Kathrine Røe Redalen

Associate Professor

Department of Physics Faculty of Natural Sciences

kathrine.redalen@ntnu.no +47 73413103 +47 92437646

Realfagbygget, D4-164, Gløshaugen, Høgskoleringen 5

I am Associate Professor at Department of Physics, NTNU, from 2017. I obtained my PhD from the University of Oslo in 2012 with research carried out at the Norwegian Radium Hospital.

Research

Research activities include functional cancer imaging (positron emission tomography (PET) and magnetic resonance imaging (MRI)), where we develop new acquisiton methods and image analysis approaches aimed at achieving a more precise cancer diagnosis, to retrieve predictive and prognostic information on treatment outcome and survival as well as improved evaluation of treatment efficacy during treatment. Further, we are using functional imaging to map the radiation sensitivity in individual tumours by utilising different approaches to quantitatively assess tumour oxygenation and vascular function, which are two important characteristics in the tumour microenvironment that affect both therapeutic response and disease outcome. Our imaging research is centred around applications in the field of radiotherapy, where we aim to improve the use of advanced imaging in radiation dose delivery and integrate PET and MRI information in modelling of both tumour response and normal tissue toxicity following radiation. We also have ongoing activity within functional MRI-based tumour segmentation approaches using machine learning.

Research projects

CURIE - Cancer imaging by fUnctional magnetic resonance for Radiotherapy Individualisation and Evaluation, funded by the Norwegian Cancer Society, 2019 - 2023
Improved diagnostics and treatment through a state-of-the-art multi-center nuclear medicine approach: Applications in cancer and dementia (180N - Norwegian Nuclear Medicine Consortium), funded by Trond Mohn Foundation, Central Norway Regional Health Authority, St. Olavs hospital and NTNU, 2019 - 2024
Improved strategies for radiotherapy of prostate cancer utilizing proton therapy and advanced imaging modalities, funded by Central Norway Regional Health Authority, 2018 - 2023
Development of Cu-64 radiopharmaceuticals for positron emission tomography (PET) and treatment of hypoxic, aggressive cancer, funded by Central Norway Regional Health Authority, 2019 - 2022

Research group members:

Associate Professor II Signe Danielsen
Associate Professor II Anne Beate L. Marthinsen
Postdoc René Winter
PhD candidate Franziska H. Knuth
PhD candidate Kajsa M. L. Fridström
PhD candidate Tengzhi Liu
PhD candidate Guillermo Garrido Hernández
MSc student Eline Furu Skjelbred
MSc student Frida Marie Ihle Julbø
MSc student Kaja Slåtsve Øvrelid
MSc student Aase Mellingen Langan

Current teaching activities

Fall semester: TFY4225 - Radiation and Nuclear Physics

Spring semester: TFY4315 - Biophysics of Ionizing Radiation

Other

I am member of the Young Academy of Norway and the Young Committee/Physics Committee of the European Society for Radiotherapy and Oncology.

