Ben Michael Brumpton
Ben Michael Brumpton
Associate Professor Genetic Epidemiology
Department of Public Health and NursingBackground and activities
My research concerns the use of genetic data and phenotypic information collected from population-based health surveys and electronic health records within epidemiological frameworks to make causal inference. My methodologies include Mendelian randomization and genetic epidemiology.
Major research projects:
Scientific, academic and artistic work
Displaying a selection of activities. See all publications in the database
Journal publications
- (2022) Taller height and risk of coronary heart disease and cancer: A within-sibship Mendelian randomization study. eLIFE. vol. 11.
- (2021) Bone mineral density and risk of cardiovascular disease in men and women: the HUNT study. European Journal of Epidemiology (EJE).
- (2021) Genome-wide association study of cardiac troponin i in the general population. Human Molecular Genetics. vol. 30 (21).
- (2020) Spirometric Classifications of COPD Severity as Predictive Markers for Clinical Outcomes: The HUNT Study. American Journal of Respiratory and Critical Care Medicine. vol. 203 (8).
- (2020) Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses. Nature Communications. vol. 11.
- (2020) Mendelian randomization study of maternal influences on birthweight and future cardiometabolic risk in the HUNT cohort. Nature Communications. vol. 11:5404.
- (2020) Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease. Nature Communications.
- (2020) MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk. Nature Communications. vol. 11:4093.
- (2020) GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer. Nature Communications. vol. 11:3981.
- (2019) Variation in serum PCSK9 (proprotein convertase subtilisin/kexin type 9), cardiovascular disease risk, and an investigation of potential unanticipated effects of PCSK9 inhibition. Circulation: Genomic and precision medicine. vol. 12 (1).
- (2019) Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study. Nature Methods. vol. 16:e1002739 (1).
- (2019) Investigating causal relations between sleep traits and risk of breast cancer in women: Mendelian randomisation study. The BMJ. vol. 365:l2327.
- (2019) Adiposity and asthma in adults: a bidirectional Mendelian randomisation analysis of The HUNT Study. Thorax.
- (2018) Associations of asthma and asthma control with atrial fibrillation risk: Results from the Nord-Trøndelag health study (HUNT). JAMA cardiology. vol. 3 (8).
- (2018) Serum 25-hydroxyvitamin D levels and risk of lung cancer and histologic types: a Mendelian randomization analysis of the HUNT study. European Respiratory Journal. vol. 51 (6).
- (2017) Prospective study of insomnia and incident asthma in adults: The HUNT study. European Respiratory Journal. vol. 49 (2).
- (2017) Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology. Nature Genetics. vol. 49 (12).
Report/dissertation
- (2014) Risk factors for the development of asthma in adults: adiposity, metabolic syndrome, mental distress and their interplay. 2014.