Oluf Dimitri Røe
About
Appointments and Research Interests
My primary research interests combine clinical and basic cancer research (translational), focusing on biomarkers for early cancer detection, predictive and prognostic biomarkers, genome-wide analyses, and mechanisms of treatment resistance.
We have also developed the HUNT Lung Cancer Model, a tool for predicting lung cancer risk.
Historically, my research has centered on mesothelioma, an asbestos-related cancer, and more recently expanded to include lung and gastric cancers. I have published studies on serum and tissue biomarkers for mesothelioma and gastric cancer. Specifically, in mesothelioma, my experience includes clinical research where I initiated and completed studies on early detection using pre-clinical serum samples, in collaboration with the Cancer Registry, the Janus Biobank, and the National Centre for Asbestos Related Diseases at the University of Western Australia, Perth. At our research department, we conducted three gene expression studies at the FUGE (Functional Genomics) core facility using Affymetrix U133 Plus 2 and Illumina HumanHT-12 v3 Expression BeadChip platforms on human mesothelioma and normal pleural samples.
In recent years, a collaboration with a leading bioinformatics group headed by Prof. Ioannis Tsamardinos at the University of Crete has resulted in the development of the HUNT Lung Cancer Model, an online calculator, and several new publications.
Read more here.
Since November 2010, I have collaborated as a visiting researcher and supervisor with Nanjing Medical University, China, focusing on mesothelioma, lung, and gastric cancers. This includes work with oncologists at Nanjing Medical University and independent collaborations with Yuyao People’s Hospital (Zhejiang Province, China) and the University of Tokyo, Japan—resulting in one of the first studies linking mesothelioma in women to occupational asbestos exposure in China.
The HUNT Biobank in Levanger, Norway, is one of Scandinavia’s largest biobanks, containing serum and clinical data from approximately 120,000 participants. Since May 2011, I have collaborated with HUNT to discover tumor-specific microRNAs in pre-diagnostic serum. The Cancer-Biomarker-HUNT Project aims to identify serum biomarkers for early detection of lung cancer and mesothelioma.
We developed a validated clinical risk prediction model and online calculator for lung cancer—the HUNT Lung Cancer Model—which, combined with GWAS and pre-diagnostic microRNA data, can refine screening and diagnostic strategies. This initiative is part of the EARLYSCREEN Project.
Currently, we are conducting the E-Lung Study, which aims to develop novel polygenic risk models, compare the HUNT model with PLCOm2012, and create a smoking cessation app for general practitioners.
Since 2013, I have served as Clinical Associate Professor at Aalborg University Hospital, Denmark. Aalborg, the capital of Northern Jutland, hosted Denmark’s only asbestos factory (Eternit), which processed 80% of all asbestos imported into the country. The long-term effects of asbestos use have resulted in an age-standardized incidence rate of mesothelioma in men that is 2–3 times higher in Northern Jutland compared to other Danish regions. We have recently demonstrated the environmental impact on mesothelioma risk in women and, for the first time, identified germline cancer susceptibility genes in mesothelioma in collaboration with the University of Chicago. I currently hold a position as Clinical Associate Professor at the Department of Oncology in Aalborg and have initiated a multidisciplinary group dedicated to mesothelioma research.
Since 2018, I have held a 20% Professorship at the Department of Clinical and Molecular Research, NTNU, Trondheim, Norway, and Levanger Hospital, as well as a position since 2011 as Senior Consultant Oncologist at Levanger Hospital.
Publications
2025
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Pestarino, Luca;
Fortner, Shannon Renee Turzanski;
Nøst, Therese Haugdahl;
Fotopoulos, Ioannis;
Urbarova, Ilona H.;
Røe, Oluf Dimitri.
(2025)
Recommendations for Validating Omics Prediction Models: Insights from a Lung Cancer RNA Biomarker Study.
Cancer Epidemiology, Biomarkers and Prevention
Academic article
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Asphaug, Lars;
Akslen, Lars Andreas;
Blix, Egil Støre;
Boge, Beate;
Borgen, Elin Faye;
Brekke, Marianne B..
(2025)
Cost-Effectiveness of Prosigna for Adjuvant Treatment Decisions in Early Breast Cancer: Healthcare Sector - and Societal Perspectives.
Clinical Breast Cancer
Academic article
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Gisvold, Sven Erik;
Wyller, Torgeir Bruun;
Grøttumsbråten, Janne;
Haug, Lene C.;
Hove, Aud;
Haukelien, Heidi.
(2025)
Helseforetaksmodellen: En ulykke for norsk helsevesen.
Feature article
2024
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Wu, Chen;
Røe, Oluf Dimitri;
Wei, Jia.
(2024)
Editorial: Direct or indirect endocrine and metabolic consequences of malignancies.
Frontiers in Endocrinology
Editorial
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Fotopoulos, Ioannis;
Nguyen, Olav Toai Duc;
Nøst, Therese Haugdahl;
Markaki, Maria;
Lagani, Vincenzo;
Mjelle, Robin.
(2024)
Promising microRNAs in pre-diagnostic serum associated with lung cancer up to eight years before diagnosis: a HUNT study.
Journal of Cancer Research and Clinical Oncology
Academic article
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Ohnstad, Hege Oma;
Blix, Egil Støre;
Akslen, Lars Andreas;
Gilje, Bjørnar;
Raj, Sunil Xavier;
Skjerven, Helle.
(2024)
Impact of Prosigna test on adjuvant treatment decision in lymph node-negative early breast cancer—a prospective national multicentre study (EMIT-1).
ESMO Open
Academic article
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Nguyen, Olav Toai Duc;
Ioannis, Fotopoulos;
Nøst, Therese Haugdahl;
Maria, Markaki;
Vincenzo, Lagani;
Ioannis, Tsamardinos.
(2024)
The HUNT lung-SNP model: genetic variants plus clinical variables improve lung cancer risk assessment over clinical models.
Journal of Cancer Research and Clinical Oncology
Academic article
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Zandwijk, Nico van;
Frank, Arthur L.;
Reid, Glen;
Røe, Oluf Dimitri;
Amos, Christopher I..
(2024)
Asbestos-Related lung Cancer: An underappreciated oncological issue.
Lung Cancer
Academic article
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Nguyen, Olav Toai Duc;
Fotopoulos, Ioannis;
Markaki, Maria;
Tsamardinos, Ioannis;
Lagani, Vincenzo;
Røe, Oluf Dimitri.
(2024)
Improving Lung Cancer Screening Selection: The HUNT Lung Cancer Risk Model for Ever-Smokers Versus the NELSON and 2021 United States Preventive Services Task Force Criteria in the Cohort of Norway: A Population-Based Prospective Study.
JTO Clinical and Research Reports
Academic article
2023
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Andersen, Gøran Troseth;
Zhao, Chun Mei;
Grønbech, Jon Erik;
Chen, Yijiang;
Zayachkivska, Oksana;
Røe, Oluf Dimitri.
(2023)
Clinical aspects in translational research on gastric tumorigenesis and development of new treatments*.
Праці Наукового товариства імені Шевченка. Медичні науки
Academic literature review
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Gisvold, Sven Erik;
Jensen, Bjarne;
Haug, Lene;
Wyller, Torgeir Bruun;
Hove, Aud;
Rangønes, Ingrid Ovidie.
(2023)
Et todelt helsevesen.
Feature article
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Bjerner, Lars;
Bratt, Ola;
Aas, Kirsti;
Albertsen, Peter C.;
Fosså, Sophie D.;
Kvåle, Rune.
(2023)
Baseline Serum Prostate-specific Antigen Value Predicts the Risk of Subsequent Prostate Cancer Death—Results from the Norwegian Prostate Cancer Consortium.
European Urology
Academic article
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Yuce, Tuna Han;
Ak, Guntulu;
Metintas, Selma;
Dundar, Emine;
Røe, Oluf Dimitri;
Panou, Vasiliki.
(2023)
BAP1, Wilms’ tumor 1, and calretinin in predicting survival and response to first-line chemotherapy in patients with pleural mesothelioma.
Journal of Cancer Research and Clinical Oncology
Academic article
2022
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Røe, Oluf Dimitri;
Creaney, Jenette.
(2022)
Response to “Revisiting ‘BAP1ness’ in Malignant Pleural Mesothelioma”.
Journal of Thoracic Oncology
Reader opinion piece
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Dalsgaard, Sofie Bünemann;
Würtz, Else Toft;
Hansen, Johnni;
Røe, Oluf Dimitri;
Omland, Øyvind.
(2022)
Cancer incidence and risk of multiple cancers after environmental asbestos exposure in childhood—a long-term register-based cohort study.
International Journal of Environmental Research and Public Health (IJERPH)
Academic article
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Dalsgaard, Sofie Bünemann;
Würtz, Else Toft;
Hansen, Johnni;
Røe, Oluf Dimitri;
Omland, Øyvind.
