-11-05 -
Lecture

Espevik, Terje. (2013) Immunrespons ved sepsis. Infeksjonsmøte, Oslo 2013-11-08 -
Interview

Weisser, Agnethe; Espevik, Terje. (2013) Senter for Molekylær Inflammasjonsforskning. [Newspaper] 2013-03-13
Interview

Jakobsen, Siw Ellen; Espevik, Terje; Flo, Trude Helen. (2013) Når forsvarerne blir fienden. Bladet Forskning Bladet Forskning [Business/trade/industry journal] 2013-09-01
Poster

Bugge, Marit; Nilsen, Nadra; Espevik, Terje. (2013) A potential role for TLR3 expression and TLR3 mediated responses in the progression of colorectal cancer. Keystone Symposia on Cancer Immunology and Immunotherapy , Vancouver 2013-01-27 - 2013-02-01
Poster

Skjesol, Astrid; Starheim, Kristian Kobbenes; Klein, Dionne C.G.; McCaffrey, Mary; Espevik, Terje; Husebye, Harald. (2013) The small GTPase Rab11a integrates TRAM trafficking between TGN and endosome in LPS induced TRAM-TRIF-signaling. EMBO Systems Dynamics in Endocytosis 2013-09-29 - 2013-10-04
Academic lecture

Espevik, Terje. (2013) Complement dependency of cholesterol crystal induced inflammation. Gjesteforelesning ved University of Massachusetts 2013-01-15 -
Lecture

Espevik, Terje. (2013) Inflammation responses. MBI 8001 PhD kurs Universitetet i Tromsø 2013-06-05 -
Academic lecture

Espevik, Terje. (2013) Introduction to Innate Immunity. PhD course Innate Immunity, University of Copenhagen 2013-01-20 -
Academic lecture

Espevik, Terje. (2013) TLRs, NLRs, PAMPs and DAMPS in innate immunity. PhD course Innate Immunity, University of Copenhagen 2013-03-23 -
Academic lecture

Espevik, Terje. (2013) Cholesterol crystal-mediated inflammation: relationship to development of atherosclerosis. 6th International Conference on Complement Therapeutics 2013-06-18 - 2013-06-23
Academic lecture

Espevik, Terje. (2013) Staphylococcus aureus triggers IFN-beta induction in human monocytes by phagosomal TLR8 signaling. 10th International Conference on Innate Immunity 2013-06-25 -
Academic lecture

Espevik, Terje. (2013) Kolesterolkrystaller som årsak til inflammasjon ved aterosklerose. Åpning av Jebsen senter, Universitetet i Oslo 2013-10-25 -
Academic lecture

Espevik, Terje. (2013) Toll-like receptor signalling in innate and adaptive immunity. PhD kurs: Mechanisms of cellular signal transduction, Universitetet i Oslo 2013-10-29 -
Academic lecture

Espevik, Terje. (2013) Involvement of cholesterol crystals in atherosclerosis. Gjesteforelesning ved Boston University 2013-01-16 -
Popular scientific lecture

Espevik, Terje. (2013) CEMIR - Centre of Molecular Inflammation Research. Offisiell åpning av de 4 nye SFF sentrene ved NTNU 2013-06-10 -

2012

Academic lecture

Husebye, Harald; Espevik, Terje. (2012) Mechanisms behind toll-like receptor 4 (TLR4) signaling. Kemijski inštitut Hajdrihova 19 SI-1001 Ljubljana Winter school 2012 on innate immunity and synthetic biology , Pokljuka 2012-03-21 - 2012-03-23
Poster

Klein, Dionne; Oestvang, Janne; Espevik, Terje. (2012) Cellular and Molecular Imaging Core Facility (CMIC). St. Olavs Hospital Regional forskningskonferanse 2012 i Helse Midt-Norge , Trondheim 2012-06-05 - 2012-06-06
Poster

Østvik, Ann Elisabet; Granlund, Atle; Torp, Sverre Helge; Flatberg, Arnar; Waldum, Helge; Espevik, Terje. (2012) Induction of Lipocalin-2 in colonic epithelial cells in inflammatory bowel disease. Crohn`s and Colitis Foundation of America (CCFA) 2012 Advances in Inflammatory Bowel Disease Cohn`s and Colitis Fundation`s National Clinical & Research Conference , Miami 2012-12-14 - 2012-12-17
Academic lecture

Klein, Dionne; Egeberg, Kjartan Wøllo; Espevik, Terje. (2012) Cellular and Molecular Imaging Core Facility (CMIC). MIC Bergen 5th NorMIC Meeting , Bergen 2012-10-25 - 2012-10-26
Poster

Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Lambris, John D.. (2012) Poly-cation containing alginate microcapsules induce cytokines by a complement-dependent mechanism. Aegean conferences XXIV. International Complement Workshop , Chania, Crete, Greece, october 10-15, 2012 2012-10-10 - 2012-10-15
Academic lecture

Klein, Dionne; Kers-Rebel, Esther; Espevik, Terje; Husebye, Harald. (2012) Dynamics of Toll-like receptor 4 and its adaptor protein TRAM. IKM Instituttseminar , Trondheim 2012-05-09 -
Academic lecture

Klein, Dionne; Kers-Rebel, Esther; Espevik, Terje; Husebye, Harald. (2012) FRAP study of TLR4 dynamics. MIC Bergen 5th NorMIC Meeting , Bergen 2012-10-25 - 2012-10-26
Academic lecture

Husebye, Harald; Espevik, terje. (2012) Mechanisms behind TLR4 induced IFN-β signaling. 5th NorMIC Meeting. , Bergen 2012-10-25 - 2012-10-26

2011

Poster

Husebye, Harald; Aune, Marie Hjelmseth; Steinvik, Jørgen; Espevik, Terje. (2011) The small GTPase Rab11a is involved in LPS induced IFN-β production. UMASS Deconding Innate Immunity, Riva del Garda, Italy, May 4-7, 2011 , Riva del Garda, 2011-05-04 - 2011-05-07
Poster

Husebye, Harald; Aune, Marie Hjelmseth; Stenvik, Jørgen; Espevik, Terje. (2011) The small GTPase Rab11a is involved in LPS induced IFN-β production. ISB ISB retreat, , Fort Worden, Washington 2011-09-14 - 2011-09-15
Poster

Klein, Dionne; Rebel, Esther; Espevik, Terje; Husebye, Harald. (2011) Dynamics of Toll-like receptor 4 and its adaptor protein TRAM. Tromsø University NorMIC Annual Meeting , Tromsø 2011-10-20 - 2011-10-21
Academic lecture

Rokstad, Anne Mari; Ryan, Liv; Steinkjer, Bjørg; Brekke, Ole Lars; Qi, Meirigeng; Oberholzer, José. (2011) Inflammatory responses of alginate microspehers evaluated by a human and baboon whole blood model. IPITA Council 13th world Congress of IPITA International Pancreas and Islets Transplant Association , Prague 2011-06-01 - 2011-06-04

2010

Poster

Sandanger, Øystein; Ranheim, T; Ving, L R; Florholmen, Geir; Christensen, Geir Arve; Dahl, Christen Peder. (2010) Identification and characterization of the NLRP3 inflammasome in cardiac fibroblasts. Center for Heart Failure Research 8th Annual Center for Heart Failure Research Symposium , Oslo 2010-10-01 - 2010-10-01
Academic lecture

Anthonsen, Marit Walbye; Johnsen, Ingvild Bjellmo; nguyen, thuy than; Bergstrøm, Bjarte Aune; Espevik, Terje. (2010) Roles of the tyrosine kinase c-Src in innate immune responses. Århus Universitet, Inst medisinsk mikrobiologi og immunologi Mechanisms of innate antiviral immunity , Århus 2010-05-19 - 2010-05-20
Academic lecture

Nilsen, Nadra; Espevik, Terje; Lien, Egil. (2010) The Adaptor Proteins TRAM and TRIF mediate Toll-Like Receptor 2- induced RANTES/CCL5 Release. International Congress of Immunology 14th International Congress of Immunology , Kobe 2010-08-22 - 2010-08-27
Academic lecture

