2022

• Ianevski, Aleksandr; Simonsen, Ronja Meyer; Myhre, Vegard; Tenson, Tanel; Oksenych, Valentyn; Bjørås, Magnar; Kainov, Denis. (2022) DrugVirus.info 2.0: an integrative data portal for broad-spectrum antivirals (BSA) and BSA-containing drug combinations (BCCs). Nucleic Acids Research (NAR). volum 50 (1).
  Academic article
• Ianevski, Aleksandr; Yao, Rouan; Simonsen, Ronja Meyer; Myhre, Vegard; Ravlo, Erlend; Kaynova, Gerda D.; Zusinaite, Eva; White, Judith M.; Polyak, Stephen J.; Oksenych, Valentyn; Windisch, Marc P.; Pan, Qiuwei; Lastauskienė, Eglė; Vitkauskienė, Astra; Matukevičius, Algimantas; Tenson, Tanel; Bjørås, Magnar; Kainov, Denis. (2022) Mono- and combinational drug therapies for global viral pandemic preparedness. iScience. volum 25 (4).
  Scientific translation/review
• Ianevski, Aleksandr; Zusinaite, Eva; Tenson, Tanel; Oksenych, Valentyn; Wang, Wei; Afset, Jan Egil; Bjørås, Magnar; Kainov, Denis. (2022) Novel Synergistic Anti-Enteroviral Drug Combinations. Viruses. volum 14 (9).
  Academic article
• Kainov, Denis; Oksenych, Valentyn. (2022) Broad-Spectrum Antivirals and Antiviral Combinations: An Editorial Update. Viruses. volum 14 (10).
  Editorial
• Li, Pengfei; Li, Yunlong; Wang, Yijin; Liu, Jiaye; Lavrijsen, Marla; Li, Yang; Zhang, Ruyi; Verstegen, Monique M.A.; Wang, Yining; Li, Tian-Cheng; Ma, Zhongren; Kainov, Denis; Bruno, Marco J.; de Man, Robert A.; van der Laan, Luc J.W.; Peppelenbosch, Maikel P.; Pan, Qiuwei. (2022) Recapitulating hepatitis E virus-host interactions and facilitating antiviral drug discovery in human liver-derived organoids. Science Advances. volum 8 (3).
  Academic article
• Nordbø, Svein Arne; Linh, Hoang; Krokstad, Sidsel; Kainov, Denis; Sagvik, Eli Oline. (2022) Rask eliminasjon av SARS-CoV-2 hos fullvaksinert pasient. www.tidsskriftet.no. volum 142 (3).
  Short communication
• Oksenych, Valentyn; Kainov, Denis. (2022) Broad-Spectrum Antivirals and Antiviral Drug Combinations. Viruses. volum 14 (2).
  Editorial
• Ravlo, Erlend; Evensen, Lasse; Sanson, Gorm; Hildonen, Siri; Ianevski, Aleksandr; Skjervold, Per Olav; Ji, Ping; Wang, Wei; Kaarbø, Mari; Kaynova, Gerda Dominyka; Kainov, Denis; Bjørås, Magnar. (2022) Antiviral Immunoglobulins of Chicken Egg Yolk for Potential Prevention of SARS-CoV-2 Infection. Viruses. volum 14 (10).
  Academic article

