Publications associated with Genomics Core Facility (GCF) and the previous FUGE Microarray Platform (NMC)

2017

Pål Vange, Torunn Bruland, Berit Doseth, Reidar Fossmark, Mirta M. L. Sousa, Vidar Beisvag, Øystein Sørdal, Gunnar Qvigstad, Helge L. Waldum, Arne K. Sandvik, Ingunn Bakke. The cytoprotective protein clusterin is overexpressed in hypergastrinemic rodent models of oxyntic preneoplasia and promotes gastric cancer cell survival. PloS one 12 (9)September 13, 2017

 

Skogholt AH, Ryeng E, Erlandsen SE, Skorpen F, Schønberg SA, Sætrom P. Gene expression differences between PAXgene and Tempus blood RNA tubes are highly reproducible between independent samples and biobanks. BMC Res Notes. 2017 Mar 23;10(1):136.

 

Even Holth Rustad, Eivind Coward, Emilie R Skytøen, Kristine Misund, Toril Holien, Therese Standal, Magne Børset, Vidar Beisvag, Ola Myklebost, Leonardo A Meza-Zepeda, Hong Yan Dai, Anders Sundan, Anders Waage. Monitoring of multiple myeloma by quantification of recurrent mutations in serum
Haematologica, 4/6 2017.

 

Olsen LC, O'Reilly KC, Liabakk NB, Witter MP, Sætrom P. MicroRNAs contribute to postnatal development of laminar differences and neuronal subtypes in the rat medial entorhinal cortex. Brain Struct Funct. 2017 Mar 4

 

Webb TR, Holmen OL, Hveem K et al. Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease. J Am Coll Cardiol. 2017 Feb 21;69(7):823-836.

 

Marouli E, Holmen OL, Hveem K et al. Rare and low-frequency coding variants alter human adult height. Nature. 2017 Feb 9;542(7640):186-190.

 

2016

Kristin M Aasarød, Masoud Ramezanzadehkoldeh, Maziar Shabestari, Mats P Mosti, Astrid K Stunes, Janne E Reseland, Vidar Beisvag, Erik Fink Eriksen, Arne K Sandvik, Reinhold G Erben, Christiane Schüler, Malcolm Boyce, Bjørn H Skallerud, Unni Syversen, Reidar Fossmark. Skeletal effects of a gastrin receptor antagonist in H+/K+ ATPase beta subunit KO mice. Journal of Endocrinology 230 (2), 251-262, 2016.

 

Eikrem OS, Strauss P, Beisland C, Scherer A, Landolt L, Flatberg A, Leh S, Beisvag V, Skogstrand T, Hjelle K, Shresta A, Marti HP. Development and confirmation of potential gene classifiers of human clear cell renal cell carcinoma using next-generation RNA sequencing. Scand J Urol. 2016 Dec;50(6):452-462.

 

Zayats T, Holmen OL et al. Exome chip analyses in adult attention deficit hyperactivity disorder. Transl Psychiatry. 2016 Oct 18;6(10)

 

Ehret GB, Kvaløy K, Holmen OL, Hveem K et al. The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nat Genet. 2016 Oct;48(10):1171-84

 

Surendran P, Holmen OL, Hveem K et al. Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension. Nat Genet. 2016 Oct;48(10):1151-61.

 

Eftedal I, Flatberg A, Drvis I, Dujic Z. Immune and inflammatory responses to freediving calculated from leukocyte gene expression profiles. Physiol Genomics. 2016 Nov 1;48(11):795-802

 

Landolt L, Marti HP, Beisland C, Flatberg A, Eikrem OS. RNA extraction for RNA sequencing of archival renal tissues. Scand J Clin Lab Invest. 2016 Sep;76(5):426-34.

 

Bhandari S, Bakke I, Kumar J, Beisvag V, Sandvik AK, Thommesen L, Varro A, Nørsett KG. Connective tissue growth factor is activated by gastrin and involved in gastrin-induced migration and invasion. Biochem Biophys Res Commun. 2016 Jun 17;475(1):119-24.

 

Fossmark R, Rao S, Mjønes P, Munkvold B, Flatberg A, Varro A, Thommesen L, Nørsett KG. PAI-1 deficiency increases the trophic effects of hypergastrinemia in the gastric corpus mucosa. Peptides. 2016 May;79:83-94.

 

Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators., Stitziel NO, Holmen OL, Hveem K et al. Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. N Engl J Med. 2016 Mar 24;374(12):1134-44

 

Eikrem O, Beisland C, Hjelle K, Flatberg A, Scherer A, Landolt L, Skogstrand T, Leh S, Beisvag V, Marti HP. Transcriptome Sequencing (RNAseq) Enables Utilization of Formalin-Fixed, Paraffin-Embedded Biopsies with Clear Cell Renal Cell Carcinoma for Exploration of Disease Biology and Biomarker Development. PLoS One. 2016 Feb 22;11(2).

