Trude Helen Flo

About

Professor in Cell Biology. Heads a research group on host-pathogen interactions, inflammatory responses and cell death - in general and during Mycobacerium tuberculosis infection. Teaching immunology and cell biology.

Curriculum

Professor in Cell Biology at the Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU)
Co-director and Director of CEMIR: Centre of Molecular Inflammation Research, a Centre of Excellence at the Faculty of Medicine, NTNU (2013-2024)
Fulbright Visiting Scholar in Jon Kagan's lab at Boston Children's Hospital /Harvard Medical School, Boston US (2021-2022)
Researcher at Dept. of Cancer Research and Molecular Medicine, NTNU (2004 - 2014)
Associate Professor II in Immunology at Dept. of Laboratory Medicine, NTNU (2011 - 2013)
Post doc in Alan Aderems lab, Institute for Systems Biology, Seattle, USA (2002-2003)
PhD (Dr.Philos) in Immunology/Cell Biology at Dept. of Cancer Research and Molecular Medicine, NTNU (1997-2001)
MSc (sivilingeniør) in Biotechnology at The Norwegian Institute of Technology (NTH, later NTNU, 1991-1995)

2025 - Board member of Svanhild and Arne Musts Foundation for Medical Research
2021 - Member of the Lundbeck Foundation Talent Panel

Research activities and interests

My research is focused on host-pathogen interactions between innate immune cells and pathogens, especially Mycobacterium tuberculosis but also other bacterial and viral pathogens. Infectious diseases still represents a threath to global health and the world is in great need for new medications and vaccines. Our basic research may contribute in revealing new therapeutic or vaccine targets. We have a BSL3 lab with a Leica SP8 confocal microscope where we investigate host-pathogen relations in M. tuberculosis-infected macrophages, HIV and SARS-CoV2 infection and we have established methods for correlative imaging at an ultra-high resolution and in 3D using FIB-SEM together with fluorescence microscopy. Intracellular trafficking, compartmentalized receptor signaling and pathogen-induced host-cell death are investigated in our lab. We recently established protocols for genetic editing of human induced pluripotent stem cells (iPSCs) that we use to generate macrophages, alveolar epithelial cells and a co-culture model to study how cellular cross-talk shapes the inflammatory response and infection outcome.

We have also collaborated with artists - read about how an intestinal bacterium from Bergen and a splinter from the Oseberg viking ship became art!

Publications [PubMed]

Research

My research interest has long been innate immunity, focusing on host responses to pathogens. My early work on Toll-like receptors (TLRs) helped clarify aspects of ligand recognition by TLRs, also because I made one of the first monoclonal Abs against human TLR2 (Flo et al, J. Immunol 2000). During my postdoc in Alan Aderems lab at the Institute for Systems Biology in Seattle, USA, I made the ground-breaking discovery of a novel iron-withholding host defence strategy mediated by lipocalin 2 (or NGAL) (Flo et al., Nature 2004). As a PI, I have been intrigued by how pathogens like mycobacteria and HIV can survive within humans for a lifetime. We made a controversial finding that HIV is detected by TLR8 in T cells and showed that TLR8 ligands are potentially promising for new HIV therapy (Meås et al, Nature Commun 2020). My approach to spatiotemporally dissect host-pathogen interactions using microscopy combined with molecular techniques has led to major discoveries on pathogen recognition, inflammatory signalling, and cell death. We use different microscopy methods including time-lapse and correlative light- and 3D electron microscopy (CLEM) for determining how mycobacteria are sensed within immune cells, and how they evade host defences. Using CLEM, we were the first to image inflammasomes in situ in macrophages and revealed that they can form from M. tuberculosis causing direct plasma membrane damage (Beckwith et al, Nature Commun 2020). Our recent work reveals that glycine’s cytoprotective effect stems from its targeting of NINJ1 (Borges et al, eLife 2022), a newly identified executioner of cell lysis, and that NINJ1 mediates necrosis of M. tuberculosis-infected macrophages (Sætra et al, biorXiv).

Our research group has extensive experience in innate immunity, macrophage- and T cell biology, cutting-edge microscopy, and immunological techniques. We have established infection models in human macrophages (M. tuberculosis, M. avium), epithelial cells (SARS-CoV-2), and mice (UTI/UPEC, M. avium). Moreover, we recently established CRISPR methods for genetically modifying human induced pluripotent stem cells (iPSCs) and a lung-mimetic co-culture model from iPSC-derived macrophages and alveolar epithelial cells for studies of cellular crosstalk.

MYCOVIR research group

C-LUNG: Childrens lung study in Dhulikhel, Nepal

Together with pediatrician Kari Risnes, I run a research project in Dhulikhel, Nepal, aimed at understanding how viral lower respiratory tract infections impact lung health in young children.

Publications

2026

Verwey, Charl; Dongol, Srijana; Shahi, Renu; Islam, Md Shafiqul; Katuwal, Nishan; Haug, Markus; Flo, Trude Helen; Shrestha, Rajeev; Risnes, Kari Ravndal. (2026) Pulmonary Function Testing Using Tidal Breath Flow-Volume Loops in Healthy Children 1–24 Months of Age in Semi-Rural Nepal: Feasibility Study. Pediatric Pulmonology
Academic article

2025

Haug, Markus; Flo, Trude Helen; Rønningstad, Åshild; You, Chanha. (2025) The STING of Death: Uncovering the role of the innate immune receptor STING in human CD4+ T cell death. Norges teknisk-naturvitenskapelige universitet
Master thesis

2024

Mediaas, Sindre Dahl; Haug, Markus; Louet, Claire; Wahl, Sissel Gyrid Freim; Gidon, Alexandre; Flo, Trude Helen. (2024) Metformin improves Mycobacterium avium infection by strengthening macrophage antimicrobial functions. Frontiers in Immunology
Academic article
Sætra, Ragnhild Sofie Ragnhildstveit; Bugge, Marit; Beckwith, Kai Sandvold; Flo, Trude Helen. (2024) Ninjurin 1 and cell death mechanisms in Mycobacterium tuberculosis-infected human macrophages. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis

2023

Kotimoole, Chinmaya Narayana; Antil, Neelam; Kasaragod, Sandeep; Behera, Santosh Kumar; Aravind, Anjana; Reiling, Norbert; Flo, Trude Helen; Prasad, Thottethodi S K. (2023) Development of a Spectral Library for the Discovery of Altered Genomic Events in Mycobacterium avium Associated With Virulence Using Mass Spectrometry-Based Proteogenomic Analysis. Molecular & Cellular Proteomics
Academic article
Kotimoole, Chinmaya Narayana; Ramya, Vadageri Krishnamurthy; Kaur, Parvinder; Reiling, Norbert; Shandil, Radha Krishan; Narayanan, Shridhar; Flo, Trude Helen; Prasad, Thottethodi Subrahmanya. (2023) Discovery of Species-Specific Proteotypic Peptides To Establish a Spectral Library Platform for Identification of Nontuberculosis Mycobacteria from Mass Spectrometry-Based Proteomics. Journal of Proteome Research
Academic article
Nore, Kristin Grotle; Louet, Claire; Bugge, Marit; Gidon, Alexandre; Jørgensen, Marthe Jøntvedt; Jenum, Synne; Riise, Anne Ma Dyrhol-; Tonby, Kristian; Flo, Trude Helen. (2023) The Cyclooxygenase 2 Inhibitor Etoricoxib as Adjunctive Therapy in Tuberculosis Impairs Macrophage Control of Mycobacterial Growth. Journal of Infectious Diseases
Academic article

2022

Røst, Lisa M.; Louet, Claire; Bruheim, Per; Flo, Trude Helen; Gidon, Alexandre. (2022) Pyruvate Supports RET-Dependent Mitochondrial ROS Production to Control Mycobacterium avium Infection in Human Primary Macrophages. Frontiers in Immunology
Academic article
Borges, Jazlyn P.; Sætra, Ragnhild Sofie Ragnhildstveit; Volchuk, Allen; Bugge, Marit; Devant, Pascal; Sporsheim, Bjørnar; Kilburn, Bridget R.; Evavold, Charles L.; Kagan, Jonathan C.; Goldenberg, Neil M.. (2022) Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death. eLIFE
Academic article

2021

Gidon, Alexandre; Louet, Claire; Røst, Lisa M.; Bruheim, Per; Flo, Trude Helen. (2021) The Tumor Necrosis Factor Alpha and Interleukin 6 Auto-paracrine Signaling Loop Controls Mycobacterium avium Infection via Induction of IRF1/IRG1 in Human Primary Macrophages. mBio
Academic article
Bjorkli, Christiana; Louet, Claire; Flo, Trude Helen; Hemler, Mary Elizabeth; Sandvig, Axel; Sandvig, Ioanna. (2021) In Vivo Microdialysis in Mice Captures Changes in Alzheimer´s Disease Cerebrospinal Fluid Biomarkers Consistent with Developing Pathology. Journal of Alzheimer's Disease
Academic article
Rex, D.A.B.; Deepak, K.; Vaid, Neelanchal; Dagamajalu, Shobha; Kandasamy, Richard Kumaran; Flo, Trude Helen; Prasad, Prasad Keshava. (2021) A modular map of Bradykinin-mediated inflammatory signaling network. Journal of cell communication and signaling
Academic article
Klionsky, Daniel J.; Abdel-Aziz, Amal Kamal; Abdelfatah, Sara; Abdellatif, Mahmoud Khaled; Abdoli, Asghar; Abudu, Yakubu Princely; Birgisdottir, Åsa Birna; Bjørkøy, Geir; Calbet, Jose Antonio Lopez; Chica-Balaguera, Nathalia. (2021) Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy
Academic literature review

2020

Bazilchuk, Nancy Reney; Meås, Hany Zakaria; Haug, Markus; Flo, Trude Helen. (2020) Vil lure HIV-virus ut av gjemmestedene. Gemini.no
Popular science article
Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Ullmann, Sindre; Sætra, Ragnhild Sofie Ragnhildstveit; Kim, Hae Lin; Marstad, Anne; Åsberg, Signe Elisabeth; Strand, Trine Aakvik; Haug, Markus; Niederweis, Michael. (2020) Plasma membrane damage causes NLRP3 activation and pyroptosis during Mycobacterium tuberculosis infection. Nature Communications
Academic article
Meås, Hany Zakaria; Haug, Markus; Beckwith, Marianne Sandvold; Louet, Claire; Ryan, Liv; Hu, Zhenyi; Landskron, Johannes; Nordbø, Svein Arne; Tasken, Kjetil; Yin, Hang. (2020) Sensing of HIV-1 by TLR8 activates human T cells and reverses latency. Nature Communications
Academic article
Kannan, Nisha; Haug, Markus; Steigedal, Magnus; Flo, Trude Helen. (2020) Mycobacterium smegmatis Vaccine Vector Elicits CD4+ Th17 and CD8+ Tc17 T Cells With Therapeutic Potential to Infections With Mycobacterium avium. Frontiers in Immunology
Academic article
Flo, Trude Helen; Meås, Hany Zakaria; Damås, Jan Kristian; Haug, Markus. (2020) Forskere: Slik kan vi lure hivviruset til å avsløre seg selv. Aftenposten Viten
Popular science article
Åsberg, Signe Elisabeth; Mediaas, Sindre Dahl; Marstad, Anne; Ryan, Liv; Louet, Claire; Sporsheim, Bjørnar; Beckwith, Kai Sandvold; Underhill, David; Gidon, Alexandre; Flo, Trude Helen. (2020) Antibiotic treatment routes Mycobacterium avium to phagolysosomes without triggering proinflammatory cytokine production in human Mϕs. Journal of Leukocyte Biology
Academic article
Subbannayya, Yashwanth; Haug, Markus; Pinto, Sneha; Mohanty, Varshasnata; Meås, Hany Zakaria; Flo, Trude Helen; Prasad, T. S. Keshava; Kandasamy, Richard Kumaran. (2020) The Proteomic Landscape of Resting and Activated CD4+ T Cells Reveal Insights into Cell Differentiation and Function. International Journal of Molecular Sciences
Academic article

2019

Haug, Markus; Meås, Hany Zakaria; Beckwith, Marianne Sandvold; Louet, Claire; Ryan, Liv; Hu, Z.; Landskron, Johannes; Nordbø, Svein Arne; Tasken, Kjetil; Yin, H. H.. (2019) P1511 - Sensing of HIV-1 nucleic acids by TLR8 in human CD4+ T cells. European Journal of Immunology
Conference abstract
Dragset, Marte Singsås; Ioerger, Thomas R.; Zhang, Yanjia; Mærk, Mali; Ginbot, Zekarias; Sacchettini, James C.; Flo, Trude Helen; Rubin, Eric J; Steigedal, Magnus. (2019) Genome-wide phenotypic profiling identifies and categorizes genes required for mycobacterial low iron fitness. Scientific Reports
Academic article
Dragset, Marte Singsås; Ioerger, Thomas R.; Loevenich, Maja; Haug, Markus; Sivakumar, Niruja; Marstad, Anne; Cardona, Pere-Joan; Klinkenberg, Geir; Rubin, Eric J.; Steigedal, Magnus. (2019) Global assessment of Mycobacterium avium subsp. hominissuis genetic requirement for growth and virulence. mSystems
Academic article
Thorsvik, Silje; Granlund, Atle van Beelen; Svendsen, Tarjei Dahl; Bakke, Ingunn; Røyset, Elin Synnøve; Flo, Trude Helen; Damås, Jan Kristian; Østvik, Ann Elisabet; Bruland, Torunn; Sandvik, Arne Kristian. (2019) Ulcer-associated cell lineage expresses genes involved in regeneration and is hallmarked by high neutrophil gelatinase-associated lipocalin (NGAL) levels. Journal of Pathology
Academic article
Kannan, Nisha; Lai, Yi-Pin; Haug, Markus; Lilleness, Mary Kathleen; Bakke, Siril Skaret; Marstad, Anne; Hov, Håkon; Naustdal, Thor; Afset, Jan Egil; Ioerger, Thomas R.. (2019) Genetic Variation/Evolution and Differential Host Responses Resulting from In-Patient Adaptation of Mycobacterium avium. Infection and Immunity
Academic article

2018

Åsberg, Signe; Flo, Trude Helen; Underhill, David; Gidon, Alexandre. (2018) The Drug, the Bug and the Macrophage: Interactions between antibiotics, mycobacteria and macrophages at the single cell and subcellular level. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Haug, Markus; Brede, Gaute; Håkerud, Monika; Nedberg, Anne Grete Gargul; Gederaas, Odrun Arna; Flo, Trude Helen; Edwards, Victoria Tudor; Selbo, Pål Kristian; Høgset, Anders; Halaas, Øyvind. (2018) Photochemical internalization of peptide antigens provides a novel strategy to realize therapeutic cancer vaccination. Frontiers in Immunology
Academic article
Kannan, Nisha; Steigedal, Magnus; Flo, Trude Helen; Haug, Markus. (2018) Understanding and preventing Mycobacterium avium infections. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Beckwith, Marianne; Flo, Trude Helen; Halaas, Øyvind. (2018) Targeted correlative light and electron microscopy in the study of host-pathogen interactions. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Ørning, Mathias Pontus Andreas; Flo, Trude Helen; Lien, Egil. (2018) A Sugar Rush for Innate Immunity. Cell Host and Microbe
Academic article
Pedersen, Tina Therese; Fenstad, Mona H.; Jakobsen, Bente; Koksvik, Hege; Moksnes, Tone; Wallenius, Marianne; Flo, Trude Helen; Haug, Markus. (2018) Low lipocalin-2 in systemic lupus erythematosus pregnancies- a possible mechanism for loss of tolerance. Annals of the Rheumatic Diseases
Conference abstract

