Helga Ertesvåg
+4773598678
Kjemi 3, 3-328, Gløshaugen, Sem Sælandsvg 6
About
I am a research professor and adjunct professor at the Department of Biotechnology and Food Science and Nobipol. My research has been focused on microbiology/biochemistry/biotechnology on industrial microorganisms, both basic and applied projects. I teach parts of Biochemistry II and the PhD course BT8120.
Areas of speciality
- Understand and control the biosynthesis of alginate in Pseudomonas fluorescens and Azotobacter vinelandii
- Studies of alginate-modifying enzymes
- Design enzymes with new properties.
- Develop microorganisms (bacteria and thraustochytrids) producing feed ingredients, especially DHA and EPA
- Study the effect of bacterially produced surfactants, proteins and polysaccharides on the floatability of nanosized mineral particles.
- A. vinelandii encystment
- The collection of Actinomycetes from the Trondheim fjord
- Tutoring master and PhD students
Background and expertise
I took my master degree in 1987, and PhD in 1994, both at the University of Trondheim, AVH. From 1987 to 2004 I was employed at SINTEF as a researcher/senior researcher. From 2005 I have been working at NTNU.
My work has been within industrial biotechnology. In most cases the motivation has been to understand the bacteria and the properties of pathways and enzymes in order to ultimately construct bacteria that may produce various products (proteins or metabolites) at levels sufficient for an industrial process. I now have expertise on cloning, homologous recombination and tailoring of genetic tools in different bacteria. Another aspect has been production, purification and characterization of enzymes. The projects have also involved genome mining and the use of other databases to find genes coding for a desired activity or to better understand metabolic pathways.
Research
My research has been focused on microbiology/biochemistry/biotechnology on industrial microorganisms, both basic and applied projects. My work has been within industrial biotechnology. In most cases the motivation has been to understand the bacteria and the properties of pathways and enzymes in order to ultimately construct bacteria that may produce various products (proteins or metabolites) at levels sufficent for an industrial process. I have now expertise on cloning, homologous recombination and tailoring of genetic tools in different bacteria. Another aspect has been production, purification and characterization of enzymes. the projects have also involved genome mining and the use of other databases to find genes coding for a desired activity or to better understand metbolic pathways.
- Understand and control the biosynthesis of alginate in Pseudomonas fluorescens and Azotobacter vinelandii
- Studies of alginate-modifying enzymes
- Design enzymes with new properties.
- Develop microorganisms (bacteria and thraustochytrids) producing feed ingredients, especially DHA and EPA
- Study the effect of bacterially produced surfactants, proteins and polysaccharides on the floatability of nanosized mineral particles.
- A. vinelandii encystment
- The collection of Actinomycetes from the Trondheim fjord
Publications
2024
-
Ertesvåg, Helga.
(2024)
Natrium-kalium-pumpa.
Store Norske Leksikon (Nettutgaven)
Popular science article
2023
-
Slabov, Vladislav;
Jain, Garima;
Chernyshova, Irina;
Kota, Hanumantha Rao;
Ertesvåg, Helga.
(2023)
Alginates as Green Flocculants for Metal Oxide Nanoparticles.
Transactions of the Indian Institute of Metals
Academic article
-
Rau, E-Ming;
Aasen, Inga Marie;
Bartosova, Zdenka;
Bruheim, Per;
Ertesvåg, Helga.
(2023)
Utilizing lipidomics and fatty acid synthase inhibitors to explore lipid accumulation in two thraustochytrid species.
Algal Research
Academic article
-
Petersen, Agnes Beenfeldt;
Tøndervik, Anne;
Gaardløs, Margrethe;
Ertesvåg, Helga;
Sletta, Håvard;
Aachmann, Finn Lillelund.
(2023)
Mannuronate C-5 epimerases and their use in alginate modification.
Essays in Biochemistry
Academic literature review
2022
-
Rau, E-Ming;
Bartosova, Zdenka;
Kristiansen, Kåre Andre;
Aasen, Inga Marie;
Bruheim, Per;
Ertesvåg, Helga.
(2022)
Overexpression of two new acyl-CoA:diacylglycerol acyltransferase 2-like acyl-CoA:sterol acyltransferases enhanced squalene accumulation in Aurantiochytrium limacinum.
Frontiers in Microbiology
Academic article
-
Jain, Garima;
Ertesvåg, Helga.
(2022)
Improved site-specific mutagenesis in Rhodococcus opacus using a novel conditional suicide plasmid.
Applied Microbiology and Biotechnology
Professional article
-
Tøndervik, Anne;
Aune, Randi;
Degelmann, Adelheid;
Piontek, Michael;
Ertesvåg, Helga;
Skjåk-Bræk, Gudmund;
Sletta, Håvard.
(2022)
Strain Construction and Process Development for Efficient Recombinant Production of Mannuronan C-5 Epimerases in Hansenula polymorpha.
Frontiers in Plant Science
Academic article
2021
-
Gaardløs, Margrethe;
Heggeset, Tonje Marita Bjerkan;
Tøndervik, Anne;
Teze, David;
Svensson, Birte;
Ertesvåg, Helga;
Sletta, Håvard;
Aachmann, Finn Lillelund.
(2021)
Mechanistic Basis for Understanding the Dual Activities of the
Bifunctional Azotobacter vinelandii Mannuronan C-5-Epimerase
and Alginate Lyase AlgE7.
