Trond Peder Flaten

Høgskoleringen 5, Realfagbygget * E2-118

trond.p.flaten@ntnu.no

Research areas

A key word for my research activities and fields of interest is multidisciplinarity. Broadly speaking, the external environment's possible influences on human health is my main area. The biochemical, physiological, and toxicological roles of trace elements in medicine and biology, and their possible roles in disease, is a focus of study. A particular interest is the possible roles of metals and trace elements in neurodegenerative diseases; Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis. In addition, drinking water and environmental toxins other than metals and trace elements, and other types of diseases, are studied. Also, studies related to the behaviour of trace elements in nature – air, water, soil and animals – are carried out. I am also doing epidemiological studies, currently in cooperation with the Department of Public Health and General Practice at NTNU, and have been editor for the journal Norsk Epidemiologi (Norwegian Journal of Epidemiology, http://www.ntnu.no/ojs/index.php/norepid) since 1995.

On my initiative, in the 3. wave of the Nord-Trøndelag health study (HUNT), 2006-2008, one of the 5 blood samples drawn from each participant is devoted to the analysis of trace elements and other compounds which may indicate environmental exposure. The first Ph.D. candidate under my supervision using these samples, will defend her thesis in 2016. The thesis consists of a large study of normal values of trace elements in the population, and 2 case-control studies of trace elements in type 2 diabetes. The main analytical tool in these and other studies is our Department's HR-ICP-MS instrument – the most powerful analytical technique currently available for multielement analysis at low concentrations.

Scientific, academic and artistic work

A selection of recent journal publications, artistic productions, books, including book and report excerpts. See all publications in the database

