Mari Løset
Background and activities
I work as a Postdoctoral Fellow at K.G. Jebsen Center for Genetic Epidemiology, NTNU, and as a Clinical Resident at Department of Dermatology, St. Olavs hospital, Trondheim, Norway. I’m interested to learn more about how genes contribute to the development of inflammatory skin diseases, including psoriasis and atopic dermatitis. My work includes genetic studies using data from the Nord-Trøndelag Health Study (HUNT) in combination with regional- and national health registries, and RNA sequencing data from psoriasis-related skin samples. In my group we aim to reveal novel mechanisms for disease development and to translate these insights into prevention strategies and treatments.
You can read more about our ongoing projects and collaborations here:
Uttrykksfull hud – Genuttrykk ved psoriasis
Genetisk informasjon kan bidra til ny og mer målrettet behandling av psoriasis
Høyere vekt øker risikoen for psoriasis - forskning.no
Genetisk disposisjon for atopisk dermatitt - BestPractice Nordic
Scientific, academic and artistic work
Displaying a selection of activities. See all publications in the database
2020
- (2020) Age-of-onset information helps identify 76 genetic variants associated with allergic disease. PLoS Genetics. vol. 16 (6).
- (2020) Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease. Nature Communications.
2019
- (2019) Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study. Nature Methods. vol. 16:e1002739 (1).
- (2019) Genetics of Atopic Dermatitis: From DNA Sequence to Clinical Relevance. Dermatology. vol. 235 (5).
- (2019) Differentially Expressed miRNAs and mRNAs in Psoriatic Skin. American Society for Human Genetics Annual Meeting . American Society for Human Genetics; Houston, TX. 2019-10-15 - 2019-10-19.
- (2019) Genome-wide association study of psoriasis suggests a new risk locus on chromosome 10: The HUNT Study. The 34th Nordic Congress of Dermatology & Venereology ; Gøteborg. 2019-05-08 - 2019-05-10.
- (2019) Genome-wide association study of psoriasis suggests a new risk locus on chromosome 10: The HUNT Study. Forum for Nordic Dermato-Venereology. vol. 24 (2).
- (2019) Combined mRNA and miRNA Analysis of Psoriatic Skin. The 34th Nordic Congress of Dermatology & Venereology ; Gøteborg. 2019-05-08 - 2019-05-10.
- (2019) Differentially Expressed miRNAs and mRNAs in Psoriatic Skin. European Society for Dermatological Research Annual Meeting . European Society for Dermatological Research; Bordeaux. 2019-09-18 - 2019-09-21.
- (2019) Combined mRNA and miRNA Analysis of Psoriatic Skin. Forum for Nordic Dermato-Venereology. vol. 24 (2).
- (2019) Differentially Expressed miRNAs and mRNAs in Psoriatic Skin. Journal of Investigative Dermatology. vol. 139 (9S).
- (2019) Høyere vekt øker risikoen for psoriasis. Gemini [Fagblad]. 2019-05-01.
2018
- (2018) 743 HUNTing for genes that affect inflammatory skin disease in 4,071 cases and 40,430 controls. Journal of Investigative Dermatology. vol. 138 (5).
2017
- (2017) Brikker i et gigantisk puslespill. Hud & Helse [Tidsskrift]. 2017-09-01.
- (2017) Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology. Nature Genetics. vol. 49 (12).
- (2017) Genetisk informasjon kan bidra til ny og mer målrettet behandling av psoriasis.
2016
- (2016) HUNTing for Genes that Affect Psoriasis in ~2,900 Cases and ~48,000 Controls. The 33rd Nordic Congress of Dermatology and Venereolgy ; 2016-04-27 - 2016-04-29.
- (2016) HUNTing for Genes that Affect Psoriasis in ~2,900 Cases and ~48,000 Controls. Forum for Nordic Dermato-Venereology. vol. 21 (1).
- (2016) Establishing a biobank for gene expression studies of psoriasis. Frampeik ; Bergen. 2016-10-21 - 2016-10-23.
2014
- (2014) Genetic predisposition to preeclampsia. Genetic association studies on population-based cohorts and transcriptional studies on decidua basalis tissue. Tapir Akademisk Forlag. 2014. Doktoravhandlinger ved NTNU (47).
- (2014) Genetisk disposisjon for utvikling av preeklampsi. Tidsskrift for Den norske legeforening.
- (2014) Preeclampsia and cardiovascular disease share genetic risk factors on chromosome 2q22. Pregnancy Hypertension. vol. 4 (2).
2013
- (2013) Svangerskap og hjertehelse. Bergens Tidende.
- (2013) A SNP associated with susceptibility to preeclampsia near the Inhibin, beta B gene, is also associated with cardiovascular disease risk traits. European Congress of the International Society for the Study of Hypertension in Pregnancy ; Tromsø. 2013-06-12 - 2013-06-14.