(2022)
A Cohort Study on Cancer Incidence among Women Exposed to Environmental Asbestos in Childhood with a Focus on Female Cancers, including Breast Cancer.
International Journal of Environmental Research and Public Health (IJERPH)
Academic article
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Røe, Oluf Dimitri;
Fotopoulos, I;
Nguyen, Olav Toai Duc;
Nøst, Therese Haugdahl;
Markaki, M;
Lagani, Vincenzo.
(2022)
Common MicroRNAs in Pre-diagnostic Serum Associated with Lung Cancer in Two Cohorts up to Eight Years Before Diagnosis: A HUNT Study.
Journal of Thoracic Oncology
Abstract
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Nguyen, Olav Toai Duc;
Fotopoulos, I;
Nøst, Therese Haugdahl;
Markaki, M;
Lagani, Vincenzo;
Tsamardinos, I.
(2022)
Genetic Variants of HUNT Lung Cancer Model Improve Lung Cancer Risk Assessment Over Clinical Models.
Journal of Thoracic Oncology
Abstract
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Louw, Amber;
Panou, Vasiliki;
Szejniuk, Weronika Maria;
Meristoudis, Christos;
Chai, Siaw Ming;
Vliet, Chris van.
(2022)
BAP1 Loss by Immunohistochemistry Predicts Improved Survival to First-Line Platinum and Pemetrexed Chemotherapy for Patients With Pleural Mesothelioma: A Validation Study.
Journal of Thoracic Oncology
Academic article
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Lynggård, Louise Andersen;
Panou, Vasiliki;
Szejniuk, Weronika;
Røe, Oluf Dimitri;
Meristoudis, Christos.
(2022)
Diagnostic capacity of BAP1 and MTAP in cytology from effusions and biopsy in mesothelioma.
Journal of the American Society of Cytopathology (JASC)
Academic article
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Ma, Ling;
Chen, Guosheng;
Wang, Deqiang;
Zhang, Kai;
Zhao, Fengjiao;
Tang, Jie.
(2022)
A nomogram to predict survival probability of gastric cancer patients undergoing radical surgery and adjuvant chemotherapy.
Frontiers in Oncology
Academic article
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Urbarova, Ilona H.;
Nøst, Therese Haugdahl;
Skogholt, Anne Heidi;
Mjelle, Robin;
Paulsen, Erna-Elise;
Dønnem, Tom.
(2022)
Increased Levels of mRNAs and miRNAs Associated with Imminent and Advanced Lung Cancer.
Journal of Thoracic Oncology
Abstract
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Nøst, Therese Haugdahl;
Skogholt, Anne Heidi;
Urbarova, Ilona Halva;
Mjelle, Robin;
Paulsen, Erna-Elise;
Dønnem, Tom.
(2022)
Increased levels of microRNA-320 in blood serum and plasma is associated with imminent and advanced lung cancer.
Molecular Oncology
Academic article
2021
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Jensen, Bjarne;
Haug, Lene;
Gisvold, Sven Erik;
Grøttumsbråten, Janne;
Hove, Aud;
Isumhaugen, Mariann.
(2021)
Farvel til helseforetakene?.
Feature article
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Papoutsoglou, Georgios;
Karaglani, Makrina;
Lagani, Vincenzo;
Thomson, Naomi;
Røe, Oluf Dimitri;
Tsamardinos, Ioannis.
(2021)
Automated machine learning optimizes and accelerates predictive modeling from COVID-19 high throughput datasets.
Scientific Reports
Academic article
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Petersen, Thomas Ringgaard;
Panou, Vasiliki;
Meristoudis, Christos;
Weinreich, Ulla Møller;
Røe, Oluf Dimitri.
(2021)
Clinical prognostic factors in pleural mesothelioma: best supportive care and anti-tumor treatments in a real-life setting.
Acta Oncologica
Academic article
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Szejniuk, Weronika Maria;
Nielsen, Martin Skovmos;
Takács-Szabó, Zsuzsanna;
Pawlowski, Jacek;
Al-Saadi, Sahar Sulaiman;
Maidas, Panagiotis.
(2021)
High-dose thoracic radiation therapy for non-small cell lung cancer: a novel grading scale of radiation-induced lung injury for symptomatic radiation pneumonitis.
Radiation Oncology
Academic article
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Szejniuk, Weronika Maria;
Cekala, M.;
Bøgsted, Martin;
Meristoudis, Christos;
McCulloch, Tine;
Falkmer, Ursula.
(2021)
Adjuvant platinum-based chemotherapy in non-small cell lung cancer: The role of relative dose-intensity and treatment delay.
Cancer Treatment and Research Communications
Academic article
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Wyller, Torgeir Bruun;
Gisvold, Sven Erik;
Grøttumsbråten, Janne;
Haug, Lene;
Hove, Aud;
Isumhaugen, Mariann.
(2021)
Sykehusreformen har skapt mer byråkrati og svekket samarbeidet.
Feature article
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Wyller, Torgeir Bruun;
Gisvold, Sven Erik;
Grøttumsbråten, Janne;
Haug, Lene;
Hove, Aud;
Isumhaugen, Mariann.
(2021)
Sykehusreformen har skapt byråkrati og svekket samarbeidet.
Feature article
2020
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Nguyen, Olav Toai Duc;
Sundstrøm, Stein Harald;
Westvik, Ganna Surzhykova;
Røttereng, Ane Karoline Stræte;
Melhus, Mona Røli;
Bergseth, Cecilie.
(2020)
Major durable response of pembrolizumab in chemotherapy refractory small cell bladder cancer: A case report.
Case Reports in Oncology
Academic article
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Røe, Oluf Dimitri.
(2020)
Democratic and ethical problem of lung cancer screening: Exclusion of true high-risk populations. Can it be fixed? Yes.
BMJ Open Respiratory Research
Academic literature review
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Würtz, Else Toft;
Hansen, Johnni;
Røe, Oluf Dimitri;
Omland, Øyvind.
(2020)
Asbestos exposure and haematological malignancies: a Danish cohort study.
European Journal of Epidemiology (EJE)
Academic article
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Panou, Vasiliki;
Røe, Oluf Dimitri.
(2020)
Inherited Genetic Mutations and Polymorphisms in Malignant Mesothelioma: A Comprehensive Review.
International Journal of Molecular Sciences
Academic literature review
2019
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Røe, Oluf Dimitri;
Markaki, Maria;
Tsamardinos, Ioannis;
Lagani, Vincenzo;
Nguyen, Olav Toai Duc;
Pedersen, Jesper Holst.
(2019)
‘Reduced’ HUNT model outperforms NLST and NELSON study criteria in predicting lung cancer in the Danish screening trial.
BMJ Open Respiratory Research
Academic article
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Szejniuk, Weronika Maria;
Nielsen, Martin Skovmos;
Brønnum, Dorthe;
Takacs-Szabo, Z;
Weinreich, Ulla Møller;
Thomsen, L Pilegaard.
(2019)
Fractional exhaled nitric oxide as a potential biomarker for radiation pneumonitis in patients with non-small cell lung cancer: A pilot study.
Clinical and Translational Radiation Oncology
Academic article
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Lakiotaki, Kleanthi;
Georgakopoulos, George;
Castanas, Elias;
Røe, Oluf Dimitri;
Borboudakis, Giorgos;
Tsamardinos, Ioannis.
(2019)
A data driven approach reveals disease similarity on a molecular level.
npj Systems Biology and Applications
Academic article
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Panou, Vasiliki;
Vyberg, Mogens;
Meristoudis, Christos;
Hansen, Johnni;
Bøgsted, Martin;
Omland, Øyvind.
(2019)
Non-occupational exposure to asbestos is the main cause of malignant mesothelioma in women in North Jutland, Denmark.
Scandinavian Journal of Work, Environment and Health
Academic article
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Dalsgaard, Sofie Bunemann;
Würtz, Else Toft;
Hansen, Johnni;
Røe, Oluf Dimitri;
Omland, Øyvind.
(2019)
Environmental asbestos exposure in childhood and risk of mesothelioma later in life: A long-term follow-up register-based cohort study.
Occupational and Environmental Medicine
Academic article
2018
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Szejniuk, Weronika Maria;
Robles, Ana I.;
McCulloch, Tine;
Falkmer, Ursula;
Røe, Oluf Dimitri.
(2018)
Epigenetic predictive biomarkers for response or outcome to platinum-based chemotherapy in non-small cell lung cancer, current state-of-art.
The Pharmacogenomics Journal
Academic article
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Panou, Vasiliki;
Gadiraju, Meghana;
Wolin, Arthur;
Weipert, Caroline M.;
Skarda, Emily;
Husain, Aliya N..
(2018)
Frequency of germline mutations in cancer susceptibility genes in malignant mesothelioma.
Journal of Clinical Oncology
Academic article
-
Røe, Oluf Dimitri.
(2018)
Mesothelioma diagnosis and prognosis, are we moving beyond histology and performance status towards circulating biomarkers?.