Applied and Environmental Microbiology
Academic article
-
Rau, E-Ming;
Aasen, Inga Marie;
Ertesvåg, Helga.
(2021)
A non-canonical Δ9-desaturase synthesizing palmitoleic acid identified in the thraustochytrid Aurantiochytrium sp. T66.
Applied Microbiology and Biotechnology
Academic article
-
Rau, E-Ming;
Ertesvåg, Helga.
(2021)
Method Development Progress in Genetic Engineering of Thraustochytrids.
Marine Drugs
Academic literature review
-
Bartosova, Zdenka;
Ertesvåg, Helga;
Nyfløt, Eirin Lishaugen;
Kämpe, Kristoffer;
Aasen, Inga Marie;
Bruheim, Per.
(2021)
Combined Metabolome and Lipidome analyses for in-depth characterization of lipid accumulation in the DHA producing Aurantiochytrium sp. T66.
Metabolites
Academic article
2020
-
Mærk, Mali;
Jakobsen, Øyvind Mejdell;
Sletta, Håvard;
Klinkenberg, Geir;
Tøndervik, Anne;
Ellingsen, Trond Erling;
Valla, Svein;
Ertesvåg, Helga.
(2020)
Identification of Regulatory Genes and Metabolic Processes Important for Alginate Biosynthesis in Azotobacter vinelandii by Screening of a Transposon Insertion Mutant Library.
Frontiers in Bioengineering and Biotechnology
Academic article
-
Jain, Garima;
Havskjold, Håkon;
Dhar, Priyanka;
Ertesvåg, Helga;
Chernyshova, Irina;
Kota, Hanumantha Rao.
(2020)
Green foam-based methods of mineral and ion separation.
Academic chapter
-
Gawin, Agnieszka Maria;
Tietze, Lisa;
Aarstad, Olav Andreas;
Aachmann, Finn Lillelund;
Brautaset, Trygve;
Ertesvåg, Helga.
(2020)
Functional characterization of three Azotobacter chroococcum alginate-modifying enzymes related to the Azotobacter vinelandii AlgE mannuronan C-5-epimerase family.
Scientific Reports
Academic article
2019
-
Vilnes, Marte;
Ertesvåg, Helga.
(2019)
Genetisk modifisering av lipidmetabolismen i Rhodococcus opacus PD630.
NTNU
Master thesis
-
Heggeset, Tonje Marita Bjerkan;
Ertesvåg, Helga;
Liu, Bin;
Ellingsen, Trond Erling;
Vadstein, Olav;
Aasen, Inga Marie.
(2019)
Lipid and DHA-production in Aurantiochytrium sp. – Responses to nitrogen starvation and oxygen limitation revealed by analyses of production kinetics and global transcriptomes.
Scientific Reports
Academic article
2018
-
Moreno, Soledad;
Ertesvåg, Helga;
Valla, Svein;
Nunez, Cinthia;
Espín, Guadalupe;
Cocotl-Yanez, Miguel.
(2018)
RpoS controls the expression and the transport of the AlgE1-7 epimerases in Azotobacter vinelandii.
FEMS Microbiology Letters
Academic article
2017
-
Maleki, Susan;
Mærk, Mali;
Hrudikova, Radka;
Valla, Svein;
Ertesvåg, Helga.
(2017)
New insights into Pseudomonas fluorescens alginate biosynthesis relevant for the establishment of an efficient production process for microbial alginates.
New Biotechnology
Academic literature review
-
Maleki, Susan;
Hrudikova, Radka;
Zotchev, Sergey;
Ertesvåg, Helga.
(2017)
Identification of a new phosphatase enzyme potentially involved in the sugar phosphate stress response in Pseudomonas fluorescens.
Applied and Environmental Microbiology
Academic article
-
Ertesvåg, Helga;
Sletta, Håvard;
Senneset, Mona;
Sun, Yi-Qian;
Klinkenberg, Geir;
Konradsen, Therese Aursand;
Ellingsen, Trond Erling;
Valla, Svein.
(2017)
Identification of genes affecting alginate biosynthesis in Pseudomonas fluorescens by screening a transposon insertion library.
BMC Genomics
Academic article
2016
-
Moral, Cigdem Kivilcimdan;
Ertesvåg, Helga;
Sanin, F. Dilek.
(2016)
Guluronic acid content as a factor affecting turbidity removal potential of alginate.
Environmental Science and Pollution Research
Academic article
-
Maleki, Susan;
Almaas, Eivind;
Zotchev, Sergey;
Valla, Svein;
Ertesvåg, Helga.
(2016)
Alginate Biosynthesis Factories in Pseudomonas fluorescens
: Localization and Correlation with Alginate Production Level.
Applied and Environmental Microbiology
Academic article
-
Aasen, Inga Marie;
Ertesvåg, Helga;
Heggeset, Tonje Marita Bjerkan;
Liu, Bin;
Brautaset, Trygve;
Vadstein, Olav;
Ellingsen, Trond Erling.
(2016)
Thraustochytrids as production organisms for docosahexaenoic acid (DHA), squalene, and carotenoids.
Applied Microbiology and Biotechnology
Academic literature review
2015
-
Maleki, Susan;
Mærk, Mali;
Valla, Svein;
Ertesvåg, Helga.
(2015)
Mutational analyses of glucose dehydrogenase and glucose-6-phosphate dehydrogenase genes in Pseudomonas fluorescens reveal their effects on growth and alginate production.