Flo, Trude Helen; Awuh, Jane Atesoh; Halaas, Øyvind; Steigedal, Magnus; Cangelosi, Gerard; Ryan, Liv. (2010) Intracellular mycobacterium avium intersect transferrin in the Rab11+recycling endocytotic pathway and avoid lipocalin 2 trafficking the lysosomal pathway. Norsk Biokjemisk Selskap NBS kontaktmøte 2010 , Storefjell 2010-01-17 - 2010-01-21
Poster

Salvesen, Bodil; Stenvik, Jørgen; Rossetti, Carlo; Saugstad, Ola Didrik; Espevik, Terje; Mollnes, Tom Eirik. (2010) Meconium-Induced Release of Cytokines, Chemokines and Growth Facteors is Mediated by the TRL4/MD-2 Complex in a CD14-Dependent Manner. Pediatric Academic Societies Annual Meeting Pediatric Academic Societies Annual Meeting , Vancouver, BC 2010-05-01 - 2010-05-04

2009

Academic lecture

Aune, Marie Hjelmseth; Husebye, Harald; Espevik, Terje. (2009) Trafficking of TLR4 in human monocytes upon activation by Escherichia coli. Universitetet i Bergen The endocytic pathway in health and disease , Voss 2009-03-18 - 2009-03-21
Academic lecture

Aune, Marie Hjelmseth; Husebye, Harald; Halaas, Øyvind; Samstad, Eivind; Latz, Eicke; Stenmark, Harald. (2009) Rab11a controls TLR4 recruitment to Escherichia coli containing phagosomes in human monocytes. Norsk biokjemisk selskap NBS, kontaktmøtet 2009 , Røros 2009-01-28 - 2009-01-30
Academic lecture

Espevik, Terje. (2009) The Rab11a GTPase regulates trafficking of TLR4 to phagosomes containing E. Coli. 6th International Innate Immunity Conference , Kreta 2009-06-01 -
Academic lecture

Espevik, Terje. (2009) Inflammatory responses. Department of biotechnology National Institute of Chemistry Invited lecture at Department of biotechnology National Institute of Chemistry , Luubljana 2009-03-01 -
Academic lecture

Espevik, Terje. (2009) Vert-mikrobe interaksjoner. Norsk Forening for Mikrobiologi Norsk Forening for Mikrobiologi sitt vintermøte , Trondheim 2009-02-06 -
Academic lecture

Espevik, Terje. (2009) The endosomal pathway and innate immunity. University of Bergen The Endocytic Pathway in Health and Disease , Voss 2009-03-18 - 2009-03-21
Academic lecture

Espevik, Terje. (2009) Inflammatory responses against Gram negative bacteria. Norsk Biokjemisk Selskap Norsk Biokjemisk Selskaps Kontaktmøte , Røros 2009-01-29 - 2009-02-01
Academic lecture

Espevik, Terje. (2009) Regulation of TLR4 trafficking and signaling. Institutt for Immunologi, UiO Seminar ved Institutt for Immunologi , Oslo 2009-06-01 -
Academic lecture

Klein, Dionne; Øvrebø, Kirsti Marie; Latz, Eicke; Stokke, Bjørn Torger; Espevik, Terje. (2009) Immunostimulatory CpG DNA studied by atomic force microscopy and fluorescence correlation spectroscopy. 2nd annual NorMIC meeting , Stavanger 2009-11-12 - 2009-11-13
Poster

Klein, Dionne; Øvrebø, Kirsti Marie; Latz, Eicke; Espevik, Terje; Stokke, Bjørn Torger. (2009) Immunostimulatory CpG-DNA and its interaction with Toll-like receptor 9 investigated by AFM. International Scanning Probe Microscopy Conference , Madrid 2009-06-17 - 2009-06-19
Poster

Klein, Dionne; Latz, Eicke; Stokke, Bjørn Torger; Espevik, Terje. (2009) Immunostimulatory CpG-DNA studied by AFM and FCS. 12th Carl Zeiss sponsored workshop on FCS and related methods , Cargese 2009-10-12 - 2009-10-16
Poster

Awuh, Jane Atesoh; Halaas, Øyvind; Haug, Markus; Flo, Trude Helen; Steigedal, Magnus; Brech, Andreas. (2009) Intracellular Mycobacterium avium enters the Rab11+ Recycling Endocytic Pathway to Access Transferrin and Escape from Lcn2 trafficking the Lysosomal Pathway. 4th Conference on Global Health and Vaccination Research (GlobVac) , Oslo 2009-11-30 - 2009-12-02
Poster

Halaas, Ø.; Steigedal, Magnus; Haug, Markus; Awuh, Jane Atesoh; Husebye, Harald; Ryan, Liv. (2009) Intracellular Mycobacterium avium Enters the Rab11+ Recycling End¬ocytic Pathway to Access Transferrin and Escape from Lcn2 trafficking the Lysosomal Pathway. American Society of Microbiology ASM General Meeting , Philadelphia 2009-05-17 - 2009-05-21

2008

Academic lecture

Espevik, Terje. (2008) Membrantrafikkering i relasjon til immunreaksjoner - nytt FUGE prosjekt. IKM Tirsdagsmøte for DMF, NTNU og St. Olavs Hospital , Trondheim 2008-01-08 -
Academic lecture

Husebye, Harald; Hjelmseth, M; Samstad, Eivind Ottersen; Halaas, Øyvind; Latz, Eicke; Stenmark, Harald. (2008) Role of Rab11 in signalling and intracellular trafficking of Toll-like receptor 4. Toll2008 2008-09-24 - 2008-09-27
Academic lecture

Steigedal, Magnus; Flo, Trude Helen; Espevik, Terje; Rognstad, Øyvind Bakken. (2008) Lipocalin 2- a novel innate immunity protein with antimicropbial effect: Role in urinary tract infection (UTI). Norsk Biokjemisk Selskap The Norwegian Biochemical Society 44th Contact meeting , Lillehammer 2008-01-17 - 2008-01-20
Academic lecture

Klein, Dionne C.G.; Øvrebø, Kirsti Marie; Latz, Eicke; Espevik, Terje; Stokke, Bjørn Torger. (2008) Toll-like receptor 9 and its ligand CpG-DNA studied with AFM. Veeco Veeco Scandinavian Conference, Developments in Atomic Force Microscopy for advanced imaging techniques , Trondheim 2008-10-30 - 2008-10-31
Poster

Klein, Dionne C.G.; Øvrebø, Kirsti Marie; Latz, Eicke; Espevik, Terje; Stokke, Bjørn Torger. (2008) Toll-like receptor 9 and its ligand CpG-DNA studied with atomic force microscopy. Catharina Davies Normic National User Meeting NTNU , Trondheim 2008-11-11 - 2008-11-12
Poster

Flo, Trude Helen; Halaas, Øyvind; Steigedal, Magnus; Espevik, Terje; Ryan, Liv; Strong, Roland. (2008) Lipocalin 2 protects against mycobacterial infections during the acute phase, but not in long term chronic infections. Luke A.J. O'Neill, Jürg Tscopp, Shizou Akira Keystone Symposia on Innate Immunity: Signaling Mechanisms , Keystone, Colorado 2008-02-24 - 2008-02-29
Poster

Skjærvold, Nils Kristian; Tyvold, Stig Sverre; Grønbech, Jon Erik; Espevik, Terje; Aadahl, Petter; Solligård, Erik. (2008) Detection of cytokines in the intestinal lumen by microdialysis. ESICM Annual Congress of The European Society of Intensive Care Medicine , Lisboa 2008-09-15 - 2008-09-18
Poster

Steigedal, Magnus; Flo, Trude Helen; Halaas, Øyvind; Ryan, Liv; Espevik, Terje. (2008) Mycobacteria are Lipocalin 2-sensitive but evade long term growth suppression by excluding lipocalin 2 from their intracellular compartment. American Society for Microbiology ASM General Meeting , Boston 2008-06-01 - 2008-06-05
Poster