2021

• Ianevski, Aleksandr; Yao, Rouan; Lysvand, Hilde; Grødeland, Gunnveig; Legrand, Nicolas; Oksenych, Valentyn; Zusinaite, Eva; Tenson, Tanel; Bjørås, Magnar; Kainov, Denis E.. (2021) Nafamostat–interferon-α combination suppresses sars-cov-2 infection in vitro and in vivo by cooperatively targeting host tmprss2. Viruses. volum 13:1768 (9).
  Academic article
• Ianevski, Aleksandr; Yao, Rouan; Zusinaite, Eva; Lello, Laura Sandra; Wang, Sainan; Jo, Eunji; Yang, Jaewon; Ravlo, Erlend; Wang, Wei; Lysvand, Hilde; Løseth, Kirsti; Oksenych, Valentyn; Tenson, Tanel; Windisch, Marc P.; Poranen, Minna M.; Nieminen, Anni I.; Nordbø, Svein Arne; Fenstad, Mona H.; Grødeland, Gunnveig; Aukrust, Pål; Trøseid, Marius; Kantele, Anu; Lastauskienė, Eglė; Vitkauskienė, Astra; Legrand, Nicolas; Merits, Andres; Bjørås, Magnar; Kainov, Denis. (2021) Synergistic interferon-alpha-based combinations for treatment of sars-cov-2 and other viral infections. Viruses. volum 13:2489 (12).
  Academic article
• Ianevski, Aleksandr; Yao, Rouan; Zusinaite, Eva; Lysvand, Hilde; Oksenych, Valentyn; Tenson, Tanel; Bjørås, Magnar; Kainov, Denis. (2021) Active components of commonly prescribed medicines affect influenza a virus–host cell interaction: A pilot study. Viruses. volum 13 (8).
  Academic article
• Kainov, Denis; Oksenych, Valentyn. (2021) DNA Damage Response. Biomolecules.
  Editorial
• Ladner, Jason T.; Henson, Sierra N.; Boyle, Annalee S.; Engelbrektson, Anna L.; Fink, Zane W.; Rahee, Fatima; D'ambrozio, Jonathan; Schaecher, Kurt E.; Stone, Mars; Dong, Wenjuan; Dadwal, Sanjeet; Yu, Jianhua; Caligiuri, Michael A.; Cieplak, Piotr; Bjørås, Magnar; Fenstad, Mona H.; Nordbø, Svein Arne; Kainov, Denis; Muranaka, Norihito; Chee, Mark S.; Shiryaev, Sergey A.; Altin, John A.. (2021) Epitope-resolved profiling of the SARS-CoV-2 antibody response identifies cross-reactivity with endemic human coronaviruses. Cell Reports Medicine. volum 2 (1).
  Academic article
• Li, Yunlong; Miao, Zhijiang; Li, Pengfei; Zhang, Ruyi; Kainov, Denis; Ma, Zhongren; de Man, Robert A.; Peppelenbosch, Maikel Petrus; Pan, Qiuwei. (2021) Ivermectin effectively inhibits hepatitis E virus replication, requiring the host nuclear transport protein importin α1. Archives of Virology. volum 166 (7).
  Academic article
• Meehyun, Ko; Chang, Soo Young; Byun, Soo Young; Ianevski, Aleksandr; Choi, Inhee; Pham Hung, Anne-Laure; Ravlo, Erlend; Wang, Wei; Bjørås, Magnar; Kainov, Denis; Shum, David; Min, Ji-Young; Windisch, Marc P.. (2021) Screening of FDA-Approved Drugs Using a MERS-CoV Clinical Isolate from South Korea Identifies Potential Therapeutic Options for COVID-19. Viruses.
  Academic article
• Oksenych, Valentyn; Kainov, Denis. (2021) DNA Damage Response. Biomolecules. volum 11:123 (1).
  Editorial
• Rabben, Hanne-Line; Andersen, Gøran Troseth; Ianevski, Aleksandr; Olsen, Magnus Kringstad; Kainov, Denis; Grønbech, Jon Erik; Wang, Timothy Cragin; Chen, Duan; Zhao, Chun-Mei. (2021) Computational Drug Repositioning and Experimental Validation of Ivermectin in Treatment of Gastric Cancer. Frontiers in Pharmacology. volum 12.
  Academic article
• Rabben, Hanne-Line; Andersen, Gøran Troseth; Olsen, Magnus Kringstad; Øverby, Anders; Ianevski, Aleksandr; Kainov, Denis; Wang, Timothy Cragin; Lundgren, Steinar; Grønbech, Jon Erik; Chen, Duan; Zhao, Chun-Mei. (2021) Neural signaling modulates metabolism of gastric cancer. iScience. volum 24 (2).
  Academic article
• White, Judith M.; Schiffer, Joshua T.; Bender Ignacio, Rachel A.; Xu, Shuang; Kainov, Denis; Ianevski, Aleksandr; Aittokallio, Tero Antero; Frieman, Matthew; Olinger, Gene G.; Polyak, Stephen J.. (2021) Drug Combinations as a First Line of Defense against Coronaviruses and Other Emerging Viruses. mBio. volum 12 (6).
  Scientific translation/review
• Yang, Jaewon; König, Alexander; Park, Soonju; Jo, Eunji; Sung, Pil Soo; Yoon, Seung Kew; Zusinaite, Eva; Kainov, Denis; Shum, David; Windisch, Marc Peter. (2021) A new high-content screening assay of the entire hepatitis B virus life cycle identifies novel antivirals. JHEP Reports. volum 3 (4).
  Academic article
• Yao, Rouan; Ianevski, Aleksandr; Kainov, Denis. (2021) Safe-in-Man Broad Spectrum Antiviral Agents. Safe-in-Man Broad Spectrum Antiviral Agents.
  Academic chapter/article

