Background and activities

I am Associate Professor at Department of Physics, NTNU, from 2017. I obtained my PhD from the University of Oslo in 2012 with research carried out at the Norwegian Radium Hospital. 

 
Research
Research activities include functional cancer imaging (positron emission tomography (PET) and magnetic resonance imaging (MRI)), where we develop new acquisiton methods and image analysis approaches aimed at achieving a more precise cancer diagnosis, to retrieve predictive and prognostic information on treatment outcome and survival as well as improved evaluation of treatment efficacy during treatment. Further, we are using functional imaging to map the radiation sensitivity in individual tumours by utilising different approaches to quantitatively assess tumour oxygenation and vascular function, which are two important characteristics in the tumour microenvironment that affect both therapeutic response and disease outcome. Our imaging research is centred around applications in the field of radiotherapy, where we aim to improve the use of advanced imaging in radiation dose delivery and integrate PET and MRI information in modelling of both tumour response and normal tissue toxicity following radiation. We also have ongoing activity within functional MRI-based tumour segmentation approaches using machine learning.  
 
More about research activities in the Medical Radiation Physics group
 
Research projects
  • CURIE - Cancer imaging by fUnctional magnetic resonance for Radiotherapy Individualisation and Evaluation, funded by the Norwegian Cancer Society, 2019 - 2023 
  • Improved diagnostics and treatment through a state-of-the-art multi-center nuclear medicine approach: Applications in cancer and dementia (180N - Norwegian Nuclear Medicine Consortium), funded by Trond Mohn Foundation, Central Norway Regional Health Authority, St. Olavs hospital and NTNU, 2019 - 2024
  • Improved strategies for radiotherapy of prostate cancer utilizing proton therapy and advanced imaging modalities, funded by Central Norway Regional Health Authority, 2018 - 2023
  • Development of Cu-64 radiopharmaceuticals for positron emission tomography (PET) and treatment of hypoxic, aggressive cancer, funded by Central Norway Regional Health Authority, 2019 - 2022
Research group members:
Current teaching activities
 
Other
I am member of the Young Academy of Norway and the Young Committee/Physics Committee of the European Society for Radiotherapy and Oncology.
 

 

