Duan Chen

About

Prof. Duan Chen (MD, PhD) is Principal Investigator of Research Group of Experimental Surgery and Pharmacology at Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU. He graduated from University of Lund, Sweden and is a professor at NTNU. He is member of Norwegian Academy of Technological Sciences and the Academy of Royal Norwegian Society of Sciences and Letters. He is past-chairman of Gastrointestinal Section of International Union of Basic and Clinical Pharmacology (IUPHAR). He is Associate Editor at Fronteirs in Pharmacology. He is Councilor of International Regulatory Peptide Society (IRPS).

Please see the links below for more details about his research

http://www.ntnu.no/dmf/ikm/molbiol

http://www.ntnu.edu/dmf/ikm/experimental-surgery

http://www.ntnu.edu/dmf/ikm/current-projects

Publications

2023

Chen, Duan; Hagen, Susan J; Boyce, Malcolm; Zhao, Chun Mei. (2023) Neuroendocrine mechanism of gastric acid secretion: Historical perspectives and recent developments in physiology and pharmacology. Journal of neuroendocrinology.
Academic article
Chen, Duan; Rehfeld, Jens Frederik; Watts, Alan G; Rorsman, Patrik; Gundlach, Andrew L.. (2023) History of key regulatory peptide systems and perspectives for future research. Journal of neuroendocrinology.
Academic article

2022

Brizozowski, Thomas; Sikiric, Predrag; Chen, Duan; Hahm, Ki-Baik; Seiwerth, Sven. (2022) Editorial: Protection and healing in the digestive system and other tissues: Novel factors, mechanisms, and pharmaceutical targets. Frontiers in Pharmacology. volum 13 (1116643).
Academic article

2021

Rabben, Hanne-Line; Andersen, Gøran Troseth; Ianevski, Aleksandr; Olsen, Magnus Kringstad; Kainov, Denis; Grønbech, Jon Erik; Wang, Timothy Cragin; Chen, Duan; Zhao, Chun-Mei. (2021) Computational Drug Repositioning and Experimental Validation of Ivermectin in Treatment of Gastric Cancer. Frontiers in Pharmacology. volum 12.
Academic article
Rabben, Hanne-Line; Andersen, Gøran Troseth; Olsen, Magnus Kringstad; Øverby, Anders; Ianevski, Aleksandr; Kainov, Denis; Wang, Timothy Cragin; Lundgren, Steinar; Grønbech, Jon Erik; Chen, Duan; Zhao, Chun-Mei. (2021) Neural signaling modulates metabolism of gastric cancer. iScience. volum 24 (2).
Academic article
Rabben, Hanne-Line; Kodama, Yosuke; Nakamura, Masahiko; Bones, Atle M.; Wang, Timothy Cragin; Chen, Duan; Zhao, Chun-Mei; Øverby, Anders. (2021) Chemopreventive Effects of Dietary Isothiocyanates in Animal Models of Gastric Cancer and Synergistic Anticancer Effects With Cisplatin in Human Gastric Cancer Cells. Frontiers in Pharmacology. volum 12.
Academic article

2020

Eiden, Lee E.; Gundlach, Andrew L.; Grinevich, Valery; Lee, Mary R.; Mecawi, André S.; Chen, Duan; Buijs, Ruud M.; Hernández, Vito S.; Fajardo-Dolci, Germán; Zhang, Li-Mei. (2020) Regulatory peptides and systems biology: A new era of translational and reverse-translational neuroendocrinology. Journal of neuroendocrinology. volum 00:e12844.
Academic literature review
Sheng, Weiwei; Ermanno, Malagola,; Henrik, Nienhüser; Zhengyu, Zhang; Woosook, Kim; Leah, Zamechek; Antonia, Sepulveda; Masahiro, Hata; Yoku, Hayakawa; Zhao, Chun-Mei; Chen, Duan; Timothy C., Wang. (2020) Hypergastrinemia Expands Gastric ECL Cells Through CCK2R Progenitor Cells via ERK Activation. Cellular and Molecular Gastroenterology and Hepatology (CMGH). volum 10 (2).
Academic article

2019

Guida, Claudia; Stephen, Sam D.; Watson, Michael; Dempster, Niall; Larraufie, Pierre; Marjot, Thomas; Cargill, Tamsin; Rickers, Lisa; Pavlides, Michael; Tomlinson, Jeremy; Cobbold, Jeremy F.L.; Zhao, Chun-Mei; Chen, Duan; Gribble, Fiona M; Reimann, Frank; Gillies, Richard; Sgromo, Bruno; Rorsman, Patrik; Ryan, John D. (2019) PYY plays a key role in the resolution of diabetes following bariatric surgery in humans. EBioMedicine. volum 40.
Academic article

2018

Chen, Duan; Ayala, Gustavo E. (2018) Innervating Prostate Cancer. New England Journal of Medicine. volum 378 (7).
Academic article
Guida, Claudia; McCulloch, Laura J.; Godazgar, Mahdieh; Stephen, Sam D.; Baker, Charlotte; Basco, Davide; Dong, Jiawen; Chen, Duan; Clark, Anne; Ramracheya, Reshma D.. (2018) Sitagliptin and Roux-en-Y gastric bypass modulate insulin secretion via regulation of intra-islet PYY. Diabetes, obesity and metabolism. volum 20 (3).
Academic article
Olsen, Magnus Kringstad; Johannessen, Helene; Ramracheya, Reshma; Zhao, Chun-Mei; Chen, Duan. (2018) New approaches for weight loss: Experiments using animal models. Current pharmaceutical design. volum 24 (18).
Academic literature review
Zhao, Chun-Mei; Rabben, Hanne-Line; Zhu, Yanping; Olsen, Magnus Kringstad; Wang, Zhiqiang; Hao, Yanpeng; Cai, Xing; Fonseca, Davi de Miranda; Sharma, Animesh; Li, Mingna; Zhihong, Zhang; Slupphaug, Geir; Wang, Timothy Cragin; Chen, Duan. (2018) 390 - A New Treatment for Pancreatic Cancer: Targeting Nervecancer Cell Crosstalk. Gastroenterology. volum 154.
Abstract

2017

Hayakawa, Yoku; Sakitani, Kosuke; Konishi, Mitsuru; Asfaha, Samuel; Niikura, Ryota; Tomita, Hiroyuki; Renz, Bernhard W.; Tailor, Yagnesh; Macchini, Marina; Middelhoff, Moritz; Jiang, Zhengyu; Tanaka, Takayuki; Dubeykovskaya, Zinaida A.; Kim, Woosook; Chen, Xiaowei; Urbanska, Aleksandra M.; Nagar, Karan; Westphalen, Christoph B.; Quante, Michael. (2017) Nerve growth factor promotes gastric tumorigenesis through aberrant cholinergic signaling. Cancer Cell. volum 31 (1).
Academic article
Olsen, Magnus Kringstad; Choi, Man Hung; Kulseng, Bård Eirik; Zhao, Chun-Mei; Chen, Duan. (2017) Time-restricted feeding on weekdays restricts weight gain: A study using rat models of high-fat diet-induced obesity. Physiology and Behavior. volum 173.
Academic article

2016

Johannessen, Helene; Revesz, David; Kodama, Yosuke; Cassie, Nikki; Skibicka, Karolina P.; Barrett, Perry; Dickson, Suzanne; Holst, Jens; Rehfeld, Jens; van der Plasse, Geoffrey; Adan, Roger; Kulseng, Bård Eirik; Ben-Menachem, Elinor; Zhao, Chun Mei; Chen, Duan. (2016) Vagal blocking for obesity control: a possible mechanism-of-action. Obesity Surgery. volum 27 (1).
Academic article
Cai, Xing; Rabben, Hanne-Line; Andersen, Gøran Troseth; Olsen, Magnus Kringstad; Øverby, Anders; Lundgren, Steinar; Grønbech, Jon Erik; Wang, Timothy C.; Chen, Duan; Zhao, Chun-Mei. (2016) A Potential New Regimen (“Tricyclie”) for Treatment of Gastric Cancer: Targeting Glutamine-Dependent Wnt/β-Catenin-mTOR Signaling. Gastroenterology. volum 150 (4).
Abstract
Chen, Duan; Olsen, Magnus Kringstad; Strømmen, Magnus; Johannessen, Helene; Bjøru, Hege Tevik; Salater, Sissel; Johnsen, Gjermund; Mårvik, Ronald; Zhao, Chun-Mei; Kulseng, Bård Eirik. (2016) Intragastric Injection of Botulinum Toxin a to Treat Obesity: Mechanism of Action and a Randomized, Double-Blind, Placebo-Controlled Phase II Trial With Open-Label Extension Study. Gastroenterology. volum 150 (4).
Abstract
Dubeykovskaya, Z; Si, Y; Chen, X; Worthley, DL; Renz, BW; Urbanska, AM; Hayakawa, Y; Xu, T; Westphalen, CB; Dubeykovskiy, A; Chen, Duan; Friedman, RA; Asfaha, S; Nagar, S; Tailor, Y; Muthupalani, S; Fox, JG; Kitajewski, J; Wang, Timothy C.. (2016) Neural innervation stimulates splenic TFF2 to arrest myeloid cell expansion and cancer. Nature Communications. volum 7 (10517).
Academic article
Johannesen, Helene; Revesz, David; Kodama, Yosuke; Cassie, Nikki; Skibicka, Karolina P.; Barrett, Perry; Dickson, Suzanne; Holst, Jens; Rehfeld, Jens F.; van der Plasse, Geoffrey; Adan, Roger; Kulseng, Bård Eirik; Ben-Menachem, Elinor; Zhao, Chun-Mei; Chen, Duan. (2016) Erratum to: Vagal Blocking for Obesity Control: a Possible Mechanism-Of-Action (OBES SURG, 10.1007/s11695-016-2278-x). Obesity Surgery. volum 27 (1).
Errata
Olsen, Magnus Kringstad; Johannessen, Helene; Cassie, Nikki; Barrett, Perry; Takeuchi, Koji; Kulseng, Bård Eirik; Chen, Duan; Zhao, Chun-Mei. (2016) Steady-state energy balance in animal models of obesity and weight loss. Scandinavian Journal of Gastroenterology. volum 52 (4).
Academic article
Rabben, Hanne-Line; Zhao, Chun-Mei; Hayakawa, Yoku; Wang, Timothy C.; Chen, Duan. (2016) Vagotomy and gastric tumorigenesis. Current Neuropharmacology. volum 14 (8).
Academic literature review
Ramracheya, Reshma D.; McCulloch, Laura J.; Clark, Anne; Wiggins, David; Johannessen, Helene; Olsen, Magnus Kringstad; Cai, Xing; Zhao, Chun-Mei; Chen, Duan; Rorsman, Patrik. (2016) PYY-Dependent Restoration of Impaired Insulin and Glucagon Secretion in Type 2 Diabetes following Roux-En-Y Gastric Bypass Surgery. Cell reports. volum 15 (5).
Academic article
Ramracheya, Reshma; McCulloch, Laura J.; Clark, Anne; Olsen, Magnus Kringstad; Zhao, Chun-Mei; Chen, Duan; Rorsman, Patrik. (2016) Roux-En-Y Gastric Bypass Surgery Restores Impaired Islet Architecture and Function in Type-2 Diabetes by Elevation of Plasma PYY. Gastroenterology. volum 150 (4).
Abstract
Øverby, Anders; Rabben, Hanne-Line; Takahashi, Tetsufumi; Zhao, Chun Mei; Matsui, Hidenori; Nakamura, Masahiko; Chen, Duan. (2016) Possible mechanism-of-action of naturally occurring isothiocyanates in chemoprevention and adjuvant chemotherapy for gastric cancer. Gastroenterology.
Abstract

2015

Andersen, Gøran Troseth; Kodama, Yosuke; Hayakawa, Yoku; Vettukattil, Riyas; Grønbech, Jon Erik; Chen, Duan; Zhao, Chun-Mei. (2015) 565Glutamine Metabolism As a Therapeutic Target for Gastric Cancer: Effects of Vagotomy Gastroenterology,Volume 148, Issue 4, Supplement 1, April 2015, Pages S-565–S-566. Gastroenterology. volum 148 (4).
Abstract
Boyce, Malcolm; Dowen, Sally; Turnbull, Gillian; van den Berg, Frans; Zhao, Chun-Mei; Chen, Duan; Black, James. (2015) Effect of netazepide, a gastrin/CCK2 receptor antagonist, on gastric acid secretion and rabeprazole-induced hypergastrinaemia in healthy subjectshypergastrinaemia in healthy subjects. British Journal of Clinical Pharmacology. volum 79 (5).
Academic article
Hayakawa, Yoku; Asfaha, Samuel; Renz, Bernhard W.; Westphalen, Christoph B.; Tailor,, Yagnesh H.; Nagar,, Karan K.; Worthley, Daniel L.; Chen, Duan; Wang, Timothy C.. (2015) NGF Promotes Gastrointestinal Cancer Development Through Tumor-Associated Neurogenesis. Gastroenterology. volum 148 (4).
Abstract
Hayakawa, Yoku; Jin, Guangchun; Wang, Hongshan; Chen, Xiaowei; Westphalen, Christoph B.; Asfaha, Samuel; Renz, Bernhard W.; Ariyama, Hiroshi; Dubeykovskaya, Zinaida A.; Takemoto, Yoshihiro; Lee, Yoomi; Muley, Ashlesha; Tailor, Yagnesh H.; Chen, Duan; Muthupalani, Sureshkumar; Fox, James G.; Shulkes, Arthur; Worthley, Daniel L.; Takaishi, Shigeo. (2015) CCK2R identifies and regulates gastric antral stem cell states and carcinogenesis. Gut. volum 64 (4).
Academic article
Olsen, Magnus Kringstad; Johannessen, Helene; Kodama, Yosuke; Kulseng, Bård Eirik; Zhao, Chun-Mei; Chen, Duan. (2015) Comparison of different surgical procedures in animal models for a better consideration of personalized bariatric surgery. Gastroenterology. volum 148 (4).
Abstract

2014

Chen, Duan. (2014) Skal teste Botox i kampen mot kreft. Sunnmørsposten.
publications.INTERVJUSKRIFTL
Dragsted, Lars Ove; Alexander, Jan; Amdam, Gro Vang; Bryan, Nathan S.; Chen, Duan; Haug, Anna; Karlsson, Anders H.; de Kok, Theo M.; Kulseng, Bård Eirik; Martin Jr, Roy J.; Milkowski, Andrew L.; Pajari, Anne-Maria; Pickova, Jana; Rudi, Knut; Sødring, Marianne Sundt; Oostindjer, Marije; Egelandsdal, Bjørg. (2014) Letter to the Editor: Colorectal cancer risk and association with red meat - Is it inconsistent? Answer to the letter by Corpet, De Smet and Demeyer. Meat Science. volum 98 (4).
Letter to the editor
Gudbrandsen, Oddrun Anita; Kodama, Yosuke; Mjøs, Svein Are; Zhao, Chun-Mei; Johannesen, Helene; Brattbakk, Hans-Richard; Haugen, Christine; Kulseng, Bård Eirik; Mellgren, Gunnar; Chen, Duan. (2014) Effects of duodenal switch alone or in combination with sleeve gastrectomy on body weight and lipid metabolism in rats. Nutrition and Diabetes. volum 4 (JUNE).
Academic article
Johannessen, Helene; Olsen, Magnus Kringstad; Cassie, Nikki; Barrett, Perry; Rehfeld, Jens F.; Holst, Jens J.; Kulseng, Bård Eirik; Zhao, Chun-Mei; Chen, Duan. (2014) Preclinical Trial of Gastric Injection of Botulinum Toxin Type A as Weight-Loss-Surgery. Gastroenterology. volum 146 (5).
Abstract
Okabe, Susumu; Okamoto, Toshihiro; Zhao, Chun-Mei; Chen, Duan; Matsui, Hirofumi. (2014) Acetic acid induces cell death: An in vitro study using normal rat gastric mucosal cell line and rat and human gastric cancer and mesothelioma cell lines. Journal of Gastroenterology and Hepatology. volum 29 (S4).
Academic article
Oostindjer, Marije; Alexander, Jan; Amdam, Gro Vang; Andersen, Grethe; Bryan, Nathan S.; Chen, Duan; Corpet, Denis E.; De Smet, Stefaan; Dragsted, Lars Ove; Haug, Anna; Karlsson, Anders H.; Kleter, Gijs; de Kok, Theo M.; Kulseng, Bård Eirik; Milkowski, Andrew L.; Martin, Roy; Pajari, Anne-Maria; Paulsen, Jan Erik; Pickova, Jana. (2014) The role of red and processed meat in colorectal cancer development: a perspective. Meat Science. volum 97 (4).
Academic literature review
Zhao, Chun-Mei; Hayakawa, Yoku; Kodama, Yosuke; Muthupalani, Sureshkumar; Westphalen,, Christoph B.; Andersen, Gøran Troseth; Flatberg, Arnar; Johannessen, Helene; Friedman, Richard A.; Renz, Bernhard W.; Sandvik, Arne Kristian; Beisvag, Vidar; Tomita, Hiroyuki; Hara, Akira; Quante, Michael; Li, Zhishan; Gershon, Michael D.; Kaneko, Kazuhiro; Fox,, James G.. (2014) Denervation suppresses gastric tumorigenesis. Science Translational Medicine. volum 6 (250).
Academic article
Zhao, Chun-Mei; Kodama, Yosuke; Flatberg, Arnar; Beisvag, Vidar; Kulseng, Bård Eirik; Sandvik, Arne Kristian; Rehfeld, Jens F.; Chen, Duan. (2014) Gene expression profiling of gastric mucosa in mice lacking CCK and gastrin receptors. Regulatory Peptides. volum 192-193.
Academic article
Zhao, Chun-Mei; Mark, Kidd,; Chen, Duan. (2014) Triple Roles of Autophagy in Cytoprotection, Cell Death and Tumorigenesis With Special Reference to Gastric ECL Cells. Gastroenterology. volum 146 (5).
Abstract
Zhao, Chun-Mei; Myrvold, Helge Elliot; Chen, Duan. (2014) Reduced neurons in the ileum of proctocolectomized rat models. Medical Molecular Morphology. volum 48 (3).
Academic article
Zhao, Chun-Mei; Yoku, Hayakawa; Westphalen,, Christoph B; Muthupalani,, Sureshkumar; Johannessen, Helene; Andersen, Gøran Troseth; Fox,, James G; Wang,, Timothy C.; Chen, Duan. (2014) Preclinical Trial of Botulinum Toxin Type a Injection in the Treatment of Gastric Cancer. Gastroenterology. volum 146 (5).
Abstract
Øverby, Anders; Zhao, Chun-Mei; Bones, Atle M.; Chen, Duan. (2014) Naturally occurring phenethyl isothiocyanate-induced inhibition of gastric cancer cell growth by disruption of microtubules. Journal of Gastroenterology and Hepatology. volum 29 (4).
Academic article
Øverby, Anders; Zhao, Chun-Mei; Chen, Duan. (2014) Plant phytochemicals: Potential anticancer agents against gastric cancer. Current opinion in pharmacology (Print). volum 19.
Academic article
Øverby, Anders; Zhao, Chun-Mei; Wang, Timothy C.; Bones, Atle M.; Chen, Duan. (2014) Gastric cancer chemoprevention by phenethyl isothiocyanate-containing diet in chemically - but not genetically - induced gastric cancer in mice. Gastroenterology. volum 146.
Abstract

