2023

• Bjerkhaug, Aline; Granslo, Hildegunn Norbakken; Cavanagh, Jorunn Pauline; Høiland, Ina Isabella; Ludviksen, Judith K; Lau, Corinna; Espevik, Terje; Mollnes, Tom Eirik; Klingenberg, Claus Andreas. (2023) Dual inhibition of complement C5 and CD14 attenuates inflammation in a cord blood model. Pediatric Research.
  Academic article
• Bugge, Erlend; Wynn, Rolf; Mollnes, Tom Eirik; Reitan, Solveig Merete Klæbo; Lapid, Maria I.; Grønli, Ole Kristian. (2023) C-reactive protein levels and depression in younger and older adults - a study of 19,947 individuals. The Tromsø Study. Brain, Behavior, and Immunity - Health (BBI - Health).
  Academic article

2022

• Berven, Lise; Selvakumar, Joel Pradeepkumar; Havdal, Lise Beier; Stiansen-Sonerud, Tonje; Einvik, Gunnar; Leegaard, Truls Michael; Tjade, Trygve Olav; Michelsen, Annika Elisabet; Mollnes, Tom Eirik; Wyller, Vegard Bruun Bratholm. (2022) Inflammatory Markers, Pulmonary Function, and Clinical Symptoms in Acute COVID-19 Among Non-Hospitalized Adolescents and Young Adults. Frontiers in Immunology. volum 13:837288.
  Academic article
• Damoah, Christabel Esi; Snir, Omri; Hindberg, Kristian Dalsbø; Garred, Peter; Ludviksen, Judith K; Brækkan, Sigrid Kufaas; Morelli, Vania Maris; Mollnes, Tom Eirik; Hansen, John Bjarne; Smith, Erin N.; Brumpton, Ben Michael; Frazer, Kelly A.; Gabrielsen, Maiken Elvestad; Hveem, Kristian; Lindström, Sara; Wang, Lu; Gordon, William; Van Hylckama Vlieg, Astrid; de Andrade, Mariza; Brody, Jennifer A.; Pattee, Jack W.; Haessler, Jeffrey; Chasman, Daniel I.; Suchon, Pierre; Chen, Ming-Huei; Turman, Constance; Germain, Marine; Wiggins, Kerri L.; MacDonald, James; Armasu, Sebastian M.; Pankratz, Nathan; Jackson, Rabecca D.; Nielsen, Jonas B.; Giulianini, Franco; Puurunen, Marja K.; Ibrahim, Manal; Heckbert, Susan R.; Bammler, Theo K.; McCauley, Bryan M.; Taylor, Kent; Pankow, James S.; Reiner, Alexander P.; Deleuze, Jean-François; O'Donnell, Chris J.; Kim, Jihye; McKnight, Barbara; Kraft, Peter; Rosendaal, Frits R.; Heit, John A.; Psaty, Bruce M.. (2022) High Levels of Complement Activating Enzyme MASP-2 Are Associated With the Risk of Future Incident Venous Thromboembolism. Arteriosclerosis, Thrombosis and Vascular Biology. volum 42 (9).
  Academic article
• de Boer, Eline; Sokolova, Marina; Quach, Huy Quang; Mc Adam, Karin Ekholt; Götz, Maximilian P.; Chaban, Viktoriia; Vaage, Ingvar Jarle; Fageräng, Beatrice Linnea Christina; Woodruff, Trent M.; Garred, Peter; Nilsson, Per; Mollnes, Tom Eirik; Pischke, Soeren. (2022) Synthetic Oligodeoxynucleotide CpG Motifs Activate Human Complement through Their Backbone Structure and Induce Complement-Dependent Cytokine Release. Journal of Immunology. volum 209 (9).
  Academic article
• Emblem, Åse; Knutsen, Erik; Jørgensen, Tor Erik; Fure, Hilde; Johansen, Steinar Daae; Brekke, Ole Lars; Mollnes, Tom Eirik; Karlsen, Bård Ove. (2022) Blood Transcriptome Analysis of Septic Patients Reveals a Long Non-Coding Alu-RNA in the Complement C5a Receptor 1 Gene. Non-coding RNA. volum 8:24 (2).
  Academic article
• Gerogianni, Alexandra; Dimitrov, Jordan D.; Zarantonello, Alessandra; Poillerat, Victoria; Chonat, Satheesh; Sandholm, Kerstin; McAdam, Karin E.; Ekdahl, Kristina N.; Mollnes, Tom Eirik; Mohlin, Camilla; Roumenina, Lubka T.; Nilsson, Per. (2022) Heme Interferes With Complement Factor I-Dependent Regulation by Enhancing Alternative Pathway Activation. Frontiers in Immunology. volum 13.
  Academic article
• Habberstad, Ragnhild H; Aass, Nina Kathrine; Mollnes, Tom Eirik; Damås, Jan Kristian; Brunelli, Cinzia; Rossi, Romina; Garcia-Alonso, Elena; Kaasa, Stein; Klepstad, Pål. (2022) Inflammatory Markers and Radiotherapy Response in Patients With Painful Bone Metastases. Journal of Pain and Symptom Management. volum 64 (4).
  Academic article
• Heldal, Torbjørn Fossum; Åsberg, Anders; Ueland, Thor; Reisæter, Anna Varberg; Pischke, Søren Erik; Mollnes, Tom Eirik; Aukrust, Pål; Hartmann, Anders; Heldal, Kristian; Jenssen, Trond. (2022) Inflammation in the early phase after kidney transplantation is associated with increased long-term all-cause mortality. American Journal of Transplantation. volum 22.
  Academic article
• Jager, Neeltina M.; Venema, Leonie H.; Arykbaeva, Asel S.; Meter-Arkema, Anita H.; Ottens, Petra J.; van Kooten, Cees; Mollnes, Tom Eirik; Alwayn, Ian P. J.; Leuvenink, Henri G. D.; Pischke, Soeren. (2022) Complement Is Activated During Normothermic Machine Perfusion of Porcine and Human Discarded Kidneys. Frontiers in Immunology. volum 13.
  Academic article
• Johnson, Christina; Quach, Huy Quang; Lau, Corinna; Ekholt, Karin; Espevik, Terje; Woodruff, Trent M.; Pischke, Soeren; Mollnes, Tom Eirik; Nilsson, Per. (2022) Thrombin Differentially Modulates the Acute Inflammatory Response to Escherichia coli and Staphylococcus aureus in Human Whole Blood. Journal of Immunology. volum 208 (12).
  Academic article
• Landsem, Anne; Emblem, Åse; Lau, Corinna; Christiansen, Dorte; Gerogianni, Alexandra; Karlsen, Bård Ove; Mollnes, Tom Eirik; Nilsson, Per; Brekke, Ole Lars. (2022) Complement C3b contributes to Escherichia coli-induced platelet aggregation in human whole blood. Frontiers in Immunology. volum 13.
  Academic article
• Lupu, Ludmila; Horst, Klemens; Greven, Johannes; Mert, Ümit; Ludviksen, Judith K; Pettersen, Kristin; Lau, Corinna; Li, Yang; Palmer, Annette; Qin, Kang; Zhang, Xing; Mayer, Benjamin; van Griensven, Martijn; Huber-Lang, Markus; Hildebrand, Frank; Mollnes, Tom Eirik. (2022) Simultaneous C5 and CD14 inhibition limits inflammation and organ dysfunction in pig polytrauma. Frontiers in Immunology. volum 13.
  Academic article
• Mollnes, Tom Eirik; Storm, Benjamin; Brekke, Ole Lars; Nilsson, Per; Lambris, John D.. (2022) Application of the C3 inhibitor compstatin in a human whole blood model designed for complement research – 20 years of experience and future perspectives. Seminars in Immunology. volum 59:101604.
  Scientific translation/review
• Nguyen, Thao; Hokstad, Ingrid; Fagerland, Morten; Mollnes, Tom Eirik; Hollan, Ivana; Feinberg, Mark W.; Hjeltnes, Gunnbjørg; Eilertsen, Gro Østli; Mikkelsen, Knut; Agewall, Stefan. (2022) Antirheumatic therapy is associated with reduced complement activation in rheumatoid arthritis. PLOS ONE. volum 17 (2).
  Academic article
• Nielsen, Erik Waage; Miller, Yoav; Brekke, Ole Lars; Grond, Joost; Duong, Anh Hoang; Fure, Hilde; Ludviksen, Judith K; Pettersen, Kristin; Reubsaet, Leon; Solberg, Rigmor; Johansen, Harald Thidemann; Mollnes, Tom Eirik. (2022) A Novel Porcine Model of Ischemia-Reperfusion Injury After Cross-Clamping the Thoracic Aorta Revealed Substantial Cardiopulmonary, Thromboinflammatory and Biochemical Changes Without Effect of C1-Inhibitor Treatment. Frontiers in Immunology. volum 13.
  Academic article
• Quach, Huy Quang; Johnson, Christina; Ekholt, Karin; Islam, Rakibul; Mollnes, Tom Eirik; Nilsson, Per. (2022) Platelet-depletion of whole blood reveals that platelets potentiate the release of IL-8 from leukocytes Into plasma in a thrombin-dependent manner. Frontiers in Immunology. volum 13:865386.
  Academic article
• Soløy-Nilsen, Hedda; Nygård-Odeh, Kristin; Kristiansen, Magnhild Gangsøy; Brekke, Ole Lars; Mollnes, Tom Eirik; Reitan, Solveig Merete Klæbo; Øiesvold, Terje. (2022) Association between brain-derived neurotropic factor (BDNF), high-sensitivity C-reactive protein (hs-CRP) and psychiatric symptoms in medicated and unmedicated patients. BMC Psychiatry. volum 22 (1).
  Academic article
• Storjord, Elin; Airila-Månsson, Stella; Karlsen, Katarzyna; Madsen, Martin Ragnar Skjerve; Dahl, Jim André; Landsem, Anne; Fure, Hilde; Ludviksen, Judith K; Fjøse, Johannes Østrem; Dickey, Amy K.; Karlsen, Bård Ove; Nielsen, Erik Waage; Mollnes, Tom Eirik; Brekke, Ole Lars. (2022) Dental and Periodontal Health in Acute Intermittent Porphyria. Life. volum 12 (8).
  Academic article
• Storm, Benjamin; Ludviksen, Judith K; Christiansen, Dorte; Fure, Hilde; Pettersen, Kristin; Landsem, Anne; Nilsen, Bent Aksel; Dybwik, Knut Gustav; Braaten, Tonje; Nielsen, Erik Waage; Mollnes, Tom Eirik. (2022) Venous Air Embolism Activates Complement C3 Without Corresponding C5 Activation and Trigger Thromboinflammation in Pigs. Frontiers in Immunology. volum 13.
  Academic article
• Torp, May-Kristin; Ranheim, Trine; Schjalm, Camilla; Hjorth, Marit; Heiestad, Christina Mathisen; Dalen, Knut Tomas; Nilsson, Per; Mollnes, Tom Eirik; Pischke, Soeren; Lien, Egil; Vaage, Ingvar Jarle; Yndestad, Arne; Stensløkken, Kåre-Olav. (2022) Intracellular Complement Component 3 Attenuated Ischemia-Reperfusion Injury in the Isolated Buffer-Perfused Mouse Heart and Is Associated With Improved Metabolic Homeostasis. Frontiers in Immunology. volum 13.
  Academic article

2021

• Alme, Katinka Nordheim; Askim, Torunn; Assmus, Jörg; Mollnes, Tom Eirik; Naik, Mala; Næss, Halvor; Saltvedt, Ingvild; Ueland, Per-Magne; Ulvik, Arve; Knapskog, Anne-Brita. (2021) Investigating novel biomarkers of immune activation and modulation in the context of sedentary behaviour: a multicentre prospective ischemic stroke cohort study. BMC Neurology. volum 21 (1).
  Academic article
• Alme, Katinka Nordheim; Ulvik, Arve; Askim, Torunn; Assmus, Jörg; Mollnes, Tom Eirik; Naik, Mala; Næss, Halvor; Saltvedt, Ingvild; Ueland, Per Magne; Knapskog, Anne Brita. (2021) Neopterin and kynurenic acid as predictors of stroke recurrence and mortality: a multicentre prospective cohort study on biomarkers of inflammation measured three months after ischemic stroke. BMC Neurology. volum 21 (1).
  Academic article
• Askarian, Fatemeh; Uchiyama, Satoshi; Masson, Helen; Sørensen, Henrik Vinther; Golten, Ole; Bunæs, Anne Cathrine; Mekasha, Sophanit; Kjendseth, Åsmund Røhr; Kommedal, Eirik Garpestad; Ludviksen, Judith K; Arntzen, Magnus Øverlie; Schmidt, Benjamin; Zurich, Raymond H.; Van Sorge, Nina M.; Eijsink, Vincent G.H.; Krengel, Ute; Mollnes, Tom Eirik; Lewis, Nathan E.; Nizet, Victor; Vaaje-Kolstad, Gustav. (2021) The lytic polysaccharide monooxygenase CbpD promotes Pseudomonas aeruginosa virulence in systemic infection. Nature Communications. volum 12.
  Academic article
• Chaban, Viktoriia; Nakstad, Espen R.; Stær-Jensen, Henrik; Schjalm, Camilla; Seljeflot, Ingebjørg; Vaage, Ingvar Jarle; Lundqvist, Christofer; Saltyte Benth, Jurate; Sunde, Kjetil; Mollnes, Tom Eirik; Andersen, Geir Øystein; Pischke, Soeren. (2021) Complement activation is associated with poor outcome after out-of-hospital cardiac arrest. Resuscitation. volum 166.
  Academic article
• Coelho Medeiros, Pedro Miguel; Schjalm, Camilla; Christiansen, Dorte; Sokolova, Marina; Pischke, Soeren Erik; Würzner, Reinhard; Mollnes, Tom Eirik; Barratt-Due, Andreas. (2021) Vitamin C, Hydrocortisone, and the Combination Thereof Significantly Inhibited Two of Nine Inflammatory Markers Induced by Escherichia Coli But Not by Staphylococcus Aureus - When Incubated in Human Whole Blood. Shock. volum 57 (1).
  Academic article
• Debler, Lisa; Palmer, Annette; Braumüller, Sonja; Klohs, Bettina; Mollnes, Tom Eirik; Holzmann, Karlheinz; Huber-Lang, Markus; Halbgebauer, Rebecca. (2021) Hemorrhagic shock induces a rapid transcriptomic shift of the immune balance in leukocytes after experimental multiple injury. Mediators of Inflammation. volum 2021:6654318.
  Academic article
• Fevang, Børre; Wyller, Vegard Bruun Bratholm; Mollnes, Tom Eirik; Pedersen, Maria; Asprusten, Tarjei Tørre; Michelsen, Annika Elisabet; Ueland, Thor; Otterdal, Kari. (2021) Lasting Immunological Imprint of Primary Epstein-Barr Virus Infection With Associations to Chronic Low-Grade Inflammation and Fatigue. Frontiers in Immunology. volum 12.
  Academic article
• Garred, Peter; Tenner, A. J.; Mollnes, Tom Eirik. (2021) Therapeutic Targeting of the Complement System: From Rare Diseases to Pandemics. Pharmacological Reviews. volum 73 (2).
  Scientific translation/review
• Grimnes, Gro; Bhoelan, Soerajja; Hindberg, Kristian; Davids, Mark; Nieuwdorp, Max; Mollnes, Tom E.; Michelsen, Annika Elisabet; Ueland, Thor; Brækkan, Sigrid K.; Hansen, John-Bjarne; Tichelaar, Ynse Ieuwe Gerardus Vladimir. (2021) Impact of a Vancomycin-Induced Shift of the Gut Microbiome in a Gram-Negative Direction on Plasma Factor VIII:C Levels: Results from a Randomized Controlled Trial. Thrombosis and Haemostasis. volum 0.
  Academic article
• Holt, Margrethe Flesvig; Michelsen, Annika Elisabet; Shahini, Negar; Bjørkelund, Elisabeth; Bendz, Christina; Massey, Richard J; Schjalm, Camilla; Halvorsen, Bente; Broch, Kaspar; Ueland, Thor; Gullestad, Lars; Nilsson, Per; Aukrust, Pål; Mollnes, Tom Eirik; Louwe, Maria Cornelia. (2021) The Alternative Complement Pathway Is Activated Without a Corresponding Terminal Pathway Activation in Patients With Heart Failure. Frontiers in Immunology. volum 12.
  Academic article
• Islam, Rakibul; Islam, Mohammad Mirazul; Nilsson, Per H.; Mohlin, Camilla; Hagen, Kjersti Thorvaldsen; Paschalis, Eleftherios I.; Woods, Russell L.; Bhowmick, Sabuj Chandra; Dohlman, Claes H.; Espevik, Terje; Chodosh, James; Gonzalez-Andrades, Miguel; Mollnes, Tom Eirik. (2021) Combined blockade of complement C5 and TLR co-receptor CD14 synergistically inhibits pig-to-human corneal xenograft induced innate inflammatory responses. Acta Biomaterialia. volum 127.
  Academic article
• Langeland, Halvor Johannes Breivik; Damås, Jan Kristian; Mollnes, Tom Eirik; Ludviksen, Judith K; Ueland, Thor; Michelsen, Annika Elisabet; Løberg, Magnus; Bergum, Daniel; Nordseth, Trond; Skjærvold, Nils Kristian; Klepstad, Pål. (2021) The inflammatory response is related to circulatory failure after out-of-hospital cardiac arrest: A prospective cohort study. Resuscitation. volum 170.
  Academic article
• Macpherson, Alex; Laabei, Maisem; Ahdash, Zainab; Graewert, Melissa Ann; Birtley, James R.; Schulze, Monika-Sarah E.D.; Crennell, Susan; Robinson, Sarah A.; Holmes, Ben; Oleinikovas, Vladas; Nilsson, Per H.; Snowden, James; Ellis, Victoria; Mollnes, Tom Eirik; Deane, Charlotte M.; Svergun, Dmitri I.; Lawson, Alastair D.G.; van den Elsen, Jean. (2021) The allosteric modulation of complement c5 by knob domain peptides. eLIFE. volum 10:e63586.
  Academic article
• Nilsson, Per; Johnson, Christina; Quach, Huy Quang; Macpherson, Alex; Durrant, Oliver; Pischke, Soeren; Fure, Hilde; Landsem, Anne; Bergseth, Grete; Schjalm, Camilla; Haugaard-Kedström, Linda M.; Huber-Lang, Markus; van den Elsen, Jean; Brekke, Ole-Lars; Mollnes, Tom Eirik. (2021) A conformational change of complement C5 is required for thrombin-mediated cleavage, revealed by a novel ex vivo human whole blood model preserving full thrombin activity. Journal of Immunology. volum 207 (6).
  Academic article
• Nilsson, Per; Pettersen, Kristin; Oppermann, Martin; Skjeflo, Espen Waage; Fure, Hilde; Christiansen, Dorte; Mollnes, Tom Eirik. (2021) Quantification of Porcine Complement Activation Fragment C3a by a Neoepitope-Based Enzyme-Linked Immunosorbent Assay. Methods in molecular biology. volum 2227.
  Academic article
• Niyonzima, Nathalie; Rahman, Jubayer; Kunz, Natalie; West, Erin; Freiwald, Tilo; Desai, Jigar V.; Merle, Nicolas; Gidon, Alexandre; Sporsheim, Bjørnar; Lionakis, Michail S.; Evensen, Kristin; Lindberg, Beate; Skagen, Karolina Ryeng; Skjelland, Mona; Singh, Parul; Haug, Markus; Ruseva, Marieta M.; Kolev, Martin; Bibby, Jack; Marshall, Olivia; O’Brien, Brett; Deeks, Nigel; Afzali, Behdad; Clark, Richard J.; Woodruff, Trent M.; Pryor, Mylton; Yang, Zhi-Hong; Remaley, Alan T.; Mollnes, Tom Eirik; Hewitt, Stephen M.; Yan, Bingyu; Kazemian, Majid; Kiss, Mate G.; Binder, Christoph J.; Halvorsen, Bente; Espevik, Terje; Kemper, Claudia. (2021) Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation. Science immunology. volum 6 (66).
  Academic article
• Pethő, Ákos; Piecha, Dorothea; Mészáros, Tamás; Urbanics, Rudolf; Moore, Christoph; Canaud, Bernard; Rosivall, László; Mollnes, Tom Eirik; Steppan, Sonja; Szénási, Gábor; Szebeni, János; Dézsi, László. (2021) A porcine model of hemodialyzer reactions: roles of complement activation and rinsing back of extracorporeal blood. Renal failure. volum 43 (1).
  Academic article
• Rognes, Ingrid Nygren; Pischke, Søren Erik; Ottestad, William; Røislien, Jo; Berg, Jens Petter; Johnson, Christina; Eken, Torsten; Mollnes, Tom Eirik. (2021) Increased complement activation 3 to 6 h after trauma is a predictor of prolonged mechanical ventilation and multiple organ dysfunction syndrome: a prospective observational study. Molecular medicine (Cambridge, Mass. Print). volum 27.
  Academic article
• Sharifi, Sina; Islam, Mohammad Mirazul; Sharifi, Hannah; Islam, Rakibul; Huq, Tahmida N.; Nilsson, Per; Mollnes, Tom Eirik; Tran, Khoa D.; Patzer, Corrina; Dohlman, Claes H.; Patra, Hirak K.; Paschalis, Eleftherios I.; Gonzalez-Andrades, Miguel; Chodosh, James. (2021) Electron Beam Sterilization of Poly(Methyl Methacrylate)—Physicochemical and Biological Aspects. Macromolecular Bioscience. volum 21:2000379 (4).
  Academic article
• Sharifi, Sina; Islam, Mohammad Mirazul; Sharifi, Hannah; Islam, Rakibul; Koza, Darrell; Reyes-Ortega, Felisa; Alba-Molina, David; Nilsson, Per; Dohlman, Claes H.; Mollnes, Tom Eirik; Chodosh, James; Gonzalez-Andrades, Miguel. (2021) Tuning gelatin-based hydrogel towards bioadhesive ocular tissue engineering applications. Bioactive Materials. volum 6 (11).
  Academic article
• Skjeflo, Espen Waage; Brækkan, Sigrid Kufaas; Ludviksen, Judith K; Snir, Omri; Hindberg, Kristian; Mollnes, Tom Eirik; Hansen, John-Bjarne. (2021) Elevated plasma concentration of complement factor C5 is associated with risk of future venous thromboembolism. Blood. volum 138 (21).
  Academic article
• Skovdahl, Helene Kolstad; Gopalakrishnan, Shreya; Svendsen, Tarjei Dahl; Granlund, Atle van Beelen; Bakke, Ingunn; Ginbot, Zekarias; Thorsvik, Silje; Flatberg, Arnar; Sporsheim, Bjørnar; Ostrop, Jenny; Mollnes, Tom Eirik; Sandvik, Arne Kristian; Bruland, Torunn. (2021) Patient derived colonoids as drug testing platforms-Critical importance of oxygen concentration. Frontiers in Pharmacology. volum 12:679741.
  Academic article
• Storm, Benjamin; Christiansen, Dorte; Fure, Hilde; Ludviksen, Judith K; Lau, Corinna; Lambris, John D.; Woodruff, Trent M.; Brekke, Ole-Lars; Braaten, Tonje Bjørndal; Nielsen, Erik Waage; Mollnes, Tom Eirik. (2021) Air Bubbles Activate Complement and Trigger Hemostasis and C3-Dependent Cytokine Release Ex Vivo in Human Whole Blood. Journal of Immunology. volum 207 (11).
  Academic article
• Storm, Benjamin; Halvorsen, Per Steinar; Skulstad, Helge; Dybwik, Knut Gustav; Schjalm, Camilla; Christiansen, Dorte; Wisløff-Aase, Kristin; Fosse, Erik; Braaten, Tonje Bjørndal; Nielsen, Erik Waage; Mollnes, Tom Eirik. (2021) Open chest and pericardium facilitate transpulmonary passage of venous air emboli. Acta Anaesthesiologica Scandinavica. volum 65 (5).
  Academic article
• Sundnes, Olav; Ottestad, William Arne; Schjalm, Camilla; Lundbäck, Peter; La Cour Poulsen, Lars; Mollnes, Tom Eirik; Haraldsen, Guttorm; Eken, Torsten. (2021) Rapid systemic surge of IL-33 after severe human trauma: a prospective observational study. Molecular medicine (Cambridge, Mass. Print). volum 27:29.
  Academic article
• Thomas, Anub Mathew; Chaban, Viktoriia; Pischke, Soeren; Orrem, Hilde Lang; Bosnes, Vidar; Sunde, Kjetil; Seljeflot, Ingebjørg; Lundqvist, Christofer; Nakstad, Espen Rostrup; Andersen, Geir Øystein; Schjalm, Camilla; Mollnes, Tom Eirik; Barratt-Due, Andreas. (2021) Complement ratios C3bc/C3 and sC5b-9/C5 do not increase the sensitivity of detecting acute complement activation systemically. Molecular Immunology. volum 141.
  Academic article
• Thorgersen, Ebbe Billmann; Asvall, Jørund; Frøysnes, Ida Storhaug; Schjalm, Camilla; Larsen, Stein Gunnar; Dueland, Svein; Andersson, Yvonne; Fodstad, Øystein; Mollnes, Tom Eirik; Flatmark, Kjersti. (2021) Increased Local Inflammatory Response to MOC31PE Immunotoxin After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy. Annals of Surgical Oncology.
  Academic article
• Witczak, Bartlomiej J; Pischke, Søren E.; Reisæter, Anna V.; Midtvedt, Karsten; Ludviksen, Judith K; Heldal, Kristian; Jenssen, Trond; Hartmann, Anders; Åsberg, Anders; Mollnes, Tom E.. (2021) Elevated Terminal C5b-9 Complement Complex 10 Weeks Post Kidney Transplantation Was Associated With Reduced Long-Term Patient and Kidney Graft Survival. Frontiers in Immunology. volum 12.
  Academic article
• Würzner, Reinhard; Tedesco, Francesco; Garred, Peter; Mollnes, Tom Eirik; Truedsson, Lennart; Turner, Malcolm W.; Sommarin, Yngve; Wieslander, Jörgen; Daha, Mohamed R.. (2021) Memories of Bob Sim-Genius Complementologist and Cheerful Travel Companion. Viruses. volum 13:1068 (6).
  Letter to the editor
• Zhu, Geyunjian Harry; Azharuddin, Mohammad; Islam, Rakibul; Rahmoune, Hassan; Deb, Suryyani; Kanji, Upasona; Das, Jyotirmoy; Osterrieth, Johannes; Aulakh, Parminder; Ibrahim-Hashi, Hashi; Manchanda, Raghav; Nilsson, Per; Mollnes, Tom Eirik; Bhattacharyya, Maitreyee; Islam, Mohammad Mirazul; Hinkula, Jorma; Slater, Nigel K. H.; Patra, Hirak K.. (2021) Innate Immune Invisible Ultrasmall Gold Nanoparticles - Framework for Synthesis and Evaluation. ACS Applied Materials & Interfaces. volum 13.
  Academic article

