Journal publications

• Ianevski, Aleksandr; Simonsen, Ronja Meyer; Myhre, Vegard; Tenson, Tanel; Oksenych, Valentyn; Bjørås, Magnar; Kainov, Denis. (2022) DrugVirus.info 2.0: an integrative data portal for broad-spectrum antivirals (BSA) and BSA-containing drug combinations (BCCs). Nucleic Acids Research (NAR).
• Ianevski, Aleksandr; Yao, Rouan; Simonsen, Ronja Meyer; Myhre, Vegard; Ravlo, Erlend; Kaynova, Gerda D.; Zusinaite, Eva; White, Judith M.; Polyak, Stephen J.; Oksenych, Valentyn; Windisch, Marc P.; Pan, Qiuwei; Lastauskienė, Eglė; Vitkauskienė, Astra; Matukevičius, Algimantas; Tenson, Tanel; Bjørås, Magnar; Kainov, Denis. (2022) Mono- and combinational drug therapies for global viral pandemic preparedness. iScience. vol. 25 (4).
• Li, Pengfei; Li, Yunlong; Wang, Yijin; Liu, Jiaye; Lavrijsen, Marla; Li, Yang; Zhang, Ruyi; Verstegen, Monique M.A.; Wang, Yining; Li, Tian-Cheng; Ma, Zhongren; Kainov, Denis; Bruno, Marco J.; de Man, Robert A.; van der Laan, Luc J.W.; Peppelenbosch, Maikel P.; Pan, Qiuwei. (2022) Recapitulating hepatitis E virus-host interactions and facilitating antiviral drug discovery in human liver-derived organoids. Science Advances. vol. 8 (3).
• Ianevski, Aleksandr; Yao, Rouan; Lysvand, Hilde; Grødeland, Gunnveig; Legrand, Nicolas; Oksenych, Valentyn; Zusinaite, Eva; Tenson, Tanel; Bjørås, Magnar; Kainov, Denis E.. (2021) Nafamostat–interferon-α combination suppresses sars-cov-2 infection in vitro and in vivo by cooperatively targeting host tmprss2. Viruses. vol. 13:1768 (9).
• Ianevski, Aleksandr; Yao, Rouan; Zusinaite, Eva; Lello, Laura Sandra; Wang, Sainan; Jo, Eunji; Yang, Jaewon; Ravlo, Erlend; Wang, Wei; Lysvand, Hilde; Løseth, Kirsti; Oksenych, Valentyn; Tenson, Tanel; Windisch, Marc P.; Poranen, Minna M.; Nieminen, Anni I.; Nordbø, Svein Arne; Fenstad, Mona H.; Grødeland, Gunnveig; Aukrust, Pål; Trøseid, Marius; Kantele, Anu; Lastauskienė, Eglė; Vitkauskienė, Astra; Legrand, Nicolas; Merits, Andres; Bjørås, Magnar; Kainov, Denis. (2021) Synergistic interferon-alpha-based combinations for treatment of sars-cov-2 and other viral infections. Viruses. vol. 13:2489 (12).
• Ianevski, Aleksandr; Yao, Rouan; Zusinaite, Eva; Lysvand, Hilde; Oksenych, Valentyn; Tenson, Tanel; Bjørås, Magnar; Kainov, Denis. (2021) Active components of commonly prescribed medicines affect influenza a virus–host cell interaction: A pilot study. Viruses. vol. 13 (8).
• Ladner, Jason T.; Henson, Sierra N.; Boyle, Annalee S.; Engelbrektson, Anna L.; Fink, Zane W.; Rahee, Fatima; D'ambrozio, Jonathan; Schaecher, Kurt E.; Stone, Mars; Dong, Wenjuan; Dadwal, Sanjeet; Yu, Jianhua; Caligiuri, Michael A.; Cieplak, Piotr; Bjørås, Magnar; Fenstad, Mona H.; Nordbø, Svein Arne; Kainov, Denis; Muranaka, Norihito; Chee, Mark S.; Shiryaev, Sergey A.; Altin, John A.. (2021) Epitope-resolved profiling of the SARS-CoV-2 antibody response identifies cross-reactivity with endemic human coronaviruses. Cell Reports Medicine. vol. 2 (1).
• Li, Yunlong; Miao, Zhijiang; Li, Pengfei; Zhang, Ruyi; Kainov, Denis; Ma, Zhongren; de Man, Robert A.; Peppelenbosch, Maikel Petrus; Pan, Qiuwei. (2021) Ivermectin effectively inhibits hepatitis E virus replication, requiring the host nuclear transport protein importin α1. Archives of Virology. vol. 166 (7).
• Meehyun, Ko; Chang, Soo Young; Byun, Soo Young; Ianevski, Aleksandr; Choi, Inhee; Pham Hung, Anne-Laure; Ravlo, Erlend; Wang, Wei; Bjørås, Magnar; Kainov, Denis; Shum, David; Min, Ji-Young; Windisch, Marc P.. (2021) Screening of FDA-Approved Drugs Using a MERS-CoV Clinical Isolate from South Korea Identifies Potential Therapeutic Options for COVID-19. Viruses.
• Rabben, Hanne-Line; Andersen, Gøran Troseth; Ianevski, Aleksandr; Olsen, Magnus Kringstad; Kainov, Denis; Grønbech, Jon Erik; Wang, Timothy Cragin; Chen, Duan; Zhao, Chun-Mei. (2021) Computational Drug Repositioning and Experimental Validation of Ivermectin in Treatment of Gastric Cancer. Frontiers in Pharmacology. vol. 12.
