2026

• Øvrehus, Marius Altern; Kristiansen, Kåre Andre; Langlo, Knut Asbjørn Rise; Garimella, Pranav S.; Ix, Joachim H.; Shlipak, Michael G.; Bruheim, Per; Hallan, Stein Ivar. (2026) Reference intervals for kidney tubular secretion markers in the general population: The HUNT3 study. Annals of Clinical Biochemistry
  Academic article
• Gezer, Mensure Elvan; Ayoubi, Layla; Bruheim, Per; Schwab, Clarissa. (2026) Deoxyhexose metabolism of food-related Lactobacillaceae and identification of a distinctive 1,2-propanediol utilization pathway in Liquorilactobacillus ghanensis DSM 18630. Food Microbiology
  Academic article
• Rane, Divyata Vilas; Haaland, Karen Lund; Refsnes, Åse; Skuggedal, Hege; Øverbø, Stinus Reklev; Bruheim, Per; García-Calvo, Laura. (2026) Escherichia coli BL21 adapts its central carbon metabolism to recombinant protein production and oxygen limitation. Microbial Cell Factories
  Academic article

2025

• Bergum, Olaug Elisabeth Torheim; Otterlei, Marit; Bruheim, Per. (2025) Multi-omics analysis of bacterial stress responses to identify antibiotic mode of action. Norges teknisk-naturvitenskapelige universitet
  Doctoral thesis
• Singleton, Amanda; Bergum, Olaug Elisabeth Torheim; Scheffold, Jana; Ræder, Synnøve Brandt; Thorfinnsdottir, Lilja Brekke; Røst, Lisa M.; Søgaard, Caroline Krogh; Bruheim, Per; Otterlei, Marit. (2025) A dual-mechanism antimicrobial peptide with antimutagenic activity targets the replisome and induces cell envelope stress. mSphere
  Academic article
• Simonsen, Signe; Larsen, Fia B.; Søgaard, Caroline Krogh; Jonsson, Nicolas; Lindorff-Larsen, Kresten; Bruheim, Per; Otterlei, Marit; Hartmann-Petersen, Rasmus; Kragelund, Birthe B.. (2025) Extreme multivalency and a composite short linear motif facilitate PCNA-binding, localisation and abundance of p21 (CDKN1A). The FEBS Journal
  Academic article

2024

• Gunnes, Sondre; Bruheim, Per. (2024) Performance of Saccharomyces cerevisiae and Kluyveromyces marxianus, Investigating the Impact of Carbon and Nitrogen Sources on Fermentation Characteristics. Norges teknisk-naturvitenskapelige universitet
  Master thesis
• Olaisen, Camilla; Røst, Lisa M.; Sharma, Animesh; Søgaard, Caroline Krogh; Khong, Tiffany; Berg, Sigrid Ravn; Jang, Mi; Nedal, Aina; Spencer, Andrew; Bruheim, Per. (2024) Multiple Myeloma Cells with Increased Proteasomal and ER Stress Are Hypersensitive to ATX-101, an Experimental Peptide Drug Targeting PCNA. Cancers
  Academic article
• Melbye, Kristin Soleim; Bruheim, Per. (2024) Production of Single Cell Protein from Kluyveromyces marxianus Utilising Whey and Fish Hydrolysate as Substrates. Norges teknisk-naturvitenskapelige universitet
  Master thesis
• Juell, Mathilde Fredrikke Haneborg; Bruheim, Per. (2024) Exploring the sustainable docosahexaenoic acid production in Auraontiochytrium limacinum SR21 using residual raw materials. NTNU
  Master thesis
• Haaland, Karen Lund; Bruheim, Per. (2024) The Effect of High Plasmid Copy Number and Oxygen Limitation on Growth and mCherry Production in Escherichia coli BL21 A3-mCherry. Norges teknisk-naturvitenskapelige universitet
  Master thesis
• Nedreås, Pia Moe-Nilssen; Bruheim, Per. (2024) Optimization of chicken hydrolysate as a nitrogen source for Fusarium venenatum in submerged culture. Norges teknisk-naturvitenskapelige universitet
  Master thesis
• Mjølnerød, Kristine; Bruheim, Per. (2024) Kluyveromyces marxianus Single-Cell Protein production from Salmon Hydrolysate and Whey. NTNU
  Master thesis
• Tellsgård, Sunniva Christiansen; Bruheim, Per. (2024) Research on Neurospora crassa cultivation using residual raw materials from the fish and poultry industry as organic nitrogen sources. Norges teknisk-naturvitenskapelige universitet
  Master thesis
• Rane, Divyata Vilas; Garcia Calvo, Laura; Kristiansen, Kåre Andre; Bruheim, Per. (2024) Zic-HILIC MS/MS Method for NADomics Provides Novel Insights into Redox Homeostasis in Escherichia coli BL21 Under Microaerobic and Anaerobic Conditions. Metabolites
  Academic article
• Bergum, Olaug Elisabeth Torheim; Singleton, Amanda Holstad; Røst, Lisa Marie Ivarsdatter; Bodein, Antoine; Scott-Boyer, Marie-Pier; Rye, Morten Beck; Droit, Arnaud; Bruheim, Per; Otterlei, Marit. (2024) SOS genes are rapidly induced while translesion synthesis polymerase activity is temporally regulated. Frontiers in Microbiology
  Academic article