2020

• Berg, Leif Kyrre; Goll, Rasmus; Fagerli, Erik; Ludviksen, Judith K; Fure, Hilde; Odd Sverre, Moen; Sørbye, Sveinung; Mollnes, Tom Eirik; Florholmen, Jon. (2020) Intestinal inflammatory profile shows increase in a diversity of biomarkers in irritable bowel syndrome. Scandinavian Journal of Gastroenterology. volum 55 (5).
  Academic article
• Chaban, Viktoriia; Clarke, Gerard; Skandsen, Toril; Islam, Rakibul; Einarsen, Cathrine Elisabeth; Vik, Anne; Damås, Jan Kristian; Mollnes, Tom Eirik; Håberg, Asta; Pischke, Soeren. (2020) Systemic inflammation persists the first year after mild traumatic brain injury: Results from the Prospective Trondheim Mild Traumatic Brain Injury Study. Journal of Neurotrauma. volum 37 (19).
  Academic article
• Ehrnstrøm, Birgitta; Kojen, June Frengen; Giambelluca, Miriam; Ryan, Liv; Moen, Siv Helen; Hu, Zhenyi; Yin, Hang; Mollnes, Tom Eirik; Damås, Jan Kristian; Espevik, Terje; Stenvik, Jørgen. (2020) TLR8 and complement C5 induce cytokine release and thrombin activation in human whole blood challenged with Gram-positive bacteria. Journal of Leukocyte Biology. volum 107 (4).
  Academic article
• Grinde, Dina Mikhailovna; Øverland, Torstein; Lima, Kari; Schjalm, Camilla; Mollnes, Tom Eirik; Abrahamsen, Tore G. (2020) Complement Activation in 22q11.2 Deletion Syndrome. Journal of Clinical Immunology. volum 40 (3).
  Academic article
• Holter, Jan Cato; Pischke, Soeren; de Boer, Eline; Lind, Andreas; Jenum, Synne; Holten, Aleksander Rygh; Tonby, Kristian; Barratt-Due, Andreas; Sokolova, Marina; Schjalm, Camilla; Chaban, Viktoriia; Kolderup, Heidi Anette; Tran, Trung; Tollefsrud Gjølberg, Torleif; Skeie, Linda Gail; Hesstvedt, Liv; Ormaasen, Vidar; Fevang, Børre; Austad, Cathrine; Muller, Karl Erik; Fladeby, Cathrine; Holberg-Petersen, Mona; Halvorsen, Bente; Müller, Fredrik; Aukrust, Pål; Dudman, Susanne Gjeruldsen; Ueland, Thor; Andersen, Jan Terje; Lund-Johansen, Fridtjof; Heggelund, Lars; Dyrhol-Riise, Anne Ma; Mollnes, Tom Eirik. (2020) Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients. Proceedings of the National Academy of Sciences of the United States of America. volum 117 (40).
  Academic article
• Hovland, Anders; Retterstøl, Kjetil; Mollnes, Tom Eirik; Halvorsen, Bente Evy; Aukrust, Pål; Lappegård, Knut Tore. (2020) Anti-inflammatory effects of non-statin low-density lipoprotein cholesterol-lowering drugs: an unused potential?. Scandinavian Cardiovascular Journal.
  Scientific translation/review
• Jørgensen, Marthe Jøntvedt; Holter, Jan Cato; Christensen, Erik; Schjalm, Camilla; Tonby, Kristian; Pischke, Soeren; Jenum, Synne; Skeie, Linda Gail; Nur, Sarah; Lind, Andreas; Opsand, Hanne; Enersen, Tone Burvald; Grøndahl, Ragnhild; Hermann, Anne; Dudman, Susanne Gjeruldsen; Müller, Fredrik; Ueland, Thor; Mollnes, Tom Eirik; Aukrust, Pål; Heggelund, Lars; Holten, Aleksander Rygh; Dyrhol-Riise, Anne Ma. (2020) Increased interleukin-6 and macrophage chemoattractant protein-1 are associated with respiratory failure in COVID-19. Scientific Reports. volum 10.
  Academic article
• Keshari, Ravi Shankar; Silasi, Robert; Popescu, Narcis Ioan; Regmi, Girija; Chaaban, Hala; Lambris, John D.; Lupu, Cristina; Mollnes, Tom Eirik; Lupu, Florea. (2020) CD14 inhibition improves survival and attenuates thrombo-inflammation and cardiopulmonary dysfunction in a baboon model of Escherichia coli sepsis. Journal of Thrombosis and Haemostasis. volum 19 (2).
  Academic article
• Lipcsey, Miklos; Tenhunen, Jyrki; Pischke, Soeren; Kuitunen, Anne; Flaatten, Hans; De Geer, Lina; Sjölin, Jan; Frithiof, Robert; Chew, Michelle S.; Bendel, Stepani; Kawati, Rafael; Larsson, Anders; Mollnes, Tom Eirik; Tønnessen, Tor Inge; Rubertsson, Sten. (2020) Endotoxin removal in septic shock with the Alteco LPS Adsorber was safe but showed no benefit compared to placebo in the double-blind randomized controlled trial - the Asset Study. Shock. volum 54 (2).
  Academic article
• Macpherson, Magnhild Eide; Hov, Johannes Espolin Roksund; Ueland, Thor; Dahl, Tuva Børresdatter; Kummen, Martin; Otterdal, Kari; Holm, Kristian; Berge, Rolf Kristian; Mollnes, Tom Eirik; Trøseid, Marius; Halvorsen, Bente; Aukrust, Pål; Fevang, Børre; Jørgensen, Silje Fjellgård. (2020) Gut microbiota-dependent trimethylamine N-oxide associates with inflammation in common variable immunodeficiency. Frontiers in Immunology. volum 11.
  Academic article
• Mollnes, Tom Eirik; Huber-Lang, Markus. (2020) Complement in sepsis — when science meets clinics. FEBS Letters. volum 594 (16).
  Scientific translation/review
• Niyonzima, Nathalie; Bakke, Siril Skaret; Gregersen, Ida; Holm, Sverre; Sandanger, Øystein; Orrem, Hilde Lang; Sporsheim, Bjørnar; Ryan, Liv; Kong, Xiang Yi; Dahl, Tuva Børresdatter; Skjelland, Mona; Sørensen, Kirsten; Rokstad, Anne Mari A.; Yndestad, Arne; Latz, Eicke; Gullestad, Lars; Andersen, Geir Øystein; Damås, Jan Kristian; Aukrust, Pål; Mollnes, Tom Eirik; Halvorsen, Bente; Espevik, Terje. (2020) Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis. EBioMedicine. volum 60:102985.
  Academic article
• Pedersen, Henrik; Jensen, Rasmus K.; Jensen, Jens Magnus B.; Fox, Rachel; Pedersen, Dennis V.; Olesen, Heidi G.; Hansen, Annette G.; Christiansen, Dorte; Mazarakis, Sofia M.M.; Lojek, Neal; Hansen, Pernille; Gadeberg, Trine A.F.; Zarantonello, Alessandra; Laursen, Nick S.; Mollnes, Tom Eirik; Johnson, Matthew B.; Stevens, Beth; Thiel, Steffen; Andersen, Gregers R.. (2020) A complement C3–Specific nanobody for modulation of the alternative cascade identifies the C-Terminal domain of C3b as functional in C5 convertase activity. Journal of Immunology. volum 205 (8).
  Academic article
• Shahini, Negar; Schjalm, Camilla; Nilsson, Per; Holt, Margrethe Flesvig; Øgaard, Jonas; Lien, Egil; Ahmed, Muhammad Shakil; Attramadal, Håvard; Aukrust, Pål; Yndestad, Arne; Mollnes, Tom Eirik; Louwe, Maria Cornelia. (2020) Complement component C3 and the TLR co-receptor CD14 are not involved in angiotensin II induced cardiac remodelling. Biochemical and Biophysical Research Communications - BBRC. volum 523 (4).
  Academic article
• Sharifi, Sina; Islam, Mohammad Mirazul; Sharifi, Hannah; Islam, Rakibul; Nilsson, Per; Dohlman, Claes H.; Mollnes, Tom Eirik; Paschalis, Eleftherios I.; Chodosh, James. (2020) Sputter deposition of titanium on poly(Methyl methacrylate) enhances corneal biocompatibility. Translational Vision Science & Technology. volum 9:41 (13).
  Academic article
• Storjord, Elin; Hennø, Linda Torrissen; Mollnes, Tom Eirik; Brekke, Ole-Lars. (2020) Analyse av cytokiner. Tidsskrift for Den norske legeforening. volum 140 (1).
  Article
• Storm, Benjamin; Christiansen, Dorte; Mollnes, Tom Eirik; Nielsen, Erik Waage. (2020) Avoiding ambient air in test tubes during incubations of human whole-blood minimizes complement background activation. JIM - Journal of Immunological Methods. volum 487:112876.
  Academic article
• Ueland, Nora Lamark; Ludviksen, Judith K; Hellerud, Bernt C; Mollnes, Tom Eirik; Skjeflo, Espen Waage. (2020) Choice of immunoassay to evaluate porcine cytokine levels. Veterinary Immunology and Immunopathology. volum 230:110129.
  Academic article
• Ueland, Thor; Heggelund, Lars; Lind, Andreas; Holten, Aleksander Rygh; Tonby, Kristian; Michelsen, Annika; Jenum, Synne; Jørgensen, Marthe Jøntvedt; Barratt-Due, Andreas; Skeie, Linda Gail; Nordøy, Ingvild; Fraz, Mai Sasaki Aanensen; Paulsen, Else Quist; Pischke, Soeren; Johal, Simreen Kaur; Hesstvedt, Liv; Bogen, Mette; Fevang, Børre; Halvorsen, Bente; Müller, Fredrik; Bekken, Gry Kloumann; Mollnes, Tom Eirik; Dudman, Susanne Gjeruldsen; Aukrust, Pål; Dyrhol-Riise, Anne Ma; Holter, Jan Cato. (2020) Elevated plasma sTIM-3 levels in patients with severe COVID-19. Journal of Allergy and Clinical Immunology. volum 147 (1).
  Academic article
• van den Heuvel, Lambertus P.; van de Kar, Nicole C.A.J.; Duineveld, Caroline; Sarlea, Andrei; van der Velden, Thea J.A.M.; Liebrand, Wilhelmus T. B.; van Kraaij, Sanne; Schjalm, Camilla; Bouwmeester, Romy; Wetzels, Jack F.M.; Mollnes, Tom Eirik; Volokhina, Elena B.. (2020) The complement component C5 is not responsible for the alternative pathway activity in rabbit erythrocyte hemolytic assays during eculizumab treatment. Cellular & Molecular Immunology. volum 17 (6).
  Letter to the editor
• Zhang, Jie; Song, Lihong; Pedersen, Dennis V.; Li, Anna; Lambris, John D.; Andersen, Gregers Rom; Mollnes, Tom Eirik; Ma, Ying Jie; Garred, Peter. (2020) Soluble collectin-12 mediates C3-independent docking of properdin that activates the alternative pathway of complement. eLIFE. volum 9:e60908.
  Academic article
• Østvik, Ann Elisabet; Svendsen, Tarjei Dahl; Granlund, Atle van Beelen; Doseth, Berit; Skovdahl, Helene Kolstad; Bakke, Ingunn; Thorsvik, Silje; Afroz, Wahida; Walaas, Gunnar Andreas; Mollnes, Tom Eirik; Gustafsson, Björn; Sandvik, Arne Kristian; Bruland, Torunn. (2020) Intestinal epithelial cells express immunomodulatory ISG15 during active ulcerative colitis and Crohn's disease. Journal of Crohn's and Colitis. volum 14 (7).
  Academic article