Nilsen, Nadra; Deininger, Susanne; Nonstad, Unni; Skjeldal, Frode; Husebye, Harald; Rodionov, Dmitrii. (2008) Toll-like receptor 2 signaling occurs preferentially at the plasma membrane, independent of internalization, and is facilitated by both CD36 and CD14. UMASS Medical School / Fundacao Calouste Gulbenkian TOLL2008 , Caiscais 2008-09-24 - 2008-09-27
Poster

Iversen, Ann-Charlotte; Steinkjer, Bjørg; Nilsen, Nadra; Bohnhorst, Janne Øvrebø; Moen, Siv Helen; Vik, Randi. (2008) A proviral role for CpG in cytomegalovirus infection. UMASS, Boston, MA Toll 2008 Conference , Cascais 2008-09-24 - 2008-09-27
Poster

Rokstad, Anne Mari; Steinkjer, Bjørg; Lien, Egil; Espevik, Terje. (2008) TOLL like receptor 4 is involved in inflammatory reactions (overgrowth) against alginate capsules. Neal Silverman, University of Massachusetts Medical school TOLL2008 Meeting; Recent advances in Pattern recognition , Lisboa 2008-09-24 - 2008-09-27

2007

Documentary

Espevik, Terje. (2007) "Norges mest siterte". Universitetsavisa, NTNU Universitetsavisa, NTNU [Newspaper] 2007-05-15
Academic lecture

Espevik, Terje. (2007) Intracellular trafficking and signalling of Toll-like receptors. Fleischers hotell "From innate to specific immunity" , Voss 2007-03-21 - 2007-03-24
Academic lecture

Espevik, Terje. (2007) Cellular trafficking of Toll-like receptors in relation to signalling. Porto Heli Conference Center, 4th International Workshop on Complement Associated Diseases, Animal Models, and Therapeutics , Porto Heli 2007-06-10 - 2007-06-15
Academic lecture

Espevik, Terje. (2007) Signalmekanismer for Toll-lignende reseptor 4 i relasjon til sepsis. Invitert, Nordland Sykehus 2007-10-29 - 2007-10-29
Academic lecture

Husebye, Harald; Halaas, Øyvind; Stenmark, Harald; Tunheim, G; Sandanger, Øystein; Brech, A. (2007) Functions associated with intracellular trafficking of Toll-like receptor 4. Poster award 3rd price. Norsk Biokjemisk Selskap Biokjemisk kontaktmøte , Lillehammer 2007-02-01 - 2007-02-04
Academic lecture

Espevik, Terje. (2007) Membrantrafikkering i relasjon til immunreaksjoner. Institutt for kreftforskning og molekylær medisin, DMF, NTNU Tirsdagsmøte, Institutt for kreftforskning og molekylær medisin , Trondheim 2007-10-17 - 2007-10-17
Poster

Klein, Dionne C.G.; Latz, Eicke; Espevik, Terje; Stokke, Bjørn Torger. (2007) Toll-like receptor 9 and its ligand CpG-DNA studied with AFM and FCS. European Biophysical Society 6th European Biophysics Congress , London 2007-07-14 - 2007-07-18
Poster

Klein, Dionne C.G.; Latz, Eicke; Espevik, Terje; Stokke, Bjørn Torger. (2007) Toll-like receptor 9 and its ligand CpG-DNA studied with AFM and FCS. 9th Annual Linz Winter Workshop , Linz 2007-02-02 - 2007-02-05
Poster

Bohnhorst, Janne Øvrebø; Moen, Siv H; Espevik, Terje; Sundan, Anders. (2007) Bone morphogenetic protein(BMP)-4 and BMP-6 may reduce plasma cell differentiation in B cells. Mantovani, Instituto Clinico Humanitas Inflammation and cancer , Milano 2007-11-08 - 2007-11-09
Poster

Nilsen, Asbjørn Magne; Vik, Randi; Behrens, Carl; Drabløs, Per Arne; Espevik, Terje. (2007) BERYLLIUM SENSITIVITY AMONG WORKERS AT A NORWEGIAN ALUMINIUM SMELTER. Statens arbeidsmiljøinstitutt (STAMI) m fl EHSARPA 2007 , Loen 2007-09-10 - 2007-09-12
Popular scientific lecture

Husebye, Harald; Espevik, Terje. (2007) Toll-like receptor functions involving endosomes. TOLL 2007 Congress 2007-03-04 - 2007-03-07

2006

Academic lecture

Espevik, Terje. (2006) Toll-like receptors: sensors for pathogens. University of Oslo 2006-02-22 -
Academic lecture

Espevik, Terje. (2006) Immunostimulating alginates: Highlights from our research and some future perspectives. NTNU Seminar i anledning professor G. Skjåk-Bræks 60 yr anniversary , NTNU 2006-04-20 - 2006-04-20
Academic lecture

Espevik, Terje. (2006) Intracellular trafficking and signalling of Toll-like receptors. EMBO Conference, Macro Molecular Complexes in Microbial Pathogenesis Membrane Trafficking and Cell Singalling. , S. Feliu de Guixols 2006-09-22 -
Academic lecture

Rokstad, Anne Mari Aukan; Donati, Ivan; Borgogna, Massilimo; Oberholzer, José; Strand, Berit Løkensgard; Espevik, Terje. (2006) Cell-compatible covalent alginate beads obtained from a chemoenzymatically engineered alginate. Bioencapsulation research group XIV International workshop on bioencapsulation & COST 865 meeting , Lausanne 2006-10-05 - 2006-10-07
Programme participation

Espevik, Terje. (2006) Kreftforskning halveres. NRK Trøndelag NRK Trøndelag [Radio] 2006-10-09
Poster

Klein, Dionne C.G.; Stokke, Bjørn Torger; Espevik, Terje. (2006) Visualization of the first step in activation of Toll-like receptors by atomic force microscopy and confocal microscopy. Norwegian Biophysics Meeting , Kongsvold 2006-03-15 - 2006-03-17
Poster

Klein, Dionne C.G.; Stokke, Bjørn Torger; Espevik, Terje. (2006) Activation of Toll-like receptors studied by atomic force microscopy and confocal microscopy. Douglas Golenbock Toll 2006, Recent Advances in Pattern Recognition , Salvador 2006-03-04 - 2006-03-07
Poster

Klein, Dionne C.G.; Latz, Eicke; Stokke, Bjørn Torger; Espevik, Terje. (2006) Binding of different classes of CpG-DNA to Toll-like receptor 9 investigated with fluorescence correlation spectroscopy. AlbaNova University Center 9th Carl Zeiss sponsored workshop on FCS and related methods , Stockholm 2006-12-04 - 2006-12-06
Poster

Husebye, Harald; Halaas, Øyvind; Stenmark, Harald; Tunheim, G; Sandanger, Øystein; Brech, A. (2006) Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity. Toll in Brazil Toll2006 Meeting , Salvador 2006-03-04 -
Poster

Husebye, Harald; Halaas, Øyvind; Stenmark, Harald; Tunheim, G; Sandanger, Øystein; Brech, A. (2006) Functions associated with intracellular traficking of Toll-like receptor 4. EMBO EMBO Conference "Interface of Cell Biology and Cellular Microbiology: Macormolecular Complexes in Microbial Pathogenesis, Membrane Trafficking and Cell Signaling" , Sant Feliu de Guixols 2006-09-23 - 2006-09-28
Poster

Husebye, Harald; Halaas, Øyvind; Stenmark, Harald; Tunheim, G; Sandanger, Øystein; Brech, A. (2006) Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity. NBS Norsk Biokjemisk Selskap Trøndelag , Trondheim 2006-09-18 -
Poster

Johnsen, Ingvild Bjellmo; Ringdal, Monika; Nguyen, Thank Thuy Thi; Tryggestad, Anne Merete Aaland; Lien, Egil; Espevik, Terje. (2006) Double-stranded RNA induces association of TLR3 with c-Src tyrosine kinase on endosomes to initiate antiviral signaling. Toll2006 - Recent Advances in Pattern Recognition , Salvador 2006-03-04 - 2006-03-07
Popular scientific lecture