Applied and Environmental Microbiology
Academic article
-
Ertesvåg, Helga.
(2015)
Alginate-modifying enzymes: Biological roles and biotechnological uses.
Frontiers in Microbiology
Academic literature review
2014
-
Mærk, Mali;
Johansen, Jostein;
Ertesvåg, Helga;
Drabløs, Finn;
Valla, Svein.
(2014)
Safety in numbers: multiple occurrences of highly similar homologs among Azotobacter vinelandii carbohydrate metabolism proteins probably confer adaptive benefits.
BMC Genomics
Academic article
2010
-
Tøndervik, Anne;
Klinkenberg, Geir;
Aarstad, Olav Andreas;
Drabløs, Finn;
Ertesvåg, Helga;
Ellingsen, Trond Erling;
Skjåk-Bræk, Gudmund;
Valla, Svein;
Sletta, Håvard.
(2010)
Isolation of Mutant Alginate Lyases with Cleavage Specificity for Di-guluronic Acid Linkages.
Journal of Biological Chemistry
Academic article
2009
-
Setubal, Joao C.;
Santos, Patricia dos;
Goldman, Barry S.;
Ertesvåg, Helga;
Espín, Guadalupe;
Rubio, Luis M.;
Valla, Svein;
Almeida, Nalvo F.;
Balasubramanian, Divya;
Cromes, Lindsey.
(2009)
Genome sequence of Azotobacter vinelandii, an obligate aerobe specialized to support diverse anaerobic metabolic processes.
Journal of Bacteriology
Academic article
-
Gimmestad, Martin;
Ertesvåg, Helga;
Heggeset, Tonje Marita;
Aarstad, Olav Andreas;
Svanem, Britt Iren Glærum;
Valla, Svein.
(2009)
Characterization of Three New Azotobacter vinelandii Alginate Lyases, One of Which Is Involved in Cyst Germination.
Journal of Bacteriology
Academic article
2006
-
Gimmestad, Martin;
Steigedal, Magnus;
Ertesvåg, Helga;
Moreno, Soledad;
Christensen, Bjørn Erik;
Espín, Guadalupe;
Valla, Svein.
(2006)
Identification and characterization of an Azotobacter vinelandii type I secretion system responsible for export of the AlgE-Type mannuronan C-5-epimerases.
Journal of Bacteriology
Academic article
-
Mærk, Mali;
Valla, Svein;
Ertesvåg, Helga.
(2006)
Bioinformatisk analyse og genetisk modifisering av karbohydratmetabolismen i Pseudomonas fluorescens, med fokus på alginatsyntese fra glukose.
Norges teknisk-naturvitenskapelige universitet
Master thesis
2005
-
Bakkevig, Karianne;
Sletta, Håvard;
Gimmestad, Martin;
Aune, Randi;
Ertesvåg, Helga;
Degnes, Kristin;
Christensen, Bjørn Erik;
Ellingsen, Trond Erling;
Valla, Svein.
(2005)
Role of the Pseudomonas fluorescens alginate lyase (AlgL) in clearing the periplasm of alginates not exported to the extracellular environment.
Journal of Bacteriology
Academic article
2004
-
Bjerkan, Tonje Marita;
Bender, Carol;
Ertesvåg, Helga;
Drabløs, Finn;
Fakhr, Mohamed K.;
Preston, Lori A.;
Skjåk-Bræk, Gudmund;
Valla, Svein.
(2004)
The pseudomonas syringae genome encodes a combined mannuronan C-5-epimerase and O-acetylhydrolase, which strongly enhances the predicted gel-forming properties of alginates.
Journal of Biological Chemistry
Academic article
2003
-
Gimmestad, Martin;
Sletta, Håvard;
Ertesvåg, Helga;
Bakkevig, Karianne;
Jain, Sumita;
Suh, Sang-jin;
Skjåk-Bræk, Gudmund;
Ellingsen, Trond E.;
Ohman, Dennis E.;
Valla, Svein.
(2003)
The Pseudomonas fluorescens AlgG protein, but not its mannuronan C-5-epimerase activity, is needed fro alginate polymer formation.
Journal of Bacteriology
Academic article
Journal publications
-
Maleki, Susan;
Mærk, Mali;
Hrudikova, Radka;
Valla, Svein;
Ertesvåg, Helga.
(2017)
New insights into Pseudomonas fluorescens alginate biosynthesis relevant for the establishment of an efficient production process for microbial alginates.
New Biotechnology
Academic literature review
-
Rau, E-Ming;
Bartosova, Zdenka;
Kristiansen, Kåre Andre;
Aasen, Inga Marie;
Bruheim, Per;
Ertesvåg, Helga.
(2022)
Overexpression of two new acyl-CoA:diacylglycerol acyltransferase 2-like acyl-CoA:sterol acyltransferases enhanced squalene accumulation in Aurantiochytrium limacinum.
Frontiers in Microbiology
Academic article
-
Slabov, Vladislav;
Jain, Garima;
Chernyshova, Irina;
Kota, Hanumantha Rao;
Ertesvåg, Helga.
(2023)
Alginates as Green Flocculants for Metal Oxide Nanoparticles.
Transactions of the Indian Institute of Metals
Academic article
-
Maleki, Susan;
Mærk, Mali;
Valla, Svein;
Ertesvåg, Helga.
