Astrid Lægreid

About

Research interest

Systems biology and its translations to new biomedical approaches.

The Knowledge Commons as foundation for systems biology.

Wide interdisciplinarity spanning humanities, science and technology as a quality and relevance enhancing research mode.

Current research projects

Leader: "Rational development of anti-cancer drug combinations"

Partner: "Crossover Research" and "COLOSYS"

Background

Lægreid studied biochemistry, mathematics and musicology before doing a master (1982) and PhD (1985) in biochemistry at the University of Oslo. During her post doctor, Lægreid entered the field of molecular biology which she applied in cancer research. Lægreid played a central role in the establishment of the national functional genomics research programme where she also headed the NTNU platform-node of the National Consortium of Microarray Technology. Lægreid has pursued epistemic and socio-ethical questions as a central part of her efforts to transform her cancer research strategies from traditional molecular cell biology into a systems biology approach.

Current position: Professor in functional genomics, Department of Cancer Research and Molecular Medicine, NTNU; Past university leadership positions: Vice Dean, Research, of the Medical faculty, NTNU, 1996-1999; Prorector, Research and Innovation of NTNU, 2005-2009

Publications

2023

Heck, Kathleen; Lindholm, Håvard Takle; Niederdorfer, Barbara; Tsirvouli, Eirini; Kuiper, Martin; Flobak, Åsmund; Lægreid, Astrid Renner; Thommesen, Liv. (2023) Characterisation of Colorectal Cancer Cell Lines through Proteomic Profiling of Their Extracellular Vesicles. Proteomes. volum 11 (1).
Academic article

2022

Kuiper, Martin; Bonello, Joseph; Fernández-Breis, Jesualdo Tomás; Bucher, Philipp; Futschik, Matthias E; Gaudet, Pascale; Kulakovskiy, Ivan V.; Licata, Luana; Logie, Colin; Lovering, Ruth C.; Makeev, Vsevolod J; Orchard, Sandra; Panni, Simona; Perfetto, Livia; Sant, David; Schulz, Stefan M.; Vercruysse, Steven; Zerbino, Daniel; Lægreid, Astrid. (2022) The gene regulation knowledge commons: the action area of GREEKC. Biochimica et Biophysica Acta. Gene Regulatory Mechanisms. volum 1865 (1).
Academic article
Vazquez Garcia, Miguel; Krallinger, Martin; Leitner, Florian; Kuiper, Martin; Valencia, Alfonso; Lægreid, Astrid. (2022) ExTRI: Extraction of transcription regulation interactions from literature. Biochimica et Biophysica Acta. Gene Regulatory Mechanisms. volum 1865 (1).
Academic article

2021

Carbon, Seth J.; Douglass, Eric; Good, Benjamin M; Unni, Deepak R; Harris, Nomi L.; Mungall, Christopher J.; Basu, Siddartha; Chisholm, Rex L.; Dodson, Robert J.; Hartline, Eric; Fey, Petra; Thomas, Paul D.; Albou, Laurent-Philippe; Ebert, Dustin; Kesling, Michael J; Mi, Huaiyu; Muruganujan, Anushya; Huang, Xiaosong; Mushayahama, Tremayne. (2021) The Gene Ontology resource: enriching a GOld mine. Nucleic Acids Research (NAR).
Academic article
Gaudet, Pascale; Logie, Colin; Lovering, Ruth C.; Kuiper, Martin; Lægreid, Astrid; Thomas, Paul D.. (2021) Gene Ontology representation for transcription factor functions. Biochimica et Biophysica Acta. Gene Regulatory Mechanisms. volum 1864 (11-12).
Academic article
Juanes Cortés, Belén; Vera-Ramos, José Antonio; Lovering, Ruth C.; Gaudet, Pascale; Lægreid, Astrid; Logie, Colin; Schulz, Stefan; Roldán-García, María del Mar; Kuiper, Martin; Fernández-Breis, Jesualdo Tomás. (2021) Formalization of gene regulation knowledge using ontologies and gene ontology causal activity models. Biochimica et Biophysica Acta. Gene Regulatory Mechanisms. volum 1864 (11-12).
Academic article
Lovering, Ruth C.; Gaudet, Pascale; Acencio, Marcio Luis; Ignatchenko, Alex; Jolma, Arttu; Fornes, Oriol; Kuiper, Martin; Kulakovskiy, Ivan V.; Lægreid, Astrid; Martin, Maria J.; Logie, Colin. (2021) A GO catalogue of human DNA-binding transcription factors. Biochimica et Biophysica Acta. Gene Regulatory Mechanisms. volum 1864 (11-12).
Academic article

2020

Folkesson, Evelina; Niederdorfer, Barbara; Nakstad, Vu To; Thommesen, Liv; Klinkenberg, Geir; Lægreid, Astrid; Flobak, Åsmund. (2020) Author Correction: High-throughput screening reveals higher synergistic effect of MEK inhibitor combinations in colon cancer spheroids (Scientific Reports, (2020), 10, 1, (11574), 10.1038/s41598-020-68441-0). Scientific Reports. volum 10 (1).
Errata
Folkesson, Evelina; Niederdorfer, Barbara; To, Vu; Thommesen, Liv; Klinkenberg, Geir; Lægreid, Astrid; Flobak, Åsmund. (2020) High-throughput screening reveals higher synergistic effect of MEK inhibitor combinations in colon cancer spheroids. Scientific Reports. volum 10.
Academic article
Niederdorfer, Barbara; Touré, Vasundra; Vazques, Miguel; Thommesen, Liv; Kuiper, Martin Tremen R.; Lægreid, Astrid; Flobak, Åsmund. (2020) Strategies to Enhance Logic Modeling-Based Cell Line-Specific Drug Synergy Prediction. Frontiers in Physiology. volum 11.
Academic article
Nydal, Rune; Bennett, Gaymon; Kuiper, Martin; Lægreid, Astrid. (2020) Silencing trust: confidence and familiarity in re-engineering knowledge infrastructures. Medicine, Health care and Philosophy.
Academic article
Touré, Vasundra; Vercruysse, Steven; Acencio, Marcio Luis; Lovering, Ruth C.; Orchard, Sandra; Bradley, Glyn; Casals-Casas, Cristina; Chaouiya, Claudine; del-Toro, Noemi; Flobak, Åsmund; Gaudet, Pascale; Hermjakob, Henning; Hoyt, Charles Tapley; Licata, Luana; Lægreid, Astrid; Mungall, Christopher; Niknejad, Anne; Panni, Simona; Perfetto, Livia. (2020) The Minimum Information about a Molecular Interaction Causal Statement (MI2CAST). Bioinformatics.
Academic article

2019

Carbon, Seth J.; Douglass, E; Dunn, N; Good, B; Harris, NL; Lewis, SE; Mungall, CJ; Basu, S; Chisholm, RL; Dodson, RJ; Hartline, E; Fey, P; Thomas, PD; Albou, LP; Ebert, D; Kesling, MJ; Mi, H; Muruganujan, A; Huang, X. (2019) The Gene Ontology Resource: 20 years and still GOing strong. Nucleic Acids Research (NAR). volum 47 (gky1055).
Academic article
Efstathiou, Sophia; Nydal, Rune; Lægreid, Astrid; Kuiper, Martin. (2019) Scientific knowledge in the age of computation: Explicated, computable and manageable?. Theoria. An international Journal of Theory, History and Foundations of Science. volum 34 (2).
Academic article
Flobak, Åsmund; Niederdorfer, Barbara; To, Vu; Thommesen, Liv; Klinkenberg, Geir; Lægreid, Astrid. (2019) A high-throughput drug combination screen of targeted small molecule inhibitors in cancer cell lines. Scientific Data. volum 6.
Academic article
Menden, Michael Patrick; Wang, Dennis; Mason, Mike J.; Szalai, Bence; Bulusu, Krishna C.; Guan, Yuanfang; Flobak, Åsmund; Kuiper, Martin; Lægreid, Astrid; Thommesen, Liv. (2019) Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen. Nature Communications. volum 10 (2674).
Academic article
Perfetto, Livia; Acencio, Marcio Luis; Bradley, Glyn; Cesareni, Gianni; del Toro, Noemi; Fazekas, David; Hermjakob, Henning; Korcsmaros, Tamas; Kuiper, Martin; Lægreid, Astrid; Lo Surdo, Prisca; Lovering, Ruth C.; Orchard, Sandra; Porras, Pablo; Thomas, Paul; Touré, Vasundra; Zobolas, John; Licata, Luana. (2019) CausalTAB: the PSI-MITAB 2.8 updated format for signalling data representation and dissemination. Bioinformatics. volum 35 (19).
Academic article
Vera-Ramos, Jose Antonio; Juanes-Cortes, Belen; Fernández-Breis, Jesualdo Tomás; Gaudet, Pascale; Kuiper, Martin; Lægreid, Astrid; Logie, Colin; Roldan-Garcia, Maria del Mar; Schulz, Stefan. (2019) An example of multimodal biological knowledge representation. CEUR Workshop Proceedings. volum 2518.
Academic article

2017

Flobak, Åsmund; Garcia, Miguel Vazquez; Lægreid, Astrid; Valencia, Alfonso. (2017) CImbinator: a web-based tool for drug synergy analysis in small- and large-scale datasets. Bioinformatics. volum 33 (15).
Academic article

2016

Tripathi, Sushil; Vercruysse, Steven; Chawla, Konika; Christie, Karen R.; Blake, Judith A; Huntley, Rachael P.; Orchard, Sandra; Hermjakob, Henning; Thommesen, Liv; Lægreid, Astrid; Kuiper, Martin. (2016) Gene regulation knowledge commons: community action takes care of DNA binding transcription factors. Database: The Journal of Biological Databases and Curation.
Academic article

2015

Flobak, Åsmund; Baudot, Anaïs; Remy, Elisabeth; Thommesen, Liv; Thieffry, Denis; Kuiper, Martin; Lægreid, Astrid. (2015) Discovery of Drug Synergies in Gastric Cancer Cells Predicted by Logical Modeling. PLoS Computational Biology. volum 11 (8).
Academic article
Lægreid, Astrid; Kuiper, Martin. (2015) Health and the information commons.
Website (informational material)
Tripathi, Sushil; Flobak, Åsmund; Chawla, Konika; Baudot, Anaïs; Bruland, Torunn; Thommesen, Liv; Kuiper, Martin Tremen R.; Lægreid, Astrid. (2015) The gastrin and cholecystokinin receptors mediated signaling network: a scaffold for data analysis and new hypotheses on regulatory mechanisms. BMC Systems Biology. volum 9 (40).
Academic article

2014

Lægreid, Astrid; Kuiper, Martin. (2014) Å ta seg av kunnskap.
Website (informational material)
Orchard, Sandra; Ammari, M; Aranda, B; Breuza, L; Briganti, L; Broackes-Carter, F; Campbell, NH; Chavali, G; Chen, C; Del-Toro, N; Duesbury, M; Dumousseau, M; Galeota, E; Hinz, U; Iannuccelli, M; Jagannathan, S; Jimenez, R.; Khadake, J; Lægreid, Astrid. (2014) The MIntAct project - IntAct as a common curation platform for 11 molecular interaction databases. Nucleic Acids Research (NAR). volum 42 (1).
Academic article
Selvik, Linn-Karina M.; Rao, Shalini; Steigedal, Tonje; Haltbakk, Ildri; Misund, Kristine; Bruland, Torunn; Prestvik, Wenche S; Lægreid, Astrid; Thommesen, Liv. (2014) Salt-inducible kinase 1 (SIK1) is induced by gastrin and inhibits migration of gastric adenocarcinoma cells. PLOS ONE. volum 9 (11).
Academic article
Venkatesan, Aravind; Tripathi, Sushil; Sanz de Galdeano, Alejandro; Blondé, Ward; Lægreid, Astrid; Mironov, Vladimir; Kuiper, Martin. (2014) Finding gene regulatory network candidates using the gene expression knowledge base. BMC Bioinformatics. volum 15 (1).
Academic article

2013

Chawla, Konika; Tripathi, Sushil; Thommesen, Liv; Lægreid, Astrid; Kuiper, Martin. (2013) TFcheckpoint: a curated compendium of specific DNA-binding RNA polymerase II transcription factors. Bioinformatics. volum 29 (19).
Academic article
Feuerherm, Astrid Jullumstrø; Jørgensen, Katarina Mariann; Sommerfelt, Randi Magnus; Eidem, Live Egeland; Lægreid, Astrid; Johansen, Berit. (2013) Platelet-activating factor induces proliferation in differentiated keratinocytes. Molecular and Cellular Biochemistry. volum 384 (1-2).
Academic article
Misund, Kristine; Selvik, Linn-Karina M.; Rao, Shalini; Nørsett, Kristin Gabestad; Bakke, Ingunn; Sandvik, Arne; Lægreid, Astrid; Bruland, Torunn; Prestvik, Wenche S; Thommesen, Liv. (2013) NR4A2 is regulated by Gastrin and involved in gastrin-induced migration and invasion of gastric adenocarcinoma cells. PLOS ONE. volum 8 (9).
Academic article
Selvik, Linn-Karina M.; Fjeldbo, Christina Sæten; Flatberg, Arnar; Steigedal, Tonje; Misund, Kristine; Anderssen, Endre; Doseth, Berit; Langaas, Mette; Tripathi, Sushil; Beisvag, Vidar; Lægreid, Astrid; Thommesen, Liv; Bruland, Torunn. (2013) The duration of gastrin treatment affects global gene expression and molecular responses involved in ER stress and anti-apoptosis. BMC Genomics. volum 14.
Academic article
Steigedal, Tonje; Prestvik, Wenche S; Selvik, Linn-Karina M.; Fjeldbo, Christina Sæten; Bruland, Torunn; Lægreid, Astrid; Thommesen, Liv. (2013) Gastrin-induced proliferation involves MEK partner 1 (MP1). In vitro Cellular & Developmental Biology-Animal. volum 49 (3).
Academic article
Tripathi, Sushil; Christie, KR; Balakrishnan, Ravin; Huntley, R; Hill, DP; Thommesen, Liv; Blake, JA; Kuiper, Martin; Lægreid, Astrid. (2013) Gene Ontology annotation of sequence-specific DNA binding transcription factors: setting the stage for a large-scale curation effort. Database: The Journal of Biological Databases and Curation.
Academic article