Scientific, academic and artistic work

Displaying a selection of activities. See all publications in the database

Journal publications

Abrahamsson, Hanna Josefine; Porojnicu, Alina Carmen; Lindstrøm, Jonas Christoffer; Dueland, Svein; Flatmark, Kjersti; Hole, Knut Håkon; Seierstad, Therese; Moan, Johan Emilian; Redalen, Kathrine; Meltzer, Sebastian; Ree, Anne Hansen. (2019) High level of circulating vitamin D during neoadjuvant therapy may lower risk of metastatic progression in high-risk rectal cancer. BMC Cancer. vol. 19 (1).
Bains, Simer Jit; Abrahamsson, Hanna Josefine; Flatmark, Kjersti; Dueland, Svein; Hole, Knut Håkon; Seierstad, Therese; Redalen, Kathrine; Meltzer, Sebastian; Ree, Anne Hansen. (2019) Immunogenic cell death by neoadjuvant oxaliplatin and radiation protects against metastatic failure in high-risk rectal cancer. Cancer Immunology and Immunotherapy.
Bakke, Kine Mari; Grøvik, Endre; Meltzer, Sebastian; Negård, Anne; Holmedal, Stein Harald; Mikalsen, Lars Tore G; Lyckander, Lars Gustav; Ree, Anne Hansen; Gjesdal, Kjell-Inge; Redalen, Kathrine; Bjørnerud, Atle. (2019) Comparison of Intravoxel incoherent motion imaging and multiecho dynamic contrast-based MRI in rectal cancer. Journal of Magnetic Resonance Imaging. vol. 50 (4).
Bjørnetrø, Tonje; Redalen, Kathrine; Meltzer, Sebastian; Thusyanthan, Nirujah Sivarajah; Samiappan, Rampradeep; Jegershöld, Caroline; Handeland, Karianne Risberg; Ree, Anne Hansen. (2019) An experimental strategy unveiling exosomal microRNAs 486-5p, 181a-5p and 30d-5p from hypoxic tumour cells as circulating indicators of high-risk rectal cancer. Journal of Extracellular Vesicles. vol. 8 (1).
Goa, Pål Erik; Marthinsen, Anne Beate Langeland; Redalen, Kathrine; Danielsen, Signe; Wanderås, Anne Dybdahl. (2019) Hva er fordelene med protonterapi sammenlignet med stråleterapi med fotoner, og hvorfor?. HMT - Helsetjenesten Medisinsk Teknikk : helse, medisin, teknikk. vol. 5.
Meltzer, Sebastian; Bakke, Kine Mari; Rød, Karina Lund; Negård, Anne; Flatmark, Kjersti; Solbakken, Arne Mide; Kristensen, Annette Torgunrud; Fuglestad, Anniken Jørlo; Kersten, Christian; Dueland, Svein; Seierstad, Therese; Hole, Knut Håkon; Lyckander, Lars Gustav; Larsen, Finn Ole; Schou, Jakob Vasehus; Brown, Dawn; Abrahamsson, Hanna Josefine; Redalen, Kathrine; Ree, Anne Hansen. (2019) Sex-related differences in primary metastatic site in rectal cancer; associated with hemodynamic factors?. Clinical and Translational Radiation Oncology. vol. 21.
Meltzer, Sebastian; Bjørnetrø, Tonje; Lyckander, Lars Gustav; Flatmark, Kjersti; Dueland, Svein; Samiappan, Rampradeep; Johansen, Christin; Kalanxhi, Ert; Ree, Anne Hansen; Redalen, Kathrine. (2019) Circulating Exosomal miR-141-3p and miR-375 in Metastatic Progression of Rectal Cancer. Translational Oncology. vol. 12 (8).
Bibault, Jean-Emmanuel; Franco, Pierfrancesco; Borst, Gerben R.; van Elmpt, Wouter; Thorwarth, Daniela; Schmid, Maximilian P; Rouschop, Kasper M; Spalek, Mateusz; Mullaney, Laura; Redalen, Kathrine; Dubois, Ludwig; Verfaille, Christine; Eriksen, Jesper Grau. (2018) Learning radiation oncology in Europe: Results of the ESTRO multidisciplinary survey. Clinical and Translational Radiation Oncology. vol. 9.
Bousquet, Paula; Meltzer, Sebastian; Sønstevold, Linda; Esbensen, Qin Ying; Dueland, Svein; Flatmark, Kjersti; Sitter, Beathe; Bathen, Tone Frost; Seierstad, Therese; Redalen, Kathrine; Eide, Lars; Ree, Anne Hansen. (2018) Markers of mitochondrial metabolism in tumor hypoxia, systemic inflammation, and adverse outcome of rectal cancer. Translational Oncology. vol. 12 (1).
Gopinathan, Unni; Redalen, Kathrine; Siebke, Anne-Marie; Kierulf, Peter; Brandtzæg, Petter; Ree, Anne Hansen; Berg, Jens Petter; Øvstebø, Reidun. (2018) Large-scale reduction of tyrosine kinase activities in human monocytes stimulated in vitro with N. meningitidis. PLOS ONE. vol. 13 (1).
Kalanxhi, Ert; Meltzer, Sebastian; Schou, Jakob Vasehus; Larsen, Finn Ole; Dueland, Svein; Flatmark, Kjersti; Jensen, Benny Vittrup; Hole, Knut Håkon; Seierstad, Therese; Redalen, Kathrine; Nielsen, Dorte Lisbet; Ree, Anne Hansen. (2018) Systemic immune response induced by oxaliplatin-based neoadjuvant therapy favours survival without metastatic progression in high-risk rectal cancer. British Journal of Cancer. vol. 118 (10).
Bakke, Kine Mari; Hole, Knut Håkon; Dueland, Svein; Kotanska-Grøholt, Krystyna; Flatmark, Kjersti; Ree, Anne Hansen; Seierstad, Therese; Redalen, Kathrine Røe. (2017) Diffusion-weighted magnetic resonance imaging of rectal cancer: tumour volume and perfusion fraction predict chemoradiotherapy response and survival. Acta Oncologica. vol. 56 (6).
Bjørnetrø, Tonje; Risberg, Karianne; Meltzer, Sebastian; Samiappan, Rampradeep; Lyckander, Lars Gustav; Jegerschöld, Caroline; Sønstevold, Linda; Thusyanthan, Nirujah; Redalen, Kathrine Røe; Ree, Anne Hansen. (2017) Low release of exosomal miR-663a from hypoxic tumor cells and poor tumor response to neoadjuvant radiotherapy in rectal cancer patients. Cancer Research. vol. 77.
