Torunn Bruland
Torunn Bruland
Top-level researcher, Co Leader CAG-IBD, Unit leader for Gastroenterology, inflammation, and clinic-based research
torunn.bruland@ntnu.no
About
Publications
2026
-
Walaas, Gunnar Andreas Enerhaug;
Sridhar, Arun;
Kuraas, Lusie Frostvoll;
Sæterstad, Siri;
Schioldborg, Amanda Yin;
Granlund, Atle van Beelen;
Sandvik, Arne Kristian;
Østvik, Ann Elisabeth;
Bakke, Ingunn;
Bruland, Torunn.
(2026)
Patient-matched transcriptomics of in vivo and in vitro colonic epithelium substantiate organoids as a translational model for ulcerative colitis.
Scientific Reports
Academic article
2025
-
Rodríguez, Rocío Rivera;
Sæterstad, Siri;
Ali, Ann-Therese Chattergoon;
Selvik, Linn-Karina M.;
Bakke, Ingunn;
Bruland, Torunn;
Johnson, Jeremy J..
(2025)
The dietary phytochemicals carnosic acid and sulforaphane regulate inflammatory markers in ulcerative colitis patient-derived colonoids.
Frontiers in Pharmacology
Academic article
-
Hoz-Martín, María P. de la;
González-Fernández, Juan;
Andreu-Ballester, Juan Carlos;
Høivik, Marte Lie;
Ricanek, Petr;
Bruland, Torunn;
Sandvik, Arne Kristian;
Cuéllar, Carmen;
Catalan Serra, Ignacio.
(2025)
Prevalence of Anti-Anisakis simplex Antibodies in a Cohort of Patients with Inflammatory Bowel Disease in Norway.
Pathogens
Academic article
-
Sridhar, Arun;
Bakke, Ingunn;
Gopalakrishnan, Shreya;
Osoble, Nimo Mukhtar Mohamud;
Hammarqvist, Emilie Prytz;
Pettersen, Henrik Sahlin;
Sandvik, Arne Kristian;
Østvik, Ann Elisabeth;
Hansen, Marianne Dore;
Bruland, Torunn.
(2025)
Tofacitinib and budesonide treatment affect stemness and chemokine release in IBD patient-derived colonoids.
Scientific Reports
Academic article
2024
-
Sæterstad, Siri;
Østvik, Ann Elisabeth;
Hansen, Marianne Dore;
Bruland, Torunn;
Granlund, Atle van Beelen.
(2024)
The effect of rs2910686 on ERAP2 expression in IBD and epithelial inflammatory response.
Journal of Translational Medicine
Academic article
-
Sæterstad, Siri;
Østvik, Ann Elisabeth;
Hansen, Marianne Dore;
Bruland, Torunn;
Granlund, Atle van Beelen.
(2024)
Correction to: The effect of rs2910686 on ERAP2 expression in IBD and epithelial inflammatory response(Journal of Translational Medicine, (2024), 22, 1, (750), 10.1186/s12967-024-05532-w).
Journal of Translational Medicine
Corrigendum
2023
-
Walaas, Gunnar Andreas;
Gopalakrishnan, Shreya;
Bakke, Ingunn;
Skovdahl, Helene Kolstad;
Flatberg, Arnar;
Østvik, Ann Elisabeth;
Sandvik, Arne Kristian;
Bruland, Torunn.
(2023)
Physiological hypoxia improves growth and functional differentiation of human intestinal epithelial organoids.
Frontiers in Immunology
Academic article
-
Catalan-Serra, Ignacio;
Thorsvik, Silje;
Beisvag, Vidar;
Bruland, Torunn;
Underhill, David;
Sandvik, Arne Kristian;
Granlund, Atle van Beelen.
(2023)
Fungal Microbiota Composition in Inflammatory Bowel Disease Patients: Characterization in Different Phenotypes and Correlation With Clinical Activity and Disease Course.
Inflammatory Bowel Diseases
Academic article
-
Gopalakrishnan, Shreya;
Bakke, Ingunn;
Hansen, Marianne Dore;
Skovdahl, Helene Kolstad;
Granlund, Atle van Beelen;
Sandvik, Arne Kristian;
Bruland, Torunn.
(2023)
Comprehensive protocols for culturing and molecular biological analysis of IBD patient-derived colon epithelial organoids.
Frontiers in Immunology
Academic article
2022
-
Gopalakrishnan, Shreya;
Hansen, Marianne Dore;
Skovdahl, Helene Kolstad;
Roseth, Ingrid Aass;
Granlund, Atle van Beelen;
Østvik, Ann Elisabet;
Bakke, Ingunn;
Sandvik, Arne Kristian;
Bruland, Torunn.
(2022)
Tofacitinib Downregulates TNF and Poly(I:C)-Dependent MHC-II Expression in the Colonic Epithelium.
Frontiers in Immunology
Academic article
2021
-
Escudero-Hernandez, Celia;
Granlund, Atle van Beelen;
Bruland, Torunn;
Sandvik, Arne Kristian;
Koch, Stefan;
Østvik, Ann Elisabet;
Münch, Andreas.
(2021)
Transcriptomic Profiling of Collagenous Colitis Identifies Hallmarks of Nondestructive Inflammatory Bowel Disease.
Cellular and Molecular Gastroenterology and Hepatology (CMGH)
Academic article
-
Bakke, Ingunn;
Walaas, Gunnar Andreas;
Bruland, Torunn;
Røyset, Elin Synnøve;
Granlund, Atle van Beelen;
Escudero-Hernandez, Celia;
Thorsvik, Silje;
Münch, Andreas;
Sandvik, Arne Kristian;
Østvik, Ann Elisabet.
(2021)
Mucosal and faecal neutrophil gelatinase-associated lipocalin as potential biomarkers for collagenous colitis.
Journal of gastroenterology
Academic article
-
Bruland, Torunn;
Østvik, Ann Elisabet;
Sandvik, Arne Kristian;
Hansen, Marianne Dore.
(2021)
Host-Viral Interactions in the Pathogenesis of Ulcerative Colitis.
International Journal of Molecular Sciences
Academic literature review
-
Skovdahl, Helene Kolstad;
Gopalakrishnan, Shreya;
Svendsen, Tarjei Dahl;
Granlund, Atle van Beelen;
Bakke, Ingunn;
Ginbot, Zekarias;
Thorsvik, Silje;
Flatberg, Arnar;
Sporsheim, Bjørnar;
Ostrop, Jenny.
(2021)
Patient derived colonoids as drug testing platforms-Critical importance of oxygen concentration.
Frontiers in Pharmacology
Academic article
2020
-
Escudero-Hernandez, Celia;
Granlund, Atle van Beelen;
Bruland, Torunn;
Sandvik, Arne Kristian;
Koch, Stefan;
Østvik, Ann Elisabet;
Münch, Andreas.
(2020)
Whole-genome RNA sequencing in collagenous colitis: a subgroup analysis.
Journal of Crohn`s and Colitis
Conference abstract
-
Bakke, Ingunn;
Bruland, Torunn;
Eriksen, Kaja Sørgård;
Skovdahl, Helene Kolstad;
Gopalakrishnan, Shreya;
Thorsvik, Silje;
Granlund, Atle van Beelen;
Sandvik, Arne Kristian;
Østvik, Ann Elisabet.
(2020)
Differences in expression of PPARγ in small intestine vs. colon impact the effect of 5-aminosalicylates in inflammatory bowel disease.
Journal of Crohn`s and Colitis
Conference abstract
-
Walaas, Gunnar Andreas;
Bakke, Ingunn;
Granlund, Atle van Beelen;
Escudero-Hernandez, Celia;
Bruland, Torunn;
Røyset, Elin Synnøve;
Thorsvik, Silje;
Münch, Andreas;
Østvik, Ann Elisabet;
Sandvik, Arne Kristian.
(2020)
Neutrophil gelatinase-associated lipocalin (NGAL) as biomarker in collagenous colitis.
Journal of Crohn`s and Colitis
Conference abstract
-
Østvik, Ann Elisabet;
Svendsen, Tarjei Dahl;
Granlund, Atle van Beelen;
Doseth, Berit;
Skovdahl, Helene Kolstad;
Bakke, Ingunn;
Thorsvik, Silje;
Afroz, Wahida;
Walaas, Gunnar Andreas;
Mollnes, Tom Eirik.
(2020)
Intestinal epithelial cells express immunomodulatory ISG15 during active ulcerative colitis and Crohn's disease.
Journal of Crohn's and Colitis
Academic article
2019
-
Thorsvik, Silje;
Granlund, Atle van Beelen;
Svendsen, Tarjei Dahl;
Bakke, Ingunn;
Røyset, Elin Synnøve;
Flo, Trude Helen;
Damås, Jan Kristian;
Østvik, Ann Elisabet;
Bruland, Torunn;
Sandvik, Arne Kristian.
