Anne Mari A. Rokstad

About

Profile

Associate Professor in Human Toxicology with a focus on immunocompatibility, inflammation, and biomaterial–host interactions. Her research spans immune responses to biomaterials, endogenous structures such as cholesterol crystals, and exogenous micro‑ and nanoparticles, with relevance to metabolic and cardiovascular disease. She works translationally across mechanistic immunology, immunotoxicology, and clinical collaboration with St. Olavs Hospital.

Research Areas

Immunocompatibility and immunotoxicology
Biomaterials, micro‑ and nanoparticles
Innate immunity and inflammatory mechanisms
Complement and coagulation
Translational inflammation
Cell encapsulation technologies
Inflammation in metabolic and cardiovascular disease

Research

My research aims to understand and predict immune and inflammatory responses to biomaterials and particulate structures, ranging from clinically applied materials to environmental micro‑ and nanoplastics.

Core themes include:

Immune reactions toward exogenous and endogenous materials, including micro‑ and nanoplastics
Mechanisms of complement and coagulation activation
Translational testing models integrating whole blood assays, molecular analyses, cell‑based systems, and in vivo models
Inflammatory implications in obesity, diabetes, and cardiovascular disease
Development of safer biomaterials and infusion therapies

Current projects involve cross‑disciplinary collaborations between NTNU and St. Olavs Hospital, and international partners.

Selected Projects (Ongoing and Recent)

2026–2028 – PI, Safer Infusion Therapy through Immunotoxicology and Clinical Integration
2025–2026 – PI, Plastic Health Biobank
2023–2025 – PI, Environmental Micro- and Nanoplastics and Human Health
2021–2024 – Co‑PI, Tailored Biomaterials with Reduced Immune Responses
2019–2021 – PI, Biocompatibility Testing Using Patients with Type 1 Diabetes

(Full project list available upon request.)

Teaching and supervision

I teach in the medical curriculum, primarily in human toxicology and immunotoxicology, and contribute to teaching activities across toxicology, immunology, and molecular medicine. I lecture in Medicine (MD4012, MD4020), as well as in MOL3018, MOL3005, MOL3015, and MOL8009. I supervise MSc and PhD students and have extensive experience guiding master’s students in Molecular Medicine, Biotechnology, Pharmacy, and Nanomedicine through experimental, translational, and interdisciplinary research projects.

Research

Inflammation is a fundamental defence mechanism involved in responses to foreign invaders as well as in endogenous processes such as wound healing. It is increasingly recognized as a central driver in a wide range of diseases. Inflammatory reactions arise from complex communication between cellular and protein components of the immune system, and the specific pathways engaged depend on the type of disturbance. Understanding these mechanisms is essential for revealing disease development, identifying therapeutic targets, and improving human health.

A major focus of my research is to elucidate inflammatory mechanisms triggered by both exogenous and endogenous materials. Exogenous materials may be intentionally used, such as biomaterials and micro‑ or nanomaterials in medical applications, or they may arise from unintentional exposure, including micro‑ and nanoplastics encountered in daily life. Endogenous materials, in contrast, are produced within the body and include structures such as cholesterol crystals formed in atherosclerotic plaques.

Although these materials differ in origin and properties, they interact with the immune system through both shared and distinct pathways. The overarching aim of my research is to understand immune and inflammatory processes at the interface of material exposure and to use this knowledge to promote improved health outcomes.

Current research projects investigate how material properties shape inflammatory patterns, with emphasis on biomaterial design and cholesterol‑crystal‑induced inflammation relevant to cardiovascular disease. A recently established project focuses on micro‑ and nanoplastics and their impact on blood immune responses.

In parallel with these activities, my research also addresses immune and inflammatory responses in metabolic diseases such as obesity and diabetes.

For many years, I have additionally been part of an international research network working toward the development of long‑term, fibrosis‑free biodevices for cell therapy in the treatment of Type 1 diabetes.

Chicago Diabetes Project

Tailored Biomaterials for Reduced Immune Response

Collaboration among experts in biopolymers, biomaterials, immunology and proteomics to clarify how biomaterial design directs host proteins and immune responses. This insight is key to developing functional biomaterials.

Publications

Type 1 diabetes mellitus (T1DM) does not affect whole blood responses to alginate-based microspheres despite plasma lipid and glucose differences

First study to investigate initial inflammatory capacity between T1DM and controls towards biomaterials, bioparticles and TLR ligands. We find that these responses are similar despite identifying metabolic differences in lipoproteins and metabolites.

MS-proteomics provides insight into the host responses towards alginate microspheres

First study to map host proteins of various alginate microspheres of relevance in cell therapy. Study find differences to inflammatory pathways. Fibrosis free microspheres bind naturally and enrich for anti-complement and anti-coagulation proteins.

Cholesterol crystals induce coagulation activation through complement-dependent expression of monocytic tissue factor

Study showing a link between cholesterol crystals and coagulation activation. Cholesterol crystals found in atherosclerotic plaques could be contributors in thrombosis.

2025

Vasuthas, Kalaiyarasi; Christiansen, Sverre Christian; Kjesbu, Joachim Sebastian; Ryan, Liv; Andreassen, Trygve; Slupphaug, Geir. (2025) Type 1 diabetes mellitus (T1DM) does not affect whole blood responses to alginate-based microspheres despite plasma lipid and glucose differences. Materials Today Bio
Academic article
Lundanes, Julianne; Nes, Vilde Fiske; Aakervik, Oda; Ryan, Liv; Hansson, Patrik; Rokstad, Anne Mari A.. (2025) Changes in Cytokines and Fibrotic Growth Factors after Low-Carbohydrate or Low-Fat Low-Energy Diets in Females with Lipedema. Current Developments in Nutrition (CDN)
Academic article
Vasuthas, Kalaiyarasi; Kjesbu, Joachim Sebastian; Brambilla, Alessandro; Levitan, Maya; Coron, Abba Elizabeth; Fonseca, Davi de Miranda. (2025) Fucoidan alginate and sulfated alginate microbeads induce distinct coagulation, inflammatory and fibrotic responses. Materials Today Bio
Academic article

2024

Dorchei, F.; Heydari, Abolfazl; Kronekovà, Zuzana; Kronek, Juraj; Pelach, Michal; Cseriovà, Zuzana. (2024) Postmodification with Polycations Enhances Key Properties of Alginate-Based Multicomponent Microcapsules. Biomacromolecules
Academic article
Bright, Richard; Visalakshan, Rahul M.; Simon, Johanna; Rokstad, Anne Mari A.; Ghazaryan, Arthur; Morsbach, Svenja. (2024) Manipulation of Serum Protein Adsorption by Nanoengineered Biomaterials Influences Subsequent Immune Responses. ACS Biomaterials Science and Engineering
Academic article
Widerøe, Marius; Falkenberg, Liv Eggset; Cyvin, Jakob Bonnevie; Richter, Isabell; Klingsheim, Karl; Rokstad, Anne Mari A.. (2024) Verdens plastproblem - går det på helsa løs?. Norges teknisk-naturvitenskapelige universitet Norges teknisk-naturvitenskapelige universitet
Report