2012

Fjeldbo, Christina Sæten; Bakke, Ingunn; Erlandsen, Sten Even; Holmseth, Jannicke; Lægreid, Astrid; Sandvik, Arne Kristian; Thommesen, Liv; Bruland, Torunn. (2012) Gastrin upregulates the pro-survival factor secretory clusterin (sCLU) in adenocarcinoma cells and in oxyntic mucosa of hypergastrinemic rats. American Journal of Physiology - Gastrointestinal and Liver Physiology. volum 302 (1).
Academic article
Nydal, Rune; Efstathiou, Sophia; Lægreid, Astrid. (2012) Crossover Research: Exploring a Collaborative Mode of Integration. Little by Little. Expansions of Nanoscience and Emerging Technologies.
Academic chapter/article/Conference paper

2010

Fjeldbo, Christina Sæten; Misund, Kristine; Günther, Clara-Cecilie; Langaas, Mette; Steigedal, Tonje; Thommesen, Liv; Lægreid, Astrid; Bruland, Torunn. (2010) Functional studies on RNA-transfected cell microarrays. Methods in molecular biology. volum 629.
Academic article
Jørgensen, Katarina; Felberg, Hanne Solvang; Berge, Rolf K.; Lægreid, Astrid; Johansen, Berit. (2010) Platelet activating factor stimulates arachidonic acid release in differentiated keratinocytes via arachidonyl non-selective phospholipase A(2). Archives of Dermatological Research. volum 302 (3).
Academic article

2009

Hvidsten, Torgeir; Lægreid, Astrid; Kryshtafovych, Andriy; Andersson, Gunnar; Fidelis, Krzysztof; Komorowski, J. (2009) A comprehensive analysis of the structure-function relationship in proteins based on local structure similarity. PLOS ONE. volum 4 (7).
Academic article
Lægreid, Astrid; Feilberg, Julie. (2009) Using the classification system for institutional profiling : the Norwegian University of Science and technology. Mapping the Higher Education Landscape :.
Academic chapter/article/Conference paper

2008

Fjeldbo, Christina Sæten; Misund, Kristine; Günther, Clara-Cecilie; Langaas, Mette; Steigedal, Tonje Strømmen; Thommesen, Liv; Lægreid, Astrid; Bruland, Torunn. (2008) Functional studies on transfected cell microarray analysed by linear regression modelling. Nucleic Acids Research (NAR). volum 36 (15).
Academic article
Fjeldbo, Christina Sæten; Misund, Kristine; Gunther, Clara-Cecilie; Langaas, Mette; Steigedal, Tonje; Thommesen, Liv; Lægreid, Astrid; Bruland, Torunn. (2008) Functional studies on transfected cell microarray analysed by linear regression modelling. Nucleic Acids Research (NAR). volum 36 (15).
Academic article
Hofsli, Eva; Wheeler, Tom Even; Langaas, Mette; Lægreid, Astrid; Thommesen, Liv. (2008) Identification of novel neuroendocrine-specific tumour genes. British Journal of Cancer. volum 99 (8).
Academic article
Hofsli, Eva; Wheeler, Tommy L.; Langaas, Mette; Lægreid, Astrid; Thommesen, Liv. (2008) Identification of novel neuroendocrine-specific tumour genes. British Journal of Cancer. volum 99 (8).
Academic article
Nørsett, Kristin; Lægreid, Astrid; Kusnierczyk, Waclaw; Langaas, Mette; Ylving, S; Fossmark, Reidar; Myhre, Simen; Falkmer, Sture Emil; Waldum, Helge; Sandvik, Arne Kristian. (2008) Changes in gene expression of gastric mucosa during therapeutic acid inhibition. European Journal of Gastroenterology and Hepathology. volum 20.
Academic article

2007

Bruland, Torunn; Anderssen, Endre; Eitrem, Berit Doseth; Bergum, Hallgeir; Beisvåg, Vidar; Lægreid, Astrid. (2007) Optimization of cDNA microarrays procedures using criteria that do not rely on external standards. BMC Genomics. volum 8 (1).
Academic article
Misund, Kristine; Steigedal, Tonje Strømmen; Lægreid, Astrid; Thommesen, Liv. (2007) Inducible cAMP early repressor splice variants ICER I and IIgamma both repress transcription of c-fos and chromogranin A. Journal of Cellular Biochemistry. volum 101 (6).
Academic article
Misund, Kristine; Steigedal, Tonje; Lægreid, Astrid; Thommesen, Liv. (2007) Inducible cAMP early repressor splice variants ICER I and II gamma both repress transcription of c-fos and chromogranin A. Journal of Cellular Biochemistry. volum 101.
Academic article
Steigedal, Tonje Strømmen; Bruland, Torunn; Misund, Kristine; Thommesen, Liv; Lægreid, Astrid. (2007) Inducible cAMP early repressor suppresses gastrin-mediated activation of cyclin D1 and c-fos gene expression. American Journal of Physiology - Gastrointestinal and Liver Physiology. volum 292 (4).
Academic article
Steigedal, Tonje; Bruland, Torunn; Misund, Kristine; Thommesen, Liv; Lægreid, Astrid. (2007) Inducible cAMP early repressor suppresses gastrin-mediated activation of cyclin D1 and c-fos gene expression. American Journal of Physiology - Gastrointestinal and Liver Physiology. volum 292 (4).
Academic article
Sætre, Rune; Ranang, Martin Thorsen; Steigedal, Tonje Strømmen; Stunes, Kamilla; Misund, Kristine; Thommesen, Liv; Lægreid, Astrid. (2007) Webprot : online mining and annotation of biomedical literature using Google. Advanced computational methods for biocomputing and bioimaging.
Academic chapter/article/Conference paper

2006

Beisvag, Vidar; Lehre, PK; Midelfart, H; Aas, Halfdan; Geiran, Odd; Sandvik, Arne K; Lægreid, A.; Komorowski, J.; Ellingsen, Øyvind. (2006) Aetiology-specific patterns in end-stage heart failure patients identified by functional annotation and classification of microarray data. European Journal of Heart Failure. volum 8 (4).
Academic article
Beisvåg, Vidar; Jünge, Frode KR; Bergum, Hallgeir; Jølsum, Lars; Lydersen, Stian; Gunther, Clara-Cecilie; Ramampiaro, Heri; Langaas, Mette; Sandvik, Arne Kristian; Lægreid, Astrid. (2006) GeneTools - application for functional annotation and statistical hypothesis testing. BMC Bioinformatics. volum 7 (470).
Book review
Beisvåg, Vidar; Lehre, Per Kristian; Midelfart, Herman; Aass, H; Geiran, O; Sandvik, Arne Kristian; Lægreid, Astrid; Komorowski, Jan; Ellingsen, Øyvind. (2006) Aetiology-specific patterns in end-stage heart failure patients identified by functional annotation and classification of microarray data. European Journal of Heart Failure. volum 8.
Academic article
Myhre, S; Tveit, Henrik; Mollestad, Torulf; Lægreid, Astrid. (2006) Additional Gene Ontology structure for improved biological reasoning. Bioinformatics. volum 22 (16).
Academic article
Sandvik, Arne Kristian; Alsberg, Bjørn Kåre; Nørsett, Kristin; Yadetie, Fekadu; Waldum, Helge; Lægreid, Astrid. (2006) Gene expression analysis and clinical diagnosis. Clinica Chimica Acta. volum 363.
Academic literature review

2005

Hofsli, Eva; Thommesen, Liv; Yadetie, Fekadu; Langaas, Mette; Sandvik, Arne K.; Lægreid, Astrid. (2005) Identification of novel growth factor-responsive genes in neuroendocrine gastrointestinal tumour cells. British Journal of Cancer. volum 92 (8).
Academic article
Kusnierczyk, Waclaw; Aamodt, Agnar; Lægreid, Astrid. (2005) Knowledge-Intensive Case-Based Support for Automated Explanation of Biological Phenomena. 6th International Conference on Case-Based Reasoning (ICCBR 2005), 23-26 August 2005. Workshop Proceedings.
Academic chapter/article/Conference paper
Sætre, Rune; Tveit, Amund; Ranang, Martin Thorsen; Strømmen, Tonje; Thommesen, Liv; Stunes, Astrid Kamilla; Lægreid, Astrid. (2005) gProt: Annotating Protein Interactions Using Google and Gene Ontology. Lecture Notes in Computer Science (LNCS). volum 3683.
Academic article
Thommesen, Liv; Lægreid, Astrid. (2005) Distinct differences between TNF receptor 1-and TNF receptor 2-mediated activation of NF kappa B. Journal of Biochemistry and Molecular Biology. volum 38.
Academic article
Tveit, Amund; Sætre, Rune; Strømmen, Tonje; Lægreid, Astrid. (2005) ProtChew: Automatic Extraction of Protein Names from Biomedical Literature. Proceedings - International Conference on Data Engineering.
Academic article
Hofsli, Eva; Thommesen, Liv; Yadetie, Fekadu; Langaas, Mette; Kusnierczyk, Waclaw; Falkmer, Ursula; Sandvik, Arne Kristian; Lægreid, Astrid. (2005) Identification of novel growth factor-responsive genes in neuroendocrine gastrointestinal tumour cells. British Journal of Cancer. volum 92.
Academic article
Nørsett, Kristin; Lægreid, Astrid; Langaas, Mette; Wørlund, Sara Maria; Fossmark, Reidar; Waldum, Helge; Sandvik, Arne Kristian. (2005) Molecular characterization of rat gastric mucosal response to potent acid inhibition. Physiological Genomics. volum 22.
Academic article
Sandvik, Arne Kristian; Alsberg, Bjørn Kåre; Nørsett, Kristin; Yadetie, Fekadu; Waldum, Helge; Lægreid, Astrid. (2005) Gene expression analysis and clinical diagnosis. Clinica Chimica Acta.
Academic literature review
Sætre, Rune; Tveit, Amund; Ranang, Martin Thorsen; Steigedal, Tonje Strømmen; Thommesen, Liv; Stunes, Kamilla; Lægreid, Astrid. (2005) gProt: Annotating protein interactions using Google and Gene Ontology. Lecture Notes in Computer Science.
Academic chapter/article/Conference paper
Sætre, Rune; Tveit, Amund; Strømmen, Tonje; Lægreid, Astrid. (2005) Semantic annotation of biomedical literature using Google. Lecture Notes in Computer Science (LNCS). volum 3482 (3).
Academic article
Thommesen, Liv; Lægreid, Astrid. (2005) Distinct differences between TNF receptor 1-and TNF receptor 2-mediated activation of NF kappa B. Journal of Biochemistry and Molecular Biology. volum 38 (3).
Academic article

2004

Drabløs, Finn; Hammer, Mikael; Lægreid, Astrid; Hauglid, Jon Olav; Alsberg, Bjørn Kåre. (2004) Bioinformatics. Infosam2020, Information Society of 2020.
Academic chapter/article/Conference paper
Flikka, K; Lægreid, Astrid. (2004) XHM: A system for detection of potential cross hybridizations in DNA microarrays. BMC Bioinformatics.
Academic article
Flikka, Kristian; Yadetie, Fekadu; Lægreid, Astrid; Jonassen, Inge. (2004) XHM: A system for detection of potential cross hybridizations in DNA microarrays. BMC Bioinformatics. volum 5.
Academic article
Flikka, Kristian; Yadetie, Fekadu; Lægreid, Astrid; Jonassen, Inge. (2004) XHM: a system for detection of potential cross hybridizations in DNA microarrays. BMC Bioinformatics. volum 5 (117).
Academic article
Flikka, Kristian; Yadetie, Fekadu; Lægreid, Astrid; Jonassen, Inge. (2004) XHM: a system for detection of potential cross hybridizations in DNA microarrays. BMC Bioinformatics. volum 5 (117).
Academic article
Nørsett, Kristin; Lægreid, Astrid; Midelfart, Herman; Erlandsen, Sten Even; Falkmer, Sture Emil; Grønbech, Jon Erik; Waldum, Helge; Komorowski, Jan; Sandvik, Arne Kristian. (2004) Gene expression based classification of gastric carcinoma. Cancer Letters. volum 210.
Academic article
Nørsett, Kristin; Lægreid, Astrid; Midelfart, Herman; Yadetie, Fekadu; Erlandsen, Sten Even; Falkmer, Sture Emil; Grønbech, Jon Erik; Waldum, Helge; Komorowski, Jan; Sandvik, Arne Kristian. (2004) Gene expression based classification of gastric carcinoma. Cancer Letters. volum 210 (2).
Academic article
Yadetie, Fekadu; Sandvik, Arne Kristian; Bergum, Hallgeir; Nørsett, Kristin; Lægreid, Astrid. (2004) Miniaturized fluorescent RNA dot blot method for rapid quantitation of gene expression. BMC Biotechnology. volum 4.
Academic article
Yadetie, Fekadu; Sandvik, Arne Kristian; Bergum, Hallgeir; Nørsett, Kristin; Lægreid, Astrid. (2004) Miniaturized fluorescent RNA dot blot method for rapid quantitation of gene expression. BMC Biotechnology. volum 4.
Academic article
Yadetie, Fekadu; Sandvik, Arne Kristian; Bergum, Hallgeir; Nørsett, Kristin; Lægreid, Astrid. (2004) Miniaturized fluorescent RNA dot blot method for rapid quantitation of gene expression. BMC Biotechnology. volum 4.
Academic article