2017

Thorsvik, Silje; Damås, Jan Kristian; Granlund, Atle van Beelen; Flo, Trude Helen; Bergh, Kåre; Østvik, Ann Elisabet; Sandvik, Arne Kristian. (2017) Fecal neutrophil gelatinase-associated lipocalin as a biomarker for inflammatory bowel disease. Journal of Gastroenterology and Hepatology
Academic article
Mildenberger, Jennifer; Johansson, Ida; Sergin, Ismail; Kjøbli, Eli; Damås, Jan Kristian; Razani, Babak; Flo, Trude Helen; Bjørkøy, Geir. (2017) N-3 PUFAs induce inflammatory tolerance by formation of KEAP1-containing SQSTM1/p62-bodies and activation of NFE2L2. Autophagy
Academic article
Awuh, Jane Atesoh; Flo, Trude Helen. (2017) Molecular basis of mycobacterial survival in macrophages. Cellular and Molecular Life Sciences (CMLS)
Academic literature review
Awuh, Jane Atesoh; Flo, Trude Helen. (2017) Erratum to: Molecular basis of mycobacterial survival in macrophages (Cellular and Molecular Life Sciences, (2017), 74, 9, (1625-1648), 10.1007/s00018-016-2422-8). Cellular and Molecular Life Sciences (CMLS)
Corrigendum
Pedersen, Tina Therese; Fenstad, Mona H.; Moksnes, Tone; Wallenius, Marianne; Flo, Trude Helen; Haug, Markus. (2017) Cytokines and lipocalin-2 in pregnant women with rheumatoid arthritis and systemic lupus erythematosus. Annals of the Rheumatic Diseases
Conference abstract
Gidon, Alexandre; Åsberg, Signe; Louet, Claire; Ryan, Liv; Haug, Markus; Flo, Trude Helen. (2017) Persistent mycobacteria evade an antibacterial program mediated by phagolysosomal TLR7/8/MyD88 in human primary macrophages. PLoS Pathogens
Academic article

2016

Waagsbø, Bjørn; Svardal, Asbjørn M.; Ueland, Thor; Landrø, Linn Aina Ysland; Øktedalen, Olav; Berge, Rolf Kristian; Flo, Trude Helen; Aukrust, Pål; Damås, Jan Kristian. (2016) Low levels of short- and medium-chain acylcarnitines in HIV-infected patients. European Journal of Clinical Investigation
Academic article
Ostrop, Jenny; Åsberg, Signe Elisabeth; Flo, Trude Helen; Sørbø, Håvard Gullik. (2016) Characterization of the C-type lectin receptor Mincle in Mycobacterium avium-infected macrophages. Norges teknisk-naturvitenskapelige universitet
Master thesis
Tesfaye, Demo Yemane; Flo, Trude Helen; Ibrahim, Hany; Haug, Markus. (2016) Characterization of Jurkat E6.1 T cell line as a potential model system for primary CD4+ T cells to study the role of TLR8 in HIV infection. Norges teknisk-naturvitenskapelige universitet
Master thesis

2015

Bergstrøm, Bjarte; Aune, Marie Hjelmseth; Awuh, Jane Atesoh; Kojen, June Frengen; Blix, Kjetil Jordahl; Ryan, Liv; Flo, Trude Helen; Mollnes, Tom Eirik; Espevik, Terje; Stenvik, Jørgen. (2015) TLR8 senses Staphylococcus aureus RNA in human primary monocytes and macrophages and induces IFN-β production via a TAK1-IKKβ-IRF5 signaling pathway. Journal of Immunology
Academic article
Dragset, Marte Singsås; Barczak, Amy K.; Kannan, Nisha; Mærk, Mali; Flo, Trude Helen; Valla, Svein; Rubin, Eric J.; Steigedal, Magnus. (2015) Benzoic Acid-Inducible Gene Expression in Mycobacteria. PLOS ONE
Academic article
Buset, Karen Johanne; Kvam, Anne Mari Selven; Nordrum, Ivar Skjåk; Strypet, Hanne; Sylvester, Morten; Ødegården, Mona; Aadahl, Petter; Selvaag, Elisabeth; Flo, Trude Helen. (2015) UNG HELSE.
Exhibition
Beckwith, Marianne; Beckwith, Kai Sandvold; Sikorski, Pawel; Skogaker, Nan Elisabeth Tostrup; Flo, Trude Helen; Halaas, Øyvind. (2015) Seeing a mycobacterium-infected cell in nanoscale 3D: Correlative imaging by light microscopy and FIB/SEM tomography. PLOS ONE
Academic article
Awuh, Jane Atesoh; Haug, Markus; Mildenberger, Jennifer; Marstad, Anne; Chau, Do Ngoc Phuc; Louet, Claire; Stenvik, Jørgen; Steigedal, Magnus; Damås, Jan Kristian; Halaas, Øyvind. (2015) Keap1 regulates inflammatory signaling in Mycobacterium avium-infected human macrophages. Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Academic article

2014

Steigedal, Magnus; Marstad, Anne; Haug, Markus; Damås, Jan Kristian; Strong, Roland K.; Roberts, Pacita L.; Himpsl, Stephanie D.; Stapleton, Ann; Hooton, Thomas M.; Mobley, Harry L.T.. (2014) Lipocalin 2 imparts selective pressure on bacterial growth in the bladder and is elevated in women with urinary tract infection. Journal of Immunology
Academic article

2013

Haug, Markus; Awuh, Jane Atesoh; Steigedal, Magnus; Kojen, June Frengen; Marstad, Anne; Nordrum, Ivar Skjåk; Halaas, Øyvind; Flo, Trude Helen. (2013) Dynamics of immune effector mechanisms during infection with Mycobacterium aviumin C57BL/6 mice. Immunology
Academic article
Østvik, Ann Elisabet; Granlund, Atle Van Beelen; Torp, Sverre Helge; Flatberg, Arnar; Beisvag, Vidar; Waldum, Helge; Flo, Trude Helen; Espevik, Terje; Damås, Jan Kristian; Sandvik, Arne Kristian. (2013) Expression of Toll-like receptor-3 is enhanced in active inflammatory bowel disease and mediates the excessive release of lipocalin 2. Clinical and Experimental Immunology
Academic article

2012

Pathak, Sharad; Awuh, Jane Atesoh; Leversen, Nils Anders; Flo, Trude Helen; Åsjø, Birgitta. (2012) Counting mycobacteria in infected human cells and mouse tissue: a comparison between qPCR and CFU. PLOS ONE
Academic article
Nymo, Ståle Haugset; Ueland, Thor; Askevold, Erik Tandberg; Flo, Trude Helen; Kjekshus, John; Hulthe, Johannes; Wikstrand, John; McMurray, J; Veldhuisen, D J Van; Gullestad, Lars. (2012) The association between neutrophil gelatinase-associated lipocalin and clinical outcome in chronic heart failure: results from CORONA. Journal of Internal Medicine
Academic article
Damås, Jan Kristian; Bækken, Morten; Ueland, Thor; Manner, INGJERD W; Os, Ingrid; Yndestad, Arne; Flo, Trude Helen; Øktedalen, Olav; Aukrust, Pål. (2012) Serum Levels of Neutrophil Gelatinase-Associated Lipocalin Are Associated With Microalbuminuria in HIV-Infected Patients. Journal of Acquired Immune Deficiency Syndromes
Commentary
Damås, Jan Kristian; Øktedalen, Olav; Ueland, Thor; Landrø, Linn Aina Ysland; Barstad, Johannes; Müller, Fredrik; Frøland, Stig Sophus; Flo, Trude Helen; Aukrust, Pål. (2012) Enhanced levels of CCL19 in patients with advanced acquired immune deficiency syndrome (AIDS). Clinical and Experimental Immunology
Academic article

2010

Halaas, Øyvind; Steigedal, Magnus; Haug, Markus; Awuh, Jane Atesoh; Ryan, Liv; Brech, Andreas; Sato, S; Husebye, Harald; Cangelosi, Gerard; Akira, Shizuo. (2010) Intracellular Mycobacterium avium Intersect Transferrin in the Rab11(+) Recycling Endocytic Pathway and Avoid Lipocalin 2 Trafficking to the Lysosomal Pathway. Journal of Infectious Diseases
Academic article
Pukstad, Brita; Ryan, Liv; Flo, Trude Helen; Stenvik, Jørgen; Moseley, Ryan; Harding, Keith; Thomas, David W.; Espevik, Terje. (2010) Non-healing is associated with persistent stimulation of the innate immune response in chronic venous leg ulcers. Journal of dermatological science (Amsterdam)
Academic article

2009

Yndestad, A; Landrø, Linn; Ueland, Thor; Dahl, CP; Flo, Trude Helen; Vinge, Leif Erik; Espevik, Terje; Frøland, Stig S; Husberg, Cathrine; Christensen, Geir. (2009) Increased systemic and myocardial expression of neutrophil gelatinase-associated lipocalin in clinical and experimental heart failure. European Heart Journal
Academic article
Damås, Jan Kristian; Davi, Giovanni; Jensenius, M; Santilli, F; Otterdal, K; Ueland, T; Flo, Trude Helen; Lien, E; Espevik, Terje; Frøland, Stig S. (2009) Relative chemokine and adhesion molecule expression in Mediterranean spotted fever and African tick bite fever. Journal of Infection
Academic article

2008

Landrø, Linn Aina Ysland; Landro, L; Damås, Jan Kristian; Damas, JK; Flo, Trude Helen; Heggelund, L; Ueland, T; Tjønnfjord, Geir Erland; Tjonnfjord, GE; Espevik, Terje. (2008) Decreased serum lipocalin-2 levels in human immunodeficiency virus-infected patients: increase during highly active anti-retroviral therapy. Clinical and Experimental Immunology
Academic article

2004

Heggelund, Lars; Flo, T; Berg, K; Lien, T; Mollnes, TE; Ueland, Thor; Aukrust, Pål; Espevik, T; Frøland, Stig Sophus. (2004) Soluble toll-like receptor 2 in HIV infection: association with disease progression. AIDS (London)
Academic article
Flo, Trude Helen; Smith, KD; Sato, S; Rodriguez, DJ; Holmes, MA; Strong, RK; Akira, S; Aderem, A. (2004) Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron. Nature
Academic article
Heggelund, L; Flo, Trude Helen; Berg, K.; Lien, E; Espevik, Terje. (2004) Soluble toll-like receptor 2 in HIV infection: association with disease progression. AIDS (London)
Academic article

2003

Schjetne, KW; Thompson, KM; Nilsen, Nadra; Flo, Trude Helen; Fleckenstein, B; Iversen, JG; Espevik, Terje; Bogen, B. (2003) Cutting edge: link between innate and adaptive immunity: Toll-like receptor 2 internalizes antigen for presentation to CD4+ T cells and could be an efficient vaccine target. Journal of Immunology
Academic article
Schjetne, KW; Thompson, Keith; Fleckenstein, Burkhard; Aarvak, Tanja; Flo, T. H.; Iversen, Jens Gustav; Espevik, T; Bogen, Bjarne. (2003) Cutting edge: Link between innate and adaptive immunity: toll like receptor 2 (TLR 2) captures antigen for MHC class II presentation to CD4+ T cell responses. Journal of Immunology
Academic article

2002

Dybdahl, Brit; Lien, Egil; Flo, Trude Helen; Espevik, Terje; Sundan, Anders; Wahba, Alexander; Sellevold, Olav F Münter. (2002) Heat Shock Proteins and Endotoxin Combined as a Trigger for Inflammatory Cytokine Release During Cardiopulmonary Bypass: A Possible Third Way? Letter til artikkel. Circulation
Academic article
Flo, Trude Helen; Ryan, Liv; Latz, Eicke; Takeuchi, Osamu; Monks, Brian G.; Lien, Egil; Halaas, Øyvind; Akira, Shizuo; Skjåk-Bræk, Gudmund; Golenbock, Douglas T.. (2002) Involvement of toll-like receptor (TLR) 2 and TLR4 in cell activation by mannuronic acid polymers. Journal of Biological Chemistry
Academic article
Ellingsen, E.A.; Morath, S; Flo, Trude Helen; Schromm, Andra; Hartung, T; Thiemermann, C; Espevik, Terje; Golenbock, Douglas T.; Foster, D; Solberg, R.. (2002) Induction of cytokine production in human T cells and monocytes by highly purified lipoteichoic acid: involvement of Toll-like receptors and CD14. Medical Science Monitor
Academic article
Dybdahl, Brit; Wahba, Alexander; Lien, Egil; Flo, Trude Helen; Waage, Anders; Sellevold, Olav F Münter; Espevik, Terje; Sundan, Anders; Qureshi, Nilofer. (2002) Inflammatory response after open heart surgery: release of heat-shock protein 70 and signaling through toll-like receptor-4. Circulation
Academic article

2001

Wang, J; Warris, A; Ellingsen, E.A.; Jorgensen, P.F.; Flo, Trude Helen; Espevik, Terje; Solberg, R.; Verweij, P.E.; Aasen, A. O.. (2001) Involvement of CD14 and toll-like receptors in activation of human monocytes by Aspergillus fumigatus hyphae. Infection and Immunity
Academic article
Flo, Trude Helen; Halaas, Øyvind; Torp, Sverre Helge; Ryan, Liv; Lien, Egil; Dybdahl, Brit; Sundan, Anders; Espevik, Terje. (2001) Differential expression of Toll-like receptor 2 in human cells. Journal of Leukocyte Biology
Academic article
Flo, Trude Helen; Ryan, Liv; Kilaas, L; Skjåk-Bræk, Gudmund; Ingalls, Robin; Sundan, Anders; Golenbock, D; Espevik, Terje. (2001) The involvement of CD14 and beta2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers. Infection and Immunity
Academic article
Flo, Trude Helen. (2001) Receptors involved in cell activation by defined uronic acid polymers and bacterial components. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis

2000

Skjåk-Bræk, Gudmund; Flo, Trude Helen; Halaas, Øyvind; Espevik, Terje. (2000) Immune stimulating properties of di-equatorially beta(1->4) linked poly-uronides. Proceedings of the Phytochemical Society of Europe
Academic article
Cuzzola, M.; Mancuso, G.; Beninati, C.; Biondo, C.; Genovese, F.; Tomasello, F.; Flo, Trude Helen; Espevik, Terje; Teti, G.. (2000) _B2 integrins are involved in cytokine responses to whole gram-positive bacteria. Journal of Immunology
Academic article
Flo, Trude Helen; Ryan, Liv; Kilaas, Lars; Skjåk-Bræk, Gudmund; Ingalls, Robin R.A; Sundan, Anders; Golenbock, Douglas T.; Espevik, Terje. (2000) Involvement of CD14 and _B2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers. Infection and Immunity
Academic article
Cuzzola, Maria; Mancuso, Guiseppe; Beninati, Concetta; Biondo, Carmelo; Hunolstein, Christina von; Orefici, Graziella; Espevik, Terje; Flo, Trude Helen; Teti, Guisseppe. (2000) Human monocyte receptors involved in tumor necrosis factor responses to group B streptococcal products. Infection and Immunity
Academic article
Flo, T.H.; Ryan, L.; Kilaas, L.; Skjåk-Bræk, Gudmund; Ingalls, R.R.; Sundan, A.; Golenbock, D.T.; Espevik, Terje. (2000) Involvement of CD14 and beta2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers. Infection and Immunity
Academic article
Flo, Trude Helen; Halaas, Øyvind; Lien, Egil; Ryan, Liv; Teti, Guiseppe; Golenbock, Douglas T.; Sundan, Anders; Espevik, Terje. (2000) Human Toll-like Receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide. Journal of Immunology
Academic article