Bousquet, Paula; Meltzer, Sebastian; Sønstevold, Linda; Esbensen, Qin Ying; Lyckander, Lars Gustav; Dueland, Svein; Flatmark, Kjersti; Redalen, Kathrine Røe; Eide, Lars; Ree, Anne Hansen. (2017) Reactive oxygen species (ROS) and mitochondrial DNA (mtDNA) damage in tumor hypoxia, poor radiotherapy response, and metastatic progression of rectal cancer. Cancer Research. vol. 77.
Fleten, Karianne Giller; Bakke, Kine Mari; Mælandsmo, Gunhild; Abildgaard, Andreas; Redalen, Kathrine Røe; Flatmark, Kjersti. (2017) Use of non-invasive imaging to monitor response to aflibercept treatment in murine models of colorectal cancer liver metastases. Clinical and Experimental Metastasis. vol. 34 (1).
Grøvik, Endre; Redalen, Kathrine Røe; Storås, Tryggve; Negard, Anne; Holmedal, Stein Harald; Ree, Anne Hansen; Meltzer, Sebastian; Bjørnerud, Atle; Gjesdal, Kjell-Inge. (2017) Dynamic multi-echo DCE- and DSC-MRI in rectal cancer: Low primary tumor Ktrans and ΔR2* peak are significantly associated with lymph node metastasis. Journal of Magnetic Resonance Imaging. vol. 46 (1).
Kalanxhi, Ert; Risberg, Karianne; Barua, Imon Shoumitra; Dueland, Svein; Waagene, Stein; Andersen, Solveig Norheim; Pettersen, Solveig; Lindvall, Jessica Margareta; Redalen, Kathrine Røe; Flatmark, Kjersti; Ree, Anne Hansen. (2017) Induction of Apoptosis in Intestinal Toxicity to a Histone Deacetylase Inhibitor in a Phase I Study with Pelvic Radiotherapy. Cancer research and treatment : official journal of Korean Cancer Association. vol. 49 (2).
Redalen, Kathrine; Levin, Nina; Sæther, Oddbjørn; Goa, Pål Erik. (2017) MR i strålebehandling – muligheter og utfordringer. HMT - Helsetjenesten Medisinsk Teknikk : helse, medisin, teknikk. vol. 5.
Flatmark, Kjersti; Sælen, Marie Grøn; Hole, Knut Håkon; Abrahamsen, Torveig Weum; Fleten, Karianne Giller; Hektoen, Helga; Redalen, Kathrine Røe; Seierstad, Therese; Dueland, Svein; Ree, Anne Hansen. (2016) Individual tumor volume responses to short-course oxaliplatin containing induction chemotherapy in locally advanced rectal cancer – Targeting the tumor for radiation sensitivity?. Radiotherapy and Oncology. vol. 119 (3).
Meltzer, Sebastian; Kalanxhi, Ert; Hektoen, Helga; Dueland, Svein; Flatmark, Kjersti; Redalen, Kathrine Røe; Ree, Anne Hansen. (2016) Systemic release of osteoprotegerin during oxaliplatin-containing induction chemotherapy and favorable systemic outcome of sequential radiotherapy in rectal cancer. OncoTarget. vol. 7 (23).
Meunier, Armelle; Flores, Angela Nilda; McDermott, Niamh; Rivera-Figueroa, Karla; Perry, Antoinette; Lynch, Thomas; Redalen, Kathrine Røe; Marignol, Laure. (2016) Hypoxia regulates Notch-3 mRNA and receptor activation in prostate cancer cells. Heliyon. vol. 2 (5).
Redalen, Kathrine Røe; Sitter, Beathe; Bathen, Tone Frost; Kotanska-Grøholt, Krystyna; Hole, Knut Håkon; Dueland, Svein; Flatmark, Kjersti; Ree, Anne Hansen; Seierstad, Therese. (2016) High tumor glycine concentration is an adverse prognostic factor in locally advanced rectal cancer. Radiotherapy and Oncology. vol. 118 (2).
Risberg, Karianne; Redalen, Kathrine Røe; Sønstevold, Linda; Bjørnetrø, Tonje; Sølvernes, Janne; Ree, Anne Hansen. (2016) Pro-survival responses to the dual inhibition of anti-apoptotic Bcl-2 family proteins and mTOR-mediated signaling in hypoxic colorectal carcinoma cells. BMC Cancer. vol. 16:531.
Bornstein, Marius; Negård, Anne; Holmedal, Stein Harald; Borthne, Arne Sigmund; Ree, Anne Hansen; Redalen, Kathrine Røe. (2015) Quantitative diffusion-weighted MRI of rectal cancer is strongly influenced by the choice of b-values. Radiotherapy and Oncology. vol. 115.
Hektoen, Helga; Flatmark, Kjersti; Andersson, Yvonne; Dueland, Svein; Redalen, Kathrine Røe; Ree, Anne Hansen. (2015) Early increase in circulating carbonic anhydrase IX during neoadjuvant treatment predicts favourable outcome in locally advanced rectal cancer. BMC Cancer. vol. 15:543.
Hektoen, Helga; Ree, Anne Hansen; Redalen, Kathrine Røe; Flatmark, Kjersti. (2015) Sulfamate inhibitor S4 influences carbonic anhydrase IX ectodomain shedding in colorectal carcinoma cells. Journal of enzyme inhibition and medicinal chemistry (Print). vol. 31 (5).
Kalanxhi, Ert; Hektoen, Helga; Meltzer, Sebastian; Dueland, Svein; Redalen, Kathrine Røe; Flatmark, Kjersti; Ree, Anne Hansen. (2015) Circulating proteins in response to combined-modality therapy in locally advanced rectal cancer identified by antibody array screening. Cancer Research. vol. 75 (15).
Ree, Anne Hansen; Flatmark, Kjersti; Sælen, Marie Grøn; Folkvord, Sigurd; Dueland, Svein; Geisler, Jürgen; Redalen, Kathrine Røe. (2015) High tumor PI3K signaling in resistance to chemoradiotherapy and metastatic dissemination of locally advanced rectal cancer. Molecular Cancer Therapeutics. vol. 14 (7).
Ree, Anne Hansen; Flatmark, Kjersti; Sælen, Marie Grøn; Folkvord, Sigurd; Dueland, Svein; Geisler, Jürgen; Redalen, Kathrine Røe. (2015) Tumor phosphatidylinositol 3-kinase signaling in therapy resistance and metastatic dissemination of rectal cancer: Opportunities for signaling-adapted therapies. Critical Reviews in Oncology/Hematology. vol. 95 (1).