2003

Bakke, Ingunn; Yadetie, Fekadu; Sandvik, Arne Kristian; Kusnierczyk, W; Waldum, Helge; Lægreid, Astrid. (2003) DNA microarray analysis of liver gene expression in rats after longterm treatment with ciprofibrate. Physiological Genomics. volum 15.
Academic article
Komorowski, Jan; Lægreid, Astrid; Hvidsten, Torgeir Rhoden. (2003) Learning rule-based models from gene expression time profiles annotated using Gene Ontology. Bioinformatics. volum 19.
Academic article
Lægreid, Astrid; Hvidsten, TR; Midelfart, H; Komorowski, Jan; Sandvik, Arne Kristian. (2003) Predicting Gene Ontology Biological Prosess From Temporal Gene Expression Patterns. Genome Research.
Academic article
Nørsett, Kristin; Lægreid, Astrid; Midelfart, H; Yadetie, Fekadu; Erlandsen, S.E.; Falkmer, Sture Emil; Grønbech, Jon Erik; Waldum, Helge; Komorowski, Jan; Sandvik, Arne Kristian. (2003) Gene expression based classification of gastric carcinoma. Cancer Letters.
Academic article
Yadetie, Fekadu; Lægreid, Astrid; Bakke, I; Kusnierczyk, W; Komorowski, Jan; Waldum, Helge; Sandvik, Arne Kristian. (2003) Liver gene expression in rats in response to the peroxisome proliferator-activated receptor alpha agonist ciprofibrate. Physiological Genomics.
Academic article
Yadetie, Fekadu; Lægreid, Astrid; Bakke, Ingunn; Kusnierczyk, Waclaw; Komorowski, Jan; Waldum, Helge; Sandvik, Arne Kristian. (2003) Liver gene expression in rats in response to the peroxisome proliferator-activated receptor-{alpha} agonist ciprofibrate. Physiological Genomics. volum 15.
Academic article
Yadetie, Fekadu; Lægreid, Astrid; Bakke, Ingunn; Kusnierczyk, Waclaw; Komorowski, Jan; Waldum, Helge; Sandvik, Arne Kristian. (2003) Liver gene expression in rats in response to the peroxisome proliferator-activated receptor-alpha agonist ciprofibrate. Physiological Genomics. volum 15 (1).
Academic article

2002

Hofsli, Eva; Nørsett, Kristin; Sandvik, Arne Kristian; Lægreid, Astrid. (2002) Expression of chromogranin A and somatostatin receptors in pancreatic AR42J cells. Molecular and Cellular Endocrinology. volum 194.
Academic article
Midelfart, Herman; Komorowski, Jan; Nørsett, Kristin; Yadetie, Fekadu; Sandvik, Arne Kristian; Lægreid, Astrid. (2002) Learning Rough Set Classifiers from Gene Expressions and Clinical Data. Fundamenta Informaticae. volum 53 (2).
Academic article
Midelfart, Herman; Komorowski, Jan; Nørsett, Kristin; Yadetie, Fekadu; Sandvik, Arne Kristian; Lægreid, Astrid. (2002) Rough set classifiers from gene expressions and clinical data. Fundamenta Informaticae. volum 52.
Academic article

2001

Hvidsten, TR; Komorowski, Jan; Sandvik, Arne Kristian; Lægreid, Astrid. (2001) Predicting gene function for gene expressions and ontologies. Proceedings Pacific Symposium on Biocomputing.
Academic article
Jenssen, Tor-Kristian; Lægreid, A.; Komorowski, J.; Hovig, Eivind. (2001) A litterature network of human genes for high-throughput gene expression analysis. Nature Genetics. volum 28(1).
Academic article
Komorowski, J.; Hvidstaen, T.R.; Jenssen, Tor-Kristian; Tjedvoll, D.; Hovig, Eivind; Lægreid, A.; Sandvik, Arne K.. (2001) Mot kunnskapsoppdagelse fra DNA mikromatise uttrykksdata. Tidsskrift for Den norske legeforening. volum 121.
Academic article
Komorowski, Jan; Hvidsten, TR; Jenssen, T-K; Hovig, E; Lægreid, Astrid; Sandvik, Arne Kristian. (2001) Mot kunnskapsoppdagelse fra DNA mikromatrise (microarray) genuttrykksdata. Tidsskrift for Den norske legeforening. volum 121.
Academic article
Lægreid, Astrid; Solberg, Berge; Faxvaag, Arild. (2001) Genomforskning og genteknologi. Nye muligheiter for diagnostikkog behandling. Revmatikeren. volum 6.
Popular scientific article
Sandvik, Arne K.; Støren, O.; Nørsett, K.; Børresen-Dale, Anne-Lise; Lægreid, A.; Myklebost, Ola. (2001) Måling av genaktivitet med DNA mikromatriser (mikroarray). Molekylære og teknologiske prinsipper. Tidsskrift for Den norske legeforening. volum 121 (10).
Academic article
Sandvik, Arne K.; Støren, Ole; Nørsett, Kristin; Børresen-Dale, Anne-Lise; Lægreid, Astrid; Myklebost, Ola. (2001) Måling av genaktivitet med DNA mikromatriser (mikroarray). Molekylære og teknologiske prinsipper. Tidsskrift for Den norske legeforening. volum 121 (10).
Academic article
Sandvik, Arne Kristian; Støren, O; Nørsett, Kristin; Børresen-Dale, AL; Lægreid, Astrid; Myklebost, O. (2001) Måling av genaktivitet med DNA mikromatriser (microarray). Molekylære og teknologiske prinsipper. Tidsskrift for Den norske legeforening. volum 121.
Academic article
Lægreid, A.; Komorowski, J.; Sandvik, Arne K.; Hovig, Eivind; Forus, Anne; Smith-Sørensen, Birgitte; Beisvag, Vidar; Kristiansen, B.; Nørsett, K.; Nygaard, Vegard; Støren, O.; Myklebost, Ola. (2001) DNA mikroarray- vindu mot tusentals gen. NBS-nytt. volum 1.
Academic article

2000

Lægreid, Astrid; Komorowski, Jan; Sandvik, Arne Kristian; Hovig, Eivind; Forus, Anne; Smith-Sørensen, Birgitte; Beisvåg, Vidar; Kristiansen, Bjørn; Nørsett, Kristin; Nygaard, Vigdis; Støren, Ole; Myklebost, Ola. (2000) DNA mikroarray - vindu mot tusentals gen. NBS-nytt. volum 24 (1).
Academic article
Sandvik, Arne K.; Støren, O.; Nørsett, K.; Børresen-Dale, Anne-Lise; Lægreid, A.; Myklebost, Ola. (2000) DNA Mikroarray- molekylære og teknologiske prinsipper. Tidsskrift for Den norske legeforening.
Academic article
Thommesen, Liv; Nørsett, Kristin; Hofsli, Eva; Sandvik, AK; Lægreid, Astrid. (2000) Regulation of inducible cAMP early repressor expression by gastrin and cholecystokinin in the pancreatic cell line AR42J. Journal of Biological Chemistry. volum 275.
Academic article

1998

Thommesen, Liv; Sjursen, Wenche; Gåsvik, Kathrine; Hanssen, Wenche; Brekke, Ole-Lars; Skattebøl, Lars; Holmeide, Anne Kristin; Espevik, Terje; Johansen, Berit; Lægreid, Astrid. (1998) Selective inhibitors of cytosolic or secretory phospholipase A2 block TNF-induced activation of transcription factor nuclear factor-kappa B and expression of ICAM-1. Journal of Immunology.
Academic article

1996

Medvedev, Andrei E.; Lægreid, Astrid; Sundan, Anders; Espevik, Terje. (1996) A non-competitive P55 TNF receptor antibody enhances the specific activity of Lymphotoxin-_a. Scandinavian Journal of Immunology. volum 43 (4).
Academic article

1994

Andersen, S; Sjursen, W; Lægreid, A; Austgulen, Rigmor; Johansen, B. (1994) Immunohistologic detection of non-pancreatic phospholipase A2 (type II) in human placenta and its possible involvement in normal parturition at term. Prostaglandins, Leukotrienes and Essential Fatty Acids. volum 51.
Academic article