 

2015

Tang CS, Holmen OL, Hveem K et al. Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese. Nat Commun. 2015 Dec 22;6.

 

Simpson MR, Brede G, Johansen J, Johnsen R, Storrø O, Sætrom P, Øien T. Human Breast Milk miRNA, Maternal Probiotic Supplementation and Atopic Dermatitis in Offspring. PLoS One. 2015 Dec 14;10(12)

 

Gaulton KJ, Holmen OL, Hveem K et al.Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci. Nat Genet. 2015 Dec;47(12)


Pettersen K, Monsen VT, Hakvåg Pettersen CH, Overland HB, Pettersen G, Samdal H, Tesfahun AN, Lundemo AG, Bjørkøy G, Schønberg S.DHA-induced stress response in human colon cancer cells - Focus on oxidative stress and autophagy. Free Radic Biol Med. 2015 Nov 14


Skovdahl HK, Granlund Av, Østvik AE, Bruland T, Bakke I, Torp SH, Damås JK, Sandvik AK. Expression of CCL20 and Its Corresponding Receptor CCR6 I Enhanced in Active Inflammatory Bowel Disease, and TLR3 Mediates CCL20 Expression in Colonic Epithelial Cells. PLoS One. 2015 Nov 4;10(11)


Winkler TW, Holmen OL, Hveem K et al. The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet. 2015 Oct 1;11(10)


Johansson I, Monsen VT, Pettersen K, Mildenberger J, Misund K, Kaarniranta K, Schønberg S, Bjørkøy G. The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells. Autophagy. 2015 Sep 2;11(9):1636-51.


Vange P, Bruland T, Beisvag V, Erlandsen SE, Flatberg A, Doseth B, Sandvik AK, Bakke I.Genome-wide analysis of the oxyntic proliferative isthmus zone reveals ASPM as a possible gastric stem/progenitor cell marker over-expressed in cancer. J Pathol. 2015 Jul 16


Brenna Ø, Bruland T, Furnes MW, Granlund AV, Drozdov I, Emgård J, Brønstad G, Kidd M, Sandvik AK, Gustafsson BI.The guanylate cyclase-C signaling pathway is down-regulated in inflammatory bowel disease. Scand J Gastroenterol. 2015 May 15:1-12.


Hansen MF, Johansen J, Bjørnevoll I, Sylvander AE, Steinsbekk KS, Sætrom P, Sandvik AK, Drabløs F, Sjursen W. A novel POLE mutation associated with cancers of colon, pancreas, ovaries and small intestine. Fam Cancer. 2015 Apr 10.


Rustad EH, Dai HY, Hov H, Coward E, Beisvag V, Myklebost O, Hovig E, Nakken S, Vodák D, Meza-Zepeda LA, Sandvik AK, Wader KF, Misund K, Sundan A, Aarset H, Waage A. BRAF V600E mutation in early-stage multiple myeloma: good response to broad acting drugs and no relation to prognosis. Blood Cancer J. 2015 Mar 20;5:e299.


Dumeaux V, Ursini-Siegel J, Flatberg A, Fjosne HE, Frantzen JO, Holmen MM, Rodegerdts E, Schlichting E, Lund E. Peripheral blood cells inform on the presence of breast cancer: a population-based case-control study. Int J Cancer. 2015 Feb 1;136(3):656-67.


Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH,et al. Genetic studies of body mass index yield new insights for obesity biology. Nature. 2015 Feb 12;518(7538):197-206.


Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, et al. New genetic loci link adipose and insulin biology to body fat distribution. Nature. 2015 Feb 12;518(7538):187-96.

 

 

2014

 

Wood AR, Esko T, Yang J, Vedantam S, Pers TH, et al.Defining the role of common variation in the genomic and biological architecture of adult human height. Nat Genet. 2014 Nov;46(11):1173-86.

Zhao CM, Kodama Y, Flatberg A, Beisvag V, Kulseng B, Sandvik AK, Rehfeld JF, Chen D. Gene expression profiling of gastric mucosa in mice lacking CCK and gastrin receptors. Regul Pept. 2014 Jun-Aug;192-193:35-44.

 

Zhao CM, Hayakawa Y, Kodama Y, Muthupalani S, Westphalen CB, Andersen GT, Flatberg A, Johannessen H, Friedman RA, Renz BW, Sandvik AK, Beisvag V, Tomita H, Hara A, Quante M, Li Z, Gershon MD, Kaneko K, Fox JG, Wang TC, Chen D. Denervation suppresses gastric tumorigenesis. Sci Transl Med. 2014 Aug 20;6(250.

 

O'Reilly KC, Flatberg A, Islam S, Olsen LC, Kruge IU, Witter MP. Identification of dorsal-ventral hippocampal differentiation in neonatal rats. Brain Struct Funct. 2014 Jul 11.