Espevik, Terje. (2006) Endocytosis and degradation of the LPS receptor complex - how and why?. University of Massachusetts 2006-07-15 -
Popular scientific lecture

Espevik, Terje. (2006) Functions of Toll-like receptor 4 involving endosomes. 4th International Conference on Innate Immunity , Corfu 2006-06-03 -
Popular scientific lecture

Sandanger, Øystein; Ryan, Liv; Halaas, Øyvind; Iversen, Ann-Charlotte; Bohnhorst, Janne Øvrebø; Espevik, Terje. (2006) Characterization of MD-2 localization and expression using a newly developed monoclonal antibody (IIC1). Keystone Symposium , Bannf Springs 2006-01-19 -

2005

Academic lecture

Espevik, Terje. (2005) Toll reseptorforskning - før, nå og framover. Tirsdagsmøtet , Trondheim 2005-01-18 - 2005-01-18
Academic lecture

Espevik, Terje. (2005) Medfødt immunitet studert ved hjelp av optiske avbildingsteknikker. Den lokale FUGE komitèen Lokal FUGE komitè , Bårdshaug 2005-03-03 - 2005-03-04
Academic lecture

Espevik, Terje. (2005) How can we use systems biology to study host defence mechanisms of innate immunity. NTNU møte , Trondheim 2005-06-10 - 2005-06-10
Academic lecture

Espevik, Terje. (2005) Hvordan oppdager det medfødte immunsystemet mikroorganismer. Institutt for bioteknologi på Gløshaugen, seminar , Trondherim 2005-04-14 - 2005-04-14
Academic lecture

Espevik, Terje. (2005) Toll-like receptors in inflammatory responses. Cardiff Institute of Tissue Engineering and Repair Invitert til å holde foredrag , Wales College of Medicine 2005-11-03 - 2005-11-03
Academic lecture

Espevik, Terje. (2005) Endocytosis and degradation of the LPS receptor complex, how and why?. EU-prosjekt EU-prosjektmøte i AMIS 2005-11-20 - 2005-11-23
Poster

Pukstad, Brita; Ryan, Liv; Jones, S; Thomas, DW; Harding, KG; Espevik, Terje. (2005) An investigation of toll-like receptor interaction with bacteria in the pathogenesis of chronic leg ulcers. NBS Vintermøte i Tromsø , Tromsø 2005-01-13 - 2005-01-16
Poster

Espevik, Terje; Husebye, Harald; Bohnhorst, Janne Øvrebø; et al., diverse. (2005) Functions of Toll-like receptors in the immune system. NBS The Norwegian Biochemical Society 41st Contact Meeting , Tromsø 2005-01-13 - 2005-01-16
Poster

Bohnhorst, Janne Øvrebø; Fløttum, Marianne; Rasmussen, T; Børset, Magne; Sundan, Anders; Espevik, Terje. (2005) A possible role of toll-like receptors in multiple myeloma. NBS The Norwegian Biochemical Society 41st Contact Meeting , Tromsø 2005-01-13 - 2005-01-16
Poster

Johnsen, Ingvild Bjellmo; Ringdal, Monika; Tryggestad, Anne Merete; Lien, Egil; Espevik, Terje; Anthonsen, Marit Walbye. (2005) Double-stranded RNA induces association of TLR3 with c-Src tyrosine kinase on endosomes to initate antiviral signaling. NBS The Norwegian Biochemical Society 41st Contact Meeting , Tromsø 2005-01-13 - 2005-01-16
Poster

Nguyen, Thank Thuy Thi; Johnsen, Ingvild Bjellmo; Hagen, Lars; Torseth, Kathrin; Espevik, Terje; Slupphaug, Geir. (2005) Identification of novel proteins associated with a pathogen patten recognition receptor mediating antiviral immune responses. NBS The Norwegian Biochemical Society 41st Contact Meeting , Tromsø 2005-01-13 - 2005-01-16
Poster

Rokstad, Anne Mari Aukan; Strand, Berit Løkensgard; Rian, Kristin; Steinkjer, Bjørg; Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund. (2005) Making alginate bioreactors for treatment of brain tumours: strategies for optimalisation of the system. NBS The Norwegian Biochemical Society 41st Contact Meeting , Tromsø 2005-01-13 - 2005-01-16
Poster

Johnsen, Ingvild Bjellmo; Ringdal, Monika; Tryggestad, Anne Merete Aaland; Nguyen, Thank Thuy Thi; Lien, Egil; Espevik, Terje. (2005) Double-stranded RNA induces association of TLR3 with c-Src tyrosine kinase on endosomes to initate antiviral signaling. 2nd ESF Functional Genomics Conference , Oslo 2005-09-06 - 2005-09-10
Academic lecture

Espevik, Terje. (2005) Functions of Toll-like receptors in the immune system. NBS The Norwegian Biochemical Society 41st Contact Meeting , Tromsø 2005-01-13 - 2005-01-16

2004

Poster

Johnsen, Ingvild Bjellmo; Ringdal, Monika; Tryggestad, Anne Merete Aaland; Espevik, Terje; Anthonsen, Marit Walbye. (2004) Double-stranded RNA induces TLR3-mediated c-Src-dependent Akt activation in human monocyte-derived dendritic cells. Toll 2004 , Taormina, Sicily 2004-05-08 - 2004-05-11
Academic lecture

Bohnhorst, Janne Øvrebø; Fløttum, M; Rasmussen, T; Børset, Magne; Sundan, Anders; Espevik, Terje. (2004) Abnormal expression of toll-like receptors in multiple myeloma. Toll Meeting 2004 , Sicilia 2004-05-08 - 2004-05-11
Academic lecture

Bohnhorst, Janne Øvrebø; Fløttum, M; Rasmussen, T; Børset, Magne; Sundan, Anders; Espevik, Terje. (2004) Abnormal expression of toll-like receptors in multiple myeloma. 12th International Congress of Immunology 2004-07-01 -
Academic lecture

Nilsen, Nadra; Espevik, Terje. (2004) Molecular associations of lipopeptides with CD14 and TLR2. Toll 2004 , Sicilia 2004-05-08 - 2004-05-11
Academic lecture

Pukstad, Brita; Ryan, Liv; Espevik, Terje. (2004) An investigation of toll-like receptor interaction with bacteria in the pathogenesis of chronic leg ulcers. WUWHS (World Union Wound Healing Society) , Paris 2004-07-09 -
Academic lecture

Halaas, Øyvind; Husebye, Harald; Stenmark, Harald; Latz, E; Espevik, Terje. (2004) Molecular mechanisms for endocytosis of the LPS receptor complex. 12th International Congress of Immunology 2004-07-08 - 2004-07-11
Academic lecture

Husebye, Harald; Halaas, Øyvind; Espevik, Terje. (2004) Molecular mechanisms for endocytosis of the LPS receptor complex. Toll 2004 , Sicilia 2004-05-08 - 2004-05-11
Academic lecture

Espevik, Terje. (2004) Toll-like receptors in inflammatory responses, signalling mechanisms, oncology - cardiology - neurology - osteoporosis - diabetes. Rikshospitalet 2004-10-28 - 2004-10-29
Academic lecture

Nilsen, Nadra; Nonstad, U; Knetter, Cathrine; Sundan, Anders; Espevik, Terje; Lien, Egil. (2004) Lipopolysaccharide- and dsRNA-Induced Upregulation of Mouse Tollike Receptor 2 is Myeloid Differentiation Factor 88-Independent. Toll 2004 , Sicilia 2004-05-08 - 2004-05-11
Academic lecture

Espevik, Terje. (2004) Trafficking of Toll-like receptors. 6th World Congress on Trauma, Shock, Inflammation and Sepsis - Patho 2004-03-02 - 2004-03-06
Academic lecture

Johnsen, Ingvild Bjellmo; Ringstad, M; Tryggestad, A; Espevik, Terje; Anthonsen, Marit Walbye. (2004) Double-stranded RNA induces TLR-3-mediated c-Src-dependent Akt activation in human monocyte-derived dindritic cells. Toll 2004 , Sicilia 2004-05-08 - 2004-05-11
Academic lecture