Journal publications

Heck, Kathleen; Lindholm, Håvard Takle; Niederdorfer, Barbara; Tsirvouli, Eirini; Kuiper, Martin; Flobak, Åsmund; Lægreid, Astrid Renner; Thommesen, Liv. (2023) Characterisation of Colorectal Cancer Cell Lines through Proteomic Profiling of Their Extracellular Vesicles. Proteomes. volum 11 (1).
Academic article
Kuiper, Martin; Bonello, Joseph; Fernández-Breis, Jesualdo Tomás; Bucher, Philipp; Futschik, Matthias E; Gaudet, Pascale; Kulakovskiy, Ivan V.; Licata, Luana; Logie, Colin; Lovering, Ruth C.; Makeev, Vsevolod J; Orchard, Sandra; Panni, Simona; Perfetto, Livia; Sant, David; Schulz, Stefan M.; Vercruysse, Steven; Zerbino, Daniel; Lægreid, Astrid. (2022) The gene regulation knowledge commons: the action area of GREEKC. Biochimica et Biophysica Acta. Gene Regulatory Mechanisms. volum 1865 (1).
Academic article
Vazquez Garcia, Miguel; Krallinger, Martin; Leitner, Florian; Kuiper, Martin; Valencia, Alfonso; Lægreid, Astrid. (2022) ExTRI: Extraction of transcription regulation interactions from literature. Biochimica et Biophysica Acta. Gene Regulatory Mechanisms. volum 1865 (1).
Academic article
Carbon, Seth J.; Douglass, Eric; Good, Benjamin M; Unni, Deepak R; Harris, Nomi L.; Mungall, Christopher J.; Basu, Siddartha; Chisholm, Rex L.; Dodson, Robert J.; Hartline, Eric; Fey, Petra; Thomas, Paul D.; Albou, Laurent-Philippe; Ebert, Dustin; Kesling, Michael J; Mi, Huaiyu; Muruganujan, Anushya; Huang, Xiaosong; Mushayahama, Tremayne. (2021) The Gene Ontology resource: enriching a GOld mine. Nucleic Acids Research (NAR).
Academic article
Gaudet, Pascale; Logie, Colin; Lovering, Ruth C.; Kuiper, Martin; Lægreid, Astrid; Thomas, Paul D.. (2021) Gene Ontology representation for transcription factor functions. Biochimica et Biophysica Acta. Gene Regulatory Mechanisms. volum 1864 (11-12).
Academic article
Juanes Cortés, Belén; Vera-Ramos, José Antonio; Lovering, Ruth C.; Gaudet, Pascale; Lægreid, Astrid; Logie, Colin; Schulz, Stefan; Roldán-García, María del Mar; Kuiper, Martin; Fernández-Breis, Jesualdo Tomás. (2021) Formalization of gene regulation knowledge using ontologies and gene ontology causal activity models. Biochimica et Biophysica Acta. Gene Regulatory Mechanisms. volum 1864 (11-12).
Academic article
Lovering, Ruth C.; Gaudet, Pascale; Acencio, Marcio Luis; Ignatchenko, Alex; Jolma, Arttu; Fornes, Oriol; Kuiper, Martin; Kulakovskiy, Ivan V.; Lægreid, Astrid; Martin, Maria J.; Logie, Colin. (2021) A GO catalogue of human DNA-binding transcription factors. Biochimica et Biophysica Acta. Gene Regulatory Mechanisms. volum 1864 (11-12).
Academic article
Folkesson, Evelina; Niederdorfer, Barbara; Nakstad, Vu To; Thommesen, Liv; Klinkenberg, Geir; Lægreid, Astrid; Flobak, Åsmund. (2020) Author Correction: High-throughput screening reveals higher synergistic effect of MEK inhibitor combinations in colon cancer spheroids (Scientific Reports, (2020), 10, 1, (11574), 10.1038/s41598-020-68441-0). Scientific Reports. volum 10 (1).
Errata
Folkesson, Evelina; Niederdorfer, Barbara; To, Vu; Thommesen, Liv; Klinkenberg, Geir; Lægreid, Astrid; Flobak, Åsmund. (2020) High-throughput screening reveals higher synergistic effect of MEK inhibitor combinations in colon cancer spheroids. Scientific Reports. volum 10.
Academic article
Niederdorfer, Barbara; Touré, Vasundra; Vazques, Miguel; Thommesen, Liv; Kuiper, Martin Tremen R.; Lægreid, Astrid; Flobak, Åsmund. (2020) Strategies to Enhance Logic Modeling-Based Cell Line-Specific Drug Synergy Prediction. Frontiers in Physiology. volum 11.
Academic article
Nydal, Rune; Bennett, Gaymon; Kuiper, Martin; Lægreid, Astrid. (2020) Silencing trust: confidence and familiarity in re-engineering knowledge infrastructures. Medicine, Health care and Philosophy.
Academic article
Touré, Vasundra; Vercruysse, Steven; Acencio, Marcio Luis; Lovering, Ruth C.; Orchard, Sandra; Bradley, Glyn; Casals-Casas, Cristina; Chaouiya, Claudine; del-Toro, Noemi; Flobak, Åsmund; Gaudet, Pascale; Hermjakob, Henning; Hoyt, Charles Tapley; Licata, Luana; Lægreid, Astrid; Mungall, Christopher; Niknejad, Anne; Panni, Simona; Perfetto, Livia. (2020) The Minimum Information about a Molecular Interaction Causal Statement (MI2CAST). Bioinformatics.
Academic article
Carbon, Seth J.; Douglass, E; Dunn, N; Good, B; Harris, NL; Lewis, SE; Mungall, CJ; Basu, S; Chisholm, RL; Dodson, RJ; Hartline, E; Fey, P; Thomas, PD; Albou, LP; Ebert, D; Kesling, MJ; Mi, H; Muruganujan, A; Huang, X. (2019) The Gene Ontology Resource: 20 years and still GOing strong. Nucleic Acids Research (NAR). volum 47 (gky1055).
Academic article
Efstathiou, Sophia; Nydal, Rune; Lægreid, Astrid; Kuiper, Martin. (2019) Scientific knowledge in the age of computation: Explicated, computable and manageable?. Theoria. An international Journal of Theory, History and Foundations of Science. volum 34 (2).
Academic article
Flobak, Åsmund; Niederdorfer, Barbara; To, Vu; Thommesen, Liv; Klinkenberg, Geir; Lægreid, Astrid. (2019) A high-throughput drug combination screen of targeted small molecule inhibitors in cancer cell lines. Scientific Data. volum 6.
Academic article
Menden, Michael Patrick; Wang, Dennis; Mason, Mike J.; Szalai, Bence; Bulusu, Krishna C.; Guan, Yuanfang; Flobak, Åsmund; Kuiper, Martin; Lægreid, Astrid; Thommesen, Liv. (2019) Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen. Nature Communications. volum 10 (2674).
Academic article
Perfetto, Livia; Acencio, Marcio Luis; Bradley, Glyn; Cesareni, Gianni; del Toro, Noemi; Fazekas, David; Hermjakob, Henning; Korcsmaros, Tamas; Kuiper, Martin; Lægreid, Astrid; Lo Surdo, Prisca; Lovering, Ruth C.; Orchard, Sandra; Porras, Pablo; Thomas, Paul; Touré, Vasundra; Zobolas, John; Licata, Luana. (2019) CausalTAB: the PSI-MITAB 2.8 updated format for signalling data representation and dissemination. Bioinformatics. volum 35 (19).
Academic article
Vera-Ramos, Jose Antonio; Juanes-Cortes, Belen; Fernández-Breis, Jesualdo Tomás; Gaudet, Pascale; Kuiper, Martin; Lægreid, Astrid; Logie, Colin; Roldan-Garcia, Maria del Mar; Schulz, Stefan. (2019) An example of multimodal biological knowledge representation. CEUR Workshop Proceedings. volum 2518.
Academic article
Flobak, Åsmund; Garcia, Miguel Vazquez; Lægreid, Astrid; Valencia, Alfonso. (2017) CImbinator: a web-based tool for drug synergy analysis in small- and large-scale datasets. Bioinformatics. volum 33 (15).
Academic article
Tripathi, Sushil; Vercruysse, Steven; Chawla, Konika; Christie, Karen R.; Blake, Judith A; Huntley, Rachael P.; Orchard, Sandra; Hermjakob, Henning; Thommesen, Liv; Lægreid, Astrid; Kuiper, Martin. (2016) Gene regulation knowledge commons: community action takes care of DNA binding transcription factors. Database: The Journal of Biological Databases and Curation.
Academic article
Flobak, Åsmund; Baudot, Anaïs; Remy, Elisabeth; Thommesen, Liv; Thieffry, Denis; Kuiper, Martin; Lægreid, Astrid. (2015) Discovery of Drug Synergies in Gastric Cancer Cells Predicted by Logical Modeling. PLoS Computational Biology. volum 11 (8).
Academic article
Tripathi, Sushil; Flobak, Åsmund; Chawla, Konika; Baudot, Anaïs; Bruland, Torunn; Thommesen, Liv; Kuiper, Martin Tremen R.; Lægreid, Astrid. (2015) The gastrin and cholecystokinin receptors mediated signaling network: a scaffold for data analysis and new hypotheses on regulatory mechanisms. BMC Systems Biology. volum 9 (40).
Academic article
Orchard, Sandra; Ammari, M; Aranda, B; Breuza, L; Briganti, L; Broackes-Carter, F; Campbell, NH; Chavali, G; Chen, C; Del-Toro, N; Duesbury, M; Dumousseau, M; Galeota, E; Hinz, U; Iannuccelli, M; Jagannathan, S; Jimenez, R.; Khadake, J; Lægreid, Astrid. (2014) The MIntAct project - IntAct as a common curation platform for 11 molecular interaction databases. Nucleic Acids Research (NAR). volum 42 (1).
Academic article
Selvik, Linn-Karina M.; Rao, Shalini; Steigedal, Tonje; Haltbakk, Ildri; Misund, Kristine; Bruland, Torunn; Prestvik, Wenche S; Lægreid, Astrid; Thommesen, Liv. (2014) Salt-inducible kinase 1 (SIK1) is induced by gastrin and inhibits migration of gastric adenocarcinoma cells. PLOS ONE. volum 9 (11).
Academic article
Venkatesan, Aravind; Tripathi, Sushil; Sanz de Galdeano, Alejandro; Blondé, Ward; Lægreid, Astrid; Mironov, Vladimir; Kuiper, Martin. (2014) Finding gene regulatory network candidates using the gene expression knowledge base. BMC Bioinformatics. volum 15 (1).
Academic article
Chawla, Konika; Tripathi, Sushil; Thommesen, Liv; Lægreid, Astrid; Kuiper, Martin. (2013) TFcheckpoint: a curated compendium of specific DNA-binding RNA polymerase II transcription factors. Bioinformatics. volum 29 (19).
Academic article
Feuerherm, Astrid Jullumstrø; Jørgensen, Katarina Mariann; Sommerfelt, Randi Magnus; Eidem, Live Egeland; Lægreid, Astrid; Johansen, Berit. (2013) Platelet-activating factor induces proliferation in differentiated keratinocytes. Molecular and Cellular Biochemistry. volum 384 (1-2).
Academic article
Misund, Kristine; Selvik, Linn-Karina M.; Rao, Shalini; Nørsett, Kristin Gabestad; Bakke, Ingunn; Sandvik, Arne; Lægreid, Astrid; Bruland, Torunn; Prestvik, Wenche S; Thommesen, Liv. (2013) NR4A2 is regulated by Gastrin and involved in gastrin-induced migration and invasion of gastric adenocarcinoma cells. PLOS ONE. volum 8 (9).
Academic article
Selvik, Linn-Karina M.; Fjeldbo, Christina Sæten; Flatberg, Arnar; Steigedal, Tonje; Misund, Kristine; Anderssen, Endre; Doseth, Berit; Langaas, Mette; Tripathi, Sushil; Beisvag, Vidar; Lægreid, Astrid; Thommesen, Liv; Bruland, Torunn. (2013) The duration of gastrin treatment affects global gene expression and molecular responses involved in ER stress and anti-apoptosis. BMC Genomics. volum 14.
Academic article
Steigedal, Tonje; Prestvik, Wenche S; Selvik, Linn-Karina M.; Fjeldbo, Christina Sæten; Bruland, Torunn; Lægreid, Astrid; Thommesen, Liv. (2013) Gastrin-induced proliferation involves MEK partner 1 (MP1). In vitro Cellular & Developmental Biology-Animal. volum 49 (3).
Academic article
Tripathi, Sushil; Christie, KR; Balakrishnan, Ravin; Huntley, R; Hill, DP; Thommesen, Liv; Blake, JA; Kuiper, Martin; Lægreid, Astrid. (2013) Gene Ontology annotation of sequence-specific DNA binding transcription factors: setting the stage for a large-scale curation effort. Database: The Journal of Biological Databases and Curation.
Academic article
Fjeldbo, Christina Sæten; Bakke, Ingunn; Erlandsen, Sten Even; Holmseth, Jannicke; Lægreid, Astrid; Sandvik, Arne Kristian; Thommesen, Liv; Bruland, Torunn. (2012) Gastrin upregulates the pro-survival factor secretory clusterin (sCLU) in adenocarcinoma cells and in oxyntic mucosa of hypergastrinemic rats. American Journal of Physiology - Gastrointestinal and Liver Physiology. volum 302 (1).
Academic article
Fjeldbo, Christina Sæten; Misund, Kristine; Günther, Clara-Cecilie; Langaas, Mette; Steigedal, Tonje; Thommesen, Liv; Lægreid, Astrid; Bruland, Torunn. (2010) Functional studies on RNA-transfected cell microarrays. Methods in molecular biology. volum 629.
Academic article
Jørgensen, Katarina; Felberg, Hanne Solvang; Berge, Rolf K.; Lægreid, Astrid; Johansen, Berit. (2010) Platelet activating factor stimulates arachidonic acid release in differentiated keratinocytes via arachidonyl non-selective phospholipase A(2). Archives of Dermatological Research. volum 302 (3).
Academic article
Hvidsten, Torgeir; Lægreid, Astrid; Kryshtafovych, Andriy; Andersson, Gunnar; Fidelis, Krzysztof; Komorowski, J. (2009) A comprehensive analysis of the structure-function relationship in proteins based on local structure similarity. PLOS ONE. volum 4 (7).
Academic article
Fjeldbo, Christina Sæten; Misund, Kristine; Günther, Clara-Cecilie; Langaas, Mette; Steigedal, Tonje Strømmen; Thommesen, Liv; Lægreid, Astrid; Bruland, Torunn. (2008) Functional studies on transfected cell microarray analysed by linear regression modelling. Nucleic Acids Research (NAR). volum 36 (15).
Academic article
Fjeldbo, Christina Sæten; Misund, Kristine; Gunther, Clara-Cecilie; Langaas, Mette; Steigedal, Tonje; Thommesen, Liv; Lægreid, Astrid; Bruland, Torunn. (2008) Functional studies on transfected cell microarray analysed by linear regression modelling. Nucleic Acids Research (NAR). volum 36 (15).
Academic article
Hofsli, Eva; Wheeler, Tom Even; Langaas, Mette; Lægreid, Astrid; Thommesen, Liv. (2008) Identification of novel neuroendocrine-specific tumour genes. British Journal of Cancer. volum 99 (8).
Academic article
Hofsli, Eva; Wheeler, Tommy L.; Langaas, Mette; Lægreid, Astrid; Thommesen, Liv. (2008) Identification of novel neuroendocrine-specific tumour genes. British Journal of Cancer. volum 99 (8).
Academic article
Nørsett, Kristin; Lægreid, Astrid; Kusnierczyk, Waclaw; Langaas, Mette; Ylving, S; Fossmark, Reidar; Myhre, Simen; Falkmer, Sture Emil; Waldum, Helge; Sandvik, Arne Kristian. (2008) Changes in gene expression of gastric mucosa during therapeutic acid inhibition. European Journal of Gastroenterology and Hepathology. volum 20.
Academic article
Bruland, Torunn; Anderssen, Endre; Eitrem, Berit Doseth; Bergum, Hallgeir; Beisvåg, Vidar; Lægreid, Astrid. (2007) Optimization of cDNA microarrays procedures using criteria that do not rely on external standards. BMC Genomics. volum 8 (1).
Academic article
Misund, Kristine; Steigedal, Tonje Strømmen; Lægreid, Astrid; Thommesen, Liv. (2007) Inducible cAMP early repressor splice variants ICER I and IIgamma both repress transcription of c-fos and chromogranin A. Journal of Cellular Biochemistry. volum 101 (6).
Academic article
Misund, Kristine; Steigedal, Tonje; Lægreid, Astrid; Thommesen, Liv. (2007) Inducible cAMP early repressor splice variants ICER I and II gamma both repress transcription of c-fos and chromogranin A. Journal of Cellular Biochemistry. volum 101.
Academic article
Steigedal, Tonje Strømmen; Bruland, Torunn; Misund, Kristine; Thommesen, Liv; Lægreid, Astrid. (2007) Inducible cAMP early repressor suppresses gastrin-mediated activation of cyclin D1 and c-fos gene expression. American Journal of Physiology - Gastrointestinal and Liver Physiology. volum 292 (4).
Academic article
Steigedal, Tonje; Bruland, Torunn; Misund, Kristine; Thommesen, Liv; Lægreid, Astrid. (2007) Inducible cAMP early repressor suppresses gastrin-mediated activation of cyclin D1 and c-fos gene expression. American Journal of Physiology - Gastrointestinal and Liver Physiology. volum 292 (4).
Academic article
Beisvag, Vidar; Lehre, PK; Midelfart, H; Aas, Halfdan; Geiran, Odd; Sandvik, Arne K; Lægreid, A.; Komorowski, J.; Ellingsen, Øyvind. (2006) Aetiology-specific patterns in end-stage heart failure patients identified by functional annotation and classification of microarray data. European Journal of Heart Failure. volum 8 (4).
Academic article
Beisvåg, Vidar; Jünge, Frode KR; Bergum, Hallgeir; Jølsum, Lars; Lydersen, Stian; Gunther, Clara-Cecilie; Ramampiaro, Heri; Langaas, Mette; Sandvik, Arne Kristian; Lægreid, Astrid. (2006) GeneTools - application for functional annotation and statistical hypothesis testing. BMC Bioinformatics. volum 7 (470).
Book review
Beisvåg, Vidar; Lehre, Per Kristian; Midelfart, Herman; Aass, H; Geiran, O; Sandvik, Arne Kristian; Lægreid, Astrid; Komorowski, Jan; Ellingsen, Øyvind. (2006) Aetiology-specific patterns in end-stage heart failure patients identified by functional annotation and classification of microarray data. European Journal of Heart Failure. volum 8.
Academic article
Myhre, S; Tveit, Henrik; Mollestad, Torulf; Lægreid, Astrid. (2006) Additional Gene Ontology structure for improved biological reasoning. Bioinformatics. volum 22 (16).
Academic article
Sandvik, Arne Kristian; Alsberg, Bjørn Kåre; Nørsett, Kristin; Yadetie, Fekadu; Waldum, Helge; Lægreid, Astrid. (2006) Gene expression analysis and clinical diagnosis. Clinica Chimica Acta. volum 363.
Academic literature review
Hofsli, Eva; Thommesen, Liv; Yadetie, Fekadu; Langaas, Mette; Sandvik, Arne K.; Lægreid, Astrid. (2005) Identification of novel growth factor-responsive genes in neuroendocrine gastrointestinal tumour cells. British Journal of Cancer. volum 92 (8).
Academic article
Sætre, Rune; Tveit, Amund; Ranang, Martin Thorsen; Strømmen, Tonje; Thommesen, Liv; Stunes, Astrid Kamilla; Lægreid, Astrid. (2005) gProt: Annotating Protein Interactions Using Google and Gene Ontology. Lecture Notes in Computer Science (LNCS). volum 3683.
Academic article
Thommesen, Liv; Lægreid, Astrid. (2005) Distinct differences between TNF receptor 1-and TNF receptor 2-mediated activation of NF kappa B. Journal of Biochemistry and Molecular Biology. volum 38.
Academic article
Tveit, Amund; Sætre, Rune; Strømmen, Tonje; Lægreid, Astrid. (2005) ProtChew: Automatic Extraction of Protein Names from Biomedical Literature. Proceedings - International Conference on Data Engineering.
Academic article
Hofsli, Eva; Thommesen, Liv; Yadetie, Fekadu; Langaas, Mette; Kusnierczyk, Waclaw; Falkmer, Ursula; Sandvik, Arne Kristian; Lægreid, Astrid. (2005) Identification of novel growth factor-responsive genes in neuroendocrine gastrointestinal tumour cells. British Journal of Cancer. volum 92.
Academic article
Nørsett, Kristin; Lægreid, Astrid; Langaas, Mette; Wørlund, Sara Maria; Fossmark, Reidar; Waldum, Helge; Sandvik, Arne Kristian. (2005) Molecular characterization of rat gastric mucosal response to potent acid inhibition. Physiological Genomics. volum 22.
Academic article
Sandvik, Arne Kristian; Alsberg, Bjørn Kåre; Nørsett, Kristin; Yadetie, Fekadu; Waldum, Helge; Lægreid, Astrid. (2005) Gene expression analysis and clinical diagnosis. Clinica Chimica Acta.
Academic literature review
Sætre, Rune; Tveit, Amund; Strømmen, Tonje; Lægreid, Astrid. (2005) Semantic annotation of biomedical literature using Google. Lecture Notes in Computer Science (LNCS). volum 3482 (3).
Academic article
Thommesen, Liv; Lægreid, Astrid. (2005) Distinct differences between TNF receptor 1-and TNF receptor 2-mediated activation of NF kappa B. Journal of Biochemistry and Molecular Biology. volum 38 (3).
Academic article
Flikka, K; Lægreid, Astrid. (2004) XHM: A system for detection of potential cross hybridizations in DNA microarrays. BMC Bioinformatics.
Academic article
Flikka, Kristian; Yadetie, Fekadu; Lægreid, Astrid; Jonassen, Inge. (2004) XHM: A system for detection of potential cross hybridizations in DNA microarrays. BMC Bioinformatics. volum 5.
Academic article
Flikka, Kristian; Yadetie, Fekadu; Lægreid, Astrid; Jonassen, Inge. (2004) XHM: a system for detection of potential cross hybridizations in DNA microarrays. BMC Bioinformatics. volum 5 (117).
Academic article
Flikka, Kristian; Yadetie, Fekadu; Lægreid, Astrid; Jonassen, Inge. (2004) XHM: a system for detection of potential cross hybridizations in DNA microarrays. BMC Bioinformatics. volum 5 (117).
Academic article
Nørsett, Kristin; Lægreid, Astrid; Midelfart, Herman; Erlandsen, Sten Even; Falkmer, Sture Emil; Grønbech, Jon Erik; Waldum, Helge; Komorowski, Jan; Sandvik, Arne Kristian. (2004) Gene expression based classification of gastric carcinoma. Cancer Letters. volum 210.
Academic article
Nørsett, Kristin; Lægreid, Astrid; Midelfart, Herman; Yadetie, Fekadu; Erlandsen, Sten Even; Falkmer, Sture Emil; Grønbech, Jon Erik; Waldum, Helge; Komorowski, Jan; Sandvik, Arne Kristian. (2004) Gene expression based classification of gastric carcinoma. Cancer Letters. volum 210 (2).
Academic article
Yadetie, Fekadu; Sandvik, Arne Kristian; Bergum, Hallgeir; Nørsett, Kristin; Lægreid, Astrid. (2004) Miniaturized fluorescent RNA dot blot method for rapid quantitation of gene expression. BMC Biotechnology. volum 4.
Academic article
Yadetie, Fekadu; Sandvik, Arne Kristian; Bergum, Hallgeir; Nørsett, Kristin; Lægreid, Astrid. (2004) Miniaturized fluorescent RNA dot blot method for rapid quantitation of gene expression. BMC Biotechnology. volum 4.
Academic article
Yadetie, Fekadu; Sandvik, Arne Kristian; Bergum, Hallgeir; Nørsett, Kristin; Lægreid, Astrid. (2004) Miniaturized fluorescent RNA dot blot method for rapid quantitation of gene expression. BMC Biotechnology. volum 4.
Academic article
Bakke, Ingunn; Yadetie, Fekadu; Sandvik, Arne Kristian; Kusnierczyk, W; Waldum, Helge; Lægreid, Astrid. (2003) DNA microarray analysis of liver gene expression in rats after longterm treatment with ciprofibrate. Physiological Genomics. volum 15.
Academic article
Komorowski, Jan; Lægreid, Astrid; Hvidsten, Torgeir Rhoden. (2003) Learning rule-based models from gene expression time profiles annotated using Gene Ontology. Bioinformatics. volum 19.
Academic article
Lægreid, Astrid; Hvidsten, TR; Midelfart, H; Komorowski, Jan; Sandvik, Arne Kristian. (2003) Predicting Gene Ontology Biological Prosess From Temporal Gene Expression Patterns. Genome Research.
Academic article
Nørsett, Kristin; Lægreid, Astrid; Midelfart, H; Yadetie, Fekadu; Erlandsen, S.E.; Falkmer, Sture Emil; Grønbech, Jon Erik; Waldum, Helge; Komorowski, Jan; Sandvik, Arne Kristian. (2003) Gene expression based classification of gastric carcinoma. Cancer Letters.
Academic article
Yadetie, Fekadu; Lægreid, Astrid; Bakke, I; Kusnierczyk, W; Komorowski, Jan; Waldum, Helge; Sandvik, Arne Kristian. (2003) Liver gene expression in rats in response to the peroxisome proliferator-activated receptor alpha agonist ciprofibrate. Physiological Genomics.
Academic article
Yadetie, Fekadu; Lægreid, Astrid; Bakke, Ingunn; Kusnierczyk, Waclaw; Komorowski, Jan; Waldum, Helge; Sandvik, Arne Kristian. (2003) Liver gene expression in rats in response to the peroxisome proliferator-activated receptor-{alpha} agonist ciprofibrate. Physiological Genomics. volum 15.
Academic article
Yadetie, Fekadu; Lægreid, Astrid; Bakke, Ingunn; Kusnierczyk, Waclaw; Komorowski, Jan; Waldum, Helge; Sandvik, Arne Kristian. (2003) Liver gene expression in rats in response to the peroxisome proliferator-activated receptor-alpha agonist ciprofibrate. Physiological Genomics. volum 15 (1).
Academic article
Hofsli, Eva; Nørsett, Kristin; Sandvik, Arne Kristian; Lægreid, Astrid. (2002) Expression of chromogranin A and somatostatin receptors in pancreatic AR42J cells. Molecular and Cellular Endocrinology. volum 194.
Academic article
Midelfart, Herman; Komorowski, Jan; Nørsett, Kristin; Yadetie, Fekadu; Sandvik, Arne Kristian; Lægreid, Astrid. (2002) Learning Rough Set Classifiers from Gene Expressions and Clinical Data. Fundamenta Informaticae. volum 53 (2).
Academic article
Midelfart, Herman; Komorowski, Jan; Nørsett, Kristin; Yadetie, Fekadu; Sandvik, Arne Kristian; Lægreid, Astrid. (2002) Rough set classifiers from gene expressions and clinical data. Fundamenta Informaticae. volum 52.
Academic article
Hvidsten, TR; Komorowski, Jan; Sandvik, Arne Kristian; Lægreid, Astrid. (2001) Predicting gene function for gene expressions and ontologies. Proceedings Pacific Symposium on Biocomputing.
Academic article
Jenssen, Tor-Kristian; Lægreid, A.; Komorowski, J.; Hovig, Eivind. (2001) A litterature network of human genes for high-throughput gene expression analysis. Nature Genetics. volum 28(1).
Academic article
Komorowski, J.; Hvidstaen, T.R.; Jenssen, Tor-Kristian; Tjedvoll, D.; Hovig, Eivind; Lægreid, A.; Sandvik, Arne K.. (2001) Mot kunnskapsoppdagelse fra DNA mikromatise uttrykksdata. Tidsskrift for Den norske legeforening. volum 121.
Academic article
Komorowski, Jan; Hvidsten, TR; Jenssen, T-K; Hovig, E; Lægreid, Astrid; Sandvik, Arne Kristian. (2001) Mot kunnskapsoppdagelse fra DNA mikromatrise (microarray) genuttrykksdata. Tidsskrift for Den norske legeforening. volum 121.
Academic article
Lægreid, Astrid; Solberg, Berge; Faxvaag, Arild. (2001) Genomforskning og genteknologi. Nye muligheiter for diagnostikkog behandling. Revmatikeren. volum 6.
Popular scientific article
Sandvik, Arne K.; Støren, O.; Nørsett, K.; Børresen-Dale, Anne-Lise; Lægreid, A.; Myklebost, Ola. (2001) Måling av genaktivitet med DNA mikromatriser (mikroarray). Molekylære og teknologiske prinsipper. Tidsskrift for Den norske legeforening. volum 121 (10).
Academic article
Sandvik, Arne K.; Støren, Ole; Nørsett, Kristin; Børresen-Dale, Anne-Lise; Lægreid, Astrid; Myklebost, Ola. (2001) Måling av genaktivitet med DNA mikromatriser (mikroarray). Molekylære og teknologiske prinsipper. Tidsskrift for Den norske legeforening. volum 121 (10).
Academic article
Sandvik, Arne Kristian; Støren, O; Nørsett, Kristin; Børresen-Dale, AL; Lægreid, Astrid; Myklebost, O. (2001) Måling av genaktivitet med DNA mikromatriser (microarray). Molekylære og teknologiske prinsipper. Tidsskrift for Den norske legeforening. volum 121.
Academic article
Lægreid, A.; Komorowski, J.; Sandvik, Arne K.; Hovig, Eivind; Forus, Anne; Smith-Sørensen, Birgitte; Beisvag, Vidar; Kristiansen, B.; Nørsett, K.; Nygaard, Vegard; Støren, O.; Myklebost, Ola. (2001) DNA mikroarray- vindu mot tusentals gen. NBS-nytt. volum 1.
Academic article
Lægreid, Astrid; Komorowski, Jan; Sandvik, Arne Kristian; Hovig, Eivind; Forus, Anne; Smith-Sørensen, Birgitte; Beisvåg, Vidar; Kristiansen, Bjørn; Nørsett, Kristin; Nygaard, Vigdis; Støren, Ole; Myklebost, Ola. (2000) DNA mikroarray - vindu mot tusentals gen. NBS-nytt. volum 24 (1).
Academic article
Sandvik, Arne K.; Støren, O.; Nørsett, K.; Børresen-Dale, Anne-Lise; Lægreid, A.; Myklebost, Ola. (2000) DNA Mikroarray- molekylære og teknologiske prinsipper. Tidsskrift for Den norske legeforening.
Academic article
Thommesen, Liv; Nørsett, Kristin; Hofsli, Eva; Sandvik, AK; Lægreid, Astrid. (2000) Regulation of inducible cAMP early repressor expression by gastrin and cholecystokinin in the pancreatic cell line AR42J. Journal of Biological Chemistry. volum 275.
Academic article
Thommesen, Liv; Sjursen, Wenche; Gåsvik, Kathrine; Hanssen, Wenche; Brekke, Ole-Lars; Skattebøl, Lars; Holmeide, Anne Kristin; Espevik, Terje; Johansen, Berit; Lægreid, Astrid. (1998) Selective inhibitors of cytosolic or secretory phospholipase A2 block TNF-induced activation of transcription factor nuclear factor-kappa B and expression of ICAM-1. Journal of Immunology.
Academic article
Medvedev, Andrei E.; Lægreid, Astrid; Sundan, Anders; Espevik, Terje. (1996) A non-competitive P55 TNF receptor antibody enhances the specific activity of Lymphotoxin-_a. Scandinavian Journal of Immunology. volum 43 (4).
Academic article
Andersen, S; Sjursen, W; Lægreid, A; Austgulen, Rigmor; Johansen, B. (1994) Immunohistologic detection of non-pancreatic phospholipase A2 (type II) in human placenta and its possible involvement in normal parturition at term. Prostaglandins, Leukotrienes and Essential Fatty Acids. volum 51.
Academic article