2013

Johannessen, Helene; Revesz, David; Kodama, Yosuke; Cassie, Nikki; Skibicka, Karolina P.; Lyle, Robert; Bettencourt, Paulo; Miroljub, Popovic; Witter, Menno; Barrett, Perry; Dickson, Suzanne L.; Koji, Takeuchi; Kulseng, Bård; Thorlin, Thorleif; Ben-Menachem, Elinor; Zhao, Chun-Mei; Chen, Duan. (2013) Role of the vagus nerve in the gut-brain axis revealed by stimulation and blockade of the gastric vagus nerve. Gastroenterology. volum 144 (5).
Abstract
Kodama, Yosuke; Johannessen, Helene; Furnes, Marianne Waldum; Zhao, Chun-Mei; Johnsen, Gjermund; Mårvik, Ronald; Kulseng, Bård; Chen, Duan. (2013) Mechanistic Comparison between Gastric Bypass vs. Duodenal Switch with Sleeve Gastrectomy in Rat Models. PLOS ONE. volum 8 (9).
Academic article
Kodama, Yosuke; Zhao, Chun-Mei; Muthupalani, Sureshkumar; Flatberg, Arnar; Friedman, Richard A.; Sandvik, Arne; Beisvag, Vidar; Johannessen, Helene; Hayakawa, Yoku; Tomita, Hiroyuki; Hara, Akira; Westphalen, Christoph B.; Quante, Michael; Kaneko, Kazuhiro; Fox, James G.; Wang, Timothy C.; Chen, Duan. (2013) Denervation Suppresses Gastric Cancer Initiation and Progression Through Inhibition of the Cancer Niche. Gastroenterology. volum 144 (5).
Abstract
Zhao, Chun-Mei; Johannessen, Helene; Kodama, Yosuke; Kulseng, Bård; Chen, Duan. (2013) Galanin. Handbook of Biologically Active Peptides.
Chapter
Chen, Duan; Zhao, Chun-Mei. (2013) Signaling pathways in control of gastric acid secretion and food-stomach-bone axis revealed by gene expression profiling in the stomach of genetically targeted mice deficient in CCK1 receptor and gastrin/CCK2 receptor. The FASEB Journal. volum 27:1093.25.
Abstract
Johannessen, Helene; Kodama, Yosuke; Zhao, Chun-Mei; Sousa, Mirta; Slupphaug, Geir; Kulseng, Bård Eirik; Chen, Duan. (2013) Eating Behavior and Glucagon-Like Peptide-1-Producing Cells in Interposed Ileum and Pancreatic Islets in Rats Subjected to Ileal Interposition Associated with Sleeve Gastrectomy. Obesity Surgery. volum 23 (1).
Academic article
Vigen, Alexander; Kodama, Yosuke; Viset, Trond; Fossmark, Reidar; Waldum, Helge; Kidd, Mark; Wang, Timothy C.; Modlin, Irvin; Chen, Duan; Zhao, Chun-Mei. (2013) Immunohistochemical evidence for an impairment of autophagy in tumorigenesis of gastric carcinoids and adenocarcinomas in rodent models and patients. Histology and Histopathology. volum 28 (4).
Academic article

2012

Okabe, Susumu; Kodama, Yosuke; Cao, HaiLong; Johannessen, Helene; Zhao, Chun-Mei; Wang, TC; Takahashi, Rei; Chen, Duan. (2012) Topical application of acetic acid in cytoreduction of gastric cancer model in mice. A technical report. Journal of Gastroenterology and Hepatology. volum 27 (s3).
Academic article
Chen, Duan; Zhao, Chun-Mei. (2012) Importance of Translational Research in GI Pharmacology: Lessons Learned from the Successes in History. Frontiers of gastrointestinal research. volum 30.
Academic article
Erlandsen, Sten Even; Qvigstad, Gunnar; Fossmark, Reidar; Bakke, Ingunn; Chen, Duan; Sandvik, Arne Kristian. (2012) Regulated endocrine-specific protein 18 (RESP18) is localized to and regulated in A-like cells and G-cells in rat stomach. Regulatory Peptides. volum 177 (1-3).
Academic article
Johannessen, Helene; Kodama, Yosuke; Zhao, Chun-Mei; Johnsen, Gjermund; Mårvik, Ronald; Kulseng, Bård Eirik; Chen, Duan. (2012) Evidence for the Hindgut Hypothesis After Ileal Interposition Associated With Sleeve Gastrectomy: Increased Number of GLP-1-Producing Cells in Interposed Ileum and Pancreatic Islets in Rats. Gastroenterology. volum 142 (5).
Abstract
Johannessen, Helene; Kodama, Yosuke; Zhao, Chun-Mei; Johnsen, Gjermund; Mårvik, Ronald; Kulseng, Bård Eirik; Chen, Duan; Revesz, David; Kuhn, Georg; Thorlin, Thorleif; Ben-Menachem, Elinor. (2012) Altered Eating Behavior by Subdiaphragmatic Truncal Vagus Nerve Stimulation in Rats. Gastroenterology. volum 142 (5).
Abstract
Kodama, Yosuke; Flatberg, Arnar; Anderssen, Endre; Sandvik, Arne Kristian; Chen, Duan; Zhao, Chun-Mei. (2012) Food Intake Associated Gene Expression Profiles in the Stomach of Genetically Targeted Mice Deficient in CCK1 Receptor and/or CCK2 Receptor. Gastroenterology. volum 142 (5).
Abstract
Kodama, Yosuke; Johannessen, Helene; Furnes, Marianne Waldum; Zhao, Chun-Mei; Johnsen, Gjermund; Mårvik, Ronald; Kulseng, Bård Eirik; Chen, Duan. (2012) Gastric Bypass and Duodenal Switch Cause Body Weight Loss Through Different Mechanisms in Rats. Gastroenterology. volum 142 (5).
Abstract
Kodama, Yosuke; Zhao, Chun-Mei; Quante, Michael; Muthupalani, Sureshkumar; Flatberg, Arnar; Friedman, Richard A.; Sandvik, Arne Kristian; Fox, James G.; Kaneko, Kazuhiro; Wang, Timothy C.; Chen, Duan. (2012) Vagotomy Suppresses Gastric Cancer Progression in Mice. Gastroenterology. volum 142 (5).
Abstract
Liu, Yanhua; Zhu, Lijun; Pan, Ya; Sun, Lizhou; Chen, Duan; Li, Xiaonan. (2012) Adiponectin Levels in Circulation and Breast Milk and mRNA Expression in Adipose Tissue of Preeclampsia Women. Hypertension in Pregnancy. volum 31 (1).
Academic article
Vigen, Alexander; Chen, Duan; Zhao, Chun-Mei. (2012) Pathobiology of Gastric Carcinoids and Adenocarcinomas in Rodent Models and Patients: Studies of Gastrocystoplasty, Gender-Related Factors and Autophagy. Frontiers of gastrointestinal research. volum 30.
Academic article
Vigen, Alexander; Kidd, Mark; Modlin, IM; Chen, Duan; Zhao, Chun-Mei. (2012) Ultrastructure of ECL cells in Mastomys after long-term treatment with H-2 receptor antagonist loxtidine. Medical Molecular Morphology. volum 45 (2).
Academic article
Vigen, Alexander; Kodama, Yosuke; Viset, Trond; Fossmark, Reidar; Waldum, Helge; Kidd, Mark; Wang, Timothy C.; Modlin, Irvin; Chen, Duan; Zhao, Chun-Mei. (2012) Impaired Autophagy in Gastric Carcinoids and Adenocarcinoma of Both Rodent Models and Patients. Gastroenterology. volum 142 (5).
Abstract
Vigen, Reidar Alexander; Arum, Carl-Jørgen; Viset, Trond; Chen, Duan; Zhao, Chun-Mei. (2012) Experimental gastrocystoplasty in rats: Risk of developing ECLoma. Journal of Pediatric Urology. volum 8 (2).
Academic article
Zhao, Chun-Mei; Chen, Duan. (2012) The ECL Cell: Relay Station for Gastric Integrity. Current Medicinal Chemistry. volum 19 (1).
Academic literature review

2011

Johannessen, Helene; Kodama, Yosuke; Cao, HaiLong; Kulseng, Baard; Zhao, Chun-Mei; Chen, Duan. (2011) Eating Behavior in Rats Subjected to Ileum Transposition and Sleeve Gastrectomy. Gastroenterology. volum 140 (5).
Abstract
Zhao, Chun-Mei; Kodama, Yosuke; Flatberg, Arnar; Sandvik, Arne Kristian; Chen, Duan. (2011) Stomach-Bone Axis: Possible Involvement of Signaling Pathways and Vitamin D Governing Bone Metabolism. Gastroenterology. volum 140 (5).
Abstract
Arum, Carl-Jørgen; Gederaas, Odrun Arna; Larsen, Eivind La Puebla; Randeberg, Lise Lyngsnes; Hjelde, Astrid; Krokan, Hans Einar; Svaasand, Lars O.; Chen, Duan; Zhao, Chun-Mei. (2011) Tissue responses to hexyl 5-aminolevulinate-induced photodynamic treatment in syngeneic orthotopic rat bladder cancer model: possible pathways of action. Journal of Biomedical Optics. volum 16 (2).
Academic article
Cao, HaiLong; Xue, L; Xu, X; Wu, Y; Zhu, J; Chen, L; Chen, Duan; Chen, YJ. (2011) Heat shock proteins in stabilization of spontaneously restored sinus rhythm in permanent atrial fibrillation patients after mitral valve surgery. Cell stress & chaperones (Print). volum 16 (5).
Academic article
Cao, HaiLong; Xue, L; Xu, X; Wu, Y; Zhu, J; Chen, L; Chen, Duan; Chen, YJ. (2011) Heat shock proteins in stabilization of spontaneously restorted sinus rhythm in permanent atrial fibrillation patients after mitral valve surgery. Cell stress & chaperones (Print). volum 16 (5).
Academic article
Chen, D; Truong, T; Gaborieau, V; Byrnes, G; Chabrier, A; Chuang, SC; Olshan, AF; Weissler, MC; Luo, JC; Romkes, M; Buch, S; Nukui, T; Franceschi, S; Herrero, R; Talamini, R; Kelsey, KT; Christensen, B; McClean, MD; Lacko, M. (2011) A Sex-Specific Association between a 15q25 Variant and Upper Aerodigestive Tract Cancers. Cancer Epidemiology, Biomarkers and Prevention. volum 20 (4).
Academic article
Chen, Duan; Zhao, Chun-Mei. (2011) The possible existence of a gut-bone axis suggested by studies of genetically manipulated mouse models?. Current pharmaceutical design. volum 17 (16).
Academic literature review
Cui, Fei; Wang, Jian; Chen, Duan; Chen, Yi-Jiang. (2011) CD133 is a temporary marker of cancer stem cells in small cell lung cancer, but not in non-small cell lung cancer. Oncology Reports. volum 25 (3).
Academic article
Hutchinson, Lloyd; Stenström, Björn; Chen, Duan; Piperdi, Bilal; Levey, Sara; Lyle, Stephen; Wang, Timothy C.; Houghton, J. (2011) Human Barrett's adenocarcinoma of the esophagus, associated myofibroblasts, and endothelium can arise from bone marrow-derived cells after allogeneic stem cell transplant. Stem Cells and Development. volum 20 (1).
Academic article
Kodama, Yosuke; Johannessen, Helene; Furnes, Marianne Waldum; Zhao, Chun-Mei; Kulseng, Bård Eirik; Chen, Duan. (2011) Energy Metabolism Following High-Fat Diet and Bariatric Surgeries (Gastric Bypass, Sleeve Gastrectomy, Duodenal Switch and Ileum Transposition) in Rats. Gastroenterology. volum 140 (5).
Abstract
Kodama, Yosuke; Zhao, Chun-Mei; Quante, Michael; Muthupalani, Sureshkumar; Flatberg, Arnar; Sandvik, Arne Kristian; Fox, James G.; Wang, Timothy C.; Chen, Duan. (2011) Evidence for Mechanism of Vagal Innervation in Gastric Cancer Initiation Involving Signaling Pathways Governing Stem Cells in Mice. Gastroenterology. volum 140 (5).
Abstract
Salome, N; Taube, M; Egecioglu, E; Hansson, C; Karlsson, Bjørn; Chen, Duan; Andersson, DR; Georg-Kuhn, H; Ohlsson, C; Dickson, SL. (2011) Gastrectomy alters emotional reactivity in rats: neurobiological mechanisms. European Journal of Neuroscience. volum 33 (9).
Academic article
Vigen, Reidar Alexander; Chen, Duan; Syversen, Unni; Stunes, Astrid Kamilla; Håkanson, Rolf; Zhao, Chun-Mei. (2011) Serum gastrin and gastric enterochromaffin-like cells during estrous cycle, pregnancy and lactation, and in response to estrogen-like agents in rats. Journal of Physiology and Pharmacology. volum 62 (3).
Academic article
Vigen, Reidar Alexander; Kidd, Mark; Modlin, Irvin; Chen, Duan; Zhao, Chun-Mei. (2011) Ultrastructral Evidence for a Mechanism of ECL Cell Transformation to Gastric Carcinoid in Mastomys Involving Impairment of Autophagy and Loss of Gastrin Control. Gastroenterology. volum 140 (5).
Abstract

2010

Westerberg, I.; Walther, A; Guerrero, J-L; Coello, Z; Halldin, S; Xu, Chong-Yu; Chen, D; Lundin, L-C. (2010) Precipitation data in a mountainous catchment in Honduras: quality assessment and spatiotemporal characteristics. Theoretical and Applied Climatology. volum 101 (3-4).
Academic article
Arum, Carl-Jørgen; Anderssen, Endre; Tømmerås, Karin; Lundgren, Steinar; Chen, Duan; Zhao, Chun-Mei. (2010) Gene Expression Profiling and Pathway Analysis of Superficial Bladder Cancer in Rats. Urology. volum 75 (3).
Academic article
Arum, Carl-Jørgen; Anderssen, Endre; Viset, Trond; Kodama, Yosuke; Lundgren, Steinar; Chen, Duan; Zhao, Chun-Mei. (2010) Cancer Immunoediting from Immunosurveillance to Tumor Escape in Microvillus-Formed Niche: A Study of Syngeneic Orthotopic Rat Bladder Cancer Model in Comparison with Human Bladder Cancer. Neoplasia. volum 12 (6).
Academic article
Arum, Carl-Jørgen; Kodama, Yosuke; Rolim, Natale Pinheiro Lage; Widerøe, Marius; Anderssen, Endre; Viset, Trond; Otterlei, Marit; Lundgren, Steinar; Chen, Duan; Zhao, Chun-Mei. (2010) A rat model of intravesical delivery of small interfering RNA for studying urinary carcinoma. World Journal of Urology. volum 28 (4).
Academic article
Chen, Duan; Zhao, Chun-Mei. (2010) Complexity of Gastric Acid Secretion Revealed by Targeted Gene Disruption in Mice. Current pharmaceutical design. volum 16 (10).
Academic literature review
Kodama, Yosuke; Zhao, Chun-Mei; Kulseng, Baad; Chen, Duan. (2010) Eating Behavior in Rats Subject to Vagotomy, Sleeve Gastrectomy and Duodenal Switch. Gastroenterology. volum 14.
Academic article
Kodama, Yosuke; Zhao, Chun-Mei; Kulseng, Bård Eirik; Chen, Duan. (2010) Eating Behavior in Rats Subjected to Vagotomy, Sleeve Gastrectomy, and Duodenal Switch. Journal of Gastrointestinal Surgery. volum 14 (10).
Academic article
Kodama, Yosuke; Zhao, Chun-Mei; Quante, Michael; Muthupalani, Sureshkumar; Fox, James G.; Wang, Timothy C.; Chen, Duan. (2010) Truncal vagotomy inhibited gastric cancer initiation in the INS-GAS mouse model. Gastroenterology. volum 136.
Abstract
Song, Zhigang; Bhagat, Govind; Quante, Michael; Baik, Gwang Ho; Marrache, Frederic; Tu, Shuiping; Zhao, Chun-Mei; Chen, Duan; Dannenberg, Andrew; Wang, Timothy C.. (2010) Potential carcinogenic effects of cigarette smoke and Swedish moist snuff on pancreas: a study using a transgenic mouse model of chronic pancreatitis. Laboratory Investigation. volum 90 (3).
Academic article
Zhao, Chun-Mei; Kodama, Yosuke; Flatberg, Arnar; Anderssen, Endre; Sandvik, Arne Kristian; Chen, Duan. (2010) Gastric ECL cells, rather than gastric acid, play an important role in gut-bone axis. Gastroenterology. volum 136.
Abstract
Zheng, Liang; Xu, Jing; Qiu, Wanshan; Liu, Xiang; Zhao, Chun-Mei; Chen, Duan; Chen, Yi-Jiang. (2010) CARDIOPROTECTION OF EXOGENOUS ERYTHROPOIETIN IN MICE WITH LIGATURE-INDUCED AORTIC STENOSIS: EFFECTS ON MALADAPTIVE CARDIAC HYPERTROPHY. Journal of Physiology and Pharmacology. volum 61 (1).
Academic article

2009

Arum, Carl-Jørgen; Anderssen, Endre; Tømmerås, Karin; Zhao, Chun-Mei; Chen, Duan. (2009) Gene expression profiles of bladder cancer: Comparison between orthotopic rat bladder cancer model and human bladder cancer patients. European Urology. Supplement. volum 8 (4).
Abstract
Chen, Duan; Furnes, Marianne Waldum; Zhao, Chun-Mei. (2009) Translational research on obesity: from bedside to bench. Journal of Physiology and Pharmacology. volum 60.
Academic article
Furnes, Marianne Waldum; Zhao, Chun-Mei; Chen, Duan. (2009) Development of Obesity is Associated with Increased Calories per Meal Rather than per Day. A Study of High-Fat Diet-Induced Obesity in Young Rats. Obesity Surgery. volum 19 (10).
Academic article
Furnes, Marianne; Zhao, Chun-Mei; Stenstrøm, Bjørn; Arum, Carl-Jørgen; Tømmerås, Karin; Kulseng, Bård Eirik; Chen, Duan. (2009) Feeding behavior and body weight development: Lessons from rats subjected to gastric bypass surgery or high-fat diet. Journal of Physiology and Pharmacology. volum 60.
Academic article
Song, Zhigang; Bhagat, Govind; Baik, Gwang Ho; Gordon, Shanisha A.; Mitchell, Anthony; Zhao, Chun-Mei; Chen, Duan; Dannenberg,, Andrew; Wang, Timothy C.. (2009) Development of a Mouse Model of Inflammation-Dependent Pancreatic Cancer. Gastroenterology. volum 136 (5).
Academic article
Zhao, Chun-Mei; Anderssen, Endre; Chen, Duan. (2009) Gene Expression and Pathway Analysis of Mouse Stomach: Gastric ECL Cells May Produce Vitamin D. Gastroenterology. volum 136 (5).
Academic article
Zhao, Chun-Mei; Kodama, Yosuke; Sandvik, Arne Kristian; Chen, Duan. (2009) Differentiation of Gastric ECL Cells in CCK 1+2 Receptor Double Knockout Mice. Gastroenterology. volum 136 (5).
Academic article

2008

Qiu, Wanshan; Gu, Haiyong; Zheng, Liang; Zhou, Jianwei; Chen, Duan; Chen, Yijiang. (2008) Pretreatment with edaravone reduces lung mitochondrial damage in an infant rabbit ischemia-reperfusion model. Journal of Pediatric Surgery. volum 43 (11).
Academic article
Qiu, Wanshan; Zheng, Liang; Gu, Haiyong; Chen, Duan; Chen, Yijiang. (2008) Comparison between adult and infant lung injury in a rabbit ischemia-reperfusion model. Journal of Thoracic and Cardiovascular Surgery. volum 136 (2).
Academic article
Zhao, Chun-Mei; Furnes, Marianne Waldum; Stenström, Björn; Kulseng, Bård Eirik; Chen, Duan. (2008) Characterization of obestatin- and ghrelin-producing cells in the gastrointestinal tract and pancreas of rats: an immunohistochemical and electron-microscopic study. Cell and Tissue Research. volum 331 (3).
Academic article
Bernsand, Maria; Zhao, Chun-Mei; Chen, Duan; Håkanson, R; Stenstrøm, Bjørn; Norlén, Per. (2008) Ischemia mobilizes histamine but not pancreastatin from ECL cells of rat stomach: evidence for a cytosolic histamine compartment. Cell and Tissue Research. volum 333 (3).
Academic article
Egecioglu, E; Stenstrom, B; Pinnock, SB; Tung, LYC; de la Cour, CD; Lindqvist, A; Hakanson, R; Syversen, Unni; Chen, Duan; Dickson, SL. (2008) Hypothalamic gene expression following ghrelin therapy to gastrectomized rodents. Regulatory Peptides. volum 146.
Academic article
Furnes, Marianne Waldum; Stenstrøm, Bjørn; Tømmerås, Karin; Skoglund, Trine; Dickson, SL; Kulseng, Bård Eirik; Zhao, Chun-Mei; Chen, Duan. (2008) Feeding behaviour in rats subjected to gastrectomy or gastric bypass surgery. European Surgical Research. volum 40 (3).
Academic article
Furnes, Marianne Waldum; Tømmerås, Karin; Arum, Carl-Jørgen; Zhao, Chun-Mei; Chen, Duan. (2008) Gastric bypass surgery causes body weight loss without reducing food intake in rats. Obesity Surgery. volum 18.
Academic article
Larsen, Eivind La Puebla; Randeberg, Lise Lyngsnes; Gederaas, Odrun Arna; Arum, Carl-Jørgen; Hjelde, Astrid; Zhao, Chun-Mei; Chen, Duan; Krokan, Hans Einar; Svaasand, Lars O.. (2008) Monitoring of Hexyl 5-aminolevulinate Induced Photodynamic Therapy in Rat Bladder Cancer by Optical Spectroscopy. Journal of Biomedical Optics. volum 13 (4).
Academic article
Zhao, Chun-Mei; Martinez, V; Piqueras, L; Wang, L-X; Taché, Y; Chen, Duan. (2008) Control of gastric acid secretion in somatostatin receptor 2 deficient mice: shift from endocrine/paracrine to neurocrine pathways. Endocrinology. volum 149 (2).
Academic article