 

Holmen OL, Zhang H, Fan Y, Hovelson DH, Schmidt EM, Zhou W, Guo Y, Zhang J, Langhammer A, Løchen ML, Ganesh SK, Vatten L, Skorpen F, Dalen H, Zhang J, Pennathur S, Chen J, Platou C, Mathiesen EB, Wilsgaard T, Njølstad I, Boehnke M, Chen YE, Abecasis GR, Hveem K, Willer CJ. Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk. Nat Genet. 2014 Apr;46(4):345-51.

 

Razick S, Mocnik R, Thomas LF, Ryeng E, Drabløs F, Sætrom P. The eGenVar data management system--cataloguing and sharing sensitive data and metadata for the life sciences. Database (Oxford). 2014 Mar 28;2014

 

Myhrstad MC, Ulven SM, Günther CC, Ottestad I, Holden M, Ryeng E, Borge GI, Kohler A, Brønner KW, Thoresen M, Holven KB. Fish oil supplementation induces expression of genes related to cell cycle, endoplasmic reticulum stress and apoptosis in peripheral blood mononuclear cells: a transcriptomic approach. J Intern Med. 2014 Nov;276(5):498-511.

 

Agdestein A, Jones A, Flatberg A, Johansen TB, Heffernan IA, Djønne B, Bosco A, Olsen I1. Intracellular growth of Mycobacterium avium subspecies and global transcriptional responses in human macrophages after infection. BMC Genomics. 2014 Jan 23;15:58.

 

 

2013

 

Granlund Av, Flatberg A, Østvik AE, Drozdov I, Gustafsson BI, Kidd M, Beisvag V, Torp SH, Waldum HL, Martinsen TC, Damås JK, Espevik T, Sandvik AK. Whole genome gene expression meta-analysis of inflammatory bowel disease colon mucosa demonstrates lack of major differences between Crohn's disease and ulcerative colitis. PLoS One. 2013;8(2):e56818.

 

Ostvik AE, Granlund AV, Bugge M, Nilsen NJ, Torp SH, Waldum HL, Damås JK, Espevik T, Sandvik AK. Enhanced expression of CXCL10 in inflammatory bowel disease: potential role of mucosal Toll-like receptor 3 stimulation. Inflamm Bowel Dis. 2013 Feb;19(2):265-74.

 

Misund K, Selvik LK, Rao S, Nørsett K, Bakke I, Sandvik AK, Lægreid A, Bruland T, Prestvik WS, Thommesen L. NR4A2 Is Regulated by Gastrin and Influences Cellular Responses of Gastric Adenocarcinoma Cells. PLoS One. 2013 Sep 27;8(9):e76234.

 

Brenna Ø, Furnes MW, Drozdov I, van Beelen Granlund A, Flatberg A, Sandvik AK, Zwiggelaar RT, Mårvik R, Nordrum IS, Kidd M, Gustafsson BI. Relevance of TNBS-colitis in rats: a methodological study with endoscopic, histologic and Transcriptomic characterization and correlation to IBD. PLoS One. 2013;8(1):e54543.

 

Eftedal I, Ljubkovic M, Flatberg A, Jørgensen A, Brubakk AO, Dujic Z. Acute and potentially persistent effects of scuba diving on the blood transcriptome of experienced divers. Physiol Genomics. 2013 Oct 16;45(20):965-72.

 

Østvik AE, Granlund AV, Torp SH, Flatberg A, Beisvåg V, Waldum HL, Flo TH, Espevik T, Damås JK, Sandvik AK. Expression of Toll-like receptor-3 is enhanced in active inflammatory bowel disease and mediates the excessive release of lipocalin 2. Clin Exp Immunol. 2013 Sep;173(3):502-11.

 

Brattbakk HR, Arbo I, Aagaard S, Lindseth I, de Soysa AK, Langaas M, Kulseng B, Lindberg F, Johansen B. Balanced caloric macronutrient composition downregulates immunological gene expression in human blood cells-adipose tissue diverges. OMICS. 2013 Jan;17(1):41-52.

 

Berg K, Langaas M, Ericsson M, Pleym H, Basu S, Nordrum IS, Vitale N, Haaverstad R.

Acetylsalicylic acid treatment until surgery reduces oxidative stress and inflammation in patients undergoing coronary artery bypass grafting. Eur J Cardiothorac Surg. 2013 Jun;43(6):1154-63.

 

Selvik LK, Fjeldbo CS, Flatberg A, Steigedal TS, Misund K, Anderssen E, Doseth B, Langaas M, Tripathi S, Beisvag V, Lægreid A, Thommesen L, Bruland T. The duration of gastrin treatment affects global gene expression and molecular responses involved in ER stress and anti-apoptosis. BMC Genomics. 2013 Jun 28;14:429.