Part of book/report

Nydal, Rune; Efstathiou, Sophia; Lægreid, Astrid. (2012) Crossover Research: Exploring a Collaborative Mode of Integration. Little by Little. Expansions of Nanoscience and Emerging Technologies.
Academic chapter/article/Conference paper
Lægreid, Astrid; Feilberg, Julie. (2009) Using the classification system for institutional profiling : the Norwegian University of Science and technology. Mapping the Higher Education Landscape :.
Academic chapter/article/Conference paper
Sætre, Rune; Ranang, Martin Thorsen; Steigedal, Tonje Strømmen; Stunes, Kamilla; Misund, Kristine; Thommesen, Liv; Lægreid, Astrid. (2007) Webprot : online mining and annotation of biomedical literature using Google. Advanced computational methods for biocomputing and bioimaging.
Academic chapter/article/Conference paper
Kusnierczyk, Waclaw; Aamodt, Agnar; Lægreid, Astrid. (2005) Knowledge-Intensive Case-Based Support for Automated Explanation of Biological Phenomena. 6th International Conference on Case-Based Reasoning (ICCBR 2005), 23-26 August 2005. Workshop Proceedings.
Academic chapter/article/Conference paper
Sætre, Rune; Tveit, Amund; Ranang, Martin Thorsen; Steigedal, Tonje Strømmen; Thommesen, Liv; Stunes, Kamilla; Lægreid, Astrid. (2005) gProt: Annotating protein interactions using Google and Gene Ontology. Lecture Notes in Computer Science.
Academic chapter/article/Conference paper
Drabløs, Finn; Hammer, Mikael; Lægreid, Astrid; Hauglid, Jon Olav; Alsberg, Bjørn Kåre. (2004) Bioinformatics. Infosam2020, Information Society of 2020.
Academic chapter/article/Conference paper

INFORMASJONSMATR

Lægreid, Astrid; Kuiper, Martin. (2015) Health and the information commons.
Website (informational material)
Lægreid, Astrid; Kuiper, Martin. (2014) Å ta seg av kunnskap.
Website (informational material)

Teaching

Courses

Media

2018

Academic lecture

Acencio, Marcio Luis; Krallinger, Martin; Kuiper, Martin; Lægreid, Astrid. (2018) Mining DbTF-TG causal interactions from biomedical literature. GREEKC CA15205: Ontologies for the Gene Regulation Knowledge Commons, and Database 'FAIRness' Short description: ; 2018-10-01 - 2018-10-02.
Lecture

Niederdorfer, Barbara; Vázquez, Miguel; Thommesen, Liv; Kuiper, Martin; Lægreid, Astrid; Flobak, Åsmund. (2018) Logical model simulations predict drug synergies across different cancer cell lines. ISMB 2018 . International Society for Computational Biology; Chicago. 2018-07-06 - 2018-07-10.
Academic lecture

Nydal, Rune; Lægreid, Astrid; Kuiper, Martin; Gabrielsen, Ane Møller. (2018) Introduction. Visions for Life Science Knowledge Commons. Visions for Life Science Knowledge Commons . Crossover project; Trondheim. 2018-05-23 - 2018-05-24.
Poster

Touré, Vasundra; Flobak, Åsmund; Lægreid, Astrid; Kuiper, Martin. (2018) Knowledge management and standard representation of causal statements for systems modeling. JOBIM 2018 ; Marseille. 2018-07-03 - 2018-07-06.