Journal publications

Farkas, Julia; Salaberria, Iurgi; Styrishave, Bjarne; Stanková, Radka; Ciesielski, Tomasz Maciej; Olsen, Anders Johny; Posch, Wilfried; Flaten, Trond Peder; Krøkje, Åse; Salvenmoser, Willi; Jenssen, Bjørn Munro. (2017) Exposure of juvenile turbot (Scophthalmus maximus) to AgNP-EE2 mixtures: Implications on contaminant bioavailability and plasma steroid hormone levels. Environmental Pollution. vol. 220.
Hansen, Ailin Falkmo; Simic, Anica; Åsvold, Bjørn Olav; Romundstad, Pål Richard; Midthjell, Kristian; Syversen, Tore; Flaten, Trond Peder. (2017) Trace Elements in Early Phase Type 2 Diabetes Mellitus – a Population-based Study. The HUNT Study in Norway. Journal of Trace Elements in Medicine and Biology. vol. 40.
Simic, Anica; Hansen, Ailin Falkmo; Åsvold, Bjørn Olav; Romundstad, Pål Richard; Midthjell, Kristian; Syversen, Tore; Flaten, Trond Peder. (2017) Trace element status in patients with type 2 diabetes in Norway: The HUNT3 Survey. Journal of Trace Elements in Medicine and Biology. vol. 41.
Brzezicha-Cirocka, Justyna; Grembecka, Małgorzata; Ciesielski, Tomasz Maciej; Flaten, Trond Peder; Szefer, Piotr. (2016) Evaluation of Macro- and Microelement Levels in Black Tea in View of Its Geographical Origin. Biological Trace Element Research. vol. 176.
Weggeberg, Hanne; Føreland, Solveig; Buhagen, Morten; Hilt, Bjørn; Flaten, Trond Peder. (2016) Multi-element analysis of airborne particulate matter from different work tasks during subsea tunnel rehabilitation work. Journal of Occupational and Environmental Hygiene. vol. 13 (10).
Aspli, Klaus Thanke; Flaten, Trond Peder; ROOS, PER; Holmøy, Trygve; Skogholt, Jon Henry; Aaseth, Jan. (2015) Iron and copper in progressive demyelination: New lessons from Skogholt’s disease. Journal of Trace Elements in Medicine and Biology. vol. 31.
Dahl, Cecilie; Søgaard, Anne-Johanne; Tell, Grethe Seppola; Forsen, Lisa; Flaten, Trond Peder; Hongve, Dag; Omsland, Tone Kristin; Holvik, Kristin; Meyer, Haakon E; Aamodt, Geir. (2015) Population data on calcium in drinking water and hip fracture: An association may depend on other minerals in water. A NOREPOS study. Bone. vol. 81.
Dusek, Petr; ROOS, PER; Litwin, Tomasz; Schneider, Susanne A.; Flaten, Trond Peder; Aaseth, Jan. (2015) The neurotoxicity of iron, copper and manganese in Parkinson's and Wilson's diseases. Journal of Trace Elements in Medicine and Biology. vol. 31.
Nordløkken, Marit; Berg, Torunn; Flaten, Trond Peder; Steinnes, Eiliv. (2015) Essential and non-essential elements in natural vegetation in southern Norway: Contribution from different sources. Science of the Total Environment. vol. 502.
Simic, Anica; Flaten, Trond Peder. (2015) Do trace elements play a role in type 2 diabetes?. Kjemi.
Simic, Anica; Hansen, Ailin Falkmo; Åsvold, Bjørn Olav; Romundstad, Pål Richard; Syversen, Tore; Midthjell, Kristian; Flaten, Trond Peder. (2015) Ca, Mg and Fe blood levels in diabetic patients differ with disease duration and glucose-lowering treatment. Journal of Trace Elements in Medicine and Biology. vol. 32.
Simic, Anica; Syversen, Tore; Hansen, Ailin Falkmo; Åsvold, Bjørn Olav; Romundstad, Pål Richard; Midthjell, Kristian; Flaten, Trond Peder. (2015) Trace elements in whole blood in the general population in Nord-Trøndelag County, Norway – the HUNT3 Survey. Journal of Trace Elements in Medicine and Biology. vol. 32.
Dahl, Cecilie; Søgaard, Anne Johanne; Tell, Grethe Seppola; Flaten, Trond Peder; Hongve, Dag; Omsland, Tone Kristin; Holvik, Kristin; Meyer, Haakon E; Aamodt, Geir. (2014) Is copper in drinking water related to risk of hip fracture? And could a possible protective associationbetween calcium and hip fracture be modified by copper?. Norsk Epidemiologi. vol. 24.
Dahl, Cecilie; Søgaard, Anne-Johanne; Tell, Grethe S; Flaten, Trond Peder; Hongve, Dag; Omsland, Tone Kristin; Holvik, Kristin; Meyer, Haakon E; Aamodt, Geir. (2014) Do cadmium, lead, and aluminum in drinking water increase the risk of hip fractures? A NOREPOS study. Biological Trace Element Research. vol. 157 (1).
Hansen, Ailin Falkmo; Simic, Anica; Åsvold, Bjørn Olav; Romundstad, Pål Richard; Syversen, Tore; Midthjell, Kristian; Flaten, Trond Peder. (2014) Trace elements in undiagnosed type 2 diabetes mellitus (HUNT3). Toxicology Letters. vol. 229.
Simic, Anica; Hansen, Ailin Falkmo; Åsvold, Bjørn Olav; Romundstad, Pål Richard; Syversen, Tore; Midthjell, Kristian; Flaten, Trond Peder. (2014) Do trace element differences in diabetic patients persist with time? The HUNT3 Survey. Toxicology Letters. vol. 229.
Simic, Anica; Hansen, Ailin Falkmo; Åsvold, Bjørn Olav; Romundstad, Pål Richard; Syversen, Tore; Midthjell, Kristian; Flaten, Trond Peder. (2014) Trace elements and type 2 diabetes - two case-control studies in HUNT3. Norsk Epidemiologi, Supplement. vol. 24.
Dahl, Cecilie; Søgaard, Anne Johanne; Tell, Grethe S; Flaten, Trond Peder; Krogh, Truls; Aamodt, Geir. (2013) Is the quality of drinking water a risk factor for self-reported forearm fractures? Cohort of Norway. Osteoporosis International. vol. 24 (2).
Dahl, Cecilie; Søgaard, Anne-Johanne; Tell, Grethe S; Flaten, Trond Peder; Hongve, Dag; Omsland, Tone Kristin; Holvik, Kristin; Meyer, Haakon E; Aamodt, Geir. (2013) Nationwide data on municipal drinking water and hip fracture: Could calcium and magnesium be protective? A NOREPOS study. Bone. vol. 57 (1).
ROOS, PER; Vesterberg, Olof; Syversen, Tore; Flaten, Trond Peder; Nordberg, Monica. (2013) Metal Concentrations in Cerebrospinal Fluid and Blood Plasma from Patients with Amyotrophic Lateral Sclerosis. Biological Trace Element Research. vol. 151 (2).