Rajeevkumar Nair Raveendran
Rajeevkumar Nair Raveendran
Manager/Researcher Viral Vector Core, Kavli Institute/CNC
rajeevkumar.r.nair@ntnu.no
About
Currently, Core Manager/Researcher at the Viral Vector Core (VVC), Kavli Institute for Systems Neuroscience/CNC, NTNU. Viral Vector Core
PhD in Biotechnology from Rajiv Gandhi Centre for Biotechnology, Kerala, India. Thesis title: ‘Structure-Function relationships in the interactions between Calcium/calmodulin dependent protein kinase type II (CaMKII) and N-methyl-D-aspartate receptor (NMDAR) subunits’. After PhD, I joined Bramham group, UiB, Norway as Post Doctoral Fellow/Researcher (2006-2010, studying the post-translational modifications of another memory-associated protein Arc/Arg3.1). Later, I joined Tashiro group (2010-2013, investigating the role of NMDA receptors in adult-neurogenesis) and Kentros group (2013-2018, developing cell type-specific viral vectors) at Kavli Institute for Systems Neuroscience/CNC, NTNU as Post Doctoral Fellow/Researcher. Google scholar profile
Passionate in understanding the secrets of brain, interested in creating novel molecular tools, and designing & creating viral vectors to deliver genes inside the cells in a petriplate to complex mammalian brains. A Science enthusiast interested in writing blogs for communicating Science to general audience. Scientific blogs
Management Committee member representing Norway for COST Action (CA21113- Genome Editing to Treat Humans Diseases).
Publications
2022
- Bauer, Ulrich Stefan; Fiskum, Vegard; Nair Raveendran, Rajeevkumar; Wijdeven, Rosanne Francisca van de; Kentros, Clifford; Sandvig, Ioanna; Sandvig, Axel. (2022) Validation of Functional Connectivity of Engineered Neuromuscular Junction With Recombinant Monosynaptic Pseudotyped ΔG-Rabies Virus Tracing. Frontiers in Integrative Neuroscience. volum 16.
- Jacobsen, R. Irene; Nair Raveendran, Rajeevkumar; Obenhaus, Horst-Andreas; Donato, Flavio; Slettmoen, Torstein; Moser, May-Britt; Moser, Edvard Ingjald. (2022) All-viral tracing of monosynaptic inputs to single birthdate-defined neurons in the intact brain. Cell reports. Methods. volum 2 (5).
- Kobro-Flatmoen, Asgeir; Battistin, Claudia; Nair Raveendran, Rajeevkumar; Bjorkli, Christiana; Skender, Belma; Kentros, Clifford; Gouras, Gunnar K; Witter, Menno. (2022) Lowering levels of reelin in entorhinal cortex layer II-neurons results in lowered levels of intracellular amyloid-β. bioRxiv.
2021
- Nigro, Maximiliano Jose; Kirikae, Hinaco; Kjelsberg, Kasper; Nair Raveendran, Rajeevkumar; Witter, Menno P.. (2021) Not All That Is Gold Glitters: PV-IRES-Cre Mouse Line Shows Low Efficiency of Labeling of Parvalbumin Interneurons in the Perirhinal Cortex. Frontiers in Neural Circuits. volum 15.
- Nigro, Maximiliano Jose; Kirikae, Hinako; Kjelsberg, Kasper; Nair Raveendran, Rajeevkumar; Witter, Menno. (2021) Not all that is gold glitters: PV-IRES-Cre mouse line shows low efficiency of labeling of parvalbumin interneurons in the perirhinal cortex. BioRxiv.
- Ohara, Shinya; Blankvoort, Stefan; Nair Raveendran, Rajeevkumar; Nigro, Maximiliano Jose; Nilssen, Eirik Stamland; Kentros, Clifford; Witter, Menno. (2021) Local projections of layer Vb-to-Va are more prominent in lateral than in medial entorhinal cortex. eLIFE.
- Åmellem, Ingrid; Yovianto, Glen; Tarng Chong, Hai; Nair Raveendran, Rajeevkumar; Cnops, Vanja; Thanawalla, Ayesha; Tashiro, Ayumu. (2021) Role of NMDA receptors in adult neurogenesis and normal development of the dentate gyrus. eNeuro.