2019

• Brekke, Ole-Lars; Christiansen, Dorte; Kisserli, Aymric; Fure, Hilde; Dahl, Jim André; Donvito, Béatrice; Reveil, Brigitte; Ludviksen, Judith K; Tabary, Thierry; Mollnes, Tom Eirik; Cohen, Jacques H.M.. (2019) Key role of the number of complement receptor 1 on erythrocytes for binding of Escherichia coli to erythrocytes and for leukocyte phagocytosis and oxidative burst in human whole blood. Molecular Immunology. volum 114.
  Academic article
• Bugge, Erlend; Wynn, Rolf; Mollnes, Tom Eirik; Reitan, Solveig Merete Klæbo; Lapid, Maria I.; Grønli, Ole Kristian. (2019) Corrigendum to “Changes in cytokines during treatment of elderly, hospitalized psychiatric patients—A naturalistic study” (Psychoneuroendocrinology (2019) 108 (135–139), (S0306453019304019), (10.1016/j.psyneuen.2019.06.014)). Psychoneuroendocrinology. volum 109.
  Errata
• Bugge, Erlend; Wynn, Rolf; Mollnes, Tom Eirik; Reitan, Solveig Merete Klæbo; Lapid, Maria; Grønli, Ole Kristian. (2019) Changes in cytokines during treatment of elderly, hospitalized psychiatric patients - a naturalistic study. Psychoneuroendocrinology. volum 108.
  Academic article
• Cedzyński, Maciej; Thielens, Nicole M.; Mollnes, Tom Eirik; Vorup-Jensen, Thomas. (2019) Editorial: The Role of Complement in Health and Disease. Frontiers in Immunology. volum 10 (1869).
  Editorial
• Dahm, Anders Erik A; Jacobsen, Eva-Marie; Wik, Hilde Skuterud; Jacobsen, Anne Flem; Mollnes, Tom Eirik; Kanse, Sandip; Sandset, Per Morten. (2019) Elevated complement C3 and C4 levels are associated with postnatal pregnancy-related venous thrombosis. Thrombosis and Haemostasis. volum 119 (9).
  Academic article
• Granslo, Hildegunn Norbakken; Aarag, Elizabeth; Esaiassen, Eirin; Christophersen, Lars; Jensen, Peter Østrup; Mollnes, Tom Eirik; Moser, Claus; Flægstad, Trond; Klingenberg, Claus; Cavanagh, Jorunn Pauline. (2019) The synthetic antimicrobial peptide LTX21 induces inflammatory responses in a human whole blood model and a murine peritoneum model. APMIS - Journal of Pathologiy, Microbiology and Immunology. volum 127 (6).
  Academic article
• Gravastrand, Caroline S.; Steinkjer, Bjørg; Halvorsen, Bente; Landsem, Anne; Skjelland, Mona; Jacobsen, Eva Astrid; Woodruff, Trent M.; Lambris, John D.; Mollnes, Tom Eirik; Brekke, Ole-Lars; Espevik, Terje; Rokstad, Anne Mari. (2019) Cholesterol Crystals Induce coagulation Activation through Complement-Dependent Expression of Monocytic Tissue Factor. Journal of Immunology. volum 203 (4).
  Academic article
• Hagve, Martin Iversen; Gjessing, Petter Fosse; Hole, Mikal Jacob; Jansen, Kirsten M; Fuskevåg, Ole Martin; Mollnes, Tom Eirik; Larsen, Terje S; Irtun, Øivind. (2019) Perioperative infusion of glucagon-like peptide-1 prevents insulin resistance after surgical trauma in female pigs. Endocrinology. volum 160 (12).
  Academic article
• Hardersen, Randolf Inge; Enebakk, Terje; Christiansen, Dorte; Ludviksen, Judith K; Mollnes, Tom Eirik; Lappegård, Knut Tore; Hovland, Anders. (2019) Comparison of cytokine changes in three different lipoprotein apheresis systems in an ex vivo whole blood model. Journal of clinical apheresis.
  Academic article
• Hokstad, Ingrid; Deyab, Gia; Fagerland, Morten; Lyberg, Torstein; Hjeltnes, Gunnbjørg; Førre, Øystein Thorleiv; Agewall, Stefan; Mollnes, Tom Eirik; Hollan, Ivana. (2019) Tumor necrosis factor inhibitors are associated with reduced complement activation in spondylarthropathies: An observational study. PLOS ONE. volum 14 (7).
  Academic article
• Holt, Margrethe Flesvig; Seim, Bjørn Edvard; Øgaard, Jonas; Olsen, Maria Belland; Woldbæk, Per R; Kvitting, John Peder Escobar; Aukrust, Pål; Yndestad, Arne; Mollnes, Tom Eirik; Nilsson, Per; Louwe, Maria Cornelia; Ranheim, Trine. (2019) Selective and marked decrease of complement receptor C5aR2 in human thoracic aortic aneurysms: A dysregulation with potential inflammatory effects. Open heart. volum 6.e001098 (2).
  Academic article
• Høiland, Ina Isabella; Liang, Robin Amanda; Brækkan, Sigrid Kufaas; Pettersen, Kristin; Ludviksen, Judith K; Latysheva, Nadezhda; Snir, Omri; Ueland, Thor; Hindberg, Kristian; Mollnes, Tom Eirik; Hansen, John-Bjarne. (2019) Complement activation assessed by the plasma terminal complement complex and future risk of venous thromboembolism. Journal of Thrombosis and Haemostasis. volum 17 (6).
  Academic article
• Islam, Mohammad Mirazul; Sharifi, Roholah; Mamodaly, Shamina; Islam, Rakibul; Nahra, Daniel; Abusamra, Dina B.; Hui, Pui Chuen; Adibnia, Yashar; Goulamaly, Mehdi; Paschalis, Eleftherios I.; Cruzat, Andrea; Kong, Jing; Nilsson, Per; Argüeso, Pablo; Mollnes, Tom Eirik; Chodosh, James; Dohlman, Claes H.; Gonzalez-Andrades, Miguel. (2019) Effects of gamma radiation sterilization on the structural and biological properties of decellularized corneal xenografts. Acta Biomaterialia. volum 96.
  Academic article
• Jørgensen, Silje Fjellgård; Macpherson, Magnhild Eide; Bjørnetrø, Tonje; Holm, Kristian; Kummen, Martin; Rashidi, Azita; Michelsen, Annika; Lekva, Tove; Halvorsen, Bente; Trøseid, Marius; Mollnes, Tom Eirik; Berge, Rolf Kristian; Yndestad, Arne; Ueland, Thor; Karlsen, Tom Hemming; Aukrust, Pål; Hov, Johannes Espolin Roksund; Fevang, Børre. (2019) Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency. Scientific Reports. volum 9:167.
  Academic article
• Kozma, Gergely Tibor; Mészáros, Támas; Vashegyi, Ildikó; Fülöp, Tamás Gábor; Örfi, Erik; Dézsi, László; Rosivall, László; Bavli, Yaelle; Urbanics, Rudolf; Mollnes, Tom Eirik; Barenholz, Yechezkel; Szebeni, János. (2019) Pseudo-anaphylaxis to polyethylene glycol (PEG)-coated liposomes: Roles of anti-PEG IgM and complement activation in a porcine model of human infusion reactions. ACS Nano. volum 13 (8).
  Academic article
• Lau, Corinna; McAdam, Martin Berner; Bergseth, Grete; Grevys, Algirdas; Bruun, Jack-Ansgar; Ludviksen, Judith K; Fure, Hilde; Espevik, Terje; Moen, Anders; Andersen, Jan Terje; Mollnes, Tom Eirik. (2019) NHDL, a recombinant VL/VH hybrid antibody control for IgG2/4 antibodies. mAbs. volum 12:e1686319 (1).
  Academic article
• Liang, Robin Amanda; Høiland, Ina Isabella; Ueland, Thor; Aukrust, Pål; Snir, Omri; Hindberg, Kristian; Brækkan, Sigrid Kufaas; Garred, Peter; Mollnes, Tom Eirik; Hansen, John-Bjarne. (2019) Plasma levels of mannose-binding lectin and future risk of venous thromboembolism. Journal of Thrombosis and Haemostasis.
  Academic article
• Macpherson, Magnhild Eide; Halvorsen, Bente; Yndestad, Arne; Ueland, Thor; Mollnes, Tom Eirik; Berge, Rolf Kristian; Rashidi, Azita; Otterdal, Kari; Gregersen, Ida; Kong, Xiang Yi; Holven, Kirsten Bjørklund; Aukrust, Pål; Fevang, Børre; Jørgensen, Silje Fjellgård. (2019) Impaired HDL function amplifies systemic inflammation in common variable immunodeficiency. Scientific Reports. volum 9:9427.
  Academic article
• Mastellos, Dimitrios C.; Blom, Anna M.; Connolly, E. Sander; Daha, Mohamed R.; Geisbrecht, Brian V.; Ghebrehiwet, Berhane; Gros, Piet; Hajishengallis, George; Holers, V. Michael; Huber-Lang, Markus; Kinoshita, Taroh; Mollnes, Tom Eirik; Montgomery, Robert A.; Morgan, B. Paul; Nilsson, Bo; Pio, Ruben; Ricklin, Daniel; Risitano, Antonio; Taylor, Ronald P.; Mantovani, A; Ioannidis, John P. A.; Lambris, John D.. (2019) Author Correction: ‘Stealth’ corporate innovation: an emerging threat for therapeutic drug development (Nature Immunology, (2019), 20, 11, (1409-1413), 10.1038/s41590-019-0503-1). Nature Immunology. volum 20 (11).
  Errata
• Ottestad, William Arne; Rognes, Ingrid Nygren; Pischke, Søren; Mollnes, Tom Eirik; Andersson, Ulf; Eken, Torsten. (2019) Biphasic release of the alarmin high mobility group box 1 protein early after trauma predicts poor clinical outcome. Critical Care Medicine. volum 47 (8).
  Academic article
• Pischke, Søren; Hestenes, Siv Merete; Johansen, Harald Thidemann; Fure, Hilde; Bugge, Jan F; Espinoza, Andreas Westenvik; Skulstad, Helge; Edvardsen, Thor; Fosse, Erik; Mollnes, Tom Eirik; Halvorsen, Per Steinar; Nielsen, Erik Waage. (2019) Sepsis causes right ventricular myocardial inflammation independent of pulmonary hypertension in a porcine sepsis model. PLOS ONE. volum 14:e0218624 (6).
  Academic article
• Shahini, Negar; Ueland, Thor; Auensen, Andreas; Michelsen, Annika; Ludviksen, Judith K; Hussain, Amjad Iqbal; Pettersen, Kjell; Aakhus, Svend; Espeland, Torvald; Lunde, Ida Gjervold; Kirschfink, Michael; Nilsson, Per; Mollnes, Tom Eirik; Gullestad, Lars; Aukrust, Pål; Yndestad, Arne; Louwe, Maria Cornelia. (2019) Increased complement factor B and Bb levels are associated with mortality in patients with severe aortic stenosis. Journal of Immunology. volum 203 (7).
  Academic article
• Siljan, William Ward; Holter, Jan Cato; Michelsen, Annika; Nymo, Ståle Haugset; Lauritzen, Trine; Oppen, Kjersti; Husebye, Einar; Ueland, Thor; Mollnes, Tom Eirik; Aukrust, Pål; Heggelund, Lars. (2019) Inflammatory biomarkers are associated with aetiology and predict outcomes in community-acquired pneumonia: Results of a 5-year follow-up cohort study. ERS Monograph. volum 5 (1).
  Academic article
• Skjeflo, Espen Waage; Christiansen, Dorte; Landsem, Anne; Stenvik, Jørgen; Woodruff, T. M.; Espevik, Terje; Nielsen, Erik Waage; Mollnes, Tom Eirik. (2019) Phagocytosis of live and dead Escherichia coli and Staphylococcus aureus in human whole blood is markedly reduced by combined inhibition of C5aR1 and CD14. Molecular Immunology. volum 112.
  Academic article
• Storm, Benjamin; Christiansen, Dorte; Fure, Hilde; Nielsen, Erik Waage; Mollnes, Tom Eirik. (2019) Air bubbles induce a complement-dependent cytokine release in human whole blood in vitro and venous air embolism leads to an inflammatory response in pigs in vivo. Molecular Immunology. volum 114.
  Summary/Abstract
• Thomas, Anub Mathew; Gerogianni, Alexandra; McAdam, Martin Berner; Fløisand, Yngvar; Lau, Corinna; Espevik, Terje; Nilsson, Per; Mollnes, Tom Eirik; Barratt-Due, Andreas. (2019) Complement component C5 and TLR molecule CD14 mediate heme-induced thromboinflammation in human blood. Journal of Immunology. volum 203 (6).
  Academic article
• Thorgersen, Ebbe Billmann; Barratt-Due, Andreas; Haugaa, Håkon; Harboe, Morten; Pischke, Søren; Nilsson, Per; Mollnes, Tom Eirik. (2019) The role of complement in liver injury, regeneration, and transplantation. Hepatology. volum 70 (2).
  Scientific translation/review

2018

• Askarian, Fatemeh; Lapek Jr., John D.; Dongre, Mitesh; Tsai, Chih-Ming; Kumaraswamy, Monika; Kousha, Armin; Valderrama, J. Andrés; Ludviksen, Judith K; Cavanagh, Jorunn Pauline; Uchiyama, Satoshi; Mollnes, Tom Eirik; Gonzalez, David J.; Wai, Sun Nyunt; Victor, Nizet; Johannessen, Mona. (2018) Staphylococcus aureus Membrane-derived Vesicles Promote Bacterial Virulence and Confer Protective Immunity in Murine Infection Models. Frontiers in Microbiology. volum 9.
  Academic article
• Bugge, Erlend; Wynn, Rolf; Mollnes, Tom Eirik; Reitan, Solveig Merete Klæbo; Grønli, Ole Kristian. (2018) Cytokine profiles and diagnoses in elderly, hospitalised psychiatric patients. BMC Psychiatry. volum 18 (315).
  Academic article
• Gaarden, Torfinn Lødøen; Engedal, Knut; Saltyte Benth, Jurate; Larsen, Marianne; Lorentzen, Bernhard; Mollnes, Tom Eirik; Bjølseth, Tor Magne; Castellheim, Albert. (2018) Exploration of 27 plasma immune markers: A cross-sectional comparison of 64 old psychiatric inpatients having unipolar major depression and 18 non-depressed old persons. BMC Geriatrics. volum 18 (149).
  Academic article
• Gaya de Costa, Mariana; Poppelaars, Felix; van Kooten, Cees; Mollnes, Tom Eirik; Tedesco, Francesco; Würzner, Reinhard; Trouw, Leendert A.; Truedsson, Lennart; Daha, Mohamed R.; Roos, Anja; Seelen, Marc A.. (2018) Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population. Frontiers in Immunology. volum 9.
  Academic article
• Habberstad, Ragnhild H; Frøseth, Trude Camilla Salvesen; Aass, Nina Kathrine; Abramova, Tatiana Mikhailovna; Baas, Theo; Mørkeset, Siri Tessem; Caraceni, Augusto; Laird, Barry J; Boland, Jason W.; Rossi, Romina; Garcia-Alonso, Elena; Stensheim, Hanne; Loge, Jon Håvard; Hjermstad, Marianne Jensen; Bjerkeset, Ellen; Bye, Asta; Lund, Jo-Åsmund; Solheim, Tora Skeidsvoll; Vagnildhaug, Ola Magne; Brunelli, Cinzia; Damås, Jan Kristian; Mollnes, Tom Eirik; Kaasa, Stein; Klepstad, Pål. (2018) The Palliative Radiotherapy and Inflammation Study (PRAIS) - Protocol for a longitudinal observational multicenter study on patients with cancer induced bone pain. BMC Palliative Care. volum 17 (110).
  Academic article
• Hardersen, Randolf Inge; Enebakk, Terje; Christiansen, Dorte; Bergseth, Grete; Brekke, Ole-Lars; Mollnes, Tom Eirik; Lappegård, Knut Tore; Hovland, Anders. (2018) Granulocyte and monocyte CD11b expression during plasma separation is dependent on complement factor 5 (C5) ? an ex vivo study with blood from a C5-deficient individual. APMIS - Journal of Pathologiy, Microbiology and Immunology. volum 126 (4).
  Academic article
• Hauge, Karoline Kråkmo; Dahle, Gry; Bendz, Bjørn; Halvorsen, Per Steinar; Abdelnoor, Michael; Mollnes, Tom Eirik; Fosse, Erik. (2018) Reduced inflammatory response by transcatheter, as compared to surgical aortic valve replacement. Scandinavian Cardiovascular Journal. volum 52 (1).
  Academic article
• Høiland, Ina Isabella; Liang, Robin Amanda; Hindberg, Kristian; Latysheva, Nadezhda; Brekke, Ole-Lars; Mollnes, Tom Eirik; Hansen, John-Bjarne. (2018) Associations between complement pathways activity, mannose-binding lectin, and odds of unprovoked venous thromboembolism. Thrombosis Research. volum 169.
  Academic article
• Kleveland, Ola; Ueland, Thor; Kunszt, Gabor; Bratlie, Marte; Yndestad, Arne; Broch, Kaspar; Holte, Espen; Ryan, Liv; Amundsen, Brage H.; Bendz, Bjørn; Aakhus, Svend; Espevik, Terje; Halvorsen, Bente; Mollnes, Tom Eirik; Wiseth, Rune; Gullestad, Lars; Aukrust, Pål; Damås, Jan Kristian. (2018) Interleukin-6 receptor inhibition with tocilizumab induces a selective and substantial increase in plasma IP-10 and MIP-1β in non-ST-elevation myocardial infarction. International Journal of Cardiology. volum 271.
  Academic article
• Landsem, Anne; Fure, Hilde; Ludviksen, Judith K; Christiansen, Dorte; Lau, Corinna; Mathisen, Monica Dammen; Bergseth, Grete; Nymo, Stig Haugset; Lappegård, Knut Tore; Woodruff, T. M.; Espevik, Terje; Mollnes, Tom Eirik; Brekke, Ole-Lars. (2018) Complement component 5 does not interfere with physiological hemostasis but is essential for Escherichia coli-induced coagulation accompanied by Toll-like receptor 4. Clinical and Experimental Immunology.
  Academic article
• Langeland, Halvor; Bergum, Daniel; Løberg, Magnus; Bjørnstad, Knut; Damås, Jan Kristian; Mollnes, Tom Eirik; Skjaervold, Nils Kristian; Klepstad, Pål. (2018) Transitions Between Circulatory States After Out-of-Hospital Cardiac Arrest: Protocol for an Observational, Prospective Cohort Study. JMIR Research Protocols. volum 7 (1).
  Academic article
• Nielsen, Erik Waage; Storm, Benjamin; Christiansen, Dorte; Mollnes, Tom Eirik. (2018) Venous air embolism-indiced coagulation prevented by complement C5 inhibition. Molecular Immunology. volum 102.
  Summary/Abstract
• Orrem, Hilde Lang; Nilsson, Per; Pischke, Søren Erik; Grindheim, Guro; Garred, Peter; Seljeflot, Ingebjørg; Husebye, Trygve Guttorm; Aukrust, Pål; Yndestad, Arne; Andersen, Geir Øystein; Barratt-Due, Andreas; Mollnes, Tom Eirik. (2018) Acute heart failure following myocardial infarction: complement activation correlates with the severity of heart failure in patients developing cardiogenic shock. ESC Heart Failure. volum 5 (3).
  Academic article
• Orrem, Hilde Lang; Nilsson, Per; Pischke, Søren Erik; Kleveland, Ola; Yndestad, Arne; Ekholt, Karin; Damås, Jan Kristian; Espevik, Terje; Bendz, Bjørn; Halvorsen, Bente; Gregersen, Ida; Wiseth, Rune; Andersen, Geir Øystein; Ueland, Thor; Gullestad, Lars; Aukrust, Pål; Barratt-Due, Andreas; Mollnes, Tom Eirik. (2018) IL-6 receptor inhibition by tocilizumab attenuated expression of C5a receptor 1 and 2 in non-ST-elevation myocardial infarction. Frontiers in Immunology. volum 9.
  Academic article
• Orrem, Hilde Lang; Shetelig, Christian; Ueland, Thor; Limalanathan, Shanmuganathan; Nilsson, Per; Husebye, Trygve Guttorm; Aukrust, Pål; Seljeflot, Ingebjørg; HOFFMANN, PAVEL; Eritsland, Jan; Mollnes, Tom Eirik; Andersen, Geir Øystein; Yndestad, Arne. (2018) Soluble IL-1 receptor 2 is associated with left ventricular remodelling in patients with ST-elevation myocardial infarction. International Journal of Cardiology. volum 268.
  Academic article
• Quist-Paulsen, Else; Aukrust, Pål; Kran, Anne-Marte Bakken; Dunlop, Oona Borghild; Ormaasen, Vidar; Stiksrud, Birgitte; Midttun, Øivind; Ueland, Thor; Ueland, Per Magne; Mollnes, Tom Eirik; Dyrhol-Riise, Anne Ma. (2018) High neopterin and IP-10 levels in cerebrospinal fluid are associated with neurotoxic tryptophan metabolites in acute central nervous system infections. Journal of Neuroinflammation. volum 15 (327).
  Academic article
• Siljan, William Ward; Holter, Jan Cato; Michelsen, Annika Elisabet; Nymo, Ståle Haugset; Norseth, Jon; Husebye, Einar; Lauritzen, Trine; Ueland, Thor; Mollnes, Tom Eirik; Aukrust, Pål; Heggelund, Lars. (2018) Procalcitonin has wider applicability in community-acquired pneumonia than other biomarkers. European Respiratory Journal.
  Summary/Abstract
• Siljan, William Ward; Holter, Jan Cato; Nymo, Ståle Haugset; Husebye, Einar; Ueland, Thor; Skattum, Lillemor; Bosnes, Vidar; Garred, Peter; Frøland, Stig Sophus; Mollnes, Tom Eirik; Aukrust, Pål; Heggelund, Lars. (2018) Low levels of immunoglobulins and mannose-binding lectin are not associated with etiology, severity, or outcome in community-acquired pneumonia. Open Forum Infectious Diseases. volum 5 (2).
  Academic article
• Skaare, Helga; Svensson, My Hanna Sofia; Jenssen, Trond Geir; Åsberg, Anders; Schmidt, Erik Berg; Chandra, Anupam; Ueland, Thor; Mollnes, Tom Eirik; Hartmann, Anders; Eide, Ivar Anders. (2018) Plasma n-6 Polyunsaturated Fatty Acid Levels and Survival in Renal Transplantation. Journal of renal nutrition. volum 28 (5).
  Academic article
• Skjeflo, Espen Waage; Christiansen, Dorte; Fure, Hilde; Ludviksen, Judith K; Woodruff, Trent M.; Espevik, Terje; Nielsen, Erik Waage; Brekke, Ole-Lars; Mollnes, Tom Eirik. (2018) Staphylococcus aureus-induced complement activation promotes tissue factor-mediated coagulation. Journal of Thrombosis and Haemostasis. volum 16 (5).
  Academic article
• Skovdahl, Helene Kolstad; Damås, Jan Kristian; Granlund, Atle van Beelen; Østvik, Ann Elisabet; Doseth, Berit; Bruland, Torunn; Mollnes, Tom Eirik; Sandvik, Arne Kristian. (2018) C-C Motif Ligand 20 (CCL20) and C-C Motif Chemokine Receptor 6 (CCR6) in Human Peripheral Blood Mononuclear Cells: Dysregulated in Ulcerative Colitis and a Potential Role for CCL20 in IL-1β Release. International Journal of Molecular Sciences. volum 19 (10).
  Academic article
• Thomas, Anub Mathew; Schjalm, Camilla; Nilsson, Per; Lindenskov, Paal Helge H.; Rørtveit, Runa; Solberg, Rønnaug; Saugstad, Ola Didrik; Berglund, Magnus M.; Strömberg, Patrik; Lau, Corinna; Espevik, Terje; Jansen, Johan Høgset; Castellheim, Albert; Mollnes, Tom Eirik; Barratt-Due, Andreas. (2018) Combined Inhibition of C5 and CD14 Attenuates Systemic Inflammation in a Piglet Model of Meconium Aspiration Syndrome. Neonatology. volum 113 (4).
  Academic article
• Wendelbo, Øystein; Opheim, Elin Netland; Hervig, Tor; Lunde, Turid Helen Felli; Bruserud, Øystein; Mollnes, Tom Eirik; Reikvam, Håkon. (2018) Cytokine profiling and post-transfusion haemoglobin increment in patients with haematological diseases. Vox Sanguinis. volum 113.
  Academic article
• Wolf-Grosse, Susann; Mollnes, Tom Eirik; Ali, Syed; Stenvik, Jørgen; Nilsen, Asbjørn Magne. (2018) Iron oxide nanoparticles enhance Toll-like receptor-induced cytokines in a particle size- and actin-dependent manner in human blood. Nanomedicine. volum 13 (14).
  Academic article
• Østvik, Ann Elisabet; Svendsen, Tarjei Dahl; Granlund, Atle van Beelen; Doseth, Berit; Bakke, Ingunn; Thorsvik, Silje; Afroz, Wahida; Skovdahl, Helene Kolstad; Mollnes, Tom Eirik; Gustafsson, Björn; Sandvik, Arne Kristian; Bruland, Torunn. (2018) Tu1753 - type 1 Interferon Signaling in Intestinal Epithelial Cells During Active Inflammatory Bowel Disease. Gastroenterology. volum 154 (6).
  Summary/Abstract