- (2013) A SNP associated with susceptibility to preeclampsia near the Inhibin, beta B gene, is also associated with cardiovascular disease risk traits. Pregnancy Hypertension. vol. 3 (2).
2012
- (2012) Exome sequencing identifies likely functional variants influencing preeclampsia and CVD risk. Pregnancy Hypertension 2012: Vol. 2, Issue 3, Pages 203-204 ; 2012-07-09 - 2012-07-12.
- (2012) Shared genetic risk factors for preeclapmsia and cardiovascular disease. The XVIII ISSHP World Congress . ISSHP; Geneva. 2012-07-09 - 2012-07-12.
- (2012) Shared genetic risk factors for preeclampsia and cardiovascular disease. Pregnancy Hypertension. vol. 2 (3).
2011
- (2011) A transcriptional profile of the decidua in preeclampsia. American Journal of Obstetrics and Gynecology. vol. 204 (1).
- (2011) Partial correlation network analyses to detect altered gene interactions in human disease: using preeclampsia as a model. Human Genetics. vol. 129 (1).
- (2011) Increased endoplasmic reticulum stress in decidual tissue from pregnancies complicated by fetal growth restriction with and without pre-eclampsia. Placenta. vol. 32 (11).
- (2011) Endoplasmic reticulum stress in decidual tissue from pregnancies complicated by pre-eclampsia and fetal growth restriction. Placenta. vol. 32 (9).
- (2011) Endoplasmic reticulum stress in decidual tissue from pregnancies complicated by pre-eclampsia and fetal growth restriction. 14th European Placenta Group Meeting ; Geilo. 2011-09-14 - 2011-09-18.
- (2011) Increased endoplastic reticulum stress in decidual tissue from pregnancies complicatad by fetal growth restriction with and without pre-eclampsia. Placenta.
- (2011) Shared genetic risk factors for preeclampsia and cardiovascular disease. Group meeting . Raine Cardiovascular Group, School of Medicine and Pharmacol; Perth. 2011-09-29 - 2011-09-29.
- (2011) Shared genetic risk factors for preeclampsia and cardiovascular disease. Group meeting . School of Chemistry and Biochemistry, The University of West; Perth. 2011-12-12 - 2011-12-12.
- (2011) Exome sequencing in preeclampsia. Information session honours project . School of Pathology and Laboratory Medicine University of We; Perth. 2011-10-05 - 2011-10-05.
2010
- (2010) STOX2 but not STOX1 is differently expressed in preeclampstic decidua from Norwegian women: data from the Second Nord-Trondelag Health Study. Molecular human reproduction. vol. 16 (12).
- (2010) Endoplasmatic reticulum stress in decidual tissue from pregnancies complicated with preeclampsia. Hypertension in Pregnancy. vol. 1.
- (2010) Endoplasmic reticulum stress in decidual tissue from pregnancies complicated by pre-eclampsia. XVII World Congress of the International Society for the Study of Hypertension in Pregnancy (ISSHP 2010) ; Melbourne. 2010-10-03 - 2010-10-06.
- (2010) A transcriptional profile of the decidua in preeclampsia. 2010.
- (2010) Gener og reaksjonsveier knyttet til preeklampsi. Tidsskrift for Den norske legeforening.
2009
- (2009) Genome wide expression profiling in decidua identifies novel endoplasmic reticulum stress regulating genes involved in preeclampsia. Frampeik 2009 ; Oslo universitetssykehus Rikshospitalet. 2009-10-30 - 2009-11-01.
- (2009) Genome-Wide Differntial Decidual Gene Expression and Pathway Analysis in Preeclampsia. Frampeik 2009 ; Oslo universitetssykehus Rikshospitalet. 2009-10-30 - 2009-11-01.
- (2009) Forskningsdagene 2009. Forskningstorget [TV]. 2009-09-25.
2007
- (2007) Genetic association of pre-eclampsia to the inflammatory response gene, SEPS1. Eur ISSHP Conference . International Society for Hypertension in Pregnancy; Reykjavik. 2007-05-25 - 2007-05-27.
- (2007) Association between SEPS1 G-105A promoter polymorphism and pre-eclampsia. IFPA 2007 . International Fedreration of Placental associations; Kingston. 2007-08-17 - 2007-08-22.
- (2007) Association of pre-eclampsia to the inflammatory response gene SEPS1 G-105A polymorphism and pre-eclampsia in a Norwegian population. 3rd International Meeting on Genetics of Complex Diseases and Isolated populations . Fondazione per le Biotechnologie; Torino. 2007-05-27 - 2007-05-30.
- (2007) Association between SEPS1 G-105A promotor polymorphism and pre-eclampsia. Placenta. vol. 28.