2020

• Anderssen, Petter Inge; Ianevski, Aleksandr; Lysvand, Hilde; Vitkauskiene, Astra; Oksenych, Valentyn; Bjørås, Magnar; Telling, Kaidi; Lutsar, Irja; Dumpis, Uga; Irie, Yasuhiko; Tenson, Tanel; Kantele, Anu; Kainov, Denis. (2020) Discovery and development of safe-in-man broad-spectrum antiviral agents. International Journal of Infectious Diseases. volum 93.
  Scientific translation/review
• Chen, Sunrui; Wang, Yining; Li, Pengfei; Yin, Yuebang; Bijvelds, Marcel J.; de Jonge, Hugo R.; Peppelenbosch, Maikel Petrus; Kainov, Denis; Pan, Qiuwei. (2020) Drug screening identifies gemcitabine inhibiting rotavirus through alteration of pyrimidine nucleotide synthesis pathway. Antiviral Research. volum 180.
  Academic article
• Ianevski, Aleksandr; Kulesskiy, Evgeny; Krpina, Klara; Lou, Guofeng; Aman, Yahyah; Bugai, Andrii; Aasumets, Koit; Akimov, Yevhen; Bulanova, Daria; Gildemann, Kiira; Arutyunyan, Albert F.; Susova, Olga Yu.; Zhuze, Alexei L.; Ji, Ping; Wang, Wei; Holien, Toril; Bugge, Marit; Zusinaite, Eva; Oksenych, Valentyn; Lysvand, Hilde; Gerhold, Joachim M.; Bjørås, Magnar; Johansen, Pål; Waage, Anders; Heckman, Caroline A.; Fang, Fei; Kainov, Denis. (2020) Chemical, Physical and Biological Triggers of Evolutionary Sonserved Bcl-xL-Mediated Apoptosis. Cancers. volum 12 (6).
  Academic article
• Ianevski, Aleksandr; Yao, Rouan; Biza, Svetlana; Zusinaite, Eva; Mannik, Andres; Kivi, Gaily; Planken, Anu; Kurg, Kristiina; Tombak, Eva-Maria; Ustav, Mart Jr; Shtaida, Nastassia; Kulesskiy, Evgeny; Jo, Eunji; Yang, Jaewon; Lysvand, Hilde; Løseth, Kirsti; Oksenych, Valentyn; Aas, Per Arne; Tenson, Tanel; Vitkauskienė, Astra; Windisch, Marc P; Fenstad, Mona H.; Nordbø, Svein Arne; Ustav, Mart; Bjørås, Magnar; Kainov, Denis. (2020) Identification and Tracking of Antiviral Drug Combinations. Viruses. volum 12 (10).
  Academic article
• Ianevski, Aleksandr; Yao, Rouan; Fenstad, Mona H.; Biza, Svetlana; Zusinaite, Eva; Reisberg, Tuuli; Lysvand, Hilde; Løseth, Kirsti; Landsem, Veslemøy Malm; Fossum, Janne; Erlandsen, Sten Even; Aas, Per Arne; Hagen, Lars; Pettersen, Caroline Hild; Tenson, Tanel; Afset, Jan Egil; Nordbø, Svein Arne; Bjørås, Magnar; Kainov, Denis; Oksenych, Valentyn. (2020) Potential Antiviral Options against SARS-CoV-2 Infection. Viruses. Viruses.
  Academic article
• Li, Yunlong; Li, Pengfei; Li, Yang; Zhang, Ruyi; Yu, Peifa; Ma, Zhongren; Kainov, Denis; de Man, Robert A.; Peppelenbosch, Maikel P.; Pan, Qiuwei. (2020) Drug screening identified gemcitabine inhibiting hepatitis E virus by inducing interferon-like response via activation of STAT1 phosphorylation. Antiviral Research. volum 184:104967.
  Academic article

