Melanie Rae Simpson
+4795443768
Øya helsehus, Øya
About
Positions: Study programme leader at the Office for Medical Education (OME / Enhet for legeutdanning). Associate professor in medican statistics at the Department of Public Health and Nursing.
Qualifications
- Bachelor of Medicine 2008 (Newcastle University, Australia)
- Bachelor of Medical Science 2006 (Newcastle University)
- Masters in Medical Statistics, 2015 (Newcastle University)
- PhD i medicine, 2018 (NTNU - Norwegian University of Science and Technology)
Thesis: Preventing atopic dermatitis with probiotic supplementation - the role of selected breast milk components: The Probiotics in the Prevention of Allergy among Children in Trondheim (ProPACT) study
Research interests
- Allergy related disease
- Prevention
- Immunological components of breast milk
- Breastfeeding
- Clinical trials
Research
Ongoing research:
My current research involves a combination of epidemiological, clinical and translational studies investigating the prevention of allergy related diseases. I primarily work with data from the Prevention of Allergy among Children in Trondheim (PACT) study, and the associated substudies. I am also involved research into the immunological components of breast milk, and how these contribute to the development of the microbiota, gastrointestinal system and immune system of newborn infants.
Probtiotics in the Prevention of Allergy among Children in Trondheim (ProPACT) Study
>The ProPACT study is a randomised, placebo contolled study which investigated the use of probiotic supplementation given to women during the last 4 weeks of pregnancy until 3 months after birth. At 2 years of age, we observed that women born to mothers in the probiotic group had a 40 % reduction in the cumulative incidence of eczema. The biological mechanisms behind this preventive effect are incompletely understood. We are using samples collected during the ProPACT study to investigate these biological mechanisms from different angles.
The ProPACT Study is a substudy of the larger population intervention study (PACT) which aimed to reduce childhood allergy related diseases through reducing environmental smoke and damp/mold exposure and increasing fish consumption during pregnancy and early infancy.
Publications
2023
-
Ahlberg, Emelie;
Al-Kaabawi, Ahmed;
Thune, Rebecka;
Simpson, Melanie Rae;
Pedersen, Sindre Andre;
Cione, Erika;
Jenmalm, Maria Christina;
Tingö, Lina.
(2023)
Breast milk microRNAs: Potential players in oral tolerance development.
Frontiers in Immunology.
volum 14.
Academic literature review
-
Cheung, Ka Yan;
Petrou, Loukia;
Helfer, Bartosz;
Porubayeva, Erika;
Dolgikh, Elena;
Ali, Sana;
Ali, Insaf;
Archibald-Durham, Lindsay;
Brockway, Meredith Merilee;
Bugaeva, Polina;
Chooniedass, Rishma;
Comberiati, Pasquale;
Cortés-Macías, Erika;
D'Elios, Sofia;
Feketea, Gavriela;
Hsu, Peter;
Kana, Musa Abubakar;
Kriulina, Tatiana;
Kunii, Yuzuka.
(2023)
Health and nutrition claims for infant formula: international cross sectional survey.
BMJ. British Medical Journal.
volum 380.
Academic article
-
Golubovic, Jelena;
Baker, Felicity;
Simpson, Melanie Rae;
Neerland, Bjørn Erik.
(2023)
Live and recorded music interventions for management of delirium symptoms in acute geriatric patients: Protocol for a randomized feasibility trial.
Nordic journal of music therapy.
Academic article
-
Haugen, Tina;
Halvorsen, Joar Øveraas;
Friborg, Oddgeir;
Simpson, Melanie Rae;
Mork, Paul Jarle;
Mikkelsen, Gustav;
Elklit, Ask;
Rothbaum, Barbara O.;
Schei, Berit;
Hagemann, Cecilie Therese.
(2023)
Modified prolonged exposure therapy as Early Intervention after Rape (The EIR-study): study protocol for a multicenter randomized add-on superiority trial.
Trials.
volum 24 (1).
Academic article
2022
-
Aukan, Marthe Isaksen;
Coutinho, Silvia;
Pedersen, Sindre Andre;
Simpson, Melanie Rae;
Martins, Catia.
(2022)
Differences in gastrointestinal hormones and appetite ratings between individuals with and without obesity—A systematic review and meta-analysis.
Obesity Reviews.
volum 24 (2).
Academic literature review
-
Gamirova, Aysylu;
Berbenyuk, Anna;
Levina, Daria;
Peshko, Dmitrii;
Simpson, Melanie Rae;
Azad, Meghan B.;
Järvinen, Kirsi M.;
Brough, Helen A.;
Genuneit, Jon;
Greenhawt, Matthew;
Verhasselt, Valerie;
Peroni, Diego G.;
Perkin, Michael R.;
Warner, John O.;
Palmer, Debra J.;
Boyle, Robert J.;
Munblit, Daniel.