2017

• Bakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Pilely, Katrine; Ryan, Liv; Skjelland, Mona; Garred, Peter; Aukrust, Pål; Halvorsen, Bente; Latz, Eicke; Damås, Jan Kristian; Mollnes, Tom Eirik; Espevik, Terje. (2017) Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation. Journal of Immunology. volum 199 (8).
  Academic article
• Barratt-Due, Andreas; Pischke, Søren Erik; Nilsson, Per; Espevik, Terje; Mollnes, Tom Eirik. (2017) Dual inhibition of complement and Toll-like receptors as a novel approach to treat inflammatory diseases-C3 or C5 emerge together with CD14 as promising targets. Journal of Leukocyte Biology. volum 101 (1).
  Scientific translation/review
• Eide, Ivar Anders; Åsberg, Anders; Svensson, My Hanna Sofia; Ueland, Thor; Mollnes, Tom Eirik; Hartmann, Anders; Bjerve, Kristian S; Michelsen, Annika; Aukrust, Pål; Schmidt, EB; Christensen, JH; Jenssen, Trond Geir. (2017) Plasma Levels of Marine n-3 Fatty Acids Are Inversely Correlated With Proinflammatory Markers sTNFR1 and IL-6 in Renal Transplant Recipients. Journal of renal nutrition. volum 27 (3).
  Academic article
• Genster, Ninette; Østrup, Olga; Schjalm, Camilla; Mollnes, Tom Eirik; Cowland, Jack B.; Garred, Peter. (2017) Ficolins do not alter host immune responses to lipopolysaccharide-induced inflammation in vivo. Scientific Reports. volum 7 (1).
  Academic article
• Gravastrand, Caroline; Hamad, Shamal; Fure, Hilde; Steinkjer, Bjørg; Ryan, Liv; Oberholzer, José; Lambris, John D.; Lacík, Igor; Mollnes, Tom Eirik; Espevik, Terje; Brekke, Ole-Lars; Rokstad, Anne Mari. (2017) Alginate microbeads are coagulation compatible, while alginate microcapsules activate coagulation secondary to complement or directly through FXII. Acta Biomaterialia. volum 58.
  Academic article
• Gustavsen, Alice; Skattum, Lillemor; Bergseth, Grete; Lorentzen, Bjørg; Fløisand, Yngvar; Bosnes, Vidar; Mollnes, Tom Eirik; Barratt-Due, Andreas. (2017) Effect on mother and child of eculizumab given before caesarean section in a patient with severe antiphospholipid syndrome. Medicine. volum 96 (11).
  Academic article
• Harboe, Morten; Johnson, Christina; Nymo, Stig Haugset; Ekholt, Karin; Schjalm, Camilla; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Hellerud, Bernt C; Ekdahl, Kristina Nilsson; Mollnes, Tom Eirik; Nilsson, Per. (2017) Properdin binding to complement activating surfaces depends on initial C3b deposition. Proceedings of the National Academy of Sciences of the United States of America. volum 114 (4).
  Academic article
• Hellerud, Bernt C; Orrem, Hilde Lang; Dybwik, Knut Gustav; Pischke, Søren Erik; Barratt-Due, Andreas; Castellheim, Albert; Fure, Hilde; Bergseth, Grete; Christiansen, Dorte; Nunn, Miles A.; Espevik, Terje; Lau, Corinna; Brandtzæg, Petter; Nielsen, Erik Waage; Mollnes, Tom Eirik. (2017) Combined inhibition of C5 and CD14 efficiently attenuated the inflammatory response in a porcine model of meningococcal sepsis. Journal of Intensive Care. volum 5:21.
  Academic article
• Hennø, Linda Torrissen; Storjord, Elin; Christiansen, Dorte; Bergseth, Grete; Ludviksen, Judith K; Fure, Hilde; Barene, Svein; Nielsen, Erik Waage; Mollnes, Tom Eirik; Brekke, Ole Lars. (2017) Effect of the anticoagulant, storage time and temperature of blood samples on the concentrations of 27 multiplex assayed cytokines ? Consequences for defining reference values in healthy humans. Cytokine. volum 97.
  Academic article
• Keshari, Ravi Shankar; Silasi, Robert; Popescu, Narcis Ioan; Patel, Maulin Mukeshchandra; Chaaban, Hala; Lupu, Cristina; Coggeshall, K. Mark; Mollnes, Tom Eirik; Demarco, Steven J.; Lupu, Florea. (2017) Inhibition of complement C5 protects against organ failure and reduces mortality in a baboon model of Escherichia coli sepsis. Proceedings of the National Academy of Sciences of the United States of America. volum 114 (31).
  Academic article
• Nilsson, Per; Thomas, Anub Mathew; Bergseth, Grete; Gustavsen, Alice; Volokhina, Elena B.; van den Heuvel, Lambertus P.; Barratt-Due, Andreas; Mollnes, Tom Eirik. (2017) Eculizumab-C5 complexes express a C5a neoepitope in vivo: Consequences for interpretation of patient complement analyses. Molecular Immunology. volum 89.
  Academic article
• Niyonzima, Nathalie; Halvorsen, Bente; Sporsheim, Bjørnar; Garred, Peter; Aukrust, Pål; Mollnes, Tom Eirik; Espevik, Terje. (2017) Complement activation by cholesterol crystals triggers a subsequent cytokine response. Molecular Immunology. volum 84.
  Academic article
• Paunas, Theodora Ioana; Finne, Kenneth; Leh, Sabine Maria; Marti, Hans-Peter; Mollnes, Tom Eirik; Berven, Frode; Vikse, Bjørn Egil. (2017) Glomerular abundance of complement proteins characterized by proteomic analysis of laser-captured microdissected glomeruli associates with progressive disease in IgA nephropathy. Clinical Proteomics. volum 14 (30).
  Academic article
• Pischke, Søren Erik; Gustavsen, Alice; Orrem, Hilde Lang; Egge, Kjetil Hagene; Courivaud, Fredric A A; Fontenelle, Hugues; Despont, Alain; Bongoni, Anjan K.; Rieben, Robert; Tønnessen, Tor Inge; Nunn, Miles A.; Scott, Helge; Skulstad, Helge; Barratt-Due, Andreas; Mollnes, Tom Eirik. (2017) Complement factor 5 blockade reduces porcine myocardial infarction size and improves immediate cardiac function. Basic Research in Cardiology. volum 112:20 (3).
  Academic article
• Ricklin, Daniel; Barratt-Due, Andreas; Mollnes, Tom Eirik. (2017) Complement in clinical medicine: Clinical trials, case reports and therapy monitoring. Molecular Immunology. volum 89.
  Scientific translation/review
• Shahini, Negar; Michelsen, Annika; Nilsson, Per; Ekholt, Karin; Gullestad, Lars; Broch, Kaspar; Dahl, Christen Peder; Aukrust, Pål; Ueland, Thor; Mollnes, Tom Eirik; Yndestad, Arne; Louwe, Maria Cornelia. (2017) The alternative complement pathway is dysregulated in patients with chronic heart failure. Scientific Reports. volum 7.
  Academic article
• Shields, Kelly J.; Mollnes, Tom Eirik; Eidet, Jon Roger; Mikkelsen, Knut; Almdahl, Sven Martin; Bottazzi, Barbara; Lyberg, Torstein; Manzi, Susan; Ahearn, Joseph M; Hollan, Ivana. (2017) Plasma complement and vascular complement deposition in patients with coronary artery disease with and without inflammatory rheumatic diseases. PLOS ONE. volum 12 (3).
  Academic article
• Siljan, William Ward; Holter, Jan Cato; Nymo, Ståle Haugset; Husebye, Einar; Ueland, Thor; Aukrust, Pål; Mollnes, Tom Eirik; Heggelund, Lars. (2017) Cytokine responses, microbial aetiology and short-term outcome in community-acquired pneumonia. European Journal of Clinical Investigation. volum 48 (1).
  Academic article
• Smedbråten, Julia; Sagedal, Solbjørg; Åsberg, Anders; Hartmann, Anders; Rollag, Halvor; Mjøen, Geir; Fagerland, Morten; Hansen, S. W. K.; Mollnes, Tom Eirik; Thiel, S.. (2017) Collectin liver 1 and collectin kidney 1 of the lectin complement pathway are associated with mortality after kidney transplantation. American Journal of Transplantation. volum 17 (1).
  Academic article
• Storjord, Elin; Dahl, Jim André; Landsem, Anne; Fure, Hilde; Ludviksen, Judith K; Goldbeck-Wood, Sandy; Karlsen, Bård Ove; Berg, Kristin Sandal; Mollnes, Tom Eirik; Nielsen, Erik Waage; Brekke, Ole Lars. (2017) Systemic inflammation in acute intermittent porphyria:a case–control study. Clinical and Experimental Immunology. volum 187 (3).
  Academic article
• Wibroe, Peter Popp; Anselmo, Aaron C; Nilsson, Per; Sarode, Apoorva; Gupta, Vivek; Urbanics, Rudolf; Szebeni, Janos; Hunter, Alan Christy; Mitragotri, Samir; Mollnes, Tom Eirik; Moghimi, Seyed Moein. (2017) Bypassing adverse injection reactions to nanoparticles through shape modification and attachment to erythrocytes. Nature Nanotechnology. volum 12 (6).
  Academic article
• Wolf-Grosse, Susann; Rokstad, Anne Mari; Ali, Syed; Lambris, JD; Mollnes, Tom Eirik; Nilsen, Asbjørn Magne; Stenvik, Jørgen. (2017) Iron oxide nanoparticles induce cytokine secretion in a complement-dependent manner in a human whole blood model. International Journal of Nanomedicine. volum 12.
  Academic article
• Wyller, Vegard Bruun Bratholm; Nguyen, Chinh Bkrong Thi Thuy; Ludviksen, Judith K; Mollnes, Tom Eirik. (2017) Transforming growth factor beta (TGF‑β)in adolescent chronic fatigue syndrome. Journal of Translational Medicine. volum 15 (1).
  Academic article

2016

• Aresvik, Dina; Lima, Kari; Øverland, Torstein; Mollnes, Tom Eirik; Abrahamsen, Tore G. (2016) Increased Levels of Interferon-Inducible Protein 10 (IP-10) in 22q11.2 Deletion Syndrome. Scandinavian Journal of Immunology. volum 83 (3).
  Academic article
• Barratt-Due, Andreas; Fløisand, Yngvar; Lang, Hilde Elisabeth; Kvam, Ann Kristin; Holme, Pål Andre; Bergseth, Grete; Tjønnfjord, Geir Erland; Mollnes, Tom Eirik. (2016) Complement activation is a crucial pathogenic factor in catastrophic antiphospholipid syndrome. Rheumatology.
  Academic article
• Garabet, Lamya Samir Noori; Gilboe, Inge-Margrethe; Mowinckel, Marie-Christine; Jacobsen, Anne Flem; Mollnes, Tom Eirik; Sandset, Per Morten; Jacobsen, Eva-Marie. (2016) Antiphospholipid antibodies are associated with low levels of complement C3 and C4 in patients with systemic Lupus Erythematosus. Scandinavian Journal of Immunology. volum 84 (2).
  Academic article
• Gustavsen, Alice; Nymo, Stig Haugset; Landsem, Anne; Christiansen, Dorte; Ryan, Liv; Husebye, Harald; Lau, Corinna; Pischke, Søren Erik; Lambris, John D.; Espevik, Terje; Mollnes, Tom Eirik. (2016) Combined inhibition of complement and CD14 attenuates bacteria-induced inflammation in human whole blood more efficiently than antagonizing the toll-like receptor 4-MD2 complex. Journal of Infectious Diseases. volum 214 (1).
  Academic article
• Hestad, Knut; Engedal, Knut; Whist, Jon Elling; Aukrust, Pål; Farup, Per Grønaas; Mollnes, Tom Eirik; Ueland, Thor. (2016) Patients with depression display cytokine levels in serum and cerebrospinal fluid similar to patients with diffuse neurological symptoms without a defined diagnosis. Neuropsychiatric Disease and Treatment. volum 12.
  Academic article
• Huang, Shan; Engberg, Anna E.; Jonsson, Nina; Sandholm, Kerstin; Nicholls, Ian A; Mollnes, Tom Eirik; Fromell, Karin; Nilsson, Bo; Ekdahl, Kristina Nilsson. (2016) Reciprocal relationship between contact and complement system activation on artificial polymers exposed to whole human blood. Biomaterials. volum 77.
  Academic article
• Jørgensen, Silje Fjellgård; Trøseid, Marius; Kummen, Martin; Anmarkrud, Jarl Andreas; Michelsen, Annika; Osnes, Liv T. N.; Holm, Kristian; Høivik, Marte; Rashidi, Azita; Dahl, Christen Peder; Vesterhus, Mette; Halvorsen, Bente; Mollnes, Tom Eirik; Berge, Rolf Kristian; Moum, Bjørn; Lundin, Knut Erik Aslaksen; Fevang, Børre; Ueland, Thor; Karlsen, Tom Hemming; Aukrust, Pål; Hov, Johannes Espolin Roksund. (2016) Altered gut microbiota profile in common variable immunodeficiency associates with levels of lipopolysaccharide and markers of systemic immune activation. Mucosal Immunology.
  Academic article
• Landsem, Anne; Fure, Hilde; Mollnes, Tom Eirik; Nielsen, Erik Waage; Brekke, Ole Lars. (2016) C1-inhibitor efficiently delays clot development in normal human whole blood and inhibits Escherichia coli-induced coagulation measured by thromboelastometry. Thrombosis Research. volum 143.
  Academic article
• Lappegård, Knut Tore; Enebakk, Terje; Thunhaug, Hilde; Ludviksen, Judith K; Mollnes, Tom Eirik; Hovland, Anders. (2016) LDL apheresis activates the complement system and the cytokine network, whereas PCSK9 inhibition with evolocumab induces no inflammatory response. Journal of Clinical Lipidology. volum 10 (6).
  Academic article
• Meroni, P.L.; Macor, P.; Durigutto, P; De Maso, L; Gerosa, M; Ferraresso, M; Borghi, MO; Mollnes, Tom Eirik; Tedesco, F.. (2016) Complement activation in antiphospholipid syndrome and its inhibition to prevent rethrombosis after arterial surgery. Blood.
  Letter to the editor
• Niyonzima, Nathalie; Freeley, Simon; Arbore, Giuseppina; Le Friec, Gaelle; Lappegård, Knut Tore; Mollnes, Tom Eirik; Kemper, Claudia; Espevik, Terje. (2016) The intracellular C5 system is critical to DAMP sensing and cellular responses in human monocytes. Immunobiology.
  Summary/Abstract
• Nymo, Stig Haugset; Gustavsen, Alice; Nilsson, Per; Lau, Corinna; Espevik, Terje; Mollnes, Tom Eirik. (2016) Human endothelial cell activation by Escherichia coli and staphylococcus aureus is mediated by TNF and IL-1β secondarily to activation of C5 and CD14 in whole blood. Journal of Immunology. volum 196 (5).
  Academic article
• Otterdal, Kari; Portillo, Aránzazu; Astrup, Elisabeth; Ludviksen, Judith K; Davi, Giovanni; Holm, Sverre; Santilli, Francesca; Vitale, Giustina; Raoult, Didier; Olano, Juan P.; Schjalm, Camilla; Halvorsen, Bente; Oteo, José A.; Mollnes, Tom Eirik; Aukrust, Pål; Nilsson, Per. (2016) High serum CXCL10 in Rickettsia conorii infection is endothelial cell mediated subsequent to whole blood activation. Cytokine. volum 83.
  Academic article
• Otterdal, Kari; Portillo, Aránzazu; Astrup, Elisabeth; Ludviksen, Judith K; Schjalm, Camilla; Raoult, Didier; Olano, Juan Pablo; Halvorsen, Bente; Oteo Revuelta, José Antonio; Aukrust, Pål; Mollnes, Tom Eirik; Nilsson, Per. (2016) Rickettsia conorii is a potent complement activator in vivo and combined inhibition of complement and CD14 is required for attenuation of the cytokine response ex vivo. Clinical Microbiology and Infection (CMI). volum 22 (8).
  Academic article
• Pilely, Katrine; Rosbjerg, Anne; Genster, Ninette; Gál, Peter; Pál, Gábor; Halvorsen, Bente; Holm, Sverre; Aukrust, Pål; Bakke, Siril Skaret; Sporsheim, Bjørnar; Nervik, Ingunn; Niyonzima, Nathalie; Bartels, Emil D.; Stahl, Gregory L.; Mollnes, Tom Eirik; Espevik, Terje; Garred, Peter. (2016) Cholesterol crystals activate the lectin complement pathway via ficolin-2 and mannose-binding lectin: Implications for the progression of atherosclerosis. Journal of Immunology. volum 196 (12).
  Academic article
• Seip, Knut Fredrik; Evjenth, Bjørg; Hovland, Anders; Dybwik, Knut Gustav; Johansen, Harald Thidemann; Fure, Hilde; Mollnes, Tom Eirik; Nielsen, Erik Waage. (2016) Bradykinin-Induced Shock Increase Exhaled Nitric Oxide, Complement Activation and Cytokine Production in Pigs. Journal of Cardiology & Clinical Research. volum 4 (2).
  Academic article
• Siljan, William; Holter, Jan Cato; Nymo, Ståle Haugset; Schjalm, Camilla; Müller, Fredrik; Jenum, Pål; Husebye, Einar; Ueland, Thor; Aukrust, Pål; Mollnes, Tom Eirik; Heggelund, Lars. (2016) Circulating cell-free DNA is elevated in community-acquired bacterial pneumonia and predicts short-term outcome. Journal of Infection. volum 73 (4).
  Letter to the editor
• SMEDBRÅTEN, Julia; Mjøen, Geir; Hartmann, Anders; Åsberg, Anders; Rollag, Halvor; Mollnes, Tom Eirik; Sandvik, Leiv; Fagerland, Morten; Thiel, Steffen; Sagedal, Solbjørg. (2016) Low level of MAp44, an inhibitor of the lectin complement pathway, and long-term graft and patient survival; a cohort study of 382 kidney recipients. BMC Nephrology. volum 17 (1).
  Academic article
• Stiksrud, Birgitte; Lorvik, Kristina Berg; Kvale, Dag; Mollnes, Tom Eirik; Ueland, Per Magne; Trøseid, Marius; Tasken, Kjetil; Dyrhol-Riise, Anne Ma. (2016) Plasma IP-10 is increased in immunological nonresponders and associated with activated regulatory T cells and persisting low CD4 counts. Journal of Acquired Immune Deficiency Syndromes. volum 73 (2).
  Academic article
• Stylianou, Eva; Ueland, Thor; Borchsenius, Fredrik; Michelsen, Annika; Øvstebø, Reidun; Mollnes, Tom Eirik; Skjønsberg, Ole Henning; Aukrust, Pål. (2016) Specific allergen immunotherapy: Effect on IgE, IgG4 and chemokines in patients with allergic rhinitis. Scandinavian Journal of Clinical and Laboratory Investigation. volum 76 (2).
  Academic article
• Wyller, Vegard Bruun; Reme, Silje; Mollnes, Tom Eirik. (2016) Kronisk utmattelsessyndrom/myalgisk encefalopati - sykdomsmekanismer, diagnostikk og behandling. Fysioterapeuten. volum 83 (2).
  Chronicle
• Ørning, Mathias Pontus; Hoem, Kine Samset; Coron, Abba Elizabeth; Skjåk-Bræk, Gudmund; Mollnes, Tom Eirik; Brekke, Ole Lars; Espevik, Terje; Rokstad, Anne Mari. (2016) Alginate microsphere compositions dictate different mechanisms of complement activation with consequences for cytokine release and leukocyte activation. Journal of Controlled Release. volum 229.
  Academic article