2019

• Anderssen, Petter Inge; Krpina, Klara; Ianevski, Aleksandr; Shtaida, Nastassia; Jo, Eunji; Yang, Jaewon; Koit, Sandra; Tenson, Tanel; Hukkanen, Veijo; Anthonsen, Marit Walbye; Bjørås, Magnar; Evander, Magnus; Windisch, Marc P; Zusinaite, Eva; Kainov, Denis. (2019) Novel antiviral activities of obatoclax, emetine, niclosamide, brequinar, and homoharringtonine. Viruses. volum 11 (10).
  Academic article
• Bösl, Korbinian; Ianevski, Aleksandr; Than, Thoa T.; Anderssen, Petter Inge; Kuivanen, Suvi; Teppor, Mona; Zusinaite, Eva; Dumpis, Uga; Vitkauskiene, Astra; Cox, Rebecca Jane; Kallio-Kokko, Hannimari; Bergqvist, Anders; Tenson, Tanel; Merits, Andres; Oksenych, Valentyn; Bjørås, Magnar; Anthonsen, Marit Walbye; Shum, David H.K.; Kaarbø, Mari; Vapalahti, Olli; Windisch, Marc P.; Superti-Furga, Giulio; Snijder, Berend; Kainov, Denis; Kandasamy, Richard Kumaran. (2019) Common nodes of virus-host interaction revealed through an integrated network analysis. Frontiers in Immunology. volum 10.
  Academic article
• Ianevski, Aleksandr; Anderssen, Petter Inge; Merits, Andres; Bjørås, Magnar; Kainov, Denis. (2019) Expanding the activity spectrum of antiviral agents. Drug Discovery Today. volum 24 (5).
  Scientific translation/review
• Ianevski, Aleksandr; Zusinaite, Eva; Shtaida, Nastassia; Kallio-Kokko, Hannimari; Valkonen, Mia; Kantele, Anu; Telling, Kaidi; Lutsar, Irja; Letjuka, Pille; Metelitsa, Natalja; Oksenych, Valentyn; Dumpis, Uga; Vitkauskiene, Astra; Stašaitis, Kestutis; Öhrmalm, Christina; Bondeson, Kåre; Bergqvist, Anders; Cox, Rebecca Jane; Tenson, Tanel; Merits, Andres; Kainov, Denis. (2019) Low temperature and low UV indexes correlated with peaks of influenza virus activity in Northern Europe during 2010-2018. Viruses. volum 11:207 (3).
  Academic article

2018

• Ianevski, Aleksandr; Zusinaite, Eva; Kuivanen, Suvi; Strand, Mårten; Lysvand, Hilde; Teppor, Mona; Kakkola, Laura; Paavilainen, Henrik; Laajala, Mira; Kallio-Kokko, Hannimari; Valkonen, Miia; Kantele, Anu; Telling, Kaidi; Lutsar, Irja; Letjuka, Pille; Metelitsa, Natalja; Oksenych, Valentyn; Bjørås, Magnar; Nordbø, Svein Arne; Dumpis, Uga; Vitkauskiene, Astra; Öhrmalm, Christina; Bondeson, Kåre; Bergqvist, Anders; Aittokallio, Tero; Cox, Rebecca Jane; Evander, Magnus; Hukkanen, Veijo; Marjomäki, Varpu; Julkunen, Ilkka; Vapalahti, Olli; Tenson, Tanel; Merits, Andres; Kainov, Denis. (2018) Novel activities of safe-in-human broad-spectrum antiviral agents. Antiviral Research. volum 154.
  Academic article
• Loevenich, Simon; Ianevski, Aleksandr; Oitmaa, Eneli; Kainov, Denis; Anthonsen, Marit Walbye. (2018) Single passage of human metapneumovirus in LLCMK2 cells does not affect viral protein-coding capacity. Microbiology Resource Announcements (MRA). volum 6:00440-18 (21).
  Short communication
• Zusinaite, Eva; Ianevski, Aleksandr; Niukkanen, Diana; Poranen, Minna M.; Bjørås, Magnar; Afset, Jan Egil; Tenson, Tanel; Velagapudi, Vidya; Merits, Andres; Kainov, Denis. (2018) A systems approach to study immuno- and neuro-modulatory properties of antiviral agents. Viruses. volum 10 (8).
  Scientific translation/review