(2019)
Ulcer-associated cell lineage expresses genes involved in regeneration and is hallmarked by high neutrophil gelatinase-associated lipocalin (NGAL) levels.
Journal of Pathology
Academic article
2018
-
Østvik, Ann Elisabet;
Svendsen, Tarjei Dahl;
Granlund, Atle van Beelen;
Doseth, Berit;
Bakke, Ingunn;
Thorsvik, Silje;
Afroz, Wahida;
Skovdahl, Helene Kolstad;
Mollnes, Tom Eirik;
Gustafsson, Björn.
(2018)
Tu1753 - type 1 Interferon Signaling in Intestinal Epithelial Cells During Active Inflammatory Bowel Disease.
Gastroenterology
Conference abstract
-
Catalan-Serra, Ignacio;
Andreu-Ballester, Juan Carlos;
Bruland, Torunn;
Sandvik, Arne Kristian.
(2018)
Gammadelta T Cells: Unconventional T Cells Involved in IBD Pathogenesis.
Digestive Diseases and Sciences
Commentary
-
Vange, Pål;
Bruland, Torunn;
Munkvold, Bjørn;
Røyset, Elin Synnøve;
Gleave, Martin E.;
Bakke, Ingunn.
(2018)
Subtle protective roles of clusterin in gastric metaplasia after acute oxyntic atrophy.
Cellular and Molecular Gastroenterology and Hepatology (CMGH)
Academic article
-
Cobo, Isidoro;
Martinelli, Paola;
Flández, Marta;
Bakiri, Latifa;
Zhang, Mingfeng;
Carrillo-de-Santa-Pau, Enrique;
Jia, Jinping;
Lobo, Víctor J. Sánchez-Arévalo;
Megías, Diego;
Felipe, Irene.
(2018)
Transcriptional regulation by NR5A2 links differentiation and inflammation in the pancreas.
Nature
Academic article
-
Skovdahl, Helene Kolstad;
Damås, Jan Kristian;
Granlund, Atle van Beelen;
Østvik, Ann Elisabet;
Doseth, Berit;
Bruland, Torunn;
Mollnes, Tom Eirik;
Sandvik, Arne Kristian.
(2018)
C-C Motif Ligand 20 (CCL20) and C-C Motif Chemokine Receptor 6 (CCR6) in Human Peripheral Blood Mononuclear Cells: Dysregulated in Ulcerative Colitis and a Potential Role for CCL20 in IL-1β Release.
International Journal of Molecular Sciences
Academic article
2017
-
Vange, Pål;
Bruland, Torunn;
Doseth, Berit;
Fossmark, Reidar;
Sousa, Mirta;
Beisvag, Vidar;
Sørdal, Øystein Finset;
Qvigstad, Gunnar;
Waldum, Helge;
Sandvik, Arne Kristian.
(2017)
The cytoprotective protein clusterin is overexpressed in hypergastrinemic rodent models of oxyntic preneoplasia and promotes gastric cancer cell survival.
PLOS ONE
Academic article
-
catalan-Serra, Ignacio;
Sandvik, Arne Kristian;
Bruland, Torunn;
Andreu-Ballester, Juan Carlos.
(2017)
Gammadelta T cells in Crohn's disease: a new player in the disease pathogenesis?.
Journal - Crohn's and Colitis Foundation of Canada
Academic literature review
2016
-
Vange, Pål;
Bruland, Torunn;
Bakke, Ingunn.
(2016)
Author reply to Letter to the Editor entitled: "Controversial role of the possible oxyntic stem cell marker ASPM in gastric cancer".
Journal of Pathology
Commentary
2015
-
Skovdahl, Helene Kolstad;
Granlund, Atle Van Beelen;
Østvik, Ann Elisabet;
Bruland, Torunn;
Bakke, Ingunn;
Torp, Sverre Helge;
Damås, Jan Kristian;
Sandvik, Arne Kristian.
(2015)
Expression of CCL20 and its corresponding receptor CCR6 is enhanced in active inflammatory bowel disease, and TLR3 mediates CCL20 expression in colonic epithelial cells.
PLOS ONE
Academic article
-
Brenna, Øystein;
Bruland, Torunn;
Furnes, Marianne Waldum;
Granlund, Atle Van Beelen;
Drozdov, Ignat;
Emgård, Johanna;
Brønstad, Gunnar;
Kidd, Mark;
Sandvik, Arne Kristian;
Gustafsson, Björn.
(2015)
The guanylate cyclase-C signaling pathway is down-regulated in inflammatory bowel disease.
Scandinavian Journal of Gastroenterology
Academic article
-
Vange, Pål;
Bruland, Torunn;
Beisvag, Vidar;
Erlandsen, Sten Even;
Flatberg, Arnar;
Doseth, Berit;
Sandvik, Arne Kristian;
Bakke, Ingunn.
(2015)
Genome-wide analysis of the oxyntic proliferative isthmus zone reveals ASPM as a possible gastric stem/progenitor cell marker overexpressed in cancer.
Journal of Pathology
Academic article
-
Tripathi, Sushil;
Flobak, Åsmund;
Chawla, Konika;
Baudot, Anaïs;
Bruland, Torunn;
Thommesen, Liv;
Kuiper, Martin Tremen R.;
Lægreid, Astrid.
(2015)
The gastrin and cholecystokinin receptors mediated signaling network: a scaffold for data analysis and new hypotheses on regulatory mechanisms.
BMC Systems Biology
Academic article
2014
-
Selvik, Linn-Karina M.;
Rao, Shalini;
Steigedal, Tonje;
Haltbakk, Ildri;
Misund, Kristine;
Bruland, Torunn;
Prestvik, Wenche S;
Lægreid, Astrid;
Thommesen, Liv.
(2014)
Salt-inducible kinase 1 (SIK1) is induced by gastrin and inhibits migration of gastric adenocarcinoma cells.
PLOS ONE
Academic article
2013
-
Selvik, Linn-Karina M.;
Fjeldbo, Christina Sæten;
Flatberg, Arnar;
Steigedal, Tonje;
Misund, Kristine;
Anderssen, Endre;
Doseth, Berit;
Langaas, Mette;
Tripathi, Sushil;
Beisvag, Vidar.
(2013)
The duration of gastrin treatment affects global gene expression and molecular responses involved in ER stress and anti-apoptosis.
BMC Genomics
Academic article
-
Misund, Kristine;
Selvik, Linn-Karina M.;
Rao, Shalini;
Nørsett, Kristin Gabestad;
Bakke, Ingunn;
Sandvik, Arne;
Lægreid, Astrid;
Bruland, Torunn;
Prestvik, Wenche S;
Thommesen, Liv.
(2013)
NR4A2 is regulated by Gastrin and involved in gastrin-induced migration and invasion of gastric adenocarcinoma cells.
PLOS ONE
Academic article
-
Steigedal, Tonje;
Prestvik, Wenche S;
Selvik, Linn-Karina M.;
Fjeldbo, Christina Sæten;
Bruland, Torunn;
Lægreid, Astrid;
Thommesen, Liv.
(2013)
Gastrin-induced proliferation involves MEK partner 1 (MP1).
In vitro Cellular & Developmental Biology-Animal
Academic article
2012
-
Fjeldbo, Christina Sæten;
Bakke, Ingunn;
Erlandsen, Sten Even;
Holmseth, Jannicke;
Lægreid, Astrid;
Sandvik, Arne Kristian;
Thommesen, Liv;
Bruland, Torunn.
(2012)
Gastrin upregulates the pro-survival factor secretory clusterin (sCLU) in adenocarcinoma cells and in oxyntic mucosa of hypergastrinemic rats.
American Journal of Physiology - Gastrointestinal and Liver Physiology
Academic article
2010
-
Fjeldbo, Christina Sæten;
Misund, Kristine;
Günther, Clara-Cecilie;
Langaas, Mette;
Steigedal, Tonje;
Thommesen, Liv;
Lægreid, Astrid;
Bruland, Torunn.
(2010)
Functional studies on RNA-transfected cell microarrays.
Methods in molecular biology
Academic article
2009
-
Fjeldbo, Christina Sæten;
Bruland, Torunn.
(2009)
Efficient Reverse Transfection of Both siRNA and Expression Plasmids on Transfected Cell Microarrays Using X-tremeGENE siRNA Transfection Reagent.
Biochemica
Academic literature review
2008
-
Fjeldbo, Christina Sæten;
Misund, Kristine;
Gunther, Clara-Cecilie;
Langaas, Mette;
Steigedal, Tonje;
Thommesen, Liv;
Lægreid, Astrid;
Bruland, Torunn.
