Wiebke Häger
About
I am a biochemist with a special interest in plant cell wall degrading enzymes (PCWDEs), particularly those enzymes that target the plant cell wall polysaccharide pectin.
In 2021, I obtained my PhD in Yannick Pauchet’s group “Molecular Biology of the Insect Digestive System” at the Max Planck Institute for Chemical Ecology. There, I studied how inhibitory proteins from the plant cell wall influenced the pectin digestion system of herbivorous beetles.
Currently, I am working as a Postdoctoral Researcher in Thorsten Hamann’s group “Functional Plant Biology” in the Multiscale Biology section of the Department of Biology. Focusing on the model organism Arabidopsis thaliana, the Hamann Lab studies cell wall integrity (CWI) maintenance in plants. The CWI maintenance mechanism comprises a complex network of proteins and signalling events that monitor the state of the cell wall and integrate the information into plant responses to ensure the integrity of the plant cell. CWI can be influenced by external stressors (e.g., drought, salinity or pathogen attacks) or internal cues (e.g. cell wall remodelling during development).
PCWDEs are produced by both, phytopathogens and plants themselves. In my project, I am interested how plants perceive changes in the cell wall and CWI caused by PCWDEs and if plants differentiate between changes in CWI that was caused by internal or external factors.
Teaching
I am involved in the following courses:
BI2015 – Molecular Biology, Lab Course
BI3013 – Experimental Cell- and Molecular Biology
BI2012 – Cell Biology, Lab Course
BI1007 – The Structure and Function of Plants
BI2080 – Global Change Biology
REFL3080 – Scientific Research Seminar in Natural Resource Management
Background
since 2022 – Postdoctoral Researcher, Research Group “Functional Plant Biology”, Norwegian University of Science and Technology, Trondheim, NO
2016 – 2021 – Doctoral Researcher with research topic "Biochemistry", Research Group “Molecular Biology of the Insect Digestive System”, Max Planck Institute for Chemical Ecology, Jena, DE
2013 – 2016 – M. Sc. Biochemistry, Friedrich Schiller University, Jena, DE
2010 – 2013 – B. Sc. Biochemie/Molekularbiologie, Friedrich Schiller University, Jena, DE
Publications
2022
-
Häger, Wiebke;
Pauchet, Yannick;
Kirsch, Roy.
(2022)
EVOLUTION OF POLYGALACTURONASES AND POLYGALACTURONASEINHIBITING PROTEINS: A VIEW BEYOND THE CLASSICAL PERSPECTIVE.
Annual Plant Reviews online.
Academic literature review
-
Kirsch, Roy;
Okamura, Yu;
Häger, Wiebke;
Vogel, Heiko;
Kunert, Grit;
Pauchet, Yannick.
(2022)
Metabolic novelty originating from horizontal gene transfer is essential for leaf beetle survival.
Proceedings of the National Academy of Sciences of the United States of America.
volum 119 (40).
Academic article
-
Schulz, Julia;
Heien, Hanne Alise;
Bjerkesmoen, Hedda;
Hamann, Thorsten;
Alonso Baez, Luis;
Ivanova, Anastasiia;
Häger, Wiebke;
Ticha, Tereza.
(2022)
Prøv deg som forsker.
Forskningstorget 2022
[Kunstnerisk og museal presentasjon] . NTNU, Forskningsdagene, Hyfer; Trondheim. 2022-09-23 - 2022-09-24.
Other presentation
-
Schulz, Julia;
Ticha, Tereza;
Amanda, Dhika;
Moe, Pernille Sofie;
Heien, Hanne Alise;
Bjerkesmoen, Hedda;
Hamann, Thorsten;
Häger, Wiebke;
Alonso Baez, Luis.
(2022)
Prøv deg som forsker.
Ungdommens Forskernatt 2022
[Kunstnerisk og museal presentasjon] . NTNU, Forskningsdagene, Hyfer; Trondheim. 2022-09-30.
Other presentation
2021
-
Häger, Wiebke.
(2021)
Plant-derived inhibitors targeting a beetle’s pectin digestion: A biochemical study on the interaction between plant cell wall proteins and members of the glycoside hydrolase family 28 from the mustard leaf beetle Phaedon cochleariae.
2021.
Doctoral dissertation
-
Häger, Wiebke;
Wielsch, Natalie;
Shin, Na Ra;
Gebauer-Jung, Steffi;
Pauchet, Yannick;
Kirsch, Roy.