2023

• Hallan, Stein Ivar; Øvrehus, Marius Altern; Darshi, Manjula; Montemayor, Daniel; Langlo, Knut Asbjørn Rise; Bruheim, Per; Sharma, Kumar. (2023) Metabolic Differences in Diabetic Kidney Disease Patients with Normoalbuminuria versus Moderately Increased Albuminuria. Kidney360
  Academic article
• Refsnes, Åse; Bruheim, Per. (2023) Analysis of The Consequences of Oxygen Limitation on the Redox Balance and Overflow Metabolites in Escherichia coli BL21 During Recombinant Protein Production. Norges teknisk-naturvitenskapelige universitet
  Master thesis
• Øvrebø, Stinus Reklev; Bruheim, Per. (2023) The effect of oxygen limitation on growth characteristics and the redox state of Escherichia coli BL21 during recombinant protein production. NTNU
  Master thesis
• Dankel, Simon Nitter; Kalleklev, Tine-Lise; Lunde, Siri; Stafsnes, Marit Hallvardsdotter; Bruheim, Per; Aloysius, Thomas Aquinas; Lindquist, Carine; SKORVE, JON; Nygård, Ottar Kjell; Madsen, Lise. (2023) Changes in Plasma Pyruvate and TCA Cycle Metabolites upon Increased Hepatic Fatty Acid Oxidation and Ketogenesis in Male Wistar Rats. International Journal of Molecular Sciences
  Academic article
• Singleton, Amanda Holstad; Bergum, Olaug Elisabeth Torheim; Søgaard, Caroline Krogh; Røst, Lisa M.; Olsen, Cecilie Elisabeth; Blindheim, Fredrik Heen; Ræder, Synnøve Brandt; Bjørnstad, Frithjof Andreas; Sundby, Eirik; Hoff, Bård Helge. (2023) Activation of multiple stress responses in Staphylococcus aureus substantially lowers the minimal inhibitory concentration when combining two novel antibiotic drug candidates. Frontiers in Microbiology
  Academic article
• Garcia Calvo, Laura; Rane, Divyata Vilas; Everson, Nikalet; Humlebrekk, Sigurd Tømmerberg; Mathiassen, Lise Femanger; Mæhlum, Astfrid Helene Morka; Malmo, Jostein; Bruheim, Per. (2023) Central carbon metabolite profiling reveals vector-associated differences in the recombinant protein production host Escherichia coli BL21. Frontiers in Chemical Engineering
  Academic article
• Scheffold, Jana; Bruheim, Per; Kjesbu, Joachim Sebastian; Jang, Mi. (2023) Serum-free alginate-C2C12 cells microcapsule as a model of alternative animal protein source. Frontiers in Nutrition
  Academic article
• Thorfinnsdottir, Lilja Brekke; Garcia Calvo, Laura; Hovde Bø, Gaute; Bruheim, Per; Røst, Lisa Marie Ivarsdatter. (2023) Optimized Fast Filtration-based Sampling and Extraction Enables Precise and Absolute Quantification of the Escherichia coli Central Carbon Metabolome. Metabolites
  Academic article
• Eide, Marta; Goksøyr, Anders; Yadetie, Fekadu; Gilabert, Alejandra; Bartosova, Zdenka; Frøysa, Håvard Guldbrandsen; Fallahi, Shirin; Zhang, Xiaokang; Blaser, Nello; Jonassen, Inge. (2023) Integrative omics-analysis of lipid metabolism regulation by peroxisome proliferator-activated receptor a and b agonists in male Atlantic cod. Frontiers in Physiology
  Academic article
• Rau, E-Ming; Aasen, Inga Marie; Bartosova, Zdenka; Bruheim, Per; Ertesvåg, Helga. (2023) Utilizing lipidomics and fatty acid synthase inhibitors to explore lipid accumulation in two thraustochytrid species. Algal Research
  Academic article
• Jaramillo-Jiménez, Alberto; Melvær, Giil Lasse; Borda, Miguel Germán; Tovar-Rios, Diego Alejandro; Kristiansen, Kåre Andre; Bruheim, Per; Aarsland, Dag; Barreto, George E.; Berge, Rolf Kristian. (2023) Serum TCA cycle metabolites in Lewy bodies dementia and Alzheimer's disease: Network analysis and cognitive prognosis. Mitochondrion (Amsterdam. Print)
  Academic article
• Thorfinnsdottir, Lilja Brekke; Hovde Bø, Gaute; Booth, James Alexander; Bruheim, Per. (2023) Survival of Escherichia coli after high-antibiotic stress is dependent on both the pregrown physiological state and incubation conditions. Frontiers in Microbiology
  Academic article