(2022)
Food Proteins in Human Breast Milk and Probability of IgE-Mediated Allergic Reaction in Children During Breastfeeding: A Systematic Review.
Journal of Allergy and Clinical Immunology: In Practice.
volum 10 (5).
Academic article
-
Løset, Mari;
Thomas, Laurent Francois;
Brumpton, Ben Michael;
Modalsli, Ellen Heilmann;
Gabrielsen, Maiken Elvestad;
Solvin, Åshild Øksnevad;
Saunes, Marit;
Willer, Cristen;
Åsvold, Bjørn Olav;
Hveem, Kristian;
Dand, Nick;
Tsoi, Lam C;
Nair, Rajan P.;
Smith, Catherine;
Barker, Jonathan N;
Simpson, Melanie Rae;
Elder, James E.;
The International Psoriasis, Gwas Consortium.
(2022)
Discovering novel genes and causal relationships for psoriasis: The HUNT study.
Acta Dermato-Venereologica.
Abstract
-
Mehta, Shriya;
Allen, Hilary I.;
Campbell, Dianne E.;
Arntsen, Karoline Fagerli;
Simpson, Melanie Rae;
Boyle, Robert J..
(2022)
Trends in use of specialized formula for managing cow's milk allergy in young children.
Clinical and Experimental Allergy.
volum 52 (7).
Academic article
-
Neerland, Bjørn Erik;
Busund, Rolf;
Haaverstad, Rune;
Helbostad, Jorunn L.;
Landsverk, Svein A.;
Martinaityte, Ieva;
Norum, Hilde Margrethe;
Ræder, Johan;
Selbæk, Geir;
Simpson, Melanie Rae;
Skaar, Elisabeth;
Skjaervold, Nils Kristian;
Skovlund, Eva;
Slooter, Arjen J. C.;
Svendsen, Øyvind Sverre;
Tønnessen, Theis;
Wahba, Alexander;
Zetterberg, Henrik;
Wyller, Torgeir Bruun.
(2022)
Alpha-2-adrenergic receptor agonists for the prevention of delirium and cognitive decline after open heart surgery (ALPHA2PREVENT): protocol for a multicentre randomised controlled trial.
BMJ Open.
volum 12 (6).
Article
-
Pettersen, Henrik P Sahlin;
Belevich, Ilya;
Røyset, Elin Synnøve;
Smistad, Erik;
Simpson, Melanie Rae;
Jokitalo, Eija;
Reinertsen, Ingerid;
Bakke, Ingunn;
Pedersen, André.
(2022)
Code-Free Development and Deployment of Deep Segmentation Models for Digital Pathology.
Frontiers in medicine.
volum 8.
Academic article
-
Rosvold, Elin Olaug;
Dahl, Christen Peder;
Simpson, Melanie Rae;
Wiker, Harald Gotten.
(2022)
Fastlegevikar uten LIS1 er feil bruk av nye leger.
Dagens medisin.
Feature article
-
Simmonds, Emily Grace;
Adjei, Kwaku Peprah;
Andersen, Christoffer Wold;
Aspheim, Janne Cathrin Hetle;
Battistin, Claudia;
Bulso, Nicola;
Christensen, Hannah M.;
Cretois, Benjamin;
Cubero, Ryan John Abat;
Davidovich, Ivan Andres;
Dickel, Lisa;
Dunn, Benjamin Adric;
Dunn-Sigouin, Etienne;
Dyrstad, Karin;
Einum, Sigurd;
Giglio, Donata;
Gjerløw, Haakon;
Godefroidt, Amélie;
González-Gil, Ricardo.
(2022)
Insights into the quantification and reporting of model-related uncertainty across different disciplines.
iScience.
volum 25.
Academic article
2021
-
Ekelund, Louise;
Gloppen, Inga;
Øien, Torbjørn;
Simpson, Melanie Rae.
(2021)
Duration of breastfeeding, age at introduction of complementary foods and allergy-related diseases: a prospective cohort study.
International Breastfeeding Journal.
Academic article
-
Kallestad, Håvard;
Saksvik, Simen Berg;
Vedaa, Øystein;
Langsrud, Knut;
Morken, Gunnar;
Lydersen, Stian;
Simpson, Melanie Rae;
Dørheim, Signe Karen;
Holmøy, Bjørn;
Germans Selvik, Sara;
Hagen, Kristen;
Stiles, Tore C;
Harvey, Allison G.;
Ritterband, Lee M.;
Sivertsen, Børge;
Scott, Jan.
(2021)
Digital cognitive-behavioural therapy for insomnia compared with digital patient education about insomnia in individuals referred to secondary mental health services in Norway: Protocol for a multicentre randomised controlled trial.
BMJ Open.
volum 11:e050661 (6).