Ree, Anne Hansen; Redalen, Kathrine Røe. (2015) Personalized radiotherapy: concepts, biomarkers and trial design. British Journal of Radiology. vol. 88:20150009 (1051).
Seierstad, Therese; Hole, Knut Håkon; Grøholt, Krystyna Kotanska; Dueland, Svein; Ree, Anne Hansen; Flatmark, Kjersti; Redalen, Kathrine Røe. (2015) Prediction of response to neoadjuvant chemotherapy followed by chemoradiotherapy in rectal cancer by MRI volumetry. Radiotherapy and Oncology. vol. 115.
Seierstad, Therese; Hole, Knut Håkon; Kotanska-Grøholt, Krystyna; Dueland, Svein; Ree, Anne Hansen; Flatmark, Kjersti; Redalen, Kathrine Røe. (2015) MRI volumetry for prediction of tumour response to neoadjuvant chemotherapy followed by chemoradiotherapy in locally advanced rectal cancer. British Journal of Radiology. vol. 88:20150097 (1051).
Hektoen, Helga; Flatmark, Kjersti; Landsverk, Kirsti; Sælen, Marie Grøn; Redalen, Kathrine Røe; Ree, Anne Hansen. (2014) On the role of experimental microenvironmental conditions in targeted inhibition of the pH-regulating carbonic anhydrase IX in colorectal carcinoma cells. Cancer Research. vol. 74.
Kalanxhi, Ert; Risberg, Karianne; Dueland, Svein; Redalen, Kathrine Røe; Flatmark, Kjersti; Ree, Anne Hansen. (2014) Molecular mechanisms of targeted drug toxicities in a clinical combined-modality radiotherapy study. Radiotherapy and Oncology. vol. 111.
Ree, Anne Hansen; Sælen, Marie Grøn; Kalanxhi, Ert; Østensen, Ingrid H.G; Schee, Kristina; Redalen, Kathrine Røe; Abrahamsen, Torveig Weum; Dueland, Svein; Flatmark, Kjersti. (2014) The Pelvic Radiation and Vorinostat (PRAVO) phase 1 study identifying MYC repression as biomarker of histone deacetylase inhibitor activity. Molecular Cancer Therapeutics. vol. 12.
Ree, Anne Hansen; Sælen, Marie Grøn; Kalanxhi, Erta; Østensen, Ingrid Helene Garmann; Schee, Kristina; Røe, Kathrine; Abrahamsen, Torveig Weum; Dueland, Svein; Flatmark, Kjersti. (2014) Biomarkers of histone deacetylase inhibitor activity in a phase 1 combined-modality study with radiotherapy. PLOS ONE. vol. 9 (2).
Risberg, Karianne; Redalen, Kathrine Røe; Ree, Anne Hansen. (2014) Kinase activity in vemurafenib-sensitive and resistant BRAF-mutant melanoma cells. Molecular Cancer Therapeutics. vol. 12.
Røe, Kathrine. (2014) Nye MR-teknikker for evaluering og prediksjon av respons på neoadjuvant behandling ved rektumcancer. Bestpractice Onkologi/Hematologi. vol. 16.
Heyerdahl, Helen; Røe, Kathrine; Brevik, Ellen Mengshoel; Dahle, Jostein. (2013) Modifications in dynamic contrast-enhanced magnetic resonance imaging parameters after alpha-particle-emitting Th-227-trastuzumab therapy of HER2-expressing ovarian cancer xenografts. International Journal of Radiation Oncology, Biology, Physics. vol. 87 (1).
Ragnum, Harald Bull; Røe, Kathrine; Holm, Ruth; Vlatkovic, Ljiljana; Nesland, Jahn M; Aarnes, Eva-Katrine; Ree, Anne Hansen; Flatmark, Kjersti; Seierstad, Therese; Lilleby, Wolfgang; Lyng, Heidi. (2013) Hypoxia-independent downregulation of hypoxia-inducible factor 1 targets by androgen deprivation therapy in prostate cancer. International Journal of Radiation Oncology, Biology, Physics. vol. 87 (4).
Røe, Kathrine; Bratland, Åse; Vlatkovic, Ljiljana; Ragnum, Harald Bull; Sælen, Marie Grøn; Olsen, Dag Rune; Marignol, Laure; Ree, Anne Hansen. (2013) Hypoxic tumor kinase signaling mediated by STAT5A in development of castration-resistant prostate cancer. PLOS ONE. vol. 8 (5).
Tahiri, Andliena; Røe, Kathrine; Ree, Anne Hansen; de Wijn, Rik; Risberg, Karianne; Busch, Christer; Lønning, Per Eystein; Kristensen, Vessela N.; Geisler, Jürgen. (2013) Differential inhibition of ex-vivo tumor kinase activity by vemurafenib in BRAF(V600E) and BRAF wild-type metastatic malignant melanoma. PLOS ONE. vol. 8 (8).
Ragnum, Harald Bull; Seierstad, Therese; Redalen, Kathrine Røe; Nesland, Jahn M; Holm, Ruth; Lilleby, Wolfgang; Lyng, Heidi. (2012) ANDROGEN DEPRIVATION THERAPY PRIOR TO IRRADIATION OF PROSTATE CANCER: EXPRESSION OF HYPOXIA-INDUCED PROTEINS AND CHANGES IN DIFFUSION WEIGHTED MRI PARAMETERS. Radiotherapy and Oncology. vol. 102.
Redalen, Kathrine Røe; Mikalsen, Lars Tore G; van der Kogel, Albert; Bussink, Johan; Lyng, Heidi; Ree, Anne Hansen; Marignol, Laure; Olsen, Dag Rune. (2012) DCEMRI IN ASSESSMENT OF TUMOR NEOVASCULARIZATION AFTER ANDROGEN-DEPRIVATION IN EXPERIMENTAL PROSTATE CANCER: CORRELATION TO QUANTITATIVE IMMUNOHISTOCHEMISTRY. Radiotherapy and Oncology. vol. 102.
Røe, Kathrine; Mikalsen, Lars Tore G; van der Kogel, Albert; Bussink, Johan; Lyng, Heidi; Ree, Anne Hansen; Marignol, Laure; Olsen, Dag Rune. (2012) Vascular responses to radiotherapy and androgen-deprivation therapy in experimental prostate cancer. Radiation Oncology. vol. 7.
Hagtvet, Eirik; Røe, Kathrine; Olsen, Dag Rune. (2011) Liposomal doxorubicin improves radiotherapy response in hypoxic prostate cancer xenografts. Radiation Oncology. vol. 6.