2017

Academic lecture

Acencio, Marcio Luis; Lægreid, Astrid. (2017) Representation of sequence-specific DNA binding transcription factors (DbTFs) complexes. Curation workshop on molecular and causal interactions ; 2017-12-05 - 2017-12-07.
Lecture

Acencio, Marcio Luis; Lægreid, Astrid; Kuiper, Martin; Thommesen, Liv; Leitner, Florian; Krallinger, Martin; Lourenço, Analia; Vázquez, Miguel; Valencia, Alfonso. (2017) NTNU DbTF Curation: current status and Mining Transcription Regulation Information from Literature. Short Research Stay at the European Bioinformatics Institute (EBI) ; Hinxton, Cambridge. 2017-05-08 - 2017-05-10.
Academic lecture

Acencio, Marcio Luis; Vázquez, Miguel; Kuiper, Martin; Lægreid, Astrid. (2017) DbTF-TG interactions and regulatory relationships: a survey. Curation workshop on molecular and causal interactions ; 2017-12-05 - 2017-12-07.
Poster

Touré, Vasundra; Flobak, Åsmund; Lægreid, Astrid; Kuiper, Martin Tremen R.. (2017) Extraction and representation of causal statements: Creating a model building resource for Systems Biology. COMBINE 2017 . COMBINE 2017; Milano. 2017-10-09 - 2017-10-13.

2016

Lecture

Acencio, Marcio Luis; Lægreid, Astrid; Kuiper, Martin. (2016) Causal statements for Gene Regulation & Signal Transduction: what can be done in PSI-MI. HUPO-PSI meeting 2016 ; 2016-04-18 - 2016-04-20.
Lecture

Acencio, Marcio Luis; Lægreid, Astrid; Kuiper, Martin. (2016) Knowledge Commons digitalization - curation. Crossover Seminar ; 2016-04-14 - 2016-04-15.
Poster

Flobak, Åsmund; Steigedal, Tonje S.; Thommesen, Liv; Kuiper, Martin Tremen R.; Lægreid, Astrid. (2016) Logical models for drug screen prioritization. European Conference on Computational Biology . European Conference on Computational Biology; Den Haag. 2016-09-03 - 2016-09-07.
Academic lecture

Lægreid, Astrid. (2016) Why we need the Knowledge Commons. Today's biology is not possible without. Science for the common good – visions of technological opportunities . NTNU/Crossover/Reset; Trondheim. 2016-06-13 - 2016-06-14.
Academic lecture

Nydal, Rune; Lægreid, Astrid; Kuiper, Martin. (2016) Curation strategeis of NTNU project. Workshop upstart crossover at EBI . EBI and Crossover; EBI. 2016-04-22 - 2016-04-23.

2014

Poster

Flobak, Åsmund; Baudot, Anaïs; Remy, Elisabeth; Thommesen, Liv; Thieffry, Denis; Kuiper, Martin; Lægreid, Astrid. (2014) Drug synergies in a gastric cancer cell line discovered by signal transduction modeling. Virtual Physiological Human Conference 2014 . Stig Omholt / VPH consortium; Trondheim. 2014-09-09 - 2014-09-12.
Poster

Kuiper, Martin; Lægreid, Astrid. (2014) The GRECO initiative: taking care of Gene Regulation knowledge. Virtual Physiological Human Conference 2014 . Stig Omholt / VPH consortium; Trondheim. 2014-09-09 - 2014-09-12.
Poster

Kuiper, Martin; Mironov, Vladimir; Venkatesan, Aravind; Tripathi, Sushil; Blondé, Ward; Sanz de Galdeano, Alejandro; Lægreid, Astrid. (2014) The gene expression knowledge base. Virtual Physiological Human Conference 2014 . Stig Omholt / VPH consortium; Trondheim. 2014-09-09 - 2014-09-12.
Lecture

Nydal, Rune; Efstathiou, Sophia; Lægreid, Astrid; Kuiper, Martin. (2014) Setting the stage: Tragedy of the knowledge commons. Knowledge management and the futures of our society, a Virtual Physiological Human 2014 Satellite Workshop . Crossover research group NTNU; Trondheim. 2014-09-08 - 2014-09-09.
Poster

Vange, Pål; Beisvag, Vidar; Flatberg, Arnar; Afroz, Wahida; Nordrum, Ivar Skjåk; Sørdal, Øystein Finset; Qvigstad, Gunnar; Thommesen, Liv; Lægreid, Astrid; Sandvik, Arne Kristian; Bruland, Torunn; Bakke, Ingunn. (2014) Molecular mechanisms of cellular stress responses in gastric cancer. Digestive Disease Week 2014 . AASLD, AGA, ASGE, SSAT; Chicago. 2014-05-03 - 2014-05-06.

2013

Poster

Rao, Shalini; Selvik, Linn-Karina M.; Nørsett, Kristin Gabestad; Bakke, Ingunn; Misund, Kristine; Bruland, Torunn; Wenche S, Prestvik; Lægreid, Astrid; Thommesen, Liv. (2013) NR4A2 is regulated by gastrin and influences cellular responses in gastric adenocarcinoma cells. Nuclear receptors: Linking molecules, genomes & physiology . EMBO Conference; Sorrento. 2013-09-06 - 2013-09-10.
Poster

Rao, Shalini; Thommesen, Liv; Nørsett, Kristin; Bakke, Ingunn; Misund, Kristine; Bruland, Torunn; Prestvik, Wenche S; Lægreid, Astrid. (2013) Nr4A2 is regulated by gastrin and influences cellular responses in gastric adenocarcinoma cells. Kontaktmøte Norsk Biokjemisk Selskap . NBS Sør-Trøndelag; Røros. 2013-01-17 - 2013-01-20.

2012

Academic lecture

Efstathiou, Sophia; Carusi, Annamaria; Kuiper, Martin; Lægreid, Astrid; Nydal, Rune. (2012) Research Systems for Systems Biology. European Meetings on Cybernetics and Systems Research . Austrian Society for Cybernetic Studies; Vienna. 2012-04-10 - 2012-04-13.
Academic lecture

Efstathiou, Sophia; Nydal, Rune; Carusi, Annamaria; Kuiper, Martin; Lægreid, Astrid. (2012) Well-constructed systems biology: Integrating socio-humanist research. European Meetings on Cybernetics and Systems Research ; AUSTRIA. 2012-04-12 - 2012-04-14.
Academic lecture

Efstathiou, Sophia; Nydal, Rune; Kuiper, Martin; Lægreid, Astrid; Carusi, Annamaria. (2012) When ‘Knowledge’ Becomes Something to Manage. Society for the Study of Nanoscience and Emerging Technologies ; 2012-10-23 - 2012-10-25.
Academic lecture

Nydal, Rune; Efstathiou, Sophia; Lægreid, Astrid. (2012) Widening the circles of collaboration - Integrating philosophy in systems biology. Fourth Annual converence of the society for the study of nanoscience and emerging technologies . Soc. for the study of nanoscience and emerging technologies; Twente. 2012-10-22 - 2012-10-25.

2011

Academic lecture

Nydal, Rune; Efstathiou, Sophia; Lægreid, Astrid. (2011) Well-constructed systems biology. Integrating Socio-humanist Research. S-Net, Third annual meeting . Soc. for the Study of Nanoscience and Emerging Technologies; Tempe, Arizona. 2011-11-07 - 2011-11-10.
Poster

Tripathi, Sushil; Venkatesan, Aravind; Egaña, Mikel; Zavareh, Zahra; Chawla, Konika; Mironov, Vladimir; Thommesen, Liv; Bruland, Torunn; Kuiper, Martin; Lægreid, Astrid. (2011) Automated Assessment of High Throughput Hypotheses on Gene Regulatory Mechanisms Involved in the Gastrin Response. Bio-Ontologies 2011 . ISMB 2011; Vienna. 2011-07-15 - 2011-07-16.

2010

Poster

Bruland, Torunn; Anderssen, Endre; Misund, Kristine; Fjeldbo, Christina Sæten; Flatberg, Arnar; Selvik, Linn-Karina M.; Beisvag, Vidar; Sandvik, Arne Kristian; Lægreid, Astrid; Thommesen, Liv. (2010) Exploring signal-induced cellular regulatory subnetworks by use of partial least square regression (PLSR) multidimensional analysis of gene expression time series data. 13th Annual MGED meeting , Boston, Massachusetts, USA . The MGED Society; Boston. 2010-07-13 - 2010-07-15.
Poster

Tripathi, Sushil; Thommesen, Liv; Skjøndal-Bar, Nadav; Almaas, Eivind; Kuiper, Martin; Lægreid, Astrid. (2010) Modelling the gastrin signalling pathways. 11th International Conference on Systems Biology ; Edinburgh. 2010-10-10 - 2010-10-16.
Poster

Tripathi, Sushil; Thommesen, Liv; Skjøndal-Bar, Nadav; Almaas, Eivind; Kuiper, Martin; Lægreid, Astrid. (2010) Modelling the gastrin signalling pathways. 22nd International Conference of the Society for Medical Innovation and Technology ; Trondheim. 2010-09-02 - 2010-09-04.

2009

Poster

Anderssen, Endre; Bruland, Torunn; Misund, Kristine; Sandvik, Arne K.; Thommesen, Liv; Lægreid, Astrid. (2009) Using basic networks motifs and biological background knowledge to analyze transcriptomic time series data. MGED Meeting ; Phoenix, USA. 2009-10-05 - 2009-10-08.
Poster

Bruland, Torunn; Anderssen, Endre; Misund, Kristine; Beisvåg, Vidar; Sandvik, Arne K.; Lægreid, Astrid; Thommesen, Liv. (2009) Discovering basic network motifs that underlie gastrin induced gene expression. 10th international conference on system biology ; San Francisco. 2009-08-30 - 2009-09-04.
Poster

Bruland, Torunn; Anderssen, Endre; Misund, Kristine; Beisvag, Vidar; Sandvik, Arne Kristian; Thommesen, Liv; Lægreid, Astrid. (2009) Discovering basic network motifs that underlie gastrin induced gene expression. The 10th International Conference on System Biology ICSB-2009, USA . ICSB; Standford, Calefornia. 2009-08-30 - 2009-09-04.
Academic lecture

Bruland, Torunn; Anderssen, Endre; Misund, Kristine; Steigedal, Tonje Strømmen; Doseth, Berit; Langaas, Mette; Bergum, Hallgeir; Lægreid, Astrid; Thommesen, Liv. (2009) Basic common architectural motifs underlying gastrin induced gene expression can be identified by dimension reduction methods. Contact Meeting NBS ; Røros. 2009-01-22 - 2009-01-25.
Academic lecture

Bruland, Torunn; Anderssen, Endre; Misund, Kristine; Steigedal, Tonje; Doseth, Berit; Fjeldbo, Christina Sæten; Langaas, Mette; Bergum, Hallgeir; Lægreid, Astrid; Thommesen, Liv. (2009) Basic common architectural motifs underlying gastrin induced gene expression can be identified by dimention reduction methods. NBS 43. Contact Meeting . NBS Trondheim; Røros. 2009-01-17 - 2009-01-20.
Academic lecture

Selvik, Linn-Karina M.; Misund, Kristine; Fjeldbo, Christina Sæten; Steigedal, Tonje; Bruland, Torunn; Lægreid, Astrid; Thommesen, Liv. (2009) Salt-inducible kinase 1 (SIK1) is involved in the gastrin-mediated growth response and is repressed by ICER and Zfp36l1. NBS Kontaktmøte 2009 . NBS; Røros. 2009-01-29 - 2009-02-01.
Academic lecture

Thommesen, Liv; Misund, Kristine; Selvik, Linn Karina Myrland; Lægreid, Astrid; Bruland, Torunn. (2009) NR4A" (Nurr1) - involved in gastrin-mediated carcinogenesis?. Contact meeting NBS ; Røros. 2009-01-22 - 2009-01-25.

2008

Poster

Bruland, Torunn; Andersen, Endre; Misund, Kristine; Steigedal, Tonje Strømmen; Fjeldbo, Christina Sæten; Lægreid, Astrid; Thommesen, Liv. (2008) Molecular mecanisms in cancer-related gastrin responses. Cancer Epigenetics ; Boston. 2008-05-28 - 2008-05-31.
Poster

Bruland, Torunn; Anderssen, Endre; Misund, Kristine; Steigedal, Tonje Strømmen; Doseth, Berit; Fjeldbo, Christina Sæten; Langaas, Mette; Bergum, Hallgeir; Lægreid, Astrid; Thommesen, Liv. (2008) Significance analysis of gastrin-mediated transcription using dimension reduction methods for interpreting and modelling DNA microarray time series gene expression data. ESF Functional Genomics and Disease ; Innsbruck. 2008-10-01 - 2008-10-05.
Poster

Bruland, Torunn; Anderssen, Endre; Misund, Kristine; Steigedal, Tonje; Doseth, Berit; Fjeldbo, Christina Sæten; Langaas, Mette; Bergum, Hallgeir; Lægreid, Astrid; Thommesen, Liv. (2008) Significance analysis of gastrin-mediated transcription using dimension reduction methods for interpreting and modelling DNA microarray time series gene expression. 3rd ESF Functional Genomics Conference; Functional genomics and disease ; Insnsbruck. 2008-10-01 - 2008-10-04.
Poster

Bruland, Torunn; Anderssen, Endre; Misund, Kristine; Steigedal, Tonje; Doseth, Berit; Fjeldbo, Christina Sæten; Lægreid, Astrid; Thommesen, Liv. (2008) Molecular mechanisms in cancer related gastrin responses. Cancer Epigenetics Conference . American Association for Cancer Research; Boston. 2008-05-28 - 2008-05-31.
Poster

Selvik, Linn-Karina M.; Misund, Kristine; Fjeldbo, Christina Sæten; Steigedal, Tonje Strømmen; Bruland, Torunn; Lægreid, Astrid; Thommesen, Liv. (2008) Salt-inducible kinase 1 (SIK1) is involved in the gastrin-mediated growth response. ESF Functional Genomics and Disease ; Innsbruck. 2008-10-01 - 2008-10-05.
Poster

Selvik, Linn-Karina M.; Misund, Kristine; Fjeldbo, Christina Sæten; Steigedal, Tonje; Bruland, Torunn; Lægreid, Astrid; Thommesen, Liv. (2008) Salt-inducible kinase 1 (SIK1) is involved in the gastrin-mediated growth response. ESF Functional Genomics and Disease Conference ; Innsbruck. 2008-10-01 - 2008-10-04.