2022

• Rau, E-Ming; Bartosova, Zdenka; Kristiansen, Kåre Andre; Aasen, Inga Marie; Bruheim, Per; Ertesvåg, Helga. (2022) Overexpression of two new acyl-CoA:diacylglycerol acyltransferase 2-like acyl-CoA:sterol acyltransferases enhanced squalene accumulation in Aurantiochytrium limacinum. Frontiers in Microbiology
  Academic article
• Jang, Mi; Scheffold, Jana; Bruheim, Per. (2022) Isolation and cultivation of primary muscle cells from Lobster (Homarus gammarus). In vitro Cellular & Developmental Biology-Animal
  Academic article
• Carracedo Huroz, Sergio; Lirussi, Lisa; Alsøe, Lene; Segers, Filip; Wang, Changliang; Bartosova, Zdenka; Bohov, Pavol; Tekin, Nuriye Basdag; Kong, Xiang Yi; Esbensen, Qin Ying. (2022) SMUG1 regulates fat homeostasis leading to a fatty liver phenotype in mice. DNA Repair
  Academic article
• Røst, Lisa M.; Ræder, Synnøve Brandt; Olaisen, Camilla; Søgaard, Caroline Krogh; Sharma, Animesh; Bruheim, Per; Otterlei, Marit. (2022) PCNA regulates primary metabolism by scaffolding metabolic enzymes. Oncogene
  Academic article
• Jang, Mi; Scheffold, Jana; Røst, Lisa M.; Cheon, Hyejeong; Bruheim, Per. (2022) Serum-free cultures of C2C12 cells show different muscle phenotypes which can be estimated by metabolic profiling. Scientific Reports
  Academic article
• Kumar, Kanhaiya; Bruheim, Per. (2022) Nutrient-depended metabolic switching during batch cultivation of Streptomyces coelicolor explored with absolute quantitative mass spectrometry based metabolite profiling. 3 Biotech
  Academic article
• Simensen, Vetle; Schulz, Christian; Karlsen, Emil; Bråtelund, Signe; Burgos, Idun Maria Tokvam; Thorfinnsdottir, Lilja Brekke; Garcia Calvo, Laura; Bruheim, Per; Almaas, Eivind. (2022) Experimental determination of Escherichia coli biomass composition for constraint-based metabolic modeling. PLOS ONE
  Academic article
• Kumar, Kanhaiya; Bruheim, Per. (2022) A comparative study at bioprocess and metabolite levels of superhost strain Streptomyces coelicolor M1152 and its derivative M1581 heterologously expressing chloramphenicol biosynthetic gene cluster. Biotechnology and Bioengineering
  Academic article
• Jang, Mi; Pete, Ellen Sofie; Bruheim, Per. (2022) The impact of serum-free culture on HEK293 cells: From the establishment of suspension and adherent serum-free adaptation cultures to the investigation of growth and metabolic profiles. Frontiers in Bioengineering and Biotechnology
  Academic article
• Røst, Lisa M.; Louet, Claire; Bruheim, Per; Flo, Trude Helen; Gidon, Alexandre. (2022) Pyruvate Supports RET-Dependent Mitochondrial ROS Production to Control Mycobacterium avium Infection in Human Primary Macrophages. Frontiers in Immunology
  Academic article
• Olsen, Cecilie Elisabeth; Blindheim, Fredrik Heen; Søgaard, Caroline Krogh; Røst, Lisa M.; Singleton, Amanda; Bergum, Olaug Elisabeth Torheim; Bruheim, Per; Otterlei, Marit; Sundby, Eirik; Hoff, Bård Helge. (2022) Halogenated Pyrrolopyrimidines with Low MIC on Staphylococcus aureus and Synergistic Effects with an Antimicrobial Peptide. Antibiotics
  Academic article

2021

• Gidon, Alexandre; Louet, Claire; Røst, Lisa M.; Bruheim, Per; Flo, Trude Helen. (2021) The Tumor Necrosis Factor Alpha and Interleukin 6 Auto-paracrine Signaling Loop Controls Mycobacterium avium Infection via Induction of IRF1/IRG1 in Human Primary Macrophages. mBio
  Academic article
• Fuchino, Katsuya; Chan, Helena; Hwang, Ling Chin; Bruheim, Per. (2021) The Ethanologenic bacterium Zymomonas mobilis divides asymmetrically and exhibits heterogeneity in DNA content. Applied and Environmental Microbiology
  Academic article
• Kumar, Kanhaiya; Bruheim, Per. (2021) Large dependency of intracellular NAD and CoA pools on cultivation conditions in Saccharomyces cerevisiae. BMC Research Notes
  Academic article
• Nilsen, Mona Synnøve; Lindquist, Carine; Stafsnes, Marit Hallvardsdotter; Bjørndal, Bodil; Bruheim, Per; Aloysius, Thomas Aquinas; Nygård, Ottar; SKORVE, Jon; Madsen, Lise; Dankel, Simon E Nitter. (2021) Plasma 3-hydroxyisobutyrate (3-HIB) and methylmalonic acid (MMA) are markers of hepatic mitochondrial fatty acid oxidation in male Wistar rats. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
  Academic article
• Skedsmo, Fredrik; Espenes, Arild; Tranulis, Michael A.; Matiasek, Kaspar; Gunnes, Gjermund; Bjerkås, Inge; Moe, Lars; Røed, Susan Skogtvedt; Berendt, Mette; Fredholm, Merete. (2021) Impaired NDRG1 functions in Schwann cells cause demyelinating neuropathy in a dog model of Charcot-Marie-Tooth type 4D. Neuromuscular Disorders
  Academic article
• Jin, Yang; Harvey, Thomas Nelson; Bartosova, Zdenka; Hassani, Sahar; Bruheim, Per; Sandve, Simen Rød; Vik, Jon Olav. (2021) Diet and Life Stage-Associated Lipidome Remodeling in Atlantic Salmon. Journal of Agricultural and Food Chemistry
  Academic article
• Rutkis, Reinis; Strazdina, Inese; Lasa, Zane; Bruheim, Per; Kalnenieks, Uldis. (2021) Ethanologenesis and respiration in a pyruvate decarboxylase-deficient Zymomonas mobilis. BMC Research Notes
  Academic article
• Abdollahi, Pegah; Vandsemb, Esten; Elsaadi, Samah; Røst, Lisa Marie; Yang, Rui; Hjort, Magnus Aassved; Andreassen, Trygve; Misund, Kristine; Slørdahl, Tobias Schmidt; Rø, Torstein Baade. (2021) Phosphatase of Regenerating Liver-3 Regulates Cancer Cell Metabolism in Multiple Myeloma. The FASEB Journal
  Academic article
• Sumabe, Balagra Kasim; Ræder, Synnøve Brandt; Røst, Lisa M.; Sharma, Animesh; Donkor, Eric S.; Mosi, Lydia; Duodu, Samuel; Bruheim, Per; Otterlei, Marit. (2021) Nucleoside Analogues Are Potent Inducers of Pol V-mediated Mutagenesis. Biomolecules
  Academic article
• Pedersen, Eilif; Eitungjerde, Sara; André, Thea Harnes; Bruheim, Per; Grønflaten, Lars Trovatten; Gundersen, Ingeborg Nævdal; Hartnik, Lukas; Kraemer, Frank Alexander; Sigurjónsson, Jóhannes B.; Torvatn, Tim Kristian Andreas. (2021) Fremtidens teknologistudier (FTS), grupperapport: A3 - 5-årig master. NTNU
  Research report
• Bartosova, Zdenka; Villa Gonzalez, Susana; Voigt, Andre; Bruheim, Per. (2021) High throughput semi-quantitative UHPSFC-MS/MS lipid profiling and lipid class determination. Journal of Chromatographic Science
  Academic article
• Kumar, Kanhaiya; Venkatraman, Vishwesh; Bruheim, Per. (2021) Adaptation of central metabolite pools to variations in growth rate and cultivation conditions in Saccharomyces cerevisiae. Microbial Cell Factories
  Academic article
• Bartosova, Zdenka; Ertesvåg, Helga; Nyfløt, Eirin Lishaugen; Kämpe, Kristoffer; Aasen, Inga Marie; Bruheim, Per. (2021) Combined Metabolome and Lipidome analyses for in-depth characterization of lipid accumulation in the DHA producing Aurantiochytrium sp. T66. Metabolites
  Academic article