2022

Coron, Abba Elizabeth; Fonseca, Davi de Miranda; Sharma, Animesh; Slupphaug, Geir; Strand, Berit Løkensgard; Rokstad, Anne Mari A.. (2022) MS-proteomics provides insight into the host responses towards alginate microspheres. Materials Today Bio
Academic article
Syanda, Adam M.; Kringstad, Vera I.; Blackford, Samuel J.I.; Kjesbu, Joachim Sebastian; Ng, Soon Seng; Ma, Liang. (2022) Sulfated alginate reduces pericapsular fibrotic overgrowth on encapsulated cGMP-compliant hPSC-hepatocytes in mice. Frontiers in Bioengineering and Biotechnology
Academic article

2021

Coron, Abba E.; Kjesbu, Joachim Sebastian; Kjærnsmo, Fredrikke; Oberholzer, José; Rokstad, Anne Mari A.; Strand, Berit Løkensgard. (2021) Pericapsular fibrotic overgrowth mitigated in immunocompetent mice through microbead formulations based on sulfated or intermediate G alginates. Acta Biomaterialia
Academic article

2020

Niyonzima, Nathalie; Bakke, Siril Skaret; Gregersen, Ida; Holm, Sverre; Sandanger, Øystein; Orrem, Hilde Lang. (2020) Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis. EBioMedicine
Academic article

2019

Nordli, Henriette R.; Pukstad, Brita; Chinga-Carrasco, Gary; Rokstad, Anne Mari. (2019) Ultrapure Wood Nanocellulose - Assessments of Coagulation and Initial Inflammation Potential. ACS Applied Bio Materials (AABM)
Academic article
Gravastrand, Caroline S.; Steinkjer, Bjørg; Halvorsen, Bente; Landsem, Anne; Skjelland, Mona; Jacobsen, Eva Astrid. (2019) Cholesterol Crystals Induce coagulation Activation through Complement-Dependent Expression of Monocytic Tissue Factor. Journal of Immunology
Academic article

2018

Bochenek, Matthew A.; Veiseh, Omid; Vegas, Arturo J.; McGarrigle, James J.; Qi, Meirigeng; Marchese, Enza. (2018) Alginate encapsulation as long-term immune protection of allogeneic pancreatic islet cells transplanted into the omental bursa of macaques. Nature Biomedical Engineering
Academic article
Kopplin, Georg; Rokstad, Anne Mari; Mélida, Hugo; Bulone, Vincent; Skjåk-Bræk, Gudmund; Aachmann, Finn Lillelund. (2018) Structural characterization of fucoidan from Laminaria hyperborea: Assessment of coagulation and inflammatory properties and their structure−function relationship. ACS Applied Bio Materials (AABM)
Academic article

2017

Wolf-Grosse, Susann; Rokstad, Anne Mari; Ali, Syed; Lambris, JD; Mollnes, Tom Eirik; Nilsen, Asbjørn Magne. (2017) Iron oxide nanoparticles induce cytokine secretion in a complement-dependent manner in a human whole blood model. International Journal of Nanomedicine
Academic article
Gravastrand, Caroline; Hamad, Shamal; Fure, Hilde; Steinkjer, Bjørg; Ryan, Liv; Oberholzer, José. (2017) Alginate microbeads are coagulation compatible, while alginate microcapsules activate coagulation secondary to complement or directly through FXII. Acta Biomaterialia
Academic article
Vaithilingam, Vijayaganapathy; Steinkjer, Bjørg; Ryan, Liv; Larsson, Rolf; Tuch, Bernard E.; Oberholzer, José. (2017) In Vitro and In Vivo Biocompatibility Evaluation of Polyallylamine and Macromolecular Heparin Conjugates Modified Alginate Microbeads. Scientific Reports
Academic article

2016

Arlov, Øystein; Skjåk-Bræk, Gudmund; Rokstad, Anne Mari. (2016) Sulfated alginate microspheres associate with factor H and dampen the inflammatory cytokine response. Acta Biomaterialia
Academic article
Nordli, Henriette R.; Chinga-Carrasco, Gary; Rokstad, Anne Mari; Pukstad, Brita. (2016) Producing ultrapure wood cellulose nanofibrils and evaluating the cytotoxicity using human skin cells. Carbohydrate Polymers
Academic article
Ørning, Mathias Pontus; Hoem, Kine Samset; Coron, Abba Elizabeth; Skjåk-Bræk, Gudmund; Mollnes, Tom Eirik; Brekke, Ole Lars. (2016) Alginate microsphere compositions dictate different mechanisms of complement activation with consequences for cytokine release and leukocyte activation. Journal of Controlled Release
Academic article

2015

Niyonzima, Nathalie; Samstad, Eivind; Aune, Marie Hjelmseth; Ryan, Liv; Bakke, Siril Skaret; Rokstad, Anne Mari. (2015) Reconstituted high-density lipoprotein attenuates cholesterol crystal-induced inflammatory responses by reducing complement activation. Journal of Immunology
Academic article

2014

Sandvig, Ioanna; Karstensen, Kristin; Rokstad, Anne Mari; Aachmann, Finn Lillelund; Formo, Kjetil Ødegård; Sandvig, Axel. (2014) RGD-peptide modified alginate by a chemoenzymatic strategy for tissue engineering applications. Journal of Biomedical Materials Research. Part A
Academic article
Rokstad, Anne Mari; Lacík, Igor; DeVos, Paul; Strand, Berit Løkensgard. (2014) Advances in biocompatibility and physico-chemical characterization of microspheres for cell encapsulation. Advanced Drug Delivery Reviews
Academic literature review

2013

Hals, Ingrid Katrin; Rokstad, Anne Mari; Strand, Berit Løkensgard; Oberholzer, José; Grill, Valdemar. (2013) Alginate Microencapsulation of Human Islets Does Not Increase Susceptibility to Acute Hypoxia. Experimental Diabetes Research
Academic article
Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Strand, Berit Løkensgard. (2013) The induction of cytokines by polycation containing microspheres by a complement dependent mechanism. Biomaterials
Academic article
Hals, Ingrid Katrin; Rokstad, Anne Mari; Strand, Berit Løkensgard; Grill, Valdemar. (2013) Acute hypoxia impacts similarly on encapsulated and non-encapsulated human pancreatic islets. Diabetologia
Abstract
Rokstad, Anne Mari; Strand, Berit Løkensgard; Espevik, Terje; Mollnes, Tom Eirik. (2013) Biocompatibility and Biotolerability Assessment of Microspheres Using a Whole Blood Model. Micro and Nanosystems
Academic article

2012

Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Lambris, John D.. (2012) Poly-cation containing alginate microcapsules induce cytokines by a complement-dependent mechanism. Immunobiology
Abstract
Rokstad, Anne Mari; Gustafsson, Björn; Espevik, Terje; Bakke, Ingunn; Pfragner, Roswitha; Svejda, Bernhard. (2012) Microencapsulation of small intestinal neuroendocrine neoplasm cells for tumor model studies. Cancer Science
Academic article

2011

Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Strand, Berit Løkensgard. (2011) Alginate microbeads are complement compatible, in contrast to polycation containing microcapsules, as revealed in a human whole blood model. Acta Biomaterialia
Academic article

2009

Espevik, Terje; Rokstad, Anne Mari; Kulseng, Bård Eirik; Strand, Berit Løkensgard; Skjåk-Bræk, Gudmund. (2009) Mechanisms of the host immune response to alginate microcapsules.
Chapter

