course-details-portlet

TKJ4102 - Basic Organic Chemistry

About

Examination arrangement

Examination arrangement: Portfolio assessment
Grade: Letters

Evaluation form Weighting Duration Examination aids Grade deviation
Semester test 20/100 2 hours C
Home examination 80/100 4 hours

Course content

Basic organic chemical concepts, such as chemical structures and nomenclature, physical properties, stereochemistry and relationship between structure and reactivity will be presented. Reaction mechanisms will be presented to give insight in chemical transformations. Alkanes and cycloalkanes: Conformations and cis-trans stereoisomers. Stereochemistry: Geometric isomers, conformation isomers, configuration isomers and pro-chirality. Absolute and relative configuration, R/S notational system for chiral C-atoms, optical activity (specific rotation), enantiomers, diastereomers, meso compounds, three-dimensional projections of molecule´s atoms, stereochemistry in chemical reactions. Alcohols and alkyl halides: Substitution (SN1/SN2), elimination (E1/E2), potential energy diagrams for multiple step reactions, carbocations and rearrangements. Nucleophilic substitution (SN2): Nucleophilic reagents, nucleophilicity versus basicity, solvent effects, leaving group, functionalization and stereochemistry. Structure and preparation of alkenes: Elimination reactions. Addition reactions of alkenes: (i) Hydrogenation, (ii) electrophilic addition of hydrogen halides (Markovnikov's rule and mechanism), (iii) acid-catalyzed hydration, i(v) hydroboration-oxidation to alcohols (anti-Markovinkov), (v) epoxidation. Alkynes: Preparation, acid-base properties, alkylation of terminal alkynes. Addition reactions of alkynes. Alcohols: Preparation by (i) reduction of carbonyl compounds, (ii) ring opening of epoxides, (iii) dihydroxylation of alkenes. Reactions of alcohols: (i) Preparation of ethers, (ii) preparation of esters and (iii) oxidation to aldehyde/carboxylic acid/ketone. Grignard reagents and organolitium (organometallic compounds): Preparation, reactivity and reactions (base and addition to carbonyl compounds). Conjugation in alkadienes and allylic systems, allylic carbocations, resonance (electron delocalization), stability, isolated dienes, conjugated dienes, cumulated dienes. Conjugated dienes: (i) Preparation, (ii) addition of hydrogen halide, The Diels-Alder reaction. Arenes and aromaticity. Reactions of arenes: Electrophilic aromatic substitution. Radical halogenation of alkylbenzenes. Aldehydes and ketones: (i) Structure and reactivity, (ii) The Wittig reaction, (iii) preparation of imine, (iv) acetal formation, (v) enols and enolates, (vi) alkylation of enolates, (vii) aldol condensation. Carboxylic acids: (i) Acidity, (ii) preparation and (iii) reactions (ester formation). Carboxylic acid derivatives: (i) Esters, (ii) acid anhydrides, (iii) acid halides. Hydrolysis of carboxylic acid derivatives. Interpretation of simple proton NMR spectra.

Learning outcome

After completing this course the student will, in relation to the content of the subject: (i) be able to understand and communicate nomenclature and structure of organic chemical compounds, (ii) know basic principles for reactions in organic chemistry, (iii) be able to account for and derive mechanistic features of the reactions, (iv) be able to predict competing reactions, (v) be able to name central reactions, (vi) have a basic knowledge of how functional groups affect electron density, properties and reactivity in organic compounds, (vii) be able to estimate pKa values for carboxylic acids, amines, alcohols and ketones in the presence of different functional groups. Interpretation of simple proton NMR spectra.

Learning methods and activities

TKJ4102 is the theoretical course in basic organic chemistry for students enrolled in the Ms. Tech. program. TKJ4102 consists of lectures (4 hours per week) and exercises (2 hours per week). 67% of the exercises must be approved by submission of answers in WileyPLUS digital learning platform.

Compulsory assignments

  • Minimum 67% approved exercises

Further on evaluation

The final grade is based on portfolio assessment. The portfolio includes written exam (80%) and semester assignment (20%). The evaluation of the different parts is given in %-points, while the entire portfolio is given a letter grade.
The re-sit examination may be changed from written to oral. When the exam is repeated the semester assingnment (the mid-term exam) must be repeated.

Specific conditions

Exam registration requires that class registration is approved in the same semester. Compulsory activities from previous semester may be approved by the department.

Course materials

Solomons, Fryhle, Snyder: "Organic chemistry", 12th ed. Wiley, 2017.
Compulsory exercises require access (purchase) of code to WileyPLUS digital learning with digital textbook, reaction videos, exercises and ORION self-training tools.

Credit reductions

Course code Reduction From To
TKJ4100 7.5 01.09.2010
KJ1020 7.5 01.09.2010
TBT4160 3.7 01.09.2010
SIK3020 7.5 01.09.2010
HBIO1005 3.5 01.09.2019
HBIO2007 3.5 01.09.2019
MK101309 3.5 01.09.2019
TKJE2001 7.5 01.09.2019
TMAT1009 7.5 01.09.2019
KJ1022 6.0 01.09.2020
More on the course

No

Facts

Version: 1
Credits:  7.5 SP
Study level: Intermediate course, level II

Coursework

Term no.: 1
Teaching semester:  AUTUMN 2020

No.of lecture hours: 4
Lab hours: 2
No.of specialization hours: 6

Language of instruction: Norwegian

Location: Trondheim

Subject area(s)
  • Organic Chemistry
  • Chemistry
Contact information
Course coordinator:

Department with academic responsibility
Department of Chemistry

Phone:

Examination

Examination arrangement: Portfolio assessment

Term Status code Evaluation form Weighting Examination aids Date Time Digital exam Room *
Autumn ORD Semester test 20/100 C
Room Building Number of candidates
Autumn ORD Home examination 80/100

Release 2020-12-09

Submission 2020-12-09

Release 15:00

Submission 19:00

INSPERA
Room Building Number of candidates
  • * The location (room) for a written examination is published 3 days before examination date. If more than one room is listed, you will find your room at Studentweb.
Examination

For more information regarding registration for examination and examination procedures, see "Innsida - Exams"

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