course-details-portlet

KJ3021

Nuclear Magnetic Resonance Spectroscopy

Credits 7.5
Level Second degree level
Course start Autumn 2020
Duration 1 semester
Language of instruction English
Location Trondheim
Examination arrangement Home examination

About

About the course

Course content

The course presents an overview of the principles of modern NMR spectroscopy and its application within organic chemistry. NMR puls techniques are presented. Various 1D experiments are discussed, including double resonance and those consisting of complex pulse sequences. Two-dimensional experiments and applications on static and dynamic structure determinations are reviewed. Selected examples of published applications are discussed.

Learning outcome

After having completed the course, the student should be able to:

1. Explain the basic principles of NMR at an advanced level.
2. Explain the concepts of 1D and 2D NMR experiments.
3. Show the effect of basic pulse sequences on macroscopic magnetization by applying Bloch's vector model.
4. Show and explain function of the main units of an NMR instrument.
5. Prepare a sample for an NMR experiment.
6. Operate an NMR instrument: run a standard 1H 1D NMR experiment.
7. Acquire and process 1D and 2D NMR data by using TopShim software.
8. Analyze spectra using the same software and interpret them.
9. Elucidate structure of an unknown compound from a set of NMR spectra.
10. Design the most suitable NMR experiment setup for addressing a particular structure-related problem.

Learning methods and activities

Lectures (2 hours per week) and exercises (3 hours per week). Lectures and exercises are in English. The examination paper will only be given in English, and the answers have to be given in English as well.
For re-sit exam or exam during a term without lectures in this course, written examination may be changed to oral examination.

Further on evaluation

In case of a re-sit examination only the written exam is repeated.

Course materials

H. Friebolin: Basic One- and Two-Dimensional NMR Spectroscopy, 5. ed., Wiley-VCH, 2011. E. Breitmaier: Structure Elucidation by NMR in Organic Chemistry, 3. ed., Wiley, 2002.

Credit reductions

Course code Reduction From
MNKKJ321 7.5 sp
MNKKJ321 7.5 sp
TKJ4120 7.5 sp
KJ3022 7.5 sp
This course has academic overlap with the courses in the table above. If you take overlapping courses, you will receive a credit reduction in the course where you have the lowest grade. If the grades are the same, the reduction will be applied to the course completed most recently.

Subject areas

  • Organic Chemistry
  • Chemistry

Contact information

Course coordinator

Department with academic responsibility

Department of Chemistry

Examination

Examination

Examination arrangement: Home examination
Grade: Letters

Ordinary examination - Autumn 2020

Home exam (1)
Weighting 100/100 Date Release 2020-12-19
Submission 2020-12-19 Time Release 09:00
Submission 12:00 Duration 3 hours Exam system Inspera Assessment
  • Other comments
  • 1) Merk at eksamensform er endret som et smittevernstiltak i den pågående koronasituasjonen. Please note that the exam form has changed as a preventive measure in the ongoing corona situation

Ordinary examination - Spring 2021

Home exam (2)
Weighting 100/100 Date Release 2021-05-27
Submission 2021-05-27 Time Release 09:00
Submission 12:00 Duration 3 hours Exam system Inspera Assessment
  • Other comments
  • 2) Merk at eksamensform er endret som et smittevernstiltak i den pågående koronasituasjonen. Please note that the exam form has changed as a preventive measure in the ongoing corona situation.

All about examinations at NTNU