Johnsen, Ingvild Bjellmo; Lien, Egil; Espevik, Terje; Anthonsen, Marit Walbye. (2004) Double-stranded RNA is internalized through clathrin-mediated endocytosis and trafficks to tubular lysosomes. Toll 2004 2004-05-08 - 2004-05-11
Academic lecture

Ryan, Liv; Vik, R; Moen, S; Steinkjer, B; Iversen, Ann-Charlotte; Sundan, Anders. (2004) Generation and characterization of new monoclonal antibodies against human MD-2. Toll 2004 , Sicilia 2004-05-08 - 2004-05-11
Academic lecture

Johnsen, Ingvild Bjellmo; Espevik, Terje; Anthonsen, Marit Walbye. (2004) Konfokalmikroskopi - Antiviral immunrespons. LBK, NTNU Interessegruppe for konfokalmikroskopi , Trondheim 2004-05-05 - 2004-05-05
Poster

Dahle, Maria K; Øverland, Gunhild; Myhre, Anders; Stuestøl, Jon Fredrik; Espevik, Terje; Hartung, T. (2004) TOLL-LIKE RECEPTOR REGULATION AND SIGNALLING IN KUPFFER CELLS. Surgical Infection Society, 23rd Annual Meeting in San-Antonio , San Antonio, Texas,USA 2004-04-12 -

2003

Academic lecture

Strand, Berit Løkensgard; Mørch, Yrr Asbjørg; Espevik, Terje; Skjåk-Bræk, Gudmund. (2003) Improvement of alginate microcapsules using Ba2+ - and Sr2+ -ions and biopolymer engineering. 6th International Congress of the Cell Transplant Society , Atlanta 2003-03-03 - 2003-03-06
Poster

Manoukian, M; Triantafilou, M; Triantafilou, K; Mackie, A; Nilsen, Nadra; Espevik, Terje. (2003) Molecular mechanisms of lipopeptide interaction with CD14 and TLR2. 34th Annual Meeting of the German Society of Immunology , Berlin, Germany 2003-09-27 -
Poster

Strand, Berit Løkensgard; Mørch, Yrr Asbjørg; Espevik, Terje; Skjåk-Bræk, Gudmund. (2003) Improvement of alginate microcapsules using Ba2+- and Sr2+-ions and biopolymer engineering. 6th International Congress of the Cell Transplant Society , Atlanta, USA 2003-03-15 -
Academic lecture

Espevik, Terje. (2003) Polymer og kompositter - myke materialer - anvendelser innen medisinsk teknologi. Seminar på Jægtvolden , Jægtvolden, Inderøy 2003-10-24 -
Academic lecture

Espevik, Terje. (2003) Applications of fluorescent Toll gene constructs�. Host Pathogen Interactions , Marburg, Tyrskland 2003-10-19 -
Academic lecture

Espevik, Terje. (2003) Cell Distributions and Functions of Toll-like Receptor 4 Studied by Fluorescent Gene Constructs. Karolinska Institutet, Nobel Symposium no 124, Septicemia and Shock: Pathogenesis and Novel Therapeutic Strategies , Stockholm, Sverige 2003-05-17 -
Popular scientific lecture

Espevik, Terje. (2003) Toll lignende reseptor 4: kroppens sensor for endotoksin. Biokjemisk interessegruppe ved Rikshospitalet , Oslo 2003-05-08 -
Popular scientific lecture

Espevik, Terje. (2003) Toll-like receptors and innate immunity. Teveltun Meeting , Meråker, Norge 2003-05-20 -

2002

Academic lecture

Espevik, Terje. (2002) Monocytes stimulated with Group B streptococci or IFNs release soluble TRAIL. HOSPATH Mid Term Evaluation of Project , Trondheim, Norge 2002-09-11 -
Academic lecture

Espevik, Terje. (2002) Toll-like receptors. The 10th Congress of European Shock Society. , Oslo, Norge 2002-09-28 -
Academic lecture

Espevik, Terje. (2002) Use of alginates in wound healing. Invited by the University , Cardiff, United Kingdom 2002-11-19 -
Academic lecture

Espevik, Terje. (2002) Toll-lignende reseptor 4 - kroppens sensor for endotoxin. Norsk Biokjemisk Selskaps julemøte. , Trondheim, Norge 2002-12-16 -
Academic lecture

Espevik, Terje. (2002) HOSPATH: Towards control of septic shock induced by gram-positive bacteria: host pathogen interactions. The Euro Conference on Sepsis and Inflammation , Siena, Italy 2002-11-15 -
Academic lecture

Espevik, Terje. (2002) TLR/CD14-fluorescent protein constructs to study interactions between the receptors using dynamic confocal microscopy. HOSPATH Mid Term Evaluation of EU Project. , Trondheim, Norge 2002-09-11 -
Academic lecture

Espevik, Terje. (2002) Immune stimulating effects of alginates - relation to Toll-like receptor signalling. Forskningsparken , Oslo, Norge 2002-02-21 -
Academic lecture

Espevik, Terje. (2002) Involvement of Toll-like receptor (TLR) 2 and TLR4 in cell activation by mannuronic acid polymers. International Union of Biochemistry and Molecular Biology , Bergen, Norge 2002-05-08 -
Academic lecture

Falch, Berit H.; Espevik, Terje; Stokke, Bjørn Torger. (2002) (1->3)-beta-D-Glucan structures and immunostimulation in vitro. XXIst Internactional Carbohydrate Symposium, Cairns, Australia, July 7 - 12, 2002. , Cairns, Australia 2002-07-12 -
Academic lecture

Rokstad, Anne Mari Aukan; Strand, Berit Løkensgard; Rian, Kristin; Steinkjer, Bjørg; Ryan, Liv; Kulseng, Bård Eirik. (2002) Evaluation of different alginate microcapsules as bioreactors for 293-EBNA cells delivering the anti-angiogenic factor endostatin. 38.Biokjemiske kontaktmøte Functional genomics-the mosaics of life , Røros 2002-01-20 -
Academic lecture

Espevik, Terje. (2002) Toll-like receptors: sensors for pathogens in the innate immune system. EU-network Conference on Antigen Presentation. , Oppdal, Norge 2002-02-12 -
Academic lecture

Espevik, Terje. (2002) Involvement of Toll-like receptor (TLR)2 and TLR4 in cell activation by mannuronic acid polymers. The 7th IUBMB Conference RECEPTOR-LIGAND INTERACTIONS , Bergen, Norge 2002-05-08 -
Academic lecture

Espevik, Terje. (2002) Toll-lignende reseptorer - kroppens sensorer for patogener. Oppdalsmøtet , Oppdal, Norge 2002-04-17 -
Academic lecture

Espevik, Terje. (2002) Alginate as an immunostimulator - how does it work?. NOBIPOL-møte , Teveltunet, Meråker, Norge 2002-04-04 -
Academic lecture

Espevik, Terje. (2002) Cell distributions and functions of Toll-like receptors studied by fluorescent gene constructs. University of Massachusetts , Massachusetts, USA 2002-07-18 -
Popular scientific lecture

Espevik, Terje. (2002) Trafficing and signalling of lipopolysaccharide studied by fluorescent gene constructs. Tirsdagsmøte, IKM , Trondheim, Norge 2002-10-08 -
Popular scientific lecture

Espevik, Terje. (2002) Immunstimulating properties of alginate - an overview. R & D Gastrointestinals , Reckitt Benckiser, Hull, UK 2002-01-10 -
Poster

Nonstad, Unni; Espevik, Terje; Lien, Egil. (2002) Expression and regulation of mouse Toll-like receptor 2. 38.Biokjemiske kontaktmøte Functional genomics-the mosaics of life , Røros 2002-01-20 -
Poster

Moen, Siv H; Flo, Trude Helen; Ryan, Liv; Espevik, Terje; Sundan, Anders. (2002) Generation and functional characterization of human toll-like (TLR) 6. 38.Biokjemiske kontaktmøte Functional genomics-the mosaics of life , Røros 2002-01-20 -
Poster