2017

• Bulanova, Daria; Ianevski, Aleksandr; Bugai, Andrii; Akimov, Yevhen; Kuivanen, Suvi; Paavilainen, Henrik; Kakkola, Laura; Nandania, Jatin; Turunen, Laura; Ohman, Tiina; Ala-Hongisto, Hanna; Pesonen, Hanna M; Kuisma, Marika S; Honkimaa, Anni; Walton, Emma Louise; Oksenych, Valentyn; Lorey, Martina B.; Guschin, Dmitry; Shim, Jungmin; Kim, Jinhee; Than, Thoa T; Chang, So Young; Hukkanen, Veijo; Kulesskiy, Evgeny; Marjomaki, Varpu S; Julkunen, Ilkka; Nyman, Tuula Anneli; Matikainen, Sampsa; Saarela, Jani S; Sane, Famara; Hober, Didier; Gabriel, Gulsah; De Brabander, Jef K; Martikainen, Miika; Windisch, Marc P; Min, Ji-Young; Bruzzone, Roberto; Aittokallio, Tero; Vaha-Koskela, Markus; Vapalahti, Olli; Pulk, Arto; Velagapudi, Vidya; Kainov, Denis. (2017) Antiviral properties of chemical inhibitors of cellular anti-apoptotic Bcl-2 proteins. Viruses. volum 9 (10).
  Academic article
• Gaelings, Lana; Söderholm, Sandra; Bugai, Andrii; Fu, Yu; Nandania, Jatin; Schepens, Bert; Lorey, Martina B.; Tynell, Janne; Vande Ginste, Liesbeth; Le Goffic, Ronan; Miller, Matthew S.; Kuisma, Marika; Marjomäki, Varpu; De Brabander, Jef; Matikainen, Sampsa; Nyman, Tuula Anneli; Bamford, Dennis H.; Saelens, Xavier; Julkunen, Ilkka; Paavilainen, Henrik; Hukkanen, Veijo; Velagapudi, Vidya; Kainov, Denis. (2017) Regulation of kynurenine biosynthesis during influenza virus infection. The FEBS Journal. volum 284 (2).
  Academic article
• Shim, Jung Min; Kim, Jinhee; Tenson, Tanel; Min, Ji-Young; Kainov, Denis. (2017) Influenza virus infection, interferon response, viral counter-response, and apoptosis. Viruses. volum 9 (8).
  Scientific translation/review

2016

• Anastasina, Maria; Le May, Nicolas; Bugai, Andrii; Fu, Yu; Söderholm, Sandra; Gaelings, Lana; Ohman, Tiina; Tynell, Janne; Kyttänen, Suvi; Barboric, Matjaz; Nyman, Tuula Anneli; Matikainen, Sampsa; Julkunen, Ilkka; Butcher, Sarah J.; Egly, Jean-Marc; Kainov, Denis E.. (2016) Influenza virus NS1 protein binds cellular DNA to block transcription of antiviral genes. Biochimica et Biophysica Acta. Gene Regulatory Mechanisms. volum 1859 (11).
  Academic article
• Söderholm, Sandra; Kainov, Denis E.; Öhman, Tiina; Denisova, Oxana V.; Schepens, Bert; Kulesskiy, Evgeny; Imanishi, Susumu Y.; Corthals, Garry; Hintsanen, Petteri; Aittokallio, Tero; Saelens, Xavier; Matikainen, Sampsa; Nyman, Tuula Anneli. (2016) Phosphoproteomics to characterize host response during influenza a virus infection of human macrophages. Molecular & Cellular Proteomics. volum 15 (10).
  Academic article
• Nyman, Tuula Anneli; Söderholm, Sandra; Kainov, Denis; Ohman, Tiina; Denisova, Oxana V.; Schepens, Bert; Kulesskiy, Evgeny; Imanishi, Susumu Y.; Corthals, Garry; Hintsanen, Petteri; Aittokallio, Tero; Saelens, Xavier; Matikainen, Sampsa. (2016) Phosphoproteomics to Characterize Host Response During Influenza A Virus Infection of Human Macrophages. Molecular & Cellular Proteomics.
  Academic article