(2021)
New Players in the Interaction Between Beetle Polygalacturonases and Plant Polygalacturonase-Inhibiting Proteins: Insights From Proteomics and Gene Expression Analyses.
Frontiers in Plant Science.
Academic article
2020
-
Häger, Wiebke;
Henning, Jana;
Heckel, David G.;
Pauchet, Yannick;
Kirsch, Roy.
(2020)
Direct evidence for a new mode of plant defense against insects via a novel polygalacturonase-inhibiting protein expression strategy.
Journal of Biological Chemistry.
Academic article
2015
-
Rahfeld, Peter;
Häger, Wiebke;
Kirsch, Roy;
Pauls, Gerhard;
Becker, Tobias;
Schulze, Eva;
Wielsch, Natalie;
Wang, Ding;
Groth, Marco;
Brandt, Wolfgang;
Boland, Wilhelm;
Burse, Antje.
(2015)
Glandular β-glucosidases in juvenile Chrysomelina leaf beetles support the evolution of a host-plant-dependent chemical defense.
Insect Biochemistry and Molecular Biology.
Academic article
Journal publications
-
Häger, Wiebke;
Pauchet, Yannick;
Kirsch, Roy.
(2022)
EVOLUTION OF POLYGALACTURONASES AND POLYGALACTURONASEINHIBITING PROTEINS: A VIEW BEYOND THE CLASSICAL PERSPECTIVE.
Annual Plant Reviews online.
Academic literature review
-
Kirsch, Roy;
Okamura, Yu;
Häger, Wiebke;
Vogel, Heiko;
Kunert, Grit;
Pauchet, Yannick.
(2022)
Metabolic novelty originating from horizontal gene transfer is essential for leaf beetle survival.
Proceedings of the National Academy of Sciences of the United States of America.
volum 119 (40).
Academic article
-
Häger, Wiebke;
Wielsch, Natalie;
Shin, Na Ra;
Gebauer-Jung, Steffi;
Pauchet, Yannick;
Kirsch, Roy.
(2021)
New Players in the Interaction Between Beetle Polygalacturonases and Plant Polygalacturonase-Inhibiting Proteins: Insights From Proteomics and Gene Expression Analyses.
Frontiers in Plant Science.
Academic article
-
Häger, Wiebke;
Henning, Jana;
Heckel, David G.;
Pauchet, Yannick;
Kirsch, Roy.
(2020)
Direct evidence for a new mode of plant defense against insects via a novel polygalacturonase-inhibiting protein expression strategy.
Journal of Biological Chemistry.
Academic article
-
Rahfeld, Peter;
Häger, Wiebke;
Kirsch, Roy;
Pauls, Gerhard;
Becker, Tobias;
Schulze, Eva;
Wielsch, Natalie;
Wang, Ding;
Groth, Marco;
Brandt, Wolfgang;
Boland, Wilhelm;
Burse, Antje.
(2015)
Glandular β-glucosidases in juvenile Chrysomelina leaf beetles support the evolution of a host-plant-dependent chemical defense.
Insect Biochemistry and Molecular Biology.
Academic article
Report
-
Häger, Wiebke.
(2021)
Plant-derived inhibitors targeting a beetle’s pectin digestion: A biochemical study on the interaction between plant cell wall proteins and members of the glycoside hydrolase family 28 from the mustard leaf beetle Phaedon cochleariae.
2021.
Doctoral dissertation
UTSTILLING
-
Schulz, Julia;
Heien, Hanne Alise;
Bjerkesmoen, Hedda;
Hamann, Thorsten;
Alonso Baez, Luis;
Ivanova, Anastasiia;
Häger, Wiebke;
Ticha, Tereza.
(2022)
Prøv deg som forsker.
Forskningstorget 2022
[Kunstnerisk og museal presentasjon] . NTNU, Forskningsdagene, Hyfer; Trondheim. 2022-09-23 - 2022-09-24.
Other presentation
-
Schulz, Julia;
Ticha, Tereza;
Amanda, Dhika;
Moe, Pernille Sofie;
Heien, Hanne Alise;
Bjerkesmoen, Hedda;
Hamann, Thorsten;
Häger, Wiebke;
Alonso Baez, Luis.
(2022)
Prøv deg som forsker.
Ungdommens Forskernatt 2022
[Kunstnerisk og museal presentasjon] . NTNU, Forskningsdagene, Hyfer; Trondheim. 2022-09-30.
Other presentation