Journal of Thoracic Disease (JTD)
Editorial
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Markaki, Maria Dorothea Haaberg;
Tsamardinos, Ioannis;
Langhammer, Arnulf;
Lagani, Vincenzo;
Hveem, Kristian;
Røe, Oluf Dimitri.
(2018)
A Validated Clinical Risk Prediction Model for Lung Cancer in Smokers of All Ages and Exposure Types: A HUNT Study.
EBioMedicine
Academic article
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Rangul, Vegar;
Sund, Erik Reidar;
Mork, Paul Jarle;
Røe, Oluf Dimitri;
Bauman, Adrian.
(2018)
The associations of sitting time and physical activity on total and site-specific cancer incidence: Results from the HUNT study, Norway.
PLOS ONE
Academic article
2017
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Røe, Oluf Dimitri;
Wahl, Sissel Gyrid Freim.
(2017)
The undifferentiated carcinoma that became a melanoma: Re-biopsy of a cancer of an unknown primary site: a case report.
Journal of Medical Case Reports
Academic article
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Røe, Oluf Dimitri.
(2017)
The High Cost of New Cancer Therapies-A Challenge of Inequality for All Countries.
JAMA Oncology
Academic article
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Wang, Q;
Chen, Q;
Zhu, L;
Chen, M;
Xu, W;
Panday, S.
(2017)
JWA regulates TRAIL-induced apoptosis via MARCH8-mediated DR4 ubiquitination in cisplatin-resistant gastric cancer cells.
Oncogenesis
Academic article
2016
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Li, Qiang;
Zhi, Xiaofei;
Zhou, Jianping;
Tao, Ran;
Zhang, Jiaxuan;
Chen, Peisheng.
(2016)
Circulating tumor cells as a prognostic and predictive marker in gastrointestinal stromal tumors: A prospective study.
OncoTarget
Academic article
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Qian, Jing;
Qian, Yingying;
Wang, Jian;
Gu, Bing;
Pei, Dong;
He, Shaohua.
(2016)
A clinical prognostic scoring system for resectable gastric cancer to predict survival and benefit from paclitaxel- or oxaliplatin-based adjuvant chemotherapy.
Drug Design, Development and Therapy
Academic article
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Qian, Jing;
Zhu, Weiyou;
Wang, Keming;
Ma, Lin;
Xu, Jin;
Xu, Tongpeng.
(2016)
JWA loss promotes cell migration and cytoskeletal rearrangement by affecting HER2 expression and identifies a high-risk subgroup of HER2-positive gastric carcinoma patients.
OncoTarget
Academic article
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Chen, Xiao-Feng;
Qian, Jing;
Pei, Dong;
Zhou, Chen;
Røe, Oluf Dimitri;
Zhu, Fang.
(2016)
Prognostic value of perioperative leukocyte count in resectable gastric cancer.
World Journal of Gastroenterology (WJG)
Academic article
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Zhi, Xiaofei;
Jiang, Baofei;
Yu, Junbo;
Røe, Oluf Dimitri;
Qin, Jun;
Ni, Qingfeng.
(2016)
Prognostic role of microscopically positive margins for primary gastrointestinal stromal tumors: a systematic review and meta-analysis.
Scientific Reports
Academic article
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Robles, Ana I.;
Olsen, Karina Standahl;
Tsui, Dana W.T.;
Georgoulias, Vassilis;
Creaney, Jenette;
Dobra, Katalin.
(2016)
Excerpts from the 1st international NTNU symposium on current and future clinical biomarkers of cancer: innovation and implementation, June 16th and 17th 2016, Trondheim, Norway.
Journal of Translational Medicine
Academic article
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Røe, Oluf Dimitri;
Panou, V.
(2016)
Pemetrexed as first or second line in 112 danish patients.
Journal of Clinical Oncology
Abstract
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Røe, Oluf Dimitri;
Mjelle, Robin;
Sætrom, Pål;
Andreassen, Trygve;
Bathen, Tone Frost;
Hveem, Kristian.
(2016)
Serum microRNAs/enriched pathways in lung cancer 1-4 years before diagnosis: A pilot study from the HUNT Biobank, Norway.
Journal of Clinical Oncology
Abstract
2015
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Zhu, Weiyou;
Røe, Oluf Dimitri;
Wu, Chen;
Li, Wei;
Guo, Renhua;
Gu, Yanhong.
(2015)
Activity of pemetrexed-based regimen as first-line chemotherapy for advanced non-small cell lung cancer with asymptomatic inoperable brain metastasis: A retrospective study.
Journal of chemotherapy
Academic article
-
Røe, Oluf Dimitri;
Stella, Giulia Maria.
(2015)
Malignant pleural mesothelioma: History, controversy and future of a manmade epidemic.
European Respiratory Review
Academic literature review
-
Gao, Zhibin;
Hiroshima, Kenzo;
Wu, Xiaodong;
Zhang, Jixian;
Shao, Dichu;
Shao, Huajiang.
(2015)
Asbestos textile production linked to malignant peritoneal and pleural mesothelioma in women: Analysis of 28 cases in Southeast China.
American Journal of Industrial Medicine
Academic article
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Panou, V;
Vyberg, M;
Weinreich, UM;
Meristoudis, C;
Falkmer, UG;
Røe, Oluf Dimitri.
(2015)
The established and future biomarkers of malignant pleural mesothelioma.
Cancer Treatment Reviews
Academic literature review
-
Røe, Oluf Dimitri;
Wyller, Torgeir Bruun.
(2015)
Hva står på spill med lokalsykehusene? :.
Bioingeniøren
Reader opinion piece
2014
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Chen, Y;
Huang, Y;
Huang, Yulin;
Xia, X;
Zhang, J;
Zhou, Y.
(2014)
JWA suppresses tumor angiogenesis via Sp1-activated matrix metalloproteinase-2 and its prognostic significance in human gastric cancer.
Carcinogenesis
Academic article
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Cao, Hailong;
Zhou, Qing;
Lan, Rongfang;
Røe, Oluf Dimitri;
Chen, Xin;
Chen, Yijiang.
(2014)
A functional polymorphism C-509t in TGF-1 promoter contributes to susceptibility and prognosis of lone atrial fibrillation in chinese population.
PLOS ONE
Academic article
-
Kerkentzes, Konstantinos;
Lagani, Vincenzo;
Tsamardinos, Ioannis;
Vyberg, Mogens;
Røe, Oluf Dimitri.
(2014)
Hidden treasures in "ancient" microarrays: Gene expression portrays biology and potential resistance pathways of major lung cancer subtypes and normal tissue.
Frontiers in Oncology
Academic article
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Cao, Hailong;
Zhu, Jinfu;
Xi, Lei;
Røe, Oluf Dimitri;
Chen, Yijiang;
Wang, Dongjin.
(2014)
Preoperative serum receptor activator of nuclear factor-κB ligand/osteoprotegerin predict stabilization of spontaneously restored sinus rhythm in persistent atrial fibrillation patients after mitral valve surgery.
Cardiology
Academic article
-
Røe, Oluf Dimitri;
Oppegaard, Per Arne;
Revheim, Mona Elisabeth;
Svindland, Aud.
(2014)
Adrenocortical carcinoma mimicking lung cancer and responding to vinorelbine/carboplatin and pemetrexed/carboplatin.
BMJ Case Reports
Academic article
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Xu, W;
Chen, Q;
Wang, Q;
Sun, Y;
Wang, S;
Li, A.
(2014)
JWA reverses cisplatin resistance via the CK2-XRCC1 pathway in human gastric cancer cells.
Cell Death & Disease
Academic article
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Huang, Yefei;
Wang, Weimin;
Chen, Yansu;
Huang, Yulin;
Zhang, Jianbing;
He, Song.
(2014)
The opposite prognostic significance of nuclear and cytoplasmic p21 expression in resectable gastric cancer patients.
Journal of gastroenterology
Academic article
-
Cao, Hailong;
Wu, Ying;
Li, Qingguo;
Wu, Yanhu;
Zhou, Qing;
Røe, Oluf Dimitri.
(2014)
Serum sRANKL/OPG predict recurrence after radiofrequency catheter ablation of lone atrial fibrillation.
International Journal of Cardiology
Academic article
-
Xu, W;
Wang, S;
Chen, Q;
Zhang, Y;
Ni, P;
Wu, X.
(2014)
TXNL1-XRCC1 pathway regulates cisplatin-induced cell death and contributes to resistance in human gastric cancer.
Cell Death & Disease
Academic article
-
Røe, Oluf Dimitri.
(2014)
Postoperative leukopenia is an independent prognostic factor in resectable gastric cancer patients.
Journal of Clinical Oncology
Abstract
-
Chen, X;
Zhu, Q;
Liu, Y;
Liu, P;
Yin, Y;
Guo, R.
(2014)
Icotinib is an active treatment of non-small-cell lung cancer: A retrospective study.