2006

Rokstad, Anne Mari Aukan; Donati, Ivan; Borgogna, Massimiliano; Oberholzer, José; Strand, Berit Løkensgard; Espevik, Terje. (2006) Cell-compatible covalently reinforced beads obtained from a chemoenzymatically engineered alginate. Biomaterials
Academic article
Rokstad, Anne Mari Aukan. (2006) Alginate capsules as bioreactors for cell therapy. Norges teknisk-naturvitenskapelige universitet Doktoravhandlinger ved NTNU, 1503-8181 (2006:24)
Doctoral dissertation

2005

Rokstad, Anne Mari Aukan; Bjerkvig, Rolf; Espevik, Terje; Lund-Johansen, M. (2005) Applications of Cell Immobilisation Biotechnology, Focus on Biotechnology. Book chapter: Cell encapsulation therapy for malignant gliomas. Springer Springer
Academic anthology/Conference proceedings

2003

Rokstad, Anne Mari Aukan; Strand, Berit Løkensgard; Rian, K.; Steinkjer, Bjørg; Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund. (2003) Evaluation of different types of alginate microcapsules as bioreactors for producing endostatin. Cell Transplantation
Academic article
King, Aileen; Strand, Berit Løkensgard; Rokstad, Anne Mari Aukan; Andersson, Arne; Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund. (2003) Improvement of the biocompatibility of alginate/poly-L-lysine/alginate microcapsules by the use of epimerized alginate as a coating. Journal of Biomedical Materials Research
Academic article

2002

Rokstad, Anne Mari Aukan; Holtan, Synnøve; Strand, Berit Løkensgard; Steinkjer, Bjørg; Ryan, Liv; Kulseng, Bård Eirik. (2002) Microencapsulation of cells producing therapeutic proteins: Optimizing cell growth and secretion. Cell Transplantation
Academic article

2001

Rokstad, Anne Mari Aukan; Kulseng, Bård Eirik; Strand, Berit Løkensgard; Skjåk-Bræk, Gudmund; Espevik, Terje. (2001) Transplantation of alginate microcapsules with proliferating cells in mice. Capsular overgrowth and suvival of encapsulated cells of mice and human origin. Annals of the New York Academy of Sciences
Academic article
Strand, Berit Løkensgard; Ryan, Liv; Veld, Peter Int; Kulseng, Bård Eirik; Rokstad, Anne Mari Aukan; Skjåk-Bræk, Gudmund. (2001) Poly-L-Lysine Induces Fibrosis on Alginate Microcapsules via the Induction of Cytokines. Cell Transplantation
Academic article
Read, Tracy-Ann; Farhadi, Mohammed; Bjerkvig, Rolf; Olsen,, Bjørn Reino; Rokstad, Anne Mari; Huszthy, Peter Csaba. (2001) Intravital microscopy reveals novel antivascular and antitumor effects of endostatin delivered locally by alginate-encapsulated cells. Cancer Research
Academic article

2000

Rokstad, Anne Mari Aukan; Skjermo, Jorunn; Skjåk-Bræk, Gudmund; Vadstein, Olav. (2000) Makrofagstudier hos piggvar og kveite etter immunstimulering med FMI in vitro og in vivo. SINTEF fiskeri og havbruk SINTEF fiskeri og havbruk
Report