1999

Lien, Egil; Sellati, Timothy J.; Yoshimura, Atsutosi; Flo, Trude Helen; Rawadi, Georges; Finberg, Robert W.; Caroll, J.David; Espevik, Terje; Ingalls, Robin R; Radolf, Justin D.. (1999) Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products. Journal of Biological Chemistry
Academic article

1998

Medvedev, AE; Flo, T; Vogel, SN; Robin, R; Golenbock, DT; Teti, G; Espevik, Terje. (1998) Involvement of CD14 and complement receptors CR3 and CR4 in nuclear factor-kappaB activation and TNF production induced by lipopolysaccharide and group B streptococcal cell walls. Journal of Immunology
Academic article
Berntzen, Gøril; Flo, Trude Helen; Medvedev, Andrei E.; Skjåk-Bræk, Gudmund. (1998) The tumor necrosis factor-inducing potency of lipopolysacharide and uronic acid polymers is increased when they are covalently linked to particles. Clinical and Laboratory Immunology
Academic article
Berntzen, G.; Flo, T; Medvedev, A; Kilaas, L; Skjåk-Bræk, Gudmund; Sundan, A; Espevik, Terje. (1998) The tumor necrosis factor-inducing potency of lipopolysaccharide and uronic acid polymers is increased when they are covalently linked to particles. Clinical and Vaccine Immunology
Academic article

Journal publications

Verwey, Charl; Dongol, Srijana; Shahi, Renu; Islam, Md Shafiqul; Katuwal, Nishan; Haug, Markus; Flo, Trude Helen; Shrestha, Rajeev; Risnes, Kari Ravndal. (2026) Pulmonary Function Testing Using Tidal Breath Flow-Volume Loops in Healthy Children 1–24 Months of Age in Semi-Rural Nepal: Feasibility Study. Pediatric Pulmonology
Academic article
Dybdahl, Brit; Lien, Egil; Flo, Trude Helen; Espevik, Terje; Sundan, Anders; Wahba, Alexander; Sellevold, Olav F Münter. (2002) Heat Shock Proteins and Endotoxin Combined as a Trigger for Inflammatory Cytokine Release During Cardiopulmonary Bypass: A Possible Third Way? Letter til artikkel. Circulation
Academic article
Lien, Egil; Sellati, Timothy J.; Yoshimura, Atsutosi; Flo, Trude Helen; Rawadi, Georges; Finberg, Robert W.; Caroll, J.David; Espevik, Terje; Ingalls, Robin R; Radolf, Justin D.. (1999) Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products. Journal of Biological Chemistry
Academic article
Thorsvik, Silje; Damås, Jan Kristian; Granlund, Atle van Beelen; Flo, Trude Helen; Bergh, Kåre; Østvik, Ann Elisabet; Sandvik, Arne Kristian. (2017) Fecal neutrophil gelatinase-associated lipocalin as a biomarker for inflammatory bowel disease. Journal of Gastroenterology and Hepatology
Academic article
Haug, Markus; Meås, Hany Zakaria; Beckwith, Marianne Sandvold; Louet, Claire; Ryan, Liv; Hu, Z.; Landskron, Johannes; Nordbø, Svein Arne; Tasken, Kjetil; Yin, H. H.. (2019) P1511 - Sensing of HIV-1 nucleic acids by TLR8 in human CD4+ T cells. European Journal of Immunology
Conference abstract
Wang, J; Warris, A; Ellingsen, E.A.; Jorgensen, P.F.; Flo, Trude Helen; Espevik, Terje; Solberg, R.; Verweij, P.E.; Aasen, A. O.. (2001) Involvement of CD14 and toll-like receptors in activation of human monocytes by Aspergillus fumigatus hyphae. Infection and Immunity
Academic article
Flo, Trude Helen; Halaas, Øyvind; Torp, Sverre Helge; Ryan, Liv; Lien, Egil; Dybdahl, Brit; Sundan, Anders; Espevik, Terje. (2001) Differential expression of Toll-like receptor 2 in human cells. Journal of Leukocyte Biology
Academic article
Gidon, Alexandre; Louet, Claire; Røst, Lisa M.; Bruheim, Per; Flo, Trude Helen. (2021) The Tumor Necrosis Factor Alpha and Interleukin 6 Auto-paracrine Signaling Loop Controls Mycobacterium avium Infection via Induction of IRF1/IRG1 in Human Primary Macrophages. mBio
Academic article
Flo, Trude Helen; Ryan, Liv; Kilaas, L; Skjåk-Bræk, Gudmund; Ingalls, Robin; Sundan, Anders; Golenbock, D; Espevik, Terje. (2001) The involvement of CD14 and beta2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers. Infection and Immunity
Academic article
Heggelund, Lars; Flo, T; Berg, K; Lien, T; Mollnes, TE; Ueland, Thor; Aukrust, Pål; Espevik, T; Frøland, Stig Sophus. (2004) Soluble toll-like receptor 2 in HIV infection: association with disease progression. AIDS (London)
Academic article
Haug, Markus; Brede, Gaute; Håkerud, Monika; Nedberg, Anne Grete Gargul; Gederaas, Odrun Arna; Flo, Trude Helen; Edwards, Victoria Tudor; Selbo, Pål Kristian; Høgset, Anders; Halaas, Øyvind. (2018) Photochemical internalization of peptide antigens provides a novel strategy to realize therapeutic cancer vaccination. Frontiers in Immunology
Academic article
Schjetne, KW; Thompson, KM; Nilsen, Nadra; Flo, Trude Helen; Fleckenstein, B; Iversen, JG; Espevik, Terje; Bogen, B. (2003) Cutting edge: link between innate and adaptive immunity: Toll-like receptor 2 internalizes antigen for presentation to CD4+ T cells and could be an efficient vaccine target. Journal of Immunology
Academic article
Halaas, Øyvind; Steigedal, Magnus; Haug, Markus; Awuh, Jane Atesoh; Ryan, Liv; Brech, Andreas; Sato, S; Husebye, Harald; Cangelosi, Gerard; Akira, Shizuo. (2010) Intracellular Mycobacterium avium Intersect Transferrin in the Rab11(+) Recycling Endocytic Pathway and Avoid Lipocalin 2 Trafficking to the Lysosomal Pathway. Journal of Infectious Diseases
Academic article
Skjåk-Bræk, Gudmund; Flo, Trude Helen; Halaas, Øyvind; Espevik, Terje. (2000) Immune stimulating properties of di-equatorially beta(1->4) linked poly-uronides. Proceedings of the Phytochemical Society of Europe
Academic article
Bazilchuk, Nancy Reney; Meås, Hany Zakaria; Haug, Markus; Flo, Trude Helen. (2020) Vil lure HIV-virus ut av gjemmestedene. Gemini.no
Popular science article
Pathak, Sharad; Awuh, Jane Atesoh; Leversen, Nils Anders; Flo, Trude Helen; Åsjø, Birgitta. (2012) Counting mycobacteria in infected human cells and mouse tissue: a comparison between qPCR and CFU. PLOS ONE
Academic article
Nymo, Ståle Haugset; Ueland, Thor; Askevold, Erik Tandberg; Flo, Trude Helen; Kjekshus, John; Hulthe, Johannes; Wikstrand, John; McMurray, J; Veldhuisen, D J Van; Gullestad, Lars. (2012) The association between neutrophil gelatinase-associated lipocalin and clinical outcome in chronic heart failure: results from CORONA. Journal of Internal Medicine
Academic article
Bjorkli, Christiana; Louet, Claire; Flo, Trude Helen; Hemler, Mary Elizabeth; Sandvig, Axel; Sandvig, Ioanna. (2021) In Vivo Microdialysis in Mice Captures Changes in Alzheimer´s Disease Cerebrospinal Fluid Biomarkers Consistent with Developing Pathology. Journal of Alzheimer's Disease
Academic article
Steigedal, Magnus; Marstad, Anne; Haug, Markus; Damås, Jan Kristian; Strong, Roland K.; Roberts, Pacita L.; Himpsl, Stephanie D.; Stapleton, Ann; Hooton, Thomas M.; Mobley, Harry L.T.. (2014) Lipocalin 2 imparts selective pressure on bacterial growth in the bladder and is elevated in women with urinary tract infection. Journal of Immunology
Academic article
Rex, D.A.B.; Deepak, K.; Vaid, Neelanchal; Dagamajalu, Shobha; Kandasamy, Richard Kumaran; Flo, Trude Helen; Prasad, Prasad Keshava. (2021) A modular map of Bradykinin-mediated inflammatory signaling network. Journal of cell communication and signaling
Academic article
Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Ullmann, Sindre; Sætra, Ragnhild Sofie Ragnhildstveit; Kim, Hae Lin; Marstad, Anne; Åsberg, Signe Elisabeth; Strand, Trine Aakvik; Haug, Markus; Niederweis, Michael. (2020) Plasma membrane damage causes NLRP3 activation and pyroptosis during Mycobacterium tuberculosis infection. Nature Communications
Academic article
Dragset, Marte Singsås; Ioerger, Thomas R.; Zhang, Yanjia; Mærk, Mali; Ginbot, Zekarias; Sacchettini, James C.; Flo, Trude Helen; Rubin, Eric J; Steigedal, Magnus. (2019) Genome-wide phenotypic profiling identifies and categorizes genes required for mycobacterial low iron fitness. Scientific Reports
Academic article
Flo, Trude Helen; Ryan, Liv; Latz, Eicke; Takeuchi, Osamu; Monks, Brian G.; Lien, Egil; Halaas, Øyvind; Akira, Shizuo; Skjåk-Bræk, Gudmund; Golenbock, Douglas T.. (2002) Involvement of toll-like receptor (TLR) 2 and TLR4 in cell activation by mannuronic acid polymers. Journal of Biological Chemistry
Academic article
Mediaas, Sindre Dahl; Haug, Markus; Louet, Claire; Wahl, Sissel Gyrid Freim; Gidon, Alexandre; Flo, Trude Helen. (2024) Metformin improves Mycobacterium avium infection by strengthening macrophage antimicrobial functions. Frontiers in Immunology
Academic article
Mildenberger, Jennifer; Johansson, Ida; Sergin, Ismail; Kjøbli, Eli; Damås, Jan Kristian; Razani, Babak; Flo, Trude Helen; Bjørkøy, Geir. (2017) N-3 PUFAs induce inflammatory tolerance by formation of KEAP1-containing SQSTM1/p62-bodies and activation of NFE2L2. Autophagy
Academic article
Awuh, Jane Atesoh; Flo, Trude Helen. (2017) Molecular basis of mycobacterial survival in macrophages. Cellular and Molecular Life Sciences (CMLS)
Academic literature review
Dragset, Marte Singsås; Ioerger, Thomas R.; Loevenich, Maja; Haug, Markus; Sivakumar, Niruja; Marstad, Anne; Cardona, Pere-Joan; Klinkenberg, Geir; Rubin, Eric J.; Steigedal, Magnus. (2019) Global assessment of Mycobacterium avium subsp. hominissuis genetic requirement for growth and virulence. mSystems
Academic article
Kotimoole, Chinmaya Narayana; Antil, Neelam; Kasaragod, Sandeep; Behera, Santosh Kumar; Aravind, Anjana; Reiling, Norbert; Flo, Trude Helen; Prasad, Thottethodi S K. (2023) Development of a Spectral Library for the Discovery of Altered Genomic Events in Mycobacterium avium Associated With Virulence Using Mass Spectrometry-Based Proteogenomic Analysis. Molecular & Cellular Proteomics
Academic article
Bergstrøm, Bjarte; Aune, Marie Hjelmseth; Awuh, Jane Atesoh; Kojen, June Frengen; Blix, Kjetil Jordahl; Ryan, Liv; Flo, Trude Helen; Mollnes, Tom Eirik; Espevik, Terje; Stenvik, Jørgen. (2015) TLR8 senses Staphylococcus aureus RNA in human primary monocytes and macrophages and induces IFN-β production via a TAK1-IKKβ-IRF5 signaling pathway. Journal of Immunology
Academic article
Medvedev, AE; Flo, T; Vogel, SN; Robin, R; Golenbock, DT; Teti, G; Espevik, Terje. (1998) Involvement of CD14 and complement receptors CR3 and CR4 in nuclear factor-kappaB activation and TNF production induced by lipopolysaccharide and group B streptococcal cell walls. Journal of Immunology
Academic article
Cuzzola, M.; Mancuso, G.; Beninati, C.; Biondo, C.; Genovese, F.; Tomasello, F.; Flo, Trude Helen; Espevik, Terje; Teti, G.. (2000) _B2 integrins are involved in cytokine responses to whole gram-positive bacteria. Journal of Immunology
Academic article
Ørning, Mathias Pontus Andreas; Flo, Trude Helen; Lien, Egil. (2018) A Sugar Rush for Innate Immunity. Cell Host and Microbe
Academic article
Flo, Trude Helen; Ryan, Liv; Kilaas, Lars; Skjåk-Bræk, Gudmund; Ingalls, Robin R.A; Sundan, Anders; Golenbock, Douglas T.; Espevik, Terje. (2000) Involvement of CD14 and _B2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers. Infection and Immunity
Academic article
Cuzzola, Maria; Mancuso, Guiseppe; Beninati, Concetta; Biondo, Carmelo; Hunolstein, Christina von; Orefici, Graziella; Espevik, Terje; Flo, Trude Helen; Teti, Guisseppe. (2000) Human monocyte receptors involved in tumor necrosis factor responses to group B streptococcal products. Infection and Immunity
Academic article
Meås, Hany Zakaria; Haug, Markus; Beckwith, Marianne Sandvold; Louet, Claire; Ryan, Liv; Hu, Zhenyi; Landskron, Johannes; Nordbø, Svein Arne; Tasken, Kjetil; Yin, Hang. (2020) Sensing of HIV-1 by TLR8 activates human T cells and reverses latency. Nature Communications
Academic article
Kannan, Nisha; Haug, Markus; Steigedal, Magnus; Flo, Trude Helen. (2020) Mycobacterium smegmatis Vaccine Vector Elicits CD4+ Th17 and CD8+ Tc17 T Cells With Therapeutic Potential to Infections With Mycobacterium avium. Frontiers in Immunology
Academic article
Kotimoole, Chinmaya Narayana; Ramya, Vadageri Krishnamurthy; Kaur, Parvinder; Reiling, Norbert; Shandil, Radha Krishan; Narayanan, Shridhar; Flo, Trude Helen; Prasad, Thottethodi Subrahmanya. (2023) Discovery of Species-Specific Proteotypic Peptides To Establish a Spectral Library Platform for Identification of Nontuberculosis Mycobacteria from Mass Spectrometry-Based Proteomics. Journal of Proteome Research
Academic article
Dragset, Marte Singsås; Barczak, Amy K.; Kannan, Nisha; Mærk, Mali; Flo, Trude Helen; Valla, Svein; Rubin, Eric J.; Steigedal, Magnus. (2015) Benzoic Acid-Inducible Gene Expression in Mycobacteria. PLOS ONE
Academic article
Waagsbø, Bjørn; Svardal, Asbjørn M.; Ueland, Thor; Landrø, Linn Aina Ysland; Øktedalen, Olav; Berge, Rolf Kristian; Flo, Trude Helen; Aukrust, Pål; Damås, Jan Kristian. (2016) Low levels of short- and medium-chain acylcarnitines in HIV-infected patients. European Journal of Clinical Investigation
Academic article
Pedersen, Tina Therese; Fenstad, Mona H.; Jakobsen, Bente; Koksvik, Hege; Moksnes, Tone; Wallenius, Marianne; Flo, Trude Helen; Haug, Markus. (2018) Low lipocalin-2 in systemic lupus erythematosus pregnancies- a possible mechanism for loss of tolerance. Annals of the Rheumatic Diseases
Conference abstract
Yndestad, A; Landrø, Linn; Ueland, Thor; Dahl, CP; Flo, Trude Helen; Vinge, Leif Erik; Espevik, Terje; Frøland, Stig S; Husberg, Cathrine; Christensen, Geir. (2009) Increased systemic and myocardial expression of neutrophil gelatinase-associated lipocalin in clinical and experimental heart failure. European Heart Journal
Academic article
Landrø, Linn Aina Ysland; Landro, L; Damås, Jan Kristian; Damas, JK; Flo, Trude Helen; Heggelund, L; Ueland, T; Tjønnfjord, Geir Erland; Tjonnfjord, GE; Espevik, Terje. (2008) Decreased serum lipocalin-2 levels in human immunodeficiency virus-infected patients: increase during highly active anti-retroviral therapy. Clinical and Experimental Immunology
Academic article
Awuh, Jane Atesoh; Flo, Trude Helen. (2017) Erratum to: Molecular basis of mycobacterial survival in macrophages (Cellular and Molecular Life Sciences, (2017), 74, 9, (1625-1648), 10.1007/s00018-016-2422-8). Cellular and Molecular Life Sciences (CMLS)
Corrigendum
Berntzen, Gøril; Flo, Trude Helen; Medvedev, Andrei E.; Skjåk-Bræk, Gudmund. (1998) The tumor necrosis factor-inducing potency of lipopolysacharide and uronic acid polymers is increased when they are covalently linked to particles. Clinical and Laboratory Immunology
Academic article
Berntzen, G.; Flo, T; Medvedev, A; Kilaas, L; Skjåk-Bræk, Gudmund; Sundan, A; Espevik, Terje. (1998) The tumor necrosis factor-inducing potency of lipopolysaccharide and uronic acid polymers is increased when they are covalently linked to particles. Clinical and Vaccine Immunology
Academic article
Flo, Trude Helen; Smith, KD; Sato, S; Rodriguez, DJ; Holmes, MA; Strong, RK; Akira, S; Aderem, A. (2004) Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron. Nature
Academic article
Pukstad, Brita; Ryan, Liv; Flo, Trude Helen; Stenvik, Jørgen; Moseley, Ryan; Harding, Keith; Thomas, David W.; Espevik, Terje. (2010) Non-healing is associated with persistent stimulation of the innate immune response in chronic venous leg ulcers. Journal of dermatological science (Amsterdam)
Academic article
Beckwith, Marianne; Beckwith, Kai Sandvold; Sikorski, Pawel; Skogaker, Nan Elisabeth Tostrup; Flo, Trude Helen; Halaas, Øyvind. (2015) Seeing a mycobacterium-infected cell in nanoscale 3D: Correlative imaging by light microscopy and FIB/SEM tomography. PLOS ONE
Academic article
Heggelund, L; Flo, Trude Helen; Berg, K.; Lien, E; Espevik, Terje. (2004) Soluble toll-like receptor 2 in HIV infection: association with disease progression. AIDS (London)
Academic article
Flo, T.H.; Ryan, L.; Kilaas, L.; Skjåk-Bræk, Gudmund; Ingalls, R.R.; Sundan, A.; Golenbock, D.T.; Espevik, Terje. (2000) Involvement of CD14 and beta2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers. Infection and Immunity
Academic article
Haug, Markus; Awuh, Jane Atesoh; Steigedal, Magnus; Kojen, June Frengen; Marstad, Anne; Nordrum, Ivar Skjåk; Halaas, Øyvind; Flo, Trude Helen. (2013) Dynamics of immune effector mechanisms during infection with Mycobacterium aviumin C57BL/6 mice. Immunology
Academic article
Flo, Trude Helen; Meås, Hany Zakaria; Damås, Jan Kristian; Haug, Markus. (2020) Forskere: Slik kan vi lure hivviruset til å avsløre seg selv. Aftenposten Viten
Popular science article
Åsberg, Signe Elisabeth; Mediaas, Sindre Dahl; Marstad, Anne; Ryan, Liv; Louet, Claire; Sporsheim, Bjørnar; Beckwith, Kai Sandvold; Underhill, David; Gidon, Alexandre; Flo, Trude Helen. (2020) Antibiotic treatment routes Mycobacterium avium to phagolysosomes without triggering proinflammatory cytokine production in human Mϕs. Journal of Leukocyte Biology
Academic article
Thorsvik, Silje; Granlund, Atle van Beelen; Svendsen, Tarjei Dahl; Bakke, Ingunn; Røyset, Elin Synnøve; Flo, Trude Helen; Damås, Jan Kristian; Østvik, Ann Elisabet; Bruland, Torunn; Sandvik, Arne Kristian. (2019) Ulcer-associated cell lineage expresses genes involved in regeneration and is hallmarked by high neutrophil gelatinase-associated lipocalin (NGAL) levels. Journal of Pathology
Academic article
Kannan, Nisha; Lai, Yi-Pin; Haug, Markus; Lilleness, Mary Kathleen; Bakke, Siril Skaret; Marstad, Anne; Hov, Håkon; Naustdal, Thor; Afset, Jan Egil; Ioerger, Thomas R.. (2019) Genetic Variation/Evolution and Differential Host Responses Resulting from In-Patient Adaptation of Mycobacterium avium. Infection and Immunity
Academic article
Pedersen, Tina Therese; Fenstad, Mona H.; Moksnes, Tone; Wallenius, Marianne; Flo, Trude Helen; Haug, Markus. (2017) Cytokines and lipocalin-2 in pregnant women with rheumatoid arthritis and systemic lupus erythematosus. Annals of the Rheumatic Diseases
Conference abstract
Flo, Trude Helen; Halaas, Øyvind; Lien, Egil; Ryan, Liv; Teti, Guiseppe; Golenbock, Douglas T.; Sundan, Anders; Espevik, Terje. (2000) Human Toll-like Receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide. Journal of Immunology
Academic article
Røst, Lisa M.; Louet, Claire; Bruheim, Per; Flo, Trude Helen; Gidon, Alexandre. (2022) Pyruvate Supports RET-Dependent Mitochondrial ROS Production to Control Mycobacterium avium Infection in Human Primary Macrophages. Frontiers in Immunology
Academic article
Borges, Jazlyn P.; Sætra, Ragnhild Sofie Ragnhildstveit; Volchuk, Allen; Bugge, Marit; Devant, Pascal; Sporsheim, Bjørnar; Kilburn, Bridget R.; Evavold, Charles L.; Kagan, Jonathan C.; Goldenberg, Neil M.. (2022) Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death. eLIFE
Academic article
Awuh, Jane Atesoh; Haug, Markus; Mildenberger, Jennifer; Marstad, Anne; Chau, Do Ngoc Phuc; Louet, Claire; Stenvik, Jørgen; Steigedal, Magnus; Damås, Jan Kristian; Halaas, Øyvind. (2015) Keap1 regulates inflammatory signaling in Mycobacterium avium-infected human macrophages. Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Academic article
Damås, Jan Kristian; Bækken, Morten; Ueland, Thor; Manner, INGJERD W; Os, Ingrid; Yndestad, Arne; Flo, Trude Helen; Øktedalen, Olav; Aukrust, Pål. (2012) Serum Levels of Neutrophil Gelatinase-Associated Lipocalin Are Associated With Microalbuminuria in HIV-Infected Patients. Journal of Acquired Immune Deficiency Syndromes
Commentary
Gidon, Alexandre; Åsberg, Signe; Louet, Claire; Ryan, Liv; Haug, Markus; Flo, Trude Helen. (2017) Persistent mycobacteria evade an antibacterial program mediated by phagolysosomal TLR7/8/MyD88 in human primary macrophages. PLoS Pathogens
Academic article
Klionsky, Daniel J.; Abdel-Aziz, Amal Kamal; Abdelfatah, Sara; Abdellatif, Mahmoud Khaled; Abdoli, Asghar; Abudu, Yakubu Princely; Birgisdottir, Åsa Birna; Bjørkøy, Geir; Calbet, Jose Antonio Lopez; Chica-Balaguera, Nathalia. (2021) Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy
Academic literature review
Damås, Jan Kristian; Davi, Giovanni; Jensenius, M; Santilli, F; Otterdal, K; Ueland, T; Flo, Trude Helen; Lien, E; Espevik, Terje; Frøland, Stig S. (2009) Relative chemokine and adhesion molecule expression in Mediterranean spotted fever and African tick bite fever. Journal of Infection
Academic article
Damås, Jan Kristian; Øktedalen, Olav; Ueland, Thor; Landrø, Linn Aina Ysland; Barstad, Johannes; Müller, Fredrik; Frøland, Stig Sophus; Flo, Trude Helen; Aukrust, Pål. (2012) Enhanced levels of CCL19 in patients with advanced acquired immune deficiency syndrome (AIDS). Clinical and Experimental Immunology
Academic article
Schjetne, KW; Thompson, Keith; Fleckenstein, Burkhard; Aarvak, Tanja; Flo, T. H.; Iversen, Jens Gustav; Espevik, T; Bogen, Bjarne. (2003) Cutting edge: Link between innate and adaptive immunity: toll like receptor 2 (TLR 2) captures antigen for MHC class II presentation to CD4+ T cell responses. Journal of Immunology
Academic article
Østvik, Ann Elisabet; Granlund, Atle Van Beelen; Torp, Sverre Helge; Flatberg, Arnar; Beisvag, Vidar; Waldum, Helge; Flo, Trude Helen; Espevik, Terje; Damås, Jan Kristian; Sandvik, Arne Kristian. (2013) Expression of Toll-like receptor-3 is enhanced in active inflammatory bowel disease and mediates the excessive release of lipocalin 2. Clinical and Experimental Immunology
Academic article
Subbannayya, Yashwanth; Haug, Markus; Pinto, Sneha; Mohanty, Varshasnata; Meås, Hany Zakaria; Flo, Trude Helen; Prasad, T. S. Keshava; Kandasamy, Richard Kumaran. (2020) The Proteomic Landscape of Resting and Activated CD4+ T Cells Reveal Insights into Cell Differentiation and Function. International Journal of Molecular Sciences
Academic article
Ellingsen, E.A.; Morath, S; Flo, Trude Helen; Schromm, Andra; Hartung, T; Thiemermann, C; Espevik, Terje; Golenbock, Douglas T.; Foster, D; Solberg, R.. (2002) Induction of cytokine production in human T cells and monocytes by highly purified lipoteichoic acid: involvement of Toll-like receptors and CD14. Medical Science Monitor
Academic article
Dybdahl, Brit; Wahba, Alexander; Lien, Egil; Flo, Trude Helen; Waage, Anders; Sellevold, Olav F Münter; Espevik, Terje; Sundan, Anders; Qureshi, Nilofer. (2002) Inflammatory response after open heart surgery: release of heat-shock protein 70 and signaling through toll-like receptor-4. Circulation
Academic article
Nore, Kristin Grotle; Louet, Claire; Bugge, Marit; Gidon, Alexandre; Jørgensen, Marthe Jøntvedt; Jenum, Synne; Riise, Anne Ma Dyrhol-; Tonby, Kristian; Flo, Trude Helen. (2023) The Cyclooxygenase 2 Inhibitor Etoricoxib as Adjunctive Therapy in Tuberculosis Impairs Macrophage Control of Mycobacterial Growth. Journal of Infectious Diseases
Academic article