PLOS ONE
Academic article
2013
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Ye, Yang;
Li, Xuan;
Yang, Jiangjing;
Miao, Shuhan;
Wang, Shouyu;
Chen, Yansu.
(2013)
MDM2 is a useful prognostic biomarker for resectable gastric cancer.
Cancer Science
Academic article
-
Cao, HaiLong;
Li, Qingguo;
Li, Mingna;
Røe, Oluf Dimitri;
Wu, Zhong;
Zhou, Qing.
(2013)
Osteoprotegerin/RANK/RANKL axis and atrial remodeling in mitral valvular patients with atrial fibrillation.
International Journal of Cardiology
Academic article
-
Chen, Xiaofeng;
Liu, YQ;
Røe, Oluf Dimitri;
Qian, YY;
Guo, RH;
Zhu, LJ.
(2013)
Gefitinib or Erlotinib as Maintenance Therapy in Patients with Advanced Stage Non-Small Cell Lung Cancer: A Systematic Review.
PLOS ONE
Academic article
-
Xu, CH;
Wu, C;
Xia, Y;
Zhong, ZP;
Liu, Xiang;
Xu, Jing.
(2013)
WT1 Promotes Cell Proliferation in Non-Small Cell Lung Cancer Cell Lines Through Up-Regulating Cyclin D1 and p-pRb In Vitro and In Vivo.
PLOS ONE
Academic article
-
Cao, Hailong;
Zhou, Qing;
Wu, Yanhu;
Li, Qingguo;
Røe, Oluf Dimitri;
Chen, Yijiang.
(2013)
Preoperative serum soluble receptor activator of nuclear factor-kappa B ligand and osteoprotegerin predict postoperative atrial fibrillation in patients undergoing cardiac valve surgery.
Annals of Thoracic Surgery
Academic article
-
Røe, Oluf Dimitri.
(2013)
DNA repair suppression and effect of cisplatin in mesothelioma and lung cancer cell lines.
Journal of Clinical Oncology
Abstract
-
Chen, Yansu;
Xia, Xiaowei;
Wang, Shouyu;
Wu, Xuming;
Zhang, Jianbing;
Zhou, Yan.
(2013)
High FAK combined with low JWA expression: clinical prognostic and predictive role for adjuvant fluorouracil-leucovorin-oxaliplatin treatment in resectable gastric cancer patients.
Journal of gastroenterology
Academic article
-
Xi, Lei;
Cao, HaiLong;
Zhu, Jinfu;
Røe, Oluf Dimitri;
Li, Mingna;
Wu, Yanhu.
(2013)
OPG/RANK/RANKL Axis in Stabilization of Spontaneously Restored Sinus Rhythm in Permanent Atrial Fibrillation Patients after Mitral Valve Surgery.
Cardiology
Academic article
-
Chen, Xiaofeng;
Zha, Xiaoming;
Chen, Wei;
Zhu, Tingting;
Qiu, Jinrong;
Røe, Oluf Dimitri.
(2013)
Leptin attenuates the anti-estrogen effect of tamoxifen in breast cancer.
Biomedicine & Pharmacotherapy
Academic article
-
Wang, Shouyu;
Wu, Xuming;
Zhang, Jianbing;
Chen, Yansu;
Xu, Jin;
Xia, Xiaowei.
(2013)
CHIP functions as a novel suppressor of tumour angiogenesis with prognostic significance in human gastric cancer.
Gut
Academic article
2012
-
Tsamardinos, I;
Borboudakis, G;
Christodoulou, EG;
Røe, Oluf Dimitri.
(2012)
Chemosensitivity Prediction of Tumours Based on Expression, miRNA, and Proteomics Data.
International Journal of Systems Biology and Biomedical Technologies
Academic article
-
Røe, Oluf Dimitri;
Szulkin, Adam;
Anderssen, Endre;
Flatberg, Arnar;
Sandeck, Helmut;
Amundsen, Tore.
(2012)
Molecular Resistance Fingerprint of Pemetrexed and Platinum in a Long-Term Survivor of Mesothelioma.
PLOS ONE
Academic article
-
Chen, X.-F.;
Wang, R;
Yin, YM;
Røe, Oluf Dimitri;
Li, J;
Zhu, LJ.
(2012)
The effect of monosialotetrahexosylganglioside (GM1) in prevention of oxaliplatin induced neurotoxicity: A retrospective study.
Biomedicine & Pharmacotherapy
Academic article
-
Wang, SY;
Wu, XM;
Chen, YS;
Zhang, JB;
Ding, JJ;
Zhou, Yan.
(2012)
Prognostic and Predictive Role of JWA and XRCC1 Expressions in Gastric Cancer.
Clinical Cancer Research
Academic article
-
Chen, Xiaofeng;
Liu, YQ;
Yin, YM;
Jin, S;
Ping, GQ;
Røe, Oluf Dimitri.
(2012)
Recombinant human endostatin (endostar) decreased recurrent ascites, pleural fluid and ascitic VEGF in a case of advanced mesothelioma.
Journal of chemotherapy
Academic article
-
Liu, Xin;
Wang, Shouyu;
Xia, Xiaowei;
Chen, Yansu;
Zhou, Yan;
Wu, Xuming.
(2012)
Synergistic Role between p53 and JWA: Prognostic and Predictive Biomarkers in Gastric Cancer.
PLOS ONE
Academic article
2011
-
Cao, HaiLong;
Wang, Jian;
Xi, Lei;
Røe, Oluf Dimitri;
Chen, Yijiang;
Wang, Dongjin.
(2011)
Dysregulated Atrial Gene Expression of Osteoprotegerin/Receptor Activator of Nuclear Factor-kappa B (RANK)/RANK Ligand Axis in the Development and Progression of Atrial Fibrillation.
Circulation Journal
Academic article
2010
-
Sandeck, Helmut;
Røe, Oluf Dimitri;
Kjærheim, Kristina;
Willèn, Helena;
Larsson, Erik.
(2010)
Re-evaluation of histological diagnoses of malignant mesothelioma by immunohistochemistry.
Diagnostic Pathology
Academic article
-
Røe, Oluf Dimitri;
Anderssen, Endre;
Sandeck, Helmut;
Christensen, Tone;
Larsson, Erik;
Lundgren, Steinar.
(2010)
Malignant pleural mesothelioma: Genome-wide expression patterns reflectinggeneral resistance mechanisms and a proposal of novel targets.
Lung Cancer
Academic article
2009
-
Røe, Oluf Dimitri;
Anderssen, Endre;
Helge, Eli;
Pettersen, Caroline Hild;
Olsen, Karina Standahl;
Sandeck, H.
(2009)
Genome-Wide Profile of Pleural Mesothelioma versus Parietal and Visceral Pleura: The emerging Gene Portrait of the Mesothelioma Phenotype.
PLOS ONE
Academic article
2008
-
Røe, Oluf Dimitri;
Creaney, J;
Lundgren, Steinar;
Larsson, Erik;
Sandech, Helmut;
Boffetta, P.
(2008)
Mesothelin-related Predictive and Prognostic Factors in Malignant Mesothelioma, a nested case-control study.
Lung Cancer
Academic article
-
Røe, Oluf Dimitri.
(2008)
Malignant Mesothelioma: Virus, Biomarkers and Genes- a Translational Approach.
Norges teknisk-naturvitenskapelige universitet
Doktoravhandlinger ved NTNU, 1503-8181; 2008:275 (Dissertations at the Faculty of Medicine, 0805-7680; 370)
Doctoral dissertation
2007
-
Kjaerheim, K;
Røe, Oluf Dimitri;
Waterboer, T;
Sehr, P;
Rizk, R;
Dai, HY.
(2007)
Absence of SV40 antibodies or DNA fragments in prediagnostic mesothelioma serum samples.
International Journal of Cancer
Academic article
Journal publications
-
Pestarino, Luca;
Fortner, Shannon Renee Turzanski;
Nøst, Therese Haugdahl;
Fotopoulos, Ioannis;
Urbarova, Ilona H.;
Røe, Oluf Dimitri.
(2025)
Recommendations for Validating Omics Prediction Models: Insights from a Lung Cancer RNA Biomarker Study.
Cancer Epidemiology, Biomarkers and Prevention
Academic article
-
Asphaug, Lars;
Akslen, Lars Andreas;
Blix, Egil Støre;
Boge, Beate;
Borgen, Elin Faye;
Brekke, Marianne B..
(2025)
Cost-Effectiveness of Prosigna for Adjuvant Treatment Decisions in Early Breast Cancer: Healthcare Sector - and Societal Perspectives.
Clinical Breast Cancer
Academic article
-
Gisvold, Sven Erik;
Wyller, Torgeir Bruun;
Grøttumsbråten, Janne;
Haug, Lene C.;
Hove, Aud;
Haukelien, Heidi.
(2025)
Helseforetaksmodellen: En ulykke for norsk helsevesen.
Feature article
-
Wu, Chen;
Røe, Oluf Dimitri;
Wei, Jia.