2015

• Hallstensen, Randi; Bergseth, Grete; Foss, Stian; Jæger, Steinar; Gedde-Dahl, Thobias; Holt, jan; Christiansen, Dorte; Lau, Corinna; Brekke, Ole Lars; Armstrong, Elina; Stefanovic, Vedran; Andersen, Jan Terje; Sandlie, Inger; Mollnes, Tom Eirik. (2015) Eculizumab treatment during pregnancy does not affect the complement system activity of the newborn. Immunobiology. volum 220 (4).
  Academic article
• Asprusten, Tarjei Tørre; Fagermoen, Frode Even; Sulheim, Dag; Skovlund, Eva; Sørensen, Øystein; Mollnes, Tom Eirik; Wyller, Vegard Bruun. (2015) Study findings challenge the content validity of the Canadian Consensus Criteria for adolescent chronic fatigue syndrome. Acta Paediatrica. volum 104 (5).
  Academic article
• Berg, Åse; Otterdal, Kari; Patel, Sam; Gonca, Miguel; David, Catarina; Dalen, Ingvild; Nymo, Stig Haugset; Nilsson, Margareta; Nordling, Sofia; Magnusson, Peetra U.; Ueland, Thor; Prato, Mauro; Giribaldi, Giuliana; Mollnes, Tom Eirik; Aukrust, Pål; Langeland, Nina; Nilsson, Per. (2015) Complement activation correlates with disease severity and contributes to cytokine responses in plasmodium falciparum malaria. Journal of Infectious Diseases. volum 212 (10).
  Academic article
• Bergstrøm, Bjarte; Aune, Marie Hjelmseth; Awuh, Jane Atesoh; Kojen, June Frengen; Blix, Kjetil Jordahl; Ryan, Liv; Flo, Trude Helen; Mollnes, Tom Eirik; Espevik, Terje; Stenvik, Jørgen. (2015) TLR8 senses Staphylococcus aureus RNA in human primary monocytes and macrophages and induces IFN-β production via a TAK1-IKKβ-IRF5 signaling pathway. Journal of Immunology. volum 195 (3).
  Academic article
• Blom, Anna M.; Österborg, Anders; Mollnes, Tom Eirik; Okroj, Marcin. (2015) Antibodies reactive to cleaved sites in complement proteins enable highly specific measurement of soluble markers of complement activation. Molecular Immunology. volum 66 (2).
  Academic article
• Egge, Kjetil Hagene; Barratt-Due, Andreas; Nymo, Stig Haugset; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Lau, Corinna; Espevik, Terje; Thorgersen, Ebbe Billmann; Mollnes, Tom Eirik. (2015) The anti-inflammatory effect of combined complement and CD14 inhibition is preserved during escalating bacterial load. Clinical and Experimental Immunology. volum 181 (3).
  Academic article
• Egge, Kjetil Hagene; Thorgersen, Ebbe Billmann; Pischke, Søren Erik; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Bongoni, Anjan K.; Rieben, Robert; Nunn, Miles A.; Barratt-Due, Andreas; Mollnes, Tom Eirik. (2015) Organ inflammation in porcine Escherichia coli sepsis is markedly attenuated by combined inhibition of C5 and CD14. Immunobiology. volum 220 (8).
  Academic article
• Engberg, Anna E.; Nilsson, Per; Huang, Shan; Fromell, Karin; Hamad, Osama A.; Mollnes, Tom Eirik; Rosengren-Holmberg, Jenny P; Sandholm, Kerstin; Teramura, Yuji; Nicholls, Ian A; Nilsson, Bo; Ekdahl, Kristina N.. (2015) Prediction of inflammatory responses induced by biomaterials in contact with human blood using protein fingerprint from plasma. Biomaterials. volum 36.
  Academic article
• Fretland, Åsmund Avdem; Sokolov, Andrey; Postriganova, Nadezda; Kazaryan, Airazat M.; Pischke, Søren Erik; Nilsson, Per; Rognes, Ingrid Nygren; Bjørnbeth, Bjørn Atle; Fagerland, Morten; Mollnes, Tom Eirik; Edwin, Bjørn. (2015) Inflammatory response after laparoscopic versus open resection of colorectal liver metastases: Data from the oslo-comet trial. Medicine. volum 94:e1786 (42).
  Academic article
• Hein, E; Munthe-Fog, Lea; Thiara, Amrit Paul Singh; Fiane, Arnt E; Mollnes, Tom Eirik; Garred, P. (2015) Heparin-coated cardiopulmonary bypass circuits selectively deplete the pattern recognition molecule ficolin-2 of the lectin complement pathway in vivo. Clinical and Experimental Immunology. volum 179 (2).
  Academic article
• Hellerud, Bernt C; Olstad, Ole Kristoffer; Nielsen, Erik W.; Siebke, Anne-Marie; Skadberg, Øyvind; Thorgersen, Ebbe Billmann; Vege, Åshild; Mollnes, Tom Eirik; Brandtzæg, Petter. (2015) Massive organ inflammation in experimental and in clinical meningococcal septic shock. Shock. volum 44 (5).
  Academic article
• Hovland, Anders; Jonasson, Lena; Garred, Peter; Yndestad, Arne; Aukrust, Pål; Lappegård, Knut Tore; Espevik, Terje; Mollnes, Tom Eirik. (2015) The complement system and toll-like receptors as integrated players in the pathophysiology of atherosclerosis. Atherosclerosis. volum 241 (2).
  Scientific translation/review
• Khan, Faraz Hameed; Pharo, Anne Margrethe; Lindstad, Julie Katrine; Mollnes, Tom Eirik; Tønnessen, Tor Inge; Pischke, Søren Erik. (2015) Effect of Perfusion Fluids on Recovery of Inflammatory Mediators in Microdialysis. Scandinavian Journal of Immunology. volum 82 (5).
  Academic article
• Landsem, Anne; Fure, Hilde; Christiansen, Dorte; Nielsen, Erik Waage; Østerud, Bjarne; Mollnes, Tom Eirik; Brekke, Ole Lars. (2015) The key roles of complement and tissue factor in Escherichia coli-induced coagulation in human whole blood. Clinical and Experimental Immunology. volum 182 (1).
  Academic article
• Lappegård, Knut Tore; Bjerre, Anna Kristina; Tjønnfjord, Geir Erland; Mollnes, Tom Eirik. (2015) Terapeutisk komplementhemming – fra eksperimentell til klinisk medisin. Tidsskrift for Den norske legeforening. volum 135 (19).
  Academic article
• Lappegård, Knut Tore; Bjørnstad, Hanne; Mollnes, Tom Eirik; Hovland, Anders. (2015) Effect of Cardiac Resynchronization Therapy on Inflammation in Congestive Heart Failure: A Review. Scandinavian Journal of Immunology. volum 82 (3).
  Scientific translation/review
• Lau, Corinna; Nygård, Ståle; Fure, Hilde; Olstad, Ole Kristoffer; Holden, Marit; Lappegård, Knut Tore; Brekke, Ole Lars; Espevik, Terje; Hovig, Johannes Eivind; Mollnes, Tom Eirik. (2015) CD14 and complement crosstalk and largely mediate the transcriptional response to Escherichia coli in human whole blood as revealed by DNA microarray. PLOS ONE. volum 10 (2).
  Academic article
• Lau, Corinna; Olstad, Ole Kristoffer; Holden, Marit; Nygård, Ståle; Fure, Hilde; Lappegård, Knut Tore; Brekke, Ole Lars; Espevik, Terje; Hovig, Johannes Eivind; Mollnes, Tom Eirik. (2015) Gene expression profiling of Gram-negative bacteria-induced inflammation in human whole blood: The role of complement and CD14-mediated innate immune response. Genomics Data. volum 5.
  Academic article
• Lindenskov, Paal Helge H.; Castellheim, Albert; Saugstad, Ola Didrik; Mollnes, Tom Eirik. (2015) Meconium aspiration syndrome: Possible pathophysiological mechanisms and future potential therapies. Neonatology. volum 107 (3).
  Scientific translation/review
• Neupane, Sudan Prasad; Lien, Lars; Ueland, Thor; Mollnes, Tom Eirik; Aukrust, Pål; Bramness, Jørgen Gustav. (2015) Serum brain-derived neurotrophic factor levels in relation to comorbid depression and cytokine levels in Nepalese men with alcohol-use disorders. Alcohol. volum 49 (5).
  Academic article
• Nilsson, Bo; Ekdahl, Kristina Nilsson; Kemper, Claudia; Mollnes, Tom Eirik. (2015) Preface. Molecular Immunology. volum 67 (1).
  Editorial
• Niyonzima, Nathalie; Samstad, Eivind; Aune, Marie Hjelmseth; Ryan, Liv; Bakke, Siril Skaret; Rokstad, Anne Mari; Wright, Samuel; Damås, Jan Kristian; Mollnes, Tom Eirik; Latz, Eicke; Espevik, Terje. (2015) Reconstituted high-density lipoprotein attenuates cholesterol crystal-induced inflammatory responses by reducing complement activation. Journal of Immunology. volum 195 (1).
  Academic article
• Owen, E. Patricia; Würzner, Reinhard; Leisegang, Felicity; Rizkallah, Pierre; Whitelaw, Andrew; Simpson, John; Thomas, Andrew D.; Harris, Claire L.; Giles, Joanna L.; Hellerud, Bernt C; Mollnes, Tom Eirik; Morgan, B. Paul; Potter, Paul C.; Orren, Ann. (2015) A complement C5 gene mutation, c.754G>A:p.A252T, is common in the Western Cape, South Africa and found to be homozygous in seven percent of Black African meningococcal disease cases. Molecular Immunology. volum 64 (1).
  Academic article
• Prebensen, Christian; Ueland, Thor; Michelsen, Annika; Lind, Andreas; Pettersen, Frank Olav; Mollnes, Tom Eirik; Aukrust, Pål; Dyrhol-Riise, Anne Ma; Kvale, Dag. (2015) High MIP-1β levels in plasma predict long-term immunological nonresponse to suppressive antiretroviral therapy in HIV infection. Journal of Acquired Immune Deficiency Syndromes. volum 69 (4).
  Academic article
• Skjeflo, Espen Waage; Sagatun, Caroline; Dybwik, Knut; Aam, Sturla; Urving, Sven Haakon; Nunn, Miles A.; Fure, Hilde; Lau, Corinna; Brekke, Ole Lars; Huber-Lang, Markus; Espevik, Terje; Barratt-Due, Andreas; Nielsen, Erik Waage; Mollnes, Tom Eirik. (2015) Combined inhibition of complement and CD14 improved outcome in porcine polymicrobial sepsis. Critical Care. volum 19:415.
  Academic article
• Smedbråten, Yuliya V.; Sagedal, Solbjørg; Mjøen, Geir; Hartmann, Anders; Fagerland, Morten; Rollag, Halvor; Mollnes, Tom Eirik; Thiel, Steffen. (2015) High Ficolin-3 level at the time of transplantation is an independent risk factor for graft loss in kidney transplant recipients. Transplantation. volum 99 (4).
  Academic article
• Volokhina, E.B.; Westra, Dineke; van der Velden, Thea J.A.M.; van de Kar, Nicole C.A.J.; Mollnes, Tom Eirik; van den Heuvel, Lambert P.. (2015) Complement activation patterns in atypical haemolytic uraemic syndrome during acute phase and in remission. Clinical and Experimental Immunology. volum 181 (2).
  Academic article
• Volokhina, Elena B.; Bergseth, Grethe; van de Kar, Nicole C.A.J.; van den Heuvel, Lambertus P.; Mollnes, Tom Eirik. (2015) Eculizumab treatment efficiently prevents C5 cleavage without C5a generation in vivo. Blood. volum 126 (2).
  Letter to the editor
• Volokhina, Elena B.; van de Kar, Nicole C.A.J.; Bergseth, Grethe; van der Velden, Thea J.A.M.; Westra, Dineke; Wetzels, Jack F.M.; van den Heuvel, Lambertus P.; Mollnes, Tom Eirik. (2015) Sensitive, reliable and easy-performed laboratory monitoring of eculizumab therapy in atypical hemolytic uremic syndrome. Clinical Immunology. volum 160 (2).
  Academic article
• Wergeland, Ida; Pullar, Nadine Durema; Assmus, Jörg; Ueland, Thor; Tonby, Kristian; Feruglio, Siri; Kvale, Dag; Damås, Jan Kristian; Aukrust, Pål; Mollnes, Tom Eirik; Dyrhol-Riise, Anne Ma. (2015) IP-10 differentiates between active and latent tuberculosis irrespective of HIV status and declines during therapy. Journal of Infection. volum 70 (4).
  Academic article
• Würzner, Reinhard; Tedesco, Francesco; Garred, Peter; Mollnes, Tom Eirik; Truedsson, Lennart; Turner, Malcolm W.; Sommarin, Yngve; Wieslander, Jörgen; Sim, Robert B.. (2015) European Union funded project on the development of a whole complement deficiency screening ELISA-A story of success and an exceptional manager: Mohamed R. Daha. Molecular Immunology. volum 68 (1).
  Scientific translation/review
• Wyller, Vegard Bruun; Reme, Silje; Mollnes, Tom Eirik. (2015) Kronisk utmattelsessyndrom/myalgisk encefalopati – sykdomsmekanismer, diagnostikk og behandling. Tidsskrift for Den norske legeforening. volum 135 (23/24).
  Chronicle
• Wyller, Vegard Bruun; Sørensen, Øystein; Sulheim, Dag; Fagermoen, Frode Even; Ueland, Thor; Mollnes, Tom Eirik. (2015) Plasma cytokine expression in adolescent chronic fatigue syndrome. Brain, Behavior, and Immunity. volum 46.
  Academic article

2014

• Bergseth, Grethe; Ludviksen, Judith K; Kirschfink, Michael; Giclas, Patricia C.; Nilsson, Bo; Mollnes, Tom Eirik. (2014) Corrigendum to "An international serum standard for application in assays to detect human complement activation products" [Mol. Immunol. 56 (2013) 232-239]. Molecular Immunology. volum 60 (2).
  Errata
• Berg, Åse; Patel, Sam; Gonca, Miguel; Catarina, David; Otterdal, Kari; Ueland, Thor; Dalen, Ingvild; Kvaløy, Jan Terje; Mollnes, Tom Eirik; Aukrust, Pål; Langeland, Nina. (2014) Cytokine network in adults with falciparum malaria and HIV-1: increased IL-8 and IP-10 levels are associated with disease severity. PLOS ONE. volum 9 (12).
  Academic article
• Bisschops, Laurens L.A.; van der Hoeven, Johannes G.; Mollnes, Tom Eirik; Hoedemaekers, Cornelia W.E.. (2014) Seventy-two hours of mild hypothermia after cardiac arrest is associated with a lowered inflammatory response during rewarming in a prospective observational study. Critical Care. volum 18 (546).
  Academic article
• Blom, AM; Volokhina, E.B.; Fransson, V; Strömberg, P; Berghard, L; Viktorelius, M; Mollnes, Tom Eirik; Lopez-Trascasa, M; van den Heuvel, Lambert P.; Goodship, T.H.; Marchbank, K; Okroj, M. (2014) A novel method for direct measurement of complement convertases activity in human serum. Clinical and Experimental Immunology. volum 178 (1).
  Academic article
• Egge, Kjetil Hagene; Thorgersen, Ebbe Billmann; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Lambris, John D.; Barratt-Due, Andreas; Mollnes, Tom Eirik. (2014) Post challenge inhibition of C3 and CD14 attenuates Escherichia coli-induced inflammation in human whole blood. Innate Immunity. volum 20 (1).
  Academic article
• Huber-Lang, Markus; Barratt-Due, Andreas; Pischke, Søren Erik; Sandanger, Øystein; Nilsson, Per; Nunn, Miles A.; Denk, Stephanie; Gaus, Wilhelm; Espevik, Terje; Mollnes, Tom Eirik. (2014) Double blockade of CD14 and complement C5 abolishes the cytokine storm and improves morbidity and survival in polymicrobial sepsis in mice. Journal of Immunology. volum 192 (11).
  Academic article
• Lappegård, Knut Tore; Garred, Peter; Jonasson, Lena; Espevik, Terje; Aukrust, Pål; Yndestad, Arne; Mollnes, Tom Eirik; Hovland, Anders. (2014) A vital role for complement in heart disease. Molecular Immunology. volum 61 (2).
  Scientific translation/review
• Lind, Andreas; Brekke, Kristin; Pettersen, Frank Olav; Mollnes, Tom Eirik; Trøseid, Marius; Kvale, Dag. (2014) A parameter for IL-10 and TGF-β mediated regulation of HIV-1 specific T cell activation provides novel information and relates to progression markers. PLOS ONE. volum 9 (1).
  Academic article
• Neupane, Sudan Prasad; Lien, Lars; Martinez, Priscilla; Aukrust, Pål; Ueland, Thor; Mollnes, Tom Eirik; Hestad, Knut; Bramness, Jørgen Gustav. (2014) High frequency and intensity of drinking may attenuate increased inflammatory cytokine levels of major depression in alcohol-use disorders. CNS Neuroscience & Therapeutics. volum 20 (10).
  Academic article
• Nymo, Stig Haugset; Niyonzima, Nathalie; Espevik, Terje; Mollnes, Tom Eirik. (2014) Cholesterol crystal-induced endothelial cell activation is complement-dependent and mediated by TNF. Immunobiology. volum 219 (10).
  Academic article
• Salvesen, Bodil; Curstedt, Tore; Mollnes, Tom Eirik; Saugstad, Ola Didrik. (2014) Effects of natural versus synthetic surfactant with SP-B and SP-C analogs in a porcine model of meconium aspiration syndrome. Neonatology. volum 105 (2).
  Academic article
• Samstad, Eivind; Niyonzima, Nathalie; Nymo, Stig Haugset; Aune, Marie Hjelmseth; Ryan, Liv; Bakke, Siril Skaret; Lappegård, Knut Tore; Brekke, Ole Lars; Lambris, John D.; Damås, Jan Kristian; Latz, Eicke; Mollnes, Tom Eirik; Espevik, Terje. (2014) Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release. Journal of Immunology. volum 192 (6).
  Academic article
• Skjeflo, Espen Waage; Christiansen, Dorte; Espevik, Terje; Nielsen, Erik Waage; Mollnes, Tom Eirik. (2014) Combined inhibition of complement and CD14 efficiently attenuated the inflammatory response induced by staphylococcus aureus in a human whole blood model. Journal of Immunology. volum 192 (6).
  Academic article
• van Vuuren, B. Jansen; Bergseth, Grete; Mollnes, Tom Eirik; Shaw, A.M.. (2014) Electroluminescent TCC, C3dg and fB/Bb epitope assays for profiling Complement cascade activation in vitro using an activated Complement serum calibration standard. JIM - Journal of Immunological Methods. volum 402.
  Academic article
• Østvik, Ann Elisabet; Granlund, Atle Van Beelen; Gustafsson, Björn; Torp, Sverre Helge; Espevik, Terje; Mollnes, Tom Eirik; Damås, Jan Kristian; Sandvik, Arne Kristian. (2014) Mucosal toll-like receptor 3-dependent synthesis of complement factor B and systemic complement activation in inflammatory bowel disease. Inflammatory Bowel Diseases. volum 20 (6).
  Academic article
• Øvstebø, Reidun; Hellum, Marit Synnøve; Aass, Hans Christian; Siebke, Anne-Marie; Brandtzæg, Petter; Mollnes, Tom Eirik; Henriksson, Carola. (2014) Microparticle-associated tissue factor activity is reduced by inhibition of the complement protein 5 in Neisseria meningitidis-exposed whole blood. Innate Immunity. volum 20 (5).
  Academic article

2013

• Lau, Corinna; Gunnarsen, Kristin Støen; Høydahl, Lene Støkken; Andersen, Jan Terje; Berntzen, Gøril; Pharo, Anne Margrethe; Lindstad, Julie Katrine; Ludviksen, Judith K; Brekke, Ole Lars; Barratt-Due, Andreas; Nielsen, Erik Waage; Stokes, Christopher R.; Espevik, Terje; Sandlie, Inger; Mollnes, Tom Eirik. (2013) Chimeric Anti-CD14 IGG2/4 Hybrid Antibodies for Therapeutic Intervention in Pig and Human Models of Inflammation. Journal of Immunology. volum 191 (9).
  Academic article
• Auråen, Henrik; Mollnes, Tom Eirik; Bjørtuft, Øystein; Bakkan, Per Arne; Geiran, Odd; Kongerud, Johny; Fiane, Arnt E; Holm, Are Martin. (2013) Multiorgan procurement increases systemic inflammation in brain dead donors. Clinical Transplantation. volum 27 (4).
  Academic article
• Barratt-Due, Andreas; Sokolov, Andrey; Gustavsen, Alice; Hellerud, Bernt C; Egge, Kjetil Hagene; Pischke, Søren Erik; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Castellheim, Albert; Thorgersen, Ebbe Billmann; Mollnes, Tom Eirik. (2013) Polyvalent immunoglobulin significantly attenuated the formation of IL-1 beta in Escherichia coli-induced sepsis in pigs. Immunobiology. volum 218 (5).
  Academic article
• Barratt-Due, Andreas; Thorgersen, Ebbe Billmann; Egge, Kjetil Hagene; Pischke, Søren Erik; Sokolov, Andrey; Hellerud, Bernt C; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Bongoni, Anjan K.; Rieben, Robert; Nunn, Miles; Scott, Helge; Mollnes, Tom Eirik. (2013) Combined Inhibition of Complement (C5) and CD14 Markedly Attenuates Inflammation, Thrombogenicity, and Hemodynamic Changes in Porcine Sepsis. Journal of Immunology. volum 191 (2).
  Academic article
• Bergseth, Grete; Ludviksen, Judith K; Kirschfink, Michael; Giclas, Patricia C.; Nilsson, Bo; Mollnes, Tom Eirik. (2013) An international serum standard for application in assays to detect human complement activation products. Molecular Immunology. volum 56 (3).
  Scientific translation/review
• Brekke, Ole Lars; Landsem, Anne; Fure, Hilde; Christiansen, Dorte; Nielsen, Erik Waage; Lambris, J.D.; Mollnes, Tom Eirik. (2013) Key role of tissue factor in complement-mediated coagulation activation by Escherichia coli and LPS. Molecular Immunology. volum 56 (3).
  Summary/Abstract
• Brekke, Ole Lars; Waage, Knut-Christian; Christiansen, Dorte; Fure, Hilde; Qu, H; Lambris, John D.; Østerud, Bjarne; Nielsen, Erik Waage; Mollnes, Tom Eirik. (2013) The Effects of Selective Complement and CD14 Inhibition on the E. coli -Induced Tissue Factor mRNA Upregulation, Monocyte Tissue Factor Expression, and Tissue Factor Functional Activity in Human Whole Blood. Complement Therapeutics, Advances in Experimental Medicine and Biology.
  Academic chapter/article
• Egge, Kjetil Hagene; Thorgersen, Ebbe Billmann; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Bongoni, AK; Rieben, R; Barratt-Due, Andreas; Mollnes, Tom Eirik. (2013) Combined inhibition of C5 and CD14 attenuates organ inflammation in porcine Escherichia coli sepsis. Molecular Immunology. volum 56 (3).
  Summary/Abstract
• Egge, Kjetil Hagene; Thorgersen, Ebbe Billmann; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Lambris, J.D.; Barratt-Due, Andreas; Mollnes, Tom Eirik. (2013) Combined inhibition of C3 and CD14 attenuates the inflammatory reaction significantly more as compared to single inhibition. Molecular Immunology. volum 56 (3).
  Summary/Abstract
• Ehrnthaller, Christian; Huber-Lang, Markus; Nilsson, Per H.; Bindl, Ronny; Redeker, Simon; Recknagel, Stefan; Rapp, Anna; Mollnes, Tom Eirik; Amling, Michael; Gebhard, Florian; Ignatius, Anita. (2013) Complement C3 and C5 deficiency affects fracture healing. PLOS ONE. volum 8 (11:e81341).
  Academic article
• Engberg, AE; Nilsson, Per H.; Sandholm, K; Huang, S; Mollnes, Tom Eirik; Nicholls, IA; Nilsson, B; Ekdahl, KN. (2013) The ratio between C4 and C4BP adsorbed to artificial materials is a new predictor for biocompatibility. Molecular Immunology. volum 56 (3).
  Summary/Abstract
• Granslo, Hildegunn Norbakken; Klingenberg, Claus; Fredheim, Elizabeth A.; Acharya, Ganesh; Mollnes, Tom Eirik; Flægstad, Trond. (2013) Staphylococcus epidermidis biofilms induce lower complement activation in neonates as compared with adults. Pediatric Research. volum 73 (3).
  Academic article
• Gregersen, Ida; Skjelland, Mona; Holm, Sverre; Holven, Kirsten Bjørklund; Sørensen, Kirsten; Russell, David; Askevold, Erik Tandberg; Dahl, Christen Peder; Ørn, Stein; Gullestad, Lars; Mollnes, Tom Eirik; Ueland, Thor; Aukrust, Pål; Halvorsen, Bente. (2013) Increased Systemic and Local Interleukin 9 Levels in Patients with Carotid and Coronary Atherosclerosis. PLOS ONE. volum 8 (8).
  Academic article
• Hamre, Hanne Mari; Zeller, Bernward; Kanellopoulos, Adriani; Ruud, Ellen; Fosså, Sophie Dorothea; Loge, Jon Håvard; Aukrust, Pål; Halvorsen, Bente; Mollnes, Tom Eirik; Kiserud, Cecilie E.. (2013) Serum cytokines and chronic fatigue in adults surviving after childhood leukemia and lymphoma. Brain, Behavior, and Immunity. volum 30.
  Academic article
• Happonen, Kaisa E.; Saxne, Tore; Jacobsson, Lennart; Sturfelt, Gunnar; Rönnelid, Johan; Mollnes, Tom Eirik; Heinegard, Dick; Turesson, Carl; Blom, Anna M.. (2013) COMP-C3b Complexes in Rheumatoid Arthritis with Severe Extraarticular Manifestations. Journal of Rheumatology. volum 40 (12).
  Academic article
• Haugaa, Håkon; Almaas, Runar; Thorgersen, Ebbe Billmann; Foss, Aksel; Line, Pål Dag; Sanengen, Truls; Bergmann, Gisli Bjørn; Olin, Per Bertil Mårten; Wælgaard, Lars Torbjørn; Grindheim, Guro; Pischke, Søren Erik; Mollnes, Tom Eirik; Tønnessen, Tor Inge. (2013) Clinical experience with microdialysis catheters in pediatric liver transplants. Liver transplantation. volum 19 (3).
  Academic article
• Landsem, A; Fure, Hilde; Nielsen, Erik Waage; Mollnes, Tom Eirik; Brekke, Ole Lars. (2013) Effects of C1-inhibitor on clot development in human whole blood analyzed using rotational thromboelastography. Molecular Immunology. volum 56 (3).
  Summary/Abstract
• Landsem, Anne; Nielsen, Erik Waage; Fure, Hilde; Christiansen, Dorte; Ludviksen, Judith K; Lambris, J.D.; Østerud, Bjarne; Mollnes, Tom Eirik; Brekke, Ole Lars. (2013) C1-inhibitor efficiently inhibits Escherichia coli-induced tissue factor mRNA up-regulation, monocyte tissue factor expression and coagulation activation in human whole blood. Clinical and Experimental Immunology. volum 173 (2).
  Academic article
• Lappegård, Knut Tore; Hovland, Anders; Pop, Gheorghe A.; Mollnes, Tom Eirik. (2013) Atrial Fibrillation: Inflammation in Disguise?. Scandinavian Journal of Immunology. volum 78 (2).
  Scientific translation/review
• Mollnes, Tom Eirik; Barratt-Due, Andreas; Pischke, Søren Erik; Sandanger, Inger; Nilsson, Per; Lambris, J; Nunn, Miles A.; Denk, Stephanie; Espevik, Terje; Huber-Lang, Markus. (2013) Double-blockade of CD14 and complement component C5 abolish the inflammatory storm and improve survival in mouse polymicrobial sepsis. Molecular Immunology. volum 56 (3).
  Summary/Abstract
• Mollnes, Tom Eirik; Nilsson, Per H.. (2013) Untitled. Journal of clinical biochemistry and nutrition. volum 52 (3).
  Letter to the editor
• Nymo, Stig Haugset; Samstad, Eivind; Niyonzima, Nathalie; Aune, Marie Hjelmseth; Bergseth, Grete; Ryan, Liv; Brekke, Ole Lars; Latz, E; Lambris, J.D.; Espevik, Terje; Mollnes, Tom Eirik. (2013) Cholesterol crystals activate the complement system and are phagocytosed in a complement-dependent manner. Molecular Immunology. volum 56 (3).
  Summary/Abstract
• Prohaszka, Zoltan; Munthe-Fog, Lea; Ueland, Thor; Gombos, Timea; Yndestad, Arne; Forhecz, Zsolt; Skjoedt, Mikkel-Ole; Pozsonyi, Zoltan; Gustavsen, Alice; Janoskuti, Livia; Karadi, Istvan; Gullestad, Lars; Dahl, Christen Peder; Askevold, Erik Tandberg; Füst, George; Aukrust, Pål; Mollnes, Tom Eirik; Garred, Peter. (2013) Association of Ficolin-3 with Severity and Outcome of Chronic Heart Failure. PLOS ONE. volum 8 (4).
  Academic article
• Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Strand, Berit Løkensgard; Skjåk-Bræk, Gudmund; Lambris, John D.; Lacík, Igor; Mollnes, Tom Eirik; Espevik, Terje. (2013) The induction of cytokines by polycation containing microspheres by a complement dependent mechanism. Biomaterials. volum 34 (3).
  Academic article
• Rokstad, Anne Mari; Strand, Berit Løkensgard; Espevik, Terje; Mollnes, Tom Eirik. (2013) Biocompatibility and Biotolerability Assessment of Microspheres Using a Whole Blood Model. Micro and Nanosystems. volum 5 (3).
  Academic article
• Samstad, Eivind; Niyonzima, Nathalie; Nymo, Stig Haugset; Aune, Marie Hjelmseth; Ryan, Liv; Brekke, Ole Lars; Sandanger, I; Aukrust, Pål; Damås, Jan Kristian; Latz, Eicke; Lambris, J.D.; Mollnes, Tom Eirik; Espevik, Terje. (2013) Cholesterol crystals induce inflammasome activation and cytolcine release in a complement-dependent manner. Molecular Immunology. volum 56 (3).
  Summary/Abstract
• Schejbel, Lone; Fadnes, Dag Jone Stokke; Permin, Henrik; Lappegård, Knut Tore; Garred, Peter; Mollnes, Tom Eirik. (2013) Primary complement C5 deficiencies - Molecular characterization and clinical review of two families. Immunobiology. volum 218 (10).
  Scientific translation/review
• Sokolov, Andrey; Hellerud, Bernt C; Tønnessen, Tor Inge; Johannessen, Erik; Mollnes, Tom Eirik. (2013) Activation of coagulation and platelets by candidate membranes of implantable devices in a whole blood model without soluble anticoagulant. Journal of Biomedical Materials Research. Part A. volum 101A (2).
  Academic article
• Thorgersen, Ebbe Billmann; Pischke, Søren Erik; Barratt-Due, Andreas; Fure, Hilde; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Hellerud, Bernt C; Mollnes, Tom Eirik. (2013) Systemic CD14 inhibition attenuates organ inflammation in porcine escherichia coli sepsis. Infection and Immunity. volum 81 (9).
  Academic article