 

 

2012

 

Røe, Oluf Dimitri; Szulkin, Adam; Anderssen, Endre; Flatberg, Arnar; Sandeck, Helmut; Amundsen, Tore; Erlandsen, Sten Even; Dobra, Katalin; Sundstrøm, Stein Harald.  Molecular Resistance Fingerprint of Pemetrexed and Platinum in a Long-Term Survivor of Mesothelioma. PLoS ONE 2012 ;Volume 7.(8)

 

Reinertsen, Tove; Halgunset, Jostein; Viset, Trond; Flatberg, Arnar; Haugsmoen, Linn Lervik; Skogseth, Haakon. Gene expressional changes in prostate fibroblasts from cancerous tissue. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS) 2012 ;Volume 120.(7) p. 558-571

 

Eftedal, Ingrid; Jørgensen, Arve; Røsbjørgen, Ragnhild; Flatberg, Arnar; Brubakk, Alf O. Early genetic responses in rat vascular tissue after simulated diving. Physiological Genomics 2012 ;Volume 44.(24) p. 1201-1207

 

Bertilsson, Helena; Tessem, May-Britt; Flatberg, Arnar; Viset, Trond; Gribbestad, Ingrid S; Angelsen, Anders; Halgunset, Jostein. Changes in Gene Transcription Underlying the Aberrant Citrate and Choline Metabolism in Human Prostate Cancer Samples. Clinical Cancer Research 2012 ;Volume 18.(12) p. 3261-3269

 

Fjeldbo CS, Bakke I, Erlandsen SE, Holmseth J, Lægreid A, Sandvik AK, Thommesen L, Bruland T. Gastrin upregulates the prosurvival factor secretory clusterin in adenocarcinoma cells and in oxyntic mucosa of hypergastrinemic rats. Am J Physiol Gastrointest Liver Physiol. 2012 Jan 1;302(1):G21-33.

 

 

2011

 

Granlund AB, Beisvag V, Torp SH, Flatberg A, Kleveland PM, Ostvik AE, Waldum HL, Sandvik AK. Activation of REG family proteins in colitis. Scand J Gastroenterol. 2011 Nov;46(11):1316-23.

 

Maple J, Winge P, Tveitaskog AE, Gargano D, Bones AM, Møller SG.Genome-wide gene expression profiles in response to plastid division perturbations. Planta. 2011 Nov;234(5):1055-63.

 

Lundemo AG, Pettersen CH, Berge K, Berge RK, Schønberg SA.Tetradecylthioacetic acid inhibits proliferation of human SW620 colon cancer cells - gene expression profiling implies endoplasmic reticulum stress. Lipids Health Dis. 2011 Oct 25;10:190.

 

Salvetti S, Faegri K, Ghelardi E, Kolstø AB, Senesi S. Global gene expression profile for swarming Bacillus cereus bacteria. Appl Environ Microbiol. 2011 Aug;77(15):5149-56. Epub 2011 Jun 3.

 

Kusnierczyk A, Tran DH, Winge P, Jørstad TS, Reese JC, Troczynska J, Bones AM.

Testing the importance of jasmonate signalling in induction of plant defences upon cabbage aphid (Brevicoryne brassicae) attack. BMC Genomics. 2011 Aug 19;12:423.

 

Doseth B, Visnes T, Wallenius A, Ericsson I, Sarno A, Pettersen HS, Flatberg A, Catterall T, Slupphaug G, Krokan HE, Kavli B. Uracil-DNA glycosylase in base excision repair and adaptive immunity: species differences between man and mouse. J Biol Chem. 2011 May 13;286(19):16669-80.

 

Jørgensen KM, Hjelle SM, Øye OK, Puntervoll P, Reikvam H, Skavland J, Anderssen E, Bruserud Ø, Gjertsen BT. Untangling the intracellular signalling network in cancer--a strategy for data integration in acute myeloid leukaemia. J Proteomics. 2011 Mar 1;74(3):269-81.

 

Vidar Beisvag, Audrey Kauffmann, James Malone, Carole Foy, Marc Salit, Heinz Schimmel5, Erik Bongcam-Rudloff, Ulf Landegren, Helen Parkinson, Wolfgang Huber, Alvis Brazma, Arne K. Sandvik and Martin Kuiper. Contributions of the EMERALD project to assessing and improving microarray data quality. BioTechniques 2011 Jan 50:27-31

 

 

2010

 

Slagsvold JE, Pettersen CH, Størvold GL, Follestad T, Krokan HE, Schønberg SA. DHA alters expression of target proteins of cancer therapy in chemotherapy resistant SW620 colon cancer cells. Nutr Cancer. 2010;62(5):611-21.

 

Hanne K. Skjeldam, Henok Kassahun, Øyvind Fensgård, Tanima SenGupta, Eshrat Babaie, Jessica M. Lindvall, Katarzyna Arczewska, Hilde Nilsen Loss of Caenorhabditis elegans UNG-1 uracil-DNA glycosylase affects apoptosis in response to DNA damaging agents DNA Repair (Amst). 2010 Aug 5;9(8):861-70.