(2008)
Functional studies on transfected cell microarray analysed by linear regression modelling.
Nucleic Acids Research (NAR)
Academic article
-
Fjeldbo, Christina Sæten;
Misund, Kristine;
Günther, Clara-Cecilie;
Langaas, Mette;
Steigedal, Tonje Strømmen;
Thommesen, Liv;
Lægreid, Astrid;
Bruland, Torunn.
(2008)
Functional studies on transfected cell microarray analysed by linear regression modelling.
Nucleic Acids Research (NAR)
Academic article
2007
-
Steigedal, Tonje;
Bruland, Torunn;
Misund, Kristine;
Thommesen, Liv;
Lægreid, Astrid.
(2007)
Inducible cAMP early repressor suppresses gastrin-mediated activation of cyclin D1 and c-fos gene expression.
American Journal of Physiology - Gastrointestinal and Liver Physiology
Academic article
-
Steigedal, Tonje Strømmen;
Bruland, Torunn;
Misund, Kristine;
Thommesen, Liv;
Lægreid, Astrid.
(2007)
Inducible cAMP early repressor suppresses gastrin-mediated activation of cyclin D1 and c-fos gene expression.
American Journal of Physiology - Gastrointestinal and Liver Physiology
Academic article
-
Bruland, Torunn;
Anderssen, Endre;
Eitrem, Berit Doseth;
Bergum, Hallgeir;
Beisvåg, Vidar;
Lægreid, Astrid.
(2007)
Optimization of cDNA microarrays procedures using criteria that do not rely on external standards.
BMC Genomics
Academic article
2005
-
Thommesen, Liv;
Sæten, Christina;
Steigedal, Tonje Strømmen;
Bruland, Torunn.
(2005)
Bruk av siRNA og RNAi i cellearray i studier av molekylære mekanismer i mage-tarmsystemet.
NBS-nytt
Professional article
-
Thommesen, Liv;
Sæten, Christina;
Strømmen, Tonje;
Bruland, Torunn.
(2005)
Bruk av siRNA og RNAi cellearray i studier av molekylære mekanismer i mage-tarmsystemet.
NBS-nytt
Popular science article
-
Sæten, Christina;
Bruland, Torunn;
Strømmen, Tonje;
Lægreid, Astrid.
(2005)
Optimalisering av Transfekterte CellArray (TCA) for bruk i storskala hypothesetesting av genfunksjon.
IKM, NTNU
Master thesis
2003
-
Lavik, Liss Anne;
Dalen, Are;
Dai, Hong Yan;
Bruland, Torunn.
(2003)
Identification of Friend murine retrovirus infected immune cells and studies of the effects of sex and steroid hormones in the early phase of infection.
APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum
Academic article
-
Bruland, Torunn;
Lavik, Liss Anne;
Dai, Hong Yan;
Dalen, Are.
(2003)
A Glucocorticoid response element in the murine retrovirus FIS-2 LTF enhances virus transcription and is a major determinant for sex-related differences in susceptibility to FIS-2 infection.
Journal of General Virology
Academic article
-
Bruland, Torunn.
(2003)
Studies of early retrovirus-host interactions. Viral determinants for pathogenesis and the influence of sex on the susceptibility to Friend murine leukaemia virus infection.
[Mangler utgivernavn]
Academic monograph
-
Bruland, Torunn;
Lavik, Liss Anne;
Dai, Hong Yan;
Dalen, Are.
(2003)
Identification of Friend murine retrovirus infected immune cells and studies of the effects of sex and steroid hormones in the early phase of infection.
APMIS - Journal of Pathologiy, Microbiology and Immunology
Academic article
2001
-
Bruland, Torunn;
Dai, Hong Yan;
Lavik, Liss Anne;
Kristiansen, Lena I.;
Dalen, Are.
(2001)
Genderrelated difference in susceptibility, early virus dissemination and immunosuppression in mice infected with Friend murine leukaemia virus variant FIS-2.
Journal of General Virology
Academic article
1998
-
Dai, Hong Yan;
Troseth, Gunn Irene;
Gunleksrud, Merete;
Bruland, Torunn;
Solberg, Liss Anne;
Aarset, Harald;
Kristiansen, Lena Irene;
Dalen, Are.
(1998)
Identification of genetic determinants responsible for the rapid immunosuppressive activity and the low leukemogenic potential of a variant of Friend leukemia virus, FIS-2.
Journal of Virology
Academic article
Journal publications
-
Walaas, Gunnar Andreas Enerhaug;
Sridhar, Arun;
Kuraas, Lusie Frostvoll;
Sæterstad, Siri;
Schioldborg, Amanda Yin;
Granlund, Atle van Beelen;
Sandvik, Arne Kristian;
Østvik, Ann Elisabeth;
Bakke, Ingunn;
Bruland, Torunn.
(2026)
Patient-matched transcriptomics of in vivo and in vitro colonic epithelium substantiate organoids as a translational model for ulcerative colitis.
Scientific Reports
Academic article
-
Rodríguez, Rocío Rivera;
Sæterstad, Siri;
Ali, Ann-Therese Chattergoon;
Selvik, Linn-Karina M.;
Bakke, Ingunn;
Bruland, Torunn;
Johnson, Jeremy J..
(2025)
The dietary phytochemicals carnosic acid and sulforaphane regulate inflammatory markers in ulcerative colitis patient-derived colonoids.
Frontiers in Pharmacology
Academic article
-
Vange, Pål;
Bruland, Torunn;
Bakke, Ingunn.
(2016)
Author reply to Letter to the Editor entitled: "Controversial role of the possible oxyntic stem cell marker ASPM in gastric cancer".
Journal of Pathology
Commentary
-
Escudero-Hernandez, Celia;
Granlund, Atle van Beelen;
Bruland, Torunn;
Sandvik, Arne Kristian;
Koch, Stefan;
Østvik, Ann Elisabet;
Münch, Andreas.
(2021)
Transcriptomic Profiling of Collagenous Colitis Identifies Hallmarks of Nondestructive Inflammatory Bowel Disease.
Cellular and Molecular Gastroenterology and Hepatology (CMGH)
Academic article
-
Vange, Pål;
Bruland, Torunn;
Doseth, Berit;
Fossmark, Reidar;
Sousa, Mirta;
Beisvag, Vidar;
Sørdal, Øystein Finset;
Qvigstad, Gunnar;
Waldum, Helge;
Sandvik, Arne Kristian.
(2017)
The cytoprotective protein clusterin is overexpressed in hypergastrinemic rodent models of oxyntic preneoplasia and promotes gastric cancer cell survival.
PLOS ONE
Academic article
-
catalan-Serra, Ignacio;
Sandvik, Arne Kristian;
Bruland, Torunn;
Andreu-Ballester, Juan Carlos.
(2017)
Gammadelta T cells in Crohn's disease: a new player in the disease pathogenesis?.
Journal - Crohn's and Colitis Foundation of Canada
Academic literature review
-
Fjeldbo, Christina Sæten;
Misund, Kristine;
Gunther, Clara-Cecilie;
Langaas, Mette;
Steigedal, Tonje;
Thommesen, Liv;
Lægreid, Astrid;
Bruland, Torunn.
(2008)
Functional studies on transfected cell microarray analysed by linear regression modelling.
Nucleic Acids Research (NAR)
Academic article
-
Lavik, Liss Anne;
Dalen, Are;
Dai, Hong Yan;
Bruland, Torunn.
(2003)
Identification of Friend murine retrovirus infected immune cells and studies of the effects of sex and steroid hormones in the early phase of infection.
APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum
Academic article
-
Thommesen, Liv;
Sæten, Christina;
Steigedal, Tonje Strømmen;
Bruland, Torunn.
(2005)
Bruk av siRNA og RNAi i cellearray i studier av molekylære mekanismer i mage-tarmsystemet.
NBS-nytt
Professional article
-
Østvik, Ann Elisabet;
Svendsen, Tarjei Dahl;
Granlund, Atle van Beelen;
Doseth, Berit;
Bakke, Ingunn;
Thorsvik, Silje;
Afroz, Wahida;
Skovdahl, Helene Kolstad;
Mollnes, Tom Eirik;
Gustafsson, Björn.
(2018)
Tu1753 - type 1 Interferon Signaling in Intestinal Epithelial Cells During Active Inflammatory Bowel Disease.
Gastroenterology
Conference abstract
-
Walaas, Gunnar Andreas;
Gopalakrishnan, Shreya;
Bakke, Ingunn;
Skovdahl, Helene Kolstad;
Flatberg, Arnar;
Østvik, Ann Elisabeth;
Sandvik, Arne Kristian;
Bruland, Torunn.