Academic article
-
O'Reilly, Daniel;
Dorodnykh, Denis;
Avdeenko, Nina V.;
Nekliudov, Nikita A.;
Garssen, Johan;
Elolimy, Ahmed A.;
Petrou, Loukia;
Simpson, Melanie Rae;
Yeruva, Laxmi;
Munblit, Daniel.
(2021)
Reply to J Zempleni.
Advances in Nutrition.
volum 12 (1).
Academic article
-
Schei, Kasper;
Simpson, Melanie Rae;
Øien, Torbjørn;
Salamati, Saideh;
Rudi, Knut;
Ødegård, Rønnaug.
(2021)
Allergy-related diseases and early gut fungal and bacterial microbiota abundances in children.
Clinical and Translational Allergy.
volum 11 (5).
Academic article
-
Tingö, Lina;
Ahlberg, Emelie;
Johansson, Lovisa;
Pedersen, Sindre Andre;
Chawla, Konika;
Sætrom, Pål;
Cione, Erika;
Simpson, Melanie Rae.
(2021)
Non-coding RNAs in human breast milk: A systematic review.
Frontiers in Immunology.
volum 12:725323.
Academic literature review
-
Vestergaard, Cecilie Lund;
Vedaa, Øystein;
Simpson, Melanie Rae;
Faaland, Patrick;
Vethe, Daniel;
Kjørstad, Kaia;
Langsrud, Knut;
Ritterband, Lee M;
Sivertsen, Børge;
Stiles, Tore C;
Scott, Jan;
Kallestad, Håvard.
(2021)
The effect of sleep-wake intraindividual variability in digital cognitive behavioral therapy for insomnia: a mediation analysis of a large-scale RCT.
Sleep.
volum 44 (10).
Academic article
2020
-
O'Reilly, Daniel;
Dorodnykh, Denis;
Avdeenko, Nina;
Nekliudov, Nikita A.;
Garssen, Johan;
Elolimy, Ahmed;
Petrou, Loukia;
Simpson, Melanie Rae;
Yeruva, Laxmi;
Munblit, Daniel.
(2020)
Perspective: The Role of Human Breast-Milk Extracellular Vesicles in Child Health and Disease.
Advances in Nutrition.
Academic literature review
-
Schei, Kasper;
Simpson, Melanie Rae;
Avershina, Ekaterina;
Rudi, Knut;
Øien, Torbjørn;
Juliusson, Petur Benedikt;
Underhill, David;
Salamati, Saideh;
Ødegård, Rønnaug.
(2020)
Early gut fungal and bacterial microbiota and childhood growth.
Frontiers in pediatrics.
volum 8.
Academic article
2019
-
Blyuss, Oleg;
Cheung, Ka Yan;
Chen, Jessica;
Parr, Callum;
Petrou, Loukia;
Komarova, Alina;
Kokina, Maria;
Luzan, Polina;
Pasko, Egor;
Eremeeva, Alina;
Peshko, Dmitrii;
Eliseev, Vladimir I;
Pedersen, Sindre Andre;
Azad, Meghan B;
Jarvinen, Kirsi M;
Peroni, Diego G;
Verhasselt, Valerie;
Boyle, Robert J;
Warner, John O.
(2019)
Statistical approaches in the studies assessing associations between human milk immune composition and allergic diseases: A scoping review.
Nutrients.
volum 11 (10).
Academic article
-
Øien, Torbjørn;
Schjelvaag, Astrid;
Storrø, Ola;
Johnsen, Roar;
Simpson, Melanie Rae.
(2019)
Fish Consumption at One Year of Age Reduces the Risk of Eczema, Asthma and Wheeze at Six Years of Age.
Nutrients.
volum 11 (9).
Academic article
2018
-
Avershina, Ekaterina;
Angell, Inga Leena;
Simpson, Melanie Rae;
Storrø, Ola;
Øien, Torbjørn;
Johnsen, Roar;
Rudi, Knut.
(2018)
Low maternal microbiota sharing across gut, breast milk and vagina, as revealed by 16s rRNA gene and reduced metagenomic sequencing.
Genes.
volum 9:231 (5).
Academic article
2017
-
Avershina, Ekaterina;
Slangsvold, Silje;
Simpson, Melanie Rae;
Storrø, Ola;
Johnsen, Roar;
Øien, Torbjørn;
Rudi, Knut.
(2017)
Diversity of vaginal microbiota increases by the time of labor onset.
Scientific Reports.
volum 7 (1).
Academic article
-
Rø, Anne Dorthea;
Simpson, Melanie Rae;
Rø, Torstein Baade;
Storrø, Ola;
Johnsen, Roar;
Videm, Vibeke;
Øien, Torbjørn.
(2017)
Reduced Th22 cell proportion and prevention of atopic dermatitis in infants following maternal probiotic supplementation.