Adib-Conquy, M; Moine, P; Asehnoune, K; Espevik, Terje; Miyake, K; Werts, C. (2002) TLR2-, TLR4- and TLR9-mediated TNF and IL-10 production are not similarly affected during systemic inflammation. The 7th Biennal Conference of the International Endotoxin Society , Washington, USA 2002-07-21 -
Poster

Nilsen, Nadra; Nonstad, Unni; Sundan, Anders; Espevik, Terje; Lien, Egil. (2002) Function and expression of mouse Toll-like receptor 2, a receptor for bacterial, fungal and viral components. The 7th Biennial Conference of the International Endotoxin Society. , Washington, USA 2002-07-21 -
Poster

Latz, Eicke; Visintin, A; Lien, Egil; Fitzgerald, KA; Golenbock, Douglas T.; Espevik, Terje. (2002) The LPS receptor studied by fluorescent constructs. The 7th Biennial Conference of the International Endotoxin Society , Washington, USA 2002-07-21 -
Poster

Iversen, Ann-Charlotte; Steinkjer, Bjørg; Sundan, Anders; Espevik, Terje. (2002) Selective TRAIL Expression and Utilization of Ligand Mediated Cytotoxicity in Interferon Activated Human NK Cells. The International Union of Biochemistry and Molecular Biology 7th IUBMB Conference RECEPTOR-LIGAND INTERACTIONS Molecular, Physiological and Pharmacological Aspects , Bergen, Norge 2002-05-08 -
Poster

Ryan, Liv; Flo, Trude Helen; Takeuchi, Osamu; Lien, Egil; Halaas, Øyvind; Akira, Shizuo. (2002) Involvement of TLR2 and TLR4 in activation of monocytes/macrophages by mannuronic acid polymers. The International Union of Biochemistry and Molecular Biology 7th IUBMB Conference RECEPTOR-LIGAND INTERACTIONS Molecular, Physiological and Pharmacological Aspects , Bergen, Norge 2002-05-08 -
Poster

Ryan, Liv; Flo, Trude Helen; Takeuchi, Osamu; Lien, Egil; Halaas, Øyvind; Akira, Shizuo. (2002) Involvement of TLR2 and TLR4 in activation of monocytes/macrophages by mannuronic acid polymers. 38.Biokjemiske kontaktmøte Functional genomics-the mosaics of life , Røros 2002-01-20 -
Poster

Halaas, Øyvind; Vik, Randi; Liabakk, Nina-Beate; Sundan, Anders; Espevik, Terje. (2002) Group B streptococci and interferons induce upregulation of membrane TRAIL on monocytes and cell death-dependent release of soluble TRAIL. 38.Biokjemiske kontaktmøte Functional genomics-the mosaics of life , Røros 2002-01-20 -
Poster

Espevik, Terje; Latz, Eicke; Lien, Egil; Monks, B. G.; Golenbock, Douglas T.. (2002) Cell distributions and functions of TLRs as studied by fluorescent constructs. The 7th Biennal Conference of the International Endotoxin Society , Washington, USA 2002-07-21 -

2001

Academic lecture

Strand, Berit Løkensgard; Mørch, Yrr Asbjørg; Rokstad, Anne Mari Aukan; Kulseng, Bård Eirik; Espevik, Terje; Skjåk-Bræk, Gudmund. (2001) Improved capsule properties by the use of epimerised alginate. Bioencapsulation Research Group The Ninth International Workshop in Bioencapsulation , Warsawa 2001-05-11 - 2001-05-13
Poster

Latz, Eicke; Lien, Egil; Monks, B. G.; Golenbock, D; Espevik, Terje. (2001) Cell distribution and functions of TLRs as studied by fluoroscent TLR constructs. 2nd Meeting on Septic Shock caused by Gram-positive bacteria. , Via Valentia, Italy 2001-09-22 -
Poster

Espevik, Terje. (2001) Espression and functions of TOll-like receptor 2. Experimental Biology 2001 , Orlando, Florida, USA 2001-04-04 -
Poster

Western, Karoline H; Aarvik, Tanja; Thompson, Ketih; Flo, Trude Helen; Espevik, Terje. (2001) Toll-like receptors are involved in antigen capture and presentation on MHC class II molecules to CD4+ T cells and serve as a link between innate and adaptive immunity. Keystone Symposia , Keystone, Colorado, USA 2001-01-27 -
Poster

Iversen, Ann-Charlotte; Sundan, Anders; Espevik, Terje. (2001) IFN-alpha and IFN-beta induce TRAIL-mediated NK cell cytotoxicity. Keystone Symposia Molecular Aspects of Viral Immunity , Keystone, Colorado, USA 2001-04-22 -
Poster

Western, K. H.; Thompson, Keith; Aarvak, Tanja; Flo, T. H.; Espevik, T; Bogen, Bjarne. (2001) Toll-like receptors are involved in antigen capture and presentation on MHC class II molecules to CD4+ T cells and serve as a link between innate and adaptive immunity. Meeting: Interfaces between innate and adaptive immunity (J3). , Keystone 2001-01-01 -
Academic lecture

Espevik, Terje. (2001) Properties of fluorescent TLR constructs. Department of Infectious Diseases University of Boston , Boston, USA 2001-06-20 -
Academic lecture

Espevik, Terje. (2001) Toll-like receptors: sensors for pathogens in the innate immune system. Rikshospitalet , Oslo, Norge 2001-11-03 -
Academic lecture

Espevik, Terje. (2001) Involvement of TLR-2 and TLR-4 in activation of monocytes/macrophages by mannuronic acid polymers. Boston University Medical Center , Boston, USA 2001-03-01 -
Academic lecture

Espevik, Terje. (2001) Functions and trafficking of Toll-like receptors as studied by fluorescent gene constructs. 2nd Congress on Gram Positive Sepsis , Vibo Valentia, Italia 2001-09-11 -
Academic lecture

Wang, Jacob Edward; Warris, A.; Ellingsen, Espen Alme; Jørgensen, Pål Foyn; Flo, T. H.; Espevik, T. (2001) Involvement of CD 14 and toll-like receptors in signaling by Aspergillus hypae. Surigal Infection Society-Europe , Gdansk, Poland 2001-05-31 -

2000

Poster

Iversen, Ann-Charlotte; Steinkjer, Bjørg; Liabakk, Nina-Beate; Sundan, Anders; Espevik, Terje. (2000) Interferon-beta is a potent inducer of TRAIL expression in human NK cells. IKM, NTNU 8th International TNF Congress on Tumor Necrosis Factor and Related Cytokines , Trondheim 2000-05-14 - 2000-05-18
Poster

Rokstad, Anne Mari Aukan; Kulseng, Bård Eirik; Strand, B.; Skjåk-Bræk, Gudmund; Espevik, Terje. (2000) Transplantation of Alginate Microcapsules with proliferating cells in mice: Capsular overgrowth and survival of encapsulated cells in allo-and xeno graft modells. Bioartificial organs III. Tissue Sourcing, Immunosolation and Clinical Trials. , Davos, Switzerland, 7-12 okt. 2000
Poster

Strand, Berit Løkensgard; Kulseng, Bård Eirik; Rokstad, Anne Mari Aukan; Skjåk-Bræk, Gudmund; Espevik, Terje. (2000) Identification of cells in the fibrotic reaction against transplanted encapsulated cells. Cell Transplantation Society Islets in Eilat: A combined islet basic science and transplantation meeting , Eilat 2000-09-21 - 2000-09-24
Popular scientific lecture

Strand, Berit; Holtan, Synnøve; Espevik, Terje; Skjåk-Bræk, Gudmund. (2000) Alginate AS Immibilsation materials for cells. Bioartificial Organs III , Davos, 7-12 october 2000
Popular scientific lecture

Flo, Trude Helen; Ryan, Liv; Halaas, Øyvind; Dybdal, Brit; Lien, Egil; Sundan, Anders. (2000) Detection of soluble TLR2 in human serum samples by ELISA. The 6th Conference of The International Endotoxin Society , Paris, 24-27. August, 2000
Popular scientific lecture

