Rajeevkumar Raveendran Nair
Rajeevkumar Raveendran Nair
rajeevkumar.r.nair@ntnu.no
About
Currently, Core Manager/Researcher at the Viral Vector Core (VVC), Kavli Institute for Systems Neuroscience/CNC, NTNU. Viral Vector Core
PhD in Biotechnology from Rajiv Gandhi Centre for Biotechnology, Kerala, India. Thesis title: ‘Structure-Function relationships in the interactions between Calcium/calmodulin dependent protein kinase type II (CaMKII) and N-methyl-D-aspartate receptor (NMDAR) subunits’. After PhD, I joined Bramham group, UiB, Norway as Post Doctoral Fellow/Researcher (2006-2010, studying the post-translational modifications of another memory-associated protein Arc/Arg3.1). Later, I joined Tashiro group (2010-2013, investigating the role of NMDA receptors in adult-neurogenesis) and Kentros group (2013-2018, developing cell type-specific viral vectors) at Kavli Institute for Systems Neuroscience/CNC, NTNU as Post Doctoral Fellow/Researcher. Google scholar profile
Passionate in understanding the secrets of brain, interested in creating novel molecular tools, and designing & creating viral vectors to deliver genes inside the cells in a petriplate to complex mammalian brains. A Science enthusiast interested in writing blogs for communicating Science to general audience. Scientific blogs
Management Committee member representing Norway for COST Action (CA21113- Genome Editing to Treat Humans Diseases).
Publications
2022
-
Bauer, Ulrich Stefan;
Fiskum, Vegard;
Raveendran Nair, Rajeevkumar;
Wijdeven, Rosanne Francisca van de;
Kentros, Clifford;
Sandvig, Ioanna;
Sandvig, Axel.
(2022)
Validation of Functional Connectivity of Engineered Neuromuscular Junction With Recombinant Monosynaptic Pseudotyped ΔG-Rabies Virus Tracing.
Frontiers in Integrative Neuroscience.
volum 16.
Academic article
-
Jacobsen, R. Irene;
Raveendran Nair, Rajeevkumar;
Obenhaus, Horst-Andreas;
Donato, Flavio;
Slettmoen, Torstein;
Moser, May-Britt;
Moser, Edvard Ingjald.
(2022)
All-viral tracing of monosynaptic inputs to single birthdate-defined neurons in the intact brain.
Cell Reports Methods.
Academic article
-
Kobro-Flatmoen, Asgeir;
Battistin, Claudia;
Raveendran Nair, Rajeevkumar;
Bjorkli, Christiana;
Skender, Belma;
Kentros, Clifford;
Gouras, Gunnar K;
Witter, Menno.
(2022)
Lowering levels of reelin in entorhinal cortex layer II-neurons results in lowered levels of intracellular amyloid-β.
bioRxiv.
Academic article
2021
-
Nigro, Maximiliano Jose;
Kirikae, Hinaco;
Kjelsberg, Kasper;
Nair Raveendran, Rajeevkumar;
Witter, Menno P..
(2021)
Not All That Is Gold Glitters: PV-IRES-Cre Mouse Line Shows Low Efficiency of Labeling of Parvalbumin Interneurons in the Perirhinal Cortex.
Frontiers in Neural Circuits.
volum 15.
Academic article
-
Nigro, Maximiliano Jose;
Kirikae, Hinako;
Kjelsberg, Kasper;
Raveendran Nair, Rajeevkumar;
Witter, Menno.
(2021)
Not all that is gold glitters: PV-IRES-Cre mouse line shows low efficiency of labeling of parvalbumin interneurons in the perirhinal cortex.
BioRxiv.
Academic article
-
Ohara, Shinya;
Blankvoort, Stefan;
Nair Raveendran, Rajeevkumar;
Nigro, Maximiliano Jose;
Nilssen, Eirik Stamland;
Kentros, Clifford;
Witter, Menno.
(2021)
Local projections of layer Vb-to-Va are more prominent in lateral than in medial entorhinal cortex.
eLIFE.