Artistic productions

Buset, Karen Johanne; Kvam, Anne Mari Selven; Nordrum, Ivar Skjåk; Strypet, Hanne; Sylvester, Morten; Ødegården, Mona; Aadahl, Petter; Selvaag, Elisabeth; Flo, Trude Helen. (2015) UNG HELSE.
Exhibition

Student thesis or dissertation

Haug, Markus; Flo, Trude Helen; Rønningstad, Åshild; You, Chanha. (2025) The STING of Death: Uncovering the role of the innate immune receptor STING in human CD4+ T cell death. Norges teknisk-naturvitenskapelige universitet
Master thesis
Åsberg, Signe; Flo, Trude Helen; Underhill, David; Gidon, Alexandre. (2018) The Drug, the Bug and the Macrophage: Interactions between antibiotics, mycobacteria and macrophages at the single cell and subcellular level. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Kannan, Nisha; Steigedal, Magnus; Flo, Trude Helen; Haug, Markus. (2018) Understanding and preventing Mycobacterium avium infections. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Beckwith, Marianne; Flo, Trude Helen; Halaas, Øyvind. (2018) Targeted correlative light and electron microscopy in the study of host-pathogen interactions. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Sætra, Ragnhild Sofie Ragnhildstveit; Bugge, Marit; Beckwith, Kai Sandvold; Flo, Trude Helen. (2024) Ninjurin 1 and cell death mechanisms in Mycobacterium tuberculosis-infected human macrophages. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Ostrop, Jenny; Åsberg, Signe Elisabeth; Flo, Trude Helen; Sørbø, Håvard Gullik. (2016) Characterization of the C-type lectin receptor Mincle in Mycobacterium avium-infected macrophages. Norges teknisk-naturvitenskapelige universitet
Master thesis
Tesfaye, Demo Yemane; Flo, Trude Helen; Ibrahim, Hany; Haug, Markus. (2016) Characterization of Jurkat E6.1 T cell line as a potential model system for primary CD4+ T cells to study the role of TLR8 in HIV infection. Norges teknisk-naturvitenskapelige universitet
Master thesis
Flo, Trude Helen. (2001) Receptors involved in cell activation by defined uronic acid polymers and bacterial components. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis

Teaching

I teach Cell Biology and Immunology to Medical Students, MSc students and PhD students at NTNU

Supervision

PhD supervision:

Sindre Dahl Mediaas, MD from NTNU

Niruja Sivakumar, MD from NTNU

Charlotte Årseth, MSc from NTNU Nanotechnology

Mathilde Hansen, MSc from NTNU Molecular Medicine

Clement Lacour, MSc from University of Geneva

Nishan Katuwal, MSc from NTNU Biotechnology

Outreach

2025

Conference poster

Kristensen, Stine; Årseth, Charlotte; Ryan, Liv; Ullmann, Sindre; Lambris, John D.; Mollnes, Tom Eirik; Flo, Trude Helen; Husebye, Harald; Espevik, Terje. (2025) Exploring the role of intracellular C3 in activation of the NLRP3 inflammasome in human macrophages. International Complement Workshop 2025
Other presentation

Hansen, Mathilde; Sætra, Ragnhild Sofie Ragnhildstveit; Bugge, Marit; Flo, Trude Helen. (2025) Exploring NINJ1 in Mtb-induced cell death using genetically modified induced pluripotent stem cell (iPSC)-derived macrophages. NBS contact meeting 2025
Conference lecture

Årseth, Charlotte; Kristensen, Stine; Yurchenko, Maria; Ryan, Liv; Rasheed, Kashif; Ullmann, Sindre; Husebye, Harald; Espevik, Terje; Flo, Trude Helen. (2025) Intracellular and cell autonomous C3 in IRF3 signaling in macrophages. International Complement Workshop 2025
Conference poster

Rønningstad, Åshild; Bugge, Marit; Ryan, Liv; Flo, Trude Helen; Haug, Markus. (2025) The role of the cGAS-STING pathway in primary human CD4+ T cells. Norwegian Bioscience Society; 60th Contact Meeting

2024

Conference poster

Kristensen, Stine; Årseth, Charlotte; Ryan, Liv; Lambris, John D.; Flo, Trude Helen; Mollnes, Tom Eirik; Husebye, Harald; Espevik, Terje. (2024) Decoding the intracellular complement system in human macrophages. TOLL Conference 2024
Conference lecture