Clinical and Experimental Allergy.
volum 47 (8).
Academic article
-
Simpson, Melanie Rae;
Avershina, Ekaterina;
Storrø, Ola;
Johnsen, Roar;
Rudi, Knut;
Øien, Torbjørn.
(2017)
Breastfeeding associated microbiota in human milk following supplementation with Lactobacillus rhamnosus GG, Lactobacillus acidophilus La-5 and Bifidobacterium animalis subspecies lactis Bb-12.
Journal of Dairy Science (JDS).
volum 101 (2).
Academic article
2016
-
Simpson, Melanie Rae.
(2016)
Systems biology: Impressions from a newcomer graduate student in 2016.
Advances in Physiology Education.
volum 40 (4).
Academic article
-
Simpson, Melanie Rae;
Rø, Anne Dorthea;
Grimstad, Øystein;
Johnsen, Roar;
Storrø, Ola;
Øien, Torbjørn.
(2016)
Atopic dermatitis prevention in children following maternal probiotic supplementation does not appear to be mediated by breast milk TSLP or TGF-β.
Clinical and Translational Allergy.
volum 6 (27).
Academic article
-
Simpson, Melanie Rae;
Øien, Torbjørn.
(2016)
Probiotiske bakterier i forebygging av atopisk dermatitt.
Hud og Helse.
Popular scientific article
-
Simpson, Melanie Rae;
Øien, Torbjørn.
(2016)
Probiotiske bakterier i forebygging av atopisk dermatitt.
BestPractice Dermatologi.
Article
2015
-
Dotterud, Christian;
Avershina, Ekaterina;
Sekelja, Monika;
Simpson, Melanie Rae;
Rudi, Knut;
Storrø, Ola;
Johnsen, Roar;
Øien, Torbjørn.
(2015)
Does maternal perinatal probiotic supplementation alter the intestinal microbiota of mother and child?.
Journal of Pediatric Gastroenterology and Nutrition - JPGN.
volum 61 (2).
Academic article
-
Simpson, Melanie Rae;
Brede, Gaute;
Johansen, Jostein;
Johnsen, Roar;
Storrø, Ola;
Sætrom, Pål;
Øien, Torbjørn.
(2015)
Human breast milk miRNA, maternal probiotic supplementation and atopic dermatitis in offspring.
PLOS ONE.
volum 10:e0143496 (12).
Academic article
-
Simpson, Melanie Rae;
Dotterud, Christian Kvikne;
Storrø, Ola;
Johnsen, Roar;
Øien, Torbjørn.
(2015)
Perinatal probiotic supplementation in the prevention of allergy related disease: 6 year follow up of a randomised controlled trial.
BMC Dermatology.
volum 15 (13).
Academic article
2014
-
Rø, Anne Dorthea;
Simpson, Melanie Rae;
Storrø, Ola;
Johnsen, Roar;
Videm, Vibeke;
Øien, Torbjørn.
(2014)
The predictive value of allergen skin prick tests and IgE tests at pre-school age: The PACT study.
Pediatric Allergy and Immunology.
volum 25 (7).
Academic article
2013
-
Dotterud, Christian Kvikne;
Storrø, Ola;
Simpson, Melanie Rae;
Johnsen, Roar;
Øien, Torbjørn.
(2013)
The impact of pre- and postnatal exposures on allergy related diseases in childhood: a controlled multicentre intervention study in primary health care.
BMC Public Health.
volum 13.
Academic article
Journal publications
-
Ahlberg, Emelie;
Al-Kaabawi, Ahmed;
Thune, Rebecka;
Simpson, Melanie Rae;
Pedersen, Sindre Andre;
Cione, Erika;
Jenmalm, Maria Christina;
Tingö, Lina.
(2023)
Breast milk microRNAs: Potential players in oral tolerance development.
Frontiers in Immunology.
volum 14.
Academic literature review
-
Cheung, Ka Yan;
Petrou, Loukia;
Helfer, Bartosz;
Porubayeva, Erika;
Dolgikh, Elena;
Ali, Sana;
Ali, Insaf;
Archibald-Durham, Lindsay;
Brockway, Meredith Merilee;
Bugaeva, Polina;
Chooniedass, Rishma;
Comberiati, Pasquale;
Cortés-Macías, Erika;
D'Elios, Sofia;
Feketea, Gavriela;
Hsu, Peter;
Kana, Musa Abubakar;
Kriulina, Tatiana;
Kunii, Yuzuka.
(2023)
Health and nutrition claims for infant formula: international cross sectional survey.
BMJ. British Medical Journal.
volum 380.
Academic article
-
Golubovic, Jelena;
Baker, Felicity;
Simpson, Melanie Rae;
Neerland, Bjørn Erik.