2020

• Røst, Lisa Marie; Otterlei, Marit; Bruheim, Per. (2020) Targeted Mass Spectrometric Metabolite Profiling for Studies of Central Carbon Metabolism. Norges teknisk-naturvitenskapelige universitet
  Doctoral thesis
• Røst, Lisa Marie; Thorfinnsdottir, Lilja Brekke; Kumar, Kanhaiya; Fuchino, Katsuya; Langørgen, Ida Eide; Bartosova, Zdenka; Kristiansen, Kåre Andre; Bruheim, Per. (2020) Absolute Quantification of the Central Carbon Metabolome in Eight Commonly Applied Prokaryotic and Eukaryotic Model Systems. Metabolites
  Academic article
• Fontana, Diletta; Mauri, Mario; Renso, Rossella; Docci, Mattia; Crespiatico, Ilaria; Røst, Lisa Marie; Jang, Mi; Niro, Antonio; D’Aliberti, Deborah; Massimino, Luca. (2020) ETNK1 mutations induce a mutator phenotype that can be reverted with phosphoethanolamine. Nature Communications
  Academic article
• Røst, Lisa Marie; Darestani, Armaghan Shafaei; Fuchino, Katsuya; Bruheim, Per. (2020) Zwitterionic HILIC tandem mass spectrometry with isotope dilution for rapid, sensitive and robust quantification of pyridine nucleotides in biological extracts. Journal of chromatography. B
  Academic article
• Fuchino, Katsuya; Kalnenieks, Uldis; Rutkis, Reinis; Grube, Mara; Bruheim, Per. (2020) Metabolic Profiling of Glucose-Fed Metabolically Active Resting Zymomonas mobilis Strains. Metabolites
  Academic article
• Fuchino, Katsuya; Bruheim, Per. (2020) An assessment of serial co-cultivation approach for generating novel Zymomonas mobilis strains. BMC Research Notes
  Academic article
• Fuchino, Katsuya; Bruheim, Per. (2020) Increased salt tolerance in Zymomonas mobilis strain generated by adaptative evolution. Microbial Cell Factories
  Academic article

2019

• Skedsmo, Fredrik Strebel; Malachin, Giulia; Våge, Dag Inge; Hammervold, Mie Marie; Salvesen, Øyvind; Ersdal, Cecilie; Ranheim, Birgit; Stafsnes, Marit Hallvardsdotter; Bartosova, Zdenka; Bruheim, Per. (2019) Demyelinating polyneuropathy in goats lacking prion protein. The FASEB Journal
  Academic article
• Navarro, Miguel Octavio Perez; Simionato, Ane Stefano; Perez, Juan Carlos Bedoya; Barazetti, Andre Riedi; Emiliano, Janaina; Niekawa, Erika Tyemi Goya; Andreata, Matheus Felipe de Lima; Modolon, Fluvio; Dealis, Mickely Liuti; Araujo, Eduardo Jose de Almeida. (2019) Fluopsin C for treating multidrug-resistant infections: In vitro activity aganist clinically important strains and in vivo efficacy against carbapenemase-producing Klebsiella pneumoniae. Frontiers in Microbiology
  Academic article
• Volkova, Yulia A.; Averina, Elena B.; Vasilenko, Dmitry A; Sedenkova, Kseniya N; Grishin, Yuri K.; Bruheim, Per; Kuznetsova, Tamara S.; Zefirov, Nikolai S.. (2019) Unexpected Heterocyclization of Electrophilic Alkenes by Tetranitromethane in the Presence of Triethylamine. Synthesis of 5-Nitroisoxazoles. Journal of Organic Chemistry
  Academic article
• Øvrehus, Marius Altern; Bruheim, Per; Ju, Wenjun; Zelnick, Leila R.; Langlo, Knut Asbjørn Rise; Sharma, Kumar; Boer, Ian H. de; Hallan, Stein. (2019) Gene expression studies and targeted metabolomics reveal disturbed serine, methionine, and tyrosine metabolism in early hypertensive nephrosclerosis. Kidney International Reports
  Academic article
• Kalnenieks, Uldis; Balodite, Elina; Strahler, Steffi; Strazdina, Inese; Rex, Julia; Pentjuss, Agris; Fuchino, Katsuya; Bruheim, Per; Rutkis, Reinis; Pappas, Katherine M.. (2019) Improvement of acetaldehyde production in Zymomonas mobilis by engineering of its aerobic metabolism. Frontiers in Microbiology
  Academic article