(2023)
Physiological hypoxia improves growth and functional differentiation of human intestinal epithelial organoids.
Frontiers in Immunology
Academic article
-
Sæterstad, Siri;
Østvik, Ann Elisabeth;
Hansen, Marianne Dore;
Bruland, Torunn;
Granlund, Atle van Beelen.
(2024)
The effect of rs2910686 on ERAP2 expression in IBD and epithelial inflammatory response.
Journal of Translational Medicine
Academic article
-
Thommesen, Liv;
Sæten, Christina;
Strømmen, Tonje;
Bruland, Torunn.
(2005)
Bruk av siRNA og RNAi cellearray i studier av molekylære mekanismer i mage-tarmsystemet.
NBS-nytt
Popular science article
-
Catalan-Serra, Ignacio;
Thorsvik, Silje;
Beisvag, Vidar;
Bruland, Torunn;
Underhill, David;
Sandvik, Arne Kristian;
Granlund, Atle van Beelen.
(2023)
Fungal Microbiota Composition in Inflammatory Bowel Disease Patients: Characterization in Different Phenotypes and Correlation With Clinical Activity and Disease Course.
Inflammatory Bowel Diseases
Academic article
-
Bakke, Ingunn;
Walaas, Gunnar Andreas;
Bruland, Torunn;
Røyset, Elin Synnøve;
Granlund, Atle van Beelen;
Escudero-Hernandez, Celia;
Thorsvik, Silje;
Münch, Andreas;
Sandvik, Arne Kristian;
Østvik, Ann Elisabet.
(2021)
Mucosal and faecal neutrophil gelatinase-associated lipocalin as potential biomarkers for collagenous colitis.
Journal of gastroenterology
Academic article
-
Escudero-Hernandez, Celia;
Granlund, Atle van Beelen;
Bruland, Torunn;
Sandvik, Arne Kristian;
Koch, Stefan;
Østvik, Ann Elisabet;
Münch, Andreas.
(2020)
Whole-genome RNA sequencing in collagenous colitis: a subgroup analysis.
Journal of Crohn`s and Colitis
Conference abstract
-
Catalan-Serra, Ignacio;
Andreu-Ballester, Juan Carlos;
Bruland, Torunn;
Sandvik, Arne Kristian.
(2018)
Gammadelta T Cells: Unconventional T Cells Involved in IBD Pathogenesis.
Digestive Diseases and Sciences
Commentary
-
Bakke, Ingunn;
Bruland, Torunn;
Eriksen, Kaja Sørgård;
Skovdahl, Helene Kolstad;
Gopalakrishnan, Shreya;
Thorsvik, Silje;
Granlund, Atle van Beelen;
Sandvik, Arne Kristian;
Østvik, Ann Elisabet.
(2020)
Differences in expression of PPARγ in small intestine vs. colon impact the effect of 5-aminosalicylates in inflammatory bowel disease.
Journal of Crohn`s and Colitis
Conference abstract
-
Walaas, Gunnar Andreas;
Bakke, Ingunn;
Granlund, Atle van Beelen;
Escudero-Hernandez, Celia;
Bruland, Torunn;
Røyset, Elin Synnøve;
Thorsvik, Silje;
Münch, Andreas;
Østvik, Ann Elisabet;
Sandvik, Arne Kristian.
(2020)
Neutrophil gelatinase-associated lipocalin (NGAL) as biomarker in collagenous colitis.
Journal of Crohn`s and Colitis
Conference abstract
-
Hoz-Martín, María P. de la;
González-Fernández, Juan;
Andreu-Ballester, Juan Carlos;
Høivik, Marte Lie;
Ricanek, Petr;
Bruland, Torunn;
Sandvik, Arne Kristian;
Cuéllar, Carmen;
Catalan Serra, Ignacio.
(2025)
Prevalence of Anti-Anisakis simplex Antibodies in a Cohort of Patients with Inflammatory Bowel Disease in Norway.
Pathogens
Academic article
-
Dai, Hong Yan;
Troseth, Gunn Irene;
Gunleksrud, Merete;
Bruland, Torunn;
Solberg, Liss Anne;
Aarset, Harald;
Kristiansen, Lena Irene;
Dalen, Are.
(1998)
Identification of genetic determinants responsible for the rapid immunosuppressive activity and the low leukemogenic potential of a variant of Friend leukemia virus, FIS-2.
Journal of Virology
Academic article
-
Vange, Pål;
Bruland, Torunn;
Munkvold, Bjørn;
Røyset, Elin Synnøve;
Gleave, Martin E.;
Bakke, Ingunn.
(2018)
Subtle protective roles of clusterin in gastric metaplasia after acute oxyntic atrophy.
Cellular and Molecular Gastroenterology and Hepatology (CMGH)
Academic article
-
Fjeldbo, Christina Sæten;
Misund, Kristine;
Günther, Clara-Cecilie;
Langaas, Mette;
Steigedal, Tonje Strømmen;
Thommesen, Liv;
Lægreid, Astrid;
Bruland, Torunn.
(2008)
Functional studies on transfected cell microarray analysed by linear regression modelling.
Nucleic Acids Research (NAR)
Academic article
-
Selvik, Linn-Karina M.;
Fjeldbo, Christina Sæten;
Flatberg, Arnar;
Steigedal, Tonje;
Misund, Kristine;
Anderssen, Endre;
Doseth, Berit;
Langaas, Mette;
Tripathi, Sushil;
Beisvag, Vidar.
(2013)
The duration of gastrin treatment affects global gene expression and molecular responses involved in ER stress and anti-apoptosis.
BMC Genomics
Academic article
-
Selvik, Linn-Karina M.;
Rao, Shalini;
Steigedal, Tonje;
Haltbakk, Ildri;
Misund, Kristine;
Bruland, Torunn;
Prestvik, Wenche S;
Lægreid, Astrid;
Thommesen, Liv.
(2014)
Salt-inducible kinase 1 (SIK1) is induced by gastrin and inhibits migration of gastric adenocarcinoma cells.
PLOS ONE
Academic article
-
Steigedal, Tonje;
Bruland, Torunn;
Misund, Kristine;
Thommesen, Liv;
Lægreid, Astrid.
(2007)
Inducible cAMP early repressor suppresses gastrin-mediated activation of cyclin D1 and c-fos gene expression.
American Journal of Physiology - Gastrointestinal and Liver Physiology
Academic article
-
Gopalakrishnan, Shreya;
Bakke, Ingunn;
Hansen, Marianne Dore;
Skovdahl, Helene Kolstad;
Granlund, Atle van Beelen;
Sandvik, Arne Kristian;
Bruland, Torunn.
(2023)
Comprehensive protocols for culturing and molecular biological analysis of IBD patient-derived colon epithelial organoids.
Frontiers in Immunology
Academic article
-
Cobo, Isidoro;
Martinelli, Paola;
Flández, Marta;
Bakiri, Latifa;
Zhang, Mingfeng;
Carrillo-de-Santa-Pau, Enrique;
Jia, Jinping;
Lobo, Víctor J. Sánchez-Arévalo;
Megías, Diego;
Felipe, Irene.
(2018)
Transcriptional regulation by NR5A2 links differentiation and inflammation in the pancreas.
Nature
Academic article
-
Misund, Kristine;
Selvik, Linn-Karina M.;
Rao, Shalini;
Nørsett, Kristin Gabestad;
Bakke, Ingunn;
Sandvik, Arne;
Lægreid, Astrid;
Bruland, Torunn;
Prestvik, Wenche S;
Thommesen, Liv.
(2013)
NR4A2 is regulated by Gastrin and involved in gastrin-induced migration and invasion of gastric adenocarcinoma cells.
PLOS ONE
Academic article
-
Skovdahl, Helene Kolstad;
Granlund, Atle Van Beelen;
Østvik, Ann Elisabet;
Bruland, Torunn;
Bakke, Ingunn;
Torp, Sverre Helge;
Damås, Jan Kristian;
Sandvik, Arne Kristian.
(2015)
Expression of CCL20 and its corresponding receptor CCR6 is enhanced in active inflammatory bowel disease, and TLR3 mediates CCL20 expression in colonic epithelial cells.
PLOS ONE
Academic article
-
Gopalakrishnan, Shreya;
Hansen, Marianne Dore;
Skovdahl, Helene Kolstad;
Roseth, Ingrid Aass;
Granlund, Atle van Beelen;
Østvik, Ann Elisabet;
Bakke, Ingunn;
Sandvik, Arne Kristian;
Bruland, Torunn.
(2022)
Tofacitinib Downregulates TNF and Poly(I:C)-Dependent MHC-II Expression in the Colonic Epithelium.