 

Huuse EM, Jensen LR, Goa PE, Lundgren S, Anderssen E, Bofin A, Gribbestad IS, Bathen TF. Monitoring the Effect of Docetaxel Treatment in MCF7 Xenografts Using Multimodal In Vivo and Ex Vivo Magnetic Resonance Methods, Histopathology, and Gene Expression. Transl Oncol. 2010 Aug 1;3(4):252-63.

 

Arum CJ, Anderssen E, Viset T, Kodama Y, Lundgren S, Chen D, Zhao CM. Cancer immunoediting from immunosurveillance to tumor escape in microvillus-formed niche: a study of syngeneic orthotopic rat bladder cancer model in comparison with human bladder cancer. Neoplasia. 2010 Jun;12(6):434-42.

 

Arum CJ, Kodama Y, Rolim N, Widerøe M, Anderssen E, Viset T, Otterlei M, Lundgren S, Chen D, Zhao CM. A rat model of intravesical delivery of small interfering RNA for studying urinary carcinoma. World J Urol. 2010 Aug;28(4):479-85. Epub 2010 Apr 8.

 

Arum CJ, Anderssen E, Tømmerås K, Lundgren S, Chen D, Zhao CM. Gene Expression Profiling and Pathway Analysis of Superficial Bladder Cancer in Rats. Urology. 2010 Mar;75(3):742-9. Epub 2009 Aug 3.

 

Fensgård Ø, Kassahun H, Bombik I, Rognes T, Lindvall JM, Nilsen H. A two-tiered compensatory response to loss of DNA repair modulates aging and stress response pathways. Aging (Albany NY). 2010 Mar 31;2(3):133-59.

 

Bertilsson H, Angelsen A, Viset T, Anderssen E, Halgunset J. RNA quality in fresh frozen prostate tissue from patients operated with radical prostatectomy. Scand J Clin Lab Invest. 2010 Feb;70(1):45-53.

 

Røe OD, Anderssen E, Sandeck H, Christensen T, Larsson E, Lundgren S. Malignant pleural mesothelioma: Genome-wide expression patterns reflecting general resistance mechanisms and a proposal of novel targets. Lung Cancer. 2010 Jan;67(1):57-68.

 

Follestad T, Jørstad TS, Erlandsen SE, Sandvik AK, Bones AM, Langaas M.  A Bayesian hierarchical model for quantitative real-time PCR data. Stat Appl Genet Mol Biol., 2010;9(1)

 

Bertilsson H, Angelsen A, Viset T, Anderssen E, Halgunset J. RNA quality in fresh frozen prostate tissue from patients operated with radical prostatectomy. Scand J Clin Lab Invest2010 Feb;70(1):45-53.

 

Kissen R, Winge P, Tran DH, Jørstad TS, Størseth TR, Christensen T, Bones AM. Transcriptional profiling of an Fd-GOGAT1/GLU1 mutant in Arabidopsis thaliana reveals a multiple stress response and extensive  reprogramming of the transcriptome. BMC Genomics2010 Mar 22;11:190.

 

 

2009

 

Beisvag V, Kemi OJ, Arbo I, Loennechen JP, Wisløff U, Langaas M, Sandvik AK, Ellingsen Ø. Pathological and physiological hypertrophies are regulated by distinct gene programs.

Eur J Cardiovasc Prev Rehabil. 2009 Dec;16(6):690-7.

 

Røe OD, Anderssen E, Helge E, Pettersen CH, Olsen KS, Sandeck H, Haaverstad R, Lundgren S, Larsson E. Genome-wide profile of pleural mesothelioma versus parietal and visceral pleura: the emerging gene portrait of the mesothelioma phenotype.

PLoS One. 2009 Aug. 7 ;4(8):e6554.

 

Gro L Størvold, Karianne G Fleten, Cathrine G Olsen, Turid Follestad, Hans E Krokan and Svanhild A Schønberg. Docosahexaenoic acid activates some SREBP-2 targets independent of cholesterol and ER stress in SW620 colon cancer cells”. Lipids 2009 Aug. 44 (8), 673-683.

 

Jens E Slagsvold, Caroline H Hakvåg Pettersen, Turid Follestad, Hans E Krokan and Svanhild A Schønberg. The antiproliferative effect of eicosapentaenoic acid is caused by alterations in calcium homeostasis and activation of the unfolded protein response”. Lipids 2009 Feb. 44 (2), 103-113.

 

Sehic A, Khuu C, Risnes S, Osmundsen H. Differential gene expression profiling of the molar tooth germ in peroxisome proliferator-activated receptor-alpha (PPAR-alpha) knockout mouse and in wild-type mouse: molar tooth phenotype of PPAR-alpha knockout mouse. Eur J Oral Sci. 2009 Apr;117(2):93-104.