(2023)
Live and recorded music interventions for management of delirium symptoms in acute geriatric patients: Protocol for a randomized feasibility trial.
Nordic journal of music therapy.
Academic article
-
Haugen, Tina;
Halvorsen, Joar Øveraas;
Friborg, Oddgeir;
Simpson, Melanie Rae;
Mork, Paul Jarle;
Mikkelsen, Gustav;
Elklit, Ask;
Rothbaum, Barbara O.;
Schei, Berit;
Hagemann, Cecilie Therese.
(2023)
Modified prolonged exposure therapy as Early Intervention after Rape (The EIR-study): study protocol for a multicenter randomized add-on superiority trial.
Trials.
volum 24 (1).
Academic article
-
Aukan, Marthe Isaksen;
Coutinho, Silvia;
Pedersen, Sindre Andre;
Simpson, Melanie Rae;
Martins, Catia.
(2022)
Differences in gastrointestinal hormones and appetite ratings between individuals with and without obesity—A systematic review and meta-analysis.
Obesity Reviews.
volum 24 (2).
Academic literature review
-
Gamirova, Aysylu;
Berbenyuk, Anna;
Levina, Daria;
Peshko, Dmitrii;
Simpson, Melanie Rae;
Azad, Meghan B.;
Järvinen, Kirsi M.;
Brough, Helen A.;
Genuneit, Jon;
Greenhawt, Matthew;
Verhasselt, Valerie;
Peroni, Diego G.;
Perkin, Michael R.;
Warner, John O.;
Palmer, Debra J.;
Boyle, Robert J.;
Munblit, Daniel.
(2022)
Food Proteins in Human Breast Milk and Probability of IgE-Mediated Allergic Reaction in Children During Breastfeeding: A Systematic Review.
Journal of Allergy and Clinical Immunology: In Practice.
volum 10 (5).
Academic article
-
Løset, Mari;
Thomas, Laurent Francois;
Brumpton, Ben Michael;
Modalsli, Ellen Heilmann;
Gabrielsen, Maiken Elvestad;
Solvin, Åshild Øksnevad;
Saunes, Marit;
Willer, Cristen;
Åsvold, Bjørn Olav;
Hveem, Kristian;
Dand, Nick;
Tsoi, Lam C;
Nair, Rajan P.;
Smith, Catherine;
Barker, Jonathan N;
Simpson, Melanie Rae;
Elder, James E.;
The International Psoriasis, Gwas Consortium.
(2022)
Discovering novel genes and causal relationships for psoriasis: The HUNT study.
Acta Dermato-Venereologica.
Abstract
-
Mehta, Shriya;
Allen, Hilary I.;
Campbell, Dianne E.;
Arntsen, Karoline Fagerli;
Simpson, Melanie Rae;
Boyle, Robert J..
(2022)
Trends in use of specialized formula for managing cow's milk allergy in young children.
Clinical and Experimental Allergy.
volum 52 (7).
Academic article
-
Neerland, Bjørn Erik;
Busund, Rolf;
Haaverstad, Rune;
Helbostad, Jorunn L.;
Landsverk, Svein A.;
Martinaityte, Ieva;
Norum, Hilde Margrethe;
Ræder, Johan;
Selbæk, Geir;
Simpson, Melanie Rae;
Skaar, Elisabeth;
Skjaervold, Nils Kristian;
Skovlund, Eva;
Slooter, Arjen J. C.;
Svendsen, Øyvind Sverre;
Tønnessen, Theis;
Wahba, Alexander;
Zetterberg, Henrik;
Wyller, Torgeir Bruun.
(2022)
Alpha-2-adrenergic receptor agonists for the prevention of delirium and cognitive decline after open heart surgery (ALPHA2PREVENT): protocol for a multicentre randomised controlled trial.
BMJ Open.
volum 12 (6).
Article
-
Pettersen, Henrik P Sahlin;
Belevich, Ilya;
Røyset, Elin Synnøve;
Smistad, Erik;
Simpson, Melanie Rae;
Jokitalo, Eija;
Reinertsen, Ingerid;
Bakke, Ingunn;
Pedersen, André.
(2022)
Code-Free Development and Deployment of Deep Segmentation Models for Digital Pathology.
Frontiers in medicine.
volum 8.
Academic article
-
Rosvold, Elin Olaug;
Dahl, Christen Peder;
Simpson, Melanie Rae;
Wiker, Harald Gotten.
(2022)
Fastlegevikar uten LIS1 er feil bruk av nye leger.
Dagens medisin.
