Course - Prokaryote Molecular Biology and Synthetic Biology - BT8120
BT8120 - Prokaryote Molecular Biology and Synthetic Biology
Lessons are not given in the academic year 2023/2024
The course is offered every alternate year, next time spring 2025. The course will cover the following topics within basic procaryote molecular biology and physiology and synthetic biology:
- Gene expression and regulation
- Growth and Bioenergetics
- Coordination and regulation of microbial metabolism
- Cell differentiation
- Cell communication and interactions
- Secondary metabolism
- Genetic circuits
- Design, construction and expression of synthetic pathways
- Genetic engineering techniques and tool boxes
- Synthetic genomes and gene editing
- Omics technologies (Genome and transcriptomics; Proteomics; Metabolomics, Fluxomics and lipid)
The objective of the course is to provide an understanding of the physiology of the microbial cell and how it can be manipulated. Topics that are important for synthetic biology are emphasized. The second part focuses on the approaches and tools directly utilized in synthetic biology. After the course, the student will have acquired fundamental knowledge of procaryote molecular biology and physiology at an advanced level, and be able to analyze given problems and suggest how they may be solved. For the topics on genetic circuits and on -omics technologies, the aim is to provide the students with the understanding of what these approaches may contribute to a project.
Learning methods and activities
Topics in this course will be presented using new literature, lectures and discussions. The students will further be given a Paper to present as poster or orally. The course will be given in English and the exam will be given in English only. The lectures will be concentrated on 3 + 3 days (a total of 36 hours). In addition the students must expect 144 hours self study and 16 hours working on the presentation.
Further on evaluation
Group based work will be presented and counts 20 %. The final, individual written semester test 80 %. In case of few students the semester test may be changed to an oral test.
Recommended previous knowledge
The course builds on advanced knowledge in biochemistry (TBT4102 + TBT4107 or similar), microbiology (TBT4110 or similar) and molecular genetics (TBT4145/TBT4146 or similar).
Provided at the beginning of the course.
Credits: 7.5 SP
Study level: Doctoral degree level
Language of instruction: English
- Technological subjects
Department with academic responsibility
Department of Biotechnology and Food Science
- * The location (room) for a written examination is published 3 days before examination date. If more than one room is listed, you will find your room at Studentweb.
For more information regarding registration for examination and examination procedures, see "Innsida - Exams"