2007

Arum, Carl-Jørgen; Tømmerås, Karin; Anderssen, Endre; Zhao, Chun-Mei; Chen, Duan. (2007) Gene expression profiling and pathway analysis of orthotopic rat bladder cancer model. European Urology. Supplement. volum 6.
Abstract
Chen, Duan; Karlsson, Bjørn; Zhao, Chun-Mei; Wadstrom, T. (2007) Does Helicobacter pylori infection per se cause gastric cancer or duodenal ulcer? Inadequate evidence in Mongolian gerbils and inbred mice. FEMS Immunology and Medical Microbiology. volum 50.
Academic article
Chen, Duan; Zhao, Chun-Mei. (2007) Genetically engineered mice: a new paradigm to study gastric physiology. Current Opinion in Gastroenterology. volum 23.
Academic article
Egecioglu, E; Karlsson, Bjørn; Pinnock, S B; Tung, LYC; Dornonville de la Cour, C; Lindqvist, A; Håkanson, R; Syversen, Unni; Chen, Duan; Dickson, SL. (2007) Hypothalamic gene expression following ghrelin therapy to gastrectomized rodents. Regulatory Peptides. volum 14.
Academic article
Karlsson, Bjørn; Zhao, Chun-Mei; Rogers, AB; Nilsson, HO; Sturegard, E; Lundgren, Steinar; Fox, J; Wang, Timothy C.; Chen, Duan; Wadstrom, T. (2007) Swedish moist snuff accelerates gastric cancer development in Helicobacter pylori-infected wild-type and gastrin transgenic mice. Carcinogenesis. volum 28.
Academic article
Zhao, Chun-Mei; Chen, Duan. (2007) Genetically engineered mice: a new paradigm to study gastric physiology. Stomach and duodenum. Current Opinion in Gastroenterology. volum 23 (6).
Academic article

2006

Chen, Duan; Aihara, Takeshi; Zhao, Chun-Mei; Håkanson, Rolf; Okabe, Susumu. (2006) Differentiation of the Gastric Mucosa I. Role of histamine in control of function and integrity of oxyntic mucosa: understanding gastric physiology through disruption of targeted genes. American Journal of Physiology - Gastrointestinal and Liver Physiology. volum 291.
Academic article
Zhao, Chun-Mei; Chen, Duan; Stenström, Björn. (2006) Does Helicobacter pylori infection per se cause gastric cancer and/or duodenal ulcer in Mongolian gerbils and wild-type mice? A critical micro-review. FEMS Immunology and Medical Microbiology.
Academic article
Fykse, Vidar; Solligård, Erik; Bendheim, Marianne Østensen; Chen, Duan; Grønbech, Jon Erik; Sandvik, Arne Kristian; Waldum, Helge. (2006) ECL cell histamine mobilization and parietal cell stimulation in the rat stomach studied by microdialysis and electron microscopy. Acta Physiologica. volum 186.
Academic article
Larsen, Eivind La Puebla; Randeberg, Lise Lyngsnes; Gederaas, Odrun Arna; Arum, Carl-Jørgen; Krokan, Hans Einar; Chen, Duan; Hjelme, Dag Roar; Svaasand, Lars O.. (2006) Monitoring of hALA induced PDT in rat bladder cancer by optical spectroscopy. Lasers in Surgery and Medicine.
Abstract
Stenstrøm, Bjørn Olof; Zhao, Chun-Mei; Tømmerås, Karin; Arum, Carl-Jørgen; Chen, Duan. (2006) Is gastrin partially responsible for body weight reduction after gastric bypass?. European Surgical Research. volum 38.
Academic article
Stenstrøm, Bjørn; Furnes, Marianne Waldum; Tømmerås, Karin; Syversen, Unni; Zhao, Chun-Mei; Chen, Duan. (2006) Mechanism of gastric bypass-induced body weight loss: One-year follow-up after micro-gastric bypass in rats. Journal of Gastrointestinal Surgery. volum 10 (10).
Academic article
Vigen, RA; Arum, Carl-Jørgen; Karlsson, Bjørn; Chen, Duan. (2006) A unique surgical model for studying the physiology of gastrin: Gastrocystoplasty and fundectomy. Scandinavian Journal of Laboratory Animal Science. volum 33.
Academic article

2005

Arum, Carl-Jørgen; Vigen, RA; Karlsson, Bjørn; Tømmerås, Karin; Zhao, Chun-Mei; Chen, Duan. (2005) Acid secretion in urinary bladder of rats subjected to gastrocystoplasty. InflammoPharmacology. volum 13.
Academic article
Chen, Duan; Friis-Hansen, L; Håkanson, R; Zhao, Chun-Mei. (2005) Genetic dissection of the signaling pathways that control gastric acid secretion. InflammoPharmacology. volum 13.
Academic literature review
Martinsen, Tom Christian; Bakke, Ingunn; Chen, Duan; Sandvik, Arne Kristian; Zahlsen, Kolbjørn; Aamo, T.; Waldum, Helge. (2005) Ciprofibrate stimulates the gastrin-producing cell by acting luminally on antral PPAR-alfa. American Journal of Physiology - Gastrointestinal and Liver Physiology. volum 289.
Academic article
Zhao, Chun-Mei; Fossmark, Reidar; Martinsen, Tom Christian; Kawase, Shiro; Chen, Duan; Waldum, Helge. (2005) Dedifferentiation of enterochromaffin-like cells in gastric cancer of hypergastrinemic cotton rats. APMIS - Journal of Pathologiy, Microbiology and Immunology. volum 113.
Academic article
Zhao, Chun-Mei; Håkanson, Rolf; Chen, Duan. (2005) Secretory organelles in ECL cells: effects of pharmacological blockade of the gastrin/CCK2 receptor versus its elimination by gene targeting. InflammoPharmacology. volum 13.
Academic literature review
Fossmark, Reidar; Zhao, Chun-Mei; Martinsen, Tom Christian; Kawase, Shiro; Chen, Duan; Waldum, Helge. (2005) Dedifferentiation of enterochromaffin-like cells in gastric cancer of cotton rats. APMIS - Journal of Pathologiy, Microbiology and Immunology. volum 113.
Academic article
Stenstrøm, Bjørn; Løseth, Kirsti; Bevanger, Lars Solbu; Sturegård, E; Wadstrøm, T; Chen, Duan. (2005) Gastric bypass surgery does not increase susceptibility to Helicobacter pylori infection in the stomach of rat or mouse. InflammoPharmacology. volum 13.
Academic article

2004

Chen, Duan. (2004) Absence of the cholecystokinin2 receptor alters the structure and function of gastric parietal and ECL cells. Gastrin in the New Millennium.
Academic chapter/article/Conference paper
Chen, Duan. (2004) ECL cells. Encyclopedia of Endocrinology and Endocrine Diseases.
Academic article
Chen, Duan. (2004) ECL cells in a physiological context. Gastrin in the New Millennium.
Academic chapter/article/Conference paper
Rydning, Astrid; Bakkelund, Karin Elvenes; Chen, Duan; Falkmer, Sture Emil; Grønbech, Jon Erik. (2004) Role of bradykinin on gastric vasodilation caused by hypertonic saline and acid back diffusion. Regulatory Peptides.
Academic article
Chen, Duan; Zhao, Chun-Mei; Hakanson, R; Samuelson, LC; Rehfeld, JF; Friis-Hansen, L. (2004) Altered control of gastric acid secretion in gastrin-cholecystokinin double mutant mice. Gastroenterology. volum 126.
Academic article
Cui, GL; Koh, TJ; Chen, Duan; Zhao, Chun-Mei; Takaishi, S; Dockray, GJ; Varro, A; Rogers, AB; Fox, JG; Wang, T. (2004) Overexpression of glycine-extended gastrin inhibits parietal cell loss and atrophy in the mouse stomach. Cancer Research. volum 64.
Academic article

2003

Aihara, T.; Fujishita, T.; Kanatani, K.; Furutani, K.; Nakamura, E.; Taketo, M.M.; Matsui, M.; Chen, Duan; Okabe, S.. (2003) Impaired gastric secretion and lack of trophic responses to hypergastrinemia in M3 muscarinic receptor-knockout mice. Gastroenterology. volum 125.
Academic article
Chen, Duan; Håkanson, R. (2003) Mechanism of gastric ECL-cell tumor induction: Observations in the rat. WHO IARC Technical Publication.
Academic article
Cui, G; Koh, T.; Chen, Duan; Zhao, C.M.; Dockery, J.; Varro, A; Fox, J; Wang, T. (2003) Overexpression of glycine-extended gastrin maintains acid secretion and prevents the development of preneoplasia in the stomach via reducing parietal cell lost in transgenic mice. Gastroenterology. volum 124.
Academic article
Cui, Guanglin; Koh, Theodore J.; Chen, Duan; Zhao, Chun-Mei; Dockray, G.J.; Varro, A.M.; Fox, J; Wang, T. (2003) Overexpression of glycine-extended gastrin maintains acid secretion and prevents the development of preneoplasia in the stomach via reducing parietal cell lost in transgenic mice. Gastroenterology. volum 124.
Feature article
Kopin, Alan S.; McBride, E.W.; Chen, Ci; Chen, Duan; Zhao, Chun-Mei; Beinborn, M. (2003) Identification of a series of CCK-2 receptor nonpeptide agonists: Sensitivity to stereochemistry and a receptor point mutation. PNAS. volum 100 (9).
Academic article
Kopin, Alan S.; McBride, E.W.; Ren, Y.; Chen, Duan; Zhao, C.M.. (2003) Identification of a series of CCK-2 receptor nonpeptide agonists: sensitivity to stereochemistry and a receptor point mutation. Proceedings of the National Academy of Sciences of the United States of America. volum 100.
Academic article
Martinsen, Tom Christian; Bakke, I; Chen, Duan; Aamo, T; Zahlsen, Kolbjørn; Waldum, Helge. (2003) Ciprofibrate stimulates the gastrin-producing cell by acting luminally on antral PPARa receptors. Gastroenterology. volum 124.
Academic article
Waldum, C.; Zhao, C.M.; Waldum, Helge; Halgunset, Jostein; Chen, Duan. (2003) Cheese-induced body weight is not accompained by an increase of gastric cells producing leptin, ghrelin, gastrin, or pancreastatin in mice. Scandinavian Journal of Laboratory Animal Science. volum 30.
Academic article
Waldum, Camilla; Zhao, Chun-Mei; Waldum, Helge; Halgunset, Jostein; Chen, Duan. (2003) Cheese-induced body weight gain is not accompanied by an increase of gastric cells producing leptin, gastrin, or pancreastatin in mice. Scandinavian Journal of Laboratory Animal Science. volum 30.
Academic article
Zhao, C-M; Wang, X.; Friis-Hansen, L; Waldum, Helge; Halgunset, Jostein; Wadstrøm, T; Chen, Duan. (2003) Chronic Helicobacter pylori infection results in gastric hypoacidity and hypergastrinemia in wild-type mice but vagally induced hypersecretion in gastroindeficient mice. Regulatory Peptides. volum 115.
Academic article
Zhao, Chun-Mei; Chen, D; Yamada, H.; Dornonville delaCour, C.; Lindström, E.; Persson, L.; Håkanson, R. (2003) Rat stomach ECL cells: mode of activation of histidine decarboxylase. Regulatory Peptides. volum 114 (1).
Academic article
Zhao, Chun-Mei; Chen, D; Yamada, H.; Dornonville delaCour, C.; Lindström, E.; Persson, L.; Håkanson, R. (2003) Rat stomach ECL cells: mode of activation of histidine decarboxylase. Regulatory Peptides. volum 114 (1).
Academic article
Zhao, Chun-Mei; Chen, Duan; Håkanson, Rolf. (2003) Rat stomach ECL cells: mode of activation of histidine decaroxylase. Regulatory Peptides. volum 114.
Academic article
Zhao, Chun-Mei; Wang, X; Friis-Hansen, L; Waldum, Helge; Halgunset, Jostein; Wadstrøm, T; Chen, Duan. (2003) Chronic Helicobacter pylori infection results in gastric hypoacidity and hypergastrinemia in wild-type mice but vagally induced hypersecretion in gastrin-deficient mice. Regulatory Peptides. volum 115.
Academic article

2002

Chen, Duan; Håkanson, Rolf; Rehfeld, Jens F.; Zhao, Chun-Mei. (2002) CCK2 receptors are necessary for the differentiation and proliferation of ECL cells in mouse and rat stomach. Immunopharmacology. volum 10.
Academic article
Chen, Duan; Wallengren, Joanna. (2002) Local skin lesions in the rat after subcutaneous deposition of Capsaicin. Skin pharmacology and applied skin physiology. volum 15.
Academic article
Chen, Duan; Zhao, Chun-Mei; Håkanson, Rolf; Rehfeld, Jens F.. (2002) Gastric Phenotypic Abnormality in Cholecystokinin 2 Receptor Null Mice. Pharmacology and Toxicology. volum 91.
Academic article
Chen, Duan; Zhao, Chun-Mei; Wisam, Al-Haider; Håkanson, Rolf; Rehfeld, Jens F.; Kopin, Alan S.. (2002) Differentiation of Gastric ECL Cells is Altered in CCK2 Receptor-Deficient Mice. Gastroenterology. volum 123.
Academic article
Farrell, James J.; Taupin, Douglas; Koh, Theodore J.; Chen, Duan; Zhao, Chun-Mei; Podolsky, Daniel K.; Wang, Timothy C.. (2002) TFF2/SP-deficient mice show decreased gastric proliferation, increased acid secretion, and increased susceptibility to NSAID injury. The Journal of Clinical Investigation. volum 102 (2).
Academic article
Lehto-Axtelius, D.; Chen, Duan; Surve, V.V.; Håkanson, Rolf. (2002) Post-Gatrectomy Osteopenia in the Rat. Scandinavian Journal of Gastroenterology. volum 37.
Academic article

2001

Björkqvist, Maria; Norlén, Per; Kitano, Masayuki; Chen, Duan; Zhao, Chun-Mei; Dornonville delaCour, D; Gagnemo-Persson, Rebecca; Håkanson, Rolf. (2001) Effects of CCK-2 receptor blockade on growth parameters in gastrointestinal tract and pancreas in rats. Pharmacology and Toxicology. volum 89.
Academic article
Chen, Duan; Zhao, Chun-Mei; Falkmer, Sture Emil; Waldum, Helge; Syder, Andrew; Gordon, Jeffrey. (2001) Ablation of Parietal Cells Is Associated with ECL-cell Hyperplasia in Transgenic Mice with a Genetically Engineered Ablation of Their Parietal Cell Lineage. Gastroenterology. volum 120 (5).
Academic article
Cui, G.-L.; Syversen, Unni; Chao, Chun-Mei; Chen, Duan; Waldum, Helge. (2001) Long-term Omeprazole treatment Suppresses Body Weight Gain and Bone Mineralization in Young Male Rats. Scandinavian Journal of Gastroenterology. volum 10.
Academic article
Cui, Guanglin; Syversen, Unni; Zhao, Chun-Mei; Chen, Duan; Waldum, Helge. (2001) Long-term omeprazole treatment suppress body weight gain and bone mineralization in young male rats. Scandinavian Journal of Gastroenterology. volum 36.
Academic article
Dornonville delaCour, D; Björkqvist, Maria; Sandvik, Arne Kristian; Håkanson, Rolf; Chen, D. (2001) A-like cells in the rat stomach contain ghrelin and do not operate under gastrin control. Regulatory Peptides. volum 99.
Academic article
Håkanson, Rolf; Chen, Duan; Lindström, Erik; Bernsand, Maria; Norlén, Per. (2001) Control of secretion from rat stomach ECL cells in situ and in primary culture. Scandinavian Journal of Clinical and Laboratory Investigation. volum 61.
Academic article
Lindström, Erik; Chen, Duan; Norlén, Per; Andersson, Kjell; Håkanson, Rolf. (2001) Control of gastric acid secretion: the gastrin-ECL cell - parietal cell axis. Comparative Biochemistry and Physiology A. volum 128.
Academic article
Nieuwenhove, Yves van; Chen, Duan; Willems, Gerard. (2001) Postprandial cell proliferation in the esophageal epithelium of rats. Regulatory Peptides. volum 97.
Academic article
Waldum, Camilla; Zhao, Chun-Mei; Chen, Duan. (2001) Are current textbooks good enough for physiology education? For example, the ECL-cells are missing. Advances in Physiology Education. volum 25.
Academic article
Zhao, Chun-Mei; Bakke, Ingunn; Skogaker, Nan Elisabeth Tostrup; Waldum, Helge; Håkanson, Rolf; Chen, Duan. (2001) Functionally impaired, hypertrophic ECL cells accumulate vacuoles and lipofuscin bodies. An ultrastructural study of ECL cells isolated from hypergastrinemic rats. Cell and Tissue Research.
Academic article
Zhao, Chun-Mei; Bakke, Ingunn; Tostrup-Skogaker, Nan; Waldum, Helge; Håkanson, Rolf; Chen, Duan. (2001) Functionally impaired, hypertrophic ECL cells accumulate vacuoles and lipofuscin bodies. An ultrastructural study of ECL cells isolated from hypergastrinemic rats. Cell and Tissue Research. volum 303.
Academic article

2000

Chen, D; Zhao, CM; Norlen, P; Björkqvist, M; Ding, XQ; Kitano, M; Hakanson, R. (2000) Effect of cholecystokinin-2 receptor blockade on rat stomach ECL cells. A histochemical, electron-microscopic and chemical study. Cell and Tissue Research.
Academic article
Chen, Duan; Zhao, Chun-Mei; Dockray, Graham J.; Varro, Andrea; van Hoek, Alfred; Sinclair, Natalie F.; Wang, Timothy C.. (2000) Glycine-Extended Gastrin Synergizes With Gastrin 17 to Stimulate Acid Secretion in Gastrin-Deficient Mice. Gastroenterology. volum 119.
Academic article
Chen, Duan; Zhao, CM; Dockray, GJ; Varro, A; Hoek, AV; Sinclair, NF; Wang, TC; Koh, TJ. (2000) Glycine-Extended Gastrin Synergizes With Gastrin 17 to Stimulate Acid Secretion in Gastrin-Deficient Mice. Gastroenterology.
Academic article
Norlen, P.; Lindstrøm, E.; Zhao, Chun-Mei; Kitano, M.; Chen, Duan; Andersson, K.; Håkansson, R.. (2000) alpha-fluoromethylhistidine depletes histamine from secreting but not from non-secreting rat stomach ECL-cells. European Journal of Clinical Pharmacology. volum 14 (400).
Academic article
Norlèn, P; Lindström, E; Zhao, CM; Kitano, M; Chen, D; Andersson, K; Håkanson, R. (2000) x-Fluromethylhistidine depletes histamine from secreting but not from non-secreting rat stomach ECL cells. European Journal of Pharmacology: Environmental Toxicology and Pharmacology.
Academic article
Syversen, Unni; Waldum, HL; Slørdahl, K; Chen, D. (2000) Synergistic effects of the pesticides toxaphene and dieldrin on bone mineral density in female rats. Journal of Bone and Mineral Research. volum 15.
Academic article
Wang, TC; Dangler, CA; Chen, D; Goldenring, JR; Koh, T; Raychowdhury, R; Coffey, RJ; Ito, S; Varro, A; Dockray, GJ; Fox, JG. (2000) Synergistic Interaction Between Hypergastrinemia and Helicobacter Infection in a Mouse Model of Gastric Cancer. Gastroenterology.
Academic article