Journal publications

Vasuthas, Kalaiyarasi; Christiansen, Sverre Christian; Kjesbu, Joachim Sebastian; Ryan, Liv; Andreassen, Trygve; Slupphaug, Geir. (2025) Type 1 diabetes mellitus (T1DM) does not affect whole blood responses to alginate-based microspheres despite plasma lipid and glucose differences. Materials Today Bio
Academic article
Lundanes, Julianne; Nes, Vilde Fiske; Aakervik, Oda; Ryan, Liv; Hansson, Patrik; Rokstad, Anne Mari A.. (2025) Changes in Cytokines and Fibrotic Growth Factors after Low-Carbohydrate or Low-Fat Low-Energy Diets in Females with Lipedema. Current Developments in Nutrition (CDN)
Academic article
Vasuthas, Kalaiyarasi; Kjesbu, Joachim Sebastian; Brambilla, Alessandro; Levitan, Maya; Coron, Abba Elizabeth; Fonseca, Davi de Miranda. (2025) Fucoidan alginate and sulfated alginate microbeads induce distinct coagulation, inflammatory and fibrotic responses. Materials Today Bio
Academic article
Dorchei, F.; Heydari, Abolfazl; Kronekovà, Zuzana; Kronek, Juraj; Pelach, Michal; Cseriovà, Zuzana. (2024) Postmodification with Polycations Enhances Key Properties of Alginate-Based Multicomponent Microcapsules. Biomacromolecules
Academic article
Bright, Richard; Visalakshan, Rahul M.; Simon, Johanna; Rokstad, Anne Mari A.; Ghazaryan, Arthur; Morsbach, Svenja. (2024) Manipulation of Serum Protein Adsorption by Nanoengineered Biomaterials Influences Subsequent Immune Responses. ACS Biomaterials Science and Engineering
Academic article
Coron, Abba Elizabeth; Fonseca, Davi de Miranda; Sharma, Animesh; Slupphaug, Geir; Strand, Berit Løkensgard; Rokstad, Anne Mari A.. (2022) MS-proteomics provides insight into the host responses towards alginate microspheres. Materials Today Bio
Academic article
Syanda, Adam M.; Kringstad, Vera I.; Blackford, Samuel J.I.; Kjesbu, Joachim Sebastian; Ng, Soon Seng; Ma, Liang. (2022) Sulfated alginate reduces pericapsular fibrotic overgrowth on encapsulated cGMP-compliant hPSC-hepatocytes in mice. Frontiers in Bioengineering and Biotechnology
Academic article
Coron, Abba E.; Kjesbu, Joachim Sebastian; Kjærnsmo, Fredrikke; Oberholzer, José; Rokstad, Anne Mari A.; Strand, Berit Løkensgard. (2021) Pericapsular fibrotic overgrowth mitigated in immunocompetent mice through microbead formulations based on sulfated or intermediate G alginates. Acta Biomaterialia
Academic article
Niyonzima, Nathalie; Bakke, Siril Skaret; Gregersen, Ida; Holm, Sverre; Sandanger, Øystein; Orrem, Hilde Lang. (2020) Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis. EBioMedicine
Academic article
Nordli, Henriette R.; Pukstad, Brita; Chinga-Carrasco, Gary; Rokstad, Anne Mari. (2019) Ultrapure Wood Nanocellulose - Assessments of Coagulation and Initial Inflammation Potential. ACS Applied Bio Materials (AABM)
Academic article
Gravastrand, Caroline S.; Steinkjer, Bjørg; Halvorsen, Bente; Landsem, Anne; Skjelland, Mona; Jacobsen, Eva Astrid. (2019) Cholesterol Crystals Induce coagulation Activation through Complement-Dependent Expression of Monocytic Tissue Factor. Journal of Immunology
Academic article
Bochenek, Matthew A.; Veiseh, Omid; Vegas, Arturo J.; McGarrigle, James J.; Qi, Meirigeng; Marchese, Enza. (2018) Alginate encapsulation as long-term immune protection of allogeneic pancreatic islet cells transplanted into the omental bursa of macaques. Nature Biomedical Engineering
Academic article
Kopplin, Georg; Rokstad, Anne Mari; Mélida, Hugo; Bulone, Vincent; Skjåk-Bræk, Gudmund; Aachmann, Finn Lillelund. (2018) Structural characterization of fucoidan from Laminaria hyperborea: Assessment of coagulation and inflammatory properties and their structure−function relationship. ACS Applied Bio Materials (AABM)
Academic article
Wolf-Grosse, Susann; Rokstad, Anne Mari; Ali, Syed; Lambris, JD; Mollnes, Tom Eirik; Nilsen, Asbjørn Magne. (2017) Iron oxide nanoparticles induce cytokine secretion in a complement-dependent manner in a human whole blood model. International Journal of Nanomedicine
Academic article
Gravastrand, Caroline; Hamad, Shamal; Fure, Hilde; Steinkjer, Bjørg; Ryan, Liv; Oberholzer, José. (2017) Alginate microbeads are coagulation compatible, while alginate microcapsules activate coagulation secondary to complement or directly through FXII. Acta Biomaterialia
Academic article
Vaithilingam, Vijayaganapathy; Steinkjer, Bjørg; Ryan, Liv; Larsson, Rolf; Tuch, Bernard E.; Oberholzer, José. (2017) In Vitro and In Vivo Biocompatibility Evaluation of Polyallylamine and Macromolecular Heparin Conjugates Modified Alginate Microbeads. Scientific Reports
Academic article
Arlov, Øystein; Skjåk-Bræk, Gudmund; Rokstad, Anne Mari. (2016) Sulfated alginate microspheres associate with factor H and dampen the inflammatory cytokine response. Acta Biomaterialia
Academic article
Nordli, Henriette R.; Chinga-Carrasco, Gary; Rokstad, Anne Mari; Pukstad, Brita. (2016) Producing ultrapure wood cellulose nanofibrils and evaluating the cytotoxicity using human skin cells. Carbohydrate Polymers
Academic article
Ørning, Mathias Pontus; Hoem, Kine Samset; Coron, Abba Elizabeth; Skjåk-Bræk, Gudmund; Mollnes, Tom Eirik; Brekke, Ole Lars. (2016) Alginate microsphere compositions dictate different mechanisms of complement activation with consequences for cytokine release and leukocyte activation. Journal of Controlled Release
Academic article
Niyonzima, Nathalie; Samstad, Eivind; Aune, Marie Hjelmseth; Ryan, Liv; Bakke, Siril Skaret; Rokstad, Anne Mari. (2015) Reconstituted high-density lipoprotein attenuates cholesterol crystal-induced inflammatory responses by reducing complement activation. Journal of Immunology
Academic article
Sandvig, Ioanna; Karstensen, Kristin; Rokstad, Anne Mari; Aachmann, Finn Lillelund; Formo, Kjetil Ødegård; Sandvig, Axel. (2014) RGD-peptide modified alginate by a chemoenzymatic strategy for tissue engineering applications. Journal of Biomedical Materials Research. Part A
Academic article
Rokstad, Anne Mari; Lacík, Igor; DeVos, Paul; Strand, Berit Løkensgard. (2014) Advances in biocompatibility and physico-chemical characterization of microspheres for cell encapsulation. Advanced Drug Delivery Reviews
Academic literature review
Hals, Ingrid Katrin; Rokstad, Anne Mari; Strand, Berit Løkensgard; Oberholzer, José; Grill, Valdemar. (2013) Alginate Microencapsulation of Human Islets Does Not Increase Susceptibility to Acute Hypoxia. Experimental Diabetes Research
Academic article
Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Strand, Berit Løkensgard. (2013) The induction of cytokines by polycation containing microspheres by a complement dependent mechanism. Biomaterials
Academic article
Hals, Ingrid Katrin; Rokstad, Anne Mari; Strand, Berit Løkensgard; Grill, Valdemar. (2013) Acute hypoxia impacts similarly on encapsulated and non-encapsulated human pancreatic islets. Diabetologia
Abstract
Rokstad, Anne Mari; Strand, Berit Løkensgard; Espevik, Terje; Mollnes, Tom Eirik. (2013) Biocompatibility and Biotolerability Assessment of Microspheres Using a Whole Blood Model. Micro and Nanosystems
Academic article
Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Lambris, John D.. (2012) Poly-cation containing alginate microcapsules induce cytokines by a complement-dependent mechanism. Immunobiology
Abstract
Rokstad, Anne Mari; Gustafsson, Björn; Espevik, Terje; Bakke, Ingunn; Pfragner, Roswitha; Svejda, Bernhard. (2012) Microencapsulation of small intestinal neuroendocrine neoplasm cells for tumor model studies. Cancer Science
Academic article
Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Strand, Berit Løkensgard. (2011) Alginate microbeads are complement compatible, in contrast to polycation containing microcapsules, as revealed in a human whole blood model. Acta Biomaterialia
Academic article
Rokstad, Anne Mari Aukan; Donati, Ivan; Borgogna, Massimiliano; Oberholzer, José; Strand, Berit Løkensgard; Espevik, Terje. (2006) Cell-compatible covalently reinforced beads obtained from a chemoenzymatically engineered alginate. Biomaterials
Academic article
Rokstad, Anne Mari Aukan; Strand, Berit Løkensgard; Rian, K.; Steinkjer, Bjørg; Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund. (2003) Evaluation of different types of alginate microcapsules as bioreactors for producing endostatin. Cell Transplantation
Academic article
King, Aileen; Strand, Berit Løkensgard; Rokstad, Anne Mari Aukan; Andersson, Arne; Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund. (2003) Improvement of the biocompatibility of alginate/poly-L-lysine/alginate microcapsules by the use of epimerized alginate as a coating. Journal of Biomedical Materials Research
Academic article
Rokstad, Anne Mari Aukan; Holtan, Synnøve; Strand, Berit Løkensgard; Steinkjer, Bjørg; Ryan, Liv; Kulseng, Bård Eirik. (2002) Microencapsulation of cells producing therapeutic proteins: Optimizing cell growth and secretion. Cell Transplantation
Academic article
Rokstad, Anne Mari Aukan; Kulseng, Bård Eirik; Strand, Berit Løkensgard; Skjåk-Bræk, Gudmund; Espevik, Terje. (2001) Transplantation of alginate microcapsules with proliferating cells in mice. Capsular overgrowth and suvival of encapsulated cells of mice and human origin. Annals of the New York Academy of Sciences
Academic article
Strand, Berit Løkensgard; Ryan, Liv; Veld, Peter Int; Kulseng, Bård Eirik; Rokstad, Anne Mari Aukan; Skjåk-Bræk, Gudmund. (2001) Poly-L-Lysine Induces Fibrosis on Alginate Microcapsules via the Induction of Cytokines. Cell Transplantation
Academic article
Read, Tracy-Ann; Farhadi, Mohammed; Bjerkvig, Rolf; Olsen,, Bjørn Reino; Rokstad, Anne Mari; Huszthy, Peter Csaba. (2001) Intravital microscopy reveals novel antivascular and antitumor effects of endostatin delivered locally by alginate-encapsulated cells. Cancer Research
Academic article

Books

Rokstad, Anne Mari Aukan; Bjerkvig, Rolf; Espevik, Terje; Lund-Johansen, M. (2005) Applications of Cell Immobilisation Biotechnology, Focus on Biotechnology. Book chapter: Cell encapsulation therapy for malignant gliomas. Springer Springer
Academic anthology/Conference proceedings

