KJ8059 - Chromatography, Advanced Course


Examination arrangement

Examination arrangement: Written examination
Grade: Passed/Failed

Evaluation form Weighting Duration Examination aids Grade deviation
Written examination 100/100 4 hours C

Examination arrangement

Examination arrangement: Home examination
Grade: Passed/Failed

Evaluation form Weighting Duration Examination aids Grade deviation
Home examination 100/100 4 hours

Course content

Techniques of, mostly chromatography-related, modern analytical separation and quantification methods are presented.
Topics presented are a.o. chromatographic theory, including the solvation parameter model of retention; some advanced aspects of liquid chromatography (HPLC) and gas chromatography (GC); 2-dimensional chromatography (coupled methods chromatography-chromatography); 'tandem techniques' based on on-line coupling of separation methods and spectrometry; mass spectrometry, with focus on applications in connection with analytical separation methods.
Other relevant topics can be included, such as capillary electromigration separation methods, supercritical fluid chromatography, stereoisomer separation and preparative chromatography techniques. Students choose two of them for self-studying, as an elective part of the final examination.
Laboratory exercises apply some of these concepts, a.o. an on-line coupled method. Exercises provide the possibility for some repetition of basic concepts, discussions of relevant applications from current research papers and presentation of special topics.
This course has nearly the same content as, and is taught together with, KJ3059, except for the project work included in KJ8059, and some additional reading matter.

Learning outcome

At the end of the course a student should have:
- acquired the knowledge to explain the principles of a wide range of modern analytical methods of separation and quantitation;
- also knowledge about practical and technical aspects of these methods, and for some of them to have some experience with them at an advanced level;
- acquired knowledge on Quality Control and validation in connection with planning and performing chemical analyses;
- acquired the skills to evaluate strengths and limitations of different separation and detection techniques with respect to sample properties and to specific analytical problems;
- acquired the skills to find, choose and plan the use of suitable analytical separation techniques for actual advanced analytical problems based on a sound knowledge of the potentially relevant methods;
- acquired the skills to judge the quality of his/her own, or others', analytical results from analytical separation methods, and to evaluate the chosen operational procedures;
- acquired the skills to find, understand, and if necessary adapt to own requirements, published procedures, e.g. to locally available technical resources or to more modern practices;
- acquired the skills to use advanced analytical methods of separation and quantitation in an effective and reasonable way after only a minimum of practical teaching;
- acquired the general competence to deal with problems to be addressed and activities within the subfield of the course in an independent way;
- acquired the general competence to communicate and disseminate basic and/or technical knowledge in the subject area comprehensibly and adequately;
- acquired the general competence to independently update and expand his/her knowledge in an advanced area of science.

Learning methods and activities

Lectures (3 hours per week), exercises (1 hour per week), laboratory exercises (40 hours) and project work (25 hours). All laboratory exercise reports as well as the project work report must be approved in order to get access to the final examination. HSE instruction will be given to students that have not received such chromatography-specific information earlier (e.g. in KJ2053). This instruction is a prerequisite to get access to the lab. course. It is given before start-up of the laboratory activities, typically in October (time to be agreed on). nglish teaching by request. When lectures and exercises are given in English, the examination text can be given in English only (it is allowed answers in a Scandinavian language). For re-sit exam or exam during a term without lectures in this course, written examination may be changed to oral examination.

Compulsory assignments

  • Approved laboratory exercises
  • Approved project work

Further on evaluation

In case of a re-sit examination only the written exam is to be repeated.

Specific conditions

Exam registration requires that class registration is approved in the same semester. Compulsory activities from previous semester may be approved by the department.

Course materials

To be announced by us at the beginning of the course (possibly: C. F. Poole, The essence of chromatography, 1.edn., 2003, Elsevier, but also additional and/or alternative reading matter).

Credit reductions

Course code Reduction From To
KJ3059 7.5 01.09.2012
KJ3058 7.5 01.09.2012
KJ8058 7.5 01.09.2012
More on the course



Version: 1
Credits:  7.5 SP
Study level: Doctoral degree level


Term no.: 1
Teaching semester:  AUTUMN 2020

No.of lecture hours: 3
Lab hours: 5
No.of specialization hours: 4

Language of instruction: English, Norwegian

Location: Trondheim

Subject area(s)
  • Analytical Chemistry
  • Environmental Chemistry
  • Organic Chemistry
  • Biochemistry
  • Chemistry
Contact information
Course coordinator: Lecturer(s):

Department with academic responsibility
Department of Chemistry



Examination arrangement: Written examination

Term Status code Evaluation form Weighting Examination aids Date Time Digital exam Room *
Spring ORD Written examination 100/100 C 2021-06-10 09:00
Room Building Number of candidates

Examination arrangement: Home examination

Term Status code Evaluation form Weighting Examination aids Date Time Digital exam Room *
Autumn ORD Home examination 100/100

Release 2020-11-30

Submission 2020-11-30

Release 09:00

Submission 13:00

Room Building Number of candidates
  • * The location (room) for a written examination is published 3 days before examination date. If more than one room is listed, you will find your room at Studentweb.

For more information regarding registration for examination and examination procedures, see "Innsida - Exams"

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