Journal publications

Chen, Duan; Hagen, Susan J; Boyce, Malcolm; Zhao, Chun Mei. (2023) Neuroendocrine mechanism of gastric acid secretion: Historical perspectives and recent developments in physiology and pharmacology. Journal of neuroendocrinology.
Academic article
Chen, Duan; Rehfeld, Jens Frederik; Watts, Alan G; Rorsman, Patrik; Gundlach, Andrew L.. (2023) History of key regulatory peptide systems and perspectives for future research. Journal of neuroendocrinology.
Academic article
Brizozowski, Thomas; Sikiric, Predrag; Chen, Duan; Hahm, Ki-Baik; Seiwerth, Sven. (2022) Editorial: Protection and healing in the digestive system and other tissues: Novel factors, mechanisms, and pharmaceutical targets. Frontiers in Pharmacology. volum 13 (1116643).
Academic article
Rabben, Hanne-Line; Andersen, Gøran Troseth; Ianevski, Aleksandr; Olsen, Magnus Kringstad; Kainov, Denis; Grønbech, Jon Erik; Wang, Timothy Cragin; Chen, Duan; Zhao, Chun-Mei. (2021) Computational Drug Repositioning and Experimental Validation of Ivermectin in Treatment of Gastric Cancer. Frontiers in Pharmacology. volum 12.
Academic article
Rabben, Hanne-Line; Andersen, Gøran Troseth; Olsen, Magnus Kringstad; Øverby, Anders; Ianevski, Aleksandr; Kainov, Denis; Wang, Timothy Cragin; Lundgren, Steinar; Grønbech, Jon Erik; Chen, Duan; Zhao, Chun-Mei. (2021) Neural signaling modulates metabolism of gastric cancer. iScience. volum 24 (2).
Academic article
Rabben, Hanne-Line; Kodama, Yosuke; Nakamura, Masahiko; Bones, Atle M.; Wang, Timothy Cragin; Chen, Duan; Zhao, Chun-Mei; Øverby, Anders. (2021) Chemopreventive Effects of Dietary Isothiocyanates in Animal Models of Gastric Cancer and Synergistic Anticancer Effects With Cisplatin in Human Gastric Cancer Cells. Frontiers in Pharmacology. volum 12.
Academic article
Eiden, Lee E.; Gundlach, Andrew L.; Grinevich, Valery; Lee, Mary R.; Mecawi, André S.; Chen, Duan; Buijs, Ruud M.; Hernández, Vito S.; Fajardo-Dolci, Germán; Zhang, Li-Mei. (2020) Regulatory peptides and systems biology: A new era of translational and reverse-translational neuroendocrinology. Journal of neuroendocrinology. volum 00:e12844.
Academic literature review
Sheng, Weiwei; Ermanno, Malagola,; Henrik, Nienhüser; Zhengyu, Zhang; Woosook, Kim; Leah, Zamechek; Antonia, Sepulveda; Masahiro, Hata; Yoku, Hayakawa; Zhao, Chun-Mei; Chen, Duan; Timothy C., Wang. (2020) Hypergastrinemia Expands Gastric ECL Cells Through CCK2R Progenitor Cells via ERK Activation. Cellular and Molecular Gastroenterology and Hepatology (CMGH). volum 10 (2).
Academic article
Guida, Claudia; Stephen, Sam D.; Watson, Michael; Dempster, Niall; Larraufie, Pierre; Marjot, Thomas; Cargill, Tamsin; Rickers, Lisa; Pavlides, Michael; Tomlinson, Jeremy; Cobbold, Jeremy F.L.; Zhao, Chun-Mei; Chen, Duan; Gribble, Fiona M; Reimann, Frank; Gillies, Richard; Sgromo, Bruno; Rorsman, Patrik; Ryan, John D. (2019) PYY plays a key role in the resolution of diabetes following bariatric surgery in humans. EBioMedicine. volum 40.
Academic article
Chen, Duan; Ayala, Gustavo E. (2018) Innervating Prostate Cancer. New England Journal of Medicine. volum 378 (7).
Academic article
Guida, Claudia; McCulloch, Laura J.; Godazgar, Mahdieh; Stephen, Sam D.; Baker, Charlotte; Basco, Davide; Dong, Jiawen; Chen, Duan; Clark, Anne; Ramracheya, Reshma D.. (2018) Sitagliptin and Roux-en-Y gastric bypass modulate insulin secretion via regulation of intra-islet PYY. Diabetes, obesity and metabolism. volum 20 (3).
Academic article
Olsen, Magnus Kringstad; Johannessen, Helene; Ramracheya, Reshma; Zhao, Chun-Mei; Chen, Duan. (2018) New approaches for weight loss: Experiments using animal models. Current pharmaceutical design. volum 24 (18).
Academic literature review
Zhao, Chun-Mei; Rabben, Hanne-Line; Zhu, Yanping; Olsen, Magnus Kringstad; Wang, Zhiqiang; Hao, Yanpeng; Cai, Xing; Fonseca, Davi de Miranda; Sharma, Animesh; Li, Mingna; Zhihong, Zhang; Slupphaug, Geir; Wang, Timothy Cragin; Chen, Duan. (2018) 390 - A New Treatment for Pancreatic Cancer: Targeting Nervecancer Cell Crosstalk. Gastroenterology. volum 154.
Abstract
Hayakawa, Yoku; Sakitani, Kosuke; Konishi, Mitsuru; Asfaha, Samuel; Niikura, Ryota; Tomita, Hiroyuki; Renz, Bernhard W.; Tailor, Yagnesh; Macchini, Marina; Middelhoff, Moritz; Jiang, Zhengyu; Tanaka, Takayuki; Dubeykovskaya, Zinaida A.; Kim, Woosook; Chen, Xiaowei; Urbanska, Aleksandra M.; Nagar, Karan; Westphalen, Christoph B.; Quante, Michael. (2017) Nerve growth factor promotes gastric tumorigenesis through aberrant cholinergic signaling. Cancer Cell. volum 31 (1).
Academic article
Olsen, Magnus Kringstad; Choi, Man Hung; Kulseng, Bård Eirik; Zhao, Chun-Mei; Chen, Duan. (2017) Time-restricted feeding on weekdays restricts weight gain: A study using rat models of high-fat diet-induced obesity. Physiology and Behavior. volum 173.
Academic article
Johannessen, Helene; Revesz, David; Kodama, Yosuke; Cassie, Nikki; Skibicka, Karolina P.; Barrett, Perry; Dickson, Suzanne; Holst, Jens; Rehfeld, Jens; van der Plasse, Geoffrey; Adan, Roger; Kulseng, Bård Eirik; Ben-Menachem, Elinor; Zhao, Chun Mei; Chen, Duan. (2016) Vagal blocking for obesity control: a possible mechanism-of-action. Obesity Surgery. volum 27 (1).
Academic article
Cai, Xing; Rabben, Hanne-Line; Andersen, Gøran Troseth; Olsen, Magnus Kringstad; Øverby, Anders; Lundgren, Steinar; Grønbech, Jon Erik; Wang, Timothy C.; Chen, Duan; Zhao, Chun-Mei. (2016) A Potential New Regimen (“Tricyclie”) for Treatment of Gastric Cancer: Targeting Glutamine-Dependent Wnt/β-Catenin-mTOR Signaling. Gastroenterology. volum 150 (4).
Abstract
Chen, Duan; Olsen, Magnus Kringstad; Strømmen, Magnus; Johannessen, Helene; Bjøru, Hege Tevik; Salater, Sissel; Johnsen, Gjermund; Mårvik, Ronald; Zhao, Chun-Mei; Kulseng, Bård Eirik. (2016) Intragastric Injection of Botulinum Toxin a to Treat Obesity: Mechanism of Action and a Randomized, Double-Blind, Placebo-Controlled Phase II Trial With Open-Label Extension Study. Gastroenterology. volum 150 (4).
Abstract
Dubeykovskaya, Z; Si, Y; Chen, X; Worthley, DL; Renz, BW; Urbanska, AM; Hayakawa, Y; Xu, T; Westphalen, CB; Dubeykovskiy, A; Chen, Duan; Friedman, RA; Asfaha, S; Nagar, S; Tailor, Y; Muthupalani, S; Fox, JG; Kitajewski, J; Wang, Timothy C.. (2016) Neural innervation stimulates splenic TFF2 to arrest myeloid cell expansion and cancer. Nature Communications. volum 7 (10517).
Academic article
Johannesen, Helene; Revesz, David; Kodama, Yosuke; Cassie, Nikki; Skibicka, Karolina P.; Barrett, Perry; Dickson, Suzanne; Holst, Jens; Rehfeld, Jens F.; van der Plasse, Geoffrey; Adan, Roger; Kulseng, Bård Eirik; Ben-Menachem, Elinor; Zhao, Chun-Mei; Chen, Duan. (2016) Erratum to: Vagal Blocking for Obesity Control: a Possible Mechanism-Of-Action (OBES SURG, 10.1007/s11695-016-2278-x). Obesity Surgery. volum 27 (1).
Errata
Olsen, Magnus Kringstad; Johannessen, Helene; Cassie, Nikki; Barrett, Perry; Takeuchi, Koji; Kulseng, Bård Eirik; Chen, Duan; Zhao, Chun-Mei. (2016) Steady-state energy balance in animal models of obesity and weight loss. Scandinavian Journal of Gastroenterology. volum 52 (4).
Academic article
Rabben, Hanne-Line; Zhao, Chun-Mei; Hayakawa, Yoku; Wang, Timothy C.; Chen, Duan. (2016) Vagotomy and gastric tumorigenesis. Current Neuropharmacology. volum 14 (8).
Academic literature review
Ramracheya, Reshma D.; McCulloch, Laura J.; Clark, Anne; Wiggins, David; Johannessen, Helene; Olsen, Magnus Kringstad; Cai, Xing; Zhao, Chun-Mei; Chen, Duan; Rorsman, Patrik. (2016) PYY-Dependent Restoration of Impaired Insulin and Glucagon Secretion in Type 2 Diabetes following Roux-En-Y Gastric Bypass Surgery. Cell reports. volum 15 (5).
Academic article
Ramracheya, Reshma; McCulloch, Laura J.; Clark, Anne; Olsen, Magnus Kringstad; Zhao, Chun-Mei; Chen, Duan; Rorsman, Patrik. (2016) Roux-En-Y Gastric Bypass Surgery Restores Impaired Islet Architecture and Function in Type-2 Diabetes by Elevation of Plasma PYY. Gastroenterology. volum 150 (4).
Abstract
Øverby, Anders; Rabben, Hanne-Line; Takahashi, Tetsufumi; Zhao, Chun Mei; Matsui, Hidenori; Nakamura, Masahiko; Chen, Duan. (2016) Possible mechanism-of-action of naturally occurring isothiocyanates in chemoprevention and adjuvant chemotherapy for gastric cancer. Gastroenterology.
Abstract
Andersen, Gøran Troseth; Kodama, Yosuke; Hayakawa, Yoku; Vettukattil, Riyas; Grønbech, Jon Erik; Chen, Duan; Zhao, Chun-Mei. (2015) 565Glutamine Metabolism As a Therapeutic Target for Gastric Cancer: Effects of Vagotomy Gastroenterology,Volume 148, Issue 4, Supplement 1, April 2015, Pages S-565–S-566. Gastroenterology. volum 148 (4).
Abstract
Boyce, Malcolm; Dowen, Sally; Turnbull, Gillian; van den Berg, Frans; Zhao, Chun-Mei; Chen, Duan; Black, James. (2015) Effect of netazepide, a gastrin/CCK2 receptor antagonist, on gastric acid secretion and rabeprazole-induced hypergastrinaemia in healthy subjectshypergastrinaemia in healthy subjects. British Journal of Clinical Pharmacology. volum 79 (5).
Academic article
Hayakawa, Yoku; Asfaha, Samuel; Renz, Bernhard W.; Westphalen, Christoph B.; Tailor,, Yagnesh H.; Nagar,, Karan K.; Worthley, Daniel L.; Chen, Duan; Wang, Timothy C.. (2015) NGF Promotes Gastrointestinal Cancer Development Through Tumor-Associated Neurogenesis. Gastroenterology. volum 148 (4).
Abstract
Hayakawa, Yoku; Jin, Guangchun; Wang, Hongshan; Chen, Xiaowei; Westphalen, Christoph B.; Asfaha, Samuel; Renz, Bernhard W.; Ariyama, Hiroshi; Dubeykovskaya, Zinaida A.; Takemoto, Yoshihiro; Lee, Yoomi; Muley, Ashlesha; Tailor, Yagnesh H.; Chen, Duan; Muthupalani, Sureshkumar; Fox, James G.; Shulkes, Arthur; Worthley, Daniel L.; Takaishi, Shigeo. (2015) CCK2R identifies and regulates gastric antral stem cell states and carcinogenesis. Gut. volum 64 (4).
Academic article
Olsen, Magnus Kringstad; Johannessen, Helene; Kodama, Yosuke; Kulseng, Bård Eirik; Zhao, Chun-Mei; Chen, Duan. (2015) Comparison of different surgical procedures in animal models for a better consideration of personalized bariatric surgery. Gastroenterology. volum 148 (4).
Abstract
Chen, Duan. (2014) Skal teste Botox i kampen mot kreft. Sunnmørsposten.
publications.INTERVJUSKRIFTL
Dragsted, Lars Ove; Alexander, Jan; Amdam, Gro Vang; Bryan, Nathan S.; Chen, Duan; Haug, Anna; Karlsson, Anders H.; de Kok, Theo M.; Kulseng, Bård Eirik; Martin Jr, Roy J.; Milkowski, Andrew L.; Pajari, Anne-Maria; Pickova, Jana; Rudi, Knut; Sødring, Marianne Sundt; Oostindjer, Marije; Egelandsdal, Bjørg. (2014) Letter to the Editor: Colorectal cancer risk and association with red meat - Is it inconsistent? Answer to the letter by Corpet, De Smet and Demeyer. Meat Science. volum 98 (4).
Letter to the editor
Gudbrandsen, Oddrun Anita; Kodama, Yosuke; Mjøs, Svein Are; Zhao, Chun-Mei; Johannesen, Helene; Brattbakk, Hans-Richard; Haugen, Christine; Kulseng, Bård Eirik; Mellgren, Gunnar; Chen, Duan. (2014) Effects of duodenal switch alone or in combination with sleeve gastrectomy on body weight and lipid metabolism in rats. Nutrition and Diabetes. volum 4 (JUNE).
Academic article
Johannessen, Helene; Olsen, Magnus Kringstad; Cassie, Nikki; Barrett, Perry; Rehfeld, Jens F.; Holst, Jens J.; Kulseng, Bård Eirik; Zhao, Chun-Mei; Chen, Duan. (2014) Preclinical Trial of Gastric Injection of Botulinum Toxin Type A as Weight-Loss-Surgery. Gastroenterology. volum 146 (5).
Abstract
Okabe, Susumu; Okamoto, Toshihiro; Zhao, Chun-Mei; Chen, Duan; Matsui, Hirofumi. (2014) Acetic acid induces cell death: An in vitro study using normal rat gastric mucosal cell line and rat and human gastric cancer and mesothelioma cell lines. Journal of Gastroenterology and Hepatology. volum 29 (S4).
Academic article
Oostindjer, Marije; Alexander, Jan; Amdam, Gro Vang; Andersen, Grethe; Bryan, Nathan S.; Chen, Duan; Corpet, Denis E.; De Smet, Stefaan; Dragsted, Lars Ove; Haug, Anna; Karlsson, Anders H.; Kleter, Gijs; de Kok, Theo M.; Kulseng, Bård Eirik; Milkowski, Andrew L.; Martin, Roy; Pajari, Anne-Maria; Paulsen, Jan Erik; Pickova, Jana. (2014) The role of red and processed meat in colorectal cancer development: a perspective. Meat Science. volum 97 (4).
Academic literature review
Zhao, Chun-Mei; Hayakawa, Yoku; Kodama, Yosuke; Muthupalani, Sureshkumar; Westphalen,, Christoph B.; Andersen, Gøran Troseth; Flatberg, Arnar; Johannessen, Helene; Friedman, Richard A.; Renz, Bernhard W.; Sandvik, Arne Kristian; Beisvag, Vidar; Tomita, Hiroyuki; Hara, Akira; Quante, Michael; Li, Zhishan; Gershon, Michael D.; Kaneko, Kazuhiro; Fox,, James G.. (2014) Denervation suppresses gastric tumorigenesis. Science Translational Medicine. volum 6 (250).
Academic article
Zhao, Chun-Mei; Kodama, Yosuke; Flatberg, Arnar; Beisvag, Vidar; Kulseng, Bård Eirik; Sandvik, Arne Kristian; Rehfeld, Jens F.; Chen, Duan. (2014) Gene expression profiling of gastric mucosa in mice lacking CCK and gastrin receptors. Regulatory Peptides. volum 192-193.
Academic article
Zhao, Chun-Mei; Mark, Kidd,; Chen, Duan. (2014) Triple Roles of Autophagy in Cytoprotection, Cell Death and Tumorigenesis With Special Reference to Gastric ECL Cells. Gastroenterology. volum 146 (5).
Abstract
Zhao, Chun-Mei; Myrvold, Helge Elliot; Chen, Duan. (2014) Reduced neurons in the ileum of proctocolectomized rat models. Medical Molecular Morphology. volum 48 (3).
Academic article
Zhao, Chun-Mei; Yoku, Hayakawa; Westphalen,, Christoph B; Muthupalani,, Sureshkumar; Johannessen, Helene; Andersen, Gøran Troseth; Fox,, James G; Wang,, Timothy C.; Chen, Duan. (2014) Preclinical Trial of Botulinum Toxin Type a Injection in the Treatment of Gastric Cancer. Gastroenterology. volum 146 (5).
Abstract
Øverby, Anders; Zhao, Chun-Mei; Bones, Atle M.; Chen, Duan. (2014) Naturally occurring phenethyl isothiocyanate-induced inhibition of gastric cancer cell growth by disruption of microtubules. Journal of Gastroenterology and Hepatology. volum 29 (4).
Academic article
Øverby, Anders; Zhao, Chun-Mei; Chen, Duan. (2014) Plant phytochemicals: Potential anticancer agents against gastric cancer. Current opinion in pharmacology (Print). volum 19.
Academic article
Øverby, Anders; Zhao, Chun-Mei; Wang, Timothy C.; Bones, Atle M.; Chen, Duan. (2014) Gastric cancer chemoprevention by phenethyl isothiocyanate-containing diet in chemically - but not genetically - induced gastric cancer in mice. Gastroenterology. volum 146.
Abstract
Johannessen, Helene; Revesz, David; Kodama, Yosuke; Cassie, Nikki; Skibicka, Karolina P.; Lyle, Robert; Bettencourt, Paulo; Miroljub, Popovic; Witter, Menno; Barrett, Perry; Dickson, Suzanne L.; Koji, Takeuchi; Kulseng, Bård; Thorlin, Thorleif; Ben-Menachem, Elinor; Zhao, Chun-Mei; Chen, Duan. (2013) Role of the vagus nerve in the gut-brain axis revealed by stimulation and blockade of the gastric vagus nerve. Gastroenterology. volum 144 (5).
Abstract
Kodama, Yosuke; Johannessen, Helene; Furnes, Marianne Waldum; Zhao, Chun-Mei; Johnsen, Gjermund; Mårvik, Ronald; Kulseng, Bård; Chen, Duan. (2013) Mechanistic Comparison between Gastric Bypass vs. Duodenal Switch with Sleeve Gastrectomy in Rat Models. PLOS ONE. volum 8 (9).
Academic article
Kodama, Yosuke; Zhao, Chun-Mei; Muthupalani, Sureshkumar; Flatberg, Arnar; Friedman, Richard A.; Sandvik, Arne; Beisvag, Vidar; Johannessen, Helene; Hayakawa, Yoku; Tomita, Hiroyuki; Hara, Akira; Westphalen, Christoph B.; Quante, Michael; Kaneko, Kazuhiro; Fox, James G.; Wang, Timothy C.; Chen, Duan. (2013) Denervation Suppresses Gastric Cancer Initiation and Progression Through Inhibition of the Cancer Niche. Gastroenterology. volum 144 (5).
Abstract
Chen, Duan; Zhao, Chun-Mei. (2013) Signaling pathways in control of gastric acid secretion and food-stomach-bone axis revealed by gene expression profiling in the stomach of genetically targeted mice deficient in CCK1 receptor and gastrin/CCK2 receptor. The FASEB Journal. volum 27:1093.25.
Abstract
Johannessen, Helene; Kodama, Yosuke; Zhao, Chun-Mei; Sousa, Mirta; Slupphaug, Geir; Kulseng, Bård Eirik; Chen, Duan. (2013) Eating Behavior and Glucagon-Like Peptide-1-Producing Cells in Interposed Ileum and Pancreatic Islets in Rats Subjected to Ileal Interposition Associated with Sleeve Gastrectomy. Obesity Surgery. volum 23 (1).
Academic article
Vigen, Alexander; Kodama, Yosuke; Viset, Trond; Fossmark, Reidar; Waldum, Helge; Kidd, Mark; Wang, Timothy C.; Modlin, Irvin; Chen, Duan; Zhao, Chun-Mei. (2013) Immunohistochemical evidence for an impairment of autophagy in tumorigenesis of gastric carcinoids and adenocarcinomas in rodent models and patients. Histology and Histopathology. volum 28 (4).
Academic article
Okabe, Susumu; Kodama, Yosuke; Cao, HaiLong; Johannessen, Helene; Zhao, Chun-Mei; Wang, TC; Takahashi, Rei; Chen, Duan. (2012) Topical application of acetic acid in cytoreduction of gastric cancer model in mice. A technical report. Journal of Gastroenterology and Hepatology. volum 27 (s3).
Academic article
Chen, Duan; Zhao, Chun-Mei. (2012) Importance of Translational Research in GI Pharmacology: Lessons Learned from the Successes in History. Frontiers of gastrointestinal research. volum 30.
Academic article
Erlandsen, Sten Even; Qvigstad, Gunnar; Fossmark, Reidar; Bakke, Ingunn; Chen, Duan; Sandvik, Arne Kristian. (2012) Regulated endocrine-specific protein 18 (RESP18) is localized to and regulated in A-like cells and G-cells in rat stomach. Regulatory Peptides. volum 177 (1-3).
Academic article
Johannessen, Helene; Kodama, Yosuke; Zhao, Chun-Mei; Johnsen, Gjermund; Mårvik, Ronald; Kulseng, Bård Eirik; Chen, Duan. (2012) Evidence for the Hindgut Hypothesis After Ileal Interposition Associated With Sleeve Gastrectomy: Increased Number of GLP-1-Producing Cells in Interposed Ileum and Pancreatic Islets in Rats. Gastroenterology. volum 142 (5).
Abstract
Johannessen, Helene; Kodama, Yosuke; Zhao, Chun-Mei; Johnsen, Gjermund; Mårvik, Ronald; Kulseng, Bård Eirik; Chen, Duan; Revesz, David; Kuhn, Georg; Thorlin, Thorleif; Ben-Menachem, Elinor. (2012) Altered Eating Behavior by Subdiaphragmatic Truncal Vagus Nerve Stimulation in Rats. Gastroenterology. volum 142 (5).
Abstract
Kodama, Yosuke; Flatberg, Arnar; Anderssen, Endre; Sandvik, Arne Kristian; Chen, Duan; Zhao, Chun-Mei. (2012) Food Intake Associated Gene Expression Profiles in the Stomach of Genetically Targeted Mice Deficient in CCK1 Receptor and/or CCK2 Receptor. Gastroenterology. volum 142 (5).
Abstract
Kodama, Yosuke; Johannessen, Helene; Furnes, Marianne Waldum; Zhao, Chun-Mei; Johnsen, Gjermund; Mårvik, Ronald; Kulseng, Bård Eirik; Chen, Duan. (2012) Gastric Bypass and Duodenal Switch Cause Body Weight Loss Through Different Mechanisms in Rats. Gastroenterology. volum 142 (5).
Abstract
Kodama, Yosuke; Zhao, Chun-Mei; Quante, Michael; Muthupalani, Sureshkumar; Flatberg, Arnar; Friedman, Richard A.; Sandvik, Arne Kristian; Fox, James G.; Kaneko, Kazuhiro; Wang, Timothy C.; Chen, Duan. (2012) Vagotomy Suppresses Gastric Cancer Progression in Mice. Gastroenterology. volum 142 (5).
Abstract
Liu, Yanhua; Zhu, Lijun; Pan, Ya; Sun, Lizhou; Chen, Duan; Li, Xiaonan. (2012) Adiponectin Levels in Circulation and Breast Milk and mRNA Expression in Adipose Tissue of Preeclampsia Women. Hypertension in Pregnancy. volum 31 (1).
Academic article
Vigen, Alexander; Chen, Duan; Zhao, Chun-Mei. (2012) Pathobiology of Gastric Carcinoids and Adenocarcinomas in Rodent Models and Patients: Studies of Gastrocystoplasty, Gender-Related Factors and Autophagy. Frontiers of gastrointestinal research. volum 30.
Academic article
Vigen, Alexander; Kidd, Mark; Modlin, IM; Chen, Duan; Zhao, Chun-Mei. (2012) Ultrastructure of ECL cells in Mastomys after long-term treatment with H-2 receptor antagonist loxtidine. Medical Molecular Morphology. volum 45 (2).
Academic article
Vigen, Alexander; Kodama, Yosuke; Viset, Trond; Fossmark, Reidar; Waldum, Helge; Kidd, Mark; Wang, Timothy C.; Modlin, Irvin; Chen, Duan; Zhao, Chun-Mei. (2012) Impaired Autophagy in Gastric Carcinoids and Adenocarcinoma of Both Rodent Models and Patients. Gastroenterology. volum 142 (5).
Abstract
Vigen, Reidar Alexander; Arum, Carl-Jørgen; Viset, Trond; Chen, Duan; Zhao, Chun-Mei. (2012) Experimental gastrocystoplasty in rats: Risk of developing ECLoma. Journal of Pediatric Urology. volum 8 (2).
Academic article
Zhao, Chun-Mei; Chen, Duan. (2012) The ECL Cell: Relay Station for Gastric Integrity. Current Medicinal Chemistry. volum 19 (1).
Academic literature review
Johannessen, Helene; Kodama, Yosuke; Cao, HaiLong; Kulseng, Baard; Zhao, Chun-Mei; Chen, Duan. (2011) Eating Behavior in Rats Subjected to Ileum Transposition and Sleeve Gastrectomy. Gastroenterology. volum 140 (5).
Abstract
Zhao, Chun-Mei; Kodama, Yosuke; Flatberg, Arnar; Sandvik, Arne Kristian; Chen, Duan. (2011) Stomach-Bone Axis: Possible Involvement of Signaling Pathways and Vitamin D Governing Bone Metabolism. Gastroenterology. volum 140 (5).
Abstract
Arum, Carl-Jørgen; Gederaas, Odrun Arna; Larsen, Eivind La Puebla; Randeberg, Lise Lyngsnes; Hjelde, Astrid; Krokan, Hans Einar; Svaasand, Lars O.; Chen, Duan; Zhao, Chun-Mei. (2011) Tissue responses to hexyl 5-aminolevulinate-induced photodynamic treatment in syngeneic orthotopic rat bladder cancer model: possible pathways of action. Journal of Biomedical Optics. volum 16 (2).
Academic article
Cao, HaiLong; Xue, L; Xu, X; Wu, Y; Zhu, J; Chen, L; Chen, Duan; Chen, YJ. (2011) Heat shock proteins in stabilization of spontaneously restored sinus rhythm in permanent atrial fibrillation patients after mitral valve surgery. Cell stress & chaperones (Print). volum 16 (5).
Academic article
Cao, HaiLong; Xue, L; Xu, X; Wu, Y; Zhu, J; Chen, L; Chen, Duan; Chen, YJ. (2011) Heat shock proteins in stabilization of spontaneously restorted sinus rhythm in permanent atrial fibrillation patients after mitral valve surgery. Cell stress & chaperones (Print). volum 16 (5).
Academic article
Chen, D; Truong, T; Gaborieau, V; Byrnes, G; Chabrier, A; Chuang, SC; Olshan, AF; Weissler, MC; Luo, JC; Romkes, M; Buch, S; Nukui, T; Franceschi, S; Herrero, R; Talamini, R; Kelsey, KT; Christensen, B; McClean, MD; Lacko, M. (2011) A Sex-Specific Association between a 15q25 Variant and Upper Aerodigestive Tract Cancers. Cancer Epidemiology, Biomarkers and Prevention. volum 20 (4).
Academic article
Chen, Duan; Zhao, Chun-Mei. (2011) The possible existence of a gut-bone axis suggested by studies of genetically manipulated mouse models?. Current pharmaceutical design. volum 17 (16).
Academic literature review
Cui, Fei; Wang, Jian; Chen, Duan; Chen, Yi-Jiang. (2011) CD133 is a temporary marker of cancer stem cells in small cell lung cancer, but not in non-small cell lung cancer. Oncology Reports. volum 25 (3).
Academic article
Hutchinson, Lloyd; Stenström, Björn; Chen, Duan; Piperdi, Bilal; Levey, Sara; Lyle, Stephen; Wang, Timothy C.; Houghton, J. (2011) Human Barrett's adenocarcinoma of the esophagus, associated myofibroblasts, and endothelium can arise from bone marrow-derived cells after allogeneic stem cell transplant. Stem Cells and Development. volum 20 (1).
Academic article
Kodama, Yosuke; Johannessen, Helene; Furnes, Marianne Waldum; Zhao, Chun-Mei; Kulseng, Bård Eirik; Chen, Duan. (2011) Energy Metabolism Following High-Fat Diet and Bariatric Surgeries (Gastric Bypass, Sleeve Gastrectomy, Duodenal Switch and Ileum Transposition) in Rats. Gastroenterology. volum 140 (5).
Abstract
Kodama, Yosuke; Zhao, Chun-Mei; Quante, Michael; Muthupalani, Sureshkumar; Flatberg, Arnar; Sandvik, Arne Kristian; Fox, James G.; Wang, Timothy C.; Chen, Duan. (2011) Evidence for Mechanism of Vagal Innervation in Gastric Cancer Initiation Involving Signaling Pathways Governing Stem Cells in Mice. Gastroenterology. volum 140 (5).
Abstract
Salome, N; Taube, M; Egecioglu, E; Hansson, C; Karlsson, Bjørn; Chen, Duan; Andersson, DR; Georg-Kuhn, H; Ohlsson, C; Dickson, SL. (2011) Gastrectomy alters emotional reactivity in rats: neurobiological mechanisms. European Journal of Neuroscience. volum 33 (9).