2020
- Madhavan, Mayadevi; G.Mohanan, Archana; Sarah Jacob, Reena; Gunasekaran, Sowmya; Nair Raveendran, Rajeevkumar; Ramakrishnapillai V, Omkumar. (2020) Glu60 of α-Calcium/calmodulin dependent protein kinase II mediates crosstalk between the regulatory T-site and protein substrate binding region of the active site. Archives of Biochemistry and Biophysics. volum 685.
- Nair Raveendran, Rajeevkumar; Blankvoort, Stefan; Donate Lagartos, Maria Jose; Kentros, Clifford. (2020) Enhancer-Driven Gene Expression (EDGE) Enables the Generation of Viral Vectors Specific to Neuronal Subtypes. iScience. volum 23 (3).
2019
- Bauer, Ulrich Stefan; van de Wijdeven, Rosanne Francisca; Nair Raveendran, Rajeevkumar; Fiskum, Vegard; Kentros, Clifford; Sandvig, Ioanna; Sandvig, Axel. (2019) Modelling functional human neuromuscular junctions in a differentially-perturbable microfluidic environment, validated through recombinant monosynaptic pseudotyped ΔG-rabies virus tracing. BioRxiv.
2018
- Nair Raveendran, Rajeevkumar; Renganathan Chandrika, Arunkumar; Steephan, Mathew; Sudarsana Devi, Suma Priya; Kumar, Mantosh; Paul, Soumya; Madhavan, Mayadevi; Ramakrishnapillai V, Omkumar. (2018) A simple end-point assay for calcium channel activity. Cell Calcium. volum 74.
- Nilssen, Eirik Stamland; Jacobsen, Bente; Nair Raveendran, Rajeevkumar; Fjeld, Gunhild; Blankvoort, Stefan; Kentros, Clifford; Witter, Menno. (2018) Inhibitory Connectivity Dominates the Fan Cell Network in Layer II of Lateral Entorhinal Cortex. Journal of Neuroscience. volum 38 (45).
2017
- Myrum, Craig; Soule, Jonathan; Bittins, Margarethe; Cavagnini, Kyle; Goff, Kevin; Ziemek, Silje Karina; Eriksen, Maria Steene; Patil, Sudarshan; Szum, Adrian; Nair Raveendran, Rajeevkumar; Bramham, Clive R.. (2017) Arc interacts with the integral endoplasmic reticulum protein, calnexin. Frontiers in Cellular Neuroscience. volum 11:294.
- Nair Raveendran, Rajeevkumar; Patil, Sudarshan; Tiron, Adrian; Kanhema, Tambudzai; Panja, Debabrata; Schiro, Lars Erik; Parobczak, Kamil; Wilczynski, Grzegorz M; Bramham, Clive R.. (2017) Dynamic Arc SUMOylation and selective interaction with F-actin-binding protein Drebrin A in LTP consolidation in vivo. Frontiers in Synaptic Neuroscience. volum 9:8 (MAY).
2015
- Hall, Malgorzata H.; Magalska, Adriana; Malinowska, Monika; Ruszczycki, Blazej; Czaban, Iwona; Patel, Satyam; Ambrozek-Latecka, Magdalena; Zolocinska, Ewa; Broszkiewicz, Hanna; Parobczak, Kamil; Nair Raveendran, Rajeevkumar; Rylski, Marcin; Pawlak, Robert; Bramham, Clive R.; Wilczynski, Grzegorz M. (2015) Localization and regulation of PML bodies in the adult mouse brain. Brain Structure and Function. volum Published ahead of print.
2010
- Bramham, Clive R. Evjen; Alme, Maria Nordheim; Bittins, Margarethe; Kuipers, Sjoukje; Nair, Rajeevkumar R; Pai, Balagopal Sreenivasa; Panja, Debabrata; Schubert, Manja; Soule, Jonathan; Tiron, Adrian; Wibrand, Karin. (2010) The Arc of synaptic memory. Experimental Brain Research. volum 200 (2).