2018

• Petrovic, Voin; Nepal, Anala; Olaisen, Camilla; Bachke, Siri; Hira, Jonathan; Søgaard, Caroline Krogh; Røst, Lisa Marie; Misund, Kristine; Andreassen, Trygve; Melø, Torun Margareta. (2018) Anti-Cancer Potential of Homemade Fresh Garlic Extract Is Related to Increased Endoplasmic Reticulum Stress. Nutrients
  Academic article
• Johansen, Finn-Eirik; Brautaset, Trygve; Aune, Marie Hjelmseth; Patriksson, Alexandra; Falkenberg, Liv Eggset; Kleppe, Rune; Dick, Gunnar; Strand, Berit Løkensgard; Eijsink, Vincent; Røyne, Anja. (2018) Centre for Digital Life Norway - Annual report 2017. Senter for Digialt Liv Norge
  Research report
• Stafsnes, Marit Hallvardsdotter; Røst, Lisa Marie; Bruheim, Per. (2018) Improved phosphometabolome profiling applying isotope dilution strategy and capillary ion chromatography-tandem mass spectrometry. Journal of chromatography. B
  Academic article
• Søgaard, Caroline Krogh; Blindheim, Augun; Røst, Lisa Marie; Petrovic, Voin; Nepal, Anala; Bachke, Siri; Liabakk, Nina-Beate; Gederaas, Odrun Arna; Viset, Trond; Arum, Carl-Jørgen. (2018) "Two hits - one stone" increased efficacy of cisplatin-based therapies by targeting PCNA's role in both DNA repair and cellular signaling. OncoTarget
  Academic article
• Olaisen, Camilla; Kvitvang, Hans Fredrik Nyvold; Lee, Sungmin; Almaas, Eivind; Bruheim, Per; Drabløs, Finn; Otterlei, Marit. (2018) The role of PCNA as a scaffold protein in cellular signaling is functionally conserved between yeast and humans. FEBS Open Bio
  Academic article

2015

• Mühlroth, Alice; Assimi, AE; Røkke, Gunvor; Despres, Julie; Winge, Per; Bruheim, Per; Hohmann-Marriott, Martin Frank; Vadstein, Olav; Bones, Atle M.. (2015) Transcriptional regulation of lipid accumulation in phosphorus limited Nannochloropsis oceanica. European journal of phycology
  Conference abstract
• Sreevidya, Meesala; Gopalakrishnan, Subramaniam; Melø, Torun Margareta; Simic, Nebojsa; Bruheim, Per; Sharma, Mamta; Srinivas, Vadlamudi; Alekhya, Gottumukkala. (2015) Biological control of Botrytis cinerea and plant growth promotion potential by Penicillim citrinum in chickpea (Cicer arietinum L.). Biocontrol science and technology (Print)
  Academic article
• Kvitvang, Hans Fredrik Nyvold; Bruheim, Per. (2015) Fast filtration sampling protocol for mammalian suspension cells tailored for phosphometabolome profiling by capillary ion chromatography - tandem mass spectrometry. Journal of chromatography. B
  Academic article
• Lien, Stina Katrine; Niedenführ, Sebastian; Sletta, Håvard; Nöh, Katharina; Bruheim, Per. (2015) Fluxome study of Pseudomonas fluorescens reveals major reorganisation of carbon flux through central metabolic pathways in response to inactivation of the anti-sigma factor MucA. BMC Systems Biology
  Academic article
• Giskeødegård, Guro F.; Hansen, Ailin Falkmo; Bertilsson, Helena; Villa Gonzalez, Susana; Kristiansen, Kåre Andre; Bruheim, Per; Mjøs, Svein Are; Angelsen, Anders; Bathen, Tone Frost; Tessem, May-Britt. (2015) Metabolic markers in blood can separate prostate cancer from benign prostatic hyperplasia. British Journal of Cancer
  Academic article
• Janecková, Hana; Kalivodova, Alzbeta; Najdekr, Lukas; Friedecký, David; Hron, Karel; Bruheim, Per; Adam, Tomás. (2015) Untargeted metabolomic analysis of urine samples in the diagnosis of some inherited metabolic disorders. Biomedical Papers of the Faculty of Medicine of Palacky University
  Academic article

2014

• Kvitvang, Hans Fredrik Nyvold; Kristiansen, Kåre Andre; Lien, Stina Katrine; Bruheim, Per. (2014) Quantitative Analysis of Amino and Organic Acids by Methyl Chloroformate Derivatization and GC-MS/MS Analysis.
  Academic chapter
• Gederaas, Odrun Arna; Søgaard, Caroline Danielsen; Viset, Trond; Bachke, Siri; Bruheim, Per; Arum, Carl-Jørgen; Otterlei, Marit. (2014) Increased anticancer efficacy of intravesical mitomycin C therapy when combined with a PCNA targeting peptide. Translational Oncology
  Academic article
• Kvitvang, Hans Fredrik Nyvold; Kristiansen, Kåre Andre; Bruheim, Per. (2014) Assessment of capillary anion exchange ion chromatography tandem mass spectrometry for the quantitative profiling of the phosphometabolome and organic acids in biological extracts. Journal of Chromatography A
  Academic article

2013

• Stafsnes, Marit Hallvardsd; Bruheim, Per. (2013) Pigmented Marine Heterotrophic Bacteria: Occurrence, Diversity, and Characterization of Pigmentation.
  Academic chapter
• Pettersen, Ragnhild; Johnsen, Geir; Bruheim, Per; Andreassen, Trygve. (2013) Development of hyperspectral imaging as a bio-optical taxonomic tool for pigmented marine organisms. Organisms Diversity & Evolution
  Academic article
• Bruheim, Per; Kvitvang, Hans Fredrik Nyvold; Villas-Boas, Silas G.. (2013) Stable isotope coded derivatizing reagents as internal standards in metabolite profiling. Journal of Chromatography A
  Academic literature review
• Borgos, Sven Even F.; Bordel, Sergio; Sletta, Håvard; Ertesvåg, Helga; Jakobsen, Øyvind Mejdell; Bruheim, Per; Ellingsen, Trond Erling; Nielsen, Jens; Valla, Svein. (2013) Mapping global effects of the anti-sigma factor MucA in Pseudomonas fluorescens SBW25 through genome-scale metabolic modeling. BMC Systems Biology
  Academic article
• Stafsnes, Marit Hallvardsd; Dybwad, Marius; Brunsvik, Anders; Bruheim, Per. (2013) Large scale MALDI-TOF MS based taxa identification to identify novel pigment producers in a marine bacterial culture collection. Antonie van Leeuwenhoek. International Journal of General and Molecular Microbiology
  Academic article