Part of book/report

Espevik, Terje; Rokstad, Anne Mari; Kulseng, Bård Eirik; Strand, Berit Løkensgard; Skjåk-Bræk, Gudmund. (2009) Mechanisms of the host immune response to alginate microcapsules.
Chapter

Report

Widerøe, Marius; Falkenberg, Liv Eggset; Cyvin, Jakob Bonnevie; Richter, Isabell; Klingsheim, Karl; Rokstad, Anne Mari A.. (2024) Verdens plastproblem - går det på helsa løs?. Norges teknisk-naturvitenskapelige universitet Norges teknisk-naturvitenskapelige universitet
Report
Rokstad, Anne Mari Aukan. (2006) Alginate capsules as bioreactors for cell therapy. Norges teknisk-naturvitenskapelige universitet Doktoravhandlinger ved NTNU, 1503-8181 (2006:24)
Doctoral dissertation
Rokstad, Anne Mari Aukan; Skjermo, Jorunn; Skjåk-Bræk, Gudmund; Vadstein, Olav. (2000) Makrofagstudier hos piggvar og kveite etter immunstimulering med FMI in vitro og in vivo. SINTEF fiskeri og havbruk SINTEF fiskeri og havbruk
Report

Teaching

Courses

Toxicology (Medicine)

Toxicology – Medicine IB
Toxicology – Medicine ID

Immunotoxicology & Immune Responses

Immunotoxicology
Allergy & Hypersensitivity Reactions
Immune System in Pregnancy

Immunology (MOL3005)

Barriers & Innate Defense
Complement System
Allergy & Hypersensitivity

Environment & Occupational Medicine

Occupational and Environmental Lung Diseases

Nanomedicine / Toxicology (MOL3015 & MOL3018)

Nanotoxicology
Biomaterials & Biocompatibility

Supervision

PhD supervision

Sofie Altermark - Thromboinflammatory effects of micro- and nanoplastics (ongoing)
Kalayarashi Vasuthas - Tailored biomaterials with reduced immune responses (ongoing)

Abba Elisabeth Coron - Alginate hydrogel beads for cell therapy. Doctoral thesis. https://ntnuopen.ntnu.no/ntnu-xmlui/handle/11250/3112831
Henriette Rogstad Nordlie - Carboxylated cellulose nanofibrils for wound healing. Doctoral thesis. https://ntnuopen.ntnu.no/ntnu-xmlui/handle/11250/2640757

Student Supervision (Short, MSc/Project Theses)

2024–2025

• Polystyrene micro/nanoplastics – thromboinflammation (MSc MolMed)
• Irregular micro/nanoplastics – inflammation (MSc Biology)

2025

• Micro/nanoplastics – coagulation & complement (MSc Nanomedicine)

2024

• Nanomedicine project (15 sp)

2023–2024

• Circadian rhythm genes & endothelial cells – 2 STAMI projects
• Cholesterol crystals in preeclampsia (Medicine)
• Micro/nanoplastics – whole blood inflammation (MSc MolMed)
• Monocyte responses to fucoidan/alginates (MSc Biotech)

2022–2023

• Biopolymer materials for cell transplantation (Fulbright)
• Cytokine responses during weight reduction (MSc Biotech)

2020–2021

• Cholesterol crystals & LPS – thromboinflammation (3 MSc: MolMed/Pharmacy)

2020

• Host–material interaction models (MSc Biotech)

2019

• Biomaterial biocompatibility in whole blood (Biotech project)

2015–2016

• Obesity, leukocyte receptors & inflammation (2 MSc MolMed)

2014–2015

• Atherosclerosis, obesity, cholesterol crystals & complement (2 MSc MolMed)

2012–2013

• Alginate microcapsules & immunology (2 MSc Biotech)

2011–2012

• Alginate microcapsules – complement & cytokines (MSc Biotech)

2009–2010

• Alginate matrix for tissue engineering (MSc Biotech)

2007–2009

• Alginate capsule properties (30 sp project)

2002

• Encapsulated endothelial cells & islets (Graduate thesis)

1999

• Cell viability in alginate capsules (Master)

1995–1999

• Immune activation in fish – mannuronan polymers (Cand. Scient.)

Outreach

Verdens plastproblem - går det på helsa løs?

Er plast helseskadelig? Denne brosjyren gir ett kort sammendrag av viktige momenter og ubesvarte spørsmål knyttet til plast i ett miljø-helse perspektiv.

2025

Academic lecture

Rokstad, Anne Mari A.. (2025) Generalities on MNPs and human health. Micro- and Nanoplastics: Workplace Exposure and Potential Health Hazards , Clarion Hotel, Oslo 07.10.2025 - 08.10.2025

2024

Interview

Lødemel, Oda Flaten; Rokstad, Anne Mari A.; Wagner, Martin; Klingsheim, Karl. (2024) Vil ha konkrete tiltak mot mikroplast: - Må stoppe før det er for seint. nrk.no nrk.no [Internet] 25.09.2024
Interview

Rokstad, Anne Mari A.. (2024) Klar testikkel-beskjed – etterlyser balletak. Nettavisen Nettavisen [Journal] 22.06.2024
Academic lecture

Rokstad, Anne Mari A.. (2024) Inflammatory Responses to Biomaterials. Chicago Diabetes Meeting , Zurich 11.07.2024 - 13.07.2024
Poster

Altermark, Sofie; Vasuthas, Kalaiyarasi; Børset, Magne; Wagner, Martin; Rokstad, Anne Mari A.. (2024) Understanding the human health impacts of nano- and microplastics. Research Day , Trondheim 19.08.2024 - 19.08.2024

2023

Lecture

Brambilla, Alessandro; Coron, Abba Elizabeth; Fonseca, Davi de Miranda; Sharma, Animesh; Slupphaug, Geir; Strand, Berit Løkensgard. (2023) MS-proteomics provides insight into the host responses towards alginate microspheres. A HEALTHY FUTURE , Trondheim 05.10.2023 - 05.10.2023
Poster

Altermark, Sofie; Ragunathan, Kalaiyarasi; Kjølberg, Frida Aune; Wagner, Martin; Rokstad, Anne Mari A.. (2023) Understanding the Human Health Impacts of Micro- and nanoplastics. Microplastics - Workshop for early career reaseachers , Ascona 13.11.2023 - 14.11.2023
Poster

Kjesbu, Joachim Sebastian; Coron, Abba Elizabeth; Rokstad, Anne Mari A.; Strand, Berit Løkensgard. (2023) Alginate Microbead Encapsulation for Cell Therapy: Reduced Fibrotic Response by Intermediate Guluronate Content and Sulfation. ESB2023 , Davos 04.09.2023 - 08.09.2023
Poster

Ragunathan, Kalaiyarasi; Brambilla, Alessandro; Kjesbu, Joachim Sebastian; Fonseca, Davi de Miranda; Sharma, Animesh; Slupphaug, Geir. (2023) The initial host response to alginate-based microbeads in human whole blood depict by functional response and mass spectrometry. ScSB meeting - Bioinspiration in biomaterials , Røros 21.03.2023 - 24.03.2023
Poster

Ragunathan, Kalaiyarasi; Brambilla, Alessandro; Kjesbu, Joachim Sebastian; Fonseca, Davi de Miranda; Sharma, Animesh; Slupphaug, Geir. (2023) Exploring Immunogenicity of Sulphated Alginate Beads: Insights from Whole Blood Model and Protein Adsorption Analysis. A HEALTHY FUTURE , Trondheim 05.10.2023 - 05.10.2023
Poster

