TFY4310 - Molecular Biophysics


Examination arrangement

Examination arrangement: Portfolio assessment
Grade: Letters

Evaluation form Weighting Duration Examination aids Grade deviation
work 20/100
Written examination 80/100 4 hours C

Course content

The course focuses on the application of selected topics within physics to describe the molecular properties of biological molecules and biopolymer assemblies, and some of the most commonly used techniques for the determination of these properties.

Learning outcome

A student that has successfully completed the course has obtained knowledge within:

(i) the main types of intramolecular and intermolecular interactions;

(ii) molecular theories used for the description of polymers and their physical properties, phase stability of polymer solutions, and deformation and swelling of polymer and polyelectrolyte networks;

(iii) the self-assembly behavior of amphiphilic molecules in aqueous solution;

(iv) the underlying theory for the most important techniques used to study the physical, thermodynamic, hydrodynamic, spectroscopic and scattering properties.

A student that has successfully completed the course has acquired the following skills:

(i) discuss how intramolecular and intermolecular interactions affect (a) the conformation and dynamic properties of macromolecules, and (b) the interactions between macromolecules and other solutes in aqueous solution;

(ii) application of the relevant molecular theories to describe physical properties of polymers with emphasis on biomacromolecules such as proteins, polysaccharides and nucleic acids;

(iii) relate the structural properties of amphiphilic molecules with the properties of the formed phases;

(iv) evaluate and discuss the applicability of the studied techniques to a variety of biophysical systems.

(v) operate selected instrumental set-ups and molecular modeling packages, interpret and critically evaluate the obtained data, and summarize the results in a written report.

A student that has successfully completed the course has enhanced their general competence in:
- preparation and execution of lab exercises, written presentation of results and critical discussion.

Learning methods and activities

Lectures, problem solving and laboratory exercises. Expected work load in the course is 225 hours.

Compulsory assignments

  • Laboratory exercises
  • Problem solving

Further on evaluation

Portfolio assessment is the basis for the grade in the course. The portfolio includes a final written exam (80%) and problem solving (20%). The results for the different parts are given in %-scores, while the entire portfolio is assigned a letter grade.
The re-sit examination (in August) may be changed from written to oral.
For a re-take of an examination, all assessments in the portfolio must be re-taken.
The exam may be given in English only.

Specific conditions

Exam registration requires that class registration is approved in the same semester. Compulsory activities from previous semester may be approved by the department.

Course materials

Elgsæter, Mikkelsen, Næss, and Dias: Molecular Biophysics, compendium.

Credit reductions

Course code Reduction From To
SIF4090 7.5
FY8911 7.5 01.09.2017
TFY4335 3.0 01.09.2020
More on the course

Version: 1
Credits:  7.5 SP
Study level: Second degree level


Term no.: 1
Teaching semester:  AUTUMN 2020

No.of lecture hours: 4
Lab hours: 1
No.of specialization hours: 7

Language of instruction: English

Location: Trondheim

Subject area(s)
  • Biophysics and Medical Technology
  • Biophysics
  • Physics
Contact information
Course coordinator: Lecturer(s):

Department with academic responsibility
Department of Physics



Examination arrangement: Portfolio assessment

Term Status code Evaluation form Weighting Examination aids Date Time Digital exam Room *
Autumn ORD work 20/100
Room Building Number of candidates
Autumn ORD Written examination 80/100 C
Room Building Number of candidates
  • * The location (room) for a written examination is published 3 days before examination date. If more than one room is listed, you will find your room at Studentweb.

For more information regarding registration for examination and examination procedures, see "Innsida - Exams"

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