Halaas, Øyvind; Flo, Trude Helen; Dybdal, Brit; Torp, Sverre Helge; Lien, Egil; Sundan, Anders. (2000) Expression pattern of toll-like receptor 2. 6th Conference of the International Endotoxin Society , Paris, 24-27. August 2000
Popular scientific lecture

Flo, Trude Helen; Halaas, Øyvind; Dybdal, Brit; Torp, Sverre Helge; Lien, Egil; Miyake, Kensuke. (2000) Expression and functions of toll-like receptor 2. The 8th International TNF Congress , Trondheim, 154 - 18. mai 2000
Popular scientific lecture

Halaas, Øyvind; Vik, Randi; Ashkenazi, Avi; Espevik, Terje. (2000) LPS indueces expression of APO2 ligand/TRAIL in human monocytes and macrophages. 8th International TNF Congress CONFERENCE ON TUMOR NECROSIS FACTOR AND RELATED MOLECULES SCIENTIFIC ADVANCES AND MEDICAL APPLICATIONS , Trondheim, May 14-18, 2000
Popular scientific lecture

Flo, Trude Helen; Halaas, Øyvind; Lien, Egil; Ryan, Liv; Teti, Guiseppe; Golenbock, Douglas T.. (2000) Human toll-like receptor 2 mediates monocyte activation by listeria monocytogenes, but not by group B streptococci or lipopolysaccharide. The 36th Norwegian Biochemical Society Meeting , Geilo, 27-29 januar 2000
Poster

Flo, T.H.; Halaas, Ø.; Dybdahl, B.; Torp, S.H.; Lien, E.; Mikyake, K.. (2000) Expression and functions of Toll like receptor 2. 8th International TNF Congress , Trondheim, May 14 - 18, 2000
Poster

Liabakk, Nina-Beate; Torp, Sverre Helge; Sundan, Anders; Espevik, Terje. (2000) Detection of trail in human serum and in tissues. 8th International TNF Congress on Tumor Necrosis Factor and Related Cytokines , Trondheim, May 14-18, 2000
Poster

Halaas, Øyvind; Vik, Randi; Ashkenazi, Avi; Espevik, Terje. (2000) LPS induces expression of APO2 ligand/TRAIL in human monocytes and macrophages. 8th International Congress on Tumor Necrosis Factor and Related Cytokines. , Trondheim, May 14-18, 2000

1999

Academic lecture

Strand, Berit Løkensgard; Kulseng, Bård Eirik; Espevik, Terje; Skjåk-Bræk, Gudmund. (1999) Innkapsling av insulinproduserende celler til transplantasjon av diabetespasienter. NITO Bioingeniørdagen , Oslo 1999-04-15 - 1999-04-15
Popular scientific lecture

Ryan, Liv; Strand, Berit; Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund; Espevik, Terje. (1999) Characterisation of the toxic and cytokine inducing properties of poly-L-lysine used in alginate microcapsules. 35. Biokjemiske Kontaktmøte NBS , Rica Ishavshotel, Tromsø 21-24 januar 1999
Popular scientific lecture

Strand, Berit Løkensgard; Ryan, Liv; IntVeld, Peter; Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund; Espevik, Terje. (1999) Characterisation of the toxic and cytokine inducing properties of poly-L-lysine used in alginate microcapsules. 7th World Congress of the International Pancreas & Islet Transplant Association , Sydney, Australia, August 22 - 25, 1999
Popular scientific lecture

Espevik, Terje. (1999) Immune responses against alginate microcapsules. The Eight International Workshop on Bioencapsulation. Recent Progress in Research and Technology , Trondheim, 13 - 15. september 1999
Popular scientific lecture

Espevik, Terje. (1999) Bruk av vaksiner i kreftbehandling. , Schrødingers katt, Trondheim, oktober 1999
Popular scientific lecture

Espevik, Terje. (1999) Alginatkapsler - fra champagne produksjon til behandling av sykdommer. , Tannlegeforeningen i Trondheim, Trondheim, desember 1999
Popular scientific lecture

Rokstad, Anne Mari Aukan; Espevik, Terje; Skjåk-Bræk, Gudmund; Vadstein, Olav; Skjermo, Jorun. (1999) Alginates as adjuvant in fish vaccine against Aeromonas salmonicida. 35. Biokjemiske Kontaktmøte, NBS , Tromsø, 21-24. januar 1999
Popular scientific lecture

Strand, Berit Løkensgard; Ryan, Liv; IntVeld, Peter; Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund; Espevik, Terje. (1999) Characterisation of the toxic and cytokine inducing properties of poly-L-lysine used in alginate microcapsules. The Eight International Workshop in Bioencapsulation. Recent Progress in Research and Technology , Trondheim, Norway, September 13-15, 1999

1998

Poster

Iversen, Ann-Charlotte; Haux, Johan; Steinkjer, Bjørg; Nonstad, Unni; Egeberg, Kjartan Wøllo; Ashkenazi, Avi. (1998) Regulation of Apo-2 Ligand/Trail expression in NK cells - Involvement in NK cell mediated cytotoxicity. 7th International Tumor Necrosis Factor Congress , Hyannis 1998-05-17 - 1998-05-21
Poster

Iversen, Ann-Charlotte; Steinkjer, Bjørg; Nonstad, Unni; Egeberg, Kjartan Wøllo; Sundan, Anders; Espevik, Terje. (1998) Natural Killer cell mediated cytotoxicity involves Apo-2 Ligand/Trail. Norsk Biokjemisk Selskap Kontaktmøte nr. 34 , Lillehammer 1998-01-22 - 1998-01-25
Poster

Halaas, Øyvind; Vik, Randi; Ashkenazi, Ari; Espevik, Terje. (1998) LPS Induces Expression of Apo2ligand/TRAIL in human monocytes. The fifth conferanse of tje international endotoxin society , Santa Fe, New Mexico USA
Popular scientific lecture

Espevik, Terje. (1998) Bacterial polysaccharides as cytokine inducers: the involvement of CD14 and CD18. Vibo Valentia Seminars on Shock , Italia
Popular scientific lecture

Espevik, Terje. (1998) Dødsfaktorer i immunsystemet. Foredrag om kreftforskning , Universitetets Aula, Oslo
Popular scientific lecture

Espevik, Terje. (1998) Mekanismer for aktivering av celler i det medfødte immunsystemet. Årsmøte i Norsk immunologisk selskap , Oslo
Popular scientific lecture

Espevik, Terje. (1998) Involvement of CR3 and CR4 in the interaction of group B streptococci with cells. Norsk Biokjemisk Vintermøte , Lillehammer
Popular scientific lecture

Espevik, Terje. (1998) "Kreftforskning". Foredrag for avgangselever ved Heimdal vidr. skole , MTS
Popular scientific lecture

Espevik, Terje. (1998) Invovlement of Apo2L and FasL in NK-cell functions. Annual Meeting of the Scandinavian Society for immunology , København
Popular scientific lecture

Espevik, Terje. (1998) Oversikt over forskningsaktivitet på NK-celler og monocytter. Storlienmøte , Storlien

1997

Academic lecture

Iversen, Ann-Charlotte; Medvedev, Andrei E.; Haux, Johan; Steinkjer, Bjørg; Egeberg, Kjartan Wøllo; Lynch, David H.. (1997) Involvement of Fas and Fas Ligand in NK/LAK mediated cytotoxicity. Norsk Biokjemisk Selskap Kontaktmøte nr. 33 , Lillehammer 1997-01-23 - 1997-01-26
Academic lecture

Espevik, Terje; Kulseng, Bård Eirik. (1997) Transplantasjon av insulinproduserende celler i alginatkapsler. Invitert til Fredagsforelesning, RiT, direktesendt til Regionsy kehuset i Tromsø og sykehus i Midt-Norge , Trondheim