(2015)
Mutational analyses of glucose dehydrogenase and glucose-6-phosphate dehydrogenase genes in Pseudomonas fluorescens reveal their effects on growth and alginate production.
Applied and Environmental Microbiology
Academic article
-
Mærk, Mali;
Jakobsen, Øyvind Mejdell;
Sletta, Håvard;
Klinkenberg, Geir;
Tøndervik, Anne;
Ellingsen, Trond Erling;
Valla, Svein;
Ertesvåg, Helga.
(2020)
Identification of Regulatory Genes and Metabolic Processes Important for Alginate Biosynthesis in Azotobacter vinelandii by Screening of a Transposon Insertion Mutant Library.
Frontiers in Bioengineering and Biotechnology
Academic article
-
Gimmestad, Martin;
Steigedal, Magnus;
Ertesvåg, Helga;
Moreno, Soledad;
Christensen, Bjørn Erik;
Espín, Guadalupe;
Valla, Svein.
(2006)
Identification and characterization of an Azotobacter vinelandii type I secretion system responsible for export of the AlgE-Type mannuronan C-5-epimerases.
Journal of Bacteriology
Academic article
-
Gaardløs, Margrethe;
Heggeset, Tonje Marita Bjerkan;
Tøndervik, Anne;
Teze, David;
Svensson, Birte;
Ertesvåg, Helga;
Sletta, Håvard;
Aachmann, Finn Lillelund.
(2021)
Mechanistic Basis for Understanding the Dual Activities of the
Bifunctional Azotobacter vinelandii Mannuronan C-5-Epimerase
and Alginate Lyase AlgE7.
Applied and Environmental Microbiology
Academic article
-
Maleki, Susan;
Hrudikova, Radka;
Zotchev, Sergey;
Ertesvåg, Helga.
(2017)
Identification of a new phosphatase enzyme potentially involved in the sugar phosphate stress response in Pseudomonas fluorescens.
Applied and Environmental Microbiology
Academic article
-
Ertesvåg, Helga.
(2015)
Alginate-modifying enzymes: Biological roles and biotechnological uses.
Frontiers in Microbiology
Academic literature review
-
Ertesvåg, Helga;
Sletta, Håvard;
Senneset, Mona;
Sun, Yi-Qian;
Klinkenberg, Geir;
Konradsen, Therese Aursand;
Ellingsen, Trond Erling;
Valla, Svein.
(2017)
Identification of genes affecting alginate biosynthesis in Pseudomonas fluorescens by screening a transposon insertion library.
BMC Genomics
Academic article
-
Bjerkan, Tonje Marita;
Bender, Carol;
Ertesvåg, Helga;
Drabløs, Finn;
Fakhr, Mohamed K.;
Preston, Lori A.;
Skjåk-Bræk, Gudmund;
Valla, Svein.
(2004)
The pseudomonas syringae genome encodes a combined mannuronan C-5-epimerase and O-acetylhydrolase, which strongly enhances the predicted gel-forming properties of alginates.
Journal of Biological Chemistry
Academic article
-
Ertesvåg, Helga.
(2024)
Natrium-kalium-pumpa.
Store Norske Leksikon (Nettutgaven)
Popular science article
-
Rau, E-Ming;
Aasen, Inga Marie;
Ertesvåg, Helga.
(2021)
A non-canonical Δ9-desaturase synthesizing palmitoleic acid identified in the thraustochytrid Aurantiochytrium sp. T66.
Applied Microbiology and Biotechnology
Academic article
-
Gawin, Agnieszka Maria;
Tietze, Lisa;
Aarstad, Olav Andreas;
Aachmann, Finn Lillelund;
Brautaset, Trygve;
Ertesvåg, Helga.
(2020)
Functional characterization of three Azotobacter chroococcum alginate-modifying enzymes related to the Azotobacter vinelandii AlgE mannuronan C-5-epimerase family.
Scientific Reports
Academic article
-
Moral, Cigdem Kivilcimdan;
Ertesvåg, Helga;
Sanin, F. Dilek.
(2016)
Guluronic acid content as a factor affecting turbidity removal potential of alginate.
Environmental Science and Pollution Research
Academic article
-
Setubal, Joao C.;
Santos, Patricia dos;
Goldman, Barry S.;
Ertesvåg, Helga;
Espín, Guadalupe;
Rubio, Luis M.;
Valla, Svein;
Almeida, Nalvo F.;
Balasubramanian, Divya;
Cromes, Lindsey.
(2009)
Genome sequence of Azotobacter vinelandii, an obligate aerobe specialized to support diverse anaerobic metabolic processes.
Journal of Bacteriology
Academic article
-
Maleki, Susan;
Almaas, Eivind;
Zotchev, Sergey;
Valla, Svein;
Ertesvåg, Helga.
(2016)
Alginate Biosynthesis Factories in Pseudomonas fluorescens
: Localization and Correlation with Alginate Production Level.
Applied and Environmental Microbiology
Academic article
-
Rau, E-Ming;
Ertesvåg, Helga.
(2021)
Method Development Progress in Genetic Engineering of Thraustochytrids.
Marine Drugs
Academic literature review
-
Heggeset, Tonje Marita Bjerkan;
Ertesvåg, Helga;
Liu, Bin;
Ellingsen, Trond Erling;
Vadstein, Olav;
Aasen, Inga Marie.