Levitan, Maya; Ragunathan, Kalaiyarasi; Kjesbu, Joachim Sebastian; Aachmann, Finn Lillelund; Strand, Berit Løkensgard; Rokstad, Anne Mari A.. (2023) Characterizing the Inflammatory Properties of Novel Fucoidan/Alginate Beads. ScSB meeting - Bioinspiration in biomaterials , Røros 21.03.2023 - 24.03.2023
Academic lecture

Kjesbu, Joachim Sebastian; Coron, Abba Elizabeth; Rokstad, Anne Mari A.; Strand, Berit Løkensgard. (2023) Cell encapsulation in sulfated alginate beads for treatment of type 1 diabetes and acute liver failure. ScSB 2023 , Røros 21.03.2023 - 24.03.2023
Poster

Altermark, Sofie; Ragunathan, Kalaiyarasi; Kjølberg, Frida Aune; Wagner, Martin; Rokstad, Anne Mari A.. (2023) Understanding the human health impacts of nano- and microplastics. A HEALTHY FUTURE , Trondheim 05.10.2023 - 05.10.2023
Poster

Coron, Abba Elizabeth; Kjesbu, Joachim Sebastian; Fonseca, Davi de Miranda; Sharma, Animesh; Slupphaug, Geir; Strand, Berit Løkensgard. (2023) MS-based proteomic profiling of alginate microspheres relevant for cell therapy. ScSB meeting - Bioinspiration in biomaterials , Røros 21.03.2023 - 24.03.2023

2019

Poster

Coron, Abba Elizabeth; Fonseca, Davi de Miranda; Sharma, Animesh; Slupphaug, Geir; Rokstad, Anne Mari A.; Strand, Berit Løkensgard. (2019) Elucidating host responses towards alginate microspheres using proteomics. Scandinavian Society for Biomaterials 2019 Conference , Kirkkonummi 12.06.2019 - 14.06.2019
Poster

Gravastrand, Caroline S.; Steinkjer, Bjørg; Halvorsen, Bente; Landsem, Anne; Skjelland, Mona; Jacobsen, Eva Astrid. (2019) Cholesterol crystals induce thromboinflammation. Conference on molecular mechanisms in Trondheim , Trondheim 03.06.2019 - 06.06.2019
Poster

Treľová, D.; Kleščíková, L.; Raus, V.; Uhelská, L.; Kroneková, Z.; Chovancová, A.. (2019) Multicomponent polyelectrolyte complex-based microcapsules: Correlation between the encapsulation conditions and microcapsule properties. 83rd PRAGUE MEETING ON MACROMOLECULES , Prague, Czech Republic 23.06.2019 - 27.06.2019
Interview

Bazilchuk, Nancy Reney; Gravastrand, Caroline S.; Rokstad, Anne Mari A.. (2019) Cholesterol crystals play an active role in stroke, heart attacks. Norwegian SciTech News Norwegian SciTech News [Internet] 31.10.2019
Interview

Rokstad, Anne Mari A.; Gravastrand, Caroline S.; Bazilchuk, Nancy Reney. (2019) Kolesterolkrystaller kan aktivere blodpropp. Gemini Gemini [Journal] 22.11.2019

2018

Poster

Coron, Abba Elizabeth; Fonseca, Davi de Miranda; Sharma, Animesh; Slupphaug, Geir; Strand, Berit Løkensgard; Rokstad, Anne Mari. (2018) Identification of adsorbing human plasma proteins on alginate gel beads. BRG Capsule workshop 2018 , Trondheim 17.09.2018 - 21.09.2018
Poster

Coron, Abba Elizabeth; Fonseca, Davi de Miranda; Sharma, Animesh; Slupphaug, Geir; Strand, Berit Løkensgard; Rokstad, Anne Mari. (2018) Identification of adsorbing human plasma proteins on alginate gel beads. Nordic Proteomics Conference , Bergen 18.04.2018 - 20.04.2018
Poster

Myklebust, Ivar; Gierman, Lobke; Silva, Gabriela; Bjøru, Hege Tevik; Pavlovic, Ivan; Rokstad, Anne Mari. (2018) Inflammation by danger response in visceral and subcutaneous adipose tissue from obese and lean individuals. Toll 2018 , Porto 06.06.2018 - 09.06.2018
Academic lecture

Rokstad, Anne Mari. (2018) Unmasking the inflammatory properties of a material by the human whole blood model. Teveltunet Conference 2018 , Teveltunet, Trøndelag 03.05.2018 - 04.05.2018
Lecture

Rokstad, Anne Mari. (2018) Celle-innkapslings teknologi ved bruk av alginat – konsept, utfordringer og forskning. Tekna Biotek Trondheim Høstseminar , NTNU, Kjelhuset, auditorium KJ1 23.10.2018 -
Academic lecture

Rokstad, Anne Mari. (2018) Understanding biomaterial inflammation through the whole blood model. 10th Training School on Microencapsulation , NTNU, Trondheim 18.10.2018 - 21.10.2018
Academic lecture

Rokstad, Anne Mari; Gravastrand, Caroline S.; Halvorsen, Bente; Steinkjer, Bjørg; Skjelland, Mona; Jacobsen, Eva Astrid. (2018) Cholesterol crystals induce coagulation that can be prevented by targeting complement. 11th International Conference on Complement Therapeutics , Crete 23.06.2018 - 25.06.2018

2017

Lecture

Rokstad, Anne Mari. (2017) Inflammasjon som årsaksfaktor ved fedmerelaterte sykdommer. BAROBS-studien , Stjørdal, Helse Midt-Norges lokaler 07.09.2017 -
Academic lecture

Lacík, Igor; Rokstad, Anne Mari; Oberholzer, José. (2017) The update on multicomponent PMCG microcapsule and on related activities. JDRF Consortium monthly call , Web seminar, leaded from New York 02.02.2017 - 02.02.2017

2016

Lecture

Lacík, Igor; Rokstad, Anne Mari; Oberholzer, José. (2016) Multicomponent microcapsules for allogeneic islet transplantation in a comprehensive, preclinical non-human primate model. Encapsulation Consortium Spring Meeting , New York 11.04.2016 - 12.04.2016
Lecture

Rokstad, Anne Mari; Coron, Abba Elizabeth; Treľová, Dušana; Razga, Filip; Nemethova, Veronika; Mazancova, Petra. (2016) Multicomponent microcapsules for islets transplantation - tuning their properties towards a low-inflammatory surface by assessments in a human whole blood model. 2nd International Conference on Immune Responses to Biosurfaces: Mechanisms and Therapeutic Interventions , Rhodes 26.09.2016 - 01.10.2016
Poster

Gravastrand, Caroline; Steinkjer, Bjørg; Fure, Hilde; Ryan, Liv; Martins, Catia; Mollnes, Tom Eirik. (2016) Cholesterol crystals induce coagulation activation in a complement-dependent manner. Conference on Molecular Mechanisms of Inflammation , Trondheim 30.05.2016 - 02.06.2016
Poster