2009
- Bramham, Clive R. Evjen; Panja, Debabrata; Tiron, Adrian; Nair, Rajeevkumar R; Wibrand, Karin; Kuipers, S. (2009) Arc/Arg3.1 synthesis and control of LTp consolidation in the adult dentate gyrus in vivo. European Neuropsychopharmacology. volum 19.
- Nair Raveendran, Rajeevkumar; Sudarsana Devi, Suma Priya; Madhavan, Mayadevi; Mathew, Steephan; Thankayyan R., Santhoshkumar; John, Cheriyan; Rajendran, Sanalkumar; Jackson, James; Ramakrishnapillai V, Omkumar. (2009) Phosphorylation status of the NR2B subunit of NMDA receptor regulates its interaction with calcium/calmodulin‐dependent protein kinase II. Journal of Neurochemistry. volum 110.
Journal publications
- Bauer, Ulrich Stefan; Fiskum, Vegard; Nair Raveendran, Rajeevkumar; Wijdeven, Rosanne Francisca van de; Kentros, Clifford; Sandvig, Ioanna; Sandvig, Axel. (2022) Validation of Functional Connectivity of Engineered Neuromuscular Junction With Recombinant Monosynaptic Pseudotyped ΔG-Rabies Virus Tracing. Frontiers in Integrative Neuroscience. volum 16.
- Jacobsen, R. Irene; Nair Raveendran, Rajeevkumar; Obenhaus, Horst-Andreas; Donato, Flavio; Slettmoen, Torstein; Moser, May-Britt; Moser, Edvard Ingjald. (2022) All-viral tracing of monosynaptic inputs to single birthdate-defined neurons in the intact brain. Cell reports. Methods. volum 2 (5).
- Kobro-Flatmoen, Asgeir; Battistin, Claudia; Nair Raveendran, Rajeevkumar; Bjorkli, Christiana; Skender, Belma; Kentros, Clifford; Gouras, Gunnar K; Witter, Menno. (2022) Lowering levels of reelin in entorhinal cortex layer II-neurons results in lowered levels of intracellular amyloid-β. bioRxiv.
- Nigro, Maximiliano Jose; Kirikae, Hinaco; Kjelsberg, Kasper; Nair Raveendran, Rajeevkumar; Witter, Menno P.. (2021) Not All That Is Gold Glitters: PV-IRES-Cre Mouse Line Shows Low Efficiency of Labeling of Parvalbumin Interneurons in the Perirhinal Cortex. Frontiers in Neural Circuits. volum 15.
- Nigro, Maximiliano Jose; Kirikae, Hinako; Kjelsberg, Kasper; Nair Raveendran, Rajeevkumar; Witter, Menno. (2021) Not all that is gold glitters: PV-IRES-Cre mouse line shows low efficiency of labeling of parvalbumin interneurons in the perirhinal cortex. BioRxiv.
- Ohara, Shinya; Blankvoort, Stefan; Nair Raveendran, Rajeevkumar; Nigro, Maximiliano Jose; Nilssen, Eirik Stamland; Kentros, Clifford; Witter, Menno. (2021) Local projections of layer Vb-to-Va are more prominent in lateral than in medial entorhinal cortex. eLIFE.
- Åmellem, Ingrid; Yovianto, Glen; Tarng Chong, Hai; Nair Raveendran, Rajeevkumar; Cnops, Vanja; Thanawalla, Ayesha; Tashiro, Ayumu. (2021) Role of NMDA receptors in adult neurogenesis and normal development of the dentate gyrus. eNeuro.
- Madhavan, Mayadevi; G.Mohanan, Archana; Sarah Jacob, Reena; Gunasekaran, Sowmya; Nair Raveendran, Rajeevkumar; Ramakrishnapillai V, Omkumar. (2020) Glu60 of α-Calcium/calmodulin dependent protein kinase II mediates crosstalk between the regulatory T-site and protein substrate binding region of the active site. Archives of Biochemistry and Biophysics. volum 685.
- Nair Raveendran, Rajeevkumar; Blankvoort, Stefan; Donate Lagartos, Maria Jose; Kentros, Clifford. (2020) Enhancer-Driven Gene Expression (EDGE) Enables the Generation of Viral Vectors Specific to Neuronal Subtypes. iScience. volum 23 (3).