2012

• Bergseth, Grethe; Hallstensen, R.F.; Jaeger, Steinar; Christiansen, Dorte; Holt, jan; Mollnes, Tom Eirik. (2012) A novel method for detection of eculizumab in complex with C5: Application in serum from a pregnant patient and her newborn child. Immunobiology. volum 217 (11).
  Summary/Abstract
• Nymo, Stig; Samstad, Eivind; Niyonzima, Nathalie; Bergseth, Grethe; Christiansen, Dorte; Ryan, Liv; Brekke, Ole Lars; Lappegard, Knut Tore; Damas, Jan Kristian; Latz, Eicke; Lambris, John D.; Espevik, Terje; Mollnes, Tom Eirik. (2012) Complement dependency of cholesterol crystal-induced inflammation - I. Pathway activation mechanisms, cytokine responses and endothelial cell activation. Immunobiology. volum 217 (11).
  Summary/Abstract
• Almaas, Runar; Hankø, Erik; Mollnes, Tom Eirik; Rootwelt, Terje. (2012) Dexamethasone reduces bilirubin-induced toxicity and IL-8 and MCP-1 release in human NT2-N neurons. Brain Research. volum 1458.
  Academic article
• Auråen, Henrik; Mollnes, Tom Eirik; Kongerud, Johny; Bjørtuft, Øystein; Geiran, Odd; Fiane, Arnt E; Holm, Are Martin. (2012) Procedure for solid organ recovery leads to systemic inflammatory response. The Journal of Heart and Lung Transplantation. volum 31 (4).
  Summary/Abstract
• Barratt-Due, Andreas; Pischke, Søren Erik; Brekke, Ole Lars; Thorgersen, Ebbe Billmann; Nielsen, Erik Waage; Espevik, Terje; Huber-Lang, Markus; Mollnes, Tom Eirik. (2012) Bride and groom in systemic inflammation - The bells ring for complement and Toll in cooperation. Immunobiology. volum 217 (11).
  Scientific translation/review
• Barratt-Duel, Andreas; Thorgersen, Ebbe Billmann; Egge, Kjetil Hagene; Pischke, Søren Erik; Sokolov, Andrey; Hellerud, Bernt C; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Nunn, Miles A.; Scott, Helge; Mollnes, Tom Eirik. (2012) Combined inhibition of complement (C5) and CD14 markedly attenuates blood thrombogenicity, inflammation and hemodynamic changes in porcine sepsis. Immunobiology. volum 217 (11).
  Summary/Abstract
• Bisschops, Laurens L.A.; Hoedemaekers, Cornelia W.E.; Mollnes, Tom Eirik; van der Hoeven, Johannes G.. (2012) Rewarming after hypothermia after cardiac arrest shifts the inflammatory balance. Critical Care Medicine. volum 40 (4).
  Academic article
• Brekke, Ole Lars; Landsem, Anne; Fure, Hilde; Christiansen, Dorte; Nielsen, Erik Waage; Lambris, John D.; Mollnes, Tom Eirik. (2012) Escherichia coli-induced coagulation activation and pentraxin 3 release is highly dependent on complement and CD14. Immunobiology. volum 217 (11).
  Summary/Abstract
• Christiansen, Dorte; Brekke, Ole Lars; Stenvik, Jørgen; Lambris, J.D.; Espevik, Terje; Mollnes, Tom Eirik. (2012) Differential Effect of Inhibiting MD-2 and CD14 on LPS- Versus Whole E. coli Bacteria-Induced Cytokine Responses in Human Blood. Advances in Experimental Medicine and Biology. volum 946.
  Academic article
• Christiansen, Dorte; Stenvik, Jørgen; Brekke, Ole Lars; Lambris, John D.; Espevik, Terje; Mollnes, Tom Eirik. (2012) Phagocytosis of Escherichia coli in human whole blood: Early complement dependency is succeeded by late CD14 dependency over time. Immunobiology. volum 217 (11).
  Summary/Abstract
• Egge, Kjetil Hagene; Thorgersen, Ebbe Billmann; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Barratt-Due, Andreas; Mollnes, Tom Eirik. (2012) An ex vivo posttreatment model of sepsis: Effect on inflammation by adding complement- and CD14-inhibitors after E. coli to human whole blood. Immunobiology. volum 217 (11).
  Summary/Abstract
• Engberg, Anna E.; Nilsson, Per H.; Mollnes, Tom Eirik; Rosengren-Holmberg, Jenny P; Nicholls, Ian A; Nilsson, Bo; Ekdahl, Kristina N.. (2012) The ratio between C4 and C4BP adsorbed from plasma predicts cytokine generation induced by artificial polymers in contact with whole blood. Immunobiology. volum 217 (11).
  Summary/Abstract
• Harboe, Morten; Gaffed, Peter; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Müller, Fredrik; Stahl, Gregory L; Lambris, John D.; Mollnes, Tom Eirik. (2012) The role of properdin in zymosan- and Escherichia coli-induced complement activation. Immunobiology. volum 217 (11).
  Summary/Abstract
• Harboe, Morten; Garred, Peter; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Müller, Fredrik; Stahl, Gregory L; Lambris, John D.; Mollnes, Tom Eirik. (2012) The Role of Properdin in Zymosan- and Escherichia coli-Induced Complement Activation. Journal of Immunology. volum 189 (5).
  Academic article
• Haugaa, Håkon; Thorgersen, Ebbe Billmann; Pharo, Anne Margrethe; Boberg, Kirsten Muri; Foss, Aksel; Line, Pål Dag; Sanengen, Truls; Almaas, Runar; Grindheim, Guro; Wælgaard, Lars Torbjørn; Pischke, Søren Erik; Mollnes, Tom Eirik; Tønnessen, Tor Inge. (2012) Inflammatory markers sampled by microdialysis catheters distinguish rejection from ischemia in liver grafts. Liver transplantation. volum 18 (12).
  Academic article
• Haugaa, Håkon; Thorgersen, Ebbe Billmann; Pharo, Anne Margrethe; Boberg, Kirsten Muri; Foss, Aksel; Line, Pål Dag; Sanengen, Truls; Almaas, Runar; Grindheim, Guro; Pischke, Søren Erik; Mollnes, Tom Eirik; Tønnessen, Tor Inge. (2012) Early bedside detection of ischemia and rejection in liver transplants by microdialysis. Liver transplantation. volum 18 (7).
  Academic article
• Hovland, Anders Wilhelm; Marcovina, Santica; Hardersen, Randolf; Enebakk, Terje; Mollnes, Tom Eirik; Lappegård, Knut Tore. (2012) Three different LDL apheresis columns efficiently and equally reduce lipoprotein(a) concentrations in patients with familial hypercholesterolemia and small apolipoprotein(a) particles. Transfusion and Apheresis Science. volum 46 (1).
  Academic article
• Hovland, Anders; Hardersen, Randolf; Nielsen, Erik Waage; Enebakk, Terje; Christiansen, Dorte; Ludviksen, Judith K; Mollnes, Tom Eirik; Lappegård, Knut Tore. (2012) Complement profile and activation mechanisms by different LDL apheresis systems. Acta Biomaterialia. volum 8 (6).
  Academic article
• Hovland, Anders; Lappegård, Knut Tore; Mollnes, Tom Eirik. (2012) LDL Apheresis and Inflammation - Implications for Atherosclerosis. Scandinavian Journal of Immunology. volum 76 (3).
  Scientific translation/review
• Kvarnström, A.; Sokolov, Andrey; Swartling, T.; Kuriberg, G.; Mollnes, Tom Eirik; Bengtsson, A. (2012) Alternative Pathway Activation of Complement in Laparoscopic and Open Rectal Surgery. Scandinavian Journal of Immunology. volum 76 (1).
  Academic article
• Landsem, Anne; Nielsen, Erik Waage; Christiansen, Dorte; Mollnes, Tom Eirik; Brekke, Ole Lars. (2012) C1-inhibitor efficiently inhibits Escherichia coli-induced tissue factor mRNA up-regulation, monocyte tissue factor expression and coagulation activation in human whole blood. Immunobiology. volum 217 (11).
  Summary/Abstract
• Lau, Corinna; Gunnarsen, Kristin Støen; Høydahl, Lene Støkken; Berntzen, Gøril; Stokes, Christopher R.; Espevik, Terje; Sandlie, Inger; Mollnes, Tom Eirik. (2012) Recombinant anti-human and anti-porcine CD14 antibodies. Immunobiology. volum 217 (11).
  Summary/Abstract
• Ludviksen, Judith K; Hovland, Anders; Lappegard, KT; Mollnes, Tom Eirik. (2012) Evidence of classical complement activation during blood-biomaterial interaction in LDL apheresis. Immunobiology. volum 217 (11).
  Summary/Abstract
• Mollnes, Tom Eirik; Barratt-Due, Andreas; Pischke, Søren Erik; Sandanger, Øystein; Nunn, Miles A.; Espevik, Terje; Denk, Stephanie; Huber-Lang, Markus. (2012) The systemic inflammatory reaction in polymicrobial sepsis induced by murine cecal ligation and puncture is equally dependent on C5 and CD14. Immunobiology. volum 217 (11).
  Summary/Abstract
• Niyonzima, Nathalie; Samstad, Eivind; Aune, Marie Hjelmseth; Ryan, Liv; Damås, Jan Kristian; Wright, Samuel; Sandanger, Øystein; Aukrust, Pål; Latz, Eicke; Mollnes, Tom Eirik; Espevik, Terje. (2012) Complement dependency of cholesterol crystal-induced inflammation - II. Inflammasome activation and regulation mechanisms involving reconstituted high density lipoprotein (HDL) and C-reactive protein (CRP). Immunobiology. volum 217 (11).
  Summary/Abstract
• Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Lambris, John D.; Lacík, Igor; Mollnes, Tom Eirik; Espevik, Terje. (2012) Poly-cation containing alginate microcapsules induce cytokines by a complement-dependent mechanism. Immunobiology. volum 217 (11).
  Summary/Abstract
• Rødland, Ernst Kristian; Ueland, Thor; Bjørnsen, Stine; Sagen, Ellen Lund; Dahl, Christen Peder; Naalsund, Anne; Mollnes, Tom Eirik; Brosstad, Frank Roger; Müller, Fredrik; Aukrust, Pål; Frøland, Stig Sophus. (2012) Systemic biomarkers of inflammation and haemostasis in patients with chronic necrotizing pulmonary aspergillosis. BMC Infectious Diseases. volum 12.
  Academic article
• Salvesen, B.; Curstedt, Tore; Mollnes, Tom Eirik; Saugstad, Ola Didrik. (2012) Natural versus Synthetic Surfactant in an Experimental Model of Meconium Aspiration Syndrome. Neonatology. volum 101 (4).
  Summary/Abstract
• Skjeflo, Espen; Christiansen, Dorte; Lambris, John D.; Espevik, Terje; Nielsen, Erik Waage; Mollnes, Tom Eirik. (2012) Combined inhibition of complement and CD14 efficiently attenuated the inflammatory response induced by Staphylococcus aureus in a human whole blood model. Immunobiology. volum 217 (11).
  Summary/Abstract
• Sokolov, Andrey; Hellerud, Bernt C; Johannessen, Erik; Mollnes, Tom Eirik. (2012) Inflammatory response induced by candidate biomaterials of an implantable microfabricated sensor. Journal of Biomedical Materials Research. Part A. volum 100A (5).
  Academic article
• Thorgersen, Ebbe Billmann; Pischke, Søren Erik; Barratt-Due, Andreas; Fure, Hilde; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Hellerud, Bernt C; Mollnes, Tom Eirik. (2012) Systemic CD14-inhibition attenuates local inflammatory responses organ-dependently in porcine Escherichia coli-sepsis. Immunobiology. volum 217 (11).
  Summary/Abstract
• Ørn, Stein; Ueland, Toril; Manhenke, Cord A; Sandanger, Øystein; Godang, Kristin; Yndestad, Arne; Mollnes, Tom Eirik; Dickstein, Kenneth; Aukrust, Pål. (2012) Increased interleukin-1 beta levels are associated with left ventricular hypertrophy and remodelling following acute ST segment elevation myocardial infarction treated by primary percutaneous coronary intervention. Journal of Internal Medicine. volum 272 (3).
  Academic article

2011

• Aarag, Elizabeth; Granslo, Hildegunn Norbakken; Flægstad, Trond; Figenschau, Yngve; Rohde, H; Sadovskaya, I; Mollnes, Tom Eirik; Klingenberg, Claus. (2011) Staphylococcus epidermidis polysaccharide intercellular adhesin activates complement. FEMS Immunology and Medical Microbiology. volum 63 (2).
  Academic article
• Barratt-Due, Andreas; Johansen, Harald Thidemann; Sokolov, Andrey; Thorgersen, Ebbe Billmann; Hellerud, Bernt C; Reubsaet, Leon; Seip, Knut Fredrik; Tønnessen, Tor Inge; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Castellheim, Albert; Mollnes, Tom Eirik; Nielsen, Erik Waage. (2011) The Role of Bradykinin and the Effect of the Bradykinin Receptor Antagonist Icatibant in Porcine Sepsis. Shock. volum 36 (5).
  Academic article
• Barratt-Due, Andreas; Thorgersen, Ebbe Billmann; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Lissina, Olga; Lambris, John D.; Nunn, Miles A.; Mollnes, Tom Eirik. (2011) Ornithodoros moubata Complement Inhibitor Is an Equally Effective C5 Inhibitor in Pigs and Humans. Journal of Immunology. volum 187 (9).
  Academic article
• Berdal, Jan Erik; Mollnes, Tom Eirik; Wæhre, Torgun; Olstad, Ole Kristoffer; Halvorsen, Bente; Ueland, Thor; Laake, Jon Henrik; Furuseth, May T; Maagaard, Anne; Kjekshus, Harald; Aukrust, Pål; Jonassen, Christine M. (2011) Excessive innate immune response and mutant D222G/N in severe A (H1N1) pandemic influenza. Journal of Infection. volum 63 (4).
  Academic article
• Bergseth, Grete; Lambris, John D.; Mollnes, Tom Eirik; Lappegård, Knut Tore. (2011) Artificial Surface-Induced Inflammation Relies on Complement Factor 5: Proof From a Deficient Person. Annals of Thoracic Surgery. volum 91 (2).
  Academic article
• Brekke, Ole Lars; Christiansen, Dorte; Gay, B. Donvito; Fure, Hilde; Reveil, Bert; Kisserli, A.; Mollnes, Tom Eirik; Cohen, J. H. M.. (2011) Key role of the number of erythrocyte CR1 on the initial erythrocyte binding, phagocytosis and oxidative burst by Escherichia coli in human whole blood. Molecular Immunology. volum 48 (14).
  Summary/Abstract
• Brekke, Ole Lars; Hellerud, Bernt C; Christiansen, Dorte; Fure, Hilde; Castellheim, Albert; Nielsen, Erik Waage; Pharo, Anne Margrethe; Lindstad, Julie Katrine; Bergseth, Grete; Leslie, G; Lambris, John D.; Brandtzæg, Petter; Mollnes, Tom Eirik. (2011) Neisseria meningitidis and Escherichia coli are protected from leukocyte phagocytosis by binding to erythrocyte complement receptor 1 in human blood. Molecular Immunology. volum 48 (15-16).
  Academic article
• Chavez, Sherry A; Martinko, Alexander J; Lau, Corinna; Pham, Michael N; Cheng, Kui; Bevan, Douglas E; Mollnes, Tom Eirik; Yin, Hang. (2011) Development of beta-Amino Alcohol Derivatives That Inhibit Toll-like Receptor 4 Mediated Inflammatory Response as Potential Antiseptics. Journal of Medicinal Chemistry. volum 54 (13).
  Academic article
• Fure, Hilde; Landsem, A; Christiansen, Dorte; Brekke, Ole Lars; Nielsen, Erik Waage; Lambris, J.D.; Mollnes, Tom Eirik. (2011) C1 inhibitor efficiently inhibits Escherichia coli and LPS-induced tissue factor expression on monocytes and mRNA upregulation in human whole blood. Molecular Immunology. volum 48 (14).
  Summary/Abstract
• Grimnes, Gro; Beckman, Hans; Lappegård, Knut Tore; Mollnes, Tom Eirik; Skogen, Vegard. (2011) Recurrent meningococcal sepsis in a presumptive immunocompetent host shown to be complement C5 deficient-a case report. APMIS - Journal of Pathologiy, Microbiology and Immunology. volum 119 (7).
  Academic article
• Harboe, Morten; Thorgersen, Ebbe Billmann; Mollnes, Tom Eirik. (2011) Advances in assay of complement function and activation. Advanced Drug Delivery Reviews. volum 63 (12).
  Scientific translation/review
• Hellerud, Bernt C; Aase, Audun; Næss, Lisbeth Meyer; Nome, Lisa; Herstad, Tove Karin; Lappegaard, Knut Tore; Skogen, Vegard; Brandtzæg, Petter; Høiby, Ernst Arne; Mollnes, Tom Eirik. (2011) Vaccination of a C5-deficient man against Neisseria meningitidis: Effect on opsonophagocytosis and bacterial growth. Molecular Immunology. volum 48 (14).
  Summary/Abstract
• Hovland, Anders Wilhelm; Hardersen, Randolf; Enebakk, Terje; Mollnes, Tom Eirik; Lappegård, Knut Tore. (2011) Patient tolerance regarding different low-density lipoprotein apheresis columns: Frequent minor side effects and high patient satisfaction. Journal of Clinical Lipidology. volum 5 (1).
  Academic article
• Lau, Corinna; Nygård, Ståle; Fure, Hilde; Lappegård, Knut Tore; Brekke, Ole Lars; Hovig, Eivind; Mollnes, Tom Eirik. (2011) Challenging pattern recognition cross-talk: A gene profiling perspective of human Gram-negative bacteriaemia. Molecular Immunology. volum 48 (14).
  Summary/Abstract
• Ludviksen, Judith K; Bergseth, Grete; Nilsson, B.; Giclas, Patricia C.; Mollnes, Tom Eirik. (2011) Preparation of an international complement activation standard. Part two: Storage stability. Molecular Immunology. volum 48 (14).
  Summary/Abstract
• Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Strand, Berit Løkensgard; Skjåk-Bræk, Gudmund; Lacík, Igor; Espevik, Terje; Mollnes, Tom Eirik. (2011) Alginate microbeads are complement compatible, in contrast to polycation containing microcapsules, as revealed in a human whole blood model. Acta Biomaterialia. volum 7 (6).
  Academic article
• Sokolov, Andrey; Hellerud, Bernt C; Johannessen, Erik; Mollnes, Tom Eirik. (2011) Complement inhibition prevents granulocyte activation caused by candidate biomaterials for an implantable microfabricated device. Molecular Immunology. volum 48 (14).
  Summary/Abstract
• Sokolov, Andrey; Hellerud, Bernt C; Lambris, John D.; Johannessen, Erik; Mollnes, Tom Eirik. (2011) Activation of polymorphonuclear leukocytes by candidate biomaterials for an implantable glucose sensor. Journal of Diabetes Science and Technology. volum 5 (6).
  Academic article
• Sokolov, Andrey; Hellerud, Bernt C; Pharo, Anne; Johannessen, Erik A.; Mollnes, Tom E.. (2011) Complement activation by candidate biomaterials of an implantable microfabricated medical device. Journal of Biomedical Materials Research. Part B - Applied biomaterials. volum 98B (2).
  Academic article
• Søyland, Elisabeth; Heier, Ingvild; Rodríguez-Gallego, Carlos; Mollnes, Tom Eirik; Johansen, Finn Eirik; Holven, Kirsten Bjørklund; Halvorsen, Bente; Aukrust, Pål; Jahnsen, Frode Lars; de la Rosa-Carrillo, Daniel; Polesie, Anne Lene Krogstad; Nenseter, Marit Sofie. (2011) Sun exposure induces rapid immunological changes in skin and peripheral blood in patients with psoriasis. British Journal of Dermatology. volum 164 (2).
  Academic article
• Thiara, Amrit Paul Singh; Mollnes, Tom Eirik; Videm, Vibeke; Andersen, Vidar Ytterdal; Svennevig, Katja Christiane; Kolset, Svein Olav; Fiane, Arnt E. (2011) Biocompatibility and pathways of initial complement pathway activation with Phisio- and PMEA-coated cardiopulmonary bypass circuits during open-heart surgery. Perfusion. volum 26 (2).
  Academic article
• Torfoss, Dag; Sandstad, Berit; Mollnes, Tom Eirik; Høiby, Ernst Arne; Holte, Harald; Bjerner, Lars Johan; Bjøro, Trine; Gaudernack, Gustav; Kvalheim, Gunnar; Kvaløy, Stein Olav. (2011) The Mild Inflammatory Response in Febrile Neutropenic Lymphoma Patients with Low Risk of Complications is More Pronounced in Patients Receiving Tobramycin Once Daily Compared with Three Times Daily. Scandinavian Journal of Immunology. volum 74 (6).
  Academic article
• van Kuilenburg, Janet; Lappegård, Knut Tore; Sexton, Joseph; Plesiewicz, Izabela; Lap, Paul; Bouwels, Leon; Sprong, Tom; Mollnes, Tom Eirik; Verheugt, Freek; van Heerde, Waander L.; Pop, Gheorghe A.. (2011) Persisting thrombin activity in elderly patients with atrial fibrillation on oral anticoagulation is decreased by anti-inflammatory therapy with intensive cholesterol-lowering treatment. Journal of Clinical Lipidology. volum 5 (4).
  Academic article
• Wester, Torjus; Häggblad, Erik; Ahmed, Zaheer; Barratt-Due, Andreas; Kvernebo, Mari Skylstad; Halvorsen, Per Steinar; Mollnes, Tom Eirik; Kvernebo, Knut. (2011) Assessments of skin and tongue microcirculation reveals major changes in porcine sepsis. Clinical Physiology and Functional Imaging. volum 31 (2).
  Academic article

