2025

• Dand, Nick; Stuart, Philip E.; Bowes, John; Ellinghaus, David; Nititham, Joanne; Saklatvala, Jake R.; Teder-Laving, Maris; Thomas, Laurent Francois; Traks, Tanel; Uebe, Steffen. (2025) GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets. Nature Communications
  Academic article

2024

• Helgeland, Øyvind; Vaudel, Marc; Sole-Navais, Pol; Flatley, Christopher; Juodakis, Julius; Bacelis, Jonas; Koløen, Ingvild L.; Knudsen, Gun Peggy Strømstad; Johansson, Bente Berg; Magnus, Per Minor. (2024) Correction to: Characterization of the genetic architecture of infant and early childhood body mass index (Nature Metabolism, (2022), 4, 3, (344-358), 10.1038/s42255-022-00549-1). Nature Metabolism
  Corrigendum

2023

• Lagou, Vasiliki; Jiang, Longda; Ulrich, Anna; Zudina, Liudmila; González, Karla Sofia Gutiérrez; Balkhiyarova, Zhanna; Faggian, Alessia; Maina, Jared G.; Chen, Shiqian; Todorov, Petar V.. (2023) GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification. Nature Genetics
  Academic article

2022

• Brumpton, Ben Michael; Graham, Sarah; Surakka, Ida; Skogholt, Anne Heidi; Løset, Mari; Fritsche, Lars G.; Wolford, Brooke; Zhou, Wei; Nielsen, Jonas Bille; Holmen, Oddgeir Lingaas. (2022) The HUNT study: A population-based cohort for genetic research. Cell Genomics
  Academic article
• Bahrami, Shahram; Hindley, Guy Frederick Lanyon; Winsvold, Bendik K S; O'Connell, Kevin Sean; Frei, Oleksandr; Shadrin, Alexey; Cheng, Weiqiu; Bettella, Francesco; Rødevand, Linn; Ødegaard, Ketil Joachim. (2022) Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools. Brain
  Academic article
• Helgeland, Øyvind; Vaudel, Marc; Sole-Navais, Pol; Flatley, Christopher; Juodakis, Julius; Bacelis, Jonas; Koløen, Ingvild; Knudsen, Gun Peggy Strømstad; Johansson, Bente Berg; Magnus, Per Minor. (2022) Characterization of the genetic architecture of infant and early childhood body mass index. Nature Metabolism
  Academic article

2021

• Freidin, Maxim B.; Tsepilov, Yakov A.; Stanaway, Ian B.; Meng, Weihua; Hayward, Caroline; Smith, Blair H.; Khoury, Samar; Parisien, Marc; Bortsov, Andrey; Diatchenko, Luda. (2021) Sex- and age-specific genetic analysis of chronic back pain. Pain
  Academic article
• Bianchini, Federico; Birkeland, Even; Bösl, Korbinian; Gade, Alexandra; Holmen, Oddgeir Lingaas; Hu, Xian; Johaadien, Rukaya Sarah; Matús, Kosut; Rothweiler, Ulli; Skogholt, Anne Heidi. (2021) BioMedData Deliverable D2.1 - Report on data management plan needs/gaps. Zenodo
  Research report

2020

• Nielsen, Jonas Bille; Rom, Oren; Surakka, Ida; Graham, Sarah E.; Zhou, Wei; Roychowdhury, Tanmoy; Fritsche, Lars; Taliun, Sarah Gagliano; Sidore, Carlo; Liu, Yuhao. (2020) Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease. Nature Communications
  Academic article