Feature article
-
Simmonds, Emily Grace;
Adjei, Kwaku Peprah;
Andersen, Christoffer Wold;
Aspheim, Janne Cathrin Hetle;
Battistin, Claudia;
Bulso, Nicola;
Christensen, Hannah M.;
Cretois, Benjamin;
Cubero, Ryan John Abat;
Davidovich, Ivan Andres;
Dickel, Lisa;
Dunn, Benjamin Adric;
Dunn-Sigouin, Etienne;
Dyrstad, Karin;
Einum, Sigurd;
Giglio, Donata;
Gjerløw, Haakon;
Godefroidt, Amélie;
González-Gil, Ricardo.
(2022)
Insights into the quantification and reporting of model-related uncertainty across different disciplines.
iScience.
volum 25.
Academic article
-
Ekelund, Louise;
Gloppen, Inga;
Øien, Torbjørn;
Simpson, Melanie Rae.
(2021)
Duration of breastfeeding, age at introduction of complementary foods and allergy-related diseases: a prospective cohort study.
International Breastfeeding Journal.
Academic article
-
Kallestad, Håvard;
Saksvik, Simen Berg;
Vedaa, Øystein;
Langsrud, Knut;
Morken, Gunnar;
Lydersen, Stian;
Simpson, Melanie Rae;
Dørheim, Signe Karen;
Holmøy, Bjørn;
Germans Selvik, Sara;
Hagen, Kristen;
Stiles, Tore C;
Harvey, Allison G.;
Ritterband, Lee M.;
Sivertsen, Børge;
Scott, Jan.
(2021)
Digital cognitive-behavioural therapy for insomnia compared with digital patient education about insomnia in individuals referred to secondary mental health services in Norway: Protocol for a multicentre randomised controlled trial.
BMJ Open.
volum 11:e050661 (6).
Academic article
-
O'Reilly, Daniel;
Dorodnykh, Denis;
Avdeenko, Nina V.;
Nekliudov, Nikita A.;
Garssen, Johan;
Elolimy, Ahmed A.;
Petrou, Loukia;
Simpson, Melanie Rae;
Yeruva, Laxmi;
Munblit, Daniel.
(2021)
Reply to J Zempleni.
Advances in Nutrition.
volum 12 (1).
Academic article
-
Schei, Kasper;
Simpson, Melanie Rae;
Øien, Torbjørn;
Salamati, Saideh;
Rudi, Knut;
Ødegård, Rønnaug.
(2021)
Allergy-related diseases and early gut fungal and bacterial microbiota abundances in children.
Clinical and Translational Allergy.
volum 11 (5).
Academic article
-
Tingö, Lina;
Ahlberg, Emelie;
Johansson, Lovisa;
Pedersen, Sindre Andre;
Chawla, Konika;
Sætrom, Pål;
Cione, Erika;
Simpson, Melanie Rae.
(2021)
Non-coding RNAs in human breast milk: A systematic review.
Frontiers in Immunology.
volum 12:725323.
Academic literature review
-
Vestergaard, Cecilie Lund;
Vedaa, Øystein;
Simpson, Melanie Rae;
Faaland, Patrick;
Vethe, Daniel;
Kjørstad, Kaia;
Langsrud, Knut;
Ritterband, Lee M;
Sivertsen, Børge;
Stiles, Tore C;
Scott, Jan;
Kallestad, Håvard.
(2021)
The effect of sleep-wake intraindividual variability in digital cognitive behavioral therapy for insomnia: a mediation analysis of a large-scale RCT.
Sleep.
volum 44 (10).
Academic article
-
O'Reilly, Daniel;
Dorodnykh, Denis;
Avdeenko, Nina;
Nekliudov, Nikita A.;
Garssen, Johan;
Elolimy, Ahmed;
Petrou, Loukia;
Simpson, Melanie Rae;
Yeruva, Laxmi;
Munblit, Daniel.
(2020)
Perspective: The Role of Human Breast-Milk Extracellular Vesicles in Child Health and Disease.
Advances in Nutrition.
Academic literature review
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Schei, Kasper;
Simpson, Melanie Rae;
Avershina, Ekaterina;
Rudi, Knut;
Øien, Torbjørn;
Juliusson, Petur Benedikt;
Underhill, David;
Salamati, Saideh;
Ødegård, Rønnaug.
(2020)
Early gut fungal and bacterial microbiota and childhood growth.
Frontiers in pediatrics.
volum 8.
Academic article
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Blyuss, Oleg;
Cheung, Ka Yan;
Chen, Jessica;
Parr, Callum;
Petrou, Loukia;
Komarova, Alina;
Kokina, Maria;
Luzan, Polina;
Pasko, Egor;
Eremeeva, Alina;
Peshko, Dmitrii;
Eliseev, Vladimir I;
Pedersen, Sindre Andre;
Azad, Meghan B;
Jarvinen, Kirsi M;
Peroni, Diego G;
Verhasselt, Valerie;
Boyle, Robert J;
Warner, John O.
(2019)
Statistical approaches in the studies assessing associations between human milk immune composition and allergic diseases: A scoping review.