Frontiers in Immunology
Academic article
-
Sæterstad, Siri;
Østvik, Ann Elisabeth;
Hansen, Marianne Dore;
Bruland, Torunn;
Granlund, Atle van Beelen.
(2024)
Correction to: The effect of rs2910686 on ERAP2 expression in IBD and epithelial inflammatory response(Journal of Translational Medicine, (2024), 22, 1, (750), 10.1186/s12967-024-05532-w).
Journal of Translational Medicine
Corrigendum
-
Brenna, Øystein;
Bruland, Torunn;
Furnes, Marianne Waldum;
Granlund, Atle Van Beelen;
Drozdov, Ignat;
Emgård, Johanna;
Brønstad, Gunnar;
Kidd, Mark;
Sandvik, Arne Kristian;
Gustafsson, Björn.
(2015)
The guanylate cyclase-C signaling pathway is down-regulated in inflammatory bowel disease.
Scandinavian Journal of Gastroenterology
Academic article
-
Vange, Pål;
Bruland, Torunn;
Beisvag, Vidar;
Erlandsen, Sten Even;
Flatberg, Arnar;
Doseth, Berit;
Sandvik, Arne Kristian;
Bakke, Ingunn.
(2015)
Genome-wide analysis of the oxyntic proliferative isthmus zone reveals ASPM as a possible gastric stem/progenitor cell marker overexpressed in cancer.
Journal of Pathology
Academic article
-
Tripathi, Sushil;
Flobak, Åsmund;
Chawla, Konika;
Baudot, Anaïs;
Bruland, Torunn;
Thommesen, Liv;
Kuiper, Martin Tremen R.;
Lægreid, Astrid.
(2015)
The gastrin and cholecystokinin receptors mediated signaling network: a scaffold for data analysis and new hypotheses on regulatory mechanisms.
BMC Systems Biology
Academic article
-
Fjeldbo, Christina Sæten;
Misund, Kristine;
Günther, Clara-Cecilie;
Langaas, Mette;
Steigedal, Tonje;
Thommesen, Liv;
Lægreid, Astrid;
Bruland, Torunn.
(2010)
Functional studies on RNA-transfected cell microarrays.
Methods in molecular biology
Academic article
-
Skovdahl, Helene Kolstad;
Damås, Jan Kristian;
Granlund, Atle van Beelen;
Østvik, Ann Elisabet;
Doseth, Berit;
Bruland, Torunn;
Mollnes, Tom Eirik;
Sandvik, Arne Kristian.
(2018)
C-C Motif Ligand 20 (CCL20) and C-C Motif Chemokine Receptor 6 (CCR6) in Human Peripheral Blood Mononuclear Cells: Dysregulated in Ulcerative Colitis and a Potential Role for CCL20 in IL-1β Release.
International Journal of Molecular Sciences
Academic article
-
Østvik, Ann Elisabet;
Svendsen, Tarjei Dahl;
Granlund, Atle van Beelen;
Doseth, Berit;
Skovdahl, Helene Kolstad;
Bakke, Ingunn;
Thorsvik, Silje;
Afroz, Wahida;
Walaas, Gunnar Andreas;
Mollnes, Tom Eirik.
(2020)
Intestinal epithelial cells express immunomodulatory ISG15 during active ulcerative colitis and Crohn's disease.
Journal of Crohn's and Colitis
Academic article
-
Steigedal, Tonje Strømmen;
Bruland, Torunn;
Misund, Kristine;
Thommesen, Liv;
Lægreid, Astrid.
(2007)
Inducible cAMP early repressor suppresses gastrin-mediated activation of cyclin D1 and c-fos gene expression.
American Journal of Physiology - Gastrointestinal and Liver Physiology
Academic article
-
Bruland, Torunn;
Lavik, Liss Anne;
Dai, Hong Yan;
Dalen, Are.
(2003)
A Glucocorticoid response element in the murine retrovirus FIS-2 LTF enhances virus transcription and is a major determinant for sex-related differences in susceptibility to FIS-2 infection.
Journal of General Virology
Academic article
-
Thorsvik, Silje;
Granlund, Atle van Beelen;
Svendsen, Tarjei Dahl;
Bakke, Ingunn;
Røyset, Elin Synnøve;
Flo, Trude Helen;
Damås, Jan Kristian;
Østvik, Ann Elisabet;
Bruland, Torunn;
Sandvik, Arne Kristian.
(2019)
Ulcer-associated cell lineage expresses genes involved in regeneration and is hallmarked by high neutrophil gelatinase-associated lipocalin (NGAL) levels.
Journal of Pathology
Academic article
-
Bruland, Torunn;
Lavik, Liss Anne;
Dai, Hong Yan;
Dalen, Are.
(2003)
Identification of Friend murine retrovirus infected immune cells and studies of the effects of sex and steroid hormones in the early phase of infection.
APMIS - Journal of Pathologiy, Microbiology and Immunology
Academic article
-
Fjeldbo, Christina Sæten;
Bakke, Ingunn;
Erlandsen, Sten Even;
Holmseth, Jannicke;
Lægreid, Astrid;
Sandvik, Arne Kristian;
Thommesen, Liv;
Bruland, Torunn.
(2012)
Gastrin upregulates the pro-survival factor secretory clusterin (sCLU) in adenocarcinoma cells and in oxyntic mucosa of hypergastrinemic rats.
American Journal of Physiology - Gastrointestinal and Liver Physiology
Academic article
-
Steigedal, Tonje;
Prestvik, Wenche S;
Selvik, Linn-Karina M.;
Fjeldbo, Christina Sæten;
Bruland, Torunn;
Lægreid, Astrid;
Thommesen, Liv.
(2013)
Gastrin-induced proliferation involves MEK partner 1 (MP1).
In vitro Cellular & Developmental Biology-Animal
Academic article
-
Bruland, Torunn;
Østvik, Ann Elisabet;
Sandvik, Arne Kristian;
Hansen, Marianne Dore.
(2021)
Host-Viral Interactions in the Pathogenesis of Ulcerative Colitis.
International Journal of Molecular Sciences
Academic literature review
-
Fjeldbo, Christina Sæten;
Bruland, Torunn.
(2009)
Efficient Reverse Transfection of Both siRNA and Expression Plasmids on Transfected Cell Microarrays Using X-tremeGENE siRNA Transfection Reagent.
Biochemica
Academic literature review
-
Skovdahl, Helene Kolstad;
Gopalakrishnan, Shreya;
Svendsen, Tarjei Dahl;
Granlund, Atle van Beelen;
Bakke, Ingunn;
Ginbot, Zekarias;
Thorsvik, Silje;
Flatberg, Arnar;
Sporsheim, Bjørnar;
Ostrop, Jenny.
(2021)
Patient derived colonoids as drug testing platforms-Critical importance of oxygen concentration.
Frontiers in Pharmacology
Academic article
-
Sridhar, Arun;
Bakke, Ingunn;
Gopalakrishnan, Shreya;
Osoble, Nimo Mukhtar Mohamud;
Hammarqvist, Emilie Prytz;
Pettersen, Henrik Sahlin;
Sandvik, Arne Kristian;
Østvik, Ann Elisabeth;
Hansen, Marianne Dore;
Bruland, Torunn.
(2025)
Tofacitinib and budesonide treatment affect stemness and chemokine release in IBD patient-derived colonoids.
Scientific Reports
Academic article
-
Bruland, Torunn;
Dai, Hong Yan;
Lavik, Liss Anne;
Kristiansen, Lena I.;
Dalen, Are.
(2001)
Genderrelated difference in susceptibility, early virus dissemination and immunosuppression in mice infected with Friend murine leukaemia virus variant FIS-2.
Journal of General Virology
Academic article
-
Bruland, Torunn;
Anderssen, Endre;
Eitrem, Berit Doseth;
Bergum, Hallgeir;
Beisvåg, Vidar;
Lægreid, Astrid.
(2007)
Optimization of cDNA microarrays procedures using criteria that do not rely on external standards.
BMC Genomics
Academic article
Books
-
Bruland, Torunn.
(2003)
Studies of early retrovirus-host interactions. Viral determinants for pathogenesis and the influence of sex on the susceptibility to Friend murine leukaemia virus infection.
[Mangler utgivernavn]
Academic monograph
Student thesis or dissertation
-
Sæten, Christina;
Bruland, Torunn;
Strømmen, Tonje;
Lægreid, Astrid.
(2005)
Optimalisering av Transfekterte CellArray (TCA) for bruk i storskala hypothesetesting av genfunksjon.
IKM, NTNU
Master thesis
Teaching
Courses
Outreach
2025
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InterviewEgge, Håvard Hagene; Bakke, Ingunn; Bruland, Torunn; Østvik, Ann Elisabeth; Haukaas, Tonje Husby. (2025) Nytt håp for pasienter med kronisk tarmbetennelse.