Scientific, academic and artistic work

Displaying a selection of activities. See all publications in the database

Journal publications

Others

  • Redalen, Kathrine. (2020) CURIE – Cancer imaging by functional magnetic resonance for radiotherapy individualisation and evaluation. CURIE seminar ; 2020-01-13 - 2020-01-13.
  • Redalen, Kathrine. (2020) Kunstig intelligens i stråleterapi. Seminar om stråleterapi . Akershus universitetssykehus; 2020-09-21 - 2020-09-21.
  • Redalen, Kathrine. (2020) Medical radiation physics at NTNU. Kreftklinikkens forskningsseminar . St. Olavs hospital; 2020-02-06 - 2020-02-07.
  • Redalen, Kathrine. (2020) Spot-scanning proton arc treatment. Particle therapy - ESTRO . ESTRO - European Society for Radiotherapy and Oncology; Trento. 2020-02-16 - 2020-02-20.
  • Duch, Michael Francis; De Moor, Katrien; Helland, Ingeborg Palm; Redalen, Kathrine. (2019) Fra ukjent til å bli på hils med statsråden. Universitetsavisa [Avis]. 2019-10-18.
  • Frøyen, Elin Agathe; Lyckander, Lars Gustav; Grandal, Ole Jacob; Lunder, Aida Kapic; Meltzer, Sebastian; Redalen, Kathrine; Ree, Anne Hansen; Negård, Anne. (2019) MRI of Extramural Venous Invasion in rectal cancer: assessment of the interobserver agreement and comparison with histopathology stained with hematoxylin/eosin and elastin. European Congress for Gastrointestinal and Abdominal Radiology . European Society for Gastroinestinal and Abdominal Radiolog); Roma. 2019-06-04 - 2019-06-08.
  • Knuth, Franziska; Grøndahl, Aurora Rosvoll; Torheim, Turid Katrine Gjerstad; Negård, Anne; Holmedal, Stein Harald; Bakke, Kine Mari; Meltzer, Sebastian; Futsæther, Cecilia Marie; Redalen, Kathrine. (2019) Automatic tumor delineation in rectal cancer using functional MRI and machine learning. MedFys 2019 . Norsk Forening for Medisinisk Fysikk; Kvitfjell. 2019-02-04 - 2019-02-06.
  • Knuth, Franziska; Grøndahl, Aurora Rosvoll; Torheim, Turid Katrine Gjerstad; Negård, Anne; Holmedal, Stein Harald; Bakke, Kine Mari; Meltzer, Sebastian; Futsæther, Cecilia Marie; Redalen, Kathrine. (2019) Automatic tumour delineation in rectal cancer using functional MRI and machine learning. ESTRO 38 . European Society for Radiotherapy and Oncology; Milan. 2019-04-26 - 2019-04-30.
  • Knuth, Franziska; Grøndahl, Aurora Rosvoll; Torheim, Turid Katrine Gjerstad; Negård, Anne; Holmedal, Stein Harald; Bakke, Kine Mari; Meltzer, Sebastian; Futsæther, Cecilia Marie; Redalen, Kathrine. (2019) Functional MR-based automatic tumor segmentation of rectal cancer. BiGART2019 - 18th Acta Oncologica conference ; Aarhus. 2019-05-22 - 2019-05-24.
  • Meltzer, Sebastian; Bakke, Kine Mari; Lund Rød, Karina; Dueland, Svein; Flatmark, Kjersti; Kristensen, Annette Torgunrud; Larsen, Finn Ole; Schou, Jakob Vasehus; Fuglestad, Anniken Jørlo; Kersten, Christian; Redalen, Kathrine; Ree, Anne Hansen. (2019) Gender disparities in outcome after neoadjuvant chemoradiotherapy for locally advanced rectal cancer are associated with hemodynamic differences. ESTRO 38 . European Society for Radiation Oncology; Milano. 2019-04-26 - 2019-04-30.
  • Meltzer, Sebastian; Redalen, Kathrine; Dueland, Svein; Kristensen, Annette Torgunrud; Solbakken, Arne Mide; Flatmark, Kjersti; Ree, Anne Hansen. (2019) Circulating angiogenic factors predict metastatic liver progression in rectal cancer patients given curative-intent oxaliplatin-containing neoadjuvant therapy. American Association for Cancer Research Annual Meeting . American Association for Cancer Research; Atlanta, Georgia. 2019-03-29 - 2019-04-03.
