MOL8001 - Molecular Physiology: Mechanisms and Methods


Examination arrangement

Examination arrangement: Oral examination
Grade: Passed / Not Passed

Evaluation Weighting Duration Grade deviation Examination aids
Oral examination 100/100

Course content

The course is targeted at PhD students and MD research-line students (Forskerlinjestudenter), included, but not limited to, the Faculty of Medicine and Health Sciences.

PhD is abbreviation of "Philosophiae doctor" in Latin or "Doctor of Philosophy" in English. "Phylosophia" is "love of wisdom" in Greek. Every student has individualized PhD program, and this course will focus on way of thinking, methodology and methods in general and on molecular, cellular and integrative physiology, biology and medicine in particular.

"Science is built up of facts, as a house is built of stones; but an accumulation of facts is no more a science than a heap of stones is a house." (Henri Poincaré ,1854-1912). Good PhD research is anchored on a sound research question(s) and follows a systematic, appropriate research methodology and methods to ensure that PhD thesis will make an original contribution to knowledge within the academic discipline. This course will provide basic knowledge about state-of-the-art technologies that can be used in either hypothesis-generation or hypothesis-driven research, particularly in understanding molecular mechanisms.

Learning outcome

After completing the course, the student

  • Will have an overview of research methodology in general, and systems biology and systems medicine in particular.
  • Will know how to perform next generation sequencing technology and applications.
  • Will know how to use single cell approaches to study normal and disease tissues.
  • Will understand systems biology, particularly from sequences to systems.
  • Will know how to perform mass spectrometry-based proteomics.
  • Will know approaches of tissue microarray, multi-omics, and stem cell technologies (e.g., organoids).
  • Will know approaches from cancer type to sequencing - the road to precision medicine.

Learning methods and activities

Lecturing will be a dominant teaching method. In addition, there will be exercise in groups and discussions with tutors on how to apply the methodology and methods in student’s own PhD research. The course can be flexible and have individual activities depending on number of registered students. Final exam will be an oral presentation of what the student has learned during the course. The student's effort during the course will also be considered in the exam evaluation.

Compulsory assignments

  • Lectures
  • Exercise (in group)

Further on evaluation

Compulsory assignments

  • Lectures
  • Exercise (in groups)

Compulsory activities from previous semester may be approved by the department.

Required previous knowledge

Admission requirements: Master degree or similar. Medical students at The Student Research Programme. Candidates with a lower degreee will be assessed individually. (Compare with Reccommended prev. knowledge)

Course materials

Reviews, original articles and prints of the lecture ppt with note pages.

More on the course



Version: 1
Credits:  4.5 SP
Study level: Doctoral degree level


Term no.: 1
Teaching semester:  AUTUMN 2023

Language of instruction: English

Location: Trondheim

Subject area(s)
  • Molecular Medicine
  • Medicine


Examination arrangement: Oral examination

Term Status code Evaluation Weighting Examination aids Date Time Examination system Room *
Autumn ORD Oral examination 100/100 2023-12-08 08:00
Room Building Number of candidates
Spring ORD Oral examination 100/100
Room Building Number of candidates
  • * The location (room) for a written examination is published 3 days before examination date. If more than one room is listed, you will find your room at Studentweb.

For more information regarding registration for examination and examination procedures, see "Innsida - Exams"

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