(2019)
Lipid and DHA-production in Aurantiochytrium sp. – Responses to nitrogen starvation and oxygen limitation revealed by analyses of production kinetics and global transcriptomes.
Scientific Reports
Academic article
-
Jain, Garima;
Ertesvåg, Helga.
(2022)
Improved site-specific mutagenesis in Rhodococcus opacus using a novel conditional suicide plasmid.
Applied Microbiology and Biotechnology
Professional article
-
Tøndervik, Anne;
Klinkenberg, Geir;
Aarstad, Olav Andreas;
Drabløs, Finn;
Ertesvåg, Helga;
Ellingsen, Trond Erling;
Skjåk-Bræk, Gudmund;
Valla, Svein;
Sletta, Håvard.
(2010)
Isolation of Mutant Alginate Lyases with Cleavage Specificity for Di-guluronic Acid Linkages.
Journal of Biological Chemistry
Academic article
-
Rau, E-Ming;
Aasen, Inga Marie;
Bartosova, Zdenka;
Bruheim, Per;
Ertesvåg, Helga.
(2023)
Utilizing lipidomics and fatty acid synthase inhibitors to explore lipid accumulation in two thraustochytrid species.
Algal Research
Academic article
-
Petersen, Agnes Beenfeldt;
Tøndervik, Anne;
Gaardløs, Margrethe;
Ertesvåg, Helga;
Sletta, Håvard;
Aachmann, Finn Lillelund.
(2023)
Mannuronate C-5 epimerases and their use in alginate modification.
Essays in Biochemistry
Academic literature review
-
Tøndervik, Anne;
Aune, Randi;
Degelmann, Adelheid;
Piontek, Michael;
Ertesvåg, Helga;
Skjåk-Bræk, Gudmund;
Sletta, Håvard.
(2022)
Strain Construction and Process Development for Efficient Recombinant Production of Mannuronan C-5 Epimerases in Hansenula polymorpha.
Frontiers in Plant Science
Academic article
-
Aasen, Inga Marie;
Ertesvåg, Helga;
Heggeset, Tonje Marita Bjerkan;
Liu, Bin;
Brautaset, Trygve;
Vadstein, Olav;
Ellingsen, Trond Erling.
(2016)
Thraustochytrids as production organisms for docosahexaenoic acid (DHA), squalene, and carotenoids.
Applied Microbiology and Biotechnology
Academic literature review
-
Bakkevig, Karianne;
Sletta, Håvard;
Gimmestad, Martin;
Aune, Randi;
Ertesvåg, Helga;
Degnes, Kristin;
Christensen, Bjørn Erik;
Ellingsen, Trond Erling;
Valla, Svein.
(2005)
Role of the Pseudomonas fluorescens alginate lyase (AlgL) in clearing the periplasm of alginates not exported to the extracellular environment.
Journal of Bacteriology
Academic article
-
Moreno, Soledad;
Ertesvåg, Helga;
Valla, Svein;
Nunez, Cinthia;
Espín, Guadalupe;
Cocotl-Yanez, Miguel.
(2018)
RpoS controls the expression and the transport of the AlgE1-7 epimerases in Azotobacter vinelandii.
FEMS Microbiology Letters
Academic article
-
Gimmestad, Martin;
Sletta, Håvard;
Ertesvåg, Helga;
Bakkevig, Karianne;
Jain, Sumita;
Suh, Sang-jin;
Skjåk-Bræk, Gudmund;
Ellingsen, Trond E.;
Ohman, Dennis E.;
Valla, Svein.
(2003)
The Pseudomonas fluorescens AlgG protein, but not its mannuronan C-5-epimerase activity, is needed fro alginate polymer formation.
Journal of Bacteriology
Academic article
-
Mærk, Mali;
Johansen, Jostein;
Ertesvåg, Helga;
Drabløs, Finn;
Valla, Svein.
(2014)
Safety in numbers: multiple occurrences of highly similar homologs among Azotobacter vinelandii carbohydrate metabolism proteins probably confer adaptive benefits.
BMC Genomics
Academic article
-
Bartosova, Zdenka;
Ertesvåg, Helga;
Nyfløt, Eirin Lishaugen;
Kämpe, Kristoffer;
Aasen, Inga Marie;
Bruheim, Per.
(2021)
Combined Metabolome and Lipidome analyses for in-depth characterization of lipid accumulation in the DHA producing Aurantiochytrium sp. T66.
Metabolites
Academic article
-
Gimmestad, Martin;
Ertesvåg, Helga;
Heggeset, Tonje Marita;
Aarstad, Olav Andreas;
Svanem, Britt Iren Glærum;
Valla, Svein.
(2009)
Characterization of Three New Azotobacter vinelandii Alginate Lyases, One of Which Is Involved in Cyst Germination.
Journal of Bacteriology
Academic article
Part of book/report
-
Jain, Garima;
Havskjold, Håkon;
Dhar, Priyanka;
Ertesvåg, Helga;
Chernyshova, Irina;
Kota, Hanumantha Rao.
(2020)
Green foam-based methods of mineral and ion separation.
Academic chapter
Student thesis or dissertation
-
Vilnes, Marte;
Ertesvåg, Helga.
(2019)
Genetisk modifisering av lipidmetabolismen i Rhodococcus opacus PD630.
NTNU
Master thesis
-
Mærk, Mali;
Valla, Svein;
Ertesvåg, Helga.