Flo, Trude Helen; Sætra, Ragnhild Sofie Ragnhildstveit; Bugge, Marit; Beckwith, Kai Sandvold; Hansen, Mathilde; Fjellvær, Ida; Lacour, Clement Edgar Marius; Marstad, Anne; Nonstad, Unni; Devant, Pascal. (2024) M. tuberculosis induced cell death and a new macrophage – alveolar epithelial cell co-culture model. EMBO|EMBL Symposium: Innate immunity in host-pathogen interactions
Conference lecture

Flo, Trude Helen; Sætra, Ragnhild Sofie Ragnhildstveit; Beckwith, Kai Sandvold; Marstad, Anne; Nonstad, Unni; Hansen, Mathilde; Bugge, Marit; Kappelhoff, Shirin. (2024) Control of mycobacterial infection by inflammasomes. EMBO workshop: The Inflammasomes-2024
Conference lecture

Sætra, Ragnhild Sofie Ragnhildstveit; Bugge, Marit; Marstad, Anne; Beckwith, Kai Sandvold; Flo, Trude Helen. (2024) Elucidating the role of NINJ1 in Mycobacterium tuberculosis-infected macrophages. TOLL Conference 2024
Conference lecture

Haug, Markus; Dyrli, Ole Thomas; Meås, Hany Zakaria; Slørdal, Ingrid; Damås, Jan Kristian; Flo, Trude Helen. (2024) TLR8 agonists as HIV latency reversing agents. 59th NBS Contact meering 2024

2023

Conference poster

Anthonsen, Marit Walbye; Spahn, Alix Saskia; Boyartchuk, Victor; Rian, Kristin; Flo, Trude Helen. (2023) Exploring antiviral effects of itaconate, its isomer citraconate and derivate 4-octyl itaconate in human metapneumovirus-infected macrophages. Viruses in health and disease
Conference poster

Anthonsen, Marit Walbye; Spahn, Alix Saskia; Flo, Trude Helen; Rian, Kristin; Boyartchuk, Victor. (2023) Exploring antiviral effects of itaconate, its isomer citraconate and derivate 4-octyl itaconate in human metapneumovirus-infected macrophages. Viruses in health and disease
Conference poster

Sætra, Ragnhild Sofie Ragnhildstveit; Borges, Jazlyn P.; Volchuk, Allen; Bugge, Marit; Devant, Pascal; Marstad, Anne; Sporsheim, Bjørnar; Kilburn, Bridget R.; Evavold, Charles L.; Kagan, Jonathan C.. (2023) NINJ1 oligomerization dynamics. 18th International Conference on Innate Immunity
Conference lecture

Sivakumar, Niruja; Dragset, Marte Singsås; Marstad, Anne; Flo, Trude Helen. (2023) A novel, multifunctional target in pathogenic mycobacteria. 33rd European Congress of Clinical Microbiology and Infectious Diseases
Conference poster

Sivakumar, Niruja; Dragset, Marte Singsås; Marstad, Anne; Flo, Trude Helen. (2023) MFS1:A conserved virulence target in pathogenic mycobacteria. Tuberculosis Drug Discovery and Development
Conference lecture

Flo, Trude Helen; Gidon, Alexandre; Mediaas, Sindre Dahl; Bugge, Marit. (2023) Spatiotemporal studies of host responses to mycobacteria in macrophages. 178th Nobel Symposium in Chemistry Tuberculosis and antibiotic resistance - from basic drug discovery to clinic
Lecture

Flo, Trude Helen. (2023) Infeksjon og vaksine. NTNU pensjonistforening
Conference lecture

Flo, Trude Helen. (2023) CEMIR - a Centre of Excellence in Molecular Inflammation Research. Department seminar series

2022

Conference lecture

Dragset, Marte Singsås; Selvik, Linn-Karina M.; Flo, Trude Helen; Steigedal, Magnus; Strand, Trine Aakvik; Ullmann, Sindre; Olsen, Lene Christin; Ioerger, Thomas R.; Rubin, Eric J; Baranowski, Catherine. (2022) The role of protease BlaR in mycobacterial low iron growth and virulence. Boston TB meeting
Interview

Flem, Sofie Svanes; Spurkland, Anne; Flo, Trude Helen. (2022) Norsk Facebook-post om korona gikk viralt – men påstanden er feil.
Conference poster

Fjellvær, Ida; Bugge, Marit; Flo, Trude Helen. (2022) Ex vivo lung model to elucidate host-pathogen interactions in Tuberculosis. IBA Annual Meeting
Conference lecture

Flo, Trude Helen; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Sætra, Ragnhild Sofie Ragnhildstveit; Ullmann, Sindre; Bugge, Marit. (2022) Host-cell killing by Mycobacterium tuberculosis. Invited talk
Conference lecture

Flo, Trude Helen; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Sætra, Ragnhild Sofie Ragnhildstveit; Ullmann, Sindre; Bugge, Marit. (2022) The inner life of a mycobacterium-infected macrophage. Invited talk
Conference lecture

Flo, Trude Helen; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Sætra, Ragnhild Sofie Ragnhildstveit; Ullmann, Sindre; Bugge, Marit. (2022) The Inner Life of Mycobacterium Infected Macrophages. Gordon Research Conference on Lysosomes and Endocytosis 2022: Physiological Adaptations of the Endo-Lysosomal System
Conference lecture

Flo, Trude Helen; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Bugge, Marit; Sætra, Ragnhild Sofie Ragnhildstveit; Ullmann, Sindre. (2022) The inner life of a mycobacterium-infected macrophage. NIAID Invited talk
Conference lecture

Flo, Trude Helen; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Gidon, Alexandre; Mediaas, Sindre Dahl; Sætra, Ragnhild Sofie Ragnhildstveit; Bugge, Marit; Ullmann, Sindre; Åsberg, Signe Elisabeth. (2022) Spatiotemporal Relations of Mycobacteria and Human Macrophages. Department seminar series
Conference lecture

Dragset, Marte Singsås; Selvik, Linn-Karina M.; Flo, Trude Helen; Steigedal, Magnus; Strand, Trine Aakvik; Ullmann, Sindre; Olsen, Lene Christin; Ioerger, Thomas R.; Rubin, Eric J; Wakanayashi, Shoko. (2022) Disarm virulence and reduce resistance - in one go? Novel potential targets against tuberculosis. Norwegian Consortium for Microbial Genomics Meeting 2022

2021

Conference lecture

Flo, Trude Helen; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Gidon, Alexandre; Ullmann, Sindre; Sætra, Ragnhild Sofie Ragnhildstveit; Bugge, Marit. (2021) Mycobacterium tuberculosis infection in human macrophages. Department seminar series
Conference lecture

Sætra, Ragnhild Sofie Ragnhildstveit; Bugge, Marit; Marstad, Anne; Flo, Trude Helen. (2021) MOLECULAR MECHANISMS IN MYCOBACTERIUM TUBERCULOSIS-INFECTED MACROPHAGES. IBA Annual Meeting 2021
Interview

Flo, Trude Helen; Olsen, Emilie Sofie. (2021) Slik fungerer koronavaksinen: - Må en lokal betennelse til for at vaksinen skal virke.
Conference lecture

Flo, Trude Helen. (2021) M. tuberculosis membrane damage and killing of host macrophages. IMB day and IMB conference 2021
Conference lecture

Flo, Trude Helen. (2021) Mycobacterium infection in human macrophages. x
Conference lecture

Flo, Trude Helen. (2021) Cell death from membrane damage during Mtb-infection of human macrophage. Cell death symposium
Conference lecture

Flo, Trude Helen. (2021) Killing of host macrophages by Mycobacterium tuberculosis. Invited talk
Conference lecture

Sivakumar, Niruja; Dragset, Marte Singsås; Haug, Markus; Marstad, Anne; Cardona, Pere Joan; Flo, Trude Helen. (2021) A novel, multifunctional target in mycobacterial drug discovery. IBA Annual Meeting

2020

Lecture

Flo, Trude Helen. (2020) Vaksiner - myter og fakta. Seminarserie
Conference poster

Beckwith, Marianne Sandvold; Beckwith, Kai Sandvold; Ullmann, Sindre; Sætra, Ragnhild Sofie Ragnhildstveit; Marstad, Anne; Kim, Haelin; Åsberg, Signe Elisabeth; Strand, Trine Aakvik; Haug, Markus; Niederweis, Michael. (2020) Plasma membrane damage causes NLRP3 activation and pyroptosis during Mycobacterium tuberculosis infection. Keystone Symposium Tuberculosis
Interview

Flo, Trude Helen. (2020) Ny kunnskap om tuberkulosebakterien.
Feature article

Meås, Hany Zakaria; Haug, Markus; Flo, Trude Helen. (2020) A newly discovered mechanism allows the immune system to detect and respond to HIV.
Feature article

Haug, Markus; Meås, Hany Zakaria; Flo, Trude Helen. (2020) Wie man das HI-Virus aufscheucht.
Feature article

Meås, Hany Zakaria; Haug, Markus; Flo, Trude Helen. (2020) Smoking dormant HIV virus out into the open to develop a cure.
Feature article

Haug, Markus; Meås, Hany Zakaria; Flo, Trude Helen. (2020) Smoking HIV out of dormancy.
Conference poster

Sætra, Ragnhild Sofie Ragnhildstveit; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Ullmann, Sindre; Kim, Haelin; Marstad, Anne; Åsberg, Signe Elisabeth; Strand, Trine Aakvik; Flo, Trude Helen. (2020) Mechanisms in human macrophages infected with Mycobacterium tuberculosis. IBA Annual meeting
Conference lecture

Flo, Trude Helen; Gidon, Alexandre; Mediaas, Sindre Dahl; Dragset, Marte Singsås. (2020) AMR in mycobacterial infections and the search for new treatments. AMR-BRIDGE workshop «The need for new antibiotics»
Interview

Ness, Kaja Kristin; Flo, Trude Helen. (2020) Nye funn: Slik dreper tuberkulosebakteriene.
Interview

Midling, Anne Sliper; Flo, Trude Helen. (2020) Verdenspremiere på døden i en celle med tuberkulose World film premiere: watch cell infected with tuberculosis die.
Conference lecture

Mediaas, Sindre Dahl; Gidon, Alexandre; Haug, Markus; Flo, Trude Helen. (2020) THE EFFECT OF HOST-DIRECTED THERAPY ON INTRANASAL MYCOBACTERIUM AVIUM INFECTION. Annual IBA meeting 2020

2019

Conference lecture

Haug, Markus; Meås, Hany Zakaria; Beckwith, Marianne Sandvold; Louet, Claire; Ryan, Liv; Hu, Z.; Landskron, Johannes; Nordbø, Svein Arne; Tasken, Kjetil; Yin, H. H.. (2019) Sensing of HIV-1 by TLR8 in human CD4+ T cells. 45th Annual Meeting of the Scandinavian Society for Immunology (SSI)
Interview

Flo, Trude Helen; Espevik, Terje. (2019) Betennelse – et tveegget sverd for helse og sykdom.
Conference lecture

Flo, Trude Helen; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Ullmann, Sindre; Sætra, Ragnhild Sofie Ragnhildstveit; Strand, Trine Aakvik; Marstad, Anne; Åsberg, Signe; Stenmark, Harald. (2019) Balancing life and death in mycobacterium-infected macrophages. 2nd International conference on molecular mechanisms of inflammation
Lecture

Flo, Trude Helen. (2019) Nye angrepspunkt hos mykobakterier og vert for antibiotikabehandling og immunterapi ved tuberkulose. Verdens tuberkulosedag
Conference lecture

Flo, Trude Helen; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Ullmann, Sindre; Sætra, Ragnhild Sofie Ragnhildstveit; Marstad, Anne; Strand, Trine Aakvik; Stenmark, Harald; Åsberg, Signe. (2019) Single-cell dynamics of NLRP3 inflammasome activation and pyroptosis during Mycobacterium tuberculosis infection of human macrophages. IUIS2019 17th International Congress of Immunology
Conference poster

Ullmann, Sindre; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Åsberg, Signe; Strand, Trine Aakvik; Flo, Trude Helen. (2019) Single-cell Dynamics of Pyroptosis in Mycobacteria Tuberculosis (Mtb) infected human macrophages. NBS Kontaktmøte
Conference poster

Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Ullmann, Sindre; Sætra, Ragnhild Sofie Ragnhildstveit; Marstad, Anne; Åsberg, Signe; Strand, Trine Aakvik; Flo, Trude Helen. (2019) Plasma membrane damage during Mycobacterium tuberculosis infection. The 4th Turning the Tide of Antimicrobial resistance meeting
Conference poster

Ullmann, Sindre; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Sætra, Ragnhild Sofie Ragnhildstveit; Marstad, Anne; Åsberg, Signe; Strand, Trine Aakvik; Flo, Trude Helen. (2019) Catching the moment - Correlative Light Electron Microscopy (CLEM) to study hostpathogen interactions in single cells, at ultimate spatial and temporal resolutions. Conference on Molecular Mechanisms of Inflammation
Conference poster

Haug, Markus; Meås, Hany Zakaria; Beckwith, Marianne Sandvold; Louet, Claire; Ryan, Liv; Hu, Z.; Landskron, Johannes; Nordbø, Svein Arne; Tasken, Kjetil; Yin, H. H.. (2019) Sensing of HIV-1 nucleic acids by TLR8 in human CD4+ T cells. 17th Congress of the International Union of Immunological Societies (IUIS)
Conference poster

Aksnes, Astrid; Høvik, Jens; Yadav, Mukesh; Noh, Jong Wook; Arnfinnsdottir, Nina Bjørk; Øvreeide, Ingrid Haga; Stokke, Bjørn Torger; Halaas, Øyvind; Hjelme, Dag Roar; Ellingsen, Reinold. (2019) Lab-on-a-chip platform for early detection of disease biomarkers. Digital Life 2019
Conference lecture

Meås, Hany Zakaria; Haug, Markus; Beckwith, Marianne Sandvold; Louet, Claire; Ryan, Liv; Hu, Z.; Landskron, Johannes; Nordbø, Svein Arne; Tasken, Kjetil; Yin, H. H.. (2019) Sensing of HIV-1 by TLR8 activates human T cells and reverses latency. International Conference on Molecular Mechanisms of Inflammation
Conference poster

Ullmann, Sindre; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Sætra, Ragnhild Sofie Ragnhildstveit; Marstad, Anne; Strand, Trine Aakvik; Flo, Trude Helen. (2019) Catching the moment - Correlative Light Electron Microscopy (CLEM) to study hostpathogen interactions in single cells, at ultimate spatial and temporal resolutions. The 4th Turning the Tide of Antimicrobial resistance meeting
Conference poster

Ullmann, Sindre; Sporsheim, Bjørnar; Egeberg, Kjartan Wøllo; Beckwith, Marianne Sandvold; Beckwith, Kai Sandvold; Sætra, Ragnhild Sofie Ragnhildstveit; Åsberg, Signe; Strand, Trine Aakvik; Flo, Trude Helen. (2019) Correlative light-electron microscopy investigations of single-cell dynamics in Mycobacteria tuberculosis infected human macrophages. Seeing is Believing - Imaging the Molecular Processes of Life
Conference poster

Sivakumar, Niruja; Dragset, Marte Singsås; Ioerger, Thomas R.; Loevenich, Maja; Haug, Markus; Marstad, Anne; Cardona, Pere Joan; Klinkenberg, Geir; Rubin, Eric J.; Steigedal, Magnus. (2019) Identification of novel virulence mechanisms in pathogenic mycobacteria. Conference on Molecular Mechanisms of Inflammation
Conference lecture