Academic article
Vigen, Reidar Alexander; Chen, Duan; Syversen, Unni; Stunes, Astrid Kamilla; Håkanson, Rolf; Zhao, Chun-Mei. (2011) Serum gastrin and gastric enterochromaffin-like cells during estrous cycle, pregnancy and lactation, and in response to estrogen-like agents in rats. Journal of Physiology and Pharmacology. volum 62 (3).
Academic article
Vigen, Reidar Alexander; Kidd, Mark; Modlin, Irvin; Chen, Duan; Zhao, Chun-Mei. (2011) Ultrastructral Evidence for a Mechanism of ECL Cell Transformation to Gastric Carcinoid in Mastomys Involving Impairment of Autophagy and Loss of Gastrin Control. Gastroenterology. volum 140 (5).
Abstract
Westerberg, I.; Walther, A; Guerrero, J-L; Coello, Z; Halldin, S; Xu, Chong-Yu; Chen, D; Lundin, L-C. (2010) Precipitation data in a mountainous catchment in Honduras: quality assessment and spatiotemporal characteristics. Theoretical and Applied Climatology. volum 101 (3-4).
Academic article
Arum, Carl-Jørgen; Anderssen, Endre; Tømmerås, Karin; Lundgren, Steinar; Chen, Duan; Zhao, Chun-Mei. (2010) Gene Expression Profiling and Pathway Analysis of Superficial Bladder Cancer in Rats. Urology. volum 75 (3).
Academic article
Arum, Carl-Jørgen; Anderssen, Endre; Viset, Trond; Kodama, Yosuke; Lundgren, Steinar; Chen, Duan; Zhao, Chun-Mei. (2010) Cancer Immunoediting from Immunosurveillance to Tumor Escape in Microvillus-Formed Niche: A Study of Syngeneic Orthotopic Rat Bladder Cancer Model in Comparison with Human Bladder Cancer. Neoplasia. volum 12 (6).
Academic article
Arum, Carl-Jørgen; Kodama, Yosuke; Rolim, Natale Pinheiro Lage; Widerøe, Marius; Anderssen, Endre; Viset, Trond; Otterlei, Marit; Lundgren, Steinar; Chen, Duan; Zhao, Chun-Mei. (2010) A rat model of intravesical delivery of small interfering RNA for studying urinary carcinoma. World Journal of Urology. volum 28 (4).
Academic article
Chen, Duan; Zhao, Chun-Mei. (2010) Complexity of Gastric Acid Secretion Revealed by Targeted Gene Disruption in Mice. Current pharmaceutical design. volum 16 (10).
Academic literature review
Kodama, Yosuke; Zhao, Chun-Mei; Kulseng, Baad; Chen, Duan. (2010) Eating Behavior in Rats Subject to Vagotomy, Sleeve Gastrectomy and Duodenal Switch. Gastroenterology. volum 14.
Academic article
Kodama, Yosuke; Zhao, Chun-Mei; Kulseng, Bård Eirik; Chen, Duan. (2010) Eating Behavior in Rats Subjected to Vagotomy, Sleeve Gastrectomy, and Duodenal Switch. Journal of Gastrointestinal Surgery. volum 14 (10).
Academic article
Kodama, Yosuke; Zhao, Chun-Mei; Quante, Michael; Muthupalani, Sureshkumar; Fox, James G.; Wang, Timothy C.; Chen, Duan. (2010) Truncal vagotomy inhibited gastric cancer initiation in the INS-GAS mouse model. Gastroenterology. volum 136.
Abstract
Song, Zhigang; Bhagat, Govind; Quante, Michael; Baik, Gwang Ho; Marrache, Frederic; Tu, Shuiping; Zhao, Chun-Mei; Chen, Duan; Dannenberg, Andrew; Wang, Timothy C.. (2010) Potential carcinogenic effects of cigarette smoke and Swedish moist snuff on pancreas: a study using a transgenic mouse model of chronic pancreatitis. Laboratory Investigation. volum 90 (3).
Academic article
Zhao, Chun-Mei; Kodama, Yosuke; Flatberg, Arnar; Anderssen, Endre; Sandvik, Arne Kristian; Chen, Duan. (2010) Gastric ECL cells, rather than gastric acid, play an important role in gut-bone axis. Gastroenterology. volum 136.
Abstract
Zheng, Liang; Xu, Jing; Qiu, Wanshan; Liu, Xiang; Zhao, Chun-Mei; Chen, Duan; Chen, Yi-Jiang. (2010) CARDIOPROTECTION OF EXOGENOUS ERYTHROPOIETIN IN MICE WITH LIGATURE-INDUCED AORTIC STENOSIS: EFFECTS ON MALADAPTIVE CARDIAC HYPERTROPHY. Journal of Physiology and Pharmacology. volum 61 (1).
Academic article
Arum, Carl-Jørgen; Anderssen, Endre; Tømmerås, Karin; Zhao, Chun-Mei; Chen, Duan. (2009) Gene expression profiles of bladder cancer: Comparison between orthotopic rat bladder cancer model and human bladder cancer patients. European Urology. Supplement. volum 8 (4).
Abstract
Chen, Duan; Furnes, Marianne Waldum; Zhao, Chun-Mei. (2009) Translational research on obesity: from bedside to bench. Journal of Physiology and Pharmacology. volum 60.
Academic article
Furnes, Marianne Waldum; Zhao, Chun-Mei; Chen, Duan. (2009) Development of Obesity is Associated with Increased Calories per Meal Rather than per Day. A Study of High-Fat Diet-Induced Obesity in Young Rats. Obesity Surgery. volum 19 (10).
Academic article
Furnes, Marianne; Zhao, Chun-Mei; Stenstrøm, Bjørn; Arum, Carl-Jørgen; Tømmerås, Karin; Kulseng, Bård Eirik; Chen, Duan. (2009) Feeding behavior and body weight development: Lessons from rats subjected to gastric bypass surgery or high-fat diet. Journal of Physiology and Pharmacology. volum 60.
Academic article
Song, Zhigang; Bhagat, Govind; Baik, Gwang Ho; Gordon, Shanisha A.; Mitchell, Anthony; Zhao, Chun-Mei; Chen, Duan; Dannenberg,, Andrew; Wang, Timothy C.. (2009) Development of a Mouse Model of Inflammation-Dependent Pancreatic Cancer. Gastroenterology. volum 136 (5).
Academic article
Zhao, Chun-Mei; Anderssen, Endre; Chen, Duan. (2009) Gene Expression and Pathway Analysis of Mouse Stomach: Gastric ECL Cells May Produce Vitamin D. Gastroenterology. volum 136 (5).
Academic article
Zhao, Chun-Mei; Kodama, Yosuke; Sandvik, Arne Kristian; Chen, Duan. (2009) Differentiation of Gastric ECL Cells in CCK 1+2 Receptor Double Knockout Mice. Gastroenterology. volum 136 (5).
Academic article
Qiu, Wanshan; Gu, Haiyong; Zheng, Liang; Zhou, Jianwei; Chen, Duan; Chen, Yijiang. (2008) Pretreatment with edaravone reduces lung mitochondrial damage in an infant rabbit ischemia-reperfusion model. Journal of Pediatric Surgery. volum 43 (11).
Academic article
Qiu, Wanshan; Zheng, Liang; Gu, Haiyong; Chen, Duan; Chen, Yijiang. (2008) Comparison between adult and infant lung injury in a rabbit ischemia-reperfusion model. Journal of Thoracic and Cardiovascular Surgery. volum 136 (2).
Academic article
Zhao, Chun-Mei; Furnes, Marianne Waldum; Stenström, Björn; Kulseng, Bård Eirik; Chen, Duan. (2008) Characterization of obestatin- and ghrelin-producing cells in the gastrointestinal tract and pancreas of rats: an immunohistochemical and electron-microscopic study. Cell and Tissue Research. volum 331 (3).
Academic article
Bernsand, Maria; Zhao, Chun-Mei; Chen, Duan; Håkanson, R; Stenstrøm, Bjørn; Norlén, Per. (2008) Ischemia mobilizes histamine but not pancreastatin from ECL cells of rat stomach: evidence for a cytosolic histamine compartment. Cell and Tissue Research. volum 333 (3).
Academic article
Egecioglu, E; Stenstrom, B; Pinnock, SB; Tung, LYC; de la Cour, CD; Lindqvist, A; Hakanson, R; Syversen, Unni; Chen, Duan; Dickson, SL. (2008) Hypothalamic gene expression following ghrelin therapy to gastrectomized rodents. Regulatory Peptides. volum 146.
Academic article
Furnes, Marianne Waldum; Stenstrøm, Bjørn; Tømmerås, Karin; Skoglund, Trine; Dickson, SL; Kulseng, Bård Eirik; Zhao, Chun-Mei; Chen, Duan. (2008) Feeding behaviour in rats subjected to gastrectomy or gastric bypass surgery. European Surgical Research. volum 40 (3).
Academic article
Furnes, Marianne Waldum; Tømmerås, Karin; Arum, Carl-Jørgen; Zhao, Chun-Mei; Chen, Duan. (2008) Gastric bypass surgery causes body weight loss without reducing food intake in rats. Obesity Surgery. volum 18.
Academic article
Larsen, Eivind La Puebla; Randeberg, Lise Lyngsnes; Gederaas, Odrun Arna; Arum, Carl-Jørgen; Hjelde, Astrid; Zhao, Chun-Mei; Chen, Duan; Krokan, Hans Einar; Svaasand, Lars O.. (2008) Monitoring of Hexyl 5-aminolevulinate Induced Photodynamic Therapy in Rat Bladder Cancer by Optical Spectroscopy. Journal of Biomedical Optics. volum 13 (4).
Academic article
Zhao, Chun-Mei; Martinez, V; Piqueras, L; Wang, L-X; Taché, Y; Chen, Duan. (2008) Control of gastric acid secretion in somatostatin receptor 2 deficient mice: shift from endocrine/paracrine to neurocrine pathways. Endocrinology. volum 149 (2).
Academic article
Arum, Carl-Jørgen; Tømmerås, Karin; Anderssen, Endre; Zhao, Chun-Mei; Chen, Duan. (2007) Gene expression profiling and pathway analysis of orthotopic rat bladder cancer model. European Urology. Supplement. volum 6.
Abstract
Chen, Duan; Karlsson, Bjørn; Zhao, Chun-Mei; Wadstrom, T. (2007) Does Helicobacter pylori infection per se cause gastric cancer or duodenal ulcer? Inadequate evidence in Mongolian gerbils and inbred mice. FEMS Immunology and Medical Microbiology. volum 50.
Academic article
Chen, Duan; Zhao, Chun-Mei. (2007) Genetically engineered mice: a new paradigm to study gastric physiology. Current Opinion in Gastroenterology. volum 23.
Academic article
Egecioglu, E; Karlsson, Bjørn; Pinnock, S B; Tung, LYC; Dornonville de la Cour, C; Lindqvist, A; Håkanson, R; Syversen, Unni; Chen, Duan; Dickson, SL. (2007) Hypothalamic gene expression following ghrelin therapy to gastrectomized rodents. Regulatory Peptides. volum 14.
Academic article
Karlsson, Bjørn; Zhao, Chun-Mei; Rogers, AB; Nilsson, HO; Sturegard, E; Lundgren, Steinar; Fox, J; Wang, Timothy C.; Chen, Duan; Wadstrom, T. (2007) Swedish moist snuff accelerates gastric cancer development in Helicobacter pylori-infected wild-type and gastrin transgenic mice. Carcinogenesis. volum 28.
Academic article
Zhao, Chun-Mei; Chen, Duan. (2007) Genetically engineered mice: a new paradigm to study gastric physiology. Stomach and duodenum. Current Opinion in Gastroenterology. volum 23 (6).
Academic article
Chen, Duan; Aihara, Takeshi; Zhao, Chun-Mei; Håkanson, Rolf; Okabe, Susumu. (2006) Differentiation of the Gastric Mucosa I. Role of histamine in control of function and integrity of oxyntic mucosa: understanding gastric physiology through disruption of targeted genes. American Journal of Physiology - Gastrointestinal and Liver Physiology. volum 291.
Academic article
Zhao, Chun-Mei; Chen, Duan; Stenström, Björn. (2006) Does Helicobacter pylori infection per se cause gastric cancer and/or duodenal ulcer in Mongolian gerbils and wild-type mice? A critical micro-review. FEMS Immunology and Medical Microbiology.
Academic article
Fykse, Vidar; Solligård, Erik; Bendheim, Marianne Østensen; Chen, Duan; Grønbech, Jon Erik; Sandvik, Arne Kristian; Waldum, Helge. (2006) ECL cell histamine mobilization and parietal cell stimulation in the rat stomach studied by microdialysis and electron microscopy. Acta Physiologica. volum 186.
Academic article
Larsen, Eivind La Puebla; Randeberg, Lise Lyngsnes; Gederaas, Odrun Arna; Arum, Carl-Jørgen; Krokan, Hans Einar; Chen, Duan; Hjelme, Dag Roar; Svaasand, Lars O.. (2006) Monitoring of hALA induced PDT in rat bladder cancer by optical spectroscopy. Lasers in Surgery and Medicine.
Abstract
Stenstrøm, Bjørn Olof; Zhao, Chun-Mei; Tømmerås, Karin; Arum, Carl-Jørgen; Chen, Duan. (2006) Is gastrin partially responsible for body weight reduction after gastric bypass?. European Surgical Research. volum 38.
Academic article
Stenstrøm, Bjørn; Furnes, Marianne Waldum; Tømmerås, Karin; Syversen, Unni; Zhao, Chun-Mei; Chen, Duan. (2006) Mechanism of gastric bypass-induced body weight loss: One-year follow-up after micro-gastric bypass in rats. Journal of Gastrointestinal Surgery. volum 10 (10).
Academic article
Vigen, RA; Arum, Carl-Jørgen; Karlsson, Bjørn; Chen, Duan. (2006) A unique surgical model for studying the physiology of gastrin: Gastrocystoplasty and fundectomy. Scandinavian Journal of Laboratory Animal Science. volum 33.
Academic article
Arum, Carl-Jørgen; Vigen, RA; Karlsson, Bjørn; Tømmerås, Karin; Zhao, Chun-Mei; Chen, Duan. (2005) Acid secretion in urinary bladder of rats subjected to gastrocystoplasty. InflammoPharmacology. volum 13.
Academic article
Chen, Duan; Friis-Hansen, L; Håkanson, R; Zhao, Chun-Mei. (2005) Genetic dissection of the signaling pathways that control gastric acid secretion. InflammoPharmacology. volum 13.
Academic literature review
Martinsen, Tom Christian; Bakke, Ingunn; Chen, Duan; Sandvik, Arne Kristian; Zahlsen, Kolbjørn; Aamo, T.; Waldum, Helge. (2005) Ciprofibrate stimulates the gastrin-producing cell by acting luminally on antral PPAR-alfa. American Journal of Physiology - Gastrointestinal and Liver Physiology. volum 289.
Academic article
Zhao, Chun-Mei; Fossmark, Reidar; Martinsen, Tom Christian; Kawase, Shiro; Chen, Duan; Waldum, Helge. (2005) Dedifferentiation of enterochromaffin-like cells in gastric cancer of hypergastrinemic cotton rats. APMIS - Journal of Pathologiy, Microbiology and Immunology. volum 113.
Academic article
Zhao, Chun-Mei; Håkanson, Rolf; Chen, Duan. (2005) Secretory organelles in ECL cells: effects of pharmacological blockade of the gastrin/CCK2 receptor versus its elimination by gene targeting. InflammoPharmacology. volum 13.
Academic literature review
Fossmark, Reidar; Zhao, Chun-Mei; Martinsen, Tom Christian; Kawase, Shiro; Chen, Duan; Waldum, Helge. (2005) Dedifferentiation of enterochromaffin-like cells in gastric cancer of cotton rats. APMIS - Journal of Pathologiy, Microbiology and Immunology. volum 113.
Academic article
Stenstrøm, Bjørn; Løseth, Kirsti; Bevanger, Lars Solbu; Sturegård, E; Wadstrøm, T; Chen, Duan. (2005) Gastric bypass surgery does not increase susceptibility to Helicobacter pylori infection in the stomach of rat or mouse. InflammoPharmacology. volum 13.
Academic article
Chen, Duan. (2004) ECL cells. Encyclopedia of Endocrinology and Endocrine Diseases.
Academic article
Rydning, Astrid; Bakkelund, Karin Elvenes; Chen, Duan; Falkmer, Sture Emil; Grønbech, Jon Erik. (2004) Role of bradykinin on gastric vasodilation caused by hypertonic saline and acid back diffusion. Regulatory Peptides.
Academic article
Chen, Duan; Zhao, Chun-Mei; Hakanson, R; Samuelson, LC; Rehfeld, JF; Friis-Hansen, L. (2004) Altered control of gastric acid secretion in gastrin-cholecystokinin double mutant mice. Gastroenterology. volum 126.
Academic article
Cui, GL; Koh, TJ; Chen, Duan; Zhao, Chun-Mei; Takaishi, S; Dockray, GJ; Varro, A; Rogers, AB; Fox, JG; Wang, T. (2004) Overexpression of glycine-extended gastrin inhibits parietal cell loss and atrophy in the mouse stomach. Cancer Research. volum 64.
Academic article
Aihara, T.; Fujishita, T.; Kanatani, K.; Furutani, K.; Nakamura, E.; Taketo, M.M.; Matsui, M.; Chen, Duan; Okabe, S.. (2003) Impaired gastric secretion and lack of trophic responses to hypergastrinemia in M3 muscarinic receptor-knockout mice. Gastroenterology. volum 125.
Academic article
Chen, Duan; Håkanson, R. (2003) Mechanism of gastric ECL-cell tumor induction: Observations in the rat. WHO IARC Technical Publication.
Academic article
Cui, G; Koh, T.; Chen, Duan; Zhao, C.M.; Dockery, J.; Varro, A; Fox, J; Wang, T. (2003) Overexpression of glycine-extended gastrin maintains acid secretion and prevents the development of preneoplasia in the stomach via reducing parietal cell lost in transgenic mice. Gastroenterology. volum 124.
Academic article
Cui, Guanglin; Koh, Theodore J.; Chen, Duan; Zhao, Chun-Mei; Dockray, G.J.; Varro, A.M.; Fox, J; Wang, T. (2003) Overexpression of glycine-extended gastrin maintains acid secretion and prevents the development of preneoplasia in the stomach via reducing parietal cell lost in transgenic mice. Gastroenterology. volum 124.
Feature article
Kopin, Alan S.; McBride, E.W.; Chen, Ci; Chen, Duan; Zhao, Chun-Mei; Beinborn, M. (2003) Identification of a series of CCK-2 receptor nonpeptide agonists: Sensitivity to stereochemistry and a receptor point mutation. PNAS. volum 100 (9).
Academic article
Kopin, Alan S.; McBride, E.W.; Ren, Y.; Chen, Duan; Zhao, C.M.. (2003) Identification of a series of CCK-2 receptor nonpeptide agonists: sensitivity to stereochemistry and a receptor point mutation. Proceedings of the National Academy of Sciences of the United States of America. volum 100.
Academic article
Martinsen, Tom Christian; Bakke, I; Chen, Duan; Aamo, T; Zahlsen, Kolbjørn; Waldum, Helge. (2003) Ciprofibrate stimulates the gastrin-producing cell by acting luminally on antral PPARa receptors. Gastroenterology. volum 124.
Academic article
Waldum, C.; Zhao, C.M.; Waldum, Helge; Halgunset, Jostein; Chen, Duan. (2003) Cheese-induced body weight is not accompained by an increase of gastric cells producing leptin, ghrelin, gastrin, or pancreastatin in mice. Scandinavian Journal of Laboratory Animal Science. volum 30.
Academic article
Waldum, Camilla; Zhao, Chun-Mei; Waldum, Helge; Halgunset, Jostein; Chen, Duan. (2003) Cheese-induced body weight gain is not accompanied by an increase of gastric cells producing leptin, gastrin, or pancreastatin in mice. Scandinavian Journal of Laboratory Animal Science. volum 30.
Academic article
Zhao, C-M; Wang, X.; Friis-Hansen, L; Waldum, Helge; Halgunset, Jostein; Wadstrøm, T; Chen, Duan. (2003) Chronic Helicobacter pylori infection results in gastric hypoacidity and hypergastrinemia in wild-type mice but vagally induced hypersecretion in gastroindeficient mice. Regulatory Peptides. volum 115.
Academic article
Zhao, Chun-Mei; Chen, D; Yamada, H.; Dornonville delaCour, C.; Lindström, E.; Persson, L.; Håkanson, R. (2003) Rat stomach ECL cells: mode of activation of histidine decarboxylase. Regulatory Peptides. volum 114 (1).
Academic article
Zhao, Chun-Mei; Chen, D; Yamada, H.; Dornonville delaCour, C.; Lindström, E.; Persson, L.; Håkanson, R. (2003) Rat stomach ECL cells: mode of activation of histidine decarboxylase. Regulatory Peptides. volum 114 (1).
Academic article
Zhao, Chun-Mei; Chen, Duan; Håkanson, Rolf. (2003) Rat stomach ECL cells: mode of activation of histidine decaroxylase. Regulatory Peptides. volum 114.
Academic article
Zhao, Chun-Mei; Wang, X; Friis-Hansen, L; Waldum, Helge; Halgunset, Jostein; Wadstrøm, T; Chen, Duan. (2003) Chronic Helicobacter pylori infection results in gastric hypoacidity and hypergastrinemia in wild-type mice but vagally induced hypersecretion in gastrin-deficient mice. Regulatory Peptides. volum 115.
Academic article
Chen, Duan; Håkanson, Rolf; Rehfeld, Jens F.; Zhao, Chun-Mei. (2002) CCK2 receptors are necessary for the differentiation and proliferation of ECL cells in mouse and rat stomach. Immunopharmacology. volum 10.
Academic article
Chen, Duan; Wallengren, Joanna. (2002) Local skin lesions in the rat after subcutaneous deposition of Capsaicin. Skin pharmacology and applied skin physiology. volum 15.
Academic article
Chen, Duan; Zhao, Chun-Mei; Håkanson, Rolf; Rehfeld, Jens F.. (2002) Gastric Phenotypic Abnormality in Cholecystokinin 2 Receptor Null Mice. Pharmacology and Toxicology. volum 91.
Academic article
Chen, Duan; Zhao, Chun-Mei; Wisam, Al-Haider; Håkanson, Rolf; Rehfeld, Jens F.; Kopin, Alan S.. (2002) Differentiation of Gastric ECL Cells is Altered in CCK2 Receptor-Deficient Mice. Gastroenterology. volum 123.
Academic article
Farrell, James J.; Taupin, Douglas; Koh, Theodore J.; Chen, Duan; Zhao, Chun-Mei; Podolsky, Daniel K.; Wang, Timothy C.. (2002) TFF2/SP-deficient mice show decreased gastric proliferation, increased acid secretion, and increased susceptibility to NSAID injury. The Journal of Clinical Investigation. volum 102 (2).
Academic article
Lehto-Axtelius, D.; Chen, Duan; Surve, V.V.; Håkanson, Rolf. (2002) Post-Gatrectomy Osteopenia in the Rat. Scandinavian Journal of Gastroenterology. volum 37.
Academic article
Björkqvist, Maria; Norlén, Per; Kitano, Masayuki; Chen, Duan; Zhao, Chun-Mei; Dornonville delaCour, D; Gagnemo-Persson, Rebecca; Håkanson, Rolf. (2001) Effects of CCK-2 receptor blockade on growth parameters in gastrointestinal tract and pancreas in rats. Pharmacology and Toxicology. volum 89.
Academic article
Chen, Duan; Zhao, Chun-Mei; Falkmer, Sture Emil; Waldum, Helge; Syder, Andrew; Gordon, Jeffrey. (2001) Ablation of Parietal Cells Is Associated with ECL-cell Hyperplasia in Transgenic Mice with a Genetically Engineered Ablation of Their Parietal Cell Lineage. Gastroenterology. volum 120 (5).
Academic article
Cui, G.-L.; Syversen, Unni; Chao, Chun-Mei; Chen, Duan; Waldum, Helge. (2001) Long-term Omeprazole treatment Suppresses Body Weight Gain and Bone Mineralization in Young Male Rats. Scandinavian Journal of Gastroenterology. volum 10.
Academic article
Cui, Guanglin; Syversen, Unni; Zhao, Chun-Mei; Chen, Duan; Waldum, Helge. (2001) Long-term omeprazole treatment suppress body weight gain and bone mineralization in young male rats. Scandinavian Journal of Gastroenterology. volum 36.
Academic article
Dornonville delaCour, D; Björkqvist, Maria; Sandvik, Arne Kristian; Håkanson, Rolf; Chen, D. (2001) A-like cells in the rat stomach contain ghrelin and do not operate under gastrin control. Regulatory Peptides. volum 99.
Academic article
Håkanson, Rolf; Chen, Duan; Lindström, Erik; Bernsand, Maria; Norlén, Per. (2001) Control of secretion from rat stomach ECL cells in situ and in primary culture. Scandinavian Journal of Clinical and Laboratory Investigation. volum 61.
Academic article
Lindström, Erik; Chen, Duan; Norlén, Per; Andersson, Kjell; Håkanson, Rolf. (2001) Control of gastric acid secretion: the gastrin-ECL cell - parietal cell axis. Comparative Biochemistry and Physiology A. volum 128.
Academic article
Nieuwenhove, Yves van; Chen, Duan; Willems, Gerard. (2001) Postprandial cell proliferation in the esophageal epithelium of rats. Regulatory Peptides. volum 97.
Academic article
Waldum, Camilla; Zhao, Chun-Mei; Chen, Duan. (2001) Are current textbooks good enough for physiology education? For example, the ECL-cells are missing. Advances in Physiology Education. volum 25.
Academic article
Zhao, Chun-Mei; Bakke, Ingunn; Skogaker, Nan Elisabeth Tostrup; Waldum, Helge; Håkanson, Rolf; Chen, Duan. (2001) Functionally impaired, hypertrophic ECL cells accumulate vacuoles and lipofuscin bodies. An ultrastructural study of ECL cells isolated from hypergastrinemic rats. Cell and Tissue Research.
Academic article
Zhao, Chun-Mei; Bakke, Ingunn; Tostrup-Skogaker, Nan; Waldum, Helge; Håkanson, Rolf; Chen, Duan. (2001) Functionally impaired, hypertrophic ECL cells accumulate vacuoles and lipofuscin bodies. An ultrastructural study of ECL cells isolated from hypergastrinemic rats. Cell and Tissue Research. volum 303.
Academic article
Chen, D; Zhao, CM; Norlen, P; Björkqvist, M; Ding, XQ; Kitano, M; Hakanson, R. (2000) Effect of cholecystokinin-2 receptor blockade on rat stomach ECL cells. A histochemical, electron-microscopic and chemical study. Cell and Tissue Research.
Academic article
Chen, Duan; Zhao, Chun-Mei; Dockray, Graham J.; Varro, Andrea; van Hoek, Alfred; Sinclair, Natalie F.; Wang, Timothy C.. (2000) Glycine-Extended Gastrin Synergizes With Gastrin 17 to Stimulate Acid Secretion in Gastrin-Deficient Mice. Gastroenterology. volum 119.
Academic article
Chen, Duan; Zhao, CM; Dockray, GJ; Varro, A; Hoek, AV; Sinclair, NF; Wang, TC; Koh, TJ. (2000) Glycine-Extended Gastrin Synergizes With Gastrin 17 to Stimulate Acid Secretion in Gastrin-Deficient Mice. Gastroenterology.
Academic article
Norlen, P.; Lindstrøm, E.; Zhao, Chun-Mei; Kitano, M.; Chen, Duan; Andersson, K.; Håkansson, R.. (2000) alpha-fluoromethylhistidine depletes histamine from secreting but not from non-secreting rat stomach ECL-cells. European Journal of Clinical Pharmacology. volum 14 (400).
Academic article
Norlèn, P; Lindström, E; Zhao, CM; Kitano, M; Chen, D; Andersson, K; Håkanson, R. (2000) x-Fluromethylhistidine depletes histamine from secreting but not from non-secreting rat stomach ECL cells. European Journal of Pharmacology: Environmental Toxicology and Pharmacology.
Academic article
Syversen, Unni; Waldum, HL; Slørdahl, K; Chen, D. (2000) Synergistic effects of the pesticides toxaphene and dieldrin on bone mineral density in female rats. Journal of Bone and Mineral Research. volum 15.
Academic article
Wang, TC; Dangler, CA; Chen, D; Goldenring, JR; Koh, T; Raychowdhury, R; Coffey, RJ; Ito, S; Varro, A; Dockray, GJ; Fox, JG. (2000) Synergistic Interaction Between Hypergastrinemia and Helicobacter Infection in a Mouse Model of Gastric Cancer. Gastroenterology.
Academic article