Redalen, Kathrine Røe. (2011) Protein kinase activity and therapy response. European Journal of Cancer.
Revheim, Mona Elisabeth; Røe, Kathrine; Bruland, Øyvind; Bach-Gansmo, Tore; Skretting, Arne; Seierstad, Therese. (2011) Monitoring the Effect of Targeted Therapies in a Gastrointestinal Stromal Tumor Xenograft Using a Clinical PET/CT. Molecular Imaging and Biology. vol. 13 (6).
Røe, Kathrine; Kakar, Manish; Seierstad, Therese; Ree, Anne Hansen; Olsen, Dag Rune. (2011) Early prediction of response to radiotherapy and androgen-deprivation therapy in prostate cancer by repeated functional MRI: a preclinical study. Radiation Oncology. vol. 6.
Lilleby, Wolfgang; Solca, Flavio; Røe, Kathrine. (2010) Radiotherapy and inhibition of the EGF family as treatment strategies for prostate cancer: combining theragnostics with theragates. Oncology Reviews. vol. 5 (2).
Revheim, Mona Elisabeth; Røe, Kathrine; Bruland, Øyvind; Bach-Gansmo, Tore; Skretting, Arne; Seierstad, Therese. (2010) Monitoring the Effect of Targeted Therapies in a Gastrointestinal Stromal Tumor Xenograft Using a Clinical PET/CT. Molecular Imaging and Biology.
Røe, Kathrine; Aleksandersen, Thomas Bandur; Kristian, Alexandr; Nilsen, Line; Seierstad, Therese; Qu, Hong; Ree, Anne Hansen; Olsen, Dag Rune; Malinen, Eirik. (2010) Preclinical dynamic F-18-FDG PET - tumor characterization and radiotherapy response assessment by kinetic compartment analysis. Acta Oncologica. vol. 49 (7).
Røe, Kathrine; Olsen, Dag Rune; Seierstad, Therese; Ree, Anne Hansen; Kakar, Manish. (2010) Prediction of response to cancer therapy from functional magnetic resonance image parameters - an artificial neural network approach. European Journal of Cancer. vol. 8 (5).
Røe, Kathrine; Seierstad, Therese; Kristian, Alexandr; Mikalsen, Lars Tore G; Mælandsmo, Gunhild; van der Kogel, Albert; Ree, Anne Hansen; Olsen, Dag Rune. (2010) Longitudinal magnetic resonance imaging-based assessment of vascular changes and radiation response in androgen-sensitive prostate carcinoma xenografts under androgen-exposed and androgen-deprived conditions. Neoplasia. vol. 12 (10).
Seierstad, Therese; Bruland, Øyvind Sverre; Røe, Kathrine; Bjerkehagen, Bodil; Berner, Jeanne-Marie; Revheim, Mona-Elisabeth; Bach-Gansmo, Tore. (2009) Establishment and Characterization of a Human Gastrointestinal Stromal Tumour (GIST) Xenograft in Athymic Nude Mice. Anticancer Research. vol. 29 (11).
Kakar, Manish; Seierstad, Therese; Røe, Kathrine; Olsen, Dag Rune. (2009) Artificial neural networks for prediction of response to chemoradiation in HT29 xenografts. International Journal of Radiation Oncology, Biology, Physics. vol. 75 (2).
Kakar, Manish; Therese, Seierstad; Røe, Kathrine; Olsen, Dag Rune. (2009) Artificial neural networks for prediction of response to chemoradiation in ht29 xenografts. International Journal of Radiation Oncology, Biology, Physics. vol. 75 (2).
Røe, Kathrine; Muren, Ludvig; Rørvik, Jarle; Olsen, Dag Rune; Dahl, Olav; Bakke, August; Malinen, Eirik. (2008) Dynamic contrast enhanced magnetic resonance imaging of bladder cancer and implications for biological image-adapted radiotherapy. Acta Oncologica. vol. 47 (7).
Folkvord, Sigurd; Flatmark, Kjersti; Seierstad, Therese; Røe, Kathrine; Rasmussen, Heidi; Ree, Anne Hansen. (2008) Inhibitory effects of oxaliplatin in experimental radiation trestment of colorectal carcinoma : does oxiliplatin improve 5-fluorouracil-dependent radiosensivity?. Radiotherapy and Oncology. vol. 86.
Seierstad, Therese; Redalen, Kathrine Røe; Sitter, Beathe; Halgunset, Jostein; Flatmark, Kjersti; Ree, Anne Hansen; Olsen, Dag Rune; Gribbestad, Ingrid S; Bathen, Tone Frost. (2008) Principal component analysis for the comparison of metabolic profiles from human rectal cancer biopsies and colorectal xenografts using high–resolution magic angle spinning 1H magnetic resonance spectroscopy. Molecular Cancer. vol. 25 (7).
Olsen, Dag Rune; Seierstad, Therese; Folkvord, Sigurd; Røe, Kathrine; Flatmark, Kjersti; Ree, Anne Hansen. (2007) Treatment response following combined capecitabine, oxaliplatin and radiation therapy monitored by diffusion weighted magnetic resonance imaging (DW-MRI) in a xenograft model. European Journal of Cancer Supplements. vol. 5 (4).
Seierstad, Therese; Folkvord, Sigurd; Røe, Kathrine; Flatmark, Kjersti; Skretting, Arne; Olsen, Dag Rune. (2007) Early changes in apparent diffusion coefficient predict the quantitative antitumoral activity of capecitabene, oxaliplatin, and irradiation in HT29 xenografts in athymic nude mice. Neoplasia. vol. 9 (5).
Seierstad, Therese; Røe, Kathrine; Høvik, B.. (2007) Construction of a modified capacitive overlap MR coil for imaging of small animals and objects in a clinical whole-body scanner. Physics in Medicine and Biology. vol. 52.
Seierstad, Therese; Røe, Kathrine; Olsen, Dag Rune. (2007) Noninvasive monitoring of radiation-induced treatment respons using proton magnetic resonance spectroscopy and diffusion-weighted magnetic resonance imaging in a colorectal tumor model. Radiotherapy and Oncology. vol. 85.