Gravastrand, Caroline; Teigen, Ellen; Vorkinn, Ingvild; Steinkjer, Bjørg; Gierman, Lobke; Nymo, Siren. (2016) Effect of rapid weight loss in obese individuals with focus on inflammatory receptor expression in peripheral blood leukocytes. Conference on Molecular Mechanisms of Inflammation , Trondheim 30.05.2016 - 02.06.2016
Academic lecture

Rokstad, Anne Mari. (2016) Effekt av en VLCD diett på markører for inflammasjon, metabolisme og hjerte kar risisko. Fedmeforskningsdagene 2016 i Trondheim , St.Olavs hospital, Trondheim, norge 19.10.2016 - 20.10.2016
Poster

Gravastrand, Caroline; Steinkjer, Bjørg; Fure, Hilde; Niyonzima, Nathalie; Lambris, John D.; Mollnes, Tom Eirik. (2016) Cholesterol crystals induce coagulation activation in a complement-dependent manner. 2nd International Conference on Immune Responses to Biosurfaces: Mechanisms and Therapeutic Interventions , Rhodos 29.09.2016 - 01.10.2016
Lecture

Rokstad, Anne Mari. (2016) Atherosclerosis coagulation and obesity inflammation – is complement the answer?. The annual CEMIR seminar , NTNU/CEMIR 16.11.2016 - 16.11.2016

2015

Poster

Aune, Marie Hjelmseth; Niyonzima, Nathalie; Samstad, Eivind; Bakke, Siril Skaret; Ryan, Liv; Rokstad, Anne Mari. (2015) Crystalline cholesterol is found in atherosclerotic plaques and induces complement mediated inflammation. 15th European Meeting on Complement in Human Disease 27.06.2015 - 30.06.2015
Academic lecture

Rokstad, Anne Mari. (2015) Alginate in cell encapsulation therapy. Gjesteforedrag , Avdeling for biomaterialer, Odontologiske fakultet, UiO 12.05.2015 -
Academic lecture

Nordli, Henriette R.; Rokstad, Anne Mari; Chinga-Carrasco, Gary; Pukstad, Brita. (2015) TEMPO-pretreated wood nanocellulose for wound dressings. BioNanoMed 2015 , Graz 08.04.2015 - 10.04.2015
Lecture

Lacík, Igor; Rokstad, Anne Mari; Oberholzer, José. (2015) Multicomponent microcapsules for allogeneic islet transplantation in a comprehensive, preclinical non-human primate model. , Encapsulation consortium JDRF meeting (presented by Igor Lacik) , New York 01.10.2015 - 01.10.2015
Lecture

Lacík, Igor; Rokstad, Anne Mari; Oberholzer, José. (2015) Multicomponent microcapsules for allogeneic islet transplantation in a comprehensive, preclinical non-human primate model. (presented by Jose Oberholzer). Encapsulation consortium JDRF meeting , New York 12.01.2015 - 12.01.2015
Lecture

Rokstad, Anne Mari. (2015) THE COMPLEMENT C3 DEPOSITION DEPENDS ON THE ALGINATE MICROSPHERES COMPOSITION AND DETERMINDS THE CYTOKINE PROFILE. Functional polymers at bio-material interfaces, 79th Prague meeting on macromolecules , Prague 28.06.2015 - 02.07.2015

2014

Lecture

Rokstad, Anne Mari. (2014) Inflammatory Reactions to Microcapsules in a Human Whole Blood Model. Instituttseminar Inst bioteknologi (NTNU) , Institutt bioteknologi (NTNU) 29.10.2014 -
Lecture

Rokstad, Anne Mari. (2014) Inflammatory Reactions to Microcapsules in a Human Whole Blood Model. Tissue Engineering of the Bioartificial Pancreas to Functionally Cure Diabetes , St.Olavs hospital, Kunnskapsenteret (NTNU) 03.09.2014 -
Academic lecture

Nordli, Henriette R.; Pukstad, Brita; Rokstad, Anne Mari; Chinga-Carrasco, Gary. (2014) Wood nanocellulose – assessment of toxicity and effects on activation of the complement and coagulation pathways using a whole blood model. Cellulose nanotechnology research , Trondheim 28.10.2014 - 29.10.2014
Academic lecture

Nordli, Henriette R.; Rokstad, Anne Mari; Chinga-Carrasco, Gary; Pukstad, Brita. (2014) Immunogenic properties of TEMPO-treated wood nanocellulose. BioNanoMed 2014 , Krems 26.03.2014 - 28.03.2014
Lecture

Rokstad, Anne Mari; Ørning, Mathias Pontus; Hamad, Shamal; Hoem, Kine Samseth; Steinkjer, Bjørg; Fure, Hilde. (2014) Inflammatory and hemostatic activation induced by alginate microcapsules reveals novel mechanisms underlying their biocompatibility. Immune responces to biosurfaces: Mechanisms and therapeutic interventions , Crete 27.09.2014 - 02.10.2014
Lecture

Rokstad, Anne Mari; Hamad, Shamal; Steinkjer, Bjørg; Fure, Hilde; Niyonzima, Nathalie; Ørning, Mathias Pontus. (2014) Initial inflammatory and haemostatic mechanisms induced by endogenous and bioartificial surfaces in a whole blood model. NBS contact Meeting 2014 , Røros 23.01.2014 - 26.01.2014
Academic lecture

Qi, Meirigeng; Hloušková, Gabriela; Wang, Yong; Bochenek, Matthew A.; Marchese, Enza; McGarrigle, James J.. (2014) Polyelectrolyte complex-based microcapsules for transplantation of encapsulated allogeneic islets in baboons. Macro 2014 , Chiang Mai 06.07.2014 - 11.07.2014

2012

Academic lecture

Rokstad, Anne Mari. (2012) Inflammation complement and coagulation. Whole blood and Biomaterials. TOLL-dagen 2012 , Trondheim 16.11.2012 -
Poster

Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Lambris, John D.. (2012) Poly-cation containing alginate microcapsules induce cytokines by a complement-dependent mechanism. XXIV. International Complement Workshop , Chania, Crete, Greece, october 10-15, 2012 10.10.2012 - 15.10.2012
Academic lecture

Rokstad, Anne Mari. (2012) Update on whole blood. 8th Chicago Diabetes Project Meeting, October 2012 , University of Illinois (UIC) at Chicago 08.10.2012 - 10.10.2012
Lecture

Rokstad, Anne Mari. (2012) Mechanisms behind inflammatory reactions to biomaterials. Onsdagsmøte ved IKM, NTNU , Laboratoriesenteret (LS41), DMF, NTNU 28.03.2012 -

2011

Academic lecture

Mørch, Yrr Asbjørg; Strand, Berit Løkensgard; Rokstad, Anne Mari; Skjåk-Bræk, Gudmund. (2011) Alginate Microcapsules for the Treatment of Type 1 Diabetes. National Congress of the Norwegian Chemical Society, Invited speaker , Lillestrøm 28.09.2011 - 29.09.2011
Academic lecture

Rokstad, Anne Mari; Ryan, Liv; Steinkjer, Bjørg; Brekke, Ole Lars; Qi, Meirigeng; Oberholzer, José. (2011) Inflammatory responses of alginate microspehers evaluated by a human and baboon whole blood model. 13th world Congress of IPITA International Pancreas and Islets Transplant Association , Prague 01.06.2011 - 04.06.2011

2008

Academic lecture

Rokstad, Anne Mari. (2008) Alginate capsules and biocompatibility issues. Tirsdagsmøte for DMF, NTNU og St. Olavs Hospital , Trondheim 15.04.2008 -
Poster