Academic article
-
Åmellem, Ingrid;
Yovianto, Glen;
Tarng Chong, Hai;
Nair Raveendran, Rajeevkumar;
Cnops, Vanja;
Thanawalla, Ayesha;
Tashiro, Ayumu.
(2021)
Role of NMDA receptors in adult neurogenesis and normal development of the dentate gyrus.
eNeuro.
Academic article
2020
-
Madhavan, Mayadevi;
G.Mohanan, Archana;
Sarah Jacob, Reena;
Gunasekaran, Sowmya;
Nair Raveendran, Rajeevkumar;
Ramakrishnapillai V, Omkumar.
(2020)
Glu60 of α-Calcium/calmodulin dependent protein kinase II mediates crosstalk between the regulatory T-site and protein substrate binding region of the active site.
Archives of Biochemistry and Biophysics.
volum 685.
Academic article
-
Nair Raveendran, Rajeevkumar;
Blankvoort, Stefan;
Donate Lagartos, Maria Jose;
Kentros, Clifford.
(2020)
Enhancer-Driven Gene Expression (EDGE) Enables the Generation of Viral Vectors Specific to Neuronal Subtypes.
iScience.
volum 23 (3).
Academic article
2019
-
Bauer, Ulrich Stefan;
van de Wijdeven, Rosanne Francisca;
Raveendran Nair, Rajeevkumar;
Fiskum, Vegard;
Kentros, Clifford;
Sandvig, Ioanna;
Sandvig, Axel.
(2019)
Modelling functional human neuromuscular junctions in a differentially-perturbable microfluidic environment, validated through recombinant monosynaptic pseudotyped ΔG-rabies virus tracing.
BioRxiv.
Academic article
2018
-
Nair Raveendran, Rajeevkumar;
Renganathan Chandrika, Arunkumar;
Steephan, Mathew;
Sudarsana Devi, Suma Priya;
Kumar, Mantosh;
Paul, Soumya;
Madhavan, Mayadevi;
Ramakrishnapillai V, Omkumar.
(2018)
A simple end-point assay for calcium channel activity.
Cell Calcium.
volum 74.
Academic article
-
Nilssen, Eirik Stamland;
Jacobsen, Bente;
Nair Raveendran, Rajeevkumar;
Fjeld, Gunhild;
Blankvoort, Stefan;
Kentros, Clifford;
Witter, Menno.
(2018)
Inhibitory Connectivity Dominates the Fan Cell Network in Layer II of Lateral Entorhinal Cortex.
Journal of Neuroscience.
volum 38 (45).
Academic article
2017
-
Myrum, Craig;
Soule, Jonathan;
Bittins, Margarethe;
Cavagnini, Kyle;
Goff, Kevin;
Ziemek, Silje Karina;
Eriksen, Maria Steene;
Patil, Sudarshan;
Szum, Adrian;
Nair Raveendran, Rajeevkumar;
Bramham, Clive R..
(2017)
Arc interacts with the integral endoplasmic reticulum protein, calnexin.
Frontiers in Cellular Neuroscience.
volum 11:294.
Academic article
-
Nair Raveendran, Rajeevkumar;
Patil, Sudarshan;
Tiron, Adrian;
Kanhema, Tambudzai;
Panja, Debabrata;
Schiro, Lars Erik;
Parobczak, Kamil;
Wilczynski, Grzegorz M;
Bramham, Clive R..
(2017)
Dynamic Arc SUMOylation and selective interaction with F-actin-binding protein Drebrin A in LTP consolidation in vivo.
Frontiers in Synaptic Neuroscience.
volum 9:8 (MAY).
Academic article
2015
-
Hall, Malgorzata H.;
Magalska, Adriana;
Malinowska, Monika;
Ruszczycki, Blazej;
Czaban, Iwona;
Patel, Satyam;
Ambrozek-Latecka, Magdalena;
Zolocinska, Ewa;
Broszkiewicz, Hanna;
Parobczak, Kamil;
Nair Raveendran, Rajeevkumar;
Rylski, Marcin;
Pawlak, Robert;
Bramham, Clive R.;
Wilczynski, Grzegorz M.
(2015)
Localization and regulation of PML bodies in the adult mouse brain.
