Optical imaging

IVIS Spectrum In Vivo Imaging System

High-sensitivity in vivo imaging of fluorescence and bioluminescence
High throughput (5 mice)
High resolution (to 20 microns) with 3.9 cm field of view

Fluorescence imaging of healthy mice with (left) and without (right) fluorescent nanoparticles injection. Image courtesy: Caroline Einen

Bioluminescence imaging monitoring orthotopic breast tumor growth. Image courtesy: Caroline Einen

Highlighted publications

Hyldbakk, Astrid; Fleten, Karianne Giller; Snipstad, Sofie; Åslund, Andreas; Davies, Catharina de Lange; Flatmark, Kjersti; Mørch, Ýrr Asbjørg. Intraperitoneal administration of cabazitaxel-loaded nanoparticles in peritoneal metastasis models. Nanomedicine: Nanotechnology, Biology and Medicine 2023; Volume 48. p. 1-11. doi: 10.1016/j.nano.2023.102656. PMID: 36646195.

Pandya, Abhilash D.; Iversen, Tore Geir; Moestue, Siver Andreas; Grinde, Maria Tunset; Mørch, Ýrr Asbjørg; Snipstad, Sofie; Åslund, Andreas; Øy, Geir Frode; Kildal, Wanja; Engebråten, Olav; Sandvig, Kirsten; Skotland, Tore; Mælandsmo, Gunhild Mari. Biodistribution of Poly(alkyl cyanoacrylate) Nanoparticles in Mice and Effect on Tumor Infiltration of Macrophages into a Patient-Derived Breast Cancer Xenograft. Nanomaterials (Basel). 2021 Apr 28;11(5):1140. doi: 10.3390/nano11051140. PMID: 33924869. PMCID: PMC8145722

Fusser, Markus; Øverbye, Anders; Pandya, Abhilash D.; Mørch, Ýrr Asbjørg; Borgos, Sven Even F.; Kildal, Wanja; Snipstad, Sofie; Sulheim, Einar; Fleten, Karianne Giller; Askautrud, Hanne Arenberg; Engebråten, Olav; Flatmark, Kjersti; Iversen, Tore Geir; Sandvig, Kirsten; Skotland, Tore; Mælandsmo, Gunhild Mari. Cabazitaxel-loaded Poly(2-ethylbutyl cyanoacrylate) nanoparticles improve treatment efficacy in a patient derived breast cancer xenograft. Journal of Controlled Release 2018 ;Volume 293. p. 183-192. doi: 10.1016/j.jconrel.2018.11.029. PMID: 30529259