Sivakumar, Niruja; Dragset, Marte Singsås; Ioerger, Thomas R.; Loevenich, Maja; Haug, Markus; Marstad, Anne; Cardona, Pere Joan; Klinkenberg, Geir; Rubin, Eric J; Steigedal, Magnus. (2019) Global assessment of Mycobacterium avium subspecies hominissuis genetic requirement for virulence. Norwegian Biochemical Society 55th Contact Meeting
Conference lecture

Flo, Trude Helen; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Gidon, Alexandre; Ullmann, Sindre; Sætra, Ragnhild Sofie Ragnhildstveit. (2019) Plasma membrane damage by Mycobacterium tuberculosis induce inflammasome activation and pyroptosis in host macrophages. International Symposium on Discovery of Actionable Targets in Infectious Diseases
Interview

Flo, Trude Helen; Karlsen, Morten. (2019) Inflammasjon - betennelse.
Lecture

Flo, Trude Helen. (2019) Vaksiner - myter og fakta. FIRM - reisemedisinkonferanse
Interview

Flo, Trude Helen; Mcdonagh, Kirsten Eileen Hjelmeland. (2019) Podcast "Diagnose" - om antibiotikaresistens.
Conference poster

Meås, Hany Zakaria; Haug, Markus; Beckwith, Marianne; Louet, Claire; Ryan, Liv; Landskron, Johannes; Nordbø, Svein Arne; Tasken, Kjetil; Damås, Jan Kristian; Flo, Trude Helen. (2019) Sensing of HIV-1 by TLR8 activates human T cells and reverses Latency. Norsk Biokjemisk Selskap Kontaktmøte 2019

2018

Lecture

Gidon, Alexandre; Louet, Claire; Flo, Trude Helen. (2018) Single cell analysis reveals an IRF1/ACOD1 auto-paracrine loop controlled by IL-6/TNF-a to restrict persistent mycobacteria in human primary macrophage. 2nd Non Tuberculosis Mycobacteria European Conference
Conference poster

Beckwith, Marianne; Beckwith, Kai Sandvold; Ullmann, Sindre; Åsberg, Signe; Strand, Trine Aakvik; Flo, Trude Helen. (2018) Single-cell dynamics of pyroptosis in M. tuberculosis infected macrophages. EMBO workshop: The inflammasomes
Conference poster

Thorsvik, Silje; Granlund, Atle van Beelen; Svendsen, Tarjei Dahl; Bakke, Ingunn; Røyset, Elin Synnøve; Afroz, Wahida; Doseth, Berit; Flo, Trude Helen; Damås, Jan Kristian; Østvik, Ann Elisabet. (2018) Neutrophil Gelatinase-Associated Lipocalin (NGAL) is expressed in regenerative intestinal epithelium and proinflammatory cytokines induce NGAL in human colonoids. Digestive Disease Week (DDW
Conference poster

Meås, Hany Zakaria; Haug, Markus; Beckwith, Marianne; Louet, Claire; Ryan, Liv; Landskron, Johannes; Nordbø, Svein Arne; Tasken, Kjetil; Damås, Jan Kristian; Flo, Trude Helen. (2018) Sensing of HIV-1 by TLR8 activates human T cells and reverses Latency. Keystone HIV and Co-Infections: Pathogenesis, Inflammation and Persistence (X8)
Conference poster

Pedersen, Tina Therese; Fenstad, Mona H.; Jakobsen, Bente; Koksvik, Hege; Moksnes, T.; Wallenius, Marianne; Flo, Trude Helen; Haug, Markus. (2018) LOW LIPOCALIN-2 IN SYSTEMIC LUPUS ERYTHEMATOSUS PREGNANCIES - A POSSIBLE MECHANISM FOR LOSS OF TOLERANCE. Annual European Congress of Rheumatology (EULAR 2018)
Conference poster

Haug, Markus; Brede, Gaute; Håkerud, Monika; Nedberg, A; Gederaas, Odrun Arna; Edwards, Victoria Tudor; Flo, Trude Helen; Selbo, Pål Kristian; Høgset, Anders; Halaas, Øyvind. (2018) Photochemical internalization as a novel strategy to realize therapeutic cancer peptide vaccination. 5th European Congress of Immunology
Conference lecture

Flo, Trude Helen; Beckwith, Marianne; Meås, Hany Zakaria; Haug, Markus; Damås, Jan Kristian; Ryan, Liv; Louet, Claire. (2018) Sensing of HIV-1 by TLR8 activates human T cells and reverses latency. PhD defense
Conference lecture

Flo, Trude Helen; Beckwith, Kai Sandvold; Beckwith, Marianne. (2018) Single-cell dynamics of pyroptosis in Mycobacterium tuberculosis infected macrophages. PhD defense
Conference lecture

Flo, Trude Helen; Beckwith, Marianne; Beckwith, Kai Sandvold; Ullmann, Sindre; Åsberg, Signe; Marstad, Anne. (2018) Single-cell dynamics of pyroptosis in Mycobacterium tuberculosis infected macrophages. 51st Annual Meeting Society for Leukocyte Biology & International Endotoxin and Innate Immunity Society
Conference lecture

Flo, Trude Helen; Gidon, Alexandre; Lerm, Maria. (2018) Discovering new therapeutic targets and drugs to combat AMR tuberculosis: proteomics characterization and drug screening of mycobacterium-infected macrophages. Thon forskningsstiftelse prisutdeling
Interview

Tveter, Nina Elisabeth; Flo, Trude Helen. (2018) Ti millioner til NTNU-forsker.
Interview

Flo, Trude Helen; Bergesen, Norunn. (2018) Ti millioner til NTNU-forsker.
Lecture

Flo, Trude Helen. (2018) Vaccines - facts and myths. NBS Populærvitenskap og pizza
Interview

Flo, Trude Helen; Børstad, Johannes. (2018) God Ettermiddag Trøndelag Forskerprat: Tuberkulose - tildeling av FriMedBio forskerprosjekt.
Conference lecture

Flo, Trude Helen; Beckwith, Marianne; Beckwith, Kai Sandvold. (2018) Single-cell dynamics of pyroptosis in Mycobacterium tuberculosis infected macrophages. TOLL2018: Editing Innate Immunity
Conference poster

Beckwith, Kai Sandvold; Beckwith, Marianne; Ullmann, Sindre; Åsberg, Signe; Flo, Trude Helen. (2018) Single-cell dynamics of pyroptosis in M. Tuberculosis infected macrophages. EMBL Conference: From Images to Knowledge with ImageJ & Friends
Lecture

Beckwith, Kai Sandvold; Beckwith, Marianne; Ullmann, Sindre; Åsberg, Signe; Sætra, Ragnhild Sofie Ragnhildstveit; Strand, Trine Aakvik; Flo, Trude Helen. (2018) Damage and repair of host cell membranes during M. Tuberculosis infection. EMBL seminar
Conference lecture

Beckwith, Kai Sandvold; Beckwith, Marianne; Ullmann, Sindre; Åsberg, Signe; Strand, Trine Aakvik; Flo, Trude Helen. (2018) SINGLE-CELL DYNAMICS OF PYROPTOSIS IN M. TUBERCULOSIS INFECTED MACROPHAGES. Annual meeting Norwegian Research School for Infection biology and antimicrobials

2017

Conference lecture

Ibrahim, Hany; Haug, Markus; Flo, Trude Helen. (2017) HIV infection - How inflammation matters. Global health seminar Autumn 2017
Conference poster

Ibrahim, Hany; Kumashie, Kingsley; Flo, Trude Helen; Haug, Markus. (2017) Flow-cytometric analysis of autophagy in activated primary human CD4+ T cells under hypoxic conditions. NBS Contact Meeting 2017
Lecture

Flo, Trude Helen. (2017) Vaksiner - myter og fakta. Foredrag
Conference poster

Ostrop, Jenny; Kerntke, Christina; Sørbø, Håvard Gullik; Spanjers, Roos; Louet, Claire; Gidon, Alexandre; Lang, Roland; Flo, Trude Helen; Oudhoff, Menno. (2017) FcRγ is a central adaptor subunit for immune receptors on human macrophages. Annual Meeting of German Society for Immunology
Conference lecture

Flo, Trude Helen; Beckwith, Marianne; Beckwith, Kai Sandvold. (2017) The cell biology of Mycobacterium tuberculosis induced inflammasome activation and killing of host macrophages. The 35th annual meeeting Norwegian Society for Immunology
Conference poster

Ostrop, Jenny; Kerntke, Christina; Sørbø, Håvard Gullik; Jozefowski, Katrin; Hupfer, Thomas; Louet, Claire; Gidon, Alexandre; Lepenies, Bernd; Flo, Trude Helen; Lang, Roland. (2017) FcRγ is a central adaptor subunit for immune receptors on myeloid cells. EMBL course Bioimage Data Analysis - poster session
Conference poster

Haug, Markus; Ibrahim, Hany; Kumashie, Kingsley; Flo, Trude Helen. (2017) Analysis of autophagy in activated primary human CD4+T cells under hypoxic conditions. IMMUNOLOGY 2017 (Annual Meeting of The American Association of Immunologists)
Conference poster

Beckwith, Marianne; Beckwith, Kai Sandvold; Strand, Trine Aakvik; Flo, Trude Helen. (2017) In situ imaging of pyroptosis caused by Mycobacterium tuberculosis. Keystone X5: From Innate Immunity to Inflammatory Disease
Conference lecture

Flo, Trude Helen. (2017) The inner life of a mycobacterium infected macrophage. invitert foredragsholder
Conference lecture

Flo, Trude Helen. (2017) The inner life of mycobacterium-infected macrophages. Invitert foredragsholder
Lecture

Flo, Trude Helen. (2017) Antibiotikaresistens. BodyWorlds Vital
Conference poster

Gidon, Alexandre; Åsberg, Signe; Louet, Claire; Ryan, Liv; Haug, Markus; Flo, Trude Helen. (2017) Persistent mycobacteria evade an antibacterial program mediated by phagolysosomal TLR7/8/MyD88 in human primary macrophages. Pattern Recognition Signaling: From Innate Immunity to Inflammatory Disease (X5)
Interview

Brandslet, Steinar; Flo, Trude Helen. (2017) Sånn skjuler tuberkulose seg i kroppen.
Conference lecture

Bösl, Korbinian; Ibrahim, Hany; Richard, Gabriel Mary; Giambelluca, Miriam; Haug, Markus; Flo, Trude Helen; Kandasamy, Richard Kumaran. (2017) Integrative analysis of the inflammatory signalling kinome landscape CRISPR/Cas9-based genetic screens for identification of viral host factors. CSAMA 2017
Conference poster

Mildenberger, Jennifer; Johansson, Ida; Kjøbli, Eli; Damås, Jan Kristian; Flo, Trude Helen; Bjørkøy, Geir. (2017) N-3 PUFAs induce inflammatory tolerance by formation of KEAP1 containing p62-bodies. ER Stress, Autophagy & Immune System.

2016

Conference poster

Gidon, Alexandre; Åsberg, Signe Elisabeth; Louet, Claire; Ryan, Liv; Flo, Trude Helen. (2016) Mycobacterium avium interfering with phagosome maturation evades an antibacterial program activated by phagolysosomal TLR7/8/MyD88 in human primary macrophages. Tuberculosis 2016 "Interdisciplinary research on tuberculosis and pathogenic mycobacteria"
Contribution to radio or TV

NRK, Schrödingers katt; Flo, Trude Helen; Steigedal, Magnus. (2016) Antibiotikaresistens.
Conference poster

Gidon, Alexandre; Åsberg, Signe Elisabeth; Louet, Claire; Ryan, Liv; Flo, Trude Helen. (2016) Inflammatory Encounters of Mycobacteria in Space and Time. EMBO:EMBL Symposia : Innate Immunity in Host-Pathogen Interactions
Lecture

Awuh, Jane Atesoh; Flo, Trude Helen; Haug, Markus; Steigedal, Magnus; Halaas, Øyvind; Damås, Jan Kristian; Mildenberger, Jennifer; Marstad, Anne; Louet, Claire; Stenvik, Jørgen. (2016) Keap1 regulates inflammatory signaling in M. avium infected human macrophages. International Congress of Immunology
Conference lecture

Flo, Trude Helen. (2016) The inner life of a mycobacterium-infected macrophage. International Conference on Molecular Mechanisms of Inflammation
Lecture

Gidon, Alexandre; Åsberg, Signe Elisabeth; Louet, Claire; Ryan, Liv; Flo, Trude Helen. (2016) Mycobacterium avium evades an antibacterial program mediated by phagolysosomal TLR7/8/MyD88. SCANDEM 2016
Conference poster

Gidon, Alexandre; Åsberg, Signe Elisabeth; Louet, Claire; Ryan, Liv; Flo, Trude Helen. (2016) Mycobacterium avium evades an antibacterial program mediated by phagolysosomal TLR7/8/MyD88. International Conference on Mechanisms of Molecular Inflammation
Interview

Flo, Trude Helen. (2016) Årstiden du føder kan påvirke barnets helse.
Conference poster

Ostrop, Jenny; Jozefowski, Katrin; Sørbø, Håvard Gullik; Zimmermann, Stephanie; Lepenies, Bernd; Flo, Trude Helen; Lang, Roland. (2016) MINCLE-SYK signaling contributes to activation of primary human APC by mycobacterial cord factor and the novel adjuvant TDB. Mechanisms of Molecular Inflammation
Lecture

Awuh, Jane Atesoh; Haug, Markus; Mildenberger, Jennifer; Marstad, Anne; Louet, Claire; Chau, Do Ngoc Phuc; Stenvik, Jørgen; Damås, Jan Kristian; Halaas, Øyvind; Flo, Trude Helen. (2016) Keap1 regulates inflammatory signaling in Mycobacterium avium-infected human macrophages. IBA kickoff meeting
Lecture

Awuh, Jane Atesoh; Haug, Markus; Mildenberger, Jennifer; Marstad, Anne; Louet, Claire; Chau, Do Ngoc Phuc; Stenvik, Jørgen; Damås, Jan Kristian; Halaas, Øyvind; Flo, Trude Helen. (2016) Keap1 regulates inflammatory signaling in Mycobacterium avium-infected human macrophages. NSI Annual Meeting
Conference lecture

Flo, Trude Helen. (2016) the inner life of mycobacterium-infected macrophages. Disputas
Lecture

Flo, Trude Helen. (2016) Vaksiner - myter og fakta. Kunnskapsbyen
Conference poster

Mærk, Mali; Aakvik, Trine; Bandyopadhyay, Sulalit; Flo, Trude Helen; Steigedal, Magnus. (2016) Colorimetric assay for detecting ESX-3 secretion system disruption in mycobacteria. EMBO Conference Tuberculosis 2016: Interdisciplinary research on tuberculosis and pathogenic mycobacteria
Conference poster

Mærk, Mali; Aakvik, Trine; Flo, Trude Helen; Steigedal, Magnus. (2016) Screening for drug candidates targeting the mycobacterial ESX-3 system. Keystone Symposium: Tuberculosis Co-Morbidities and Immunopathogenesis
Conference poster

Mærk, Mali; Aakvik, Trine; Flo, Trude Helen; Steigedal, Magnus. (2016) Colorimetric assay for detecting ESX-3 secretion system disruption in mycobacteria. Conference on Molecular Mechanisms of Inflammation
Lecture

Haug, Markus; Ibrahim, Hany; Flo, Trude Helen. (2016) Bridging innate and adaptive immunity: Innate immune functions in adaptive T cells. IKM Wednesday Meeting
Conference lecture