2012

• Almaas, Eivind; Bruheim, Per; Lale, Rahmi; Valla, Svein. (2012) Dynamics and robustness of metabolic networks: A systems biology review of Escherichia coli metabolism.
  Academic chapter
• Wojtowicz, Petr; Zrostlíková, Jitka; Šťastná, Veronika; Dostálová, Eva; Zídková, Lenka; Bruheim, Per; Adam, Tomáš. (2012) Comprehensive Two-Dimensional Gas Chromatography Coupled to Time-of-Flight Mass Spectrometry in Human Metabolomics.
  Academic chapter
• Tøndervik, Anne; Bruheim, Per; Berg, Laila; Ellingsen, Trond Erling; Kotlar, Hans Kristian; Valla, Svein; Throne-Holst, Mimmi. (2012) Ralstonia sp U2 naphthalene dioxygenase and Comamonas sp JS765 nitrobenzene dioxygenase show differences in activity towards methylated naphthalenes. Journal of Bioscience and Bioengineering
  Academic article
• Janecková, Hana; Hron, Karel; Wojtowicz, Petr; Hlídková, Eva; Baresová, Anna; Friedecký, David; Zídková, Lenka; Hornik, Petr; Behúlová, Darina; Procházková, Dagmar. (2012) Targeted metabolomic analysis of plasma samples for the diagnosis of inherited metabolic disorders. Journal of Chromatography A
  Academic article
• Lien, Stina Katrine; Kvitvang, Hans Fredrik Nyvold; Bruheim, Per. (2012) Utilization of a deuterated derivatization agent to synthesize internal standards for gas chromatography-tandem mass spectrometry quantification of silylated metabolites. Journal of Chromatography A
  Academic article
• Fremstedal, Ane Sofia Viset; Bruheim, Per; Sletta, Håvard; Johnsen, Geir. (2012) Utvikling og optimalisering av protokoll for massespektrometrisk metabolsk profilering av adherente humane celler. Norges teknisk-naturvitenskapelige universitet
  Master thesis
• Elde, Anette; Pettersen, Ragnhild; Bruheim, Per; Järnegren, Johanna; Johnsen, Geir. (2012) Pigmentation and Spectral Absorbance Signatures in Deep-Water Corals from the Trondheimsfjord, Norway. Marine Drugs
  Academic article
• Lien, Stina Katrine; Sletta, Håvard; Ellingsen, Trond Erling; Valla, Svein; Correa, Elon; Goodacre, Royston; Vernstad, Kai; Borgos, Sven Even F.; Bruheim, Per. (2012) Investigating alginate production and carbon utilization in Pseudomonas fluorescens SBW25 using mass spectrometry-based metabolic profiling. Metabolomics
  Academic article
• Wentzel, Alexander; Bruheim, Per; Øverby, Anders; Jakobsen, Øyvind Mejdell; Sletta, Håvard; Omara, Walid A.M.; Hodgson, David A.; Ellingsen, Trond Erling. (2012) Optimized submerged batch fermentation strategy for systems scale studies of metabolic switching in Streptomyces coelicolor A3(2). BMC Systems Biology
  Academic article
• Wentzel, Alexander; Sletta, Håvard; Wellington, E.M.H.; Ellingsen, Trond Erling; Bruheim, Per. (2012) Intracellular metabolite pool changes in response to nutrient depletion induced metabolic switching in Streptomyces coelicolor. Metabolites
  Academic article
• Dybwad, Marius; Granum, Per Einar; Bruheim, Per; Blatny, Janet Martha. (2012) Characterization of airborne bacteria at an underground subway station. Applied and Environmental Microbiology
  Academic article

2011

• Svee, Kristin; Eftedal, Ingrid; Bruheim, Per. (2011) Genetisk disposisjon for dykkersyke? Uttrykk av hypoksirelaterte gener i abdominal aorta fra rotte etter simulerte dykk. NTNU
  Master thesis
• Sletta, Håvard; Klinkenberg, Geir; Winnberg, Asgeir; Kvitvang, Hans Fredrik Nyvold; Nilsen, Marianne Bakke; Krokan, Hans Einar; Otterlei, Marit; Bruheim, Per. (2011) A new high resolution screening method for study of phenotype stress responses of Saccharomyces cerevisae mutants. Journal of Microbiological Methods
  Academic article
• Bruheim, Per. (2011) “We focus most on the approximately 2000 baker's yeast genes that are closest to human genes.”. Gemini
  Popular science article
• Kvitvang, Hans Fredrik Nyvold; Andreassen, Trygve; Adam, Tomas; Villas-Boas, Silas G.; Bruheim, Per. (2011) Highly sensitive GC/MS/MS method for quantitation of amino and nonamino organic acids. Analytical Chemistry
  Academic article
• Vijayabharathi, Rajendran; Bruheim, Per; Andreassen, Trygve; Raja, Duraisamy Senthil; Devi, Palanisamy Bruntha; Sathyabama, Sathyaseelan; Priyadarisini, Venkatesan Brindha. (2011) Assessment of resistomycin, as an anticancer compound isolated and characterized from Streptomyces aurantiacus AAA5. Journal of Microbiology
  Academic article
• Klinkenberg, Geir; Sletta, Håvard; Fjærvik, Espen; Zahlsen, Kolbjørn; Bruheim, Per. (2011) Two-dimensional LC-MS fractioning and cross-matching of mass spectrometric data for rational identification of bioactive compounds in crude extracts. Journal of Separation Science
  Academic article

