TFY4335 - Nano Life Science

About

Examination arrangement

Examination arrangement: Written examination
Grade: Letters

Evaluation form Weighting Duration Examination aids Grade deviation
Written examination 100/100 4 hours C

Course content

Structure of biological molecules with special focus on molecular shape, structure formation, bio-recognition properties and self-assembly. Biophysics important for bionanotechnology, design of bionanosensors and micorfluidic devices. Brownian motion, diffusion, transport, intermolecular interactions, coopterativ transitions and properties of single polymer chains, molecular machines and molecular motors, science and science-fiction of nano-robots. Principles and challenges for applications of biological molecules and biological processes in sensors and devices including nanobiosensors, interaction between cells and electronic components, micro- and nano-fluidics devices. Current applications of bionanotechnology.

Learning outcome

After complition of the course, student should be able to:
(1) describe various processes important for understanding cellular functions using simplified physical models. In particular, understand physical forces needed to understand and describe intermolecular interactions and the role of entropy; electrostatic interactions in solution, entropic forces, transport phenomena like diffusion and the role of Brownian motion.
(2) know how to describe, model and measure mechanical properties of single polymer chains and inetrmolecular interactions; understand how inter- and intramolecular interactions influence mechanical properties of bio-polymers, proteins and nucleic acids.
(3) understand properties of water at micro- and nanometer scales important for cellular functions and design of biosensors; understand the concept of microfluidic devices and physical phenomena important in their function. Be able to design and make simple microfluidic devices.
(4) understand how living organisms convert chemical energy into mechanical work
(5) implement some of the physical models discussed in the course in computer simulations in Matlab.

Learning methods and activities

Lectures, problem classes and laboratory exercises with report writing. All reports must be approved to be admitted to the exam. When lectures and lecture material are in English, the exam may be given in English only.

Compulsory assignments

  • Laboratory exercises

Further on evaluation

The re-sit examination (in August) may be changed from written to oral.

Specific conditions

Exam registration requires that class registration is approved in the same semester. Compulsory activities from previous semester may be approved by the department.

Course materials

Main textbook: Physical Biology of the Cell. Rob Phillips, Jane Kondev, Julie Theriot, Hernan Garcia. ISBN: 9780815344506.
Additional materials: To be announced at the start of the semester.

Credit reductions

Course code Reduction From To
TFY4310 7.5 2015-09-01

Timetable

Detailed timetable

Examination

Examination arrangement: Written examination

Term Statuskode Evaluation form Weighting Examination aids Date Time Room *
Autumn ORD Written examination 100/100 C 2017-12-02 09:00
  • * The location (room) for a written examination is published 3 days before examination date.
If more than one room is listed, you will find your room at Studentweb.