Background and activities
Bruheim group focuses on Deep Phenotyping of prokaryotic and eukaryotic model systems using Advanced Cultivation Technology and Mass Spectrometry based Metabolomics, Fluxomics and Lipidomics (http://www.ntnu.edu/biotech/research/microbial-biotechnology/bruheim-lab). Bruheim is scientific leader of the NT faculty Mass Spectrometry lab (http://www.ntnu.edu/nt-mslab). We have developed a suite of target and non-target MS methods (http://www.ntnu.edu/nt-mslab/metabolomics) which we apply on a range of biological model systems and research questions.
Teaching
TBT4140 Biochemical Engineering, TBT4500 Biotechnology Specialization Project, TBT4505 Biotechnology Specialization Course, TBT4170 Biotechnology, TBT4110 Microbiology, BT3220 Advanced Biotechnology, TKP4170/71 Process Designs, Projects Biochemical Engineering Plant Design, BT8105 Prokaryote Molecular Biology and Synthetic Biology, MEDT8010 Metabolomics - Methods and Applications
Current projects:
Trond Mohn Stiftelse: “Targeting AMR by inhibition of bacterial stress responses” (2019-2022)
NTNU Biotechnology programme: “Chemically defined cell culture media” (2019-2021)
NFR Digital Life/ Biotek2021: “DigiSal – Towards the Digital Salmon: From a reactive to a pre-emptive research strategy in aquaculture” (2016 - 2020)
NFR Digital Life/ Biotek2021: “INBioPharm - Integrated Novel Natural Product Discovery and Production Platform for Accelerated Biopharmaceutical Innovation from Microbial Biodiversity” (2016 - 2020)
NFR Digital Life/ Biotek2011:” AurOmega - Microbial production of omega-3 fatty acids - a model based approach (2017-2021)
NTNU Biotechnology programme: “Development and Application of Fluxomics tools for the study of cellular phenotypes” (2015-2019)
NFR/ Era-IB: “Zfuels – A novel bacterial system with integrated micro-bubble distillation for the production of acetaldehyde “ (2016-2019)
NTNU Helse: “Inhibition of bacterial mutagenesis and attacking a new antibacterial target with novel peptides and small molecules” (2018-2021)
NTNU IBT: “Inhibition of antibiotic resistance development through targeting bacterial translesion synthesis mechanism with novel peptide drugs” (2017-2021)
NTNU IBT: “Genetic and molecular investigation of Norwegian Farmhouse Ale yeasts” (2013 – ongoing MSc projects) (2013-)
8-10 ad hoc Metabolomics/ Fluxomics Lipidomics projects (NT-faculty, NTNU, National, International)