Stenvik, Jørgen; Bergstrøm, Bjarte; Aune, Marie Hjelmseth; Awuh, Jane Atesoh; Kojen, June Frengen; Blix, Kjetil Jordahl; Ryan, Liv; Flo, Trude Helen; Mollnes, Tom Eirik; Espevik, Terje. (2016) TLR8 Senses Staphylococcus aureus RNA in Human Primary Monocytes and Macrophages and Induces IFN-b Production via a TAK1–IKKb–IRF5 Signaling Pathway. International Conference on Molecular Mechanisms of Inflammation
Conference poster

Mildenberger, Jennifer; Johansson, Ida; Kjøbli, Eli; Damås, Jan Kristian; Flo, Trude Helen; Bjørkøy, Geir. (2016) The effect of n-3 PUFAs on ubiquitination and inflammation in human macrophages. New approaches to study ubiquitin and ubiquitin-like modifications
Conference poster

Ibrahim, Hany; Kumashie, Kingsley; Flo, Trude Helen; Haug, Markus. (2016) Flow-Cytometric analysis of autophagy in activated primary human CD4+ T cells under hypoxic conditions. International conference on mechanisms of molecular inflammation
Conference poster

Kannan, Nisha; Haug, Markus; Flo, Trude Helen; Steigedal, Magnus. (2016) Mycobacterium smegmatis mutant a potential live bacterial vaccine vector for antigen delivery. EMBO Tuberculosis
Conference poster

Dragset, Marte Singsås; Ioerger, Thomas R.; Helland, Maja; Haug, Markus; Marstad, Anne; Klinkenberg, Geir; Wei, Jun Rong; Rubin, Eric J; Steigedal, Magnus; Flo, Trude Helen. (2016) A mutant toolbox to study mycobacterial infections. CONFERENCE ON MOLECULAR MECHANISMS OF INFLAMMATION
Conference poster

Kannan, Nisha; Haug, Markus; Flo, Trude Helen; Steigedal, Magnus. (2016) Mycobacterium smegmatis mutant a potential live bacterial vaccine vector for antigen delivery. Molecular Mechanisms of Inflammation

2015

Interview

Spilde, Ingrid; Flo, Trude Helen. (2015) E. coli-bakterie hjalp syke mus.
Conference lecture

Flo, Trude Helen. (2015) Host pathogen interactions in mycobacterial infections, point to novel targets and test vaccine candidates (and/or adjuvants) in vitro in cells. Joint GLOBVAC and TBVI meeting on ’The State of the Art of TB Vaccine R&D in Europe’
Interview

Flo, Trude Helen; Dale, Åsta. (2015) Er det riktig å gi antibiotika mot lungebetennelse?.
Interview

Flo, Trude Helen. (2015) Fant protein som hindrer immunforsvaret å løpe løpsk.
Conference lecture

Bergstrøm, Bjarte; Aune, Marie Hjelmseth; Awuh, Jane Atesoh; Kojen, June Frengen; Ryan, Liv; Flo, Trude Helen; Mollnes, Tom Eirik; Stenvik, Jørgen; Espevik, Terje. (2015) TLR8 is a sensor for Staphylococcus aureus RNA in human monocytes and macrophages. 12th International Conference on Innate Immunity
Conference poster

Åsberg, Signe Elisabeth; Awuh, Jane Atesoh; Shrestha, Birendra Kumar; Flo, Trude Helen. (2015) Autophagy in macrophages infected with Mycobacterium avium is dependent on TLR2. Keystone Symposia Innate Immunity and Determinants of Microbial Pathogenesis
Conference poster

Thorsvik, Silje; Damås, Jan Kristian; Granlund, Atle van Beelen; Flo, Trude Helen; Bakke, Ingunn; Østvik, Ann Elisabet; Sandvik, Arne Kristian. (2015) Fecal Neutrophil Gelatinase Associated Lipocalin as a biomarker for Inflammatory Bowel Disease. AIBD 2015
Conference lecture

Flo, Trude Helen; Awuh, Jane Atesoh; Haug, Markus; Damås, Jan Kristian; Marstad, Anne; Steigedal, Magnus; Halaas, Øyvind; Stenvik, Jørgen; Mildenberger, Jennifer. (2015) INFLAMMATORY SIGNALING IN MYCOBACTERIUM AVIUM INFECTED HUMAN MACROPHAGES. Toll 2015: Targeting Innate Immunity
Conference poster

Haug, Markus; Brede, Gaute; Flo, Trude Helen; Høgset, Anders; Halaas, Øyvind. (2015) Photochemical internalization as novel vaccination technology. NBS Contact Meeting 2015
Interview

Steigedal, Magnus; Flo, Trude Helen. (2015) Ingen vil ta regningen for nye antibiotika.
Conference lecture

Flo, Trude Helen; Awuh, Jane Atesoh; Haug, Markus; Steigedal, Magnus; Marstad, Anne; Mildenberger, Jennifer; Damås, Jan Kristian; Halaas, Øyvind; Louet, Claire; Stenvik, Jørgen. (2015) Keap1 regulates inflammatory signaling in M. avium infected human macrophages. Keystone symposium: Innate Immunity and Determinants of Microbial Pathogenesis
Conference lecture

Flo, Trude Helen. (2015) Vaksiner: fra empiri til revers vaksinologi. Norsk Kjemisk Selskap
Lecture

Flo, Trude Helen. (2015) Scientific career - advise for young investigators. Seminar for stjerneforskerne /Yngre forskere
Conference lecture

Flo, Trude Helen. (2015) The inner life of a mycobacterium-infected macrophage. Invited lecturer
Conference lecture

Flo, Trude Helen. (2015) The inner life of a mycobacterium-infected macrophage. Top Gear in Science
Interview

Weisser, Agnethe; Flo, Trude Helen. (2015) Slik løper immunforsvaret løpsk.
Interview

Bazilchuk, Nancy Reney; Flo, Trude Helen. (2015) Uncovering the secrets of immune system invaders.
Lecture

Flo, Trude Helen. (2015) Researchers Night - Fornuft og følelser. Forskningsdagene - Researchers Night
Interview

Flo, Trude Helen; Awuh, Jane A; Stenvik, Jørgen. (2015) Slik lurer bakterier immunsystemet.
Interview

Steigedal, Magnus; Flo, Trude Helen. (2015) Nobody wants to foot the bill for new antibiotics.
Contribution to radio or TV

Flo, Trude Helen. (2015) Newton - hva er vaksine?.
Conference poster

Haug, Markus; Ibrahim, Hany; Brede, Gaute; Flo, Trude Helen; Høgset, Anders; Halaas, Øyvind. (2015) Photochemical internalization as novel vaccination technology to enhance antigen-specific CD8+ T cell responses. 4th European Congress of Immunology (ECI 2015)
Interview

Spilde, Ingrid; Flo, Trude Helen. (2015) Blir immunforsvaret sterkere etter sykdom?.

2014

Conference lecture

Mildenberger, Jennifer; Johansson, Ida; Nonstad, Unni; Flo, Trude Helen; Bjørkøy, Geir. (2014) The interplay of autophagy and inflammation in disease prevention by omega 3 polyunsaturated fatty acids. NBS vintermøte Røros 2014
Lecture

Flo, Trude Helen. (2014) CEMIR: inflammasjonsforskning og prestasjonskultur. Presentasjonsklyngen
Lecture

Flo, Trude Helen; Dragset, Marte Singsås; Åsberg, Signe Elisabeth. (2014) Forskningstorget, vaksinasjon. Forskningstorget
Interview

Flo, Trude Helen. (2014) VAKSINELANDET Nå skal babyer få enda en vaksine Vil at barn skal ta totalt 11 vaksiner.
Interview

Flo, Trude Helen. (2014) Norske babyer får ny vaksine - den ellevte i rekken: - Forstår at foreldre er skeptiske.
Conference poster

Kannan, Nisha; Steigedal, Magnus; Flo, Trude Helen. (2014) Investigation of mutant Mycobacterium smegmatis as a vector for a Tuberculosis vaccine. the 9th International Conference on the Pathogenesis of Mycobacterial Infections
Conference poster

Kannan, Nisha; Steigedal, Magnus; Flo, Trude Helen; Haug, Markus. (2014) Creating efficient vaccine candidates against Tuberculosis using mutant Mycobacterium smegmatis. NBS contact meeting 2014
Conference poster

Beckwith, Marianne; Beckwith, Kai Sandvold; Sikorski, Pawel; Flo, Trude Helen; Halaas, Øyvind. (2014) Correlative imaging by light microscopy and FIB/SEM tomography. NTNU NanoLab 10 Year Anniversary
Conference poster

Dragset, Marte Singsås; Zhang, Yanjia; Ioerger, Thomas; Pritchard, Justin; Flo, Trude Helen; Sacchettini, James; Steigedal, Magnus. (2014) Identification of Mycobacterial Iron Uptake Genes. 9th International Conference on the Pathogenesis of Mycobacterial Infections
Conference lecture

Flo, Trude Helen; Awuh, Jane Atesoh; Haug, Markus; Marstad, Anne; Steigedal, Magnus; Damås, Jan Kristian; Halaas, Øyvind; Stenvik, Jørgen. (2014) Keap1 regulates inflammatory signaling and autophagy in M. avium infected human macrophages. The First Joint Meeting of "Nordic, Spanish & French (NSF) Autophagy Networks"
Lecture

Dragset, Marte Singsås; Steigedal, Magnus; Flo, Trude Helen; Valla, Svein. (2014) Identification of Genes Involved in Mycobacterial Iron Uptake. NBS Contact Meeting, minisymposium

2013

Conference lecture

Flo, Trude Helen. (2013) Molecular mechanisms of mycobacterial infections. An overview. Norwegian Society for Immunology 30th anniversary meeting
Lecture

Flo, Trude Helen. (2013) Betent kunnskap. Kunnskapsbyen
Conference lecture

Flo, Trude Helen. (2013) Lipocalin 2 in mucosal immunity. Workshop on Infectious Diseases and Molecular Methods
Interview

Flo, Trude Helen; ntnuinfo, ntnuinfo. (2013) Mycobacteria.
Interview

Monsen, Tor; Flo, Trude Helen. (2013) Leter etter ny vaksine.
Conference lecture

Haug, Markus; A., Habtamu Chonchoro; Awuh, Jane Atesoh; Steigedal, Magnus; Marstad, Anne; Halaas, Øyvind; Flo, Trude Helen. (2013) Mycobacteria-specific Immunity in HIV-infected Individuals and Healthy Controls. Workshop on Infectious Diseases and Molecular Methods
Conference lecture

Haug, Markus; Flo, Trude Helen; Høgset, Anders; Halaas, Øyvind. (2013) Photochemical internalization (PCI) as novel strategy to enhance efficacy of vaccines. Instituttseminar IKM
Conference poster

Åsberg, Signe; Birendra, Kumar Shrestha; Flo, Trude Helen; Haug, Markus; Awuh, Jane Atesoh. (2013) The interplay of C-type lectins and Toll-like receptors in shaping host-responses to mycobacteria. Practical course: Current Methods in Cell Biology
Conference poster

Haug, Markus; Awuh, Jane Atesoh; Steigedal, Magnus; Kojen, June Frengen; Marstad, Anne; Halaas, Øyvind; Flo, Trude Helen. (2013) T regulatory and T helper 17 cells in mouse Mycobacterium avium infection. Keystone Symposium: Host Response in Tuberculosis
Interview

Weisser, Agnethe; Espevik, Terje; Flo, Trude Helen. (2013) Se krigercellene gå til angrep.
Interview

Jakobsen, Siw Ellen; Espevik, Terje; Flo, Trude Helen. (2013) Når forsvarerne blir fienden.
Conference lecture

Dragset, Marte Singsås; Steigedal, Magnus; Valla, Svein; Flo, Trude Helen. (2013) Riding the Ferrous Wheel: Identification and Study of Genes Involved in Mycobacterial Iron Acquisition. Department seminar at the Department of Biotechnology
Conference lecture

Steigedal, Magnus; Siegrist, Sloan; Dragset, Marte Singsås; Haug, Markus; Ahmad, Rushdy; Rubin, Eric J; Flo, Trude Helen. (2013) EspG of Esx-3 contributes to Mycobactin-mediated Iron Acquisition and Protein secretion in Mycobacteria. Norwegian Bichemical Society Contact Meeting 2013
Conference poster

Steigedal, Magnus; Siegrist, Sloan; Dragset, Marte Singsås; Haug, Markus; Ahmad, Rushdy; Rubin, Eric J; Flo, Trude Helen. (2013) EspG Contributes to Mycobactin-Mediated Iron Acquisition and Protein Secretion in Mycobacteria. Keystone symposia: Tuberculosis: Understanding the enemy
Conference poster

Awuh, Jane Atesoh; Flo, Trude Helen; Haug, Markus; Steigedal, Magnus; Shrestha, Birendra Kumar; Do, Chau Ngoc Phuc; Marstad, Anne; Damås, Jan Kristian; Halaas, Øyvind. (2013) Stress related protein regulates inflammatory signaling and autophagy in human macrophages during M. avium infection. GlobVac conference
Conference lecture

Flo, Trude Helen; Haug, Markus; Steigedal, Magnus; Awuh, Jane Atesoh; Marstad, Anne; Shrestha, Birendra Kumar. (2013) Mycobacterial survival and killing in host macrophages. CEMIR opening seminar
Conference poster

Flo, Trude Helen; Awuh, Jane Atesoh; Haug, Markus; Steigedal, Magnus; Damås, Jan Kristian; Halaas, Øyvind; Marstad, Anne; Shrestha, Birendra Kumar; Do, Ngoc Phuc Chau. (2013) The role of a stress-related protein in inflammatory signalling and intracellular survival of mycobacteria. Keystone symposium: Keystone Symposium: Host Response in Tuberculosis

2012

Conference lecture

Haug, Markus; A., Habtamu Chonchoro; Awuh, Jane Atesoh; Steigedal, Magnus; Halaas, Øyvind; Flo, Trude Helen. (2012) Detection of mycobacteria-specific effector T cells using multicolor flow-cytometry. Norsk Flowcytometri Forening (NFCF) Meeting
Conference poster

Haug, Markus; Awuh, Jane Atesoh; Steigedal, Magnus; Kojen, June Frengen; Marstad, Anne; Halaas, Øyvind; Flo, Trude Helen. (2012) Interplay of Immune Effector Mechanisms Contributing to Containment of Infection in Liver and Spleen of Mycobacterim avium Infected Mice. Tuberculosis 2012
Lecture

Steigedal, Magnus; Haug, Markus; Halaas, Øyvind; Marstad, Anne; Dragset, Marte Singsås; Awuh, Jane Atesoh; Flo, Trude Helen. (2012) Tuberkulose tar millioner av liv. Kan vi finne en løsning?. Forskningsdagene: Forsker til lunsj
Conference lecture

Flo, Trude Helen; Awuh, Jane Atesoh; Haug, Markus; Halaas, Øyvind; Steigedal, Magnus; Marstad, Anne. (2012) Host-pathogen relations in mycobacterial infections. Instituttseminar IKM
Conference poster

Haug, Markus; Awuh, Jane Atesoh; Steigedal, Magnus; Kojen, June Frengen; Marstad, Anne; Nordrum, Ivar Skjåk; Halaas, Øyvind; Flo, Trude Helen. (2012) Tissue Inflammatory Responses and Containment of Infection in Mycobacterium avium Infected Mice. 7th conference for Global health and Vaccination research
Conference poster

Flo, Trude Helen; Haug, Markus; Awuh, Jane Atesoh; Halaas, Øyvind; Steigedal, Magnus; Marstad, Anne; Kojen, June Frengen; Nordrum, Ivar Skjåk. (2012) Tissue Inflammatory Responses and Containment of Infection in Mycobacterium avium Infected Mice. Tuberculosis 2012
Conference lecture