2010

• Barratt-Due, Andreas; Thorgersen, Ebbe Billmann; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Brekke, Ole Lars; Christiansen, Dorte; Lambris, John D.; Mollnes, Tom Eirik. (2010) Selective inhibition of TNF-alpha or IL-1 beta does not affect E. coli-induced inflammation in human whole blood. Molecular Immunology. volum 47 (9).
  Academic article
• Barratt-Due, Andreas; Thorgersen, Ebbe Billmann; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Nunn, Miles A.; Mollnes, Tom Eirik. (2010) Ornithodoros moubata complement inhibitor (OmCI)-A novel and efficient C5 inhibitor in the pig. Molecular Immunology. volum 47 (13).
  Summary/Abstract
• Christiansen, D; Brekke, Ole Lars; Stenvik, Jørgen; Lambris, JD; Espevik, Terje; Mollnes, Tom Eirik. (2010) Differential effect of inhibiting MD-2 and CD14 on LPS- versus whole E. coli bacteria-induced cytokine responses in human blood. Molecular Immunology. volum 47 (13).
  Summary/Abstract
• Dalen, Marit Lunde; Alme, Tomas Nordheim; Munkeby, Berit Holthe; Løberg, Else Marit; Pripp, Are Hugo; Mollnes, Tom Eirik; Rootwelt, Terje; Saugstad, Ola Didrik. (2010) Early protective effect of hypothermia in newborn pigs after hyperoxic, but not after normoxic, reoxygenation. Journal of Perinatal Medicine. volum 38 (5).
  Academic article
• Eagan, Tomas Mikal Lind; Aukrust, Pål; Bakke, Per S.; Damås, Jan Kristian; Skorge, Trude Duelien; Hardie, Jon Andrew; Ueland, Thor; Mollnes, Tom Eirik. (2010) Systemic mannose-binding lectin is not associated with chronic obstructive pulmonary disease. Respiratory Medicine. volum 104 (2).
  Academic article
• Eagan, Tomas Mikal Lind; Aukrust, Pål; Ueland, Thor; Hardie, Jon Andrew; Johannessen, Ane; Mollnes, Tom Eirik; Damås, Jan Kristian; Bakke, Per S.; Wagner, P.D.. (2010) Body composition and plasma levels of inflammatory biomarkers in COPD. European Respiratory Journal. volum 36 (5).
  Academic article
• Eagan, Tomas Mikal Lind; Damås, Jan Kristian; Ueland, Thor; Voll-Aanerud, Marianne; Mollnes, Tom Eirik; Hardie, Jon Andrew; Bakke, Per S.; Aukrust, Pål. (2010) Neutrophil Gelatinase-Associated Lipocalin A Biomarker in COPD. Chest. volum 138 (4).
  Academic article
• Eagan, Tomas Mikal Lind; Ueland, Thor; Wagner, Peter D.; Hardie, Jon Andrew; Mollnes, Tom Eirik; Damås, Jan Kristian; Aukrust, Pål; Bakke, Per S.. (2010) Systemic inflammatory markers in chronic obstructive pulmonary disease – results from the Bergen COPD Cohort Study. European Respiratory Journal. volum 35 (3).
  Academic article
• Eggum, Rune; Ueland, Thor; Mollnes, Tom Eirik; Videm, Vibeke; Fiane, Arnt E; Aukrust, Pål; Lindberg, Harald L. (2010) Perfusion temperature, thyroid horomones and inflammation during pediatric cardiac surgery. Interactive Cardiovascular and Thoracic Surgery. volum 10.
  Academic article
• Fure, Hilde; Brekke, Ole Lars; Lambris, J.D.; Mollnes, Tom Eirik. (2010) Key role of CD14 in the E. coli- and LPS-induced mRNA down regulation of the C5a receptors CD88 and C5L2. Molecular Immunology. volum 47 (13).
  Summary/Abstract
• Granslo, Hildegunn Norbakken; Klingenberg, Claus; Aarag, Elizabeth; Rønnestad, Arild Erlend; Mollnes, Tom Eirik; Flægstad, Trond. (2010) Arginine Catabolic Mobile Element Is Associated With Low Antibiotic Resistance and Low Pathogenicity in Staphylococcus epidermidis From Neonates. Pediatric Research. volum 68 (3).
  Academic article
• Haugaa, Håkon; Thorgersen, Ebbe Billmann; Foss, Aksel; Pharo, Anne Margrethe; Mollnes, Tom Eirik; Tønnessen, Tor Inge. (2010) Microdialysis Catheters in Liver Transplants Detect Rejection Prior to Biopsy. Liver transplantation. volum 16 (6).
  Summary/Abstract
• Hellerud, Bernt C; Nielsen, Erik Waage; Thorgersen, Ebbe Billmann; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Tønnessen, Tor Inge; Castellheim, Albert; Mollnes, Tom Eirik; Brandtzæg, Petter. (2010) Dissecting the effects of lipopolysaccharides from nonlipopolysaccharide molecules in experimental porcine meningococcal sepsis. Critical Care Medicine. volum 38 (6).
  Academic article
• Hellerud, Bernt Christian; Aase, Audun; Herstad, Tove Karin; Næss, Lisbeth Meyer; Kristiansen, Lisa Høyem; Siebke, Anne-Marie; Harboe, Morten; Lappegård, Knut Tore; Brandtzæg, Petter; Høiby, Ernst Arne; Mollnes, Tom Eirik. (2010) Critical roles of complement and antibodies in host defense mechanisms against Neisseria meningitidis as revealed by human complement genetic deficiencies. Infection and Immunity. volum 78 (2).
  Academic article
• Hovland, Anders Wilhelm; Hardersen, Randolf; Mollnes, Tom Eirik; Lappegård, Knut Tore. (2010) Selective Whole Blood Lipoprotein Apheresis to prevent Pancreatitis in Drug Refractory Hypertriglyceridemia. JOP. Journal of the Pancreas. volum 11 (6).
  Academic article
• Hovland, Anders Wilhelm; Hardersen, Randolf; Nielsen, Erik Waage; Mollnes, Tom Eirik; Lappegård, Knut Tore. (2010) Hematologic and Hemostatic Changes Induced by Different Columns During LDL Apheresis. Journal of clinical apheresis. volum 25 (5).
  Academic article
• Husebye, Harald; Aune, Marie Hjelmseth; Stenvik, Jørgen; Samstad, Eivind Ottersen; Skjeldal, Frode Miltzow; Halaas, Øyvind; Nilsen, Nadra; Stenmark, Harald Alfred; Latz, Eicke; Lien, Egil; Mollnes, Tom Eirik; Bakke, Oddmund; Espevik, Terje. (2010) The Rab11a GTPase Controls Toll-like Receptor 4-Induced Activation of Interferon Regulatory Factor-3 on Phagosomes. Immunity. volum 33 (4).
  Academic article
• Johannessen, Erik; Krushinitskaya, Olga; Sokolov, Andrey; Häfliger, Philipp; Hoogerwerf, Arno; Hinderling, Christian; Kautio, Kari; Lenkkeri, Jaakko; Strömmer, Esko; Kondratyev, Vasily; Tønnessen, Tor Inge; Mollnes, Tom Eirik; Jakobsen, Henrik; Zimmer, Even; Akselsen, Bengt. (2010) Toward an injectable continuous osmotic glucose sensor. Journal of Diabetes Science and Technology. volum 4 (4).
  Academic article
• Kourtzelis, Ioannis; Markiewski, MM; Doumas, Michael; Rafail, Stavros; Kambas, Konstantinos; Mitroulis, Ioannis; Panagoutsos, Stelios; Passadakis, Ploumis; Vargemezis, Vasilios; Magotti, P; Qu, Hongchang; Mollnes, Tom Eirik; Ritis, Konstantinos; Lambris, John D.. (2010) Complement anaphylatoxin C5a contributes to hemodialysis-associated thrombosis. Molecular Immunology. volum 47 (13).
  Summary/Abstract
• Kourtzelis, Ioannis; Markiewski, MM; Doumas, Michael; Rafail, Stavros; Kambas, Konstantinos; Mitroulis, Ioannis; Panagoutsos, Stelios; Passadakis, Ploumis; Vargemezis, Vasilios; Magotti, P; Qu, Hongchang; Mollnes, Tom Eirik; Ritis, Konstantinos; Lambris, John D.. (2010) Complement anaphylatoxin C5a contributes to hemodialysis-associated thrombosis. Blood. volum 116 (4).
  Academic article
• Ludviksen, J.K.; Hennø, L.T.; Brekke, O.L.; Christiansen, D.; Fure, H.; Nielsen, EW; Mollnes, Tom Eirik. (2010) Elevated cytokine concentrations in serum compared to plasma samples from healthy humans is not explained by in vitro complement activation. Molecular Immunology. volum 47 (13).
  Summary/Abstract
• Lupu, Florea; Silasi-Mansat, R; Zhu, H; Popescu, NI; Peer, G; Sfyroera, G; Magotti, P; Ivanciu, L; Lupu, C; Mollnes, Tom Eirik; Taylor, FB; Kinasewitz, G; Lambris, JD. (2010) Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of E. coil sepsis. Molecular Immunology. volum 47 (13).
  Summary/Abstract
• Mollnes, Tom Eirik; Hoedemaekers, C; van Deuren, M; Sprong, T; Pickkers, P; Klasen, I; van der Hoeven, J. (2010) The Complement System Is Activated in a Biphasic Pattern After Coronary Artery Bypass Grafting. Annals of Thoracic Surgery. volum 89 (3).
  Academic article
• Salvesen, Bodil; Stenvik, Jørgen; Rosetti, Carlo; Saugstad, Ola D; Espevik, Terje; Mollnes, Tom E.. (2010) Meconium-induced release of cytokines is mediated by the TRL4/MD-2 complex in a CD14-dependent manner. Molecular Immunology. volum 47 (6).
  Academic article
• Silasi-Mansat, Robert; Zhu, H; Popescu, Narcis I.; Peer, Glenn; Sfyroera, G; Magotti, P; Ivanciu, Lacramioara; Lupu, Cristina; Mollnes, Tom Eirik; Taylor, FB; Kinasewitz, Gary; Lambris, John D.; Lupu, F. (2010) Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of Escherichia coli sepsis. Blood. volum 116 (6).
  Academic article
• Sokolov, Andrey; Hellerud, Bernt C; Pharo, Anne Margrethe; Johannessen, Erik; Mollnes, Tom Eirik. (2010) Biocompatibility of candidate materials for an implantable glucose sensor in terms of complement and neutrophil activating properties. Molecular Immunology. volum 47 (13).
  Summary/Abstract
• Thiara, AS; Andersen, VY; Videm, V; Mollnes, Tom Eirik; Svennevig, K; Nilsen-Hoel, Tom; Fiane, AE. (2010) Comparable biocompatibility of Phisio- and Bioline-coated cardiopulmonary bypass circuits indicated by the inflammatory response. Perfusion. volum 25 (1).
  Academic article
• Thorgersen, Ebbe Billmann; Hellerud, Bernt C; Nielsen, Erik Waage; Barratt-Due, Andreas; Fure, Hilde; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Fosse, Erik; Tønnessen, Tor Inge; Johansen, Harald Thidemann; Castellheim, Albert; Mollnes, Tom Eirik. (2010) CD14 inhibition efficiently attenuates early inflammatory and hemostatic responses in Escherichia coli sepsis in pigs. The FASEB Journal. volum 24 (3).
  Academic article
• Thorgersen, Ebbe Billmann; Hellerud, Bernt C; Nielsen, Erik Waage; Barratt-Due, Andreas; Fure, Hilde; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Fosse, Erik; Tønnessen, Tor Inge; Johansen, Harald Thidemann; Castellheim, Albert; Mollnes, Tom Eirik. (2010) Upstream inhibition of key innate immune pathways in vivo in sepsis. Molecular Immunology. volum 47 (13).
  Summary/Abstract
• Thorgersen, Ebbe Billmann; Ludviksen, Judith K; Lambris, John D.; Sfyroera, G; Nielsen, Erik Waage; Mollnes, Tom Eirik. (2010) Anti-inflammatory effects of C1-Inhibitor in porcine and human whole blood are independent of its protease inhibition activity. Innate Immunity. volum 16 (4).
  Academic article
• Wester, Torjus; Häggblad, Erik; Ahmed, Zaheer; Barratt-Due, Andreas; Kvernebo, Mari Skylstad; Halvorsen, Per Steinar; Mollnes, Tom Eirik; Kvernebo, Knut. (2010) Assessments of skin and tongue microcirculation reveals major changes in porcine sepsis. Clinical Physiology and Functional Imaging.
  Academic article

2009

• Lappegård, KT; Lappegård, Knut Tore; Lappegård, Knut Tore; Christiansen, Dorte; Christensen, D; Pharo, Anne; Thorgersen, Ebbe Billmann; Hellerud, Bernt Christian; Lindstad, Julie; Nielsen, Erik Waage; Bergseth, Grethe; Fadnes, Dag; Abrahamsen, Tore G; Høiby, Ernst Arne; Schejbel, L; Schejbel, Lone; Garred, Peter; Garred, P; Lambris, John D; Lambris, JD; Harboe, Morten; Mollnes, Tom Eirik. (2009) Human genetic deficiencies reveal the roles of complement in the inflammatory network: Lessons from nature. Proceedings of the National Academy of Sciences of the United States of America. volum 106 (37).
  Academic article
• Barratt-Due, A*; Thorgersen, EB; Lindstad, J; Pharo, A; Brekke, OL; Christiansen, D; Lambris, JD; Mollnes, Tom Eirik. (2009) Selective inhibition of TNF-α and IL-1β do not affect E.coli-induced inflammation in human whole blood, in contrast to combined complement- and CD14-inhibition. Molecular Immunology. volum 46.
  Summary/Abstract
• Bexborn, Fredrik; Engberg, Anna E.; Sandholm, Kerstin; Mollnes, Tom Eirik; Hong, Jaan; Ekdahl, Kristina N.. (2009) Hirudin versus heparin for use in whole blood in vitro biocompatibility models. Journal of Biomedical Materials Research. Part A. volum 89A (4).
  Academic article
• Brekke, Ole Lars; Hellerud, BC; Christiansen, Dorte; Fure, Hilde; Bergseth, G; Bergseth, Grethe; Leslie, G; Lambris, J; Mollnes, Tom Eirik. (2009) Key role of complement receptor 1 in the initial binding of Escherichia coli and Neisseria meningitidis to erythrocytes in human whole blood. Molecular Immunology. volum 46 (14).
  Summary/Abstract
• Castellheim, A; Brekke, Ole Lars; Espevik, T; Harboe, M; Harboe, M; Mollnes, Tom Eirik. (2009) Innate Immune Responses to Danger Signals in Systemic Inflammatory Response Syndrome and Sepsis. Scandinavian Journal of Immunology. volum 69 (6).
  Scientific translation/review
• Corallini, Federica; Bossi, Fleur; Gonelli, Arianna; Tripodo, Claudio; Castellino, Gabriella; Mollnes, Tom Eirik; Tedesco, Francesco; Rizzi, Lucia; Trotta, Francesco; Zauli, Giorgio; Secchiero, Paola. (2009) The soluble terminal complement complex (SC5b-9) up-regulates osteoprotegerin expression and release by endothelial cells: implications in rheumatoid arthritis. Rheumatology. volum 48 (3).
  Academic article
• Dalen, Marit Lunde; Ellingsrud, Elisabeth; Saugstad, Ola Didrik; Mollnes, Tom Eirik; Rootwelt, Terje. (2009) Post-hypoxic hypothermia is protective in human NT2-N neurons regardless of oxygen concentration during reoxygenation. Brain Research. volum 1259.
  Academic article
• Eagan, Tomas Mikal Lind; Aukrust, Pål; Bakke, Per S.; Damås, Jan Kristian; Skorge, Trude Duelien; Hardie, Jon Andrew; Ueland, Thor; Mollnes, Tom Eirik. (2009) Systemic mannose-binding lectin is not associated with chronic obstructive pulmonary disease. Respiratory Medicine. volum 104 (2).
  Academic article
• Harboe, Morten; Garred, P; Karlstrøm, Ellen; Lindstad, Julie Katrine; Stahl, GL; Mollnes, Tom Eirik. (2009) The down-stream effects of mannan-induced lectin complement pathway activation depend quantitatively on alternative pathway amplification. Molecular Immunology. volum 47 (2-3).
  Academic article
• Hellerud, Bernt C; Olstad, Ole Kristoffer; Brandtzæg, Petter; Mollnes, Tom Eirik. (2009) Transcription of key components of complement and the TLR-signaling system is down-regulated by LPS in a porcine model of meningococcal sepsis. Molecular Immunology. volum 46 (14).
  Summary/Abstract
• Hoel, TN; Nilsen-Hoel, Tom; Thiara, AS; Videm, Vibeke; Fiane, AE; Mollnes, TE; Castellheim, A; Svennevig, JL. (2009) In vitro evaluation of PHISIO-coated sets for pediatric cardiac surgery. Scandinavian Cardiovascular Journal. volum 43 (2).
  Academic article
• Hovland, Anders; Hardersen, Randolf; Randolf, Hardersen; Sexton, Joe; Mollnes, Tom Eirik; Lappegård, Knut Tore. (2009) Different Inflammatory Responses Induced by Three LDL-Lowering Apheresis Columns. Journal of clinical apheresis. volum 24 (6).
  Academic article
• Kasin, JI; Kjekshus, John; Aukrust, Pål; Mollnes, Tom Eirik; Wagstaff, A. S.. (2009) A helicopter flight does not induce significant changes in systemic biomarker profiles. Scandinavian Journal of Clinical and Laboratory Investigation. volum 69 (4).
  Academic article
• Macor, Paolo; De Maso, Luca; Nilsen-Hoel, Tom; Fiane, Arnt E; Mollnes, Tom Eirik; Tedesco, Francesco. (2009) Analysis of the complement system in human lymph. Molecular Immunology. volum 46 (14).
  Summary/Abstract
• Manderson, GA; Martin, M; Onnerfjord, P; Saxne, T; Schmidtchen, A; Mollnes, Tom Eirik; Heinegard, D; Blom, AM. (2009) Interactions of histidine-rich glycoprotein with immunoglobulins and proteins of the complement system. Molecular Immunology. volum 46 (16).
  Academic article
• Martin, M; Gottsater, A; Nilsson, PM; Mollnes, Tom Eirik; Lindblad, B; Blom, AM. (2009) Complement activation and plasma levels of C4b-binding protein in critical limb ischemia patients. Journal of Vascular Surgery. volum 50 (1).
  Academic article
• Natvig, Jacob B; Mollnes, Tom Eirik. (2009) Professor emeritus Morten Harboe, one of the founders of Scandinavian Journal of Immunology, turns 80. Scandinavian Journal of Immunology. volum 69 (6).
  Editorial
• Nielsen, Erik Waage; Hellerud, BC; Thorgersen, Ebbe B; Castellheim, A; Pharo, A; Lindstad, Julie; Tonnessen, Tor Inge; Tønnessen, Tor Inge; Brandtzæg, Petter; Mollnes, Tom Eirik. (2009) A NEW DYNAMIC PORCINE MODEL OF MENINGOCOCCAL SHOCK. Shock. volum 32 (3).
  Academic article
• Pedersen, Elena Didenko; Løberg, Else Marit; Vege, E; Daha, MR; Mæhlen, Jan; Mollnes, Tom Eirik. (2009) In Situ Deposition of Complement in Human Acute Brain Ischaemia. Scandinavian Journal of Immunology. volum 69 (6).
  Academic article
• Salvesen, B; Salvesen, Bodil; Nielsen, Erik Waage; Harboe, M; Saugstad, OD; Mollnes, Tom Erik. (2009) Mechanisms of complement activation and effects of C1-inhibitor on the meconium-induced inflammatory reaction in human cord blood. Molecular Immunology. volum 46 (4).
  Academic article
• Salvesen, Bodil; Mollnes, Tom Eirik. (2009) Pathway-specific complement activity in pigs evaluated with a human functional complement assay. Molecular Immunology. volum 46 (8-9).
  Academic article
• Salvesen, Bodil; Rossetti, Carlo; Mollnes, Tom Eirik. (2009) Mechanisms of meconium-induced innate immune-reactions: Role of complement and CD14/TLR4/MD-2. Molecular Immunology. volum 46 (14).
  Summary/Abstract
• Siezenga, MA; Shaw, PKC; van der Geest, RN; Mollnes, Tom Eirik; Daha, MR; Rabelink, TJ; Berger, SP. (2009) Enhanced complement activation is part of the unfavourable cardiovascular risk profile in South Asians. Clinical and Experimental Immunology. volum 157 (1).
  Academic article
• Sikkeland, Liv Ingunn Bjoner; Eduard, W; Larsen, Astrid Marie; Thorgersen, Ebbe Billmann; Haug, T.; Aukrust, Pål; Halvorsen, Bente; Mollnes, Tom Eirik; Kongerud, Johny. (2009) Occupational exposure to bacterial single cell protein induces inflammation in lung and blood. Inhalation Toxicology. volum 21 (8-11).
  Academic article
• Sokolov, Andrey; Hellerud, Bernt C; Pharo, Anne Margrethe; Johannessen, Erik; Mollnes, Tom Eirik. (2009) Complement activation by proposed biomaterials intended for composition of a glucose sensor. Molecular Immunology. volum 46 (14).
  Summary/Abstract
• Sprong, Tom; Mollnes, Tom Eirik; Neeleman, Chris; Swinkels, Dorine; Netea, Mihai G.; van der Meer, Jan W.M.; van Deuren, Marcel. (2009) Mannose-Binding Lectin Is a Critical Factor in Systemic Complement Activation during Meningococcal Septic Shock. Clinical Infectious Diseases. volum 49 (9).
  Academic article
• Thorgersen, Ebbe Billmann; Pharo, Anne Margrethe; Haverson, K; Axelsen, Anne Kilsund; Gaustad, Peter; Kotwal, GJ; Sfyroera, G; Mollnes, Tom Eirik. (2009) Inhibition of Complement and CD14 Attenuates the Escherichia coli-Induced Inflammatory Response in Porcine Whole Blood. Infection and Immunity. volum 77 (2).
  Academic article
• Ørn, Stein; Breland, Unni M.; Mollnes, Tom Eirik; Manhenke, Cord Arend; Dickstein, Kenneth; Aukrust, Pål; Ueland, Thor. (2009) The Chemokine Network in Relation to Infarct Size and Left Ventricular Remodeling Following Acute Myocardial Infarction. American Journal of Cardiology. volum 104 (9).
  Academic article
• Ørn, Stein; Orn, S; Manhenke, Cord Arend; Ueland, Thor; Damås, Jan Kristian; Mollnes, Tom Eirik; Edvardsen, Thor; Aukrust, Pål; Dickstein, Kenneth. (2009) C-reactive protein, infarct size, microvascular obstruction, and left-ventricular remodelling following acute myocardial infarction. European Heart Journal. volum 30 (10).
  Academic article