(2024)
Editorial: Direct or indirect endocrine and metabolic consequences of malignancies.
Frontiers in Endocrinology
Editorial
-
Fotopoulos, Ioannis;
Nguyen, Olav Toai Duc;
Nøst, Therese Haugdahl;
Markaki, Maria;
Lagani, Vincenzo;
Mjelle, Robin.
(2024)
Promising microRNAs in pre-diagnostic serum associated with lung cancer up to eight years before diagnosis: a HUNT study.
Journal of Cancer Research and Clinical Oncology
Academic article
-
Ohnstad, Hege Oma;
Blix, Egil Støre;
Akslen, Lars Andreas;
Gilje, Bjørnar;
Raj, Sunil Xavier;
Skjerven, Helle.
(2024)
Impact of Prosigna test on adjuvant treatment decision in lymph node-negative early breast cancer—a prospective national multicentre study (EMIT-1).
ESMO Open
Academic article
-
Nguyen, Olav Toai Duc;
Ioannis, Fotopoulos;
Nøst, Therese Haugdahl;
Maria, Markaki;
Vincenzo, Lagani;
Ioannis, Tsamardinos.
(2024)
The HUNT lung-SNP model: genetic variants plus clinical variables improve lung cancer risk assessment over clinical models.
Journal of Cancer Research and Clinical Oncology
Academic article
-
Zandwijk, Nico van;
Frank, Arthur L.;
Reid, Glen;
Røe, Oluf Dimitri;
Amos, Christopher I..
(2024)
Asbestos-Related lung Cancer: An underappreciated oncological issue.
Lung Cancer
Academic article
-
Nguyen, Olav Toai Duc;
Fotopoulos, Ioannis;
Markaki, Maria;
Tsamardinos, Ioannis;
Lagani, Vincenzo;
Røe, Oluf Dimitri.
(2024)
Improving Lung Cancer Screening Selection: The HUNT Lung Cancer Risk Model for Ever-Smokers Versus the NELSON and 2021 United States Preventive Services Task Force Criteria in the Cohort of Norway: A Population-Based Prospective Study.
JTO Clinical and Research Reports
Academic article
-
Andersen, Gøran Troseth;
Zhao, Chun Mei;
Grønbech, Jon Erik;
Chen, Yijiang;
Zayachkivska, Oksana;
Røe, Oluf Dimitri.
(2023)
Clinical aspects in translational research on gastric tumorigenesis and development of new treatments*.
Праці Наукового товариства імені Шевченка. Медичні науки
Academic literature review
-
Gisvold, Sven Erik;
Jensen, Bjarne;
Haug, Lene;
Wyller, Torgeir Bruun;
Hove, Aud;
Rangønes, Ingrid Ovidie.
(2023)
Et todelt helsevesen.
Feature article
-
Bjerner, Lars;
Bratt, Ola;
Aas, Kirsti;
Albertsen, Peter C.;
Fosså, Sophie D.;
Kvåle, Rune.
(2023)
Baseline Serum Prostate-specific Antigen Value Predicts the Risk of Subsequent Prostate Cancer Death—Results from the Norwegian Prostate Cancer Consortium.
European Urology
Academic article
-
Yuce, Tuna Han;
Ak, Guntulu;
Metintas, Selma;
Dundar, Emine;
Røe, Oluf Dimitri;
Panou, Vasiliki.
(2023)
BAP1, Wilms’ tumor 1, and calretinin in predicting survival and response to first-line chemotherapy in patients with pleural mesothelioma.
Journal of Cancer Research and Clinical Oncology
Academic article
-
Røe, Oluf Dimitri;
Creaney, Jenette.
(2022)
Response to “Revisiting ‘BAP1ness’ in Malignant Pleural Mesothelioma”.
Journal of Thoracic Oncology
Reader opinion piece
-
Dalsgaard, Sofie Bünemann;
Würtz, Else Toft;
Hansen, Johnni;
Røe, Oluf Dimitri;
Omland, Øyvind.
(2022)
Cancer incidence and risk of multiple cancers after environmental asbestos exposure in childhood—a long-term register-based cohort study.
International Journal of Environmental Research and Public Health (IJERPH)
Academic article
-
Dalsgaard, Sofie Bünemann;
Würtz, Else Toft;
Hansen, Johnni;
Røe, Oluf Dimitri;
Omland, Øyvind.
(2022)
A Cohort Study on Cancer Incidence among Women Exposed to Environmental Asbestos in Childhood with a Focus on Female Cancers, including Breast Cancer.
International Journal of Environmental Research and Public Health (IJERPH)
Academic article
-
Røe, Oluf Dimitri;
Fotopoulos, I;
Nguyen, Olav Toai Duc;
Nøst, Therese Haugdahl;
Markaki, M;
Lagani, Vincenzo.
(2022)
Common MicroRNAs in Pre-diagnostic Serum Associated with Lung Cancer in Two Cohorts up to Eight Years Before Diagnosis: A HUNT Study.
Journal of Thoracic Oncology
Abstract
-
Nguyen, Olav Toai Duc;
Fotopoulos, I;
Nøst, Therese Haugdahl;
Markaki, M;
Lagani, Vincenzo;
Tsamardinos, I.
(2022)
Genetic Variants of HUNT Lung Cancer Model Improve Lung Cancer Risk Assessment Over Clinical Models.
Journal of Thoracic Oncology
Abstract
-
Louw, Amber;
Panou, Vasiliki;
Szejniuk, Weronika Maria;
Meristoudis, Christos;
Chai, Siaw Ming;
Vliet, Chris van.
(2022)
BAP1 Loss by Immunohistochemistry Predicts Improved Survival to First-Line Platinum and Pemetrexed Chemotherapy for Patients With Pleural Mesothelioma: A Validation Study.
Journal of Thoracic Oncology
Academic article
-
Lynggård, Louise Andersen;
Panou, Vasiliki;
Szejniuk, Weronika;
Røe, Oluf Dimitri;
Meristoudis, Christos.
(2022)
Diagnostic capacity of BAP1 and MTAP in cytology from effusions and biopsy in mesothelioma.
Journal of the American Society of Cytopathology (JASC)
Academic article
-
Ma, Ling;
Chen, Guosheng;
Wang, Deqiang;
Zhang, Kai;
Zhao, Fengjiao;
Tang, Jie.
(2022)
A nomogram to predict survival probability of gastric cancer patients undergoing radical surgery and adjuvant chemotherapy.
Frontiers in Oncology
Academic article
-
Urbarova, Ilona H.;
Nøst, Therese Haugdahl;
Skogholt, Anne Heidi;
Mjelle, Robin;
Paulsen, Erna-Elise;
Dønnem, Tom.
(2022)
Increased Levels of mRNAs and miRNAs Associated with Imminent and Advanced Lung Cancer.
Journal of Thoracic Oncology
Abstract
-
Nøst, Therese Haugdahl;
Skogholt, Anne Heidi;
Urbarova, Ilona Halva;
Mjelle, Robin;
Paulsen, Erna-Elise;
Dønnem, Tom.
(2022)
Increased levels of microRNA-320 in blood serum and plasma is associated with imminent and advanced lung cancer.
Molecular Oncology
Academic article
-
Jensen, Bjarne;
Haug, Lene;
Gisvold, Sven Erik;
Grøttumsbråten, Janne;
Hove, Aud;
Isumhaugen, Mariann.
(2021)
Farvel til helseforetakene?.
Feature article
-
Papoutsoglou, Georgios;
Karaglani, Makrina;
Lagani, Vincenzo;
Thomson, Naomi;
Røe, Oluf Dimitri;
Tsamardinos, Ioannis.
(2021)
Automated machine learning optimizes and accelerates predictive modeling from COVID-19 high throughput datasets.
Scientific Reports
Academic article
-
Petersen, Thomas Ringgaard;
Panou, Vasiliki;
Meristoudis, Christos;
Weinreich, Ulla Møller;
Røe, Oluf Dimitri.
(2021)
Clinical prognostic factors in pleural mesothelioma: best supportive care and anti-tumor treatments in a real-life setting.
Acta Oncologica
Academic article
-
Szejniuk, Weronika Maria;
Nielsen, Martin Skovmos;
Takács-Szabó, Zsuzsanna;
Pawlowski, Jacek;
Al-Saadi, Sahar Sulaiman;
Maidas, Panagiotis.
(2021)
High-dose thoracic radiation therapy for non-small cell lung cancer: a novel grading scale of radiation-induced lung injury for symptomatic radiation pneumonitis.
Radiation Oncology
Academic article
-
Szejniuk, Weronika Maria;
Cekala, M.;
Bøgsted, Martin;
Meristoudis, Christos;
McCulloch, Tine;
Falkmer, Ursula.
(2021)
Adjuvant platinum-based chemotherapy in non-small cell lung cancer: The role of relative dose-intensity and treatment delay.