Flo, Trude Helen; Steigedal, Magnus; Damås, Jan Kristian; Strong, Roland; Rognstad, Øyvind Bakken; Mobley, Harry LT; Vadstein, Olav; Bakke, Ingrid. (2012) Lipocalin 2 in protection of mucosal surfaces and shaping of intestinal microflora. EMBO|EMBL Symposium : New Perspectives on Immunity to Infection
Conference poster

A., Habtamu Chonchoro; Damås, Jan Kristian; Waagsbø, Bjørn; Flo, Trude Helen; Haug, Markus. (2012) Analysis of mycobacteria-specific T-cell function in HIV-infected individuals and healthy controls. 7th conference for Global health and Vaccination research
Conference lecture

Flo, Trude Helen; Steigedal, Magnus; Rognstad, Øyvind Bakken; Damås, Jan Kristian; Strong, Roland; Mobley, Harry LT. (2012) Lipocalin 2 in protection of mucosal surfaces and shaping of intestinal microflora. Norwegian Biochemical Society
Lecture

Steigedal, Magnus; Dragset, Marte Singsås; Haug, Markus; Awuh, Jane Atesoh; Halaas, Øyvind; Marstad, Anne; Flo, Trude Helen. (2012) Tuberkulose tar millioner av liv. Kan vi finne en løsning?. Forskningsdagene: Forsker til lunsj
Conference lecture

Steigedal, Magnus; Flo, Trude Helen; Haug, Markus; Dragset, Marte Singsås; Awuh, Jane Atesoh; Halaas, Øyvind. (2012) Iron uptake in mycobacteria: Searching for novel drug targets. Department seminar at the Department of Biotechnology

2011

Conference poster

Haug, Markus; Awuh, Jane Atesoh; Steigedal, Magnus; Nordrum, Ivar Skjåk; Halaas, Øyvind; Flo, Trude Helen. (2011) Dynamics of the adaptive immune response to Mycobacterium avium in a mouse infection model. Keystone Symposia on Tuberculosis and Mycobacteria
Conference lecture

Haug, Markus; Awuh, Jane Atesoh; Nordrum, Ivar Skjåk; Halaas, Øyvind; Flo, Trude Helen. (2011) The role of regulatory T cells in mycobacterial infections. Onsdagsmøte for DMF, NTNU og St. Olavs Hospital;
Conference lecture

Flo, Trude Helen. (2011) Host-pathogen relations in mycobacterial infections. Workshop on molecular methods

2010

Conference lecture

Flo, Trude Helen; Awuh, Jane Atesoh; Halaas, Øyvind; Steigedal, Magnus; Cangelosi, Gerard; Ryan, Liv; Espevik, Terje; Husebye, Harald; Strong, Roland; Haug, Markus. (2010) Intracellular mycobacterium avium intersect transferrin in the Rab11+recycling endocytotic pathway and avoid lipocalin 2 trafficking the lysosomal pathway. NBS kontaktmøte 2010

2009

Conference poster

Flo, Trude Helen; Awuh, Jane Atesoh; Halaas, Øyvind; Haug, Markus; Steigedal, Magnus; Strong, Roland; Cangelosi, Gerard; Husebye, Harald; Ryan, Liv; Akira, Shizuo. (2009) Intracellular Mycobacterium avium enters the Rab11+ Recycling Endocytic Pathway to Access Transferrin and Escape from Lcn2 trafficking the Lysosomal Pathway. Keystone symposium "Tuberculosis: Biology, Pathology and Therapy"
Lecture

Flo, Trude Helen; Halaas, Øyvind. (2009) UTOPIA - hvordan ser morgendagens samfunn ut mhp Medisinsk teknologi?. UKEkonferansen
Conference lecture

Haug, Markus; Awuh, Jane Atesoh; Steigedal, Magnus; Halaas, Øyvind; Flo, Trude Helen. (2009) Adaptive immunity to M. avium in a mouse infection model. 4th Conference on Global Health and Vaccination Research
Conference poster

Dragset, Marte Singsås; Steigedal, Magnus; Flo, Trude Helen; Valla, Svein. (2009) Searching future therapies for tuberculosis: Identification of genes involved in /Mycobacterium avium/ intracellular survival in macrophages. NBS kontaktmøte
Lecture

Flo, Trude Helen; Halaas, Øyvind; Awuh, Jane Atesoh; Steigedal, Magnus; Rognstad, Øyvind Bakken. (2009) Immunforsvar - hvordan ser kroppens krigere ut?Kroppens egne krigere, immuncellene, hvordan ser de ut og hvordan virker de? Her kan dere se på cellene i vanlig lysmikroskop og få demonstrert hvordan vi kan bruke fluorescens og konfokalmikroskopi til å studere infeksjoner. Researchers Night 2009
Lecture

Flo, Trude Helen. (2009) Nepal and Agreement on collaboration between The Medical Faculty NTNU and Kathmandu University School of Medical Sciences. Tirsdagsmøte for DMF, NTNU og St. Olavs Hospital
Conference poster

Haug, Markus; Steigedal, Magnus; Flo, Trude Helen; Halaas, Øyvind. (2009) Development of T cell activation assays to measure vaccine efficiency towards mycobacteria. NBS kontaktmøte
Conference poster

Steigedal, Magnus; Rognstad, Øyvind Bakken; Lieungh, Ida; Damås, Jan Kristian; Flo, Trude Helen. (2009) Lipocalin 2 - a novel innate immunity protein with antimicrobial effects: Role in urinary tract infection (UTI). NBS Vintermøte 2009
Conference poster

Halaas, Ø.; Steigedal, Magnus; Haug, Markus; Awuh, Jane Atesoh; Husebye, Harald; Ryan, Liv; Espevik, Terje; Flo, Trude Helen. (2009) Intracellular Mycobacterium avium Enters the Rab11+ Recycling End¬ocytic Pathway to Access Transferrin and Escape from Lcn2 trafficking the Lysosomal Pathway. ASM General Meeting
Conference poster

Awuh, Jane Atesoh; Halaas, Øyvind; Haug, Markus; Flo, Trude Helen; Steigedal, Magnus; Brech, Andreas; Akira, Shizuo; Strong, Roland; Espevik, Terje; Ryan, Liv. (2009) Intracellular Mycobacterium avium enters the Rab11+ Recycling Endocytic Pathway to Access Transferrin and Escape from Lcn2 trafficking the Lysosomal Pathway. 4th Conference on Global Health and Vaccination Research (GlobVac)

2008

Conference lecture

Flo, Trude Helen. (2008) Lipokalin 2 i mykobakterielle infeksjoner. Tirsdagsmøte for DMF, NTNU og St. Olavs Hospital
Conference poster

Flo, Trude Helen; Halaas, Øyvind; Steigedal, Magnus; Espevik, Terje; Ryan, Liv; Strong, Roland; Cangelosi, Gerard; Brech, Andreas; Kaiser, Bret. (2008) Lipocalin 2 protects against mycobacterial infections during the acute phase, but not in long term chronic infections. Keystone Symposia on Innate Immunity: Signaling Mechanisms
Conference poster

Rognstad, Øyvind Bakken; Damås, Jan Kristian; Steigedal, Magnus; Knowles, Margaret; Angelsen, Anders; Flo, Trude Helen. (2008) The presence of Lipocalin 2 as an antimicrobial protein in urine from urinary tract infections. The 10th Biennial Meetin of the International Endotoxin and Innate and Immunity Society
Conference lecture

Flo, Trude Helen; Halaas, Øyvind; Steigedal, Magnus; Husebye, Harald; Ryan, Liv. (2008) Lipocalin 2 in mycobacterial infections. Tirsdagsmøte
Conference poster

Steigedal, Magnus; Flo, Trude Helen; Halaas, Øyvind; Ryan, Liv; Espevik, Terje. (2008) Mycobacteria are Lipocalin 2-sensitive but evade long term growth suppression by excluding lipocalin 2 from their intracellular compartment. ASM General Meeting
Conference lecture

Steigedal, Magnus; Flo, Trude Helen; Espevik, Terje; Rognstad, Øyvind Bakken. (2008) Lipocalin 2- a novel innate immunity protein with antimicropbial effect: Role in urinary tract infection (UTI). The Norwegian Biochemical Society 44th Contact meeting
Conference lecture

Flo, Trude Helen; Halaas, Øyvind; Steigedal, Magnus; Ryan, Liv. (2008) Mycobacteria are sensitive to lipocalin 2 but evade an intracellular lipocalin 2-defense by interfering with trafficking in macrophages. The 10th Biennial Meeting of the International Endotoxin and Innate Immunity Society

2007

Conference lecture

Steigedal, Magnus; Flo, Trude Helen; Rognstad, Øyvind Bakken. (2007) Iron thievery in Urinary Tract Infection (UTI). Seminar series IKM
Conference lecture

Steigedal, Magnus; Flo, Trude Helen; Halaas, Øyvind. (2007) Iron thievery in Mycobacterial infections. Microbiology and molecular genetics seminar, department of Biotechnology
Conference lecture

Halaas, Øyvind; Steigedal, Magnus; Flo, Trude Helen. (2007) Lipocalin 2 in innate immune responses to Mycobacterium avium. Miniseminar
Conference lecture

Halaas, Øyvind; Steigedal, Magnus; Flo, Trude Helen. (2007) Tuberkuloseforskning? I Trondheim?. Instituttsamling
Conference lecture

Halaas, Øyvind; Steigedal, Magnus; Flo, Trude Helen. (2007) Mycobacterium avium: Nutrition and escaping immune detection. Engaging in global health research
Conference lecture

Halaas, Øyvind; Steigedal, Magnus; Flo, Trude Helen. (2007) Lipocalin 2 in defence against mycobacteria. Vintermøtet

2002

Conference poster

Moen, Siv H; Flo, Trude Helen; Ryan, Liv; Espevik, Terje; Sundan, Anders. (2002) Generation and functional characterization of human toll-like (TLR) 6. 38.Biokjemiske kontaktmøte Functional genomics-the mosaics of life
Conference poster

Ryan, Liv; Flo, Trude Helen; Takeuchi, Osamu; Lien, Egil; Halaas, Øyvind; Akira, Shizuo; Skjåk-Bræk, Gudmund; Espevik, Terje. (2002) Involvement of TLR2 and TLR4 in activation of monocytes/macrophages by mannuronic acid polymers. The International Union of Biochemistry and Molecular Biology 7th IUBMB Conference RECEPTOR-LIGAND INTERACTIONS Molecular, Physiological and Pharmacological Aspects
Conference poster

Ryan, Liv; Flo, Trude Helen; Takeuchi, Osamu; Lien, Egil; Halaas, Øyvind; Akira, Shizuo; Skjåk-Bræk, Gudmund; Espevik, Terje. (2002) Involvement of TLR2 and TLR4 in activation of monocytes/macrophages by mannuronic acid polymers. 38.Biokjemiske kontaktmøte Functional genomics-the mosaics of life

2001

Conference poster

Western, K. H.; Thompson, Keith; Aarvak, Tanja; Flo, T. H.; Espevik, T; Bogen, Bjarne. (2001) Toll-like receptors are involved in antigen capture and presentation on MHC class II molecules to CD4+ T cells and serve as a link between innate and adaptive immunity. Meeting: Interfaces between innate and adaptive immunity (J3).
Conference poster

Western, K. H.; Thompson, Keith; Aarvak, Tanja; Flo, T. H.. (2001) Toll-like receptors are involved in antigen capture and presentation on MHC class II molecules to CD4+ T cells and serve as a link between innate and adaptive immunity. Interfaces between innate and adaptive immunity (J3).
Conference lecture

Wang, Jacob Edward; Warris, A.; Ellingsen, Espen Alme; Jørgensen, Pål Foyn; Flo, T. H.; Espevik, T; Solberg, Rigmor; Verweij, P. E.; Aasen, Ansgar Oddne. (2001) Involvement of CD 14 and toll-like receptors in signaling by Aspergillus hypae. Surigal Infection Society-Europe
Conference poster

Wang, Jacob Edward; Warris, A.; Ellingsen, Espen Alme; Jørgensen, Pål Foyn; Flo, T. H.; Espvik, T.; Solberg, Rigmor; Verweij, P. E.; Aasen, Ansgar Oddne. (2001) Activation of Leykocytes By Hyphal Fragments: Invvolvment of CD14 And Toll-Like Receptors. Sur In Soc 21th annual Meeting
Conference poster

Flo, Trude Helen; Ryan, Liv; Lien, Egil; et, al.. (2001) Involvement of TLRs in cell activation by an alginate polysaccharide, mannuronic acid polymer. Keystone Symposia
Conference poster

Flo, Trude Helen. (2001) Involvement of TLR2 and TLR4 in activation of monocyte/macrophages by mannuronic acid polymers. 2nd Meeting on Septic Shock caused by Gram-positive bacteria.
Conference poster

Western, Karoline H; Aarvik, Tanja; Thompson, Ketih; Flo, Trude Helen; Espevik, Terje. (2001) Toll-like receptors are involved in antigen capture and presentation on MHC class II molecules to CD4+ T cells and serve as a link between innate and adaptive immunity. Keystone Symposia
Conference poster

Halaas, Øyvind; Flo, Trude Helen; Torp, Sverre Helge; Ryan, Liv; et, al.. (2001) Regulated expression of TLRR2 in human blood cells. Keystone Symposia

2000

Conference lecture

Flo, Trude Helen. (2000) Bacterial activation of innate immune cells: The human Toll-like receptors. Molekulare Grundlagen der Differenziering und Aktivierung mononukleärer Phagozyten
Lecture

Flo, Trude Helen; Ryan, Liv; Halaas, Øyvind; Dybdal, Brit; Lien, Egil; Sundan, Anders; Espevik, Terje. (2000) Detection of soluble TLR2 in human serum samples by ELISA. The 6th Conference of The International Endotoxin Society
Lecture

Halaas, Øyvind; Flo, Trude Helen; Dybdal, Brit; Torp, Sverre Helge; Lien, Egil; Sundan, Anders; Espevik, Terje. (2000) Expression pattern of toll-like receptor 2. 6th Conference of the International Endotoxin Society
Lecture

Flo, Trude Helen; Halaas, Øyvind; Lien, Egil; Ryan, Liv; Teti, Guiseppe; Golenbock, Douglas T.; Sundan, Anders; Espevik, Terje. (2000) Human toll-like receptor 2 mediates monocyte activation by listeria monocytogenes, but not by group B streptococci or lipopolysaccharide. The 36th Norwegian Biochemical Society Meeting
Lecture

Flo, Trude Helen; Halaas, Øyvind; Dybdal, Brit; Torp, Sverre Helge; Lien, Egil; Miyake, Kensuke; Golenbock, Douglas T.; Sundan, Anders; Espevik, Terje. (2000) Expression and functions of toll-like receptor 2. The 8th International TNF Congress
Conference poster

Flo, T.H.; Halaas, Ø.; Dybdahl, B.; Torp, S.H.; Lien, E.; Mikyake, K.; Golenbock, D.; Sundan, A.; Espevik, Terje. (2000) Expression and functions of Toll like receptor 2. 8th International TNF Congress

1998

Conference poster

Flo, Trude Helen. (1998) CD14 and CR3 on monocytes are involved in TNF-production induced by detoxified LPS and mannuronic acid polymers attached to particles. 5th Conference of the International Endotoxin Society
Conference poster

Flo, Trude Helen. (1998) CD14 and CR3 on monocytes are involved in TNF-production induced by detoxified LPS and mannuronic acid polymers attached to particles. Norsk Biokjemisk Selskaps 34. møte

Språkvelger

Trude Helen Flo

Trude Helen Flo

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C-LUNG: Childrens lung study in Dhulikhel, Nepal

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