  • Redalen, Kathrine. (2019) Funksjonell MR; verktøy for prediksjon av behandlingseffekt ved rektumcancer. Multidisiplinært onkologisk GI-cancer møte . Amgen og Bayer; Trondheim. 2019-02-07 - 2019-02-08.
  • Redalen, Kathrine. (2019) Imaging biomarkers. MED3062 – Påvisning og monitorering av sykdom i laboratoriet . Universitetet i Oslo; Akershus universitetssykehus. 2019-01-21 - 2019-02-01.
  • Redalen, Kathrine. (2019) Kan bedre bildediagnostikk gjøre kreftbehandlingen enda bedre?. Temakafé for kreftpasienter og pårørende . Kreftforeningen; Steinkjer. 2019-09-25 - 2019-09-25.
  • Redalen, Kathrine. (2019) MRI-based dose-painting of rectal cancer. 34th Conference on Clinical and Experimental Research in Radiation Oncology (CERRO) . ESTRO (European Society for Radiotherapy and Oncology); Le Menuires. 2019-01-19 - 2019-01-26.
  • Redalen, Kathrine. (2019) Maskinlæring i stråleterapi. Norsk stråleterapimøte . Norsk forening for medisinsk fysikk; Oslo. 2019-09-19 - 2019-09-20.
  • Redalen, Kathrine. (2019) What characterizes a good relationship between a supervisor and a student?. TEKNA seminar - Academic supervision . TEKNA; Litteraturhuset, Trondheim. 2019-03-07 - 2019-03-07.
  • Bakke, Kine Mari; Meltzer, Sebastian; Lyckander, Lars Gustav; Holmedal, Stein Harald; Negård, Anne; Gjesdal, Kjell-Inge; Grøvik, Endre; Redalen, Kathrine. (2018) Predicting tumour response to chemoradiotherapy in rectal cancer using dynamic contrast enhanced MRI. European Society for Radiotherapy and Oncology (ESTRO) 37th annual meeting . ESTRO (European Society for Radiotherapy and Oncology); Barcelona. 2018-04-20 - 2018-04-24.
  • Melles, Woldegabriel A; Meltzer, Sebastian; Bakke, Kine Mari; Storaas H, Tryggve; Holmedal, Stein Harald; Redalen, Kathrine; Negård, Anne. (2018) Comparison of Apparent Diffusion Coefficients from Diffusion-Weighted Imaging of Rectal Cancer at different MR scanners. European Congress of Radiology 2018 . European Society of Radiology; Wien. 2018-02-28 - 2018-03-02.
  • Redalen, Kathrine. (2018) Baseline dynamic R2* MRI in rectal cancer is associated with chemoradiotherapy outcome. 6th MR in RT symposium ; Utrecht. 2018-06-30 - 2018-07-03.
  • Redalen, Kathrine. (2018) Biomarker discovery. 2nd ESTRO Physics workshop . ESTRO (European Society for Radiotherapy and Oncology); Malaga. 2018-10-26 - 2018-10-27.
  • Redalen, Kathrine. (2018) Bruk av MR for utredning og behandling av kreft med spesielt henblikk på colorectal og prostata. Seminar Kreftklinikken, St. Olavs hospital ; 2018-04-05 - 2018-04-05.
  • Redalen, Kathrine. (2018) MRI in radiotherapy. MRI in radiotherapy . Kreftklinikken, St. Olavs hospital og Inst. for fysikk, NTNU; Trondheim. 2018-12-05 - 2018-12-05.
  • Redalen, Kathrine. (2018) Motivasjonsforedrag. Fakultet for naturvitenskap sin velkomstdag for jenter . Fakultet for naturvitenskap; Trondheim. 2018-08-12 - 2018-08-12.
  • Syversen, Ingrid Framås; Bakke, Kine Mari; Grøvik, Endre; Negård, Anne; Holmedal, Stein Harald; Lyckander, Lars Gustav; Gjesdal, Kjell-Inge; Meltzer, Sebastian; Redalen, Kathrine. (2018) Prediction of chemoradiotherapy response in rectal cancer using static and dynamic R2* MRI. European Society for Radiotherapy and Oncology (ESTRO) 37th annual meeting . ESTRO (European Society for Radiotherapy and Oncology); Barcelona. 2018-04-20 - 2018-04-24.
  • Bakke, Kine Mari; Hole, Knut Håkon; Dueland, Svein; Grøholt, Krystyna Kotanska; Ree, Anne Hansen; Flatmark, Kjersti; Seierstad, Therese; Redalen, Kathrine Røe. (2017) Diffusion-weighted MRI of rectal cancer: baseline tumour perfusion fraction predicts chemoradiotherapy response and survival. International Society for Magnetic Resonance in Medicine 25th Annual Meeting . International Society for Magnetic Resonance in Medicine; Hawaii. 2017-04-22 - 2017-04-27.