2019

• Rounge, Trine Ballestad; Lauritzen, Marianne; Erlandsen, Sten Even; Langseth, Hilde; Holmen, Oddgeir Lingaas; Gislefoss, Randi Elin. (2019) Ultralow amounts of DNA from long-term archived serum samples produce quality genotypes. European Journal of Human Genetics
  Academic article
• Lyngbakken, Magnus; Røsjø, Helge; Holmen, Oddgeir Lingaas; Dalen, Håvard; Hveem, Kristian; Omland, Torbjørn. (2019) Temporal changes in cardiac troponin i are associated with risk of cardiovascular events in the general population: The Nord-Trøndelag health study. Clinical Chemistry
  Academic article
• Justice, Anne E.; Karaderi, Tugce; Highland, Heather M.; Young, Kristin L.; Graff, Mariaelisa; Lu, Yingchang; Turcot, Valerie; Auer, Paul L.; Fine, Rebecca S.; Guo, Xiuqing. (2019) Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. Nature Genetics
  Academic article
• Turcot, Valérie; Lu, Yingchang; Highland, Heather M.; Schurmann, Claudia; Justice, Anne E.; Fine, Rebecca S.; Bradfield, Jonathan P.; Esko, Tõnu; Giri, Ayush; Graff, Mariaelisa. (2019) Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (Nature Genetics, (2018), 50, 1, (26-41), 10.1038/s41588-017-0011-x). Nature Genetics
  Corrigendum
• Helgeland, Øyvind; Vaudel, Marc; Juliusson, Petur Benedikt; Holmen, Oddgeir Lingaas; Juodakis, Julius; Bacelis, Jonas; Jacobsson, Bo; Lindekleiv, Haakon; Hveem, Kristian; Lie, Rolv T.. (2019) Genome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth. Nature Communications
  Academic article

2018

• Løset, Mari; Modalsli, Ellen Heilmann; Snekvik, Ingrid; Solvin, Åshild Øksnevad; Holmen, Oddgeir Lingaas; Gabrielsen, Maiken Elvestad; Fritsche, Lars; Zhou, Wei; Nielsen, Jonas Bille; Brumpton, Ben Michael. (2018) 743 HUNTing for genes that affect inflammatory skin disease in 4,071 cases and 40,430 controls. Journal of Investigative Dermatology
  Conference abstract
• Turcot, Valérie; Helgeland, Øyvind; Holmen, Oddgeir Lingaas; Johansson, Stefan; Njølstad, Pål Rasmus; Loos, Ruth J.F.. (2018) Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. Nature Genetics
  Corrigendum
• Sigurdardottir, Fjola Dogg; Lyngbakken, Magnus Nakrem; Holmen, Oddgeir Lingaas; Dalen, Håvard; Hveem, Kristian; Røsjø, Helge; Omland, Torbjørn. (2018) Relative prognostic value of cardiac troponin I and C-reactive protein in the general population (from the Nord-Trøndelag Health [HUNT] Study). American Journal of Cardiology
  Academic article
• Nielsen, Jonas B.; Fritsche, Lars; Zhou, Wei; Teslovich, Tanya M.; Holmen, Oddgeir Lingaas; Gustafsson, Stefan; Gabrielsen, Maiken Elvestad; Schmidt, Ellen M.; Beaumont, Robin; Wolford, Brooke N.. (2018) Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development. American Journal of Human Genetics
  Academic article
• Nielsen, Jonas B.; Thorolfsdottir, Rosa B.; Fritsche, Lars; Zhou, Wei; Skov, Morten W.; Graham, Sarah E.; Herron, Todd J.; McCarthy, Shane; Schmidt, Ellen M.; Sveinbjornsson, Gardar. (2018) Biobank-driven genomic discovery yields new insight into atrial fibrillation biology. Nature Genetics
  Academic article
• Thorolfsdottir, Rosa B; Sveinbjornsson, Gardar; Sulem, Patrick; Nielsen, Jonas B.; Jonsson, Stefan; Halldorsson, Gisli H; Melsted, Pall; Ivarsdottir, Erna V; Davidsson, Olafur B; Kristjansson, Ragnar P. (2018) Coding variants in RPL3L and MYZAP increase risk of atrial fibrillation. Communications Biology
  Academic article
• Turcot, Valérie; Lu, Yingchang; Highland, Heather M.; Schurmann, Claudia; Justice, Anne E.; Fine, Rebecca S.; Bradfield, Jonathan P.; Esko, Tonu; Giri, Ayush; Graff, Mariaelisa. (2018) Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. Nature Genetics
  Academic article
• Gusarova, Viktoria; O'Dushlaine, Colm; Teslovich, Tanya M.; Benotti, Peter N.; Mirshahi, Tooraj; Gottesman, Omri; Hout, Cristopher V. van; Murray, Michael F.; Mahajan, Anubha; Nielsen, Jonas B.. (2018) Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes. Nature Communications
  Academic article