Part of book/report

Zhao, Chun-Mei; Johannessen, Helene; Kodama, Yosuke; Kulseng, Bård; Chen, Duan. (2013) Galanin. Handbook of Biologically Active Peptides.
Chapter
Chen, Duan. (2004) Absence of the cholecystokinin2 receptor alters the structure and function of gastric parietal and ECL cells. Gastrin in the New Millennium.
Academic chapter/article/Conference paper
Chen, Duan. (2004) ECL cells in a physiological context. Gastrin in the New Millennium.
Academic chapter/article/Conference paper

Teaching

Courses

Media

2023

Academic lecture

Andersen, Gøran Troseth; Lanevski, Aleksandr; Rabben, Hanne-Line; Geithus, Simon; Resell, Mathilde Victoria; Kodama, Yosuke; Tomita, Hiroyuki; Grønbech, Jon Erik; Wang, Timothy Cragin; Zhao, Chun Mei; Chen, Duan. (2023) GASTRIC INTESTINAL METAPLASIA VS. GASTRIC ADENOCARCINOMA OF PATIENTS: DISCTICT PHENOTYPIC TRAITS IN TRANSCRIPTOMICS. Digestive Disease Week 2023 ; Chicargo. 2023-05-05 - 2023-05-09.
Academic lecture

Resell, Mathilde Victoria; Rabben, Hanne-Line; Amrurkar, Manoj; Hagen, Lars; Batra, Surinder K.; Verbeke, Caroline Sophie; Wang, Timothy Cragin; Chen, Duan; Zhao, Chun Mei. (2023) INTEGRATIVE PROTEOMICS REVEALS TRANSLATIONAL POTENTIAL OF TARGETS FOR PANCREATIC DUCTAL ADENOCARCINOMA. Digestive Disease Week 2023 ; Chicargo. 2023-05-05 - 2023-05-09.
Academic lecture

Zhao, Chun Mei; Rabben, Hanne-Line; Resell, Mathilde Victoria; Olsen, Magnus Kringstad; Cai, Xing; Zhang, Haiying; Batra, Surinder K.; Lyden, David C; Wang, Timothy Cragin; Chen, Duan. (2023) ARREST OF EXOCYTOSIS/ENDOCYTOSIS COUPLING INHIBITS PROGRESSION OF PANCREATIC DUCTAL ADENOCARCINOMA IN MICE. Digestive Disease Week 2023 ; Chicargo. 2023-05-05 - 2023-05-09.

2022

Academic lecture

Chen, Duan; Zhao, Chun-Mei. (2022) Peptides and the Gut: the unfinished story of gastrin. 24th International Symposium on Regulatory Peptides (RegPep24) . IRPS; University of Stirling, Scotland. 2022-08-01 - 2022-08-05.
Academic lecture

Zhao, Chun-Mei; Chen, Duan; Rabben, Hanne-Line; Wang, Timothy Cragin. (2022) Drug-Repurposing for Treatment of Gastric Cancer. 24th International Symposium on Regulatory Peptides (RegPep24) . IRPS; University of Stirling, Scotland. 2022-08-01 - 2022-08-05.