Brain Structure and Function.
volum Published ahead of print.
Academic article
2010
-
Bramham, Clive R. Evjen;
Alme, Maria Nordheim;
Bittins, Margarethe;
Kuipers, Sjoukje;
Nair, Rajeevkumar R;
Pai, Balagopal Sreenivasa;
Panja, Debabrata;
Schubert, Manja;
Soule, Jonathan;
Tiron, Adrian;
Wibrand, Karin.
(2010)
The Arc of synaptic memory.
Experimental Brain Research.
volum 200 (2).
Academic literature review
2009
-
Bramham, Clive R. Evjen;
Panja, Debabrata;
Tiron, Adrian;
Raveendran Nair, Rajeevkumar;
Wibrand, Karin;
Kuipers, S.
(2009)
Arc/Arg3.1 synthesis and control of LTp consolidation in the adult dentate gyrus in vivo.
European Neuropsychopharmacology.
volum 19.
Abstract
-
Raveendran Nair, Rajeevkumar;
Sudarsana Devi, Suma Priya;
Madhavan, Mayadevi;
Mathew, Steephan;
Thankayyan R., Santhoshkumar;
John, Cheriyan;
Rajendran, Sanalkumar;
Jackson, James;
Ramakrishnapillai V, Omkumar.
(2009)
Phosphorylation status of the NR2B subunit of NMDA receptor regulates its interaction with calcium/calmodulin‐dependent protein kinase II.
Journal of Neurochemistry.
volum 110.
Academic article
Journal publications
-
Bauer, Ulrich Stefan;
Fiskum, Vegard;
Raveendran Nair, Rajeevkumar;
Wijdeven, Rosanne Francisca van de;
Kentros, Clifford;
Sandvig, Ioanna;
Sandvig, Axel.
(2022)
Validation of Functional Connectivity of Engineered Neuromuscular Junction With Recombinant Monosynaptic Pseudotyped ΔG-Rabies Virus Tracing.
Frontiers in Integrative Neuroscience.
volum 16.
Academic article
-
Jacobsen, R. Irene;
Raveendran Nair, Rajeevkumar;
Obenhaus, Horst-Andreas;
Donato, Flavio;
Slettmoen, Torstein;
Moser, May-Britt;
Moser, Edvard Ingjald.
(2022)
All-viral tracing of monosynaptic inputs to single birthdate-defined neurons in the intact brain.
Cell Reports Methods.
Academic article
-
Kobro-Flatmoen, Asgeir;
Battistin, Claudia;
Raveendran Nair, Rajeevkumar;
Bjorkli, Christiana;
Skender, Belma;
Kentros, Clifford;
Gouras, Gunnar K;
Witter, Menno.
(2022)
Lowering levels of reelin in entorhinal cortex layer II-neurons results in lowered levels of intracellular amyloid-β.
bioRxiv.
Academic article
-
Nigro, Maximiliano Jose;
Kirikae, Hinaco;
Kjelsberg, Kasper;
Nair Raveendran, Rajeevkumar;
Witter, Menno P..
(2021)
Not All That Is Gold Glitters: PV-IRES-Cre Mouse Line Shows Low Efficiency of Labeling of Parvalbumin Interneurons in the Perirhinal Cortex.
Frontiers in Neural Circuits.
volum 15.
Academic article
-
Nigro, Maximiliano Jose;
Kirikae, Hinako;
Kjelsberg, Kasper;
Raveendran Nair, Rajeevkumar;
Witter, Menno.
(2021)
Not all that is gold glitters: PV-IRES-Cre mouse line shows low efficiency of labeling of parvalbumin interneurons in the perirhinal cortex.
BioRxiv.
Academic article
-
Ohara, Shinya;
Blankvoort, Stefan;
Nair Raveendran, Rajeevkumar;
Nigro, Maximiliano Jose;
Nilssen, Eirik Stamland;
Kentros, Clifford;
Witter, Menno.
(2021)
Local projections of layer Vb-to-Va are more prominent in lateral than in medial entorhinal cortex.
eLIFE.