2017

• Webb, Thomas R.; Erdmann, Jeanette; Stirrups, Kathleen E.; Stitziel, Nathan O.; Masca, Nicholas G.D.; Jansen, Henning; Kanoni, Stavroula; Nelson, Christopher P.; Ferrario, Paola G.; König, Inke R.. (2017) Systematic evaluation of pleiotropy identifies 6 further loci associated with coronary artery disease. Journal of the American College of Cardiology
  Academic article
• Justice, Anne E.; Winkler, Thomas W.; Feitosa, Mary F.; Graff, Misa; Fisher, Virginia A.; Young, Kristin; Barata, Llilda; Deng, Xuan; Czajkowski, Jacek; Hadley, David. (2017) Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Nature Communications
  Academic article
• Ferreira, Manuel A.; Vonk, Judith M; Baurecht, Hansjörg; Marenholz, Ingo; Tian, Chao; Hoffman, Joshua D; Helmer, Quinta; Tillander, Annika; Ullemar, Vilhelmina; Dongen, Jenny Van. (2017) Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology. Nature Genetics
  Academic article
• Liu, Dajiang J.; Peloso, Gina M.; Yu, Haojie; Butterworth, Adam S.; Wang, Xiao; Mahajan, Anubha; Saleheen, Danish; Emdin, Connor; Alam, Dewan; Alves, Alexessander Couto. (2017) Exome-wide association study of plasma lipids in >300,000 individuals. Nature Genetics
  Academic article
• Graff, Mariaelisa; Scott, Robert A.; Justice, Anne E.; Young, Kristin L.; Feitosa, Mary F.; Barata, Llilda; Winkler, Thomas W.; Chu, Audrey Y.; Mahajan, Anubha; Hadley, David. (2017) Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. PLoS Genetics
  Academic article
• Zhou, Wei; Fritsche, Lars; Das, Sayantan; Zhang, He; Nielsen, Jonas B.; Holmen, Oddgeir Lingaas; Chen, Jin; Lin, Maoxuan; Gabrielsen, Maiken Elvestad; Hveem, Kristian. (2017) Improving power of association tests using multiple sets of imputed genotypes from distributed reference panels. Genetic Epidemiology
  Academic article

2016

• Stitziel, Nathan O.; Stirrups, Kathleen E.; Masca, Nicholas G.D.; Erdmann, Jeanette; Ferrario, Paola G.; König, Inke R.; Weeke, Peter E.; Webb, Thomas R.; Auer, Paul L.; Schick, Ursula M.. (2016) Coding variation in ANGPTL4, LPL, and SVEP1 and the risk of coronary disease. New England Journal of Medicine
  Academic article
• Surendran, Praveen; Drenos, Fotios; Young, Robin; Warren, Helen; Cook, James P.; Manning, Alisa K.; Grarup, Niels; Sim, Xueling; Barnes, Daniel R.; Witkowska, Kate. (2016) Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension. Nature Genetics
  Academic article
• Lyngbakken, Magnus Nakrem; Røsjø, Helge; Holmen, Oddgeir; Nygård, Ståle; Dalen, Håvard; Hveem, Kristian; Omland, Torbjørn. (2016) Gender, High-Sensitivity Troponin I, and the Risk of Cardiovascular Events (from the Nord-Trøndelag Health Study). American Journal of Cardiology
  Academic article
• Ried, Janina S.; Jeff, Janina M.; Chu, Audrey Y.; Bragg-Gresham, Jennifer L.; Dongen, Jenny Van; Huffman, Jennifer E.; Ahluwalia, Tarunveer S.; Cadby, Gemma; Eklund, Niina; Eriksson, Joel. (2016) A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape. Nature Communications
  Academic article
• Ehret, Georg B.; Ferreira, Teresa; Chasman, Daniel I.; Jackson, Anne U.; Schmidt, Ellen M.; Johnson, Toby; Thorleifsson, Gudmar; Luan, Jian'An; Donnelly, Louise A.; Kanoni, Stavroula. (2016) The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nature Genetics
  Academic article
• Holmen, Jostein; Holmen, Turid Lingaas; Tverdal, Aage; Holmen, Oddgeir; Sund, Erik Reidar; Midthjell, Kristian. (2016) Blood pressure changes during 22-year of follow-up in large general population - the HUNT Study, Norway. BMC Cardiovascular Disorders
  Academic article
• Løset, Mari; Modalsli, Ellen Heilmann; Snekvik, Ingrid; Zhou, Wei; Chu, Yunhan; Gabrielsen, Maiken Elvestad; Holmen, Oddgeir Lingaas; Romundstad, Pål Richard; Abecasis, Goncalo; Willer, Cristen. (2016) HUNTing for Genes that Affect Psoriasis in ~2,900 Cases and ~48,000 Controls. Forum for Nordic Dermato-Venereology
  Conference abstract
• Zayats, Tetyana; Jacobsen, Kaya Kvarme; Kleppe, Rune; Jacob, CP; Kittel-Schneider, Sarah; Ribases, Marta; Ramos-Quiroga, JA; Richarte, Vanesa; Casas, M; Mota, NR. (2016) Exome chip analyses in adult attention deficit hyperactivity disorder. Translational Psychiatry
  Academic article