 

 

2008

 

Hofsli E, Wheeler TE, Langaas M, Laegreid A, Thommesen L. Identification of novel neuroendocrine-specific tumour genes. Br J Cancer. 2008 Oct 21;99(8):1330-9.

 

Bye A, Høydal MA, Catalucci D, Langaas M, Kemi OJ, Beisvag V, Koch LG, Britton SL, Ellingsen Ø, Wisløff U. Gene expression profiling of skeletal muscle in exercise-trained and sedentary rats with inborn high and low VO2max. Physiol Genomics. 2008 Nov. 12;35(3):213-21.

 

Nilsen AJ, Landin MA, Haug KH, Fonnum F, Berger U, Osmundsen H. Comparative hepatic gene expression profiling of rats treated with 1H,1H,2H,2H-heptadecafluorodecan-1-ol or with pentadecafluorooctanoic acid. Physiol Genomics. 2008 Aug. 15;34(3):285-303.

 

Afset JE, Anderssen E, Bruant G, Harel J, Wieler L, Bergh K. Phylogenetic backgrounds and virulence profiles of atypical enteropathogenic Escherichia coli strains from a case-control study using multilocus sequence typing and DNA microarray analysis. J Clin Microbiol.; 2008 Jul. 46(7):2280-90.

 

 

Eide IP, Isaksen CV, Salvesen KA, Langaas M, Schønberg SA, Austgulen R. Decidual expression and maternal serum levels of heme oxygenase 1 are increased in pre-eclampsia. Acta Obstet Gynecol Scand. 2008 87(3):272-9.

 

Nørsett KG, Laegreid A, Kusnierczyk W, Langaas M, Ylving S, Fossmark R, Myhre S, Falkmer S, Waldum HL, Sandvik AK. Changes in gene expression of gastric mucosa during therapeutic acid inhibition. Eur J Gastroenterol Hepatol. 2008 Jul. 20(7):613-23.

 

Anja Bye, Mette Langaas, Morten A. Høydal, Ole Johan Kemi, Garrett Heinrich, Lauren G. Koch, Steven L. Britton, Sonia M. Najja, Øyvind Ellingsen and Ulrik Wisløff. Aerobic capacity-dependent differences in cardiac gene expression. Physiol Genomics. 2008 Mar. 14;33(1):100-9.

 

Pål A Olsvik, Kai K Lie, Eva Mykkeltvedt, Ole B Samuelsen, Kjell Petersen, Anne-Kristin Stavrum and Bjørn T Lunestad. “Pharmacokinetics and transcriptional effects of the anti-salmon lice drug emamectin benzoate in Atlantic salmon (Salmo salar L.)”. BMC Pharmacology 2008 8:16

 

Caroline Hild Jakobsen, Gro Leite Størvold , Hilde Bremseth , Turid Follestad, Kristin Sand, Merete Mack, Karina Standahl Olsen, Anne Gøril Lundemo, Jens Gustav Iversen, Hans Einar Krokan and Svanhild Arentz Schønberg. “DHA induces ER stress and growth arrest in human colon cancer cells: associations with cholesterol and calcium homeostasis“. Journal of Lipid Research 2008 Volume 49.

 

Christina Sæten Fjeldbo, Kristine Misund, Clara-Cecilie Günther, Mette Langaas, Tonje Strømmen Steigedal, Liv Thommesen, Astrid Lægreid and Torunn Bruland. “Functional studies on transfected cell microarray analysed by linear regression modeling” Nucleic Acids Research 2008 Sept 1–15

 

Rye, M.B., Færgestad, Martens, H., Wold, J.P. and Alsberg, B.K. "An improved pixel-based approach for analysing images in two-dimensional gel electrophoresis." Electrophoresis. 2008 Volume 29 Issue 6, No. 6, Pages 1382–1393.

 

Rye, M.B., Færgestad, and Alsberg, B.K. "A new method for assigning common spot boundaries for multiple gels in two-dimensional gel electrophoresis." Electrophoresis. 2008 Volume 29, Issue 6: No. 6 March 2008, Pages:1359-1368.

 

Rye, M.B., and Alsberg, B.K. "A multivariate spot filtering model for two-dimensional gel electrophoresis." Electrophoresis. Volume 29, Issue 6, Date: No. 6 March 2008, Pages: 1369-1381.

 

Juel IS, Solligård E, Tvedt KE, Skogvoll E, Jynge P, Beisvag V, Erlandsen SE, Sandvik AK, Aadahl P, Grønbech JE. Post-ischaemic restituted intestinal mucosa is more resistant to further ischaemia than normal mucosa in the pig. Scand J Clin Lab Invest. 2008;68(2):106-16.

 

 

2007

 

Kusnierczyk A, Winge P, Midelfart H, Armbruster WS, Rossiter JT, Bones AM. Transcriptional responses of Arabidopsis thaliana ecotypes with different glucosinolate profiles after attack by polyphagous Myzus persicae and oligophagous Brevicoryne brassicae. J Exp Bot. 2007;58(10):2537-2552.

