Course - Metabolomics- Methods and Applications - MEDT8010
MEDT8010 - Metabolomics- Methods and Applications
About
Examination arrangement
Examination arrangement: Home examination
Grade: Passed/Failed
Evaluation | Weighting | Duration | Grade deviation | Examination aids |
---|---|---|---|---|
Hjemmeeksamen | 100/100 | 3 uker |
Course content
Metabolism is the set of chemical reactions that occur in living organisms in order to maintain life. Metabolomics is the systematic study of metabolic profiles in biological samples and tissues. It is the newest omics science, and a complementary tool to genomics and proteomics in systems biology.
The course gives an introduction to the use of metabolomics. The objectives are to give participants knowledge of advanced NMR and MS techniques, including hands-on experience with processing and analysis of such data, used in metabolomics.
Theoretical and practical aspects of these methods, including sample preparation, data acquisition, processing and further analysis will be discussed.
The course will also cover NMR and MS based metabolomics applied to various types of samples. Requirements, information content as well as strengths and limitations of metabolomics will be included.
The role of metabolomics in biological and medical research as well as clinical use will be illustrated.
Learning outcome
After completing the course, the student:
1 Should understand the principles of metabolomics.
2 Should be able to evaluate and apply the appropriate experimental design in a given metabolomics research question (including sample processing, choiche of methods and analytical strategies).
3 Should be able to apply advanced NMR and MS methods in metabolomics experiments.
4 Should be able to analyse and interpret NMR and MS data.
5 Should be able to critically evaluate metabolomics results and publications.
6 Should be able to write a review paper at international publication level about a chosen topic within metabolomics.
Learning methods and activities
Lectures, teamwork with relevant scientific papers and hands-on exercises. The course will be arranged with a minimum of 4 students.
The course will be held as an intensive course, 6 fully days distributed on two weeks. These weeks will either take place subsequently or be arranged a couple of weeks apart. Following activities will take place:
- lectures (32 hours)
- hands-on exercises (teamwork). Written reports/summaries from the exercises/teamwork will be requested(10 hours)
- laboratory exercises (16 hours)
- self study (130 hours)
- home exam
Participation in lectures, exercises and lab is obligatory, and a prerequisite to be allowed to deliver the home exam.
Compulsory assignments
- Lectures
- Lab
- Exercises
Recommended previous knowledge
Some basic experience in practical/theoretical high resolution magnetic resonance spectroscopy (NMR/MRS), gas/liquid chromatography (GC/LC) and mass spectrometry (MS).
Required previous knowledge
Master's Degree or similar. Medical students at The Student Research Programme. Candidates with a lower degree will be assessed individually.
Course materials
Teaching material will be found at It's learning.
No
Version: 1
Credits:
7.5 SP
Study level: Doctoral degree level
Term no.: 1
Teaching semester: AUTUMN 2015
Language of instruction: English
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- Biophysics and Medical Technology
- Bioinformatics
- Biochemistry
- Biomedical Engineering
- Biotechnology
- Medicine
- Medical Technology
- Beathe Sitter
- May-Britt Tessem
- Ola Dale
- Per Bruheim
- Siver Andreas Moestue
- Tone Frost Bathen
Department with academic responsibility
Department of Circulation and Medical Imaging
Examination
Examination arrangement: Home examination
- Term Status code Evaluation Weighting Examination aids Date Time Examination system Room *
- Autumn ORD Hjemme-eksamen 100/100
-
Room Building Number of candidates
- * The location (room) for a written examination is published 3 days before examination date. If more than one room is listed, you will find your room at Studentweb.
For more information regarding registration for examination and examination procedures, see "Innsida - Exams"