2015

• Shungin, Dmitry; Winkler, Thomas W.; Croteau-Chonka, Damien C.; Ferreira, Teresa; Locke, Adam E.; Mägi, Reedik; Strawbridge, Rona J.; Pers, Tune H.; Fischer, Krista; Justice, Anne E.. (2015) New genetic loci link adipose and insulin biology to body fat distribution. Nature
  Academic article
• Gaulton, Kyle J.; Ferreira, Teresa; Lee, Yeji; Raimondo, Anne; Mägi, Reedik; Reschen, Michael E.; Mahajan, Anubha; Locke, Adam; Rayner, N. William; Robertson, Neil. (2015) Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci. Nature Genetics
  Academic article
• Feng, Shuang; Pistis, Giorgio; Zhang, He; Zawistowski, Matthew; Mulas, Antonella; Zoledziewska, Magdalena; Holmen, Oddgeir; Busonero, Fabio; Sanna, Serena; Hveem, Kristian. (2015) Methods for association analysis and meta-analysis of rare variants in families. Genetic Epidemiology
  Academic article
• Tang, Clara S.; Zhang, He; Cheung, Chloe Y.Y.; Xu, Ming; Ho, Jenny C.Y.; Zhou, Wei; Cherny, Stacey S.; Zhang, Yan; Holmen, Oddgeir; Au, Ka-Wing. (2015) Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese. Nature Communications
  Academic article
• Locke, Adam E.; Kahali, Bratati; Berndt, Sonja I.; Justice, Anne E.; Pers, Tune H.; Day, Felix R.; Powell, Corey; Vedantam, Sailaja; Buchkovich, Martin L.; Yang, Jian. (2015) Genetic studies of body mass index yield new insights for obesity biology. Nature
  Academic article
• Omland, Torbjørn; Lemos, James A De; Holmen, Oddgeir; Dalen, Håvard; Benth, Jurate Saltyte; Nygård, Ståle; Hveem, Kristian; Røsjø, Helge. (2015) Impact of sex on the prognostic value of high-sensitivity cardiac troponin I in the general population: The HUNT study. Clinical Chemistry
  Academic article

