course-details-portlet

KJ1021 - Organic Chemistry Basic Course w/o Lab

About

Examination arrangement

Examination arrangement: School exam
Grade: Letter grades

Evaluation Weighting Duration Grade deviation Examination aids
School exam 100/100 4 hours HJELPEMIDD

Course content

Basic organic chemical concepts, such as chemical structures and nomenclature, physical properties, stereochemistry and relationship between structure and reactivity will be presented. Reaction mechanisms will be presented to give insight in chemical transformations. Alkanes and cycloalkanes: Conformations and cis-trans stereoisomers. Stereochemistry: Geometric isomers, conformation isomers, configuration isomers and pro-chirality. Absolute and relative configuration, R/S notational system for chiral C-atoms, optical activity (specific rotation), enantiomers, diastereomers, meso compounds, three-dimensional projections of molecule´s atoms, stereochemistry in chemical reactions. Alcohols and alkyl halides: Substitution (SN1/SN2), elimination (E1/E2), potential energy diagrams for multiple step reactions, carbocations and rearrangements. Nucleophilic substitution (SN2): Nucleophilic reagents, nucleophilicity versus basicity, solvent effects, leaving group, functionalization and stereochemistry. Structure and preparation of alkenes: Elimination reactions. Addition reactions of alkenes: (i) Hydrogenation, (ii) electrophilic addition of hydrogen halides (Markovnikov's rule and mechanism), (iii) acid-catalyzed hydration, (iv) hydroboration-oxidation to alcohols (anti-Markovinkov), (v) epoxidation. Alkynes: Preparation, acid-base properties, alkylation of terminal alkynes. Addition reactions of alkynes. Radical reactions: (i) radical intermediates, (ii) radical halogenation of alkanes, allylic and benzylic compounds. Alcohols: Preparation by (i) reduction of carbonyl compounds, (ii) ring opening of epoxides, (iii) dihydroxylation of alkenes. Reactions of alcohols: (i) Preparation of ethers, (ii) preparation of esters and (iii) oxidation to aldehyde/carboxylic acid/ketone. Grignard reagents and organolitium (organometallic compounds): Preparation, reactivity and reactions (base and addition to carbonyl compounds). Conjugation in alkadienes and allylic systems, allylic carbocations, resonance (electron delocalization), stability, isolated dienes, conjugated dienes, cumulated dienes. Conjugated dienes: (i) Preparation, (ii) addition of hydrogen halide, The Diels-Alder reaction. Arenes and aromaticity. Reactions of arenes: Electrophilic aromatic substitution. Radical halogenation of alkylbenzenes. Aldehydes and ketones: (i) Structure and reactivity, (ii) The Wittig reaction, (iii) preparation of imine, (iv) acetal formation, (v) enols and enolates, (vi) alkylation of enolates, (vii) aldol condensation. Carboxylic acids: (i) Acidity, (ii) preparation and (iii) reactions (ester formation). Carboxylic acid derivatives: (i) Esters, (ii) acid anhydrides, (iii) acid halides. Hydrolysis of carboxylic acid derivatives.

Sustainability in the preparation of organic compounds will be demonstrated in the lectures applying "Green chemical" principles. Examples may include: (i) atom economy and efficiency, (ii) use of less hazardous and toxic chemicals, (iii) preferred use of renewable raw materials, (iv) shorter syntheses (avoid derivatization), (v) catalytic rather than stoichiometric reagents.

Learning outcome

After completing this course the student will, in relation to the content of the subject: - be able to understand and communicate nomenclature and structure of organic chemical compounds - know basic principles for reactions in organic chemistry - be able to account for and derive mechanistic features of the reactions - be able to predict competing reactions - be able to name central reactions - have a basic knowledge of how functional groups affect electron density, properties and reactivity in organic compounds - be able to estimate pKa values for carboxylic acids, amines, alcohols and ketones in the presence of different functional groups. Through the course, the student will gain awarness regarding the importance of choosing sustainable solutions and possible challenges related to organic synthetic chemistry.

Learning methods and activities

KJ1021 consists of lectures and theoretical exercises. 67% of the exercises must be approved in order to attend the final exam (8 of 12 exercises). Expected work load in the course is 200-225 hours.

Information about the time for compulsory activity in the semester will be announced by the subject responsible at the start of the semester.

Compulsory assignments

  • Approved exercises

Further on evaluation

The final written examination (4 hours) is evaluated and graded by letter. Exam during a term without lectures in this course, the examination may be changed from written to oral.

Permitted tools at exam: At the exam may be used approved calculators only. Other electronic devices (MP3, iPod, Mobile Phones and the like) are not allowed at the exam. Molecular models are permitted. No other written or printed material is allowed.

Required previous knowledge

The course is based on KJ1000 or KJ1002.

Course materials

Solomoms, Fryhle, Snyder "Organic chemistry", 12 ed.

More on the course

No

Facts

Version: 1
Credits:  7.5 SP
Study level: Foundation courses, level I

Coursework

Term no.: 1
Teaching semester:  SPRING 2024

Language of instruction: Norwegian

Location: Trondheim

Subject area(s)
  • Chemistry
Contact information
Course coordinator:

Department with academic responsibility
Department of Chemistry

Examination

Examination arrangement: School exam

Term Status code Evaluation Weighting Examination aids Date Time Examination system Room *
Autumn ORD School exam 100/100 HJELPEMIDD 2023-11-24 09:00 INSPERA
Room Building Number of candidates
SL310 blå sone Sluppenvegen 14 7
SL323 Sluppenvegen 14 1
Spring ORD School exam 100/100 HJELPEMIDD 2024-05-27 15:00 INSPERA
Room Building Number of candidates
SL311 Sluppenvegen 14 100
  • * The location (room) for a written examination is published 3 days before examination date. If more than one room is listed, you will find your room at Studentweb.
Examination

For more information regarding registration for examination and examination procedures, see "Innsida - Exams"

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