2010

• Stafsnes, Marit Hallvardsdotter; Josefsen, Kjell D.; Kildahl-Andersen, Geir; Valla, Svein; Ellingsen, Trond E.; Bruheim, Per. (2010) Isolation and Characterization of Marine Pigmented Bacteria from Norwegian Coastal Waters and Screening for Carotenoids with UVA-Blue Light Absorbing Properties. Journal of Microbiology
  Academic article
• Volkova, Yulia A.; Averina, Elena B.; Grishin, Yuri K.; Bruheim, Per; Kuznetsova, Tamara S.; Zefirov, Nikolai S.. (2010) Unexpected Heterocyclization of Electrophilic Alkenes by Tetranitromethane in the Presence of Triethylamine. Synthesis of 3-Nitroisoxazoles. Journal of Organic Chemistry
  Academic article
• Nieselt, Kay; Battke, Florian; Herbig, Alexander; Bruheim, Per; Wentzel, Alexander; Jakobsen, Øyvind Mejdell; Sletta, Håvard; Alam, Mohammad T.; Merlo, Maria E.; Moore, Jonathan. (2010) The dynamic architecture of the metabolic switch in Streptomyces coelicolor. BMC Genomics
  Academic article
• Mørkved, Eva Henmo; Andreassen, Trygve; Fröhlich, Roland; Mo, Frode; Bruheim, Per. (2010) Unsymmetrical zinc azaphthalocyanines, peripherally substituted with thiophen-2-yl and 2-functionalized phenoxy groups. Polyhedron
  Academic article
• Bruheim, Per. (2010) Gjær som pasienter. Gemini
  Popular science article
• Netzer, Roman; Stafsnes, Marit Hallvardsdotter; Andreassen, Trygve; Goksøyr, Audun; Bruheim, Per; Brautaset, Trygve. (2010) Biosynthetic Pathway for g-Cyclic Sarcinaxanthin in Micrococcus luteus: Heterologous Expression and Evidence for Diverse and Multiple Catalytic Functions of C50 Carotenoid Cyclases. Journal of Bacteriology
  Academic article

2009

• Jørgensen, Hanne; Degnes, Kristin; Sletta, Håvard; Fjærvik, Espen; Dikiy, Alexander; Dikiy, Alexander; Herfindal, Lars; Bruheim, Per; Klinkenberg, Geir; Bredholt, Harald. (2009) Biosynthesis of Macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit. Chemistry and Biology
  Academic article
• Mørkved, Eva Henmo; Andreassen, Trygve; Bruheim, Per. (2009) Zinc azaphthalocyanines with pyridin-3-yloxy peripheral substituents. Polyhedron
  Academic article
• Jørgensen, Hanne; Fjærvik, Espen; Hakvåg, Sigrid; Bruheim, Per; Bredholt, Harald; Klinkenberg, Geir; Ellingsen, Trond Erling; Zotchev, Sergey. (2009) Candicidin Biosynthesis Gene Cluster Is Widely Distributed among Streptomyces spp. Isolated from the Sediments and the Neuston Layer of the Trondheim Fjord, Norway. Applied and Environmental Microbiology
  Academic article
• Bruheim, Per; Sletta, Håvard; Zahlsen, Kolbjørn; Bathen, Tone Frost; Gribbestad, Ingrid S. (2009) metabolomics - et spennende verktøy i medisinsk og biologisk forskning. NBS-nytt
  Popular science article
• Stockmann, Vegar; Bakke, Jan Magnus; Bruheim, Per; Fiksdahl, Anne. (2009) Formation of new 4-isocyanobut-2-enenitriles by thermal ring cleavage of 3-pyridyl azides. Tetrahedron
  Academic article

2008

• Fuglseth, Erik; Sundby, Eirik; Bruheim, Per; Hoff, Bård Helge. (2008) Asymmetric reduction using (R)-MeCBS and determination of absolute configuration of para-substituted 2-fluoroarylethanols. Tetrahedron: asymmetry
  Academic article
• Simon, Sebastien Charles; Nordgård, Erland; Bruheim, Per; Sjøblom, Johan. (2008) Determination of C-80 tetra-acid content in calcium naphthenate deposits. Journal of Chromatography A
  Academic article
• Fuglseth, Erik; Sundby, Eirik; Bruheim, Per; Hoff, Bård Helge. (2008) Asymmetric reduction using (R)-MeCBS and determination of absolute configuration of para-substituted 2-fluoroarylethanols. Tetrahedron: asymmetry
  Academic article

2007

• Villas-Boas, Silas G.; Bruheim, Per. (2007) The potential of metabolomics tools in bioremediation studies. Omics
  Academic literature review
• Villas-Boas, Silas G.; Bruheim, Per. (2007) Cold glycerol–saline: The promising quenching solution for accurate intracellular metabolite analysis of microbial cells. Analytical Biochemistry
  Academic article

2006

• Holtan, Synnøve; Bruheim, Per; Skjåk-Bræk, Gudmund. (2006) Mode of action and subsite studies of the guluronan block forming mannuronan C-5 epimerases AlgE1 and AlgE6. Biochemical Journal
  Academic article
• Otterlei, Marit; Bruheim, Per; Ahn, Byungchan; Bussen, Wendy; Karmakar, Parimal; Baynton, Kathy; Bohr, Vilhelm A.. (2006) Werner syndrome protein participates in a complex with RAD51, RAD54, RAD54B and ATR in response to ICL-induced replication arrest. Journal of Cell Science
  Academic article