2007

Popular scientific lecture

Gether, Harald; Moe, Geir; Nilssen, Robert; Undeland, Tore Marvin; Nielsen, Kai Olav; Karstad, Per Ivar; Lægreid, Astrid. (2007) Ren energi til ren industri. Invitert møte i for departementene (OED, ND, MD) . Dep; Oslo. 2007-06-12.
Poster

Misund, Kristine; Bruland, Torunn; Anderssen, Endre; Lægreid, Astrid; Thommesen, Liv. (2007) Global gene expression in HEK 293 cells with controllable ICER I and II gamma overexpression. NBS kontaktmøte 2007 ; Lillehammer. 2007-02-01 - 2007-02-01.
Poster

Misund, Kristine; Hoel, Sunniva; Bruland, Torunn; Anderssen, Endre; Lægreid, Astrid; Thommesen, Liv. (2007) Global gene expression in HEK 293 cells with controllable ICER I and IIg - overexpression. Norsk Biokjemisk Selskaps 43. kontaktmøte ; Lillehammer. 2007-02-01 - 2007-02-04.
Poster

Steigedal, Tonje Strømmen; Bruland, Torunn; Misund, Kristine; Thommesen, Liv; Lægreid, Astrid. (2007) Inducible cAMP early repressor (ICER) suppresses gastrin-mediated activation of cyclin D1 and c-fos gene expression. Norsk Biokjemisk Selskaps 43. kontaktmøte ; Lillehammer. 2007-02-01 - 2007-02-04.
Academic lecture

Steigedal, Tonje; Bruland, Torunn; Misund, Kristine; Thommesen, Liv; Lægreid, Astrid. (2007) Inducible cAMP early repressor (ICER) suppresses gastrin-mediated activation of cyclin D1 and c-fos gene expression. The Norwegian Bichemical Society 43. Contact Meeting . Norsk Biokjemisk Selskap; Lillehammer. 2007-02-01 - 2007-02-04.
Poster

Sæten, Christina; Misund, Kristine; Steigedal, Tonje Strømmen; Lægreid, Astrid; Thommesen, Liv; Bruland, Torunn. (2007) Complex functional studies in mammalian cells using transfected cell arrays. Norsk Biokjemisk Selskaps 43. kontaktmøte ; Lillehammer. 2007-02-01 - 2007-02-04.
Academic lecture

Sæten, Christina; Misund, Kristine; Steigedal, Tonje; Otterlei, Marit; Lægreid, Astrid; Thommesen, Liv; Bruland, Torunn. (2007) Complex functional studies in mammalian cells using transfected cell arrays. The Norwegian Bichemical Society 43. Contact Meeting . Norsk Biokjemisk Selskap (NBS); Lillehammer. 2007-02-01 - 2007-02-04.
Academic lecture

Yan Hua, Chen; Ramampiaro, Heri; Lægreid, Astrid; Sætre, Rune. (2007) ProtIR prototype: abstract relevance for Protein-Protein Interaction in BioCreAtIvE2 Challenge, PPI-IAS subtask. BioCreAtIvE II . CNIO; Madrid. 2007-04-23 - 2007-04-25.

2006

Poster

Arbo, Ingerid; Brattbakk, Hans-Richard; Lindberg, Fedon; Lægreid, Astrid; Langaas, Mette; Alsberg, Bjørn Kåre; Slørdahl, Stig Arild; Nilsson, Astrid; Langsrud, Øyvind; Kulseng, Bård Eirik; Johansen, Berit. (2006) Definisjon av en ”livsstilsalgoritme” til anvendelse for forebygging, diagnose og terapi ved kronisk sykdom. Regional forsknings- og utviklingskonferanse 2006 " Forskning – undring satt i system" . Helse Midt-Norge; Stjørdal. 2006-04-24 - 2006-04-25.
Poster

Bruland, Torunn; Anderssen, Endre; Eitrem, Berit Doseth; Bergum, Hallgeir; Beisvåg, Vidar; Lægreid, Astrid. (2006) Optimization of cDNA microarrays procdures using optimization criteria that does not rely on an external standard. Poster presentation ICSB-2006 Japan . The 7th International Conference on System Biology; Yokohama. 2006-10-09 - 2006-10-13.
Poster

Günther, Clara-Cecilie; Langaas, Mette; Lydersen, Stian; Beisvåg, Vidar; Junge, Frode Romstad Krohn; Bergum, Hallgeir; Lægreid, Astrid. (2006) Statistical hypothesis testing of association between two lists of genes. Statistics for gene and protein expression workshop . Chalmers; Gøteborg. 2006-05-09 - 2006-05-11.
Poster

Misund, Kristine; Hoel, Sunniva; Bruland, Torunn; Anderssen, Endre; Lægreid, Astrid; Thommesen, Liv. (2006) Global gene expression in HEK 293 cells with controllable ICER I or IIgamma overexpression. The Seventh International Conference on Systems Biology; ICSB 2006 ; 2006-10-08 - 2006-10-13.
Poster

Oestvang, Janne; Brattbakk, Hans-Richard; Huseby, Sjur; Langaas, Mette; Lægreid, Astrid; Johansen, Berit. (2006) Lysophosphatidylcholine stimulates increased level of transcript of proinflammatory genes in macrophages. The 7th International Conference on Systems Biology ; Yokohama. 2006-10-09 - 2006-10-13.
Poster

Oestvang, Janne; Brattbakk, Hans-Richard; Huseby, Sjur; Langaas, Mette; Lægreid, Astrid; Johansen, Berit. (2006) Transcription profiling show induction of a wide range of proinflammatory genes in response to lysophosphatidylcholine stimulation in monocytes. XIV International Symposium on Atherosclerosis ; Roma. 2006-06-18 - 2006-06-22.
Poster

Steigedal, Tonje S.; Bruland, Torunn; Eitrem, Berit Doseth; Endre, Anderssen; Thommesen, Liv; Lægreid, Astrid. (2006) Systems Biology of Gastrointestinal Tumour BiologyStudies of gastrin mediated regulation of gene expression. The 7th International Conference on Systems Biology ; Yokohama. 2006-10-09 - 2006-10-11.

2005

Academic lecture

Anderssen, Endre; Bruland, Torunn; Ween, Ola; Langaas, Mette; Follestad, Turid; Lægreid, Astrid. (2005) Design and analysisi of microarray time series experiment. NBS Kontaktmøte 2005 . NBS; Tromsø. 2005-01-13 - 2005-01-16.
Poster

Arbo, Ingerid; Lindberg, Fedon; Lægreid, Astrid; Langaas, Mette; Alsberg, Bjørn Kåre; Slørdahl, Stig Arild; Nilsson, Astrid; Johansen, Berit. (2005) Medical Technology in cardiovascular disease: The use, development and integration of microarray technology, statistics and computational biology on definition of a "Life style algorithm" to be employed in chronic disease prevention, diagnosis and therapy. European Science Foundation (ESF) Training Course, Microarray Gene Expression Analysis - Power and Potential of Standardisation . European Science Foundation; Trondheim. 2005-05-23 - 2005-05-27.
Poster

Arbo, Ingerid; Lindberg, Fedon; Lægreid, Astrid; Langaas, Mette; Alsberg, Bjørn Kåre; Slørdahl, Stig Arild; Nilsson, Astrid; Langsrud, Øyvind; Johansen, Berit. (2005) Definition of a "lifestyle algorithm" to be used in chronic disease prevention, diagnosis and therapy. 2nd ESF Functional Genomics Conference "Functional Genomics and Disease" . European Science Foundation; Oslo. 2005-09-06 - 2005-09-10.
Poster

Bruland, Torunn; Eitrem, Berit Doseth; Anderssen, Endre; Beisvåg, Vidar; Lægreid, Astrid. (2005) Effects of choice and dose of dT blockers in cDNA microarray experiments. NBS Contact meeting . NBS; Tromsø. 2005-01-19 - 2005-01-22.
Poster

Bruland, Torunn; Sæten, Christina; Strømmen, Tonje; Bergum, Hallgeir; Otterlei, Marit; Thommesen, Liv; Lægreid, Astrid. (2005) High-throughput characterisation of gene function using cell microarray. The2nd ESF Functional Genomic Conference, Oslo . ESF; Oslo. 2005-09-06 - 2005-09-10.
Poster

Gunther, Clara-Cecilie; Langaas, Mette; Lydersen, Stian; Beisvåg, Vidar; Jynge, Frode Romstad Krohn; Bergum, Hallgeir; Lægreid, Astrid. (2005) Statistical Hypothesis Testing of Association Between Two Reporter Lists Within the GO-hierarchy. European Meeting of Statisticians ; Oslo. 2005-07-23 - 2005-07-28.
Academic lecture

Kusnierczyk, Waclaw; Aamodt, Agnar; Lægreid, Astrid. (2005) Knowledge-Intensive Case-Based Support for Automated Explanation of Biological Phenomena. International Conference on Case Based Reasoning (ICCBR) ; Chicago, IL. 2005-08-23 - 2005-08-26.
Academic lecture

Lægreid, Astrid; Thommesen, Liv; Bruland, Torunn; Ween, Ola; Sandvik, Arne K.; Bergum, Hallgeir; Beisvåg, Vidar; Kusnierczyk, W; Aamodt, Agnar; Komorowski, Jan. (2005) System biology of the normal and diseased gastrointestinal system. 8th International meeting of microarray gene expression data society ; Bergen. 2005-09-11 - 2005-09-13.
Academic lecture

Misund, Kristine; Lægreid, Astrid; Thommesen, Liv. (2005) Constitutive and inducible expression of ICER in HEK 293. Kontaktmøtet Norsk Biokjemisk Selskap 2005 ; 2005-01-13 - 2005-01-16.
Academic lecture

Nørsett, Kristin; Bruland, Torunn; Ween, Ola; Hofsli, Eva; Thommesen, Liv; Misund, Kristine; Strømmen, Tonje; Kusnierczyk, Waclaw; Aamodt, Agnar; Midelfart, Herman; Hvidsten, Torgeir Rhoden; Langaas, Mette; Komorowski, Jan; Sandvik, Arne Kristian; Lægreid, Astrid. (2005) Systems biology of the normal and diseased gastrointestinal system. 2nd ESF Functional Genomics Conference ; 2005-01-10 - 2005-01-13.
Poster

Strømmen, Tonje; Ween, Ola; Thommesen, Liv; Lægreid, Astrid. (2005) Detection of alternatively spliced variants of ICER, a member of the CREB/CREM/ATF transcription factor family. NBS Winter meeting-january 2005-Tromsø ; 2005-01-15 - 2005-01-18.
Popular scientific lecture

Sætre, Rune; Tveit, Amund; Ranang, Martin Thorsen; Strømmen, Tonje; Thommesen, Liv; Stunes, Astrid Kamilla; Lægreid, Astrid. (2005) gProt: Annotating Protein Interactions Using Google and Gene Ontology. Knowledge-Based Intelligent Information and Engineering Systems: 9th International Conference, KES 2005 . Rajiv Khosla, Robert J. Howlett, Lakhmi C. Jain; Melbourne. 2005-09-14 - 2005-09-16.
Academic lecture

Sætre, Rune; Tveit, Amund; Strømmen, Tonje; Lægreid, Astrid. (2005) Semantic Annotation of Biomedical Literature Using Google. Data Mining and Bioinformatics Workshop (DMBIO 2005, In conjunction with ICCSA 2005) . The Institute of High Performance Computing (IHPC); Singapore. 2005-05-09 - 2005-05-12.
Academic lecture

Tveit, Amund; Sætre, Rune; Strømmen, Tonje; Lægreid, Astrid. (2005) ProtChew: Automatic Extraction of Protein Names from Biomedical Literature. International Workshop on Biomedical Data Engineering (BMDE 2005, In conjunction with ICDE 2005) . IEEE, Shunsuke UEMURA (NAIST); Tokyo. 2005-04-03 - 2005-04-04.
Academic lecture

Ween, Ola; Beisvåg, Vidar; Strømmen, Tonje; Lægreid, Astrid. (2005) Specific detection of alternative splice variants using oligonucleotide microarrays. 2nd ESF Functional Genomics Conference: Functional Genomics and Disease, Oslo 6-11 september 2005 ; 2005-11-06 - 2005-11-11.
Poster

Ween, Ola; Beisvåg, Vidar; Strømmen, Tonje; Lægreid, Astrid. (2005) Specific detection of alternative splice variants using oligonucleotide microarrays. 2nd ESF Functional Genomics Conference: Functional Genomics and Disease, Oslo 6-11 september 2005 ; 2005-11-06 - 2005-11-11.
Academic lecture

Bruland, Torunn; Bergum, Hallgeir; Ween, Ola; Thommesen, Liv; Lægreid, Astrid. (2005) System biology of the normal and diseased gastrointestinal system: High-througput characterisation of gene function using cell microarray. 2nd ESF Function genomica and disease ; Oslo. 2005-09-06 - 2005-09-10.
Poster

Misund, Kristine; Lægreid, Astrid; Thommesen, Liv. (2005) Constitutive and inducible expression of ICER in HEK 293. NBS kontaktmøte ; Tromsø. 2005-01-13 - 2005-01-16.
Academic lecture

Nørsett, K; Bruland, Torunn; Ween, Ola; Hofsli, Eva; Thommesen, Liv; Misund, Kristine; Strømmen, Tonje; Komorowski, Jan; Sandvik, Arne K.; Lægreid, Astrid. (2005) Systems biology of the normal and diseased gastrointestinal system. 2nd ESF Function genomics and disease ; Oslo. 2005-09-06 - 2005-09-10.
Poster

Steigedal, Tonje S.; Bruland, Torunn; Ween, Ola; Misund, Kristine; Thommesen, Liv; Lægreid, Astrid. (2005) Function of splice variants of the transcriptional repressor ICER in gastrin-mediated responses. The Norwegian Biochemical Society 41st Contact Meeting ; 2005-01-13 - 2005-01-16.
Poster

Steigedal, Tonje Strømmen; Bruland, Torunn; Ween, Ola; Misund, Kristine; Thommesen, Liv; Lægreid, Astrid. (2005) Function of splice variants of the transcriptional repressor ICER in gastrin-mediated reponses. NBS kontaktmøte ; Tromsø. 2005-01-13 - 2005-01-16.