2019

Academic lecture

Rabben, Hanne-Line; Andersen, Gøran Troseth; Olsen, Magnus Kringstad; Wang, Timothy Cragin; Chen, Duan; Zhao, Chun-Mei. (2019) 531 – Targeting Nerve-Cancer Metabolism Improved Overall Survival in Aged Mice with Gastric Cancer. Scientific meeting . Digestive Disease Week; San Diego, CA. 2019-05-18 - 2019-05-21.
Poster

Zhao, Chun-Mei; Zhu, Yanping; Hao, Yanpeng; Wang, Zhiqiang; Wang, Li; Chen, Duan. (2019) USE OF PATIENT-DERIVED TUMOR XENOGRAFT MODEL TO GUIDETREATMENT DECISIONS FOR PATIENTS. DDW 2019 . DDW 2019; San Diego. 2019-05-18 - 2019-05-21.

2016

Academic lecture

Beisvag, Vidar; Bakke, Ingunn; Andersen, Gøran Troseth; Zhao, Chun-Mei; Chen, Duan; Waldum, Helge; Sandvik, Arne Kristian. (2016) Signet ring cell carcinomas identified as a molecular subtype of gastric cancer. Digestive Disease Week 2016 . American Society for Gastrointestinal Endoscopy (ASGE); San Diego, CA. 2016-05-21 - 2016-05-24.
Interview

Chen, Duan; Zhao, Chun-Mei; Olsen, Magnus Kringstad; Rabben, Hanne-Line; Andersen, Gøran Troseth. (2016) Fant hormon som kan bli medisin mot diabetes. gemini.no [Internett]. 2016-05-15.
Interview

Chen, Duan; Zhao, Chun-Mei; Olsen, Magnus Kringstad; Rabben, Hanne-Line; Andersen, Gøran Troseth. (2016) Nytt norsk funn kan ta knekken på diabetes. tv2.no [Internett]. 2016-05-15.
Interview

Olsen, Magnus Kringstad; Chen, Duan; Zhao, Chun-Mei. (2016) NTNU-forskere fant hormon som kan ta knekken på diabetes. abcnyheter.no [Internett]. 2016-05-16.

2015

Academic lecture

Andersen, Gøran Troseth; Kodama, Yosuke; Hayakawa, Yoku; Vettukattil, Riyas; Grønbech, Jon Erik; Chen, Duan; Zhao, Chun-Mei. (2015) Glutamine Metabolism As a Therapeutic Target for Gastric Cancer: Effects of Vagotomy Gastroenterology,Volume 148, Issue 4, Supplement 1, April 2015, Pages S-565–S-566. DDW 2015 . DDW 2015; Washington DC,. 2015-05-16 - 2015-05-18.
Academic lecture

Andersen, Gøran Troseth; Kodama, Yosuke; Hayakawa, Yoku; Vettukattil, Riyas; Grønbech, Jon Erik; Wang, Timothy C.; Chen, Duan; Zhao, Chun-Mei. (2015) Glutamine metabolism as a therapeutic target for gastric cancer: effects of vagotomy. AACR 2015 . American Association of Cancer Research; Philadelphia, USA. 2015-04-18 - 2015-04-20.
Lecture

Andersen, Gøran Troseth; Kodama, Yosuke; Rabben, Hanne-Line; Hayakawa, Yoku; Vettukattil, Riyas; Grønbech, Jon Erik; Wang, Timothy C.; Chen, Duan; Zhao, Chun-Mei. (2015) GLUTAMINE METABOLISM AS A THERAPEUTIC TARGET FOR GASTRIC CANCER: EFFECTS OF DENERVATION. 15th International Conference on ULcer Research . IUPHAR; Ottawa. 2015-10-01 - 2015-10-04.
Lecture

Andersen, Gøran Troseth; Zhao, Chun-Mei; Chen, Duan. (2015) Denervation suppresses gastric tumorigenesis by inhibiting WNT signaling: a preclinical study. WNT and SHH meets Energy Metabolism . Oslo University; Heningsvør. 2015-05-25 - 2015-05-28.
Academic lecture

Cai, Xing; Rabben, Hanne-Line; Chen, Duan; Zhao, Chun-Mei. (2015) Inhibition of metabolism and mTOR signalling for treatment of gastric cancer: A preliminary study in vitro and in animal model of spontaneous gastric cancer. WNT and SHH meets Energy Metabolism ; Henningsvære. 2015-05-25 - 2015-05-28.
Documentary

Egelandsdal, Bjørg; Haug, Anna; Chen, Duan. (2015) Ingen grunn til kjøttpanikk. Aftenposten [Avis]. 2015-10-29.
Academic lecture

Hayakawa, Yoku; Asfaha, Samuel; Renz, Bernhard W.; Westphalen, Christoph B.; Tailor,, Yagnesh H.; Nagar,, Karan K.; Worthley, Daniel L.; Chen, Duan; Wang, Timothy C.. (2015) NGF Promotes Gastrointestinal Cancer Development Through Tumor-Associated Neurogenesis. DDW2015 ; Washington DC,. 2015-05-16 - 2015-05-18.
Academic lecture

Hayakawa, Yoku; Samuel, Asfaha; Renz, Bernhard W.; Westphalen, Christoph B.; Tailor, Yagnesh H.; Nagar, Karan K.; Worthley, Daniel L.; Chen, Duan; Wang, Timothy C.. (2015) NGF promotes gastrointestinal cancer development through tumor-associated neurogenesis. AACR 2015 ; Philadelphia, USA. 2015-04-18 - 2015-04-20.
Academic lecture

Olsen, Magnus Kringstad; Johannessen, Helene; Kodama, Yosuke; Kulseng, Bård Eirik; Zhao, Chun-Mei; Chen, Duan. (2015) Comparison of different surgical procedures in animal models for a better consideration of personalized bariatric surgery. DDW 2015 . DDW 2015; Washington DC,. 2015-05-16 - 2015-05-18.

2014

Interview

Chen, Duan. (2014) Behandler kreft med botox. abcnyheter [Internett]. 2014-09-01.
Interview

Chen, Duan. (2014) Botox Injections Could Be Used To Treat Stomach Cancer, Experts Say. huffington post UK [Internett]. 2014-08-22.
Interview

Chen, Duan. (2014) Botox May Slow Tumor Growth In Stomach Cancer. the US daily [Internett]. 2014-08-22.
Interview

Chen, Duan. (2014) Botox brukes mot langt mer enn rynker. adressavisen [Avis]. 2014-09-06.
Interview

Chen, Duan. (2014) Botox could halt stomach cancer. the telegraph [Internett]. 2014-08-22.
Interview

Chen, Duan. (2014) Botox 'highly effective' treatment of gastric cancer. Irish independent [Internett]. 2014-08-22.
Interview

Chen, Duan. (2014) Botox injections may halt cancer growth. pressTV [Internett]. 2014-09-01.
Interview

Chen, Duan. (2014) Botox injections may halt cancer growth: Research. null [Internett]. 2014-09-01.
Interview

Chen, Duan. (2014) Botox may have cancer fighting role. BBC new [Internett]. 2014-08-22.
Interview

Chen, Duan. (2014) Botox may slow tumor growth in stomach cancer. Indian Mirror [Internett]. 2014-08-22.
Interview

Chen, Duan. (2014) Botox may slow tumor growth in stomach cancer. japan today [Internett]. 2014-08-22.
Interview

Chen, Duan. (2014) Botox may slow tumour growth in stomach. MSN new zealand [Internett]. 2014-08-22.
Interview

Chen, Duan. (2014) Botox may slow tumour growth in stomach. Melbourne age [Internett]. 2014-08-22.
Interview

Chen, Duan. (2014) Botox mot kreft. NRK nyheter [TV]. 2014-08-22.
Interview

Chen, Duan. (2014) Botox mot kreft. st olavs hospital [Internett]. 2014-08-27.
Interview

Chen, Duan. (2014) Botox testas mot cancer. Läkmedelsvärlden [Internett]. 2014-08-27.
Interview

Chen, Duan. (2014) Cáncer gástrico: El Botox podría ser una alternativa a la quimioterapia?. medical press [Internett]. 2014-08-22.
Interview

Chen, Duan. (2014) El bótox podría usarse para tratar el cáncer. null [Internett]. 2014-08-25.
Interview

Chen, Duan. (2014) Las inyecciones de bótox podrían servir como tratamiento del cáncer de estómago. null [Internett]. 2014-08-22.
Interview

Chen, Duan. (2014) Le BOTOX pour stopper le cancer de l'estomac – Science Translational Medicine -. santeBlog [Internett]. 2014-08-22.
Interview

Chen, Duan. (2014) Le Botox freine la progression du cancer de l'estomac. Canoe [Internett]. 2014-08-22.
Interview

Chen, Duan. (2014) Magenkrebs: Nervengift könnte Wachstum aufhalten. aponet.de [Internett]. 2014-08-22.
Interview

Chen, Duan. (2014) NTNU-forskning vekker internasjonal oppsikt. NRK trøndelag [Internett]. 2014-08-20.
Interview

Chen, Duan. (2014) New Wrinkle for Botox: Drug May Treat Stomach Cancers. yahoo uk [Internett]. 2014-08-22.
Interview

Chen, Duan. (2014) Skal teste Botox i kampen mot kreft. Agder Flekkefjord tidende [Internett]. 2014-08-22.
Interview

Chen, Duan. (2014) Skal teste Botox mot kreft. p4 [Radio]. 2014-08-22.
Interview

Chen, Duan. (2014) Studio: botulino in aiuto contro il tumore allo stomaco. Salute24 [Internett]. 2014-08-22.
Interview

Chen, Duan. (2014) Study: Botox Could Prevent Spread of Gastric Cancer -. cancernetwork [Internett]. 2014-09-11.
Interview

Chen, Duan. (2014) Tester Botox i kampen mot kreft. Telemarksavisa [Avis]. 2014-08-22.
Interview

Chen, Duan. (2014) The other use for botox. the sydney morning herald [Internett]. 2014-08-22.
Interview

Chen, Duan. (2014) Treating cancer with Botox. Health canal [Internett]. 2014-09-01.
Interview

Chen, Duan. (2014) Treating cancer with botox. Nordic life science news [Internett]. 2014-08-27.
Interview

Chen, Duan. (2014) Treating gastric cancer -- with Botox. bionity.com [Internett]. 2014-08-22.
Interview

Chen, Duan. (2014) Ботокс поможет победить рак желудка. null [Internett]. 2014-08-22.
Interview

Chen, Duan; Andersen, Gøran Troseth; Kulseng, Bård Eirik; Tronvik, Erling. (2014) – Botox kan bli en ny kreftkur. NRK.no [Internett]. 2014-04-07.
Poster

Johannessen, Helene; Olsen, Magnus Kringstad; Cassie, Nikki; Barrett, Perry; Rehfeld, Jens F.; Holst, Jens J.; Kulseng, Bård Eirik; Zhao, Chun-Mei; Chen, Duan. (2014) Preclinical Trial of Gastric Injection of Botulinum Toxin Type A as Weight-Loss-Surgery. Digestive Disease Week 2014 ; Chicago. 2014-05-03 - 2014-05-06.
Poster

Johannessen, Helene; Revesz, David; Kodama, Yosuke; Cassie, Nikki; Skibicka, Karolina P.; Olsen, Magnus Kringstad; Lyle, Robert; Barrett, Perry; Dickson, Suzanne L.; Holst, Jens J.; Rehfeld, Jens F.; Takeuchi, Koji; Kulseng, Bård Eirik; Thorlin, Thorleif; Ben-Menachem, Elinor; Zhao, Chun-Mei; Chen, Duan. (2014) The role of vagus nerve in the brain-gut axis: a target for obesity treatment. WCP2014 . 17th World Congress of Basic & Clinical Pharmacology; Cape Town. 2014-07-13 - 2017-07-18.
Interview

Kulseng, Bård Eirik; Tronvik, Erling; Andersen, Gøran Troseth; Chen, Duan. (2014) botox. NRK puls [TV]. 2014-04-07.
Academic lecture

Zhao, Chun-Mei; Hayakawa, Yoku; Kodama, Yosuke; Westphalen,, Christoph Benedikt; Muthupalani,, Sureshkumar; Johannessen, Helene; Andersen, Gøran Troseth; Fox,, James G.; Wang,, Timothy C.; Chen, Duan. (2014) Preclinical trial of botulinum toxin type A for treatment of gastric Cancer. WCP2014 . WCP 2014, 17th World Congress of Basic & Clinical Pharm; Cape Town. 2014-07-13 - 2017-07-18.
Poster

Zhao, Chun-Mei; Kidd, Mark; Chen, Duan. (2014) Triple Roles of Autophagy in Cytoprotection, Cell Death and Tumorigenesis with Special Reference to Gastric ECL cell. WCP2014 . 17th World Congress of Basic & Clinical Pharmacology; Cape Town. 2014-07-13 - 2017-07-18.
Academic lecture

Zhao, Chun-Mei; Mark, Kidd,; Chen, Duan. (2014) Triple Roles of Autophagy in Cytoprotection, Cell Death and Tumorigenesis With Special Reference to Gastric ECL Cells. DDW 2014 . DDW; Chicago. 2014-05-03 - 2014-05-06.
Poster

Zhao, Chun-Mei; Yoku, Hayakawa; Westphalen,, Christoph B; Muthupalani,, Sureshkumar; Johannessen, Helene; Andersen, Gøran Troseth; Fox,, James G; Wang,, Timothy C.; Chen, Duan. (2014) Preclinical Trial of Botulinum Toxin Type a Injection in the Treatment of Gastric Cancer. DDW 2014 . DDW; Chicago, USA. 2014-05-03 - 2014-05-06.

2013

Academic lecture

Johannessen, Helene; Kodama, Yosuke; Chen, Duan; Zhao, Chun-Mei. (2013) WP7: Vagal involvement in brain signaling and response to food and gut hormones. Full4Health Project Meeting . Full4Health; Lille. 2013-03-06 - 2013-03-08.
Academic lecture

Johannessen, Helene; Revesz, David; Kodama, Yosuke; Cassie, Nikki; Skibicka, Karolina P.; Lyle, Robert; Bettencourt, Girao Paulo Jorge; Popovic, Miroljub; Witter, Menno; Barrett, Perry; Dickson, Suzanne L.; Holst, Jens J.; Rehfeld, Jens F.; Takeuchi, Koji; Kulseng, Bård; Thorlin, Thorleif; Ben-Menachem, Elinor; Zhao, Chun-Mei; Chen, Duan. (2013) Role of the vagus nerve in the gut-brain axis revealed by stimulation and blockade of the gastric vagus nerve. The 1st National PhD Conference in Neuroscience . NRSN; Stiklestad. 2013-09-10 - 2013-09-11.
Academic lecture

Johannessen, Helene; Revesz, David; Kodama, Yosuke; Cassie, Nikki; Skibicka, Karolina P.; Lyle, Robert; Bettencourt, Paulo; Miroljub, Popovic; Witter, Menno; Barrett, Perry; Dickson, Suzanne L.; Koji, Takeuchi; Kulseng, Bård; Thorlin, Thorleif; Ben-Menachem, Elinor; Zhao, Chun-Mei; Chen, Duan. (2013) Role of the vagus nerve in the gut-brain axis revealed by stimulation and blockade of the gastric vagus nerve. Digestive Disease Week 2013 ; Orlando, Florida. 2013-05-18 - 2013-05-21.
Poster

Kodama, Yosuke; Zhao, Chun-Mei; Muthupalani, Sureshkumar; Flatberg, Arnar; Friedman, Richard A.; Sandvik, Arne; Beisvag, Vidar; Johannessen, Helene; Hayakawa, Yoku; Tomita, Hiroyuki; Hara, Akira; Westphalen, Christoph B.; Quante, Michael; Kaneko, Kazuhiro; Fox, James G.; Wang, Timothy C.; Chen, Duan. (2013) Denervation Suppresses Gastric Cancer Initiation and Progression Through Inhibition of the Cancer Niche. Digestive Disease Week 2013 ; Orlando, Florida. 2013-05-18 - 2013-05-21.
Academic lecture

Chen, Duan. (2013) Novel Strategy for Control of Gastric Cancer: Surgical or Pharmocological Denervation. The 4th JCA-AACR Special Joint Confence--The Latest Advances in Gastric Cancer Research: From Basic Science to Therapeutics ; Tokyo. 2013-12-16 - 2013-12-18.
Academic lecture

Chen, Duan; Yosuke, Kodama; Zhao, Chun-Mei; Sureshkuma, Muthupalani; Yoku, Hayakawa; Flatberg, Arnar; Friedman, Richard A.; Sandvik, Arne; Beisvag, Vidar; Johannessen, Helene; Tomita, Hiroyuki; Hara, Akira; Westphalen, Christoph B.; Quante, Michael; Li, Zhishan; Gershon, Micheal D; Keneko, Kazuhiro; Fox, James G.; Wang, Timothy C.. (2013) Denervation suppresses Gastric Tumorigenesis. 15th Taithotoyama International Symposium on Gastroenterology. ; Tokyo. 2013-09-26 - 2013-09-28.
Academic lecture

Okabe, Susumu; Okamoto, T; Matsui, Hiroshi; Zhao, Chun-Mei; Chen, Duan. (2013) A potential New Therapy for Gastric Cancer: Acetic Acid Induces Cancer Cell Death. 15th Taithotoyama International Symposium on Gastroenterology. ; Tokyo. 2013-09-26 - 2013-09-28.
Academic lecture

Oostindjer, Marije; Chen, Duan. (2013) Does a healthy brain prevent cancer, The role of the brain-gut axis. How can we approach consensus on the healthiness of red meat? ; 2013-11-06 - 2013-11-07.
Poster

Røe, Oluf Dimitri; Chen, Duan; Chen, Wu; Chen, Yijiang; Zhi, Xiaofei. (2013) DNA repair suppression and effect of cisplatin in mesothelioma and lung cancer cell lines. ASCO 2013 . ASCO; Chicago. 2013-05-30 - 2013-06-03.
Academic lecture

Zhao, Chun-Mei; Chen, Duan. (2013) The morphologic pathway of exocytosis, crinophagy and autophagy in gastric ECL cells and gastric carcinoids (ECLomas). 15th Taithotoyama International Symposium on Gastroenterology ; Tokyo. 2013-09-26 - 2013-09-28.
Academic lecture

Øverby, Anders; Zhao, Chun-Mei; Yosuke, Kodama; Atle M, Bones; Chen, Duan. (2013) Naturally Occurring Isothiocyanates Inhibit Gastric Cancer Cell Growth by Disruption of Microtubules. 15th Taithotoyama International Symposium on Gastroenterology. ; Tokyo. 2013-09-26 - 2013-09-28.

2012

Academic lecture

Chen, Duan; Zhao, Chun-Mei. (2012) Genetic dissection of the mechnism underlying gastric acid secretion. A Satellite Symposium of IUPHAR, GI section, . IUPHAR; Tokyo. 2012-07-12 - 2012-07-14.
Academic lecture

Johannessen, Helene; Kodama, Yosuke; Zhao, Chun-Mei; Chen, Duan. (2012) Potential role of the afferent and efferent vagus nerve in control of eating behavior: new target for obesity therapy. A Satellite Symposium of IUPHAR, GI section, International Ulcer Week 2012 . The International Union of Basic and Clinical Pharmacology; Tokyo. 2012-07-12 - 2012-07-14.
Academic lecture

Kodama, Yosuke; Zhao, Chun-Mei; Quante, Michael; Muthupalani, Sureshkumar; Flatberg, Arnar; Friedman, RA; Sandvik, AK.; Fox, JG; Wang, TC; Chen, Duan. (2012) Potential role of the vagus nerve in gastric tumorigenesis: new target fro cancer therapy. A Satellite Symposium of IUPHAR, GI section, International Ulcer Week . IUPHAR; Tokyo. 2012-07-12 - 2012-07-14.
Academic lecture

Zhao, Chun-Mei; Chen, Duan. (2012) Life cycle of the secretory organelles and signal pathways in gastric ECL cells. A Satellite Symposium of IUPHAR, GI section, International Ulcer Week 2012 . IUPHAR; Tokyo. 2012-07-12 - 2012-07-14.