Academic article
-
Åmellem, Ingrid;
Yovianto, Glen;
Tarng Chong, Hai;
Nair Raveendran, Rajeevkumar;
Cnops, Vanja;
Thanawalla, Ayesha;
Tashiro, Ayumu.
(2021)
Role of NMDA receptors in adult neurogenesis and normal development of the dentate gyrus.
eNeuro.
Academic article
-
Madhavan, Mayadevi;
G.Mohanan, Archana;
Sarah Jacob, Reena;
Gunasekaran, Sowmya;
Nair Raveendran, Rajeevkumar;
Ramakrishnapillai V, Omkumar.
(2020)
Glu60 of α-Calcium/calmodulin dependent protein kinase II mediates crosstalk between the regulatory T-site and protein substrate binding region of the active site.
Archives of Biochemistry and Biophysics.
volum 685.
Academic article
-
Nair Raveendran, Rajeevkumar;
Blankvoort, Stefan;
Donate Lagartos, Maria Jose;
Kentros, Clifford.
(2020)
Enhancer-Driven Gene Expression (EDGE) Enables the Generation of Viral Vectors Specific to Neuronal Subtypes.
iScience.
volum 23 (3).
Academic article
-
Bauer, Ulrich Stefan;
van de Wijdeven, Rosanne Francisca;
Raveendran Nair, Rajeevkumar;
Fiskum, Vegard;
Kentros, Clifford;
Sandvig, Ioanna;
Sandvig, Axel.
(2019)
Modelling functional human neuromuscular junctions in a differentially-perturbable microfluidic environment, validated through recombinant monosynaptic pseudotyped ΔG-rabies virus tracing.
BioRxiv.
Academic article
-
Nair Raveendran, Rajeevkumar;
Renganathan Chandrika, Arunkumar;
Steephan, Mathew;
Sudarsana Devi, Suma Priya;
Kumar, Mantosh;
Paul, Soumya;
Madhavan, Mayadevi;
Ramakrishnapillai V, Omkumar.
(2018)
A simple end-point assay for calcium channel activity.
Cell Calcium.
volum 74.
Academic article
-
Nilssen, Eirik Stamland;
Jacobsen, Bente;
Nair Raveendran, Rajeevkumar;
Fjeld, Gunhild;
Blankvoort, Stefan;
Kentros, Clifford;
Witter, Menno.
(2018)
Inhibitory Connectivity Dominates the Fan Cell Network in Layer II of Lateral Entorhinal Cortex.
Journal of Neuroscience.
volum 38 (45).
Academic article
-
Myrum, Craig;
Soule, Jonathan;
Bittins, Margarethe;
Cavagnini, Kyle;
Goff, Kevin;
Ziemek, Silje Karina;
Eriksen, Maria Steene;
Patil, Sudarshan;
Szum, Adrian;
Nair Raveendran, Rajeevkumar;
Bramham, Clive R..
(2017)
Arc interacts with the integral endoplasmic reticulum protein, calnexin.
Frontiers in Cellular Neuroscience.
volum 11:294.
Academic article
-
Nair Raveendran, Rajeevkumar;
Patil, Sudarshan;
Tiron, Adrian;
Kanhema, Tambudzai;
Panja, Debabrata;
Schiro, Lars Erik;
Parobczak, Kamil;
Wilczynski, Grzegorz M;
Bramham, Clive R..
(2017)
Dynamic Arc SUMOylation and selective interaction with F-actin-binding protein Drebrin A in LTP consolidation in vivo.
Frontiers in Synaptic Neuroscience.
volum 9:8 (MAY).
Academic article
-
Hall, Malgorzata H.;
Magalska, Adriana;
Malinowska, Monika;
Ruszczycki, Blazej;
Czaban, Iwona;
Patel, Satyam;
Ambrozek-Latecka, Magdalena;
Zolocinska, Ewa;
Broszkiewicz, Hanna;
Parobczak, Kamil;
Nair Raveendran, Rajeevkumar;
Rylski, Marcin;
Pawlak, Robert;
Bramham, Clive R.;
Wilczynski, Grzegorz M.
(2015)
Localization and regulation of PML bodies in the adult mouse brain.