Nutrients.
volum 11 (10).
Academic article
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Øien, Torbjørn;
Schjelvaag, Astrid;
Storrø, Ola;
Johnsen, Roar;
Simpson, Melanie Rae.
(2019)
Fish Consumption at One Year of Age Reduces the Risk of Eczema, Asthma and Wheeze at Six Years of Age.
Nutrients.
volum 11 (9).
Academic article
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Avershina, Ekaterina;
Angell, Inga Leena;
Simpson, Melanie Rae;
Storrø, Ola;
Øien, Torbjørn;
Johnsen, Roar;
Rudi, Knut.
(2018)
Low maternal microbiota sharing across gut, breast milk and vagina, as revealed by 16s rRNA gene and reduced metagenomic sequencing.
Genes.
volum 9:231 (5).
Academic article
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Avershina, Ekaterina;
Slangsvold, Silje;
Simpson, Melanie Rae;
Storrø, Ola;
Johnsen, Roar;
Øien, Torbjørn;
Rudi, Knut.
(2017)
Diversity of vaginal microbiota increases by the time of labor onset.
Scientific Reports.
volum 7 (1).
Academic article
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Rø, Anne Dorthea;
Simpson, Melanie Rae;
Rø, Torstein Baade;
Storrø, Ola;
Johnsen, Roar;
Videm, Vibeke;
Øien, Torbjørn.
(2017)
Reduced Th22 cell proportion and prevention of atopic dermatitis in infants following maternal probiotic supplementation.
Clinical and Experimental Allergy.
volum 47 (8).
Academic article
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Simpson, Melanie Rae;
Avershina, Ekaterina;
Storrø, Ola;
Johnsen, Roar;
Rudi, Knut;
Øien, Torbjørn.
(2017)
Breastfeeding associated microbiota in human milk following supplementation with Lactobacillus rhamnosus GG, Lactobacillus acidophilus La-5 and Bifidobacterium animalis subspecies lactis Bb-12.
Journal of Dairy Science (JDS).
volum 101 (2).
Academic article
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Simpson, Melanie Rae.
(2016)
Systems biology: Impressions from a newcomer graduate student in 2016.
Advances in Physiology Education.
volum 40 (4).
Academic article
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Simpson, Melanie Rae;
Rø, Anne Dorthea;
Grimstad, Øystein;
Johnsen, Roar;
Storrø, Ola;
Øien, Torbjørn.
(2016)
Atopic dermatitis prevention in children following maternal probiotic supplementation does not appear to be mediated by breast milk TSLP or TGF-β.
Clinical and Translational Allergy.
volum 6 (27).
Academic article
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Simpson, Melanie Rae;
Øien, Torbjørn.
(2016)
Probiotiske bakterier i forebygging av atopisk dermatitt.
Hud og Helse.
Popular scientific article
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Simpson, Melanie Rae;
Øien, Torbjørn.
(2016)
Probiotiske bakterier i forebygging av atopisk dermatitt.
BestPractice Dermatologi.
Article
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Dotterud, Christian;
Avershina, Ekaterina;
Sekelja, Monika;
Simpson, Melanie Rae;
Rudi, Knut;
Storrø, Ola;
Johnsen, Roar;
Øien, Torbjørn.
(2015)
Does maternal perinatal probiotic supplementation alter the intestinal microbiota of mother and child?.
Journal of Pediatric Gastroenterology and Nutrition - JPGN.
volum 61 (2).
Academic article
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Simpson, Melanie Rae;
Brede, Gaute;
Johansen, Jostein;
Johnsen, Roar;
Storrø, Ola;
Sætrom, Pål;
Øien, Torbjørn.
(2015)
Human breast milk miRNA, maternal probiotic supplementation and atopic dermatitis in offspring.
PLOS ONE.
volum 10:e0143496 (12).
Academic article
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Simpson, Melanie Rae;
Dotterud, Christian Kvikne;
Storrø, Ola;
Johnsen, Roar;
Øien, Torbjørn.
(2015)
Perinatal probiotic supplementation in the prevention of allergy related disease: 6 year follow up of a randomised controlled trial.
BMC Dermatology.
volum 15 (13).
Academic article
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Rø, Anne Dorthea;
Simpson, Melanie Rae;
Storrø, Ola;
Johnsen, Roar;
Videm, Vibeke;
Øien, Torbjørn.
(2014)
The predictive value of allergen skin prick tests and IgE tests at pre-school age: The PACT study.
Pediatric Allergy and Immunology.
volum 25 (7).
Academic article
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Dotterud, Christian Kvikne;
Storrø, Ola;
Simpson, Melanie Rae;
Johnsen, Roar;
Øien, Torbjørn.
(2013)
The impact of pre- and postnatal exposures on allergy related diseases in childhood: a controlled multicentre intervention study in primary health care.