2004

Academic lecture

Bruland, Torunn; Bergum, Hallgeir; Steigedal, Tonje; Otterlei, Marit; Thommesen, Liv; Lægreid, Astrid. (2004) Array based screening og gene function and cell-biological application of transfected-cell microarrays. NBS Kontaktmøte . NBS; Hafjell. 2004-01-15 - 2004-01-18.
Academic lecture

Drabløs, Finn; Hammer, Mikael; Lægreid, Astrid; Hauglid, Jon Olav; Alsberg, Bjørn Kåre. (2004) Bioinformatics. InfoSam2020 . NTNU; Trondheim. 2004-04-19 - 2004-04-20.
Poster

Kusnierczyk, Waclaw; Aamodt, Agnar; Lægreid, Astrid. (2004) Towards Automated Explanation of Gene-Gene Relationships. RECOMB 2004 ; 2004-03-27 - 2004-04-01.
Poster

Misund, Kristine; Stunes, Astrid Kamilla; Tømmerdal, Linda; Thommesen, Liv; Bruland, Torunn; Lægreid, Astrid. (2004) Constitutive expression of ICER in the cell-line HEK 293. Kontaktmøtet Norsk Biokjemisk Selskap 2004 ; 2004-01-15 - 2004-01-18.
Academic lecture

Ween, Ola; Lægreid, Astrid. (2004) Specific detection of alternative splice variants using oligonucleotide microarrays. NBS kontakmøte 2004 . NBS; Hafjell Lillehamer. 2004-01-15 - 2004-01-18.
Poster

Ween, Ola; Lægreid, Astrid. (2004) Specific detection of alternative splice variants using oligonucleotide microarrays. Symposium - Alternate Transcript Diversity – Data, Biology, and Therapeutics; Wellcome Trust Genome Campus, Hinxton, UK ; 2004-11-22 - 2005-11-23.
Poster

Strømmen, Tonje; Prestvik, Wenche Slettahjell; Wong, Garry; Thommesen, Liv; Lægreid, Astrid. (2004) Detection and functional studies of alternatively spliced variants of ICER, a member of the CREB/CREM/ATF transcription factor family. Kontaktmøtet Norsk Biokjemisk Selskap ; Lillehammer. 2004-01-15 - 2004-01-18.

2003

Poster

Hofsli, Eva; Sandvik, Arne K.; Langaas, Mette; Lægreid, Astrid; Thommesen, Liv. (2003) Identification of gastrin-regulated genes in human carcinoid tumor cells. Functional genomics and diseases ; Praha, Tjekkia. 2003-05-14 - 2003-05-17.
Poster

Hofsli, Eva; Sandvik, Arne Kristian; Langaas, Mette; Lægreid, Astrid. (2003) Identification of gastrin-regulated genes in human carcinoid tumor cells. Functional genomics and diseases . [Mangler data]; Praha, Tjekkia. 2003-05-17.
Academic lecture

Nørsett, Kristin; Kuznierczyk, W.; Lægreid, Astrid; Langaas, M.; Waldum, Helge; Sandvik, Arne Kristian. (2003) Gene expression profiles in gastric mucosa during therapeutic acid inhibition. ESF, Functional Genomics and Disease. 1st Conference . [Mangler data]; Prague. 2003-05-17.
Academic lecture

Nørsett, Kristin; Kuznierczyk, W.; Lægreid, Astrid; Langaas, M.; Yadetie, Fekadu; Kvam, S.N.; Wørlund, S.; Waldum, Helge; Sandvik, Arne Kristian. (2003) Gene expression profiles in hypergastrinemic rats and patients. Norsk Biokjemisk Selskaps Årsmøte . [Mangler data]; Norge. 2003-01-23.
Academic lecture

Thommesen, Liv; Bergum, Hallgeir; Langaas, Mette; Beisvåg, Vidar; Sandvik, Arne K.; Bruland, Torunn; Ween, Ola; Lægreid, Astrid. (2003) Rat Microarray Analysis Resources. Meetings on rat genomics and Models ; Cold Spring Harbor Laboratory, NY. 2003-12-11 - 2003-12-14.
Academic lecture

Thommesen, Liv; Bergum, Hallgeir; Langaas, Mette; Beisvåg, Vidar; Sandvik, Arne Kristian; Bruland, Torunn; Ween, Ola; Lægreid, Astrid. (2003) Rat Microarray Analysis Resources. Meetings on rat genomics and Models . [Mangler data]; Cold Spring Harbor Laboratory, NY. 2003-12-14.
Poster

Thommesen, Liv; Lægreid, Astrid; Misund, Kristine. (2003) Constitutive expression of ICER in the human cell line AR42J. Kontaktmøtet Norsk Biokjemisk Selskap . [Mangler data]; Geilo. 2003-01-26.
Academic lecture

Witsø, Eivind; Beisvåg, Vidar; Langaas, M.; Lysvand, Hilde; Persen, Leif; Lægreid, Astrid; Bergh, Kåre. (2003) DNA microarray: A new diagnostic tool in orthopaedic infections?. 22nd Annual Meeting: European Bone and Joint Infection Society . [Mangler data]; Trondheim. 2003-05-10.
Poster

Thommesen, Liv; Lægreid, Astrid; Misund, Kristine. (2003) Constitutive expression of ICER in the human cell line AR42J. Kontaktmøtet Norsk Biokjemisk Selskap ; Geilo. 2003-01-23 - 2003-01-26.

2002

Poster

Beisvåg, Vidar; Jølsum, Lars; Kusnierczyk, Waclaw; Langaas, Mette; Alsberg, Bjørn Kåre; Bergum, Hallgeir; Komorowski, Jan; Sandvik, Arne Kristian; Lægreid, Astrid. (2002) eGOn � a new tool for mapping microarray data onto the Gene Ontology structure. Standards and Ontologies for Functional Genomics . EBI; Hinxton. 2002-11-17 - 2002-11-20.
Poster

Midelfart, Herman; Kusnierczyk, Waclaw Marcin; Hvidsten, Torgeir Rhoden; Lægreid, Astrid; Komorowski, Jan. (2002) Learning Yeast Gene Function from Expression Programs and Gene Ontology. Norwegian Biochemical Society’s Wintermeeting ; 2002-01-17 - 2002-01-20.
Popular scientific lecture

Nørsett, Kristin; Lægreid, Astrid; Yadetie, Fekadu; Midelfart, H; Komorowski, Jan; Falkmer, Sture Emil; Grønbech, Jon Erik; Waldum, Helge; Sandvik, Arne Kristian. (2002) Molekylær klassifisering av magekreft. Norsk Gastroenterologisk Forenings 29. årsmøte . [Mangler data]; Lillehammer. 2002-02-10.
Popular scientific lecture

Yadetie, Fekadu; Bakke, Ingunn; Lægreid, Astrid; Kusnierczyk, Waclaw; Komorowski, Jan; Waldum, Helge; Sandvik, Arne Kristian. (2002) Analysis of effects of the PPAR alpha agonist ciprofibrate on rat hepatic gene expressions using cDNA microarrays. The 7th IUBMB Conference Receptor-ligand Interactions Molecular, Physiological and Pharmacological Aspects ; Bergen. 2002-05-08.

2001

Poster

Hvidsten, Torgeir Rhoden; Komorowski, Jan; Sandvik, AK; Lægreid, Astrid. (2001) Predicting gene function from gene expressions and ontologies. Pacific Symposium on Biocomputiong, PSB2001 . [Mangler data]; Mauna Lani, Hawaii, USA, 3-7 January.
Academic lecture

Hvidsten, TR; Sandvik, Arne Kristian; Midelfart, Herman; Lægreid, Astrid; Komorowski, Jan. (2001) A method based on rough set supervised learning used to predict the biological function of unknown genes from DNA microarray gene expression data. Third International Meeting on Microarray Data Standards, Annnotations,Ontologies and Databases. . [Mangler data]; Stanford University, Palo Alto, CA.. 2001-03-30.
Academic lecture

Midelfart, Herman; Lægreid, Astrid; Komorowski, Jan. (2001) Classification of Gene Expression Data in an Ontology. The second international Symposium on Medical Data Analysis (ISMDA-2001) . [Mangler data]; Madrid, Spania. 2001-10-09.

2000

Poster

Hvidsten, Torgeir Rhoden; Jenssen, Tor-Kristian; Komorowski, Jan; Lægreid, Astrid; Sandvik, AK; Tjeldvoll, Dyre. (2000) Template-based gene expression analysis. The Fourth Annual International Conference on Computational Molecular Biology . [Mangler data]; Tokyo, Japan, April 8-11.
Poster

Jenssen, Tor-Kristian; Komorowski, Jan; Lægreid, Astrid; Hovig, Eivind. (2000) Pubgen: Discovering and visualising gene-gene relations. The Fourth Annual International Conference on Computational Molecular Biology . [Mangler data]; Tokyo, 8-11 april 2000..
Academic lecture

Komorowski, Jan; Hvidsten, Torgeir Rhoden; Jenssen, Tor-Kristian; Tjeldvoll, Dyre; Hovig, Eivind; Sandvik, AK; Lægreid, Astrid. (2000) Towards Knowledge Discovery from cDNA Microarray Gene Expression Data. Principles of data mining and knowledge discovery : 4th European conference . [Mangler data]; Lyon, France, September 13 - 16.

1999

Poster

Hvidsten, Torgeir Rhoden; Jenssen, Tor-Kristian; Lægreid, Astrid; Øhrn, Aleksander; Tjeldvoll, Dyre; Komorowski, Jan. (1999) Boolean Reasoning in the Analysis of Gene Expression Data. Data Mining for Bioinformatics: Towards in Silico Biology . [Mangler data]; Cambridge, UK, November 10-12.
Popular scientific lecture

Jenssen, TK; Lægreid, Astrid; Komorowski, Jan. (1999) Knowledge-Based Data Mining in Genomics. Data Mining for Bioinformatics - Towards In Silico Biology . [Mangler data]; Cambridge, UK, 1999.
Popular scientific lecture

Nørsett, Kristin; Thommesen, Liv; Hofsli, E; Sandvik, AK; Lægreid, Astrid. (1999) Molecular characterization of the neuroendicrine cell line AR42J. Biokjemisk kontaktmøte . [Mangler data]; Tromsø 1999.

1998

Academic lecture

Johansen, Berit; Lægreid, Astrid; Sjursen, Wenche; Thommesen, Liv; Anthonsen, Marit Walbye. (1998) A role for both secretory and cytosolic phospholipase A2 in TNF mediated nuclear translocation of NFkB and ICAM expression in keratinocytes?. NBS Kontaktmøte 98 . [Mangler data]; Lillehammer, Norge.
Popular scientific lecture

Johansen, Berit; Lægreid, Astrid; Sjursen, Wenche; Thommesen, Liv; Anthonsen, Marit Walbye. (1998) A role of both secretory and cytosolic phospholipase A2 in TNF mediated nuclear translocation of NFkB and ICAM expression in keratinocytes?. NBS Kontaktmøte 98 . [Mangler data]; Lillehammer, Norge.
Poster

Nørsett, Kristin; Thommesen, Liv; Hofsli, E; Sandvik, AK; Lægreid, Astrid. (1998) Molecular characterization of the neuroendocrine cell line AR42J. Norsk Biokjemisk Selskaps Årsmøte . [Mangler data]; [Mangler data].
Poster

Thommesen, Liv; Nørsett, Kristin; Sandvik, AK; Lægreid, Astrid. (1998) ICER expression in gastrin stimulated endocrine cells. Norsk Biokjemisk Selskaps Årsmøte . [Mangler data]; [Mangler data].
Poster

Thommesen, Liv; Nørsett, Kristin; Sandvik, AK; Lægreid, Astrid. (1998) Induction of ICER gene expression in neuroendocrine derived cell lines. International Congress on Signal Transduction . [Mangler data]; Jerusalem.

1997

Academic lecture

Johansen, Berit; Lægreid, Astrid; Sjursen, Wenche; Thommesen, Liv. (1997) A role for both secretory and cytosolic phospholipase A2 in TNF mediated nuclear translocation of NFkB and ICAM expression in keratinocytes. FEBS Special Meetintg on Signal Transduction . [Mangler data]; Amsterdam, Nederland.
Academic lecture

Sandvik, AK; Gabestad, K.; Thommesen, Liv; Lægreid, Astrid. (1997) Mechanisms for transcriptional regulation of the immediate early response gene ICER vary between different neuroendocrine derived cell lines. XXXIII International Congress of Physiological Sciences . [Mangler data]; St. Petersburg.

1996

Programme participation

Lægreid, Astrid. (1996) ... Kloning av sau ... Schrødingers katt, NRK [TV]. null.
Academic lecture

Lægreid, Astrid; Nonstad, Unni; Sundan, Anders; Espevik, Terje. (1996) Lipopolysaccharide signalling mechanism in human adenocarcinoma SW480 cells. 32. Biokjemiske kontaktmøte . [Mangler data]; Geilo.
Academic lecture

Thommesen, Liv; Sjursen, Wenche; Gåsvik, Katrine; Johansen, Berit; Lægreid, Astrid. (1996) The role of phospholipases A2 in the activation of NFkB in human keratinocytes. 32. Biokjemiske kontaktmøte . [Mangler data]; Geilo.

Språkvelger

Astrid Lægreid

Astrid Lægreid

About

Publications

2023

2022

2021

2020

2019

2017

2016

2015

2014

2013

2012

2010

2009

2008

2007

2006

2005

2004

2003

2002

2001

2000

1998

1996

1994

Journal publications

Part of book/report

INFORMASJONSMATR

Teaching

Courses

Media

2018

2017

2016

2014

2013

2012

2011

2010

2009

2008

2007

2006

2005

2004

2003

2002

2001

2000

1999

1998

1997

1996