1996

Academic lecture

Lægreid, Astrid; Nonstad, Unni; Sundan, Anders; Espevik, Terje. (1996) Lipopolysaccharide signalling mechanism in human adenocarcinoma SW480 cells. 32. Biokjemiske kontaktmøte , Geilo
Academic lecture

Aukrust, Pål; Hestad, Kjetil; Lien, Egil; Nordøy, Ingvild; Espevik, T; Muller, Fredrik. (1996) Intravenous immunoglobulin (IVIG) administration in vivo downregulate abnormally increased activity in the tumor necrosis factor (TNF) system and increase CD4+ lymphocyte counts in HIV-infected patients. First European Conference on Experimental AIDS Research , Cannes 1996-01-01 -
Academic lecture

Muller, Fredrik; Hestad, Kjetil; Aukrust, Pål; Lien, Egil; Espevik, T; Frøland, Stig Sophus. (1996) Low expression of TNF-p75 receptor on mononuclear cells is associated with advanced immunodeficiency and high ¿viral load¿ in HIV infection. 3. International Congress on Drug Therapy in HIV Infection , Birmingham, UK 1996-01-01 -
Academic lecture

Aukrust, Pål; Hestad, Kjetil; Lien, Egil; Nordøy, Ingvild; Espevik, T; Muller, Fredrik. (1996) Downregulation of TNFa activity and increase in plasma levels of soluble Fas-antigen after intravenous immunoglobulin (IVIG) administration in vivo in HIV-infected patients are associated with increase in CD4+ lymphocyte counts. 3. International Congress on Drug Therapy in HIV Infection , Birmingham 1996-01-01 -

1995

Popular scientific lecture

Thu, Beate; Espevik, Terje; Smidsrød, Olav; Skjåk-Bræk, Gudmund. (1995) Alginate polycation microcapsules : improved functional properties by controlling the interaction between polycations and alginates. Symposium on Advances in Polysaccharides : Characteristics and Applications , [Mangler data]
Popular scientific lecture

Espevik, Terje; Kulseng, Bård Eirik; Anderson, A.; Skjåk-Bræk, Gudmund. (1995) Antibody responses to alginates in different species. Lecture at B-cell, Islets and Pancreas Transplants , [Mangler data]

1994

Poster

Arntzen, KJ; Liabakk, N-B; Jacobsen, G; Espevik, Terje; Austgulen, Rigmor. (1994) Serum levels of soluble cytokine receptors and receptor inhibitors are influenced by gestational age and delivery. NBS Norsk biokjemisk vintermøte , Beito 1994-01-15 -
Poster

Lien, E; Liabakk, N-B; Austgulen, Rigmor; Sunde, A; Sundan, A; Espevik, Terje. (1994) Characterization of receptors for tumor necrosis factor on sperm cells and in seminal plasma. NBS Norsk biokjemisk vintermøte 1994-01-15 -
Poster

Lien, E; Liabakk, N-B; Espevik, Terje; Austgulen, Rigmor. (1994) Raised levels of tumor necrosis factor receptors in human retroplacental serum. NBS Norsk biokjemisk vintermøte 1994-01-15 -
Poster

Iversen, Ann-Charlotte; Espevik, Terje; Sundan, Anders. (1994) Effect of lipopolysaccharide and poly mannuronic acid on NF-kappa B and cytokine induction in human monocytes and granulocytes. Norsk Biokjemisk Selskap Kontaktmøte nr. 30 , Beitostølen 1994-01-20 - 1994-01-23
Popular scientific lecture

Smidsrød, Olav; Skjåk-Bræk, Gudmund; Espevik, Terje. (1994) Kan alginatkuler revolusjonere diabetesbehandlingen?. Forskningskampanje - diabetesforskning , [Mangler data]
Poster

Samuelsen, Anne Berit; Paulsen, Berit Smestad; Wold, Jens Krisitian; Espevik, T; Otsuka, Hanako; Yamada, Haruki. (1994) Biologically active polysaccharides from Plantago major L. Norsk biokjemisk selskaps kontaktmøte , Beito 1994-01-01 -
Poster

Samuelsen, Anne Berit; Djahromi, Jalil M.; Paulsen, Berit Smestad; Wold, Jens Krisitian; Espevik, T; Otsuka, Hanako. (1994) Polysaccharides from large plantain (Plantago major L.). XVIIth International Carbohydrate Symposium , Ottawa, Canada 1994-01-01 -
Popular scientific lecture

Espevik, Terje; Skjåk-Bræk, Gudmund. (1994) Immunological aspects of alginates for microencapsulation. German Diabetes Society. 29th Annual Meeting , [Mangler data]

1993

Poster

Liabakk, N-B; Sunde, A; Austgulen, Rigmor; Espevik, Terje. (1993) High concentrations of soluble TNF receptor p55 in seminal plasma. NBS Norsk biokjemisk selskaps vintermøte , Beito 1993-01-15 -
Poster

Austgulen, Rigmor; Liabakk, N-B; Richardsen, W; Rahimipoor, S; Vatn, I; Espevik, Terje. (1993) Serum levels of soluble TNF receptors are influenced by gestational age and delivery in normal human pregnancy. EPG 5th Meeting of the European Placenta Group , Manchester 1993-09-15 -
Poster

Austgulen, Rigmor; Liabakk, N-B; Lien, E; Vince, G; Espevik, Terje. (1993) Occurence of soluble TNF receptors in association with normal delivery at term. NBS Norsk biokjemisk selskaps vintermøte , Beito 1993-01-15 -
Poster

Iversen, Ann-Charlotte; Naume, Bjørn; Espevik, Terje; Sundan, Anders. (1993) Analysis of IL-2, IL-7- and IL-12-induced cytokine gene expression by RT-PCR in purified NK cells. Norsk Biokjemisk Selskap Kontaktmøte nr. 29 , Beitostølen 1993-01-21 - 1993-01-24
Poster

Samuelsen, Anne Berit; Paulsen, Berit Smestad; Wold, Jens Krisitian; Espevik, T; Otsuka, Hanako; Yamada, Haruki. (1993) Polysaccharides from Plantago major - isolation, charracterization and testing of biological activity. Phytochemistry of plants used in traditional medicine , Lausanne, Sveits 1993-01-01 -

1992

Poster

Liabakk, N-B; Austgulen, Rigmor; Espevik, Terje. (1992) Soluble TNF receptors in urine and in amniotic fluid from pregnant women. NBS Norsk biokjemisk selskaps vintermøte , Beito 1992-01-15 -
Poster

Liabakk, N-B; Austgulen, Rigmor; Lien, E; Espevik, Terje. (1992) Raised levels of the 55kD TNF receptor in pregnant women and in newborns. The 4th International TNF Congress , Maastricht 1992-06-15 -
Poster

Austgulen, Rigmor; Liabakk, N-B; Lien, E; Espevik, Terje. (1992) Raised levels of the 55kD TNF receptor in serum and in urine samples from newborns and from pregnant women. The 5th International Congress of Reproductive Immunology , Rome 1992-06-15 -

1991

Poster

Liabakk, N-B; Austgulen, Rigmor; Espevik, Terje. (1991) Detection of soluble TNF receptors in urine and amniotic fluid from pregnant women. Keystone symposium on Molecular and Cellular Biology , Colorado 1991-06-15 -
Poster

Austgulen, Rigmor; Liabakk, N-B; Scott, H; Brockhaus, M; Espevik, Terje. (1991) Soluble TNF receptors in urine and in amniotic fluid from pregnant women. EPG IV Meeting of the European Placenta Group , Bern 1991-09-15 -

1986

Poster

Austgulen, Rigmor; Espevik, Terje; Nissen-Meyer, J. (1986) Human monocyte stimulation of fibroblast growth by soluble mediator(s). Scandinavian Society of Immunology , Tampere 1986-06-15 -
Poster

Espevik, Terje; Austgulen, Rigmor; Nissen-Meyer, J. (1986) Mechanism of monocyte-mediated killing of tumor cells: the monocyte cytotoxic factor (CF) identified as tumor necrosis factor (TNF). Scandinavian Society of Immunology , Tampere 1986-06-15 -

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Terje Espevik

Terje Espevik

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