BMC Public Health.
volum 13.
Academic article
Teaching
Courses
Media
2022
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PosterHaugen, Tina; Halvorsen, Joar Øveraas; Hagemann, Cecilie Therese; Schei, Berit; Friborg, Oddgeir; Mork, Paul Jarle; Simpson, Melanie Rae; Mikkelsen, Gustav; Elklit, Ask; Rothbaum, Barbara O.. (2022) Early intervention after rape- poster presentation. Posterwalk Østmarka, St. Olavs hospital . Forskerkurs, Elementær forskningsmetodikk for psykiatri, NTNU; Trondheim. 2022-12-13 - 2022-12-13.
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Academic lectureLøset, Mari; Thomas, Laurent Francois; Brumpton, Ben Michael; Modalsli, Ellen Heilmann; Gabrielsen, Maiken Elvestad; Solvin, Åshild Øksnevad; Saunes, Marit; Willer, Cristen; Åsvold, Bjørn Olav; Hveem, Kristian; Dand, Nick; Tsoi, Lam C; Nair, Rajan P.; Smith, Catherine; Barker, Jonathan N; Simpson, Melanie Rae; Elder, James E.; The International Psoriasis, Gwas Consortium. (2022) Discovering novel genes and causal relationships for psoriasis: The HUNT study. 35th Nordic Congres of Dermatology and Venereology . Nordic Dermatology Association; København. 2022-04-19 - 2022-04-22.
2017
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LectureSimpson, Melanie Rae. (2017) Probiotiske bakterier i forebygging av atopisk dermatitt - kunnskap og kunnskapshull. AllergiFrisk . Helsedirektoratet; Oslo. 2017-11-22 - 2017-11-23.
2016
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LectureRø, Anne Dorthea; Øien, Torbjørn; Simpson, Melanie Rae; Rø, Torstein Baade; Storrø, Ola; Johnsen, Roar; Videm, Vibeke; Sølberg, Hilde Margrete Greva. (2016) The proportion of Th22 cells in infants is reduced following maternal probiotic supplementation, and is associated with atopic dermatitis. ESCCA 2016 . European Society of clinical Cell analysis; Edinburgh. 2016-09-11 - 2016-09-14.
2015
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Popular scientific lectureSimpson, Melanie Rae. (2015) Fra mors tarm til barnets hud, er morsmelk et sendebud?. Forsker Grand Prix, regionale finalen 2015 Trondheim . Norske Forskningsrådet; Byscenen, Trondheim. 2015-09-24 - 2015-09-24.
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Programme participationSimpson, Melanie Rae. (2015) Fra mors tarm til barnets hud, er morsmelk et sendebud?. Forsker Grand Prix regonalefinale 2015 Trondheim [TV]. 2015-12-27.
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InterviewSimpson, Melanie Rae. (2015) Intervju angående resultatene publisert i artikkelen: "Perinatal probiotic supplementation in the prevention of allergy related disease: 6 year follow up of a randomised controlled trial". Midt nytt, Dagsrevyen 21 (NRK) [TV]. 2015-09-21.
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Academic lectureSimpson, Melanie Rae; Brede, Gaute; Johansen, Jostein; Storrø, Ola; Johnsen, Roar; Sætrom, Pål; Øien, Torbjørn. (2015) Human breast milk miRNA, maternal probiotic supplementation and atopic dermatitis (oral presentation). 12th International Symposium on Milk Genomics and Human Health . International Milk Genomics Consortium; Sydney. 2015-10-26 - 2015-10-28.
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PosterSimpson, Melanie Rae; Brede, Gaute; Johansen, Jostein; Storrø, Ola; Johnsen, Roar; Sætrom, Pål; Øien, Torbjørn. (2015) Human breast milk miRNA, maternal probiotics supplementation and atopic dermatitis in offspring (poster). 12th International Symposium on Milk Genomics and Human Health . International Milk Genomics Consortium; Sydney. 2015-10-26 - 2015-10-28.
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Academic lectureSimpson, Melanie Rae; Dotterud, Christian; Avershina, Ekaterina; Sekelja, Monika; Rudi, Knut; Storrø, Ola; Johnsen, Roar; Øien, Torbjørn. (2015) Probiotics to mothers - impact on diversity in offspring (oral presentation). Children: Food and the Environment . Children's Environmental Health Network (CEHN); Austin, Texas. 2015-02-04 - 2015-02-06.
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Academic lectureSimpson, Melanie Rae; Øien, Torbjørn; Storrø, Ola; Dotterud, Christian; Johnsen, Roar. (2015) Perinatal probiotics and eczema in school aged children (oral presentation). Children: Food and the Environment . Children's Environmental Health Network (CEHN); Austin, Texas. 2015-02-04 - 2015-02-06.