2005

• Sletta, Håvard; Bruheim, Per; Borgos, Sven Even F.; Sekurova, Olga; Grasdalen, Hans; Aune, Randi; Zotchev, Sergey; Ellingsen, Trond Erling. (2005) Nystatin biosynthesis and transport: nysH and nysG genes encoding a putative ABC transporter system in Streptomyces noursei ATCC 11455 are required for efficient conversion of 10-deoxynystatin to nystatin. Antimicrobial Agents and Chemotherapy
  Academic article

2004

• Bruheim, Per; Borgos, Sven Even F.; Tsan, Pascale; Sletta, Håvard; Ellingsen, Trond Erling; Lancelin, Jean-Marc; Zotchev, Sergey. (2004) Chemical diversity of polyene macrolides produced by Streptomyces noursei ATCC 11455 and recombinant strain ERD44 with genetically altered polyketide synthase NysC. Antimicrobial Agents and Chemotherapy
  Academic article

2003

• Butler, M.; Takano, E.; Bruheim, Per; Jovetic, Srdjan; Marinelli, Flavia; Bibb, Mervyn J.. (2003) Deletion of scbA enhances antibiotic production in Streptomyces lividans. Applied Microbiology and Biotechnology
  Academic article
• Gunnarsson, Nina; Bruheim, Per; Nielsen, Jens. (2003) Production of the glycopeptide antibiotic A40926 by Nonomuraea sp. ATCC 39727: influence of medium composition in batch fermentation. Journal of Industrial Microbiology & Biotechnology
  Academic article
• Robin, J.; Bruheim, Per; Nielsen, M.L.; Noorman, H.; Nielsen, Jens. (2003) Continuous cultivations of a Pencillium chrysogenum strain expressing the expandase gene from Streptomyces clavuligerus: Kinetics of adipoyl-7-aminodeacetyoxycephalosporanic acid and byproduct formations. Biotechnology and Bioengineering
  Academic article

2002

• Butler, M.; Bruheim, Per; Jovetic, Srdjan; Marinelli, Flavia; Postma, Pieter W.; Bibb, Mervyn J.. (2002) Engineering of primary carbon metabolism for improved antibiotic production in Streptomyces lividans. Applied and Environmental Microbiology
  Academic article
• Bruheim, Per; Sletta, Håvard; Bibb, M.J.; White, J.; Levine, David William. (2002) High-yield actinorhodin production in fed-batch culture by a Streptomyces lividans strain overexpressing the pathway-specific activator gene actII-ORF4. Journal of Industrial Microbiology & Biotechnology
  Academic article
• Bredholt, Harald; Bruheim, Per; Potocky, Martin; Eimhjellen, Kjell. (2002) Hydrophobicity development, alkane oxidation, and crude-oil emulsification in a Rhodococcus species. Canadian Journal of Microbiology (print)
  Academic article
• Bruheim, Per; Butler, M.; Ellingsen, Trond E.. (2002) A theoretical analysis of the biosynthesis of actinorhodin in a hyper-producing Streptomyces lividans strain cultivated on various carbon sources. Applied Microbiology and Biotechnology
  Academic article
• Brautaset, Trygve; Bruheim, Per; Sletta, Håvard; Hagen, Lars; Ellingsen, Trond E.; Strøm, Arne Reidar; Valla, Svein; Zotchev, Sergey. (2002) Hexaene derivatives of nystatin produced as a result of an induced rearrangement within the nysC polyketide synthase gene in S. noursei ATCC 11455. Chemistry and Biology
  Academic article

2000

• Bruheim, Per; Eimhjellen, Kjell. (2000) Effects of non-ionic surfactants on the uptake and hydrolysis of fluoresceindiacetate by alkane-oxidizing bacteria. Canadian Journal of Microbiology (print)
  Academic article
• Bruheim, Per. (2000) Metabolic engineering - fremtidens verktøy for utvikling av industrielle bioteknologiske prosesser?. NBS-nytt
  Popular science article

1999

• Bruheim, Per; Bredholt, Harald; Eimhjellen, Kjell. (1999) Effects of surfactant mixtures, including Corexit 9527, on bacterial oxidation of acetate and alkanes in crude oil. Applied and Environmental Microbiology
  Academic article

1998

• Bruheim, Per; Eimhjellen, Kjell. (1998) Chemically emulsified crude oil as substrate for bacterial oxdidation : differences in species response. Canadian Journal of Microbiology (print)
  Academic article
• Bredholt, Harald; Josefsen, Kjell; Vatland, Arild; Bruheim, Per; Eimhjellen, Kjell. (1998) Emulsification of crude oil by an alkane-oxidizing Rhodococcus species isolated from seawater. Canadian Journal of Microbiology (print)
  Academic article

1997

• Bruheim, Per; Bredholt, Harald; Eimhjellen, Kjell. (1997) Bacterial degradation of emulsified crude oil and the effect of various surfactants. Canadian Journal of Microbiology (print)
  Academic article

1996

• Thu, Beate; Bruheim, Per; Espevik, Terje; Smidsrød, Olav; Soon-Shiong, Patrick; Skjåk-Bræk, Gudmund. (1996) Alginate polycation microcapsules. II, Some functional properties. Biomaterials
  Academic article
• Thu, Beate; Bruheim, Per; Espevik, Terje; Smidsrød, Olav; Soon-Shiong, P.; Skjåk-Bræk, Gudmund. (1996) Alginate polycation microcapsules. I, Interaction between alginate and polycation. Biomaterials
  Academic article

1991

• Stokke, Bjørn Torger; Smidsrød, Olav; Bruheim, Per; Skjåk-Bræk, Gudmund. (1991) Distribution of uronate residues in alginate chains in relation to alginate gelling properties. Macromolecules
  Academic article