Wetlab services

GCF provides a broad portfolio of DNA and RNA sequencing services using state-of-the-art Next Generation Sequencing (NGS) platforms, including Illumina NovaSeq 6000, NextSeq 500, MiSeq and MiniSeq.

NGS applications include:

• de novo genome sequencing
• Whole-genome and targeted resequencing
• Whole-exome sequencing
• Transcriptome profiling (bulk RNA-seq), including isoform detection and small RNA sequencing
• ChIP-seq for mapping genome-wide transcription factor binding sites
• Metagenomic analysis of microbiome samples

GCF has also established single-cell and single-nucleus sequencing and spatial transcriptomics using 10x Genomics and Parse Biosciences technologies.

In addition, we offer large-scale DNA microarray analysis (SNP genotyping and DNA methylation) using the Illumina iScan system, supported by Tecan liquid-handling automation.

GCF also provides Proteomics-by-Genomics analysis through Olink technology, enabling multiplexed protein biomarker profiling in combination with genomic data.

RNA/DNA Sample Preparation and Quality Control

High-quality DNA and RNA are essential for generating reliable sequencing and array data. Please refer to our general guidelines for sample preparation and DNA/RNA quality control.

For assistance with DNA/RNA extraction, we recommend contacting BioBank1 at Helse Midt-Norge, who can provide professional support and extraction services.

Bioinformatics services

Modern genome analysis depends on strong computational expertise. GCF integrates bioinformatics directly with the wetlab services to ensure efficient data handling, quality control, and advanced analysis.

Our bioinformaticians assist with:

• Experimental planning and study design
• Data processing and QC
• Statistical and computational analysis
• Interpretation of sequencing and multi-omics datasets

Because many users lack specialized expertise in genomics data analysis, our team provides essential support at every stage to ensure robust scientific outcomes.