(2006)
Bioinformatisk analyse og genetisk modifisering av karbohydratmetabolismen i Pseudomonas fluorescens, med fokus på alginatsyntese fra glukose.
Norges teknisk-naturvitenskapelige universitet
Master thesis
Teaching
Courses
Outreach
2023
-
Conference lecture
2021
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Conference posterRau, E-Ming; Ertesvåg, Helga; Collier, Jackie L; Aasen, Inga Marie. (2021) A Novel Protein of the Thraustochytrid Aurantiochytrium sp. T66 Homologous to Δ12-desaturases Has Δ9- desaturase Activity and Synthesizes Palmitoleic Acid. world microbe forum 2021
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Conference posterJain, Garima; Ertesvåg, Helga. (2021) Construction and Use of a New Conditional Suicide Plasmid to Delete an Essential Gene for Mycolic Acid Biosynthesis in Rhodococcus opacus. WORLD MICROBE FORUM, ASM and FEMS collaboration
2020
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LectureRau, E-Ming; Ertesvåg, Helga. (2020) Project AUROMEGA: a fatty acid desaturase of Aurantiochytrium sp. T66. Digital Life 2020
2019
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Conference lectureAasen, Inga Marie; Haslene-Hox, Hanne; Ertesvåg, Helga; Heggeset, Tonje Marita Bjerkan; Bruheim, Per. (2019) Fatty acid synthesis in Aurantiochytrium sp, revealed by analyses of growth and production kinetics and global proteomes. First International Conference on Labyrinthulean Protists (ICoLP)
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Conference lectureHeggeset, Tonje Marita Bjerkan; Ertesvåg, Helga; Liu, Bin; Aasen, Inga Marie. (2019) Genome annotation and transcriptome analysis of the lipid- and DHA-accumulating Aurantiochytrium sp. T66. First International Conference on Labyrinthulean Protists (ICoLP)
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Conference posterErtesvåg, Helga; Haslene-Hox, Hanne; Aasen, Inga Marie; Almaas, Eivind; Bartosova, Zdenka; Heggeset, Tonje Marita Bjerkan; Le, Simone Balzer; Rau, E-Ming; Stafsnes, Marit Hallvardsdotter; Voigt, Andre. (2019) Industrial microbiology – 'omics methods and modelling as tools for process optimization. DigitalLife 2019
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Conference lectureAasen, Inga Marie; Bartosova, Zdenka; Haslene-Hox, Hanne; Heggeset, Tonje Marita Bjerkan; Stafsnes, Marit Hallvardsdotter; Bruheim, Per; Ertesvåg, Helga. (2019) Elucidating lipid accumulation and DHA synthesis in Aurantiochytrium sp. strain T66 using -omics technologies. NFM Meeting, Applied and Environmental Microbiology
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Conference posterHavskjold, Håkon; Jain, Garima; Dhar, Priyanka; Ertesvåg, Helga; Chernyshova, Irina; Kota, Hanumantha Rao. (2019) Toward sustainable recovery of Rare Earth Elements: Separation of CeO2 and Fe2O3 nanoparticles using biosurfactants. Norwegian NanoSymposium 2019
2018
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Conference lectureVadstein, Olav; Ertesvåg, Helga; Aasen, Inga Marie; Nymark, Marianne. (2018) Microbes as production organisms of DHA/EPA: The need for strain improvement. AQUA 2018
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Conference lectureErtesvåg, Helga; Heggeset, Tonje Marita Bjerkan; Liu, Bin; Aasen, Inga Marie. (2018) Lipid accumulation and DHA synthesis in Aurantiochytrium sp. T66, what is revealed by RNAseq?. Digital Life 2018
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Conference lectureAasen, Inga Marie; Ertesvåg, Helga; Heggeset, Tonje Marita Bjerkan; Vadstein, Olav; Sevgeli, Huseyin. (2018) Production of heterotrophic microorganisms for use as a source of long-chain omega3 fatty acids in aquafeed. Aqua 2018 – World Aquaculture Society Conference
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Conference lectureAasen, Inga Marie; Ertesvåg, Helga; Heggeset, Tonje Marita Bjerkan; Vadstein, Olav; Broli, Gunn; Sevgeli, Huseyin; Nanton, Dominic. (2018) Heterotrofe mikroorganismer som kilde for omega3-fettsyrer i fiskefôr. Havbruk 2018
2017
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LectureErtesvåg, Helga. (2017) Biosyntese av omega-3 feittsyrer i Thraustochytridar. BUG foredrag "Bærekraftig mat"
2015
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Conference lectureMaleki, Susan; Mærk, Mali; Hrudikova, Radka; Valla, Svein; Ertesvåg, Helga. (2015) In Pseudomonas fluorescens alginate production levels are determined by the available fructose 6-phosphate. 8th European Symposium on Biopolymers
2014
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LectureErtesvåg, Helga. (2014) Modifiserte mikroorganismer som nye kjelder til fóringrediensar. Havbruk – tilgang på fórråstoffer
2013
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Conference posterMoral, Çiğdem Kıvılcımdan; Ertesvåg, Helga; Sanin, F. Dilek. (2013) USE OF POST-EPIMERIZED ALGINATE IN WATER TREATMENT. Istanbul International Solid Waste, Water and Wastewater Congress
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Conference lectureTøndervik, Anne; Aachmann, Finn Lillelund; Svanem, Britt Iren Glærum; Klinkenberg, Geir; Ellingsen, Trond Erling; Aarstad, Olav Andreas; Ertesvåg, Helga; Valla, Svein; Skjåk-Bræk, Gudmund; Sletta, Håvard. (2013) Directed evolution, high throughput sceening and production of alginate-modifying enzymes with new and targeted properties. 3rd EPNOE International Polysaccharide Conference
