Course content

The course deals with basic principles for protein structures, and for structure – function relationships, properties of amino acids, intramolecular forces, secondary structure elements, motifs, protein folds, classification of proteins based on 3D structure, in addition to some biophysical principles for folding of proteins. A number of protein classes will be discussed in more detail; DNA binding proteins, membrane bound proteins, proteins in the immune system, enzymes, virus proteins and fibrous proteins. A brief introduction to some methods for 3D structure determination will also be given, along with tools and methods for bioinformatics analysis of protein structures and molecular modelling.

Learning outcome

The students will gain insight into general principles for protein 3D-structures and the relation between protein structure and function.

Learning methods and activities

The teaching is based on lecture for each new theme. The students are additionally offered the possibility to solve problems under guidance, while a set of PC and internet based excersises are mandatory for the course. The course will be given in English if necessary.

Compulsory assignments

• Exercises

Recommended previous knowledge

Basic knowledge in general and organic chemistry, biochemistry and cell biology is recommended.

Course materials

Branden & Tooze: “Introduction to Protein Structure.” Second edition. Garland Publishing., Inc. 1999.
Some additional syllabus will be given at the beginning of the course

Credit reductions