Others

Frøyen, Elin Agathe; Lyckander, Lars Gustav; Grandal, Ole Jacob; Lunder, Aida Kapic; Meltzer, Sebastian; Redalen, Kathrine; Ree, Anne Hansen; Negård, Anne. (2019) MRI of Extramural Venous Invasion in rectal cancer: assessment of the interobserver agreement and comparison with histopathology stained with hematoxylin/eosin and elastin. European Congress for Gastrointestinal and Abdominal Radiology . European Society for Gastroinestinal and Abdominal Radiolog); Roma. 2019-06-04 - 2019-06-08.
Knuth, Franziska; Grøndahl, Aurora Rosvoll; Torheim, Turid Katrine Gjerstad; Negård, Anne; Holmedal, Stein Harald; Bakke, Kine Mari; Meltzer, Sebastian; Futsæther, Cecilia Marie; Redalen, Kathrine. (2019) Automatic tumor delineation in rectal cancer using functional MRI and machine learning. MedFys 2019 . Norsk Forening for Medisinisk Fysikk; Kvitfjell. 2019-02-04 - 2019-02-06.
Knuth, Franziska; Grøndahl, Aurora Rosvoll; Torheim, Turid Katrine Gjerstad; Negård, Anne; Holmedal, Stein Harald; Bakke, Kine Mari; Meltzer, Sebastian; Futsæther, Cecilia Marie; Redalen, Kathrine. (2019) Automatic tumour delineation in rectal cancer using functional MRI and machine learning. ESTRO 38 . European Society for Radiotherapy and Oncology; Milan. 2019-04-26 - 2019-04-30.
Knuth, Franziska; Grøndahl, Aurora Rosvoll; Torheim, Turid Katrine Gjerstad; Negård, Anne; Holmedal, Stein Harald; Bakke, Kine Mari; Meltzer, Sebastian; Futsæther, Cecilia Marie; Redalen, Kathrine. (2019) Functional MR-based automatic tumor segmentation of rectal cancer. BiGART2019 - 18th Acta Oncologica conference ; Aarhus. 2019-05-22 - 2019-05-24.
Meltzer, Sebastian; Bakke, Kine Mari; Lund Rød, Karina; Dueland, Svein; Flatmark, Kjersti; Kristensen, Annette Torgunrud; Larsen, Finn Ole; Schou, Jakob Vasehus; Fuglestad, Anniken Jørlo; Kersten, Christian; Redalen, Kathrine; Ree, Anne Hansen. (2019) Gender disparities in outcome after neoadjuvant chemoradiotherapy for locally advanced rectal cancer are associated with hemodynamic differences. ESTRO 38 . European Society for Radiation Oncology; Milano. 2019-04-26 - 2019-04-30.
Meltzer, Sebastian; Redalen, Kathrine; Dueland, Svein; Kristensen, Annette Torgunrud; Solbakken, Arne Mide; Flatmark, Kjersti; Ree, Anne Hansen. (2019) Circulating angiogenic factors predict metastatic liver progression in rectal cancer patients given curative-intent oxaliplatin-containing neoadjuvant therapy. American Association for Cancer Research Annual Meeting . American Association for Cancer Research; Atlanta, Georgia. 2019-03-29 - 2019-04-03.
Redalen, Kathrine. (2019) Funksjonell MR; verktøy for prediksjon av behandlingseffekt ved rektumcancer. Multidisiplinært onkologisk GI-cancer møte . Amgen og Bayer; Trondheim. 2019-02-07 - 2019-02-08.
Redalen, Kathrine. (2019) Imaging biomarkers. MED3062 – Påvisning og monitorering av sykdom i laboratoriet . Universitetet i Oslo; Akershus universitetssykehus. 2019-01-21 - 2019-02-01.
Redalen, Kathrine. (2019) Kan bedre bildediagnostikk gjøre kreftbehandlingen enda bedre?. Temakafé for kreftpasienter og pårørende . Kreftforeningen; Steinkjer. 2019-09-25 - 2019-09-25.
Redalen, Kathrine. (2019) MRI-based dose-painting of rectal cancer. 34th Conference on Clinical and Experimental Research in Radiation Oncology (CERRO) . ESTRO (European Society for Radiotherapy and Oncology); Le Menuires. 2019-01-19 - 2019-01-26.
Redalen, Kathrine. (2019) Maskinlæring i stråleterapi. Norsk stråleterapimøte . Norsk forening for medisinsk fysikk; Oslo. 2019-09-19 - 2019-09-20.
Redalen, Kathrine. (2019) What characterizes a good relationship between a supervisor and a student?. TEKNA seminar - Academic supervision . TEKNA; Litteraturhuset, Trondheim. 2019-03-07 - 2019-03-07.
Bakke, Kine Mari; Meltzer, Sebastian; Lyckander, Lars Gustav; Holmedal, Stein Harald; Negård, Anne; Gjesdal, Kjell-Inge; Grøvik, Endre; Redalen, Kathrine. (2018) Predicting tumour response to chemoradiotherapy in rectal cancer using dynamic contrast enhanced MRI. European Society for Radiotherapy and Oncology (ESTRO) 37th annual meeting . ESTRO (European Society for Radiotherapy and Oncology); Barcelona. 2018-04-20 - 2018-04-24.
Melles, Woldegabriel A; Meltzer, Sebastian; Bakke, Kine Mari; Storaas H, Tryggve; Holmedal, Stein Harald; Redalen, Kathrine; Negård, Anne. (2018) Comparison of Apparent Diffusion Coefficients from Diffusion-Weighted Imaging of Rectal Cancer at different MR scanners. European Congress of Radiology 2018 . European Society of Radiology; Wien. 2018-02-28 - 2018-03-02.
Redalen, Kathrine. (2018) Baseline dynamic R2* MRI in rectal cancer is associated with chemoradiotherapy outcome. 6th MR in RT symposium ; Utrecht. 2018-06-30 - 2018-07-03.
Redalen, Kathrine. (2018) Biomarker discovery. 2nd ESTRO Physics workshop . ESTRO (European Society for Radiotherapy and Oncology); Malaga. 2018-10-26 - 2018-10-27.
Redalen, Kathrine. (2018) Bruk av MR for utredning og behandling av kreft med spesielt henblikk på colorectal og prostata. Seminar Kreftklinikken, St. Olavs hospital ; 2018-04-05 - 2018-04-05.
Redalen, Kathrine. (2018) MRI in radiotherapy. MRI in radiotherapy . Kreftklinikken, St. Olavs hospital og Inst. for fysikk, NTNU; Trondheim. 2018-12-05 - 2018-12-05.
Redalen, Kathrine. (2018) Motivasjonsforedrag. Fakultet for naturvitenskap sin velkomstdag for jenter . Fakultet for naturvitenskap; Trondheim. 2018-08-12 - 2018-08-12.
Syversen, Ingrid Framås; Bakke, Kine Mari; Grøvik, Endre; Negård, Anne; Holmedal, Stein Harald; Lyckander, Lars Gustav; Gjesdal, Kjell-Inge; Meltzer, Sebastian; Redalen, Kathrine. (2018) Prediction of chemoradiotherapy response in rectal cancer using static and dynamic R2* MRI. European Society for Radiotherapy and Oncology (ESTRO) 37th annual meeting . ESTRO (European Society for Radiotherapy and Oncology); Barcelona. 2018-04-20 - 2018-04-24.
