I am working as Adjunct Assoc. Prof. / researcher at the Department of Biotechnology, NTNU. My main research focus areas are bacterial transcriptional and translational regulation, biological tools development, and synthetic biology. Model organisms that I work with are: Escherichia coli, Pseudomonas putida KT2440, psychrophilic Pseudomonas, Psychrobacter spp. and Synechococcus sp. PCC 7002.
EU - H2020 - Advanced toolbox for rapid and cost-effective functional metagenomic screening - microbiology meets microfluidics. Involved as PI
PhotoSynLab - We practice open science
For curious minds, more information can be found on our lab website on what do we do: www.photosynlab.org
More information will follow!
TBT4165 - System Biology and Biological Networks
TBT4505 - Biotechnology - Specialization Course - Bioinformatics
Beal J, Haddock-Angelli T, Gershater M, de Mora K, Lizarazo M, Hollenhorst J, et al. Reproducibility of fluorescent expression from engineered biological constructs in E. coli. PLoS ONE.
Arnfinnsdottir, NB., Bjørkøy, A., Lale, R., Sletmoen, M. Heterogeneity in GFP expression in isogenic populations of P. putida KT2440 investigated using flow cytometry and bacterial microarrays. RSC Advances
Moghadam MM, Albersmeier A,Winkler A, Cimmino L, Rise K, Hohmann-Marriott FM, Kalinowski J, Rückert C, Wentzel A, Lale, R. Isolation and genome sequencing of four Arctic marine Psychrobacter strains exhibiting multicopper oxidase activity. BMC Genomics.
Petrov, V., Balasubramaniam, S., Lale, R.
, Moltchanov, D., Lio’, P., Koucheryavy, Y. Forward and Reverse Coding for Chromosome Transfer in Bacterial Nanonetworks.
Nano Communication Networks.
Røkke, G., Korvald, E., Pahr, J., Øyås, O., and Lale, R. BioBrick assembly standards and techniques and associated software tools.
DNA Cloning and Assembly Methods. Methods in Molecular Biology, editors by Lale, R.
and Valla, S. Volume 1116, 2014, pp 1-24
Springer Protocols, Humana Press.
Balzer, S., Kucharova, V., Megerle, J., Lale, R.
, Brautaset, T., Valla, S. A comparative analysis of the properties of regulated promoter systems commonly used for recombinant gene expression in Escherichia coli.
Microbial Cell Factories, 12:26.
, Berg, L., Stüttgen, F., Netzer, R., Stafsnes, M., Brautaset, T., Aune, T.E.V. and Valla. S. Continuous control of the flow in biochemical pathways through 5'-UTR sequence modifications in mRNA expressed from the broad-host-range Pm promoter.
Appl. Env. Mircobiol. 77: 2648-2655.
Aune, T. E. V., Bakke, I., Drabløs, F., Lale, R.
, Brautaset, T. and Valla, S. Directed evolution of the transcription factor XylS for development of improved expression systems.
Microb. Biotechnol. 3:1, 38–47.
Bar, N. S. and Lale, R. Modeling and control of the protein synthesis process in eukaryotic cells. 47th IEEE Proceedings: Conference on Decision and Control (CDC) 179-184.
Lale, R., Tukel, C. and Akcelik, M. Protein profile and plasmid content of Lactococcus lactis subsp lactis LL5Z and Lactococcus lactis subsp cremoris LC79 strains under several stress conditions. T. J. Vet. An. Sci. 31(4), 247-252.