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Conference lectureWalaas, Gunnar Andreas Enerhaug; Sveaas, Silje; Kuraas, Lusie Frostvoll; Sridhar, Arun; Lillebråten, Kari; Fossen, Hanne; Pettersen, Henrik Sahlin; Flatberg, Arnar; Granlund, Atle van Beelen; Sandvik, Arne Kristian. (2025) Humoral immune signatures in uninflamed colon mucosa associated with anti-TNF treatment failure in ulcerative colitis. UEG Week
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Conference posterWalaas, Gunnar Andreas Enerhaug; Sridhar, Arun; Kuraas, Lusie Frostvoll; Sæterstad, Siri; Schioldborg, Amanda Yin; Granlund, Atle van Beelen; Sandvik, Arne Kristian; Østvik, Ann Elisabeth; Bakke, Ingunn; Bruland, Torunn. (2025) Organoids as translational tools: Patient-matched transcriptomics reveals similarities between in vitro and in vivo epithelial responses in ulcerative colitis. Organoids: modelling organ development and disease in 3D
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Conference posterSridhar, Arun; Walaas, Gunnar Andreas Enerhaug; Sæterstad, Siri; Myrmehl, Johan Pierre Durand; Cermakova, Romana; Myrseth, Marte Gisvold; Grundel, Leona; Hansen, Marianne Dore; Østvik, Ann Elisabeth; Bakke, Ingunn. (2025) Approved and investigational JAK/TYK2 inhibitors attenuate inflammatory pathways and promote mucosal homeostasis in IBD patient-derived organoids. Organoids: modelling organ development and disease in 3D
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Conference posterWalaas, Gunnar Andreas Enerhaug; Kuraas, Lusie Frostvoll; Ali, Ann-Therese Chattergoon; Christensen, Tone; Beisvag, Vidar; Bruland, Torunn; Østvik, Ann Elisabeth; Bakke, Ingunn. (2025) Achieving Spatial Transcriptomic Data from Colonic Mucosal Compartments using FFPE Tissue and Laser Capture Microdissection. NBS Contact Meeting 2025
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Conference lectureSridhar, Arun; Walaas, Gunnar Andreas Enerhaug; Sæterstad, Siri; Hansen, Marianne Dore; Østvik, Ann Elisabeth; Bakke, Ingunn; Bruland, Torunn. (2025) Investigating the effects of JAK-inhibitors on inflammatory responses in intestinal epithelial cells using IBD patient-derived colonoids. 60th NBS Contact Meeting
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Conference posterNakstad, Vu To; Sigfúsdóttir, Margrét Sylvía; Chahal, Aman Singh; Haukaas, Tonje Husby; Ringers, Christa; Bwanika, Henri Colyn Harry; Sæterstad, Siri; Bruland, Torunn; Bakke, Ingunn; Østvik, Ann Elisabeth. (2025) Miniaturization of patient- and stem cell derived organoids – increasing throughput and reproducibility. NBS Contact Meeting
2024
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Conference posterSæterstad, Siri; Østvik, Ann Elisabeth; Hansen, Marianne Dore; Bruland, Torunn; Granlund, Atle van Beelen. (2024) Utilizing patient-derived colon organoids to explore the effect of genetically determined ERAP2-proficiency upon proinflammatory stimulation. IBD NORDIC CONFERENCE
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Conference posterSæterstad, Siri; Østvik, Ann Elisabeth; Hansen, Marianne Dore; Bruland, Torunn; Granlund, Atle van Beelen. (2024) Utilizing patient-derived colon organoids to explore the effect of genetically determined ERAP2-proficiency upon proinflammatory stimulation. UEG Week
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Conference posterSridhar, Arun; Bakke, Ingunn; Østvik, Ann Elisabeth; Pettersen, Henrik Sahlin; Bruland, Torunn. (2024) The impact of tofacitinib and budesonide on stemness, cell death, and chemokine release in IBD patient-derived colonoids. UEG Week
2023
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Conference lectureWalaas, Gunnar Andreas; Gopalakrishnan, Shreya; Bakke, Ingunn; Skovdahl, Helene Kolstad; Flatberg, Arnar; Østvik, Ann Elisabeth; Sandvik, Arne Kristian; Bruland, Torunn. (2023) Fysiologisk hypoksi forbedrer vekst og funksjonell differensiering av humane tarmepitelorganoider. Norsk Gastroenterologisk Forening
2021
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Conference lectureBakke, Ingunn; Walaas, Gunnar Andreas; Bruland, Torunn; Røyset, Elin Synnøve; Granlund, Atle van Beelen; Escudero-hernandez, Celia; Thorsvik, Silje; Münch, Andreas; Sandvik, Arne Kristian; Østvik, Ann Elisabet. (2021) Slimhinne og fekal neutrofil gelatinase-assosiert lipocalin (NGAL) som potensiell biomarkør for kollagenøs kolitt. Norsk gastroenterologisk forenings årsmøte
2020
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Conference lectureWalaas, Gunnar Andreas; Bakke, Ingunn; Granlund, Atle van Beelen; Escudero-Hernandez, Celia; Bruland, Torunn; Røyset, Elin Synnøve; Thorsvik, Silje; Münch, Andreas; Østvik, Ann Elisabet; Sandvik, Arne Kristian. (2020) Neutrophil gelatinase-associated lipocalin (NGAL) as biomarker in collagenous colitis (CC). European Microscopic Colitis Group meeting
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Conference lectureWalaas, Gunnar Andreas; Bakke, Ingunn; Granlund, Atle van Beelen; Escuderos-hernandez, celia; Bruland, Torunn; Røyset, Elin Synnøve; Thorsvik, Silje; Münch, Andreas; Østvik, Ann Elisabet; Sandvik, Arne Kristian. (2020) Neutrophil gelatinase-associate lipocalin (NGAL) as biomarker in collagenous colitis. European Crohn's and Colitis organisation congress
2019
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Conference lectureEscudero-Hernandez, Celia; Granlund, Atle van Beelen; Bruland, Torunn; Sandvik, Arne Kristian; Koch, Stefan; Østvik, Ann Elisabet; Münch, Andreas. (2019) MOLECULAR CLASSIFICATION OF COLLAGENOUS COLITIS BY WHOLE-GENOME SEQUENCING. UEGW;United European Gastroenterology Week
2018
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Conference posterSkovdahl, Helene Kolstad; Bruland, Torunn; Damås, Jan Kristian; Granlund, Atle van Beelen; Østvik, Ann Elisabet; Doseth, Berit; Mollnes, Tom Eirik; Sandvik, Arne Kristian. (2018) P093 CCL20 and CCR6 on peripheral blood mononuclear cells (PBMC) in inflammatory bowel disease (IBD): a more potent chemokine in ulcerative colitis. 13th Congress of ECCO
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Conference posterThorsvik, Silje; Granlund, Atle van Beelen; Svendsen, Tarjei Dahl; Bakke, Ingunn; Røyset, Elin Synnøve; Afroz, Wahida; Doseth, Berit; Flo, Trude Helen; Damås, Jan Kristian; Østvik, Ann Elisabet. (2018) Neutrophil Gelatinase-Associated Lipocalin (NGAL) is expressed in regenerative intestinal epithelium and proinflammatory cytokines induce NGAL in human colonoids. Digestive Disease Week (DDW
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Conference lectureSkovdahl, Helene Kolstad; Damås, Jan Kristian; Granlund, Atle van Beelen; Østvik, Ann Elisabet; Bruland, Torunn; Doseth, Berit; Sandvik, Arne Kristian; Mollnes, Tom Eirik. (2018) CCL20 and CCR6 in peripheral blood mononuclear cells (PBMCs) in Inflammatory Bowel Disease (IBD): A more potent chemokine in Ulcerative Colitis. Y-ECCO Basic Science Workshop
2016
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Conference lectureVange, Pål; Bruland, Torunn; Doseth, Berit; Sousa, Mirta; Sørdal, Øystein Finset; Qvigstad, Gunnar; Fossmark, Reidar; Waldum, Helge; Sandvik, Arne Kristian; Bakke, Ingunn. (2016) The anti-apoptotic factor clusterin is involved in hypergastrinemia-induced remodeling of the gastric oxyntic mucosa. United European Gastroenterology Week 2016
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Conference posterSvendsen, Tarjei Dahl; Furnes, Marianne Waldum; Brenna, Øystein; Zwiggelaar, Rosalie; Ryeng, Einar; Lie, Kai-Inge; Beisvag, Vidar; Granlund, Atle van Beelen; Sandvik, Arne Kristian; Bruland, Torunn. (2016) A longitudinal study of the gut microbiome in the IL-10 -/- mice model of coloenteritis reveals correlations between diet, gene expression and inflammation. European Mucosal Immunology Group meeting
2015
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Conference posterGranlund, Atle van Beelen; Flatberg, Arnar; Østvik, Ann Elisabet; Bakke, Ingunn; Bruland, Torunn; Sandvik, Arne Kristian. (2015) Antigen presentation activity of the Intestinal Epithelial Cells. AIBD 2015