Bakke, Kine Mari; Hole, Knut Håkon; Dueland, Svein; Grøholt, Krystyna Kotanska; Ree, Anne Hansen; Flatmark, Kjersti; Seierstad, Therese; Redalen, Kathrine Røe. (2017) Diffusion-weighted MRI of rectal cancer: baseline tumour perfusion fraction predicts chemoradiotherapy response and survival. International Society for Magnetic Resonance in Medicine 25th Annual Meeting . International Society for Magnetic Resonance in Medicine; Hawaii. 2017-04-22 - 2017-04-27.
Barua, Imon Shoumitra; Ree, Anne Hansen; Sønstevold, Linda; Redalen, Kathrine Røe; Kalanxhi, Ert. (2017) Mechanisms of normal tissue toxicity from SAHA - an HDAC inhibitor and radiosensitizer. ESTRO 36 - Annual Meeting of the European Society for Radiotherapy & Oncology . European Society for Radiotherapy & Oncology; Wien. 2017-05-05 - 2017-05-09.
Grøvik, Endre; Redalen, Kathrine Røe; Storås, Tryggve; Holmedal, Stein Harald; Negard, Anne; Ree, Anne Hansen; Meltzer, Sebastian; Bjørnerud, Atle; Gjesdal, Kjell-Inge. (2017) Improved sensitivity for rectal cancer differentiation by T2*-correction in DCE-MRI. International Society for Magnetic Resonance in Medicine 25th Annual Meeting . International Society for Magnetic Resonance in Medicine; Hawaii. 2017-04-22 - 2017-04-27.
Meltzer, Sebastian; Lyckander, Lars Gustav; Ree, Anne Hansen; Redalen, Kathrine Røe. (2017) Circulating angiogenesis factors predicting poor chemoradiotherapy outcome in rectal cancer. ESTRO 36 - Annual Meeting of the European Society for Radiotherapy & Oncology . European Society for Radiotherapy & Oncology; Wien. 2017-05-05 - 2017-05-09.
Meltzer, Sebastian; Ree, Anne Hansen; Lyckander, Lars Gustav; Redalen, Kathrine Røe. (2017) Circulating exosomal miRNA related to chemoradiotherapy outcome in locally advanced rectal cancer. ESTRO 36 - Annual Meeting of the European Society for Radiotherapy & Oncology . European Society for Radiotherapy & Oncology; Wien. 2017-05-05 - 2017-05-09.
Redalen, Kathrine Røe. (2017) Extracellular vesicles in radiation oncology. ESTRO 36 - Annual Meeting of the European Society for Radiotherapy & Oncology . European Society for Radiotherapy & Oncology; Wien. 2017-05-05 - 2017-05-09.
Redalen, Kathrine Røe. (2017) Functional MRI in metastatic colorectal cancer. Regional Research Network Acredit - Advanced Colorectal Cancer Individualization of Therapies ; 2017-11-02 - 2017-11-03.
Redalen, Kathrine Røe. (2017) Tok sjansen, fikk gjennombrudd mot kreft. Forskerforum [Fagblad]. 2017-04-03.
Redalen, Kathrine Røe. (2017) Vi har et kjempeproblem hvis skepsisen til oss øker. Universitetsavisa [Avis]. 2017-09-25.
Redalen, Kathrine Røe; Meltzer, Sebastian. (2017) OxyTarget-studien i rectumcancer - sammenhenger mellom funksjonelle MR-data, lymfeknuter, sirkulerende markører og fjernmetastaser. Kirurgisk forskningsforum ; 2017-01-12 - 2017-01-12.
Bakke, Kine Mari; Hole, Knut Håkon; Dueland, Svein; Flatmark, Kjersti; Ree, Anne Hansen; Seierstad, Therese; Redalen, Kathrine Røe. (2016) Tumour perfusion estimated from diffusion-weighted MRI of rectal cancer – an indirect marker of tumour hypoxia?. The 8th National PhD Conference in Medical Imaging . Norwegian Research School in Medical Imaging; Trondheim. 2016-11-21 - 2016-11-22.
Bakke, Kine Mari; Seierstad, Therese; Hole, Knut Håkon; Dueland, Svein; Flatmark, Kjersti; Ree, Anne Hansen; Redalen, Kathrine Røe. (2016) Histogram analysis of ADCs from DWMRI predicts tumour response and survival for rectal cancer. 35th annual meeting of the European Society for Radiotherapy & Oncology (ESTRO) ; Torino. 2016-04-29 - 2016-05-03.
Bjørnetrø, Tonje; Ree, Anne Hansen; Redalen, Kathrine Røe; Risberg, Karianne. (2016) Exosomes from hypoxic colorectal cancer cells – miRNA cargo as indicator of adverse CRC biology?. The fifth international meeting of the International Society of Extracellular Vesicles . ISEV; Rotterdam. 2016-05-04 - 2016-05-07.
Fleten, Karianne Giller; Bakke, Kine Mari; Abildgaard, Andreas; Mælandsmo, Gunhild; Redalen, Kathrine Røe; Flatmark, Kjersti. (2016) Diffusion-weighted MRI can predict response to aflibercept in in vivo models. American Association for Cancer Research (AACR) Annual Meeting . AACR; New Orleans. 2016-04-16 - 2016-04-20.
Meltzer, Sebastian; Kalanxhi, Ert; Dueland, Svein; Flatmark, Kjersti; Redalen, Kathrine Røe; Ree, Anne Hansen. (2016) Oxaliplatin-induced immune factors and long-term disease control in rectal cancer - a reflection of immunogenic tumor cell death?. AACR Annual Meeting 2016 . American Association for Cancer Research; New Orleans. 2016-04-16 - 2016-04-20.
Redalen, Kathrine Røe. (2016) Bildediagnostikk og strålebehandling av kreft. Institutt for Energiteknikk (IFE) samarbeidsmøte . Institutt for Energiteknikk (IFE); Kjeller. 2016-02-29 - 2016-02-29.
Redalen, Kathrine Røe. (2016) Forskernatt i akademiet. forskning.no [Internett]. 2016-08-16.
Redalen, Kathrine Røe. (2016) Kreftforeningen må ta bedre vare på unge forskere. forskning.no [Internett]. 2016-05-05.
Redalen, Kathrine Røe. (2016) Measures of diagnostic accuracy – basic definitions and ROC-analysis. End-points and statistics in biomarker studies and clinical trials . Regional Research Network ACREDIT; Oslo. 2016-05-19 - 2016-05-19.
Redalen, Kathrine Røe. (2016) Medical imaging in cancer biology and personalized therapy. Oslo University Hospital Research Seminar . Kathrine Røe Redalen; Rikshospitalet, Oslo. 2016-01-11 - 2016-01-11.