2011

Poster

Johannessen, Helene; Kodama, Yosuke; Cao, HaiLong; Kulseng, Baard; Zhao, Chun-Mei; Chen, Duan. (2011) Eating Behavior in Rats Subjected to Ileum Transposition and Sleeve Gastrectomy. DDW 2011 . DDW 2011; Chicargo. 2011-05-06 - 2011-06-12.
Poster

Kodama,, Yosuke; Johannessen, Helene; Furnes, Marianne Waldum; Zhao, Chun-Mei; Kulseng, Baard; Chen, Duan. (2011) Energy Metabolism Following High-Fat Diet and Bariatric Surgeries (Gastric Bypass, Sleeve Gastrectomy, Duodenal Switch and Ileum Transposition) in Rats. DDW 2011 . DDW 2011; Chicargo. 2011-05-06 - 2011-05-12.
Poster

Kodama,, Yosuke; Zhao, Chun-Mei; Quante, Michael; Muthupalani, Sureshkumar; Flatberg, Arnar; Sandvik, Arne K.; Fox, James G.; Wang, Timothy C.; Chen, Duan. (2011) Evidence for Mechanism of Vagal Innervation in Gastric Cancer Initiation Involving Signaling Pathways Governing Stem Cells in Mice. DDW 2011 . DDW 2011; Chicargo. 2011-05-06 - 2011-05-12.
Poster

Zhao, Chun-Mei; Kodama, Yosuke; Flatberg, Arnar; Sandvik, Arne K.; Chen, Duan. (2011) Stomach-Bone Axis: Possible Involvement of Signaling Pathways and Vitamin D Governing Bone Metabolism. DDW 2011 . DDW 2011; Chicargo. 2011-05-06 - 2011-06-12.
Academic lecture

Johannessen, Helene; Kodama, Yosuke; Zhao, Chun-Mei; Chen, Duan. (2011) WP7: Vagal involvement in brain signaling and response to food and gut hormones. Full4Health Project Meeting . Full4Health; Maastricht. 2011-11-06 - 2011-11-09.
Academic lecture

Vigen, Reidar Alexander; Kidd, Mark; Modlin, Irvin; Chen, Duan; Zhao, Chun-Mei. (2011) Ultrastructral Evidence for a Mechanism of ECL Cell Transformation to Gastric Carcinoid in Mastomys Involving Impairment of Autophagy and Loss of Gastrin Control. DDW 2011 . DDW 2011; Chicargo. 2011-05-06 - 2011-05-12.

2010

Academic lecture

Kodama, Yosuke; Zhao, Chun-Mei; Kulseng, Baad; Chen, Duan. (2010) Eating Behavior in Rats Subject to Vagotomy, Sleeve Gastrectomy and Duodenal Switch. DDW 2010 ; New orleans. 2010-05-01 - 2010-05-05.
Poster

Zhao, Chun-Mei; Kodama, Yosuke; Flatberg, Arnar; Anderssen, Endre; Sandvik, Arne Kristian; Chen, Duan. (2010) Gastric ECL cells, rather than gastric acid, play an important role in gut-bone axis. DDW 2010 ; New Orleans. 2010-05-01 - 2010-05-05.
Academic lecture

Chen, Duan. (2010) GI pharmacology: the importance of bench-to-bedside-and-back concept. The 16th World Congress on Basic and Clinical Pharmacology . IUPHAR; Copenhagen. 2010-07-17 - 2010-07-22.
Academic lecture

Kodama, Yosuke; Zhao, Chun-Mei; Quante, Michael; Muthupalani, Sureshkumar; Fox, James G.; Wang, Timothy C.; Chen, Duan. (2010) Truncal vagotomy inhibited gastric cancer initiation in the INS-GAS mouse model. DDW 2010 ; New Orleans. 2010-05-01 - 2010-05-05.

2009

Academic lecture

Chen, Duan; Furnes, Marianne; Zhao, Chun-Mei. (2009) Translational research on obesity: from bedside to bench. 13th internatuonal conference on gastrointestinal research /13th international conference on ulcer research . ICUR; Split, Crocia. 2009-10-10 - 2009-10-16.
Academic lecture

Arum, Carl-Jørgen; Anderssen, Endre; Zhao, Chun-Mei; Chen, Duan. (2009) Gene expression profiles of bladder cancer: Comparison between rat bladder cancer model and human bladder cancer patients. Bioinformatics Forum for Young Scientists . NTNU; Selbu. 2009-04-24 - 2009-04-26.
Academic lecture

Song, Zhigang; Bhagat, Govind; Baik, Gwang Ho; Gordon, Shanisha A.; Mitchell, Anthony; Zhao, Chun-Mei; Chen, Duan; Dannenberg, Andrew; Wang, Timothy C.. (2009) Development of a Mouse Model of Inflammation-Dependent Pancreatic Cancer. DDW 2009 . DDW 2009; Chicago. 2009-05-30 - 2009-06-04.
Poster

Zhao, Chun-Mei; Andersen, Endre; Chen, Duan. (2009) Gene Expression and Pathway Analysis of Mouse Stomach: Gastric ECL Cells May Produce Vitamin D. DDW 2009 . DDW 2009; Chicago. 2009-05-30 - 2009-06-04.
Academic lecture

Zhao, Chun-Mei; Chen, Duan. (2009) Differentiation of Gastric ECL Cells in CCK 1+2 Receptor Double Knockout Mice. DDW 2009 . DDW 2009; Chicago. 2009-05-30 - 2009-06-04.
Academic lecture

Zhao, Chun-Mei; Friis-Hansen, L; Wang, Timothy C.; Chen, Duan. (2009) Roles of helicobacter pylori(H.pylori), gastrin and gastric acid in gastric carcinogenesis. Studies using gastrin gene engineered mouse model. 13th International Conference on Gastrointestinal Research ; 2009-09-10 - 2010-09-16.
Academic lecture

Zhao, Chun-Mei; Friis-Hansen, L; Wang, Timothy C.; Chen, Duan. (2009) Roles of helicobacter pylori(H.pylori), gastrin and gastric acid in gastric carcinogenesis. Studies using gastrin gene engineered mouse model. 13th international conference on gastrointestinal research/13th international conference on ulcer research . ICUR/ICGR; Split. 2009-10-10 - 2009-10-16.

2008

Academic lecture

Arum, Carl-Jørgen; Anderssen, Endre; Tømmerås, Karin; Zhao, Chun-Mei; Chen, Duan. (2008) Vertsimmunrespons til urotelialkreftcelleinvasjon: DNA mikroarray og pathway analyse av ortotopisk rotteblærekreftmodell. Kirurgisk Høstmøte 2008 . Norsk Kirurgisk Forening; Oslo. 2008-10-20 - 2008-10-24.
Academic lecture

Chen, Duan. (2008) Genetic and environmental factors in stomach cancer gastrin, H. Pylori and snus. Tirsdagsmøte for DMF, NTNU og St. Olavs Hospital . IKM; Trondheim. 2008-05-06.

2007

Academic lecture

Arum, Carl-Jørgen; Andersen, Endre; Tømmerås, Karin; Zhao, Chun-Mei; Chen, Duan. (2007) Gene expression profiling and pathway analysis of orthotopic rat bladder cancer model. 41 st Annual Meeting of the European Society for Clinical Investigation ; 2007-04-17 - 2007-04-20.
Academic lecture

Arum, Carl-Jørgen; Andersen, Endre; Tømmerås, Karin; Zhao, Chun-Mei; Chen, Duan. (2007) Pathway analyse av orthotopisk rotteblære kreftmodell og human blære kreft. Kirurgisk Høstmøte 2007 . Norsk Kirurgisk Forening; 2007-10-23 - 2007-10-26.
Academic lecture

Chen, Duan. (2007) Mechanism of gastric acid secretion: history and state-of-the art. Doshisha School of Pharmacy ; 2007-12-05 - 2007-12-06.
Academic lecture

Chen, Duan. (2007) Mechanism of gastric acid secretion: known and unknown pathways revealed in a series of knockout mouse strains. Kyoto Pharmaceutical University and NTNU ; 2007-12-04 - 2007-12-05.
Interview

Chen, Duan. (2007) Snus kan føre til magekreft. Adresseavisen [Avis]. 2007-03-29.
Academic lecture

Gederaas, Odrun Arna; Larsen, Eivind La Puebla; Randeberg, Lise Lyngsnes; Arum, Carl-Jørgen; Hjelde, Astrid; Zhao, Chun-Mei; Chen, Duan; Krokan, Hans Einar; Svaasand, Lars O.. (2007) 5-ALA-based photodynamic therapy in an experimental bladder tumour model. Forskningsseminar, Lunds Universitets Medisinska Lasercentrum . Universitetet i Lund; Lund. 2007-02-20 - 2007-02-20.
Academic lecture

Gederaas, Odrun Arna; Randeberg, Lise Lyngsnes; Larsen, Eivind La Puebla; Hjelde, Astrid; Arum, Carl-Jørgen; Brunsvik, Anders; Zhao, Chun-Mei; Chen, Duan; Svaasand, Lars O.; Krokan, Hans Einar. (2007) Effects of hexyl 5-aminolevulinate and light in a rat bladder cancer model. 12 th Congress, European Society for Photobiology, Bath . ESP; Bath. 2007-09-01 - 2007-09-06.
Poster

Zhao, Chun-Mei; Furnes, Marianne Waldum; Stenström, Björn Stenström; Tømmerås, Karin; Chen, Duan. (2007) Reduced food intake but increased appetite in rats subjected to gastrectomy. DDW 2007 . DDW 2007; Washinton DC. 2007-05-19 - 2007-05-23.
Poster

Zhao, Chun-Mei; Karlsson, Bjørn; Chen, Duan. (2007) Swedish smokeless tobacco (snus) accelerates gastric cancer in a Helicobacter pylori mouse model. DDW 2007 . DDW 2007; Washington Dc. 2007-05-19 - 2007-05-23.
Poster

Zhao, Chun-Mei; Marianne, F; Tømmerås, Karin; Skoglund, Trine; Chen, Duan. (2007) Localization of Obestatin and Ghrelin in Gastrointerological Tract and Pancreas of Rats. Digestive Disease Week 2007 . DDW 2007; Washinton DC. 2007-05-19 - 2007-05-23.

2006

Poster

Helge, Eli; Zhao, Chun-Mei; Follestad, Turid; van den Ijssel, Paul; Eijk, Paul p; Ylstra, Bauke; Falkmer, Ursula; Chen, Duan. (2006) Gene expression profile of stomach in response to food intake in mice. Digestive Disease Week . AGA Council; Los Angeles. 2006-05-19 - 2006-05-25.
Academic lecture

Zhao, Chun-Mei; Chen, Duan. (2006) Somatostatin receptor type 2 knockout mice display inhibitory effect of galanin on ECL cells but enhanced action of gastrin on parietal cells. Midt-Norsk Forskningforum i Gastroenterologi. . Midt-Norsk Forskningforum; Meråker. 2006-04-17 - 2006-04-19.
Poster

Zhao, Chun-Mei; Chen, Duan. (2006) Somatostatin receptor type 2 knockout mice display inhibitory effect of galanin on ECL cells but enhanced action of gastrin on parietal cells. Ammerican Gastroenterology Association (DDW) ; LA, CA. 2006-05-20 - 2006-05-25.
Academic lecture

Zhao, Chun-Mei; Chen, Duan; Helge, Eli. (2006) The transcriptomes of stomach in response to food intake in mice. Midt-Norsk Forskningforum i Gastroenterologi. Meråker, Norge ; Meråker. 2006-04-17 - 2006-04-19.
Poster

Zhao, Chun-Mei; Chen, Duan; Stenström, Björn; Furnes, Marianne; Tømmerås, Karin; Arum, Carl-Jørgen; Syvenssen, Unni. (2006) Mechanisms of body weight loss after gastric bypass surgery in rats. DDW ; LA, CA. 2006-05-20 - 2006-05-26.

2005

Academic lecture

Arum, Carl Jørgen; Tømmerås, Karin; Gederaas, Odrun Arna; Anderssen, Endre; Zhao, Chun-Mei; Chen, Duan. (2005) Gene expression profiling of orthotopic rat bladder cancer model. International symposium . NTNU; Trondheim. 2005-12-09 - 2005-12-10.
Academic lecture

Furnes, Marianne Waldum; Karlsson, Bjørn; Chen, Duan. (2005) Comprehensive monitoring of food intake of rats subjected to gastric bypass. International Symposium on Translational Research . International Symposium on Translational Research; Trondheim. 2005-10-09 - 2005-12-10.
Academic lecture

Håkanson, R; Chen, Duan. (2005) Intracellular traffic of secretory organelles in ECL cells of stomach. BioScience 2005 - SECC . BioScience 2005 from genes to systems, SECC; Glasgow. 2005-07-17 - 2005-07-21.
Academic lecture

Karlsson, Bjørn; Tømmerås, Karin; Syversen, Unni; Zhao, Chun-Mei; Chen, Duan. (2005) Long-term effect of gastric bypass surgery on body composition and bone in rats. Midt-Norsk forskningsforum ; Meråker. 2005-04-08 - 2005-04-09.
Academic lecture

Larimar, E; Helge, E; Danielsen, S; Marthinsen, A-B; Falkmer, Ursula; Chen, Duan. (2005) Inhibition of bladder cancer rat cell line growth by green tea compound polyphenol epigallocatechinin-3-gallat and radiation. International Symposium on Translational Research . International Symposium on Translational Research; Trondheim. 2005-12-09 - 2005-12-10.
Academic lecture

Martinez, V; Piqueras, L; Taché, Y; Chen, Duan. (2005) Somatostatin receptor type 2 knockout mice display inhibitory effect of galanin on ECL cells but enhanced action of gastrin on parietal cells. International Symposium on Translational Research . International Symposium on Translational Research; Trondheim. 2005-12-09 - 2005-12-10.
Academic lecture

Tømmerås, Karin; Furnes, Marianne Waldum; Syversen, Unni; Dickson, S; Chen, Duan. (2005) Mechanisms of body weight loss after gastric bypass surgery. International Symposium on Translational Research . International Symposium on Translational Research; Trondheim. 2005-10-09 - 2005-12-10.
Academic lecture

Tømmerås, Karin; Syversen, Unni; Chen, Duan. (2005) Long-term effect of gastric bypass surgery on body composition and bone in rats. Midt-Norsk Forskningsforum . Midt-Norsk Forskningsforum i Gastroenterologi; Meråker. 2005-04-08 - 2005-04-09.
Academic lecture

Vigen, RA; Arum, Carl-Jørgen; Karlsson, Bjørn; Chen, Duan. (2005) A unique model for studying the physiology of gastrin: gastrocystoplasty. International Symposium on Translational Research . International Symposium on Translational Research; Trondheim. 2005-12-09 - 2005-12-10.

2003

Academic lecture

Chen, Duan. (2003) ECL-cell histamine: up-to-date. 7th Japanese Histamine Research Symposium . [Mangler data]; Kyoto, Japan. 2003-12-07.
Academic lecture

Chen, Duan; Wang, X.; Friis-Hansen, L; Waldum, Helge; Halgunset, Jostein; Wadstrøm, T. (2003) Chronic Helicobacter pylori infection may result in gastric cancer in hypergastrinemic mice but not in gastrin-deficient mice. Proceedings of International Conference on Applied Genomics - 9th ESACP/16th ISDQP Meeting (ICAG-2003) Focus on: Translational Genomics in Oncology . [Mangler data]; Nederland. 2003-10-04.
Academic lecture

Chen, Duan; Zhao, C.M.; Håkanson, R; Samuelson, L.C.; Rehfeld, Jens F.; Friis-Hansen, L. (2003) Regulatory pathways of gastric acid secretion are altered in gastrin- and cholecytokinin-deficient mice. Midt-Norsk Forskningsforum i Gastroenterologi . [Mangler data]; Meråker, Norge. 2003-04-06.
Academic lecture

Chen, Duan; Zhao, C.M.; Wang, X.; Friis-Hansen, L; Waldum, Helge; Halgunset, Jostein; Wadstrøm, T. (2003) Does gastrin play any role in development of gastric cancer or duodenal ulcer after chronic Helicobacter pylori infection?. Proceedings of 11th International conference on ulcer research . [Mangler data]; Croatia. 2003-09-20.
Poster

Chen, Duan; Zhao, Chun-Mei; Friis-Hansen, L; Waldum, Helge; Halgunset, Jostein; Wadstrøm, T. (2003) Chronic Helicobacter pylori infection may result in gastric cancer in hypergastrinemic mice but not in gastrin-deficient mice. International Conference on Applied Genomics . [Mangler data]; Amsterdam, The Netherlands. 2003-10-04.
Poster

Chen, Duan; Zhao, Chun-Mei; Friis-Hansen, L; Waldum, Helge; Halgunset, Jostein; Wadstrøm, T. (2003) Does gastrin play any role in development of gastric cancer or duodenal ulcer after chronic Helicobacter pylori infection?. 11th International Conference on ulcer research . [Mangler data]; Dubrovnik, Croatia. 2003-09-20.
Popular scientific lecture

Chen, Duan; Zhao, Chun-Mei; Håkanson, Rolf; Samuelson, L.C.; Rehfeld, Jens F.; Friis-Hansen, L. (2003) Regulatory pathways of gastric acid secretion are altered in gastrin- and cholecytokinin-deficient mice. Midt-Norsk Forskningsforum i gastroenterologi . [Mangler data]; Meråker, Norge. 2003-04-06.
Academic lecture

Martinsen, Tom Christian; Bakke, I; Chen, Duan; Aamo, T; Zahlsen, Kolbjørn; Waldum, Helge. (2003) Ciprofibrate stimulates the gastrin-producing cell by acting luminally on antral PPARa receptors. Midt-Norsk Forskningsforum i Gastroenterologi . [Mangler data]; Meråker, Norge. 2003-04-06.
Academic lecture

Martinsen, Tom Christian; Bakke, I; Chen, Duan; Waldum, Helge. (2003) Mekanismen for fibrat-indusert hypergastrinemi. Norsk gastroenterologisk forenings 30. årsmøte . [Mangler data]; Lillehammer. 2003-02-09.
Academic lecture

Okabe, S.; Aihara, T.; Chen, Duan. (2003) Role of M3 receptor muscarinic receptor in gastric acid secretion and gastric mucosal integrity. Studies with M3-receptor knockout micd. Proceedings of 11th International cenference on ulcer research . [Mangler data]; Dubrovnik, Croatia. 2003-09-20.

2002

Academic lecture

Chen, Duan; Friis-Hansen, L; Håkanson, R. (2002) Revelation of the complexity of gastric acid secretory mechanism by genetic dissection. BioScience 2005 . BioScience 2005 from genes to systems, SECC; Glasgow. 2002-07-17.
Academic lecture

Chen, Duan; Zhao, Chun-Mei; Wang, X; Friis-Hansen, L; Waldum, Helge; Halgunset, Jostein; Wadstrøm, T. (2002) Disparate effects of chronic Helicobacter pylori infection on parietal cells and ECL cells in wild-type vs gastrin-deficient mice. 18th UICC International Cancer Congress . [Mangler data]; Oslo, Norway. 2002-07-05.
Academic lecture

Chen, Duan; Zhao, Chun-Mei; Wang, X; Friis-Hansen, L; Waldum, Helge; Halgunset, Jostein; Wadstrøm, T. (2002) Host gastrin may determine who will get gastric cancer and who will develop duodenal ulcer after chronic Helicobacter pylori infection. Regpep 2002 . [Mangler data]; Boston, Massachusetts, USA. 2002-09-03.
Academic lecture

Kopin, Alan S.; McBride, E.W.; Ren, Y.; Chen, Duan; Beinborn, M. (2002) A rapid approach to identifying cholecystokinin-2 receptor small molecule ligands with full agonist activity. Regpep 2002 . [Mangler data]; Boston, Massachusetts, USA. 2002-09-03.
Academic lecture

Zhao, Chun-Mei; Wang, Timothy C.; Kopin, Alan S.; Håkanson, Rolf; Chen, Duan. (2002) Mechanism of ECL-cell tumour formation. Studies in rats and transgenic mice. 18th UICC International Cancer Congress . [Mangler data]; Oslo, Norway. 2002-07-05.

2001

Academic lecture

Chen, Duan; Friis-Hansen, L; Wang, X; Zhao, Chun-Mei; Waldum, Helge; Halgunset, Jostein; Wadstrøm, T. (2001) Different effects of chronic Helicobacter pylori infection on parietal and ECL cells between wild type and gastrin-deficient mice. Digestive Disease Week . [Mangler data]; Atlanta, Georgia, USA. 2001-05-23.
Academic lecture

Chen, Duan; Zhao, Chun-Mei; Falkmer, Sture Emil; Waldum, Helge. (2001) Ablation of parietal cells is associated with ECL-cell hyperplasia in transgenic mice with a genetically engineered ablation of their parietal cell lineage. Digestive Disease Week . [Mangler data]; Atlanta, Georgia, USA. 2001-05-23.
Academic lecture

Cui, Guanglin; Syversen, Unni; Zhao, Chun-Mei; Chen, Duan; Waldum, Helge. (2001) Behandling av unge rotter med omeprazol resulterer i redusert beintetthet og redusert vektøkning. Norsk Gastroenterologisk Forenings 28. årsmøte . [Mangler data]; Lillehammer. 2001-02-11.

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Duan Chen

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