Rokstad, Anne Mari; Steinkjer, Bjørg; Lien, Egil; Espevik, Terje. (2008) TOLL like receptor 4 is involved in inflammatory reactions (overgrowth) against alginate capsules. TOLL2008 Meeting; Recent advances in Pattern recognition , Lisboa 24.09.2008 - 27.09.2008
Academic lecture

Rokstad, Anne Mari. (2008) Biocompatibility, inflammation and cell encapsulation therapy. Tirsdagsmøte , Trondheim 15.04.2008 - 15.04.2008

2007

Interview

Lyseggen, Kristin; Rokstad, Anne Mari Aukan. (2007) "Håp for kreft". Bioteknologi, 2.utgave Bioteknologi, 2.utgave [Internet] 01.09.2007
Academic lecture

Rokstad, Anne Mari Aukan. (2007) Kan TOLL-reseptorer og adaptormolekyler være involvert i overvekst på alginatkapsler?. TOLL-gruppe møte , DMF, NTNU, Trondheim 26.03.2007 - 26.03.2007

2006

Lecture

Rokstad, Anne Mari Aukan. (2006) Stem cells in therapy - hype and reality. NBS høstmøte 2006 , Røros 18.09.2006 - 19.09.2006
Academic lecture

Rokstad, Anne Mari Aukan; Donati, Ivan; Borgogna, Massilimo; Oberholzer, José; Strand, Berit Løkensgard; Espevik, Terje. (2006) Cell-compatible covalent alginate beads obtained from a chemoenzymatically engineered alginate. XIV International workshop on bioencapsulation & COST 865 meeting , Lausanne 05.10.2006 - 07.10.2006
Academic lecture

Rokstad, Anne Mari Aukan. (2006) Alginate capsules for treatment of diabetes and brain tumor. TOLL-seminar , Trondheim 13.09.2006 - 13.09.2006
Academic lecture

Rokstad, Anne Mari Aukan. (2006) Covalent cross-linked alginate beads compatible for encapsulated cells. NOBIPOL seminar , Tevletunet 04.05.2006 - 05.05.2006
Academic lecture

Rokstad, Anne Mari Aukan. (2006) When human cells or organs fail – could the pig be of any help?. Prøveforelesning, disputas , Trondheim 23.03.2006 - 23.03.2006
Academic lecture

Rokstad, Anne Mari Aukan. (2006) Stem cells in therapy – hype and reality. Prøveforelesning, disputas , Trondheim 23.03.2006 - 23.03.2006
Academic lecture

Mørch, Yrr Asbjørg; Strand, Berit Løkensgard; Donati, Ivan; Rokstad, Anne Mari Aukan; Skjåk-Bræk, Gudmund. (2006) Improvement of Alginate Microbeads using enzymatic modification. XIVth International Workshop on Bioencapsulation , Lausanne 05.10.2006 - 07.10.2006

2005

Poster

Rokstad, Anne Mari Aukan; Strand, Berit Løkensgard; Rian, Kristin; Steinkjer, Bjørg; Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund. (2005) Making alginate bioreactors for treatment of brain tumours: strategies for optimalisation of the system. The Norwegian Biochemical Society 41st Contact Meeting , Tromsø 13.01.2005 - 16.01.2005

2002

Academic lecture

Skjermo, Jorunn; Rokstad, Anne Mari Aukan; Salvesen, Ingrid; Skjåk-Bræk, Gudmund; Vadstein, Olav. (2002) Immunostimulation in marine larval rearing. ICES 2002 Annual Science Conference , Copenhagen 05.10.2002 -
Academic lecture

Rokstad, Anne Mari Aukan; Strand, Berit Løkensgard; Rian, Kristin; Steinkjer, Bjørg; Ryan, Liv; Kulseng, Bård Eirik. (2002) Evaluation of different alginate microcapsules as bioreactors for 293-EBNA cells delivering the anti-angiogenic factor endostatin. 38.Biokjemiske kontaktmøte Functional genomics-the mosaics of life , Røros 20.01.2002 -

2001

Lecture

Rokstad, Anne Mari Aukan. (2001) Alginate capsules for transplantation of cells. , Medisinsk Teknisk Senter 16.10.2001 -
Poster

Skjermo, Jorunn; Rokstad, Anne Mari Aukan; Salvesen, Ingrid; Skjåk-Bræk, Gudmund. (2001) Immunostimulation as counteraction to bacterial problems in first feeding of marine larve. European Aquaculture Society Meeting , Gent, Belgium 06.09.2001 -
Poster

King, A.; Strand, Berit L.; Rokstad, Anne Mari Aukan; Kulseng, Bård Eirik; Andersson, A.; Skjåk-Bræk, Gudmund. (2001) Epimerised alginate: effect on biocompatibility of microcapsules. Scandinavian Socisty for the Study of Diabetes , Uppsala 25.05.2001 -
Academic lecture

Strand, Berit Løkensgard; Mørch, Yrr Asbjørg; Rokstad, Anne Mari Aukan; Kulseng, Bård Eirik; Espevik, Terje; Skjåk-Bræk, Gudmund. (2001) Improved capsule properties by the use of epimerised alginate. The Ninth International Workshop in Bioencapsulation , Warsawa 11.05.2001 - 13.05.2001
Academic lecture

King, Aileen; Strand, Berit Løkensgard; Rokstad, Anne Mari Aukan; Kulseng, Bård Eirik; Andersson, Arne; Sandler, Stellan. (2001) Improved biocompatibility of alginate-Poly-L-lysine-alginate microcapsules prepared with epimerized alginates. The 8th World Congress of the International Pancreas & Islet Transplant Association , Innsbruck 12.06.2001 - 15.06.2001

2000

Poster

Rokstad, Anne Mari Aukan; Kulseng, Bård Eirik; Strand, B.; Skjåk-Bræk, Gudmund; Espevik, Terje. (2000) Transplantation of Alginate Microcapsules with proliferating cells in mice: Capsular overgrowth and survival of encapsulated cells in allo-and xeno graft modells. Bioartificial organs III. Tissue Sourcing, Immunosolation and Clinical Trials. , Davos, Switzerland, 7-12 okt. 2000
Poster

Strand, Berit Løkensgard; Kulseng, Bård Eirik; Rokstad, Anne Mari Aukan; Skjåk-Bræk, Gudmund; Espevik, Terje. (2000) Identification of cells in the fibrotic reaction against transplanted encapsulated cells. Islets in Eilat: A combined islet basic science and transplantation meeting , Eilat 21.09.2000 - 24.09.2000

1999

Lecture

Rokstad, Anne Mari Aukan; Skjåk-Bræk, Gudmund; Skjermo, Jorun. (1999) In vitro og in vivo effekter av alginater på piggvarleukocytter. Fiske- og dyrehelsemøtet 1999 , Tromsø 18.01.1999 - 20.01.1999
Lecture

Rokstad, Anne Mari Aukan; Espevik, Terje; Skjåk-Bræk, Gudmund; Vadstein, Olav; Skjermo, Jorun. (1999) Alginates as adjuvant in fish vaccine against Aeromonas salmonicida. 35. Biokjemiske Kontaktmøte, NBS , Tromsø, 21-24. januar 1999

Språkvelger

Anne Mari A. Rokstad