Cancer Treatment and Research Communications
Academic article
-
Wyller, Torgeir Bruun;
Gisvold, Sven Erik;
Grøttumsbråten, Janne;
Haug, Lene;
Hove, Aud;
Isumhaugen, Mariann.
(2021)
Sykehusreformen har skapt mer byråkrati og svekket samarbeidet.
Feature article
-
Wyller, Torgeir Bruun;
Gisvold, Sven Erik;
Grøttumsbråten, Janne;
Haug, Lene;
Hove, Aud;
Isumhaugen, Mariann.
(2021)
Sykehusreformen har skapt byråkrati og svekket samarbeidet.
Feature article
-
Nguyen, Olav Toai Duc;
Sundstrøm, Stein Harald;
Westvik, Ganna Surzhykova;
Røttereng, Ane Karoline Stræte;
Melhus, Mona Røli;
Bergseth, Cecilie.
(2020)
Major durable response of pembrolizumab in chemotherapy refractory small cell bladder cancer: A case report.
Case Reports in Oncology
Academic article
-
Røe, Oluf Dimitri.
(2020)
Democratic and ethical problem of lung cancer screening: Exclusion of true high-risk populations. Can it be fixed? Yes.
BMJ Open Respiratory Research
Academic literature review
-
Würtz, Else Toft;
Hansen, Johnni;
Røe, Oluf Dimitri;
Omland, Øyvind.
(2020)
Asbestos exposure and haematological malignancies: a Danish cohort study.
European Journal of Epidemiology (EJE)
Academic article
-
Panou, Vasiliki;
Røe, Oluf Dimitri.
(2020)
Inherited Genetic Mutations and Polymorphisms in Malignant Mesothelioma: A Comprehensive Review.
International Journal of Molecular Sciences
Academic literature review
-
Røe, Oluf Dimitri;
Markaki, Maria;
Tsamardinos, Ioannis;
Lagani, Vincenzo;
Nguyen, Olav Toai Duc;
Pedersen, Jesper Holst.
(2019)
‘Reduced’ HUNT model outperforms NLST and NELSON study criteria in predicting lung cancer in the Danish screening trial.
BMJ Open Respiratory Research
Academic article
-
Szejniuk, Weronika Maria;
Nielsen, Martin Skovmos;
Brønnum, Dorthe;
Takacs-Szabo, Z;
Weinreich, Ulla Møller;
Thomsen, L Pilegaard.
(2019)
Fractional exhaled nitric oxide as a potential biomarker for radiation pneumonitis in patients with non-small cell lung cancer: A pilot study.
Clinical and Translational Radiation Oncology
Academic article
-
Lakiotaki, Kleanthi;
Georgakopoulos, George;
Castanas, Elias;
Røe, Oluf Dimitri;
Borboudakis, Giorgos;
Tsamardinos, Ioannis.
(2019)
A data driven approach reveals disease similarity on a molecular level.
npj Systems Biology and Applications
Academic article
-
Panou, Vasiliki;
Vyberg, Mogens;
Meristoudis, Christos;
Hansen, Johnni;
Bøgsted, Martin;
Omland, Øyvind.
(2019)
Non-occupational exposure to asbestos is the main cause of malignant mesothelioma in women in North Jutland, Denmark.
Scandinavian Journal of Work, Environment and Health
Academic article
-
Dalsgaard, Sofie Bunemann;
Würtz, Else Toft;
Hansen, Johnni;
Røe, Oluf Dimitri;
Omland, Øyvind.
(2019)
Environmental asbestos exposure in childhood and risk of mesothelioma later in life: A long-term follow-up register-based cohort study.
Occupational and Environmental Medicine
Academic article
-
Szejniuk, Weronika Maria;
Robles, Ana I.;
McCulloch, Tine;
Falkmer, Ursula;
Røe, Oluf Dimitri.
(2018)
Epigenetic predictive biomarkers for response or outcome to platinum-based chemotherapy in non-small cell lung cancer, current state-of-art.
The Pharmacogenomics Journal
Academic article
-
Panou, Vasiliki;
Gadiraju, Meghana;
Wolin, Arthur;
Weipert, Caroline M.;
Skarda, Emily;
Husain, Aliya N..
(2018)
Frequency of germline mutations in cancer susceptibility genes in malignant mesothelioma.
Journal of Clinical Oncology
Academic article
-
Røe, Oluf Dimitri.
(2018)
Mesothelioma diagnosis and prognosis, are we moving beyond histology and performance status towards circulating biomarkers?.
Journal of Thoracic Disease (JTD)
Editorial
-
Markaki, Maria Dorothea Haaberg;
Tsamardinos, Ioannis;
Langhammer, Arnulf;
Lagani, Vincenzo;
Hveem, Kristian;
Røe, Oluf Dimitri.
(2018)
A Validated Clinical Risk Prediction Model for Lung Cancer in Smokers of All Ages and Exposure Types: A HUNT Study.
EBioMedicine
Academic article
-
Rangul, Vegar;
Sund, Erik Reidar;
Mork, Paul Jarle;
Røe, Oluf Dimitri;
Bauman, Adrian.
(2018)
The associations of sitting time and physical activity on total and site-specific cancer incidence: Results from the HUNT study, Norway.
PLOS ONE
Academic article
-
Røe, Oluf Dimitri;
Wahl, Sissel Gyrid Freim.
(2017)
The undifferentiated carcinoma that became a melanoma: Re-biopsy of a cancer of an unknown primary site: a case report.
Journal of Medical Case Reports
Academic article
-
Røe, Oluf Dimitri.
(2017)
The High Cost of New Cancer Therapies-A Challenge of Inequality for All Countries.
JAMA Oncology
Academic article
-
Wang, Q;
Chen, Q;
Zhu, L;
Chen, M;
Xu, W;
Panday, S.
(2017)
JWA regulates TRAIL-induced apoptosis via MARCH8-mediated DR4 ubiquitination in cisplatin-resistant gastric cancer cells.
Oncogenesis
Academic article
-
Li, Qiang;
Zhi, Xiaofei;
Zhou, Jianping;
Tao, Ran;
Zhang, Jiaxuan;
Chen, Peisheng.
(2016)
Circulating tumor cells as a prognostic and predictive marker in gastrointestinal stromal tumors: A prospective study.
OncoTarget
Academic article
-
Qian, Jing;
Qian, Yingying;
Wang, Jian;
Gu, Bing;
Pei, Dong;
He, Shaohua.
(2016)
A clinical prognostic scoring system for resectable gastric cancer to predict survival and benefit from paclitaxel- or oxaliplatin-based adjuvant chemotherapy.
Drug Design, Development and Therapy
Academic article
-
Qian, Jing;
Zhu, Weiyou;
Wang, Keming;
Ma, Lin;
Xu, Jin;
Xu, Tongpeng.
(2016)
JWA loss promotes cell migration and cytoskeletal rearrangement by affecting HER2 expression and identifies a high-risk subgroup of HER2-positive gastric carcinoma patients.
OncoTarget
Academic article
-
Chen, Xiao-Feng;
Qian, Jing;
Pei, Dong;
Zhou, Chen;
Røe, Oluf Dimitri;
Zhu, Fang.
(2016)
Prognostic value of perioperative leukocyte count in resectable gastric cancer.
World Journal of Gastroenterology (WJG)
Academic article
-
Zhi, Xiaofei;
Jiang, Baofei;
Yu, Junbo;
Røe, Oluf Dimitri;
Qin, Jun;
Ni, Qingfeng.
(2016)
Prognostic role of microscopically positive margins for primary gastrointestinal stromal tumors: a systematic review and meta-analysis.
Scientific Reports
Academic article
-
Robles, Ana I.;
Olsen, Karina Standahl;
Tsui, Dana W.T.;
Georgoulias, Vassilis;
Creaney, Jenette;
Dobra, Katalin.
(2016)
Excerpts from the 1st international NTNU symposium on current and future clinical biomarkers of cancer: innovation and implementation, June 16th and 17th 2016, Trondheim, Norway.
Journal of Translational Medicine
Academic article
-
Røe, Oluf Dimitri;
Panou, V.
(2016)
Pemetrexed as first or second line in 112 danish patients.
Journal of Clinical Oncology
Abstract
-
Røe, Oluf Dimitri;
Mjelle, Robin;
Sætrom, Pål;
Andreassen, Trygve;
Bathen, Tone Frost;
Hveem, Kristian.
(2016)
Serum microRNAs/enriched pathways in lung cancer 1-4 years before diagnosis: A pilot study from the HUNT Biobank, Norway.
Journal of Clinical Oncology
Abstract
-
Zhu, Weiyou;
Røe, Oluf Dimitri;
Wu, Chen;
Li, Wei;
Guo, Renhua;
Gu, Yanhong.
(2015)
Activity of pemetrexed-based regimen as first-line chemotherapy for advanced non-small cell lung cancer with asymptomatic inoperable brain metastasis: A retrospective study.
Journal of chemotherapy
Academic article
-
Røe, Oluf Dimitri;
Stella, Giulia Maria.