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Conference lectureVange, Pål; Bruland, Torunn; Beisvag, Vidar; Erlandsen, Sten Even; Doseth, Berit; Sandvik, Arne Kristian; Bakke, Ingunn. (2015) Genome-wide analysis of the oxyntic proliferative isthmus zone reveals ASPM as a putative gastric stem/progenitor cell marker overexpressed in cancer. Digestive Disease Week 2015
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Conference posterØstvik, Ann Elisabet; Granlund, Atle van Beelen; Flatberg, Arnar; Damås, Jan Kristian; Bruland, Torunn; Sandvik, Arne Kristian. (2015) Waves of epithelial TLR5 and TLR3 signaling in the pathogenesis of inflammatory bowel disease (IBD). TOLL 2015 Targeting Innate Immunity
2014
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Conference lectureSkovdahl, Helene Kolstad; Granlund, Atle Van Beelen; Østvik, Ann Elisabet; Bruland, Torunn; Torp, Sverre Helge; Flatberg, Arnar; Damås, Jan Kristian; Sandvik, Arne Kristian. (2014) Expression of CCL20 and its corresponding receptor CCR6 is located to epithelium and infiltrating cells in the mucosa of IBD patients. Frampeik
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Conference posterVange, Pål; Beisvag, Vidar; Flatberg, Arnar; Afroz, Wahida; Nordrum, Ivar Skjåk; Sørdal, Øystein Finset; Qvigstad, Gunnar; Thommesen, Liv; Lægreid, Astrid; Sandvik, Arne Kristian. (2014) Molecular mechanisms of cellular stress responses in gastric cancer. Digestive Disease Week 2014
2013
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Conference posterVange, Pål; Beisvag, Vidar; Flatberg, Arnar; Rao, Shalini; Sandvik, Arne Kristian; Thommesen, Liv; Bruland, Torunn; Bakke, Ingunn. (2013) Gastric cancer biology – clusterin facilitates the growth promoting effects of gastrin. NBS Contact Meeting 2013
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Conference posterRao, Shalini; Selvik, Linn-Karina M.; Nørsett, Kristin Gabestad; Bakke, Ingunn; Misund, Kristine; Bruland, Torunn; S, Prestvik Wenche; Lægreid, Astrid; Thommesen, Liv. (2013) NR4A2 is regulated by gastrin and influences cellular responses in gastric adenocarcinoma cells. Nuclear receptors: Linking molecules, genomes & physiology
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Conference lectureVange, Pål; Erlandsen, Sten Even; Flatberg, Arnar; Beisvag, Vidar; Bruland, Torunn; Sandvik, Arne; Bakke, Ingunn. (2013) Gene expression analysis of the proliferative zone in gastric oxyntic mucosa. Legestudentenes forskningskonferanse (Frampeik)
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Conference posterRao, Shalini; Thommesen, Liv; Nørsett, Kristin; Bakke, Ingunn; Misund, Kristine; Bruland, Torunn; Prestvik, Wenche S; Lægreid, Astrid. (2013) Nr4A2 is regulated by gastrin and influences cellular responses in gastric adenocarcinoma cells. Kontaktmøte Norsk Biokjemisk Selskap
2011
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Conference posterTripathi, Sushil; Venkatesan, Aravind; Egaña, Mikel; Zavareh, Zahra; Chawla, Konika; Mironov, Vladimir; Thommesen, Liv; Bruland, Torunn; Kuiper, Martin; Lægreid, Astrid. (2011) Automated Assessment of High Throughput Hypotheses on Gene Regulatory Mechanisms Involved in the Gastrin Response. Bio-Ontologies 2011
2010
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Conference posterBruland, Torunn; Anderssen, Endre; Misund, Kristine; Fjeldbo, Christina Sæten; Flatberg, Arnar; Selvik, Linn-Karina M.; Beisvag, Vidar; Sandvik, Arne Kristian; Lægreid, Astrid; Thommesen, Liv. (2010) Exploring signal-induced cellular regulatory subnetworks by use of partial least square regression (PLSR) multidimensional analysis of gene expression time series data. 13th Annual MGED meeting , Boston, Massachusetts, USA
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Conference lectureBruland, Torunn. (2010) Exploring signal-induced cellular regulatory networks by gene expression analysis. Onsdagsmøte IKM
2009
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Conference lectureSelvik, Linn-Karina M.; Misund, Kristine; Fjeldbo, Christina Sæten; Steigedal, Tonje; Bruland, Torunn; Lægreid, Astrid; Thommesen, Liv. (2009) Salt-inducible kinase 1 (SIK1) is involved in the gastrin-mediated growth response and is repressed by ICER and Zfp36l1. NBS Kontaktmøte 2009
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Conference lectureSelvik, Linn Karina Myrland; Steigedal, Tonje Strømmen; Bruland, Torunn; Thommesen, Liv. (2009) Salt-inducible kinase 1 (SIK1) is involved in the gastrin-mediated growth response and is repressed by ICER and Zfp36Il. Contact Meeting NBS
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Conference posterAnderssen, Endre; Bruland, Torunn; Misund, Kristine; Sandvik, Arne K.; Thommesen, Liv; Lægreid, Astrid. (2009) Using basic networks motifs and biological background knowledge to analyze transcriptomic time series data. MGED Meeting
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Conference posterBruland, Torunn; Anderssen, Endre; Misund, Kristine; Beisvåg, Vidar; Sandvik, Arne K.; Lægreid, Astrid; Thommesen, Liv. (2009) Discovering basic network motifs that underlie gastrin induced gene expression. 10th international conference on system biology
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Conference lectureThommesen, Liv; Misund, Kristine; Selvik, Linn Karina Myrland; Lægreid, Astrid; Bruland, Torunn. (2009) NR4A" (Nurr1) - involved in gastrin-mediated carcinogenesis?. Contact meeting NBS
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Conference lectureBruland, Torunn; Anderssen, Endre; Misund, Kristine; Steigedal, Tonje Strømmen; Doseth, Berit; Langaas, Mette; Bergum, Hallgeir; Lægreid, Astrid; Thommesen, Liv. (2009) Basic common architectural motifs underlying gastrin induced gene expression can be identified by dimension reduction methods. Contact Meeting NBS
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Conference posterBruland, Torunn; Anderssen, Endre; Misund, Kristine; Beisvag, Vidar; Sandvik, Arne Kristian; Thommesen, Liv; Lægreid, Astrid. (2009) Discovering basic network motifs that underlie gastrin induced gene expression. The 10th International Conference on System Biology ICSB-2009, USA
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Conference lectureBruland, Torunn; Anderssen, Endre; Misund, Kristine; Steigedal, Tonje; Doseth, Berit; Fjeldbo, Christina Sæten; Langaas, Mette; Bergum, Hallgeir; Lægreid, Astrid; Thommesen, Liv. (2009) Basic common architectural motifs underlying gastrin induced gene expression can be identified by dimention reduction methods. NBS 43. Contact Meeting
2008
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Conference posterBruland, Torunn; Anderssen, Endre; Misund, Kristine; Steigedal, Tonje; Doseth, Berit; Fjeldbo, Christina Sæten; Langaas, Mette; Bergum, Hallgeir; Lægreid, Astrid; Thommesen, Liv. (2008) Significance analysis of gastrin-mediated transcription using dimension reduction methods for interpreting and modelling DNA microarray time series gene expression. 3rd ESF Functional Genomics Conference; Functional genomics and disease
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Conference posterBruland, Torunn; Anderssen, Endre; Misund, Kristine; Steigedal, Tonje; Doseth, Berit; Fjeldbo, Christina Sæten; Lægreid, Astrid; Thommesen, Liv. (2008) Molecular mechanisms in cancer related gastrin responses. Cancer Epigenetics Conference
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Conference posterSelvik, Linn-Karina M.; Misund, Kristine; Fjeldbo, Christina Sæten; Steigedal, Tonje Strømmen; Bruland, Torunn; Lægreid, Astrid; Thommesen, Liv. (2008) Salt-inducible kinase 1 (SIK1) is involved in the gastrin-mediated growth response. ESF Functional Genomics and Disease
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Conference posterBruland, Torunn; Andersen, Endre; Misund, Kristine; Steigedal, Tonje Strømmen; Fjeldbo, Christina Sæten; Lægreid, Astrid; Thommesen, Liv. (2008) Molecular mecanisms in cancer-related gastrin responses. Cancer Epigenetics
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Conference posterBruland, Torunn; Anderssen, Endre; Misund, Kristine; Steigedal, Tonje Strømmen; Doseth, Berit; Fjeldbo, Christina Sæten; Langaas, Mette; Bergum, Hallgeir; Lægreid, Astrid; Thommesen, Liv. (2008) Significance analysis of gastrin-mediated transcription using dimension reduction methods for interpreting and modelling DNA microarray time series gene expression data. ESF Functional Genomics and Disease