2014

• Wood, Andrew R.; Esko, Tonu; Yang, Jian; Vedantam, Sailaja; Pers, Tune H; Gustafsson, Stefan; Chu, Audrey Y; Estrada, Karol; Luan, Jian'An; Kutalik, Zoltan. (2014) Defining the role of common variation in the genomic and biological architecture of adult human height. Nature Genetics
  Academic article
• Liu, Dajiang J.; Peloso, Gina M.; Zhan, Xiaowei; Holmen, Oddgeir; Zawistowski, Matthew; Feng, Shuang; Nikpay, Majid; Auer, Paul L.; Goel, Anuj; Zhang, He. (2014) Meta-analysis of gene-level tests for rare variant association. Nature Genetics
  Academic article
• Holmen, Oddgeir; Zhang, He; Zhou, Wei; Schmidt, Ellen; Hovelson, Daniel H; Langhammer, Arnulf; Løchen, Maja-Lisa; Ganesh, Santhi K; Mathiesen, Ellisiv B.; Vatten, Lars Johan. (2014) No large-effect low-frequency coding variation found for myocardial infarction. Human Molecular Genetics
  Academic article
• Kvehaugen, Anne Stine; Melien, Øyvind; Holmen, Oddgeir; Laivuori, Hannele; Dechend, Ralf; Staff, Anne Cathrine. (2014) Hypertension after preeclampsia and relation to the C1114G polymorphism (rs4606) in RGS2: Data from the Norwegian HUNT2 study. BMC Medical Genetics
  Academic article
• Mahajan, Anubha; Go, Min Jin; Zhang, Weihua; Below, Jennifer E; Gaulton, Kyle J; Ferreira, Teresa; Horikoshi, Momoko; Johnson, Andrew D; Ng, Maggie CY; Prokopenko, Inga. (2014) Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nature Genetics
  Academic article
• Crosby, Jacy; Peloso, Gina M; Auer, Paul L; Crosslin, David R; Stitziel, Nathan O; Lange, Leslie A; Lu, Yingchang; Tang, Zheng-Zheng; Zhang, He; Hindy, George. (2014) Loss-of-function mutations in APOC3, triglycerides, and coronary disease. New England Journal of Medicine
  Academic article
• Lange, LA; Hu, Y; Zhang, H; Xue, C; Schmidt, EM; Tang, ZZ; Bizon, C; Lange, EM; Smith, JD; Turner, EH. (2014) Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol. American Journal of Human Genetics
  Academic article
• Holmen, Oddgeir; Zhang, He; Fan, Yanbo; Hovelson, Daniel H; Schmidt, EM; Zhou, Wei; Guo, Yanhong; Zhang, Ji; Langhammer, Arnulf; Løchen, Maja-Lisa. (2014) Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk. Nature Genetics
  Academic article

2013

• Wu, Y; Waite, LL; Jackson, Anne U.; Sheu, WHH; Buyske, Steven; Absher, D; Arnett, DK; Boerwinkle, E; Bonnycastle, LL; Carty, CL. (2013) Trans-Ethnic Fine-Mapping of Lipid Loci Identifies Population-Specific Signals and Allelic Heterogeneity That Increases the Trait Variance Explained. PLoS Genetics
  Academic article
• Kvehaugen, Anne Stine; Melien, Øyvind; Holmen, Oddgeir; Laivuori, Hannele; Øian, Pål; Andersgaard, Alice Beathe; Dechend, Ralf; Staff, Anne Cathrine. (2013) Single Nucleotide Polymorphisms in G Protein Signaling Pathway Genes in Preeclampsia. Hypertension
  Academic article

2012

• Morris, AP; Voight, BF; Teslovich, TM; Ferreira, T; Segre, AV; Steinthorsdottir, V; Strawbridge, RJ; Khan, H; Grallert, H; Mahajan, A. (2012) Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nature Genetics
  Academic article

2011

• Chan, Y; Holmen, Oddgeir; Dauber, A; Vatten, Lars Johan; Havulinna, AS; Skorpen, Frank; Kvaløy, Kirsti; Silander, K; Nguyen, Thutrang T; Willer, C. (2011) Common variants show predicted polygenic effects on height in the tails of the distribution, except in extremely short individuals. PLoS Genetics
  Academic article

2010

• Holmen, Oddgeir; Romundstad, Solfrid; Melien, Øyvind. (2010) Association Between the G Protein beta 3 Subunit C825T Polymorphism and the Occurrence of Cardiovascular Disease in Hypertensives: The Nord-Trondelag Health Study (HUNT). American Journal of Hypertension
  Academic article