Brain Structure and Function.
volum Published ahead of print.
Academic article
-
Bramham, Clive R. Evjen;
Alme, Maria Nordheim;
Bittins, Margarethe;
Kuipers, Sjoukje;
Nair, Rajeevkumar R;
Pai, Balagopal Sreenivasa;
Panja, Debabrata;
Schubert, Manja;
Soule, Jonathan;
Tiron, Adrian;
Wibrand, Karin.
(2010)
The Arc of synaptic memory.
Experimental Brain Research.
volum 200 (2).
Academic literature review
-
Bramham, Clive R. Evjen;
Panja, Debabrata;
Tiron, Adrian;
Raveendran Nair, Rajeevkumar;
Wibrand, Karin;
Kuipers, S.
(2009)
Arc/Arg3.1 synthesis and control of LTp consolidation in the adult dentate gyrus in vivo.
European Neuropsychopharmacology.
volum 19.
Abstract
-
Raveendran Nair, Rajeevkumar;
Sudarsana Devi, Suma Priya;
Madhavan, Mayadevi;
Mathew, Steephan;
Thankayyan R., Santhoshkumar;
John, Cheriyan;
Rajendran, Sanalkumar;
Jackson, James;
Ramakrishnapillai V, Omkumar.
(2009)
Phosphorylation status of the NR2B subunit of NMDA receptor regulates its interaction with calcium/calmodulin‐dependent protein kinase II.
Journal of Neurochemistry.
volum 110.
Academic article
Media
2020
-
PosterBjorkli, Christiana; Hemler, MB; Raveendran Nair, Rajeevkumar; Kobro-Flatmoen, Asgeir; Witter, Menno; Kentros, Clifford; Sandvig, Axel; Sandvig, Ioanna. (2020) Linking molecular biomarkers and behavior in rodents and patients with Alzheimer’s disease. FENS Virtual Forum 2020 . Federation of European Neuroscience Societies; 2020-07-11 - 2020-07-15.
2019
-
PosterBauer, Ulrich Stefan; van de Wijdeven, Rosanne Francisca; Raveendran Nair, Rajeevkumar; Sandvig, Ioanna; Sandvig, Axel. (2019) Developing an engineered neural network model to use in the study of amyotrophic lateral sclerosis. 3rd Nordic Neuroscience Meeting ; Helsinki. 2019-06-12 - 2019-06-14.
2018
-
PosterJacobsen, R. Irene; Donato, Flavio; Raveendran Nair, Rajeevkumar; Kentros, Clifford; Moser, May-Britt; Moser, Edvard Ingjald. (2018) How is a place field generated? Developing a method for the functional identification of inputs to a single hippocampal neuron. Grid cells and cognitive maps meeting ; London. 2018-05-21 - 2018-05-22.
-
PosterNair Raveendran, Rajeevkumar; Blankvoort, Stefan; Kentros, Clifford. (2018) Using enhancer-driven gene expression (EDGE) to generate viral vectors capable of driving transgene expression in particular cell types of targeted brain regions in any species. Society for Neuroscience conference, Neuroscience 2018 San Diego, USA . Society for Neuroscience; San Diego, USA. 2018-11-03 - 2018-11-07.
-
PosterRaveendran Nair, Rajeevkumar; Blankvoort, Stefan; Kentros, Clifford. (2018) Viruses made with entorhinal cortex-specific (EC) enhancers enable transgene expression restricted to particular EC celltypes in two species of wildtype animals. FENS Forum 2018, Berlin, Germany. . FENS; Berlin, Germany. 2018-07-07 - 2018-07-11.
2014
-
Academic lectureÅmellem, Ingrid; Raveendran Nair, Rajeevkumar; Cnops, Vanja; Thanawalla, Ayesha; Tashiro, Ayumu. (2014) NMDA receptors in dentate granule cells regulate adult neurogenesis and are involved in neurogenesis dependent behavioural tasks. The 2nd National PhD Conference in Neuroscience . The Norwegian Research School in Neuroscience (NRSN); Stiklestad. 2014-09-22 - 2014-09-24.