2008

• Bergseth, Grete; Lambris, JD; Lappegård, Knut Tore; Mollnes, Tom Eirik. (2008) The dependence of C5 on artificial surface-induced inflammatory reactions: Evidence from a C5-deficient individual. Molecular Immunology. volum 45.
  Summary/Abstract
• Brekke, Ole Lars; Christiansen, D; Fure, H; Pharo, A; Fung, M; Riesenfeld, J; Mollnes, Tom Eirik. (2008) Combined inhibition of complement and CD14 abolish E-coli-induced cytokine-, chemokine- and growth factor-synthesis in human whole blood. Molecular Immunology. volum 45.
  Academic article
• Brekke, Ole Lars; CHRISTIANSEN, DANIELA; Christiansen, D; Hellerud, BC; Fure, H; Bergseth, Grete; Leslie, G; Lambris, JD; Lambris, J; Mollnes, Tom Eirik. (2008) Key role of complement receptor 1 in the initial binding of Escherichia coli and Neisseria meningitidis to erythrocytes in human whole blood. Molecular Immunology. volum 45 (16).
  Summary/Abstract
• Castellheim, A; Nilsen-Hoel, Tom; Hoel, TN; Videm, Vibeke; Fosse, E; Fosse, E; Pharo, A; Svennevig, JL; Fiane, AE; Mollnes, TE. (2008) Biomarker profile in off-pump and on-pump coronary artery bypass grafting surgery in low-risk patients. Annals of Thoracic Surgery. volum 85 (6).
  Academic article
• Castellheim, A; Thorgersen, EB; Hellerud, BC; Pharo, A; Johansen, HT; Brosstad, F; Gaustad, P; Brun, H; Fosse, E; Tønnessen, Tor Inge; Tonnessen, TI; Nielsen, Erik Waage; Mollnes, Tom Erik. (2008) New biomarkers in an acute model of live Escherichia coli-induced sepsis in pigs. Scandinavian Journal of Immunology. volum 68.
  Academic article
• Eggum, R; Ueland, T; Mollnes, TE; Videm, Vibeke; Aukrust, P; Fiane, AE; Lindberg, HL. (2008) Effect of perfusion temperature on the inflammatory response during pediatric cardiac surgery. Annals of Thoracic Surgery. volum 85 (2).
  Academic article
• Harboe, Morten; Mollnes, Tom Eirik. (2008) The alternative complement pathway revisited. Journal of Cellular and Molecular Medicine. volum 12.
  Scientific translation/review
• Hellerud, BC; Stenvik, Jørgen; Espevik, Terje; Lambris, JD; Mollnes, TE; Brandtzæg, Petter. (2008) Stages of meningococcal sepsis simulated in vitro, with emphasis on complement and Toll-like receptor activation. Infection and Immunity. volum 76 (9).
  Academic article
• Hellerud, BC; Stenvik, Jørgen; Espevik, Terje; Lambris, John D.; Mollnes, Tom Eirik; Brandtzaeg, P. (2008) Stages of meningococcal sepsis stimulated in vitro, with emphasis on complement and Toll-like receptor activation. Infection and Immunity. volum 76 (9).
  Academic article
• Lappegard, KT; Bergseth, G; Riesenfeld, J; Pharo, Anne Margrethe; Magotti, P; Lambris, JD; Mollnes, Tom Eirik. (2008) The artificial surface-induced whole blood inflammatory reaction revealed by increases in a series of chemokines and growth factors is largely complement dependent. Journal of Biomedical Materials Research. Part A. volum 87A.
  Academic article
• Lappegard, KT; CHRISTIANSEN, DANIELA; Pharo, Anne Margrethe; Thorgersen, Ebbe Billmann; Hellerud, Bernt C; Lindstad, Julie Katrine; Nielsen, Erik Waage; Bergseth, G; Fadnes, D; Abrahamsen, T; Hoiby, A; Schejbel, L; Garred, P; Lambris, JD; Harboe, Morten; Mollnes, Tom Eirik. (2008) Genetic complement deficiencies dissociate the roles of human complement in the inflammatory responses: Lessons from nature. Molecular Immunology. volum 45 (16).
  Summary/Abstract
• Magotti, P; Ricklina, D; Sfyroera, G; Qu, Hong; Mollnes, Tom Eirik; Lupu, F; Taylor, FB; Lambris, JD. (2008) A C3 inhibitor on its way to clinical applications: Novel developments in compstatin activity and function. Molecular Immunology. volum 45 (16).
  Summary/Abstract
• Martin, M; Gottsater, A; Nilsson, PM; Mollnes, Tom Eirik; Lindblad, B; Blom, AM. (2008) Complement activation and plasma levels of C4b-binding protein in critical limb ischaemia patients. Molecular Immunology. volum 45 (16).
  Summary/Abstract
• Mollnes, Tom Eirik. (2008) High mobility group box-1 protein - one step closer to the clinic?. Critical Care Medicine. volum 12.
  Short communication
• Mollnes, Tom Eirik. (2008) High mobility group box-1 protein - one step closer to the clinic?. Critical Care. volum 12 (4).
  Editorial
• Mollnes, Tom Eirik. (2008) High mobility group complex-1 protein (HMGB1) - one step closer to the clinic?. Critical Care. volum 12.
  Letter to the editor
• Mollnes, Tom Eirik; Castellheim, Albert; Lindenskov, Paal Helge H.; Salvesen, Bodil; Saugstad, Ola Didrik. (2008) The role of complement in meconium aspiration syndrome. Journal of Perinatology. volum 28.
  Academic article
• Mollnes, Tom Eirik; Christiansen, D; Brekke, Ole Lars; Espevik, T. (2008) Hypothesis: Combined inhibition of complement and CD14 as treatment regimen to attenuate the inflammatory response. Advances in Experimental Medicine and Biology. volum 632.
  Academic article
• Mollnes, Tom Eirik; Mahmoudi, Maryam; Roos, D. (2008) Complement Deficiencies. Primary Immunodeficiency Diseases.
  Chapter
• Risnes, Ivar; Wagner, Kari; Ueland, Thor; Mollnes, Tom Eirik; Aukrust, Pål; Svennevig, Jan Ludvig. (2008) Interleukin-6 may predict survival in extracorporeal membrane oxygenation treatment. Perfusion. volum 23 (3).
  Academic article
• Sagedal, Solbjørg; Thiel, Steffen; Hansen, Troels Krarup; Mollnes, Tom Eirik; Rollag, Halvor; Hartmann, Anders. (2008) Impact of the complement lectin pathway on cytomegalovirus disease early after kidney transplantation. Nephrology, Dialysis and Transplantation. volum 23 (12).
  Academic article
• Salvesen, Bodil; Fung, M; Saugstad, Ola Didrik; Mollnes, Tom Eirik. (2008) Role of complement and CD14 in meconium-induced cytokine formation. Pediatrics. volum 121.
  Academic article
• Salvesen, Bodil; Mollnes, Tom Eirik; Saugstad, Ola Didrik. (2008) Albumin lavage does not improve the outcome of meconium aspiration syndrome. Journal of Maternal-Fetal & Neonatal Medicine. volum 21 (10).
  Academic article
• Salvesen, Bodil; Nielsen, Erik Waage; Harboe, Morten; Saugstad, Ola Didrik; Mollnes, Tom Eirik. (2008) Mechanisms of complement activation and effects of C1-inhibitor on the meconium-induced inflammatory reaction in cord blood. Molecular Immunology. volum 45 (16).
  Summary/Abstract
• Salvesen, Bodil; Nielsen, Erik Waage; Saugstad, Ola Didrik; Mollnes, Tom Eirik. (2008) C1-inhibitor in meconium-induced complement activation and cytokine formation. Neonatology. volum 93.
  Summary/Abstract
• Svennevig, Katja Christiane; Nilsen-Hoel, Tom; Thiara, Amrit Singh; Kolset, Svein Olav; Castellheim, Albert; Mollnes, Tom Eirik; Brosstad, Frank Roger; Fosse, Erik; Svennevig, Jan Ludvig. (2008) Syndecan-1 plasma levels during coronary artery bypass surgery with and without cardiopulmonary bypass. Perfusion. volum 23 (3).
  Academic article
• Sæthre, Marit; Schneider, MKJ; Lambris, JD; Magotti, P; Haraldsen, Guttorm; Seebach, JD; Mollnes, Tom Eirik. (2008) Cytokine secretion depends on Gal alpha(1,3)Gal expression in a pig-to-human whole blood model. Journal of Immunology. volum 180.
  Academic article
• Thorgersen, Ebbe Billmann; Macagno, A; Rossetti, C; Mollnes, Tom Eirik. (2008) Cyanobacterial LPS antagonist (CyP) - A novel and efficient inhibitor of Escherichia coli LPS-induced cytokine response in the pig. Molecular Immunology. volum 45.
  Academic article
• Tripodo, C; Noris, M; Macor, P; Gastoldi, S; Pickering, M; Botto, M; Wurzner, R; Mollnes, Tom Eirik; Remuzzi, G; Tedesco, F. (2008) Is local complement activation involved in renal damage in patients with atypical haemolytic uraemic syndrome?. Molecular Immunology. volum 45 (16).
  Summary/Abstract
• Wælgaard, Lars Torbjørn; Thorgersen, Ebbe Billmann; Line, Pål Dag; Foss, Aksel; Mollnes, Tom Eirik; Tønnessen, Tor Inge. (2008) Microdialysis Monitoring of Liver Grafts by Metabolic Parameters, Cytokine Production, and Complement Activation. Transplantation. volum 86 (8).
  Academic article
• Åsberg, A.E.; Åsberg, Ann E.; Mollnes, Tom Eirik; Videm, V. (2008) Complement activation by neutrophil granulocytes. Scandinavian Journal of Immunology. volum 67.
  Academic article

2007

• Brekke, Ole Lars; Christiansen, D; Fure, H; Fung, M; Mollnes, Tom Eirik. (2007) Inhibition of complement and CD14 efficiently inhibits a broad panel of E-coli-induced inflammatory reactions in human whole blood. Molecular Immunology. volum 44.
  Summary/Abstract
• Brekke, Ole Lars; Christiansen, Dorte; Fure, Hilde; Fung, Michael; Mollnes, Tom Erik. (2007) The role of complement C3 opsonization, C5a receptor, and CD14 in E. coli-induced up-regulation of granulocyte and monocyte CD11b/CD18 (CR3), phagocytosis, and oxidative burst in human. Journal of Leukocyte Biology. volum 81.
  Academic article
• Christiansen, Dorte; Brekke, Ole Lars; Fure, Hilde; Fung, Michael; Mollnes, Tom Eirik. (2007) Inhibition of complement and CD14 abolishes E-coli-induced cytokine gene upregulation and protein synthesis. Molecular Immunology. volum 44.
  Summary/Abstract
• Hellerud, Bernt C; Thorgersen, Ebbe Billmann; Castellheim, Albert; Nielsen, EW; Pharo, Anne Margrethe; Lindstad, Julie Katrine; Fosse, Erik; Tønnessen, Tor Inge; Brandtzaeg, P; Mollnes, Tom Eirik. (2007) The role of complement and CD14 in the Gram-negative bacteria induced inflammatory reaction: In vitro evidence and design of an in vivo porcine model. Molecular Immunology. volum 44.
  Summary/Abstract
• Hellerud, Bernt Christian; Høiby, Ernst Arne; Lappegård, Knut Tore; Fure, Hilde; Brandtzæg, Petter; Harboe, Morten; Mollnes, Tom Eirik. (2007) Human genetic complement deficiencies reveal a critical role for C5/C5a in the phagocytosis and killing of Neisseria meningitidis and Escherichia coli in whole blood. Molecular Immunology. volum 44 (16).
  Summary/Abstract
• Hoel, TN; Videm, Vibeke; Mollnes, Tom Eirik; Saatvedt, K; Saatvedt, TE; Brosstad, F; Fiane, AE; Fosse, E; Svennevig, JL. (2007) Off-pump cardiac surgery abolishes complement activation. Perfusion. volum 22 (4).
  Academic article
• Lappegard, KT; Christiansen, D; Fadnes, D; Abrahamsen, T; Salvesen, B; Lambrise, JD; Mollnes, Tom Eirik. (2007) Complement is essential for phenotypic shift of leukocytes to a pro-inflammatory and pro-thrombotic state in a whole blood model of sepsis: Evidence from genetically complement-deficient patients. Molecular Immunology. volum 44.
  Summary/Abstract
• Lappegård, Knut Tore; Christiansen, D; Fadnes, D; Abrahamsen, T; Salvesen, B; Lambris, JD; Mollnes, Tom Eirik. (2007) Complement is essential for phenotypic shift of leukocytes to a proinflammatory and pro-thromobotic state in a whole blood model of sepsis: Evidence from genetically complement-deficient patients. Molecular Immunology. volum 44.
  Summary/Abstract
• Markiewski, MM; Nilsson, B; Ekdahl, KN; Mollnes, Tom Eirik; Lambris, JD; Lambris, JD. (2007) Complement and coagulation: strangers or partners in crime?. Trends in immunology. volum 28.
  Scientific translation/review
• Mollnes, Tom Eirik; Jokiranta, TS; Truedsson, L; Nilsson, B; Rodriguez de Cordoba, S; Kirschfink, M. (2007) Complement analysis in the 21st century. Molecular Immunology. volum 44.
  Academic article
• Nielsen, Erik Waage; Waage, Cristian; Fure, Hilde; Brekke, Ole Lars; Sfyroera, Georgia; Lambris, John D.; Lambris, JD; Mollnes, Tom Eirik. (2007) Effect of supraphysiologic levels of C1-inhibitor on the classical, lectin and alternative pathways of complement. Molecular Immunology. volum 44.
  Academic article
• Nilsson, B; Ekdahl, KN; Mollnes, Tom Eirik; Lambris, JD. (2007) The role of complement in biomaterial-induced inflammation. Molecular Immunology. volum 44.
  Academic article
• Pedersen, Elena Didenko; Aass, Hans Christian; Rootwelt, Terje; Fung, M.; Lambris, J.D.; Mollnes, Tom Eirik. (2007) CD59 Efficiently Protects Human NT2-N Neurons Against Complement-mediated Damage. Scandinavian Journal of Immunology. volum 66 (2).
  Academic article
• Pedersen, Elena Didenko; Ellingsrud, Elisabeth; Kvissel, Anne Katrine; Pharo, Anne Margrethe; Skålhegg, Bjørn Steen; Rootwelt, Terje; Mollnes, Tom Eirik. (2007) Expression of complement regulators and receptors on human NT2-N neurons - Effect of hypoxia and reoxygenation. Molecular Immunology. volum 44 (9).
  Academic article
• Roestenberg, M; McCall, M; Mollnes, Tom Eirik; van Deuren, M; Sprong, T; Klasen, I; Hermsen, CC; Sauerwein, RW; van der Ven, A. (2007) Complement activation in experimental human malaria infection. Transactions of the Royal Society of Tropical Medicine and Hygiene. volum 101.
  Academic article
• Salvesen, Bodil; Fung, Michael; Saugstad, Ola Didrik; Mollnes, Tom Eirik. (2007) The Role of Complement and CD14 in Meconium-Induced Cytokine Production. Molecular Immunology. volum 44 (16).
  Summary/Abstract
• Sikkeland, LIB; Thorgersen, EB; Haug, T; Mollnes, Tom Eirik. (2007) Complement activation and cytokine response by BioProtein, a bacterial single cell protein. Clinical and Experimental Immunology. volum 148.
  Academic article
• Sæthre, Marit; Baumann, BC; Fung, M; Seebach, JD; Mollnes, Tom Eirik. (2007) Characterization of natural human anti-non-Gal antibodies and their effect on activation of porcine gal-deficient endothelial cells. Transplantation. volum 84.
  Academic article
• Thorgersen, EB; Pharo, A; Lindstad, JK; Bergseth, G; Nielsen, EW; Lappegård, Knut Tore; Mollnes, Tom Eirik. (2007) Oxidative burst in complement deficient patients: Lessions from nature. Molecular Immunology. volum 44.
  Summary/Abstract
• Thorgersen, Ebbe B; Ghebremariam, Yohannes T; Nielsen, Erik Waage; Kotwal, Girish J; Mollnes, Tom Erik. (2007) Vaccinia virus complement control protein (VCP) is an efficient inhibitor of porcine complement. Molecular Immunology. volum 44.
  Summary/Abstract
• Thorgersen, Ebbe B; Ghebremariam, Yohannes T; Thurman, Joshua M; Fung, Michael; Nielsen, Erik Waage; Holers, V Michael; Kotwal, Girish J; Mollnes, Tom Erik. (2007) Candidate inhibitors of porcine complement. Molecular Immunology. volum 44.
  Academic article
• Waage, C; Nielsen, Erik Waage; Fure, H; Brekke, Ole Lars; Sfyroera, G; Lambris, JD; Lambris, JD; Mollnes, Tom Eirik. (2007) Effect of supraphysioloogic levels of C1-inhibitor on the classical, lectin, and alternative pathways of complement. Molecular Immunology. volum 44.
  Summary/Abstract
• Waage, C; Nielsen, EW; Fure, H; Brekke, Ole Lars; Sfyroera, G; Lambris, JD; Mollnes, Tom Eirik. (2007) Effect of supraphysiologic levels of C1-inhibitor on the classical, lectin and alternative pathways of complement. Molecular Immunology. volum 44.
  Summary/Abstract

2006

• Drogset, JO; Grontvedt, T; Jessen, V; Tegnander, A; Mollnes, Tom Eirik; Bergh, K. (2006) Comparison of in vitro and in vivo complement activation by metal and bioabsorbable screws used in anterior cruciate ligament reconstruction. Arthroscopy: The Journal of Arthroscopy And Related. volum 22.
  Academic article
• Frøyland, Elisabeth; Pedersen, Elena Didenko; Kvissel, Anne Katrine; Almaas, R; Pharo, Anne Margrethe; Skålhegg, Bjørn Steen; Mollnes, Tom Eirik; Rootwelt, T. (2006) Effect of acidosis on IL-8 and MCP-1 during hypoxia and reoxygenation in human NT2-N neurons. Brain Research. volum 1113.
  Academic article
• Harboe, Morten; Garred, P; Borgen, MS; Stahl, GL; Roos, A; Mollnes, Tom Eirik. (2006) Design of a complement mannose-binding lectin pathway-specific activation system applicable at low serum dilutions. Clinical and Experimental Immunology. volum 144.
  Academic article
• Sprong, T; Roos, D; Weemaes, C; Neeleman, C; Geesing, CLM; Mollnes, Tom Eirik; van Deuren, M. (2006) Deficient alternative complement pathway activation due to factor D deficiency by 2 novel mutations in the complement factor D gene in a family with meningococcal infections. Blood. volum 107.
  Academic article
• Mollnes, Tom Eirik; Kirschfink, M. (2006) Complement analysis in clinic and research. Advances in Experimental Medicine and Biology. volum 586.
  Academic article
• Nielsen, Erik Waage; Waage, Christian; Fure, Hilde; Brekke, Ole Lars; Sfyroera, Georgia; Lambris, JD; Mollnes, Tom Eirik. (2006) Effect of supraphysiological levels of C1-inhibitor on the classical, lectin and alternative pathways of complement. ABSTRACT. Regional forskningskonferanse innen medisin og helse.
  Summary/Abstract
• Salvesen, Bodil; Castellheim, Albert; Fung, M.; Saugstad, Ola Didrik; Mollnes, Tom Eirik. (2006) Inflammatory aspects of meconium aspiration syndrome. Biology of the Neonate. volum 89.
  Summary/Abstract
• Salvesen, Bodil; Castellheim, Albert; Pharo, Anne Margrethe; Saugstad, Ola Didrik; Mollnes, Tom Eirik. (2006) Futhan: an efficient inhibitor of meconium-induced complement activation in pig. Molecular Immunology. volum 43 (1-2).
  Summary/Abstract
• Salvesen, Bodil; Saugstad, Ola Didrik; Fung, Michael; Mollnes, Tom Eirik. (2006) Inflammatory Aspects of Meconium Aspiration Syndrome. Biology of the Neonate. volum 89 (206).
  Summary/Abstract
• Sæthre, Marit; Lea, Tor; Borgen, Merethe S.; Fiane, Arnt E.; Michaelsen, Terje Einar;