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Conference posterLale, Rahmi; Ünver, Deniz; Ertesvåg, Helga; Moghadam, Morteza Shojaei; Valla, Svein. (2013) Cold-adapted (psychrophilic) marine bacteria as expression hosts. Bioprosp_13
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Conference posterErtesvåg, Helga. (2013) Azotobacter vinelandii encystment. FEMS 2013 5th congress of european microbiologists
2009
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Conference posterMærk, Mali; Lien, Stina Katrine; Ertesvåg, Helga; Bruheim, Per; Valla, Svein. (2009) An Entner-Doudoroff pathway mutation in Pseudomonas fluorescens causes cell death during alginate production. The Norwegian Biochemical Society 45th Contact Meeting
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Conference posterMærk, Mali; Ellingsen, Trond E.; Ertesvåg, Helga; Jakobsen, Øyvind M.; Klinkenberg, Geir; Sletta, Håvard; Tøndervik, Anne; Valla, Svein. (2009) Bacterial alginate biosynthesis: New genes identified by high-throughput screening. 10th International Conference on Systems Biology
2008
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Conference posterErtesvåg, Helga; Mærk, Mali; Jakobsen, Øyvind M.; Vie, Ane Kjersti; Sletta, Håvard. (2008) Identification of genes involved in alginate production and encystment in Azotobacter vinelandii. 9th International Conference on Systems Biology
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Conference posterMærk, Mali; Jakobsen, Øyvind M.; Ertesvåg, Helga; Sletta, Håvard; Klinkenberg, Geir; Ellingsen, Trond E.; Valla, Svein. (2008) New genes affecting alginate biosynthesis in Azotobacter vinelandii. 33rd FEBS Congress & 11th IUBMB Conference "Biochemistry of Cell Regulation"
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Conference posterMærk, Mali; Jakobsen, Øyvind M.; Ertesvåg, Helga; Sletta, Håvard; Klinkenberg, Geir; Ellingsen, Trond E.; Valla, Svein. (2008) New genes affecting alginate biosynthesis in Azotobacter vinelandii. 8th FEBS Young Scientist Forum "Cell Harmony"
2006
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Conference lectureErtesvåg, Helga. (2006) Azotobacter vinelandii cysts. National Conference on Microbial Sciences and Technology
2005
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Conference posterGimmestad, Martin; Steigedal, Magnus; Christensen, Bjørn Erik; Sletta, Håvard; Ellingsen, Trond E; Valla, Svein; Ertesvåg, Helga. (2005) Identification and characterization of an Azotobacter vinelandii Type I secretion system responsible for export of the AlgE-type mannuronan C5-epimerase. 2nd European Conference on Prokaryotic Genomes. PROKAGEN 2005
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Conference posterErtesvåg, Helga; Sletta, Håvard; Bakkevig, Karianne; Degnes, Kristin F; Jørgensen, Hanne; Bakke, Ingrid; Ellingsen, Trond E; Valla, Svein. (2005) The use of inducible promoters to study the biosynthesisof alginate in Pseudomonas fluorescens. Pseudomonas 10th International Congress
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Conference lectureGimmestad, Martin; Ertesvåg, Helga; Bergene, N.I.; Svanem, Britt Iren Glærum; Bjerkan, Tonje Marita; Valla, Svein. (2005) Characterization of alginate lyases from the alginate-producing bacteria Azotobacter vinelandii and Pseudomonas fluorescens. The Norwegian Biochemical Society 41st Contact Meeting
2004
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Conference lectureErtesvåg, Helga; Valla, Svein. (2004) The use of metabolic engineering to study the biosynthesis of alginate in Pseudomonas fluorescens. Marine Biopolymers
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Conference lectureBjerkan, Tonje Marita; Bender, Carol; Ertesvåg, Helga; Drabløs, Finn; Fakhr, Mohamed K.; Preston, Lori A.; Skjåk-Bræk, Gudmund; Valla, Svein. (2004) The Pseudomonas syringae genome encodes a combined Mannuronan C-5-epimerase and O-acetylhydrolase, which strongly enhances the predicted gel-forming properties of alginates. National Conference on Microbial Sciences and Technology
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Conference posterBjerkan, Tonje Marita; Rozeboom, H.J.; Kalk, K.H.; Ertesvåg, Helga; Valla, Svein; Dijkstra, B.W.. (2004) The crystal structure of the catalytic A-module of AlgE4, a mannuronan C-5 epimerase from Azotobacter vinelandii. Marine Biopolymers
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Conference posterGimmestad, Martin; Bakkevig, Kari Anne; Sletta, Håvard; Ertesvåg, Helga; Skjåk-Bræk, Gudmund; Ellingsen, Trond Erling; Valla, Svein. (2004) The Pseudomonas fluorescens AlgG protein, but not its mannuronan C-5-epimerase activity, is needed for alginate polymer formation. Vintermøte 2004
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Conference posterSvanem, Britt Iren Glærum; Steigedal, Magnus; Klinkenberg, Geir; Ertesvåg, Helga; Skjåk-Bræk, Gudmund; Valla, Svein. (2004) Creating mannuronan C-5-epimerases with new properties by directed enzyme evolution. Vintermøte 2004