 

Einset J, Nielsen E, Conolly EL, Bones AM, Sparstad T, Winge P, Zhu JK. Membrane-trafficking RabA4c involved in the effect of glycine betaine on recovery from chilling stress in Arabidopsis. Physiologia Plantarum, 2007; 130(4):511-518.

 

Einset J, Winge P and Bones AM. ROS Signaling Pathways in Chilling Stress. Plant Signaling & Behavior 2:5, 365-367, September/October 2007.

 

Irina P. Eide, Christina V. Isaksen, Kjell Å. Salvesen, Mette Langaas, Clara-Cecilie Günther, Ann-Charlotte Iversen and Rigmor Austgulen. “Fetal growth restriction is associated with reduced FasL expression by decidual cells”. Journal of Reproductive Immunology, Volume 74, Issues 1-2, June 2007.

 

Steigedal TS, Bruland T, Misund K, Thommesen L, Laegreid A. “Inducible cAMP early repressor suppresses gastrin-mediated activation of cyclin D1 and c-fos gene expression”. Am J Physiol Gastrointest Liver Physiol. 2007 Apr;292(4):G1062-9. Epub 2006 Dec 21.

 

Osmundsen H, Landin MA, From SH, Kolltveit KM, Risnes S. “Changes in gene-expression during development of the murine molar tooth germ”. Arch Oral Biol. 2007;52:803-13.

 

Gidskehaug L, Anderssen E, Flatberg, A. and Alsberg BK "A framework for significance analysis of gene expression data using dimension reduction methods". BMC Bioinformatics. 2007 Sep 18;8:346.

 

Færgestad, E.M., Rye, M.B., Walczak, B., Gidskehaug, L., Grove, H., Jia, X., Hollung, K., Indahl, U.G., Westad, F., van der Berg, F. and Martens H. "Analysing two dimensional electrophoresis gel images on the level of pixels; a novel approach for analysing the proteome pattern." Proteomics. 2007 Oct;7(19):3450-61.

 

Bruland T, Anderssen E, Doseth B, Bergum H, Beisvag V, Laegreid A. “Optimization of cDNA microarrays procedures using criteria that do not rely on external standards”.

BMC Genomics. 2007 Oct 18;8(1):377

 

Gidskehaug L, Anderssen E, Flatberg A, Alsberg BK. “A framework for significance analysis of gene expression data using dimension reduction methods”. BMC Bioinformatics. 2007 Sep 18;8(1):346

 

Juel IS, Solligård E, Tvedt KE, Skogvoll E, Jynge P, Beisvag V, Erlandsen SE, Sandvik AK, Aadahl P, Grønbech JE. “Post-ischaemic restituted intestinal mucosa is more resistant to further ischaemia than normal mucosa in the pig”.

Scand J Clin Lab Invest. 2007 Sep 12;1-17

 

Erlandsen, S. E., Fykse, V., Waldum, H. L. and Sandvik, A. K., “Octreotide induces apoptosis in the oxyntic mucosa”, Mol Cell Endocrinol, 2007, 264:188-196.

 

 

2006

 

Beisvag, V., Junge, F. K., Bergum, H., Jolsum, L., Lydersen, S., Gunther, C. C., Ramampiaro, H., et al., “GeneTools - application for functional annotation and statistical hypothesis testing”, BMC Bioinformatics, 2006, 7:470.

 

Afset JE, Bruant G, Brousseau R, Harel J, Anderssen E, Bevanger L, Bergh K. “Identification of virulence genes linked with diarrhea due to atypical enteropathogenic Escherichia coli by DNA microarray analysis and PCR”. J Clin Microbiol. 2006 Oct;44(10):3703-11.

 

Murvoll KM, Skaare JU, Moe B, Anderssen E, Jenssen BM. “Spatial trends and associated biological responses of organochlorines and brominated flame retardants in hatchlings of north Atlantic kittiwakes (Rissa tridactyla)”.Environ Toxicol Chem. 2006 Jun;25(6):1648-56.

 

Beisvag, V., Lehre, P. K., Midelfart, H., Aass, H., Geiran, O., Sandvik, A. K., Laegreid, A., “Aetiology-specific patterns in end-stage heart failure patients identified by functional annotation and classification of microarray data”, Eur J Heart Fail, 2006, 8(4):381-389.

 

Sandvik, A. K., Alsberg, B. K., Norsett, K. G., Yadetie, F., Waldum, H. L. and Laegreid, A., “Gene expression analysis and clinical diagnosis”, Clin Chim Acta, 2006, 363(1-2):157-164.

 

Gidskehaug L, Anderssen E, Alsberg B.K. "Cross model validated feature selection based on gene clusters" Chemometrics and intelligent laboratory systems 84 (1-2): 172-176, 2006

 

Myhre S, Tveit H, Mollestad T, Laegreid A. “Additional gene ontology structure for improved biological reasoning”. Bioinformatics. 2006 Aug 15;22(16):2020-7.