• Rabben, Hanne-Line; Andersen, Gøran Troseth; Olsen, Magnus Kringstad; Øverby, Anders; Ianevski, Aleksandr; Kainov, Denis; Wang, Timothy Cragin; Lundgren, Steinar; Grønbech, Jon Erik; Chen, Duan; Zhao, Chun-Mei. (2021) Neural signaling modulates metabolism of gastric cancer. iScience. vol. 24 (2).
• White, Judith M.; Schiffer, Joshua T.; Bender Ignacio, Rachel A.; Xu, Shuang; Kainov, Denis; Ianevski, Aleksandr; Aittokallio, Tero Antero; Frieman, Matthew; Olinger, Gene G.; Polyak, Stephen J.. (2021) Drug Combinations as a First Line of Defense against Coronaviruses and Other Emerging Viruses. mBio. vol. 12 (6).
• Yang, Jaewon; König, Alexander; Park, Soonju; Jo, Eunji; Sung, Pil Soo; Yoon, Seung Kew; Zusinaite, Eva; Kainov, Denis; Shum, David; Windisch, Marc Peter. (2021) A new high-content screening assay of the entire hepatitis B virus life cycle identifies novel antivirals. JHEP Reports. vol. 3 (4).
• Anderssen, Petter Inge; Ianevski, Aleksandr; Lysvand, Hilde; Vitkauskiene, Astra; Oksenych, Valentyn; Bjørås, Magnar; Telling, Kaidi; Lutsar, Irja; Dumpis, Uga; Irie, Yasuhiko; Tenson, Tanel; Kantele, Anu; Kainov, Denis. (2020) Discovery and development of safe-in-man broad-spectrum antiviral agents. International Journal of Infectious Diseases. vol. 93.
• Chen, Sunrui; Wang, Yining; Li, Pengfei; Yin, Yuebang; Bijvelds, Marcel J.; de Jonge, Hugo R.; Peppelenbosch, Maikel Petrus; Kainov, Denis; Pan, Qiuwei. (2020) Drug screening identifies gemcitabine inhibiting rotavirus through alteration of pyrimidine nucleotide synthesis pathway. Antiviral Research. vol. 180.
• Ianevski, Aleksandr; Kulesskiy, Evgeny; Krpina, Klara; Lou, Guofeng; Aman, Yahyah; Bugai, Andrii; Aasumets, Koit; Akimov, Yevhen; Bulanova, Daria; Gildemann, Kiira; Arutyunyan, Albert F.; Susova, Olga Yu.; Zhuze, Alexei L.; Ji, Ping; Wang, Wei; Holien, Toril; Bugge, Marit; Zusinaite, Eva; Oksenych, Valentyn; Lysvand, Hilde; Gerhold, Joachim M.; Bjørås, Magnar; Johansen, Pål; Waage, Anders; Heckman, Caroline A.; Fang, Fei; Kainov, Denis. (2020) Chemical, Physical and Biological Triggers of Evolutionary Sonserved Bcl-xL-Mediated Apoptosis. Cancers. vol. 12 (6).
• Ianevski, Aleksandr; Yao, Rouan; Biza, Svetlana; Zusinaite, Eva; Mannik, Andres; Kivi, Gaily; Planken, Anu; Kurg, Kristiina; Tombak, Eva-Maria; Ustav, Mart Jr; Shtaida, Nastassia; Kulesskiy, Evgeny; Jo, Eunji; Yang, Jaewon; Lysvand, Hilde; Løseth, Kirsti; Oksenych, Valentyn; Aas, Per Arne; Tenson, Tanel; Vitkauskienė, Astra; Windisch, Marc P; Fenstad, Mona H.; Nordbø, Svein Arne; Ustav, Mart; Bjørås, Magnar; Kainov, Denis. (2020) Identification and Tracking of Antiviral Drug Combinations. Viruses. vol. 12 (10).
• Ianevski, Aleksandr; Yao, Rouan; Fenstad, Mona H.; Biza, Svetlana; Zusinaite, Eva; Reisberg, Tuuli; Lysvand, Hilde; Løseth, Kirsti; Landsem, Veslemøy Malm; Fossum, Janne; Erlandsen, Sten Even; Aas, Per Arne; Hagen, Lars; Pettersen, Caroline Hild; Tenson, Tanel; Afset, Jan Egil; Nordbø, Svein Arne; Bjørås, Magnar; Kainov, Denis; Oksenych, Valentyn. (2020) Potential Antiviral Options against SARS-CoV-2 Infection. Viruses. Viruses.
• Li, Yunlong; Li, Pengfei; Li, Yang; Zhang, Ruyi; Yu, Peifa; Ma, Zhongren; Kainov, Denis; de Man, Robert A.; Peppelenbosch, Maikel P.; Pan, Qiuwei. (2020) Drug screening identified gemcitabine inhibiting hepatitis E virus by inducing interferon-like response via activation of STAT1 phosphorylation. Antiviral Research. vol. 184:104967.
• Anderssen, Petter Inge; Krpina, Klara; Ianevski, Aleksandr; Shtaida, Nastassia; Jo, Eunji; Yang, Jaewon; Koit, Sandra; Tenson, Tanel; Hukkanen, Veijo; Anthonsen, Marit Walbye; Bjørås, Magnar; Evander, Magnus; Windisch, Marc P; Zusinaite, Eva; Kainov, Denis. (2019) Novel antiviral activities of obatoclax, emetine, niclosamide, brequinar, and homoharringtonine. Viruses. vol. 11 (10).