(2015)
Malignant pleural mesothelioma: History, controversy and future of a manmade epidemic.
European Respiratory Review
Academic literature review
-
Gao, Zhibin;
Hiroshima, Kenzo;
Wu, Xiaodong;
Zhang, Jixian;
Shao, Dichu;
Shao, Huajiang.
(2015)
Asbestos textile production linked to malignant peritoneal and pleural mesothelioma in women: Analysis of 28 cases in Southeast China.
American Journal of Industrial Medicine
Academic article
-
Panou, V;
Vyberg, M;
Weinreich, UM;
Meristoudis, C;
Falkmer, UG;
Røe, Oluf Dimitri.
(2015)
The established and future biomarkers of malignant pleural mesothelioma.
Cancer Treatment Reviews
Academic literature review
-
Røe, Oluf Dimitri;
Wyller, Torgeir Bruun.
(2015)
Hva står på spill med lokalsykehusene? :.
Bioingeniøren
Reader opinion piece
-
Chen, Y;
Huang, Y;
Huang, Yulin;
Xia, X;
Zhang, J;
Zhou, Y.
(2014)
JWA suppresses tumor angiogenesis via Sp1-activated matrix metalloproteinase-2 and its prognostic significance in human gastric cancer.
Carcinogenesis
Academic article
-
Cao, Hailong;
Zhou, Qing;
Lan, Rongfang;
Røe, Oluf Dimitri;
Chen, Xin;
Chen, Yijiang.
(2014)
A functional polymorphism C-509t in TGF-1 promoter contributes to susceptibility and prognosis of lone atrial fibrillation in chinese population.
PLOS ONE
Academic article
-
Kerkentzes, Konstantinos;
Lagani, Vincenzo;
Tsamardinos, Ioannis;
Vyberg, Mogens;
Røe, Oluf Dimitri.
(2014)
Hidden treasures in "ancient" microarrays: Gene expression portrays biology and potential resistance pathways of major lung cancer subtypes and normal tissue.
Frontiers in Oncology
Academic article
-
Cao, Hailong;
Zhu, Jinfu;
Xi, Lei;
Røe, Oluf Dimitri;
Chen, Yijiang;
Wang, Dongjin.
(2014)
Preoperative serum receptor activator of nuclear factor-κB ligand/osteoprotegerin predict stabilization of spontaneously restored sinus rhythm in persistent atrial fibrillation patients after mitral valve surgery.
Cardiology
Academic article
-
Røe, Oluf Dimitri;
Oppegaard, Per Arne;
Revheim, Mona Elisabeth;
Svindland, Aud.
(2014)
Adrenocortical carcinoma mimicking lung cancer and responding to vinorelbine/carboplatin and pemetrexed/carboplatin.
BMJ Case Reports
Academic article
-
Xu, W;
Chen, Q;
Wang, Q;
Sun, Y;
Wang, S;
Li, A.
(2014)
JWA reverses cisplatin resistance via the CK2-XRCC1 pathway in human gastric cancer cells.
Cell Death & Disease
Academic article
-
Huang, Yefei;
Wang, Weimin;
Chen, Yansu;
Huang, Yulin;
Zhang, Jianbing;
He, Song.
(2014)
The opposite prognostic significance of nuclear and cytoplasmic p21 expression in resectable gastric cancer patients.
Journal of gastroenterology
Academic article
-
Cao, Hailong;
Wu, Ying;
Li, Qingguo;
Wu, Yanhu;
Zhou, Qing;
Røe, Oluf Dimitri.
(2014)
Serum sRANKL/OPG predict recurrence after radiofrequency catheter ablation of lone atrial fibrillation.
International Journal of Cardiology
Academic article
-
Xu, W;
Wang, S;
Chen, Q;
Zhang, Y;
Ni, P;
Wu, X.
(2014)
TXNL1-XRCC1 pathway regulates cisplatin-induced cell death and contributes to resistance in human gastric cancer.
Cell Death & Disease
Academic article
-
Røe, Oluf Dimitri.
(2014)
Postoperative leukopenia is an independent prognostic factor in resectable gastric cancer patients.
Journal of Clinical Oncology
Abstract
-
Chen, X;
Zhu, Q;
Liu, Y;
Liu, P;
Yin, Y;
Guo, R.
(2014)
Icotinib is an active treatment of non-small-cell lung cancer: A retrospective study.
PLOS ONE
Academic article
-
Ye, Yang;
Li, Xuan;
Yang, Jiangjing;
Miao, Shuhan;
Wang, Shouyu;
Chen, Yansu.
(2013)
MDM2 is a useful prognostic biomarker for resectable gastric cancer.
Cancer Science
Academic article
-
Cao, HaiLong;
Li, Qingguo;
Li, Mingna;
Røe, Oluf Dimitri;
Wu, Zhong;
Zhou, Qing.
(2013)
Osteoprotegerin/RANK/RANKL axis and atrial remodeling in mitral valvular patients with atrial fibrillation.
International Journal of Cardiology
Academic article
-
Chen, Xiaofeng;
Liu, YQ;
Røe, Oluf Dimitri;
Qian, YY;
Guo, RH;
Zhu, LJ.
(2013)
Gefitinib or Erlotinib as Maintenance Therapy in Patients with Advanced Stage Non-Small Cell Lung Cancer: A Systematic Review.
PLOS ONE
Academic article
-
Xu, CH;
Wu, C;
Xia, Y;
Zhong, ZP;
Liu, Xiang;
Xu, Jing.
(2013)
WT1 Promotes Cell Proliferation in Non-Small Cell Lung Cancer Cell Lines Through Up-Regulating Cyclin D1 and p-pRb In Vitro and In Vivo.
PLOS ONE
Academic article
-
Cao, Hailong;
Zhou, Qing;
Wu, Yanhu;
Li, Qingguo;
Røe, Oluf Dimitri;
Chen, Yijiang.
(2013)
Preoperative serum soluble receptor activator of nuclear factor-kappa B ligand and osteoprotegerin predict postoperative atrial fibrillation in patients undergoing cardiac valve surgery.
Annals of Thoracic Surgery
Academic article
-
Røe, Oluf Dimitri.
(2013)
DNA repair suppression and effect of cisplatin in mesothelioma and lung cancer cell lines.
Journal of Clinical Oncology
Abstract
-
Chen, Yansu;
Xia, Xiaowei;
Wang, Shouyu;
Wu, Xuming;
Zhang, Jianbing;
Zhou, Yan.
(2013)
High FAK combined with low JWA expression: clinical prognostic and predictive role for adjuvant fluorouracil-leucovorin-oxaliplatin treatment in resectable gastric cancer patients.
Journal of gastroenterology
Academic article
-
Xi, Lei;
Cao, HaiLong;
Zhu, Jinfu;
Røe, Oluf Dimitri;
Li, Mingna;
Wu, Yanhu.
(2013)
OPG/RANK/RANKL Axis in Stabilization of Spontaneously Restored Sinus Rhythm in Permanent Atrial Fibrillation Patients after Mitral Valve Surgery.
Cardiology
Academic article
-
Chen, Xiaofeng;
Zha, Xiaoming;
Chen, Wei;
Zhu, Tingting;
Qiu, Jinrong;
Røe, Oluf Dimitri.
(2013)
Leptin attenuates the anti-estrogen effect of tamoxifen in breast cancer.
Biomedicine & Pharmacotherapy
Academic article
-
Wang, Shouyu;
Wu, Xuming;
Zhang, Jianbing;
Chen, Yansu;
Xu, Jin;
Xia, Xiaowei.
(2013)
CHIP functions as a novel suppressor of tumour angiogenesis with prognostic significance in human gastric cancer.
Gut
Academic article
-
Tsamardinos, I;
Borboudakis, G;
Christodoulou, EG;
Røe, Oluf Dimitri.
(2012)
Chemosensitivity Prediction of Tumours Based on Expression, miRNA, and Proteomics Data.
International Journal of Systems Biology and Biomedical Technologies
Academic article
-
Røe, Oluf Dimitri;
Szulkin, Adam;
Anderssen, Endre;
Flatberg, Arnar;
Sandeck, Helmut;
Amundsen, Tore.
(2012)
Molecular Resistance Fingerprint of Pemetrexed and Platinum in a Long-Term Survivor of Mesothelioma.
PLOS ONE
Academic article
-
Chen, X.-F.;
Wang, R;
Yin, YM;
Røe, Oluf Dimitri;
Li, J;
Zhu, LJ.
(2012)
The effect of monosialotetrahexosylganglioside (GM1) in prevention of oxaliplatin induced neurotoxicity: A retrospective study.
Biomedicine & Pharmacotherapy
Academic article
-
Wang, SY;
Wu, XM;
Chen, YS;
Zhang, JB;
Ding, JJ;
Zhou, Yan.
(2012)
Prognostic and Predictive Role of JWA and XRCC1 Expressions in Gastric Cancer.