- Bauer, Ulrich Stefan; van de Wijdeven, Rosanne Francisca; Nair Raveendran, Rajeevkumar; Fiskum, Vegard; Kentros, Clifford; Sandvig, Ioanna; Sandvig, Axel. (2019) Modelling functional human neuromuscular junctions in a differentially-perturbable microfluidic environment, validated through recombinant monosynaptic pseudotyped ΔG-rabies virus tracing. BioRxiv.
- Nair Raveendran, Rajeevkumar; Renganathan Chandrika, Arunkumar; Steephan, Mathew; Sudarsana Devi, Suma Priya; Kumar, Mantosh; Paul, Soumya; Madhavan, Mayadevi; Ramakrishnapillai V, Omkumar. (2018) A simple end-point assay for calcium channel activity. Cell Calcium. volum 74.
- Nilssen, Eirik Stamland; Jacobsen, Bente; Nair Raveendran, Rajeevkumar; Fjeld, Gunhild; Blankvoort, Stefan; Kentros, Clifford; Witter, Menno. (2018) Inhibitory Connectivity Dominates the Fan Cell Network in Layer II of Lateral Entorhinal Cortex. Journal of Neuroscience. volum 38 (45).
- Myrum, Craig; Soule, Jonathan; Bittins, Margarethe; Cavagnini, Kyle; Goff, Kevin; Ziemek, Silje Karina; Eriksen, Maria Steene; Patil, Sudarshan; Szum, Adrian; Nair Raveendran, Rajeevkumar; Bramham, Clive R.. (2017) Arc interacts with the integral endoplasmic reticulum protein, calnexin. Frontiers in Cellular Neuroscience. volum 11:294.
- Nair Raveendran, Rajeevkumar; Patil, Sudarshan; Tiron, Adrian; Kanhema, Tambudzai; Panja, Debabrata; Schiro, Lars Erik; Parobczak, Kamil; Wilczynski, Grzegorz M; Bramham, Clive R.. (2017) Dynamic Arc SUMOylation and selective interaction with F-actin-binding protein Drebrin A in LTP consolidation in vivo. Frontiers in Synaptic Neuroscience. volum 9:8 (MAY).
- Hall, Malgorzata H.; Magalska, Adriana; Malinowska, Monika; Ruszczycki, Blazej; Czaban, Iwona; Patel, Satyam; Ambrozek-Latecka, Magdalena; Zolocinska, Ewa; Broszkiewicz, Hanna; Parobczak, Kamil; Nair Raveendran, Rajeevkumar; Rylski, Marcin; Pawlak, Robert; Bramham, Clive R.; Wilczynski, Grzegorz M. (2015) Localization and regulation of PML bodies in the adult mouse brain. Brain Structure and Function. volum Published ahead of print.
- Bramham, Clive R. Evjen; Alme, Maria Nordheim; Bittins, Margarethe; Kuipers, Sjoukje; Nair, Rajeevkumar R; Pai, Balagopal Sreenivasa; Panja, Debabrata; Schubert, Manja; Soule, Jonathan; Tiron, Adrian; Wibrand, Karin. (2010) The Arc of synaptic memory. Experimental Brain Research. volum 200 (2).
- Bramham, Clive R. Evjen; Panja, Debabrata; Tiron, Adrian; Nair, Rajeevkumar R; Wibrand, Karin; Kuipers, S. (2009) Arc/Arg3.1 synthesis and control of LTp consolidation in the adult dentate gyrus in vivo. European Neuropsychopharmacology. volum 19.
- Nair Raveendran, Rajeevkumar; Sudarsana Devi, Suma Priya; Madhavan, Mayadevi; Mathew, Steephan; Thankayyan R., Santhoshkumar; John, Cheriyan; Rajendran, Sanalkumar; Jackson, James; Ramakrishnapillai V, Omkumar. (2009) Phosphorylation status of the NR2B subunit of NMDA receptor regulates its interaction with calcium/calmodulin‐dependent protein kinase II. Journal of Neurochemistry. volum 110.