Redalen, Kathrine Røe; Sitter, Beathe; Bathen, Tone Frost; Grøholt, Krystyna Kotanska; Hole, Knut Håkon; Dueland, Svein; Flatmark, Kjersti; Ree, Anne Hansen; Seierstad, Therese. (2016) High tumour glycine concentration – an adverse prognostic factor in locally advanced rectal cancer. 35th annual meeting of the European Society for Radiotherapy & Oncology (ESTRO) ; Torino. 2016-04-29 - 2016-05-03.
Bakke, Kine Mari; Seierstad, Therese; Hole, Knut Håkon; Ree, Anne Hansen; Redalen, Kathrine Røe. (2015) Histogram analysis of apparent diffusion coefficients from diffusion-weighted MRI during neoadjuvant treatment of locally advanced rectal cancer predicts histologic tumor response and survival. The 7th National PhD Conference in Medical Imaging . Norwegian Research School in Medical Imaging; Oslo. 2015-11-16 - 2015-11-17.
Barua, Imon Shoumitra; Kalanxhi, Ert; Ree, Anne Hansen; Redalen, Kathrine Røe. (2015) Histone deacetylase inhibitors in combined-modality cancer treatment – experimental studies of normal tissue effects. Frampeik - Medisinstudentenes Forskningskonferanse ; Tromsø. 2015-10-30 - 2015-11-01.
Grøvik, Endre; Redalen, Kathrine Røe; Melles, Woldegabriel A; Gjesdal, Kjell-Inge. (2015) Feasibility of multi-echo dynamic MRI for simultaneous acquisition of T1-weighted and R2* contrast kinetics in rectal cancer. Biology-Guided Adaptive Radiotherapy, 13th Acta Oncologica symposium ; Århus. 2015-06-10 - 2015-06-12.
Meltzer, Sebastian; Kalanxhi, Ert; Hektoen, Helga; Dueland, Svein; Flatmark, Kjersti; Redalen, Kathrine Røe; Ree, Anne Hansen. (2015) Circulating osteoprotegerin as inflammatory mediator of toxicity and survival to combined-modality therapy in rectal cancer. European Cancer Congress 2015 . ECCO, ESMO, ESTRO, ESSO, EACR, EONS and SIOPE; Vienna. 2015-09-25 - 2015-09-29.
Meltzer, Sebastian; Kalanxhi, Ert; Hektoen, Helga; Dueland, Svein; Flatmark, Kjersti; Redalen, Kathrine Røe; Ree, Anne Hansen. (2015) Circulating tumor necrosis factor receptor (TNFR) proteins in systemic disease outcome to combined-modality radiotherapy in rectal cancer. International Conference on Molecular Targets and Cancer Therapeutics . American Association for Cancer Research; Boston, Massachusetts. 2015-11-05 - 2015-11-09.
Meltzer, Sebastian; Ree, Anne Hansen; Redalen, Kathrine Røe. (2015) The OxyTarget study – Functional MRI of Hypoxia-Mediated Rectal Cancer Aggressiveness. The 7th National PhD Conference in Medical Imaging . Norwegian Research School in Medical Imaging; Oslo. 2015-11-16 - 2015-11-17.
Redalen, Kathrine Røe. (2015) Ny dynamisk MR-sekvens for bedre karakterisering av endetarmskreft. Høstmøtet 2015 . Norsk Radiologisk Forening, Norsk Forening for Med. Fysikk; Oslo. 2015-10-20 - 2015-10-23.
Redalen, Kathrine Røe. (2015) Vil lage mer tilpasset behandling for endetarmskreft. forskning.no [Internett]. 2015-10-06.
Sivarajah, Nirujah; Ree, Anne Hansen; Kalanxhi, Ert; Redalen, Kathrine Røe; Risberg, Karianne. (2015) Identification of optimal culturing conditions for studying exosomes from normoxic and hypoxic colorectal cancer cell lines. 4th international meeting of International Society for Extracellular Vesicles (ISEV) ; 2015-04-23 - 2015-04-26.
Negard, Anne; Redalen, Kathrine Røe; Jahnsen, Jørgen; Færden, Arne Engebret; Ree, Anne Hansen; Vatn, Morten H. (2014) Crohns disease and secondary malignancy: Morphological findings with MRI and CT and how novel functional MR sequences can improve diagnostics. RSNA, Annual meeting . Radiological society of North America; Chicago. 2014-11-30 - 2014-12-05.
Redalen, Kathrine Røe. (2014) Individualisert behandling av tarmkreft. Akershus universitetssykehus åpen kveld om forskning ; 2014-04-01 - 2014-04-01.
Redalen, Kathrine Røe. (2014) OxyTarget study - Functional MRI of hypoxia-mediated rectal cancer aggressiveness. Kick-off meeting Regional Research Network ACREDIT - Advanced ColoRectal Cancer - Individualization of Therapies . Regional Research Network ACREDIT - Advanced ColoRectal Can; Oslo. 2014-10-08 - 2014-10-08.
Redalen, Kathrine Røe; Ree, Anne Hansen. (2014) Spredning av kreft via mikroblærer. Kreftforeningen [Internett]. 2014-01-09.
Tahiri, Andliena; Røe, Kathrine; de Wijn, Rik; Busch, Christian; Lønning, Per Eystein; Ree, Anne Hansen; Kristensen, Vessela N.; Geisler, Jürgen. (2012) Tyrosine kinase activity profiling of metastatic malignant melanoma: Identification of possible therapeutic targets and markers predicting response to therapy. American Association of Cancer Research ; Chicago, IL. 2012-03-31 - 2012-04-04.
Redalen, Kathrine Røe; Seierstad, Therese; Kristian, Alexandr; Mælandsmo, Gunhild; van der Kogel, Albert; Ree, Anne Hansen; Olsen, Dag Rune. (2010) Quantitative in vivo DCE MRI of prostate cancer xenografts: assessment of ADT and RT efficacy. Molecular Imaging in Radiation Oncology (MIRO) ; Brussels. 2010-03-18 - 2010-03-20.
Seierstad, Therese; Redalen, Kathrine Røe; Folkvord, Sigurd; Flatmark, Kjersti; Skretting, Arne; Olsen, Dag Rune. (2010) Early prediction of treatment response in xenografts using quantitative diffusion weighted MRI. Molecular Imaging in Radiation Oncology (MIRO) ; Brussels. 2010-03-18 - 2010-03-20.
Olsen, Dag Rune; Seierstad, Therese; Folkvord, Sigurd; Røe, Kathrine; Flatmark, Kjersti; Ree, Anne Hansen. (2007) Treatment response following combined capecitabine, oxaliplatin and radiation therapy monitored by diffusion weighted magnetic resonance imaging (DW-MRI) in a xenograft model. 14th European Cancer Conference (ECCO 14 . European Cancer Organization; Barcelona. 2007-09-23 - 2007-09-27.

Kathrine Røe Redalen

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