TKJ4130 - Organic Synthesis, Laboratory


Examination arrangement

Examination arrangement: Work
Grade: Letter grades

Evaluation Weighting Duration Grade deviation Examination aids
Work 100/100

Course content

Organic chemistry laboratory, advanced organic synthesis, lab safety, use of SciFinder program, mounting of lab equipment, reaction under inert atmosphere, extraction, crystallisation, distillation, column chromatography, the use of rotavapor, NMR analysis, thin layer chromatography, IR-spectroscopy, UV-spectroscopy, optical rotation, literature investigations, reporting.

Learning outcome

The student should upon completion of the course: (i) make a hazard evaluation of the chemistry based on material safety datasheets and the lab recipe, (ii) perform reactions of different kinds also under water free/inert conditions, (iii) find relevant literature using SciFinder and eventually Reaxys, (iv) analyse the reaction progress of a reaction, (v) interpretate spectroscopic and analytical data of various kinds, (vi) be able to purify an organic compound using extraction, crystallisation, distillation and column chromatography and (vii) be able to report the findings, evaluate possible errors and pinpoint improvement potentials.

Learning methods and activities

Laboratory work, preparation and report writing. (215 hours). As a part of the compulsory laboratory course is a compulsory digital HSE lecture. The HSE lecture/exam must be approved before access to the lab course will be given. A work shop in literature search, NMR structure determination and how to write the reports will be given in the week before course start, preferably in the afternoon. English teaching by request.

Further on evaluation

Each student must complete 215 hours work in total (no exam) :

1. Seven handbook syntheses in 14 laboratory working days, in total 84 hours

2. An individual synthesis project in a research group (2-3 weeks approx. 30 h) (In total 115 hours lab work)

3. SJA-scheme, literature studies, lab journal and reports, in total 100 hours

Criteria for assessment:

• HSE / SJA • Examinations • Reports (quality and punctuality) • Product yields • Product quality

• Work routines in the laboratory.

Required previous knowledge

Knowledge corresponding to TKJ4102/TKJ4100/KJ1020, TKJ4150 and KJ2022 or similar courses. If TKJ4150 is not already passed, it must be taken the same semester as TKJ4130. Admission to the course is restricted to students with this course as mandatory in their program. Others can apply for eventual free places.

Course materials

P.B. Cranwell, L.M. Harwood, C. S. Moody: Experimental Organic Chemistry 3rd ed., Wiley 2017. Distributed copies.

Credit reductions

Course code Reduction From To
SIK3066 7.5
KJ2024 7.5 SPRING 2006
More on the course



Version: 1
Credits:  7.5 SP
Study level: Second degree level


Term no.: 1
Teaching semester:  SPRING 2025

Language of instruction: English

Location: Trondheim

Subject area(s)
  • Organic Chemistry
  • Chemistry
  • Technological subjects
Contact information
Course coordinator: Lecturer(s):

Department with academic responsibility
Department of Chemistry


Examination arrangement: Work

Term Status code Evaluation Weighting Examination aids Date Time Examination system Room *
Spring ORD Work 100/100 INSPERA
Room Building Number of candidates
  • * The location (room) for a written examination is published 3 days before examination date. If more than one room is listed, you will find your room at Studentweb.

For more information regarding registration for examination and examination procedures, see "Innsida - Exams"

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