Gold catalysed cyclizations of 1,6-diynes

Gold catalysed cyclizations of 1,6-diynes

The Fiksdahl group has developed [1-3] a number of novel cyclization reactions from different 1,6-diyne substrates, affording a great variety of new interesting highly functionalised  (poly)cyclic products:

Aims;
-    study gold(I) catalyzed cyclization reactions of 1,6-diynes:

-    investigate the ability of 1,6-diynes to undergo tandem cyclisation:

1. Sperger; C.; Fiksdahl, A. Organic Letters 11 (2009) 2449.
2. Sperger, A. Fiksdahl J. Org. Chem 75 (2010) 4542.
3. Sperger, C.; Strand; L. H. S.; Fiksdahl, A. Tetrahedron 66 (2010) 7749.