 

 

2005

 

Thommesen, L; Sæten C, Steigedal TS; Bruland T. 2005. Bruk av si RNA og RNAi cellearray i studier av molekylære mekanismer i mage-tarmsystemet. NBS-nytt Nr. 3/2005, side 6-11

 

Andersen S, Ericsson M, Dai HY, Pena-Diaz J, Slupphaug G, Nilsen H, Aarset H, Krokan HE. Monoclonal B-cell hyperplasia and leukocyte imbalance precede development of B-cell malignancies in uracil-DNA glycosylase deficient mice. DNA Repair (Mast). 2005 Dec 8;4(12):1432-41.

 

Kristin G. Nørsett, Astrid Lægreid, Mette Langaas, Sara Worlund, Reidar Fossmark, Helge L. Waldum, Arne K Sandvik. Molecular characterisation of rat gastric mucosal response to potent acid inhibition. Physiol Genomic, 22:24-32, 2005.

 

 

2004

 

Fekadu Yadetie, Arne K Sandvik, Hallgeir Bergum, Kristin Nørsett, Astrid Laegreid. Miniaturized fluorescent RNA dot blot method for rapid quantitation of gene expression. BMC Biotechnol,June 10; 4(12),2004.

 

Flikka K, Yadetie F, Laegreid A, Jonassen I. XHM: a system for detection of potential cross hybridizations in DNA microarrays. BMC Bioinformatics. 2004 Aug 27;5:117.

 

 

2003

 

Kristin G. Nørsett, Astrid Lægreid, Herman Midelfart, Fekadu Yadetie, Sture Falkmer, Jon E. Grønbech, Helge L. Waldum, Jan Komorowski, Arne K. Sandvik. Gene expression based classification of gastric carcinoma. Cancer Lett, Jul 16;210(2):227-237, 2004.

 

Yadetie F, Laegreid A, Bakke I, Kusnierczyk W, Komorowski J, Waldum HL, Sandvik AK. Liver gene expression in rats in response to the peroxisome proliferator-activated receptor-alpha agonist ciprofibrate. Physiol Genomics. 2003 Sep 29;15(1):9-19.

 

Hvidsten TR, Laegreid A, Komorowski J. Learning rule-based models of biological process from gene expression time profiles using gene ontology. Bioinformatics. 2003 Jun 12;19(9):1116-23.

 

Alsberg B.K., Kirkhus L., Hagen R., Knudsen O., Tangstad T., Anderssen, E. "Zherlock: An open source data analysis software" SAR and QSAR in environmental research 14 (5-6): 349-360 OCT-DEC 2003

 

 

2002

 

Herman Midelfart, Jan Komorowski, Kristin G. Nørsett, Fekadu Yadetie, Arne K. Sandvik, Astrid Lægreid. Learning Rough Set Classifiers from Gene Expressions and Clinical Data. Fundamenta Informaticae, 53(2): 55-183, 2002.

 

 

2001

 

Arne K. Sandvik, Ole Støren, Kristin Nørsett, Astrid Lægreid, Anne Lise Børresen-Dale, Ola Myklebost. Måling av genaktivitet med DNA-mikromatriser Tidsskr Nor Lægeforen, 121: 1225-8, 2001.

 

Hvidsten TR, Komorowski J, Sandvik AK, Laegreid A. Predicting gene function from gene expressions and ontologies. Pac Symp Biocomput. 2001; 299-310.

 

Jenssen TK, Laegreid A, Komorowski J, Hovig E.  A literature network of human genes for high-throughput analysis of gene expression. Nat Genet. 2001 May;28(1):21-8.

 

Komorowski J, Hvidsten TR, Jenssen TK, Tjeldvoll D, Hovig E, Laegreid A, Sandvik AK. New knowledge derived from measurement of gene expression with the DNA microarray method. Tidsskr Nor Laegeforen. 2001 Apr 20;121(10):1229-32.

 

 

2000

 

Astrid Lægreid, Jan Komorowski, Arne K Sandvik, Eivind Hovig, Anne Forus, Birgitte Smith-Sørensen, Vidar Beisvåg, Bjørn Kristiansen, Kristin Nørsett, Vigdis Nygaard, Ole Støren, Ola Myklebost. DNA-mikroarray – vindu mot tusentals gen. NBS-nytt, 1:14-20, 2000.

Updated Fri, 27 Oct 2017 12:53:32 +0200

Visiting address

Genomics Core Facility
Department of Clinical and Molecular Medicine
Laboratoriesenteret 3. etg. East
Erling Skjalgssonsgt. 1
N-7489 Trondheim
Norway

Postal address

Genomics Core Facility
Department of Clinical and Molecular Medicine
Medisinsk teknisk forskningssenter
Olav Kyrres gt. 9
N-7489 Trondheim
Norway