  • Barua, Imon Shoumitra; Ree, Anne Hansen; Sønstevold, Linda; Redalen, Kathrine Røe; Kalanxhi, Ert. (2017) Mechanisms of normal tissue toxicity from SAHA - an HDAC inhibitor and radiosensitizer. ESTRO 36 - Annual Meeting of the European Society for Radiotherapy & Oncology . European Society for Radiotherapy & Oncology; Wien. 2017-05-05 - 2017-05-09.
  • Grøvik, Endre; Redalen, Kathrine Røe; Storås, Tryggve; Holmedal, Stein Harald; Negard, Anne; Ree, Anne Hansen; Meltzer, Sebastian; Bjørnerud, Atle; Gjesdal, Kjell-Inge. (2017) Improved sensitivity for rectal cancer differentiation by T2*-correction in DCE-MRI. International Society for Magnetic Resonance in Medicine 25th Annual Meeting . International Society for Magnetic Resonance in Medicine; Hawaii. 2017-04-22 - 2017-04-27.
  • Meltzer, Sebastian; Lyckander, Lars Gustav; Ree, Anne Hansen; Redalen, Kathrine Røe. (2017) Circulating angiogenesis factors predicting poor chemoradiotherapy outcome in rectal cancer. ESTRO 36 - Annual Meeting of the European Society for Radiotherapy & Oncology . European Society for Radiotherapy & Oncology; Wien. 2017-05-05 - 2017-05-09.
  • Meltzer, Sebastian; Ree, Anne Hansen; Lyckander, Lars Gustav; Redalen, Kathrine Røe. (2017) Circulating exosomal miRNA related to chemoradiotherapy outcome in locally advanced rectal cancer. ESTRO 36 - Annual Meeting of the European Society for Radiotherapy & Oncology . European Society for Radiotherapy & Oncology; Wien. 2017-05-05 - 2017-05-09.
  • Redalen, Kathrine Røe. (2017) Extracellular vesicles in radiation oncology. ESTRO 36 - Annual Meeting of the European Society for Radiotherapy & Oncology . European Society for Radiotherapy & Oncology; Wien. 2017-05-05 - 2017-05-09.
  • Redalen, Kathrine Røe. (2017) Functional MRI in metastatic colorectal cancer. Regional Research Network Acredit - Advanced Colorectal Cancer Individualization of Therapies ; 2017-11-02 - 2017-11-03.
  • Redalen, Kathrine Røe. (2017) Tok sjansen, fikk gjennombrudd mot kreft. Forskerforum [Fagblad]. 2017-04-03.
  • Redalen, Kathrine Røe. (2017) Vi har et kjempeproblem hvis skepsisen til oss øker. Universitetsavisa [Avis]. 2017-09-25.
  • Redalen, Kathrine Røe; Meltzer, Sebastian. (2017) OxyTarget-studien i rectumcancer - sammenhenger mellom funksjonelle MR-data, lymfeknuter, sirkulerende markører og fjernmetastaser. Kirurgisk forskningsforum ; 2017-01-12 - 2017-01-12.
  • Bakke, Kine Mari; Hole, Knut Håkon; Dueland, Svein; Flatmark, Kjersti; Ree, Anne Hansen; Seierstad, Therese; Redalen, Kathrine Røe. (2016) Tumour perfusion estimated from diffusion-weighted MRI of rectal cancer – an indirect marker of tumour hypoxia?. The 8th National PhD Conference in Medical Imaging . Norwegian Research School in Medical Imaging; Trondheim. 2016-11-21 - 2016-11-22.
  • Bakke, Kine Mari; Seierstad, Therese; Hole, Knut Håkon; Dueland, Svein; Flatmark, Kjersti; Ree, Anne Hansen; Redalen, Kathrine Røe. (2016) Histogram analysis of ADCs from DWMRI predicts tumour response and survival for rectal cancer. 35th annual meeting of the European Society for Radiotherapy & Oncology (ESTRO) ; Torino. 2016-04-29 - 2016-05-03.
  • Bjørnetrø, Tonje; Ree, Anne Hansen; Redalen, Kathrine Røe; Risberg, Karianne. (2016) Exosomes from hypoxic colorectal cancer cells – miRNA cargo as indicator of adverse CRC biology?. The fifth international meeting of the International Society of Extracellular Vesicles . ISEV; Rotterdam. 2016-05-04 - 2016-05-07.