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Conference posterGimmestad, Martin; Ertesvåg, Helga; Svanem, Britt Iren Glærum; Valla, Svein. (2004) Characterisation of four novel alginate lyases from the alginate-producing bacteria Azotobacter vinelandii and Pseudomonas fluorescens. Marine Biopolymers
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Conference posterSvanem, Britt Iren Glærum; Steigedal, Magnus; Klinkenberg, Geir; Aakvik, Trine; Ertesvåg, Helga; Skjåk-Bræk, Gudmund; Valla, Svein. (2004) Creating mannuronan C-5 epimerases with new properties by directed enzyme evolution. Marine Biopolymers
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Conference posterGimmestad, Martin; Bakkevig, Kari Anne; Sletta, Håvard; Ertesvåg, Helga; Skjåk-Bræk, Gudmund; Ellingsen, Trond Erling; Valla, Svein. (2004) The Pseudomonas fluorescens AlgG protein, but not its mannuronan C-5 epimerase activity, is needed for alginate polymer formation. Marine Biopolymers
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Conference lectureErtesvåg, Helga; Bakkevig, Kari Anne; Sletta, Håvard; Degnes, K.F.; Ellingsen, Trond Erling; Valla, Svein. (2004) The use of metabolic engineering to study the biosynthesis of alginate in Pseudomonas fluorescens. Marine Biopolymers
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Conference lectureDegelmann, A.; Sletta, Håvard; Ertesvåg, Helga; Valla, Svein; Onsøyen, E.; Piontek, M.. (2004) Secreted expression of a bacterial alginate epimerase in Hansenula polymorpha: pitfalls and solutions. Industrial Microbiology and Biotechnology Meeting
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Conference lectureGimmestad, Martin; Ertesvåg, Helga; Svanem, Britt Iren Glærum; Valla, Svein. (2004) Use of the Azotobacter vinelandii genome sequence. eller Gene mining in the Azotobacter vinelandii genome. Vintermøte 2004
2003
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Conference posterSvanem, B I G.; Steigedal, Magnus; Klinkenberg, Geir; Ertesvåg, Helga; Skjåk-Bræk, Gudmund; Valla, Svein. (2003) Creating mannuronan C-5-epimerases with new properties using directed enzyme evolution. 11th European Congress on Biotechnology
2002
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Conference lectureBjerkan, Tonje Marita; Ertesvåg, Helga; Valla, Svein. (2002) Use of a conditional suicide vector to study the effect of AlgE7 on the encystment and germination of Azetobacter vinelandii. NBS kontaktmøte
1998
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LectureSvanem, Britt Iren Glærum; Ertesvåg, Helga; Valla, Svein. (1998) Cloning and expression of the last three mannuronan C-5-epimerase genes of the algE-gene family of Azotobacter vinelandii. 34. Biokjemiske Kontaktmøte, NBS
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Conference lectureErtesvåg, Helga; Valla, Svein. (1998) Mannuronan C-5-epimerasar kontrollerer eigenskapane til alginat. Polymer- og kolloidvitenskapelig vårmøte 1998
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Conference posterErtesvåg, Helga; Høidal, Hilde Kristin; Valla, Svein. (1998) Characterization of the modular mannuronan C-5-epimerase AlgE1 from Azotobacter vinelandii. 8th International Symposium on the Genetics of Industrial Micro organisms
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Conference lectureSvanem, B I G.; Ertesvåg, Helga; Valla, Svein. (1998) Cloning and expression of the last three mannuronan C-5-epimerase genes of the algE-gene family of Azotobacter vinelandii. 34. Biokjemiske Kontaktmøte, NBS
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Conference posterErtesvåg, Helga; Høidal, Hilde K.; Valla, Svein. (1998) Characterization of the modular mannuronan C-5-epimerase AlgE1 from Azotobacter vinelandii. 8th International Symposium On The Genetics Of Industrial Microorganisms
1997
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Conference posterErtesvåg, Helga; Høidal, Hilde Kristin; Valla, Svein. (1997) Mannuronan C-5-epimerases a family of modular proteins. 2nd Carbohydrate Bioengineering Meeting
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LectureValla, Svein; Ertesvåg, Helga; Høidal, Hilde Kristin; Glærum, Britt Iren. (1997) How azotobacter vinelandii uses a family of mannuronan C-5-epimerases to control the physical properties of its alginate. Eurocarb 9
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Conference lectureErtesvåg, Helga; Høidal, Hilde Kristin; Glærum, Britt Iren; Valla, Svein. (1997) Mannuronan C-5-epimerases from Azotobacter vinelandii. INPEC-97, International Network of Protein Engineering Centres Annual Meeting
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Conference lectureErtesvåg, Helga; Høidal, Hilde Kristin; Glærum, Britt Iren; Valla, Svein. (1997) Mannuronan C-5-epimerases from Azotobacter vinelandii. Biokjemiske kontaktmøte, NBS
1994
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Conference lectureErtesvåg, Helga; Doseth, B.; Larsen, Bjørn; Skjåk-Bræk, Gudmund; Høidal, Hilde; Hals, Ingrid; Budal, Leiv; Valla, Svein. (1994) A family of genes encoding mannuronan C5-epimerase in Azotobacter vinelandii. 1st International Conference on Polysaccharide Engineering