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Conference posterSelvik, Linn-Karina M.; Misund, Kristine; Fjeldbo, Christina Sæten; Steigedal, Tonje; Bruland, Torunn; Lægreid, Astrid; Thommesen, Liv. (2008) Salt-inducible kinase 1 (SIK1) is involved in the gastrin-mediated growth response. ESF Functional Genomics and Disease Conference
2007
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Conference lectureSæten, Christina; Misund, Kristine; Steigedal, Tonje; Otterlei, Marit; Lægreid, Astrid; Thommesen, Liv; Bruland, Torunn. (2007) Complex functional studies in mammalian cells using transfected cell arrays. The Norwegian Bichemical Society 43. Contact Meeting
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Conference lectureSteigedal, Tonje; Bruland, Torunn; Misund, Kristine; Thommesen, Liv; Lægreid, Astrid. (2007) Inducible cAMP early repressor (ICER) suppresses gastrin-mediated activation of cyclin D1 and c-fos gene expression. The Norwegian Bichemical Society 43. Contact Meeting
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Conference posterMisund, Kristine; Bruland, Torunn; Anderssen, Endre; Lægreid, Astrid; Thommesen, Liv. (2007) Global gene expression in HEK 293 cells with controllable ICER I and II gamma overexpression. NBS kontaktmøte 2007
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Conference posterMisund, Kristine; Hoel, Sunniva; Bruland, Torunn; Anderssen, Endre; Lægreid, Astrid; Thommesen, Liv. (2007) Global gene expression in HEK 293 cells with controllable ICER I and IIg - overexpression. Norsk Biokjemisk Selskaps 43. kontaktmøte
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Conference posterSæten, Christina; Misund, Kristine; Steigedal, Tonje Strømmen; Lægreid, Astrid; Thommesen, Liv; Bruland, Torunn. (2007) Complex functional studies in mammalian cells using transfected cell arrays. Norsk Biokjemisk Selskaps 43. kontaktmøte
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Conference posterSteigedal, Tonje Strømmen; Bruland, Torunn; Misund, Kristine; Thommesen, Liv; Lægreid, Astrid. (2007) Inducible cAMP early repressor (ICER) suppresses gastrin-mediated activation of cyclin D1 and c-fos gene expression. Norsk Biokjemisk Selskaps 43. kontaktmøte
2006
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Conference posterMisund, Kristine; Hoel, Sunniva; Bruland, Torunn; Anderssen, Endre; Lægreid, Astrid; Thommesen, Liv. (2006) Global gene expression in HEK 293 cells with controllable ICER I or IIgamma overexpression. The Seventh International Conference on Systems Biology; ICSB 2006
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Conference posterBruland, Torunn; Anderssen, Endre; Eitrem, Berit Doseth; Bergum, Hallgeir; Beisvåg, Vidar; Lægreid, Astrid. (2006) Optimization of cDNA microarrays procdures using optimization criteria that does not rely on an external standard. Poster presentation ICSB-2006 Japan
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Conference posterSteigedal, Tonje S.; Bruland, Torunn; Eitrem, Berit Doseth; Endre, Anderssen; Thommesen, Liv; Lægreid, Astrid. (2006) Systems Biology of Gastrointestinal Tumour BiologyStudies of gastrin mediated regulation of gene expression. The 7th International Conference on Systems Biology
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Conference lecture
2005
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Conference posterSteigedal, Tonje S.; Bruland, Torunn; Ween, Ola; Misund, Kristine; Thommesen, Liv; Lægreid, Astrid. (2005) Function of splice variants of the transcriptional repressor ICER in gastrin-mediated responses. The Norwegian Biochemical Society 41st Contact Meeting
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Conference posterBruland, Torunn; Eitrem, Berit Doseth; Anderssen, Endre; Beisvåg, Vidar; Lægreid, Astrid. (2005) Effects of choice and dose of dT blockers in cDNA microarray experiments. NBS Contact meeting
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Conference posterBruland, Torunn; Sæten, Christina; Strømmen, Tonje; Bergum, Hallgeir; Otterlei, Marit; Thommesen, Liv; Lægreid, Astrid. (2005) High-throughput characterisation of gene function using cell microarray. The2nd ESF Functional Genomic Conference, Oslo
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Conference lectureAnderssen, Endre; Bruland, Torunn; Ween, Ola; Langaas, Mette; Follestad, Turid; Lægreid, Astrid. (2005) Design and analysisi of microarray time series experiment. NBS Kontaktmøte 2005
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Conference lectureBruland, Torunn; Bergum, Hallgeir; Ween, Ola; Thommesen, Liv; Lægreid, Astrid. (2005) System biology of the normal and diseased gastrointestinal system: High-througput characterisation of gene function using cell microarray. 2nd ESF Function genomica and disease
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Conference lectureNørsett, K; Bruland, Torunn; Ween, Ola; Hofsli, Eva; Thommesen, Liv; Misund, Kristine; Strømmen, Tonje; Komorowski, Jan; Sandvik, Arne K.; Lægreid, Astrid. (2005) Systems biology of the normal and diseased gastrointestinal system. 2nd ESF Function genomics and disease
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Conference posterSteigedal, Tonje Strømmen; Bruland, Torunn; Ween, Ola; Misund, Kristine; Thommesen, Liv; Lægreid, Astrid. (2005) Function of splice variants of the transcriptional repressor ICER in gastrin-mediated reponses. NBS kontaktmøte
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Conference lectureLægreid, Astrid; Thommesen, Liv; Bruland, Torunn; Ween, Ola; Sandvik, Arne K.; Bergum, Hallgeir; Beisvåg, Vidar; Kusnierczyk, W; Aamodt, Agnar; Komorowski, Jan. (2005) System biology of the normal and diseased gastrointestinal system. 8th International meeting of microarray gene expression data society
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Conference lectureNørsett, Kristin; Bruland, Torunn; Ween, Ola; Hofsli, Eva; Thommesen, Liv; Misund, Kristine; Strømmen, Tonje; Kusnierczyk, Waclaw; Aamodt, Agnar; Midelfart, Herman. (2005) Systems biology of the normal and diseased gastrointestinal system. 2nd ESF Functional Genomics Conference
2004
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Conference posterMisund, Kristine; Stunes, Astrid Kamilla; Tømmerdal, Linda; Thommesen, Liv; Bruland, Torunn; Lægreid, Astrid. (2004) Constitutive expression of ICER in the cell-line HEK 293. Kontaktmøtet Norsk Biokjemisk Selskap 2004
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Conference lectureBruland, Torunn; Bergum, Hallgeir; Steigedal, Tonje; Otterlei, Marit; Thommesen, Liv; Lægreid, Astrid. (2004) Array based screening og gene function and cell-biological application of transfected-cell microarrays. NBS Kontaktmøte
2003
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Conference lectureThommesen, Liv; Bergum, Hallgeir; Langaas, Mette; Beisvåg, Vidar; Sandvik, Arne Kristian; Bruland, Torunn; Ween, Ola; Lægreid, Astrid. (2003) Rat Microarray Analysis Resources. Meetings on rat genomics and Models
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Conference lectureThommesen, Liv; Bergum, Hallgeir; Langaas, Mette; Beisvåg, Vidar; Sandvik, Arne K.; Bruland, Torunn; Ween, Ola; Lægreid, Astrid. (2003) Rat Microarray Analysis Resources. Meetings on rat genomics and Models
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LectureBruland, Torunn. (2003) Gene regulation in biological responses: HTP hypothesis testing. BIOEMIT prosjektmøte
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LectureBruland, Torunn. (2003) Gene regulation in biological responses: Focus on gastrin responses in neuroendocrine cells in the gastro-intestinal tract. BIOEMIT prosjektmøte
2001
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Lecture
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Conference lectureBruland, Torunn; Lavik, Liss Anne; Dai, Hong Yan; Dalen, Are. (2001) The influence of gender related factors upon susceptibility to Friend immunosuppressive virus (FIS-2) infection: Studies of primary target cells and hormonal regulation of virus replication. Virologisk kontaktmøte