  • Fleten, Karianne Giller; Bakke, Kine Mari; Abildgaard, Andreas; Mælandsmo, Gunhild; Redalen, Kathrine Røe; Flatmark, Kjersti. (2016) Diffusion-weighted MRI can predict response to aflibercept in in vivo models. American Association for Cancer Research (AACR) Annual Meeting . AACR; New Orleans. 2016-04-16 - 2016-04-20.
  • Meltzer, Sebastian; Kalanxhi, Ert; Dueland, Svein; Flatmark, Kjersti; Redalen, Kathrine Røe; Ree, Anne Hansen. (2016) Oxaliplatin-induced immune factors and long-term disease control in rectal cancer - a reflection of immunogenic tumor cell death?. AACR Annual Meeting 2016 . American Association for Cancer Research; New Orleans. 2016-04-16 - 2016-04-20.
  • Redalen, Kathrine Røe. (2016) Bildediagnostikk og strålebehandling av kreft. Institutt for Energiteknikk (IFE) samarbeidsmøte . Institutt for Energiteknikk (IFE); Kjeller. 2016-02-29 - 2016-02-29.
  • Redalen, Kathrine Røe. (2016) Forskernatt i akademiet. forskning.no [Internett]. 2016-08-16.
  • Redalen, Kathrine Røe. (2016) Kreftforeningen må ta bedre vare på unge forskere. forskning.no [Internett]. 2016-05-05.
  • Redalen, Kathrine Røe. (2016) Measures of diagnostic accuracy – basic definitions and ROC-analysis. End-points and statistics in biomarker studies and clinical trials . Regional Research Network ACREDIT; Oslo. 2016-05-19 - 2016-05-19.
  • Redalen, Kathrine Røe. (2016) Medical imaging in cancer biology and personalized therapy. Oslo University Hospital Research Seminar . Kathrine Røe Redalen; Rikshospitalet, Oslo. 2016-01-11 - 2016-01-11.
  • Redalen, Kathrine Røe; Sitter, Beathe; Bathen, Tone Frost; Grøholt, Krystyna Kotanska; Hole, Knut Håkon; Dueland, Svein; Flatmark, Kjersti; Ree, Anne Hansen; Seierstad, Therese. (2016) High tumour glycine concentration – an adverse prognostic factor in locally advanced rectal cancer. 35th annual meeting of the European Society for Radiotherapy & Oncology (ESTRO) ; Torino. 2016-04-29 - 2016-05-03.
  • Bakke, Kine Mari; Seierstad, Therese; Hole, Knut Håkon; Ree, Anne Hansen; Redalen, Kathrine Røe. (2015) Histogram analysis of apparent diffusion coefficients from diffusion-weighted MRI during neoadjuvant treatment of locally advanced rectal cancer predicts histologic tumor response and survival. The 7th National PhD Conference in Medical Imaging . Norwegian Research School in Medical Imaging; Oslo. 2015-11-16 - 2015-11-17.
  • Barua, Imon Shoumitra; Kalanxhi, Ert; Ree, Anne Hansen; Redalen, Kathrine Røe. (2015) Histone deacetylase inhibitors in combined-modality cancer treatment – experimental studies of normal tissue effects. Frampeik - Medisinstudentenes Forskningskonferanse ; Tromsø. 2015-10-30 - 2015-11-01.
  • Grøvik, Endre; Redalen, Kathrine Røe; Melles, Woldegabriel A; Gjesdal, Kjell-Inge. (2015) Feasibility of multi-echo dynamic MRI for simultaneous acquisition of T1-weighted and R2* contrast kinetics in rectal cancer. Biology-Guided Adaptive Radiotherapy, 13th Acta Oncologica symposium ; Århus. 2015-06-10 - 2015-06-12.
  • Meltzer, Sebastian; Kalanxhi, Ert; Hektoen, Helga; Dueland, Svein; Flatmark, Kjersti; Redalen, Kathrine Røe; Ree, Anne Hansen. (2015) Circulating osteoprotegerin as inflammatory mediator of toxicity and survival to combined-modality therapy in rectal cancer. European Cancer Congress 2015 . ECCO, ESMO, ESTRO, ESSO, EACR, EONS and SIOPE; Vienna. 2015-09-25 - 2015-09-29.