Clinical Cancer Research
Academic article
-
Chen, Xiaofeng;
Liu, YQ;
Yin, YM;
Jin, S;
Ping, GQ;
Røe, Oluf Dimitri.
(2012)
Recombinant human endostatin (endostar) decreased recurrent ascites, pleural fluid and ascitic VEGF in a case of advanced mesothelioma.
Journal of chemotherapy
Academic article
-
Liu, Xin;
Wang, Shouyu;
Xia, Xiaowei;
Chen, Yansu;
Zhou, Yan;
Wu, Xuming.
(2012)
Synergistic Role between p53 and JWA: Prognostic and Predictive Biomarkers in Gastric Cancer.
PLOS ONE
Academic article
-
Cao, HaiLong;
Wang, Jian;
Xi, Lei;
Røe, Oluf Dimitri;
Chen, Yijiang;
Wang, Dongjin.
(2011)
Dysregulated Atrial Gene Expression of Osteoprotegerin/Receptor Activator of Nuclear Factor-kappa B (RANK)/RANK Ligand Axis in the Development and Progression of Atrial Fibrillation.
Circulation Journal
Academic article
-
Sandeck, Helmut;
Røe, Oluf Dimitri;
Kjærheim, Kristina;
Willèn, Helena;
Larsson, Erik.
(2010)
Re-evaluation of histological diagnoses of malignant mesothelioma by immunohistochemistry.
Diagnostic Pathology
Academic article
-
Røe, Oluf Dimitri;
Anderssen, Endre;
Sandeck, Helmut;
Christensen, Tone;
Larsson, Erik;
Lundgren, Steinar.
(2010)
Malignant pleural mesothelioma: Genome-wide expression patterns reflectinggeneral resistance mechanisms and a proposal of novel targets.
Lung Cancer
Academic article
-
Røe, Oluf Dimitri;
Anderssen, Endre;
Helge, Eli;
Pettersen, Caroline Hild;
Olsen, Karina Standahl;
Sandeck, H.
(2009)
Genome-Wide Profile of Pleural Mesothelioma versus Parietal and Visceral Pleura: The emerging Gene Portrait of the Mesothelioma Phenotype.
PLOS ONE
Academic article
-
Røe, Oluf Dimitri;
Creaney, J;
Lundgren, Steinar;
Larsson, Erik;
Sandech, Helmut;
Boffetta, P.
(2008)
Mesothelin-related Predictive and Prognostic Factors in Malignant Mesothelioma, a nested case-control study.
Lung Cancer
Academic article
-
Kjaerheim, K;
Røe, Oluf Dimitri;
Waterboer, T;
Sehr, P;
Rizk, R;
Dai, HY.
(2007)
Absence of SV40 antibodies or DNA fragments in prediagnostic mesothelioma serum samples.
International Journal of Cancer
Academic article
Report
-
Røe, Oluf Dimitri.
(2008)
Malignant Mesothelioma: Virus, Biomarkers and Genes- a Translational Approach.
Norges teknisk-naturvitenskapelige universitet
Doktoravhandlinger ved NTNU, 1503-8181; 2008:275 (Dissertations at the Faculty of Medicine, 0805-7680; 370)
Doctoral dissertation
Outreach
2024
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Academic lectureNguyen, Olav Toai Duc; Fotopoulos, Y; Nøst, Therese Haugdahl; Markaki, Maria; Lagani, Vincenzo; Sætrom, Pål. (2024) Differentially expressed microRNAs in prediagnostic serum linked to lung cancer up to eight years before diagnosis in prospective, population-based cohorts: A HUNT study. Clinical Science Symposium, 2024 ASCO Annual Meeting 2024-05-29 -
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Academic lectureNguyen, Olav Toai Duc; Fotopoulos, Y; Nøst, Therese Haugdahl; Markaki, Maria; Lagani, Vincenzo; Tsamadinos, Ioannis. (2024) Effect of novel polygenetic variant of HUNT lung cancer model on lung cancer risk assessment over clinical model among light smokers (average <9 pack-years). Clinical Science Symposium, 2024 ASCO Annual Meeting 2024-05-29 -
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PosterRøe, Oluf Dimitri; Nguyen, Olav Toai Duc; Ashraf, Haseem. (2024) Improving Lung Cancer Screening Selection: Hunt Lung Cancer Model (HUNT LCM) versus PLCOm2012, early results after two rounds of screening in a prospective screening pilot study in Norway (TIDL). ESMO , Barcelona 2024-09-13 - 2024-09-17
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PosterNguyen, Olav Toai Duc; Røe, Oluf Dimitri. (2024) Ethical Lung Cancer Screening Selection? Comparison of the the European 4 - In The Long Run (4ITLR) criteria with the 2021 USPSTF (US), and HUNT Lung Cancer Risk Model in a large Norwegian Prospective Population-Based study. ESMO , Barcelona 2024-09-13 - 2024-09-17
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PosterNguyen, Olav Toai Duc; Røe, Oluf Dimitri. (2024) Differentially expressed microRNAs in prediagnostic serum linked to lung cancer up to eight years before diagnosis in prospective, population-based cohorts: A HUNT study. ASCO , Chicago 2024-05-31 - 2024-06-03
2022
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PosterNøst, Therese Haugdahl; Urbarova, Ilona Halva; Skogholt, Anne Heidi; Mjelle, Robin; Paulsen, Erna Elise; Dønnem, Tom. (2022) Increased levels of mRNAs and miRNAs associated with imminent and advanced lung cancer. IASLC 2022 World Conference on Lung Cancer , Wien 2022-08-06 - 2022-08-09
2016
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InterviewRøe, Oluf Dimitri. (2016) Studieresultater fra HUNT kan gi tidlig lungekreft-svar. Trønder-avisa Trønder-avisa [Internet] 2016-06-10
2014
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Interview
2013
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PosterRøe, Oluf Dimitri; Chen, Duan; Chen, Wu; Chen, Yijiang; Zhi, Xiaofei. (2013) DNA repair suppression and effect of cisplatin in mesothelioma and lung cancer cell lines. ASCO 2013 , Chicago 2013-05-30 - 2013-06-03
2012
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PosterRøe, Oluf Dimitri. (2012) Differentially expressed genes of major lung tumour subtypes and normal lung tissue. Proceedings of the 7th conference of the Hellenic Society for Computational Biology & Bioinformatics - HSCBB12 FORTH, Heraklion, , Heraklion 2012-10-04 - 2012-10-06
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PosterRøe, Oluf Dimitri. (2012) Mesothelioma cluster in a medium sized hospital in South-East China: Relations to asbestos exposure and clinicopathological findings. IMIG 2012 , Boston 2012-09-11 - 2012-09-14
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Academic lectureRøe, Oluf Dimitri. (2012) MicroRNA in Cancer. Nanjing Medical University , Nanjing Medical University 2012-12-15 - 2012-12-15
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PosterRøe, Oluf Dimitri. (2012) Cell cycle checkpoint genes and homologous recombinational repair are overexpressed in malignant pleural mesothelioma. IMIG 2012 , Boston 2012-09-11 - 2012-09-14
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Academic lectureRøe, Oluf Dimitri. (2012) Fanconi anemia genes, RHINO and other cell cycle checkpoint genes are overexpressed in malignant pleural mesothelioma. The 3rd Erling Seeberg symposium, June 2012 in Trondheim and Ørland, Norway , Ørland 2012-06-19 - 2012-06-24
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PosterRøe, Oluf Dimitri. (2012) Comparative evaluation of Affymetrix and Illumina genome-wide expression data in Pleural Mesothelioma. 7th conference of the Hellenic Society for Computational Biology & Bioinformatics - HSCBB12 FORTH, Heraklion, Crete, , Heraklion 2012-10-04 - 2012-10-06
2011
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PosterRøe, Oluf Dimitri. (2011) Information-Preserving Techniques Improve Chemosensitivity Prediction of Tumours Based on Expression Profiles. Engineering Applications of Neural Networks - 12th INNS EANN-SIG International Conference, EANN 2011 and 7th IFIP WG 12.5 International Conference, AIAI 2011 , Corfu 2011-09-12 - 2011-09-18
2006
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PosterRøe, Oluf Dimitri; Andersen, Endre; Helge, Eli; Standahl-Olsen, Karina; Larsson, Erik; Lundgren, Steinar. (2006) Microarray of normal mesothelium and mesothelioma-visceral and parietal pleura has distinct gene expression profile-consequences for oncogenesis of mesothelioma?. 8th International Conference of the International Mesothelioma Interest Group , Chicago, Illinois 2006-10-19 - 2006-10-22
2005
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PosterRøe, Oluf D; Creaney, J; Lundgren, Steinar; Larsson, Erik; Sandech, H; Bofetta, P. (2005) SMRP (Soluble Mesothelin Related Protein), CYFRA 21-1 and CA125 in serum 1-30 years before mesothelioma diagnosis: a case-control study. The International Mesothelioma Symposium 2005-11-22 - 2005-11-27