  • Meltzer, Sebastian; Kalanxhi, Ert; Hektoen, Helga; Dueland, Svein; Flatmark, Kjersti; Redalen, Kathrine Røe; Ree, Anne Hansen. (2015) Circulating tumor necrosis factor receptor (TNFR) proteins in systemic disease outcome to combined-modality radiotherapy in rectal cancer. International Conference on Molecular Targets and Cancer Therapeutics . American Association for Cancer Research; Boston, Massachusetts. 2015-11-05 - 2015-11-09.
  • Meltzer, Sebastian; Ree, Anne Hansen; Redalen, Kathrine Røe. (2015) The OxyTarget study – Functional MRI of Hypoxia-Mediated Rectal Cancer Aggressiveness. The 7th National PhD Conference in Medical Imaging . Norwegian Research School in Medical Imaging; Oslo. 2015-11-16 - 2015-11-17.
  • Redalen, Kathrine Røe. (2015) Ny dynamisk MR-sekvens for bedre karakterisering av endetarmskreft. Høstmøtet 2015 . Norsk Radiologisk Forening, Norsk Forening for Med. Fysikk; Oslo. 2015-10-20 - 2015-10-23.
  • Redalen, Kathrine Røe. (2015) Vil lage mer tilpasset behandling for endetarmskreft. forskning.no [Internett]. 2015-10-06.
  • Sivarajah, Nirujah; Ree, Anne Hansen; Kalanxhi, Ert; Redalen, Kathrine Røe; Risberg, Karianne. (2015) Identification of optimal culturing conditions for studying exosomes from normoxic and hypoxic colorectal cancer cell lines. 4th international meeting of International Society for Extracellular Vesicles (ISEV) ; 2015-04-23 - 2015-04-26.
  • Negard, Anne; Redalen, Kathrine Røe; Jahnsen, Jørgen; Færden, Arne Engebret; Ree, Anne Hansen; Vatn, Morten H. (2014) Crohns disease and secondary malignancy: Morphological findings with MRI and CT and how novel functional MR sequences can improve diagnostics. RSNA, Annual meeting . Radiological society of North America; Chicago. 2014-11-30 - 2014-12-05.
  • Redalen, Kathrine Røe. (2014) Individualisert behandling av tarmkreft. Akershus universitetssykehus åpen kveld om forskning ; 2014-04-01 - 2014-04-01.
  • Redalen, Kathrine Røe. (2014) OxyTarget study - Functional MRI of hypoxia-mediated rectal cancer aggressiveness. Kick-off meeting Regional Research Network ACREDIT - Advanced ColoRectal Cancer - Individualization of Therapies . Regional Research Network ACREDIT - Advanced ColoRectal Can; Oslo. 2014-10-08 - 2014-10-08.
  • Redalen, Kathrine Røe; Ree, Anne Hansen. (2014) Spredning av kreft via mikroblærer. Kreftforeningen [Internett]. 2014-01-09.
  • Tahiri, Andliena; Røe, Kathrine; de Wijn, Rik; Busch, Christian; Lønning, Per Eystein; Ree, Anne Hansen; Kristensen, Vessela N.; Geisler, Jürgen. (2012) Tyrosine kinase activity profiling of metastatic malignant melanoma: Identification of possible therapeutic targets and markers predicting response to therapy. American Association of Cancer Research ; Chicago, IL. 2012-03-31 - 2012-04-04.
  • Redalen, Kathrine Røe; Seierstad, Therese; Kristian, Alexandr; Mælandsmo, Gunhild; van der Kogel, Albert; Ree, Anne Hansen; Olsen, Dag Rune. (2010) Quantitative in vivo DCE MRI of prostate cancer xenografts: assessment of ADT and RT efficacy. Molecular Imaging in Radiation Oncology (MIRO) ; Brussels. 2010-03-18 - 2010-03-20.
  • Seierstad, Therese; Redalen, Kathrine Røe; Folkvord, Sigurd; Flatmark, Kjersti; Skretting, Arne; Olsen, Dag Rune. (2010) Early prediction of treatment response in xenografts using quantitative diffusion weighted MRI. Molecular Imaging in Radiation Oncology (MIRO) ; Brussels. 2010-03-18 - 2010-03-20.
  • Olsen, Dag Rune; Seierstad, Therese; Folkvord, Sigurd; Røe, Kathrine; Flatmark, Kjersti; Ree, Anne Hansen. (2007) Treatment response following combined capecitabine, oxaliplatin and radiation therapy monitored by diffusion weighted magnetic resonance imaging (DW-MRI) in a xenograft model. 14th European Cancer Conference (ECCO 14 . European